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Fixes #2586 NTR-enteroendocrine progenitor #2588

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Sep 24, 2024
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14 changes: 14 additions & 0 deletions src/ontology/cl-edit.owl
Original file line number Diff line number Diff line change
Expand Up @@ -3074,6 +3074,7 @@ Declaration(Class(obo:CL_4052001))
Declaration(Class(obo:CL_4052002))
Declaration(Class(obo:CL_4052003))
Declaration(Class(obo:CL_4052004))
Declaration(Class(obo:CL_4052006))
Declaration(Class(obo:CL_4052048))
Declaration(Class(obo:CL_4052049))
Declaration(Class(obo:CP_0000000))
Expand Down Expand Up @@ -32490,6 +32491,19 @@ AnnotationAssertion(rdfs:label obo:CL_4052004 "intestinal fibroblastic reticular
SubClassOf(obo:CL_4052004 obo:CL_0009101)
SubClassOf(obo:CL_4052004 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001962))

# Class: obo:CL_4052006 (intestinal enteroendocrine progenitor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31756561") Annotation(oboInOwl:hasDbXref "PMID:32531023") Annotation(oboInOwl:hasDbXref "PMID:35913117") Annotation(oboInOwl:hasDbXref "PMID:38260422") Annotation(oboInOwl:hasDbXref "doi:/10.1038/s41467-021-27901-5") obo:IAO_0000115 obo:CL_4052006 "An epithelial cell that is part of the crypt of Lieberkuhn, originating from intestinal stem cells and giving rise to enteroendocrine cells (EECs). In mouse and human, this cell can be characterized by the expression of Neurog3, and has the ability to proliferate and differentiate into multiple EEC subtypes. Its proliferative potential contributes to crypt growth, distinguishing it from fully differentiated EECs.")
AnnotationAssertion(terms:contributor obo:CL_4052006 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052006 "2024-09-20T12:13:26Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31756561") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052006 "EEC Progenitor")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25670791") rdfs:comment obo:CL_4052006 "The EEC progenitor is also present in other organisms; for example, flies have EEC progenitors but lack intestinal crypts and do not express the same markers. Instead, they are Dl+ and Pros+.")
AnnotationAssertion(rdfs:label obo:CL_4052006 "intestinal enteroendocrine progenitor")
SubClassOf(obo:CL_4052006 obo:CL_0002563)
SubClassOf(obo:CL_4052006 obo:CL_0011026)
SubClassOf(obo:CL_4052006 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011184))
SubClassOf(obo:CL_4052006 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002250))

# Class: obo:CL_4052048 (intercalated cell of salivary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30855909") Annotation(oboInOwl:hasDbXref "PMID:35799078") Annotation(oboInOwl:hasDbXref "PMID:36726292") Annotation(oboInOwl:hasDbXref "PMID:37724716") obo:IAO_0000115 obo:CL_4052048 "A cuboidal epithelial cell that is part of the intercalated duct of salivary gland. This cell expresses proteins commonly associated with acinar cells and displays calcium signaling characteristics similar to secretory cells, indicating an active role in the secretory process rather than ion reabsorption.")
Expand Down
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