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GitHub-AmlodipineExample - added more of the detail needed for the CM…
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…C queries

Signed-off-by: Elisa Kendall <[email protected]>
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@ElisaKendall
ElisaKendall committed Jan 13, 2025
1 parent 367941e commit a807f90
Showing 1 changed file with 37 additions and 6 deletions.
43 changes: 37 additions & 6 deletions EXT/Examples/AmlodipineExample.rdf
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Original file line number Diff line number Diff line change
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<idmp-sub:hasStructure rdf:resource="https://spor.ema.europa.eu/v2/SubstanceDefinition/100000085259-MolecularStructure"/>
<idmp-sub:hasSubstanceName rdf:resource="https://gsrs.ncats.nih.gov/api/v1/substances/1J444QC288-CommonName-English-amlodipine_INN"/>
<idmp-sub:hasSubstanceName rdf:resource="https://gsrs.ncats.nih.gov/api/v1/substances/1J444QC288-OfficialName-English"/>
<cmns-dsg:hasName rdf:resource="&idmp-amp;MaterialName-InternalAmlodipineMaterialName"/>
<cmns-id:isIdentifiedBy rdf:resource="&idmp-amp;MaterialIdentifier-InternalAmlodipineIdentifier"/>
<cmns-id:isIdentifiedBy rdf:resource="&idmp-amp;SubstanceIdentifier-InternalAmlodipineIdentifier"/>
</owl:NamedIndividual>
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<cmns-txt:hasTextValue>MAT006</cmns-txt:hasTextValue>
</owl:NamedIndividual>

<owl:NamedIndividual rdf:about="&idmp-amp;MaterialName-InternalAmlodipineMaterialName">
<rdf:type rdf:resource="&idmp-sub;MaterialName"/>
<rdfs:label>material name - internal Amlodipine name</rdfs:label>
<skos:definition>designation for the physical substance Amlodipine inside some corporate manufacturing environment</skos:definition>
<cmns-dsg:isNameOf rdf:resource="&idmp-amp;AmlodipinePhysicalSubstance"/>
<cmns-txt:hasTextValue>Amlodipine</cmns-txt:hasTextValue>
</owl:NamedIndividual>

<owl:NamedIndividual rdf:about="&idmp-amp;MicrocrystallineCelluloseAsexcipientInNorvasc">
<rdf:type rdf:resource="&idmp-sub;Excipient"/>
<rdfs:label>Norvasc, excipient, Microcrystalline cellulose</rdfs:label>
Expand All @@ -1128,11 +1137,9 @@
<owl:NamedIndividual rdf:about="&idmp-amp;Norvasc-ManufacturedItem-5mgTablet">
<rdf:type rdf:resource="&idmp-sub;ManufacturedItem"/>
<rdfs:label>Norvasc, manufactured item, 5mg tablet</rdfs:label>
<skos:definition>manufactured item that is a besylate salt of amlodipine, a long-acting long-acting calcium channel blocker (CCB), used to treat high blood pressure (hypertension) and a type of chest pain called angina</skos:definition>
<skos:definition>specification for the manufactured item that is a besylate salt of amlodipine, a long-acting long-acting calcium channel blocker (CCB), used to treat high blood pressure (hypertension) and a type of chest pain called angina</skos:definition>
<idmp-uom:hasUnitOfPresentation rdf:resource="https://spor.ema.europa.eu/v1/lists/200000000014/terms/200000002152"/>
<idmp-mprd:hasDoseForm rdf:resource="&idmp-amp;Norvasc-DoseForm"/>
<idmp-mprd:isProducedAtManufacturingSite rdf:resource="&idmp-amp;PGSKalamazooManufacturingSite"/>
<idmp-mprd:isProducedByManufacturingOperation rdf:resource="&idmp-amp;PGSKalamazooOperation"/>
<cmns-col:comprises rdf:resource="https://spor.ema.europa.eu/v2/SubstanceDefinition/100000090079"/>
<cmns-dsg:isDefinedIn rdf:resource="&idmp-amp;NorvascComposition"/>
<cmns-prd:isProducedBy rdf:resource="&idmp-amp;PfizerLaboratoriesAsManufacturer"/>
Expand All @@ -1148,6 +1155,16 @@
<cmns-dsg:isDefinedIn rdf:resource="&idmp-amp;NorvascComposition"/>
</owl:NamedIndividual>

<owl:NamedIndividual rdf:about="&idmp-amp;Norvasc-PhysicalManufacturedItem-5mgTablet">
<rdf:type rdf:resource="&idmp-sub;PhysicalManufacturedItem"/>
<rdfs:label>Norvasc, physical manufactured item, 5mg tablet</rdfs:label>
<skos:definition>actual manufactured item that is a besylate salt of amlodipine, a long-acting long-acting calcium channel blocker (CCB), used to treat high blood pressure (hypertension) and a type of chest pain called angina</skos:definition>
<idmp-mprd:isProducedAtManufacturingSite rdf:resource="&idmp-amp;PGSKalamazooManufacturingSite"/>
<idmp-mprd:isProducedByManufacturingOperation rdf:resource="&idmp-amp;PGSKalamazooOperation"/>
<cmns-doc:isSpecifiedIn rdf:resource="&idmp-amp;Norvasc-ManufacturedItem-5mgTablet"/>
<cmns-prd:isProducedBy rdf:resource="&idmp-amp;PfizerLaboratoriesAsManufacturer"/>
</owl:NamedIndividual>

