diff --git a/CHANGELOG.md b/CHANGELOG.md
index 10563a9d1c..e26138d163 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -19,6 +19,7 @@ This component adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0.h
 - Following packages updated
   - `MongoDB.Driver.Core.Extensions.DiagnosticSources` from `1.3.0` to `1.4.0`.
 - .NET Framework only, following packages updated
+  - `Google.Protobuf` updated from `3.25.2` to `3.25.3`,
   - `Grpc.Core.Api` from `2.60.0` to `2.61.0`,
   - `Microsoft.Extensions.Options` from `8.0.1` to `8.0.2`,
   - `System.Text.Json` from `8.0.1` to `8.0.2`.
diff --git a/build/LibraryVersions.g.cs b/build/LibraryVersions.g.cs
index a0655e465a..cac0d9ce59 100644
--- a/build/LibraryVersions.g.cs
+++ b/build/LibraryVersions.g.cs
@@ -81,7 +81,7 @@ public static class LibraryVersion
                 new("2.1.7"),
                 new("3.1.5"),
                 new("4.0.5"),
-                new("5.1.5"),
+                new("5.2.0"),
             }
         },
         {
@@ -96,7 +96,7 @@ public static class LibraryVersion
             new List<PackageBuildInfo>
             {
                 new("2.19.0"),
-                new("2.23.1"),
+                new("2.24.0"),
             }
         },
         {
diff --git a/examples/demo/Service/Directory.Packages.props b/examples/demo/Service/Directory.Packages.props
index 4508a7da80..3ce7921854 100644
--- a/examples/demo/Service/Directory.Packages.props
+++ b/examples/demo/Service/Directory.Packages.props
@@ -3,7 +3,7 @@
     <ManagePackageVersionsCentrally>true</ManagePackageVersionsCentrally>
   </PropertyGroup>
   <ItemGroup>
-    <PackageVersion Include="Microsoft.Data.SqlClient" Version="5.1.5" />
+    <PackageVersion Include="Microsoft.Data.SqlClient" Version="5.2.0" />
     <PackageVersion Include="Microsoft.Extensions.Logging" Version="8.0.0" />
   </ItemGroup>
 </Project>
diff --git a/src/Directory.Packages.props b/src/Directory.Packages.props
index f16aa8fbb5..24179920bd 100644
--- a/src/Directory.Packages.props
+++ b/src/Directory.Packages.props
@@ -62,7 +62,7 @@
     <PackageVersion Include="System.Windows.Extensions" Version="4.7.0" />
   </ItemGroup>
   <ItemGroup Label="Transient dependencies auto-generated by GenerateNetFxTransientDependencies">
-    <PackageVersion Include="Google.Protobuf" Version="3.25.2" />
+    <PackageVersion Include="Google.Protobuf" Version="3.25.3" />
     <PackageVersion Include="Grpc" Version="2.46.6" />
     <PackageVersion Include="Grpc.Core" Version="2.46.6" />
     <PackageVersion Include="Grpc.Core.Api" Version="2.61.0" />
diff --git a/src/OpenTelemetry.AutoInstrumentation.Native/netfx_assembly_redirection.h b/src/OpenTelemetry.AutoInstrumentation.Native/netfx_assembly_redirection.h
index 72db15b167..4d276d0529 100644
--- a/src/OpenTelemetry.AutoInstrumentation.Native/netfx_assembly_redirection.h
+++ b/src/OpenTelemetry.AutoInstrumentation.Native/netfx_assembly_redirection.h
@@ -18,7 +18,7 @@ void CorProfiler::InitNetFxAssemblyRedirectsMap()
     const USHORT auto_major = atoi(AUTO_MAJOR);
 
     assembly_version_redirect_map_.insert({
-        { L"Google.Protobuf", {3, 25, 2, 0} },
+        { L"Google.Protobuf", {3, 25, 3, 0} },
         { L"Grpc.Core", {2, 0, 0, 0} },
         { L"Grpc.Core.Api", {2, 0, 0, 0} },
         { L"Microsoft.Bcl.AsyncInterfaces", {8, 0, 0, 0} },
diff --git a/test/Directory.Packages.props b/test/Directory.Packages.props
index 39c231bce9..23385a90c5 100644
--- a/test/Directory.Packages.props
+++ b/test/Directory.Packages.props
@@ -5,7 +5,7 @@
     <PackageVersion Include="Elastic.Clients.Elasticsearch" Version="8.12.0" />
     <PackageVersion Include="Confluent.Kafka" Version="2.3.0" />
     <PackageVersion Include="FluentAssertions" Version="6.12.0" />
-    <PackageVersion Include="Google.Protobuf" Version="3.25.2" />
+    <PackageVersion Include="Google.Protobuf" Version="3.25.3" />
     <PackageVersion Include="GraphQL" Version="7.8.0" />
     <PackageVersion Include="GraphQL.MicrosoftDI" Version="7.8.0" />
     <PackageVersion Include="GraphQL.Server.Transports.AspNetCore" Version="7.7.1" />
@@ -20,7 +20,7 @@
     <PackageVersion Include="Microsoft.AspNetCore.SignalR.Client" Version="8.0.1" />
     <PackageVersion Include="Microsoft.Build" Version="15.9.20" />
     <PackageVersion Include="Microsoft.Build.Utilities.Core" Version="15.9.20" />
-    <PackageVersion Include="Microsoft.Data.SqlClient" Version="5.1.5" />
+    <PackageVersion Include="Microsoft.Data.SqlClient" Version="5.2.0" />
     <PackageVersion Include="Microsoft.EntityFrameworkCore.Sqlite" Version="8.0.2" />
     <PackageVersion Include="Microsoft.Extensions.Configuration.Abstractions" Version="8.0.0" />
     <PackageVersion Include="Microsoft.Extensions.DependencyInjection" Version="8.0.0" />
@@ -28,7 +28,7 @@
     <PackageVersion Include="Microsoft.Extensions.Hosting" Version="8.0.0" />
     <PackageVersion Include="Microsoft.Extensions.Logging" Version="8.0.0" />
     <PackageVersion Include="Microsoft.NET.Test.Sdk" Version="17.9.0" />
-    <PackageVersion Include="MongoDB.Driver" Version="2.23.1" />
+    <PackageVersion Include="MongoDB.Driver" Version="2.24.0" />
     <PackageVersion Include="NSubstitute" Version="5.1.0" />
     <PackageVersion Include="MySqlConnector" Version="2.3.5" />
     <PackageVersion Include="MySql.Data" Version="8.3.0" />
diff --git a/test/IntegrationTests/LibraryVersions.g.cs b/test/IntegrationTests/LibraryVersions.g.cs
index c4c8aa6986..4ebfd9de6f 100644
--- a/test/IntegrationTests/LibraryVersions.g.cs
+++ b/test/IntegrationTests/LibraryVersions.g.cs
@@ -91,7 +91,7 @@ public static class LibraryVersion
         new object[] { "2.1.7" },
         new object[] { "3.1.5" },
         new object[] { "4.0.5" },
-        new object[] { "5.1.5" },
+        new object[] { "5.2.0" },
 #endif
     };
     public static readonly IReadOnlyCollection<object[]> SqlClientSystem = new List<object[]>
@@ -108,7 +108,7 @@ public static class LibraryVersion
         new object[] { string.Empty }
 #else
         new object[] { "2.19.0" },
-        new object[] { "2.23.1" },
+        new object[] { "2.24.0" },
 #endif
     };
     public static readonly IReadOnlyCollection<object[]> MySqlConnector = new List<object[]>