[Text and logical def] conjunctiva goblet cell

[Caroline-99]

CL term
conjunctiva goblet cell

Suggested revision of textual definition

A goblet cell that is part of the conjunctival epithelium, characterized by apical accumulation of mucin granules, primarily MUC5AC in humans and Muc5ac/Muc5b in mice. These gel-forming mucins are essential for tear film stability, ocular lubrication, and pathogen defence. This cell forms tight junctions with neighbouring epithelial cells via species-specific claudins (claudin-2 in mice, claudin-10 in humans). The transcription factor SPDEF is essential for its differentiation.

PMID: 27091323
PMID: 31734511
https://iovs.arvojournals.org/article.aspx?articleid=2353928 ?

LLM R1 perplexity model output using a prompt:

Suggested revision of logical definition
goblet cell and part of some epithelium of conjunctiva