diff --git a/.meta.toml b/.meta.toml
index da6b5b9..46cf128 100644
--- a/.meta.toml
+++ b/.meta.toml
@@ -31,7 +31,6 @@ testenv-deps = [
     "# universal2 mode instead of architecture-specific. These dependencies",
     "# must be installed separately, zc.buildout is incompatible with the",
     "# universal2 mode and cannot install them itself.",
-    "universal2: -c {toxinidir}/constraints.txt",
     "universal2: zope.interface",
     "universal2: zope.security",
     "universal2: zope.container",
diff --git a/tox.ini b/tox.ini
index eb3d518..c297298 100644
--- a/tox.ini
+++ b/tox.ini
@@ -22,7 +22,6 @@ deps =
     # universal2 mode instead of architecture-specific. These dependencies
     # must be installed separately, zc.buildout is incompatible with the
     # universal2 mode and cannot install them itself.
-    universal2: -c {toxinidir}/constraints.txt
     universal2: zope.interface
     universal2: zope.security
     universal2: zope.container