[NTR] Schlem's canal endothelial cell

[dosumis]

Please check that the term does not already exist by using the ontology search tool OLS:
https://www.ebi.ac.uk/ols4/ontologies/cl

Preferred term label
Schlem's canal endothelial cell

Synonym(s) (add reference(s), please)

Definition (free text, with reference(s), please. PubMed ID format is PMID:XXXXXX)

A specialised endothelial cell of the canal of Schlem. This cell type share characteristics of both blood and lymphatic endothelial cell 234. The inner wall endothelial cells of SC form "giant vacuoles" and transcellular pores that facilitate the passage of aqueous humor into collector channels which are critical for maintaining proper intraocular pressure 7. They regulate of aqueous humor outflow resistance by modulating pore formation and responding to mechanical strain.

Parent cell type term (check the hierarchy here https://www.ebi.ac.uk/ols4/ontologies/cl)

endothelial cell

Anatomical structure where the cell type is found (check Uberon for anatomical structures: https://www.ebi.ac.uk/ols4/ontologies/uberon)

http://purl.obolibrary.org/obo/UBERON_0004029 canal of Schlem

Your ORCID

Additional notes or concerns If there are markers that uniquely identify the cell type in a particular species, they can be added here.

Def adapted from https://www.perplexity.ai/search/are-the-endothelial-cells-of-s-niggOTOzSiCWHHDGST62IQ
Refs need checking!

Also curious about whether we need separate subtype for inner wall cells as these feature giant vacuoles. With that, the vacuoles and transcellular pores can be added as cell components.

Open access figures: https://www.mdpi.com/2079-4983/6/3/963.

Needed for Needed for: https://celltype.info/project/562