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Fixes #2904 - NTR subclasses of nasal tuft cell #2936

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merged 3 commits into from
Feb 11, 2025
Merged

Fixes #2904 - NTR subclasses of nasal tuft cell #2936

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2766ed0
Fixes #2904 - NTR subclasses of nasal tuft cell
Caroline-99 Feb 6, 2025
bbee75a
Merge branch 'master' into 2904-ntr-subclasses-of-tuft-cell-of-nasal-…
Caroline-99 Feb 11, 2025
1e6c166
Update cl-edit.owl
Caroline-99 Feb 11, 2025
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30 changes: 28 additions & 2 deletions src/ontology/cl-edit.owl
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Original file line number Diff line number Diff line change
Expand Up @@ -3156,6 +3156,8 @@ Declaration(Class(obo:CL_4052033))
Declaration(Class(obo:CL_4052034))
Declaration(Class(obo:CL_4052035))
Declaration(Class(obo:CL_4052036))
Declaration(Class(obo:CL_4052037))
Declaration(Class(obo:CL_4052038))
Declaration(Class(obo:CL_4052048))
Declaration(Class(obo:CL_4052049))
Declaration(Class(obo:CP_0000000))
Expand Down Expand Up @@ -15568,9 +15570,10 @@ AnnotationAssertion(terms:contributor obo:CL_0002167 <https://orcid.org/0000-000
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002167 "2010-08-26T01:47:13Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002167 "FMA:67870")
AnnotationAssertion(rdfs:label obo:CL_0002167 "olfactory epithelial cell")
EquivalentClasses(obo:CL_0002167 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050911)))
EquivalentClasses(obo:CL_0002167 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001997)))
SubClassOf(obo:CL_0002167 obo:CL_0000098)
SubClassOf(obo:CL_0002167 obo:CL_0000710)
SubClassOf(obo:CL_0002167 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050911))

# Class: obo:CL_0002168 (border cell of cochlea)

Expand All @@ -15589,7 +15592,7 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002169 "2010-08-26T01:58:54Z"
AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002169 "horizontal basal cell")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002169 "FMA:62303")
AnnotationAssertion(rdfs:label obo:CL_0002169 "basal cell of olfactory epithelium")
EquivalentClasses(obo:CL_0002169 ObjectIntersectionOf(obo:CL_0002167 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001997)))
EquivalentClasses(obo:CL_0002169 ObjectIntersectionOf(obo:CL_0002167 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000482)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002169 obo:CL_0002167)

# Class: obo:CL_0002170 (keratinized cell of the oral mucosa)
Expand Down Expand Up @@ -33617,6 +33620,29 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38306414") oboInOwl:hasE
AnnotationAssertion(rdfs:label obo:CL_4052036 "tuft cell of nasal cavity")
EquivalentClasses(obo:CL_4052036 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005384)))

# Class: obo:CL_4052037 (tuft cell of olfactory epithelium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38306414") Annotation(oboInOwl:hasDbXref "doi:/10.1101/2022.09.26.509561") obo:IAO_0000115 obo:CL_4052037 "A tuft cell that is part of the olfactory epithelium, characterized by a globular body and the expression of neurogranin (Nrgn) in mice. This cell plays a crucial role in allergen recognition and regulating olfactory stem cell proliferation via TRPM5-dependent ATP sensing and cysteinyl leukotriene production. Unlike nasal respiratory tuft cells, it has low to absent expression of taste receptors, including the G protein Gα gustducin, and rarely contacts olfactory sensory neurons directly.")
AnnotationAssertion(terms:contributor obo:CL_4052037 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052037 "2025-02-06T15:03:53Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38306414") oboInOwl:hasExactSynonym obo:CL_4052037 "olfactory tuft cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38306414") oboInOwl:hasRelatedSynonym obo:CL_4052037 "TRPM5+ microvillous cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38306414") oboInOwl:hasRelatedSynonym obo:CL_4052037 "tuft-microvillous cell")
AnnotationAssertion(rdfs:label obo:CL_4052037 "tuft cell of olfactory epithelium")
EquivalentClasses(obo:CL_4052037 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001997)))
SubClassOf(obo:CL_4052037 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0072091))

# Class: obo:CL_4052038 (tuft cell of nasal cavity respiratory epithelium)

AnnotationAssertion(obo:IAO_0000115 obo:CL_4052038 "A tuft cell that is part of the nasal cavity respiratory epithelium. Acting as a chemosensor, it detects bitter taste ligands and bacterial signals via taste receptors, maintaining epithelial-microbial homeostasis by stimulating antimicrobial peptide secretion from adjacent epithelial cells. This cell is a major source of IL-25, promoting type 2 immune responses and potentially contributing to chronic rhinosinusitis (O'Leary et al., 2019).")
AnnotationAssertion(terms:contributor obo:CL_4052038 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052038 "2025-02-06T15:28:14Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38306414") oboInOwl:hasRelatedSynonym obo:CL_4052038 "Gɑ-gustducin high respiratory tuft cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38306414") oboInOwl:hasRelatedSynonym obo:CL_4052038 "nasal respiratory solitary chemosensory cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38306414") oboInOwl:hasRelatedSynonym obo:CL_4052038 "tuft-solitary chemosensory cell")
AnnotationAssertion(rdfs:label obo:CL_4052038 "tuft cell of nasal cavity respiratory epithelium")
EquivalentClasses(obo:CL_4052038 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005385)))

# Class: obo:CL_4052048 (intercalated cell of salivary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30855909") Annotation(oboInOwl:hasDbXref "PMID:35799078") Annotation(oboInOwl:hasDbXref "PMID:36726292") Annotation(oboInOwl:hasDbXref "PMID:37724716") obo:IAO_0000115 obo:CL_4052048 "A cuboidal epithelial cell that is part of the intercalated duct of salivary gland. This cell expresses proteins commonly associated with acinar cells and displays calcium signaling characteristics similar to secretory cells, indicating an active role in the secretory process rather than ion reabsorption.")
Expand Down