<owl:NamedIndividual rdf:about="&idmp-amp;Norvasc-ShelfLife">
<rdf:type rdf:resource="&idmp-mprd;ShelfLife"/>
<rdfs:label>Norvasc, ShelfLife</rdfs:label>
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<rdfs:label>Norvasc medicinal product</rdfs:label>
<dct:source rdf:resource="https://labeling.pfizer.com/showlabeling.aspx?id=562"/>
<dct:source rdf:resource="https://www.dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=abd6a2ca-40c2-485c-bc53-db1c652505ed"/>
<skos:definition>pharmaceutical and medicinal product that is a besylate salt of amlodipine, a long-acting long-acting calcium channel blocker (CCB), used to treat high blood pressure (hypertension) and a type of chest pain called angina</skos:definition>
<skos:definition>specification for a pharmaceutical and medicinal product that is a besylate salt of amlodipine, a long-acting long-acting calcium channel blocker (CCB), used to treat high blood pressure (hypertension) and a type of chest pain called angina</skos:definition>
<skos:note>Norvasc (amlodipine besylate) Tablets are formulated as white tablets equivalent to 2.5, 5, and 10 mg of amlodipine for oral administration. In addition to the active ingredient, amlodipine besylate, each tablet contains the following inactive ingredients: microcrystalline cellulose, dibasic calcium phosphate anhydrous, sodium starch glycolate, and magnesium stearate.</skos:note>
<idmp-mprd:hasShelfLife rdf:resource="&idmp-amp;Norvasc-ShelfLife"/>
<idmp-mprd:isProducedAtManufacturingSite rdf:resource="&idmp-amp;PGSKalamazooManufacturingSite"/>
<idmp-mprd:isProducedByManufacturingOperation rdf:resource="&idmp-amp;PGSKalamazooOperation"/>
<cmns-col:comprises rdf:resource="&idmp-amp;Norvasc-ManufacturedItem-5mgTablet"/>
<cmns-col:comprises rdf:resource="&idmp-amp;Norvasc-PharmaceuticalProduct"/>
<cmns-doc:specifies rdf:resource="&idmp-amp;NorvascPhysicalMedicinalProduct"/>
<cmns-id:isIdentifiedBy rdf:resource="&idmp-amp;NorvascMedicinalProductIdentifier"/>
<cmns-prd:isProducedBy rdf:resource="&idmp-amp;PfizerLaboratoriesAsManufacturer"/>
</owl:NamedIndividual>
Expand Down Expand Up @@ -1381,6 +1397,21 @@
<cmns-prd:isProducedBy rdf:resource="&idmp-amp;PfizerLaboratoriesAsManufacturer"/>
</owl:NamedIndividual>

<owl:NamedIndividual rdf:about="&idmp-amp;NorvascPhysicalMedicinalProduct">
<rdf:type rdf:resource="&idmp-mprd;PhysicalMedicinalProduct"/>
<rdfs:label>Norvasc physical medicinal product</rdfs:label>
<dct:source rdf:resource="https://labeling.pfizer.com/showlabeling.aspx?id=562"/>
<dct:source rdf:resource="https://www.dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=abd6a2ca-40c2-485c-bc53-db1c652505ed"/>
<skos:definition>actual pharmaceutical and medicinal product that is a besylate salt of amlodipine, a long-acting long-acting calcium channel blocker (CCB), used to treat high blood pressure (hypertension) and a type of chest pain called angina</skos:definition>
<skos:note>Norvasc (amlodipine besylate) Tablets are formulated as white tablets equivalent to 2.5, 5, and 10 mg of amlodipine for oral administration. In addition to the active ingredient, amlodipine besylate, each tablet contains the following inactive ingredients: microcrystalline cellulose, dibasic calcium phosphate anhydrous, sodium starch glycolate, and magnesium stearate.</skos:note>
<idmp-mprd:hasShelfLife rdf:resource="&idmp-amp;Norvasc-ShelfLife"/>
<idmp-mprd:hasSpecifiedIdentifier rdf:resource="&idmp-amp;NorvascMedicinalProductIdentifier"/>
<idmp-mprd:isProducedAtManufacturingSite rdf:resource="&idmp-amp;PGSKalamazooManufacturingSite"/>
<idmp-mprd:isProducedByManufacturingOperation rdf:resource="&idmp-amp;PGSKalamazooOperation"/>
<cmns-doc:isSpecifiedIn rdf:resource="&idmp-amp;NorvascMedicinalProduct"/>
<cmns-prd:isProducedBy rdf:resource="&idmp-amp;PfizerLaboratoriesAsManufacturer"/>
</owl:NamedIndividual>

<owl:NamedIndividual rdf:about="&idmp-amp;NorvascTherapeuticIndicationTextInDenmark">
<rdf:type rdf:resource="&idmp-mprd;TherapeuticIndicationText"/>
<rdfs:label>Norvasc, Therapeutic Indication Text, Denmark</rdfs:label>
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