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Fixes #2929 - Intestinal tuft cell textual definition #2935

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Feb 11, 2025
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Fixes #2929 - Intestinal tuft cell textual definition #2935

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Fixes #2929 - Intestinal tuft cell textual definition
Caroline-99 Feb 6, 2025
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Merge branch 'master' into 2929-text-def-intestinal-tuft-cell
Caroline-99 Feb 11, 2025
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2 changes: 1 addition & 1 deletion src/ontology/cl-edit.owl
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Expand Up @@ -25005,7 +25005,7 @@ SubClassOf(obo:CL_0019031 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_4047017))

# Class: obo:CL_0019032 (intestinal tuft cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22527717") Annotation(oboInOwl:hasDbXref "PMID:39358509") obo:IAO_0000115 obo:CL_0019032 "Any brush cell that is part of the intestinal epithelium.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22527717") Annotation(oboInOwl:hasDbXref "PMID:39358509") Annotation(oboInOwl:hasDbXref "PMID:29714721") Annotation(oboInOwl:hasDbXref "PMID:35237268") obo:IAO_0000115 obo:CL_0019032 "A tuft cell that is part of the intestinal epithelium, characterized by a distinctive apical tuft and lateral cytospinules connecting to neighbouring cells. This cell senses luminal stimuli via taste receptors and succinate signalling, initiating type 2 immune responses through the secretion of interleukin-25 while modulating epithelial regeneration through prostaglandin synthesis. It expresses key molecular markers such as doublecortin-like kinase 1 (DCLK1) in mice (Hendel et al., 2022), and KIT proto-oncogene in humans (Huang et al., 2024). Developed from intestinal crypt stem cells, this cell requires transcription factor POU2F3 for its development.")
AnnotationAssertion(terms:contributor obo:CL_0019032 <https://orcid.org/0000-0003-2034-601X>)
AnnotationAssertion(terms:date obo:CL_0019032 "2020-10-15T12:47:46Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22527717") oboInOwl:hasExactSynonym obo:CL_0019032 "intestinal brush cell")
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