From 402e5d816042c89252b7428e966f0d946fc9475b Mon Sep 17 00:00:00 2001 From: bvarner-ebi <95643797+bvarner-ebi@users.noreply.github.com> Date: Tue, 21 Mar 2023 13:42:38 +0000 Subject: [PATCH] release-2023-03-21b status post PR #1903 merge. --- cl-base.owl | 4242 +- cl.obo | 23379 ++----- patterns/definitions.owl | 7 +- src/ontology/diffs/cl-diff.md | 53124 +++++++++++++++- .../reports/cl-edit.owl-obo-report.tsv | 15 +- 5 files changed, 57006 insertions(+), 23761 deletions(-) diff --git a/cl-base.owl b/cl-base.owl index 9a6067ac7..088c69873 100644 --- a/cl-base.owl +++ b/cl-base.owl @@ -17,7 +17,7 @@ xmlns:ubprop="http://purl.obolibrary.org/obo/ubprop#" xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"> - + An ontology of cell types. Cell Ontology @@ -33,7 +33,7 @@ See PMID:15693950, PMID:12799354, PMID:20123131, PMID:21208450; Contact Alexander Diehl, addiehl@buffalo.edu, University at Buffalo. - 2023-02-19 + 2023-03-21 @@ -445,6 +445,32 @@ + + + + has_not_completed + + + + + + + + http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y + lacks_part + + + + + + + + http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y) + lacks_plasma_membrane_part + + + + @@ -565,6 +591,12 @@ + + + + + + @@ -595,6 +627,12 @@ + + + + + + @@ -661,38 +699,6 @@ - - - - has_not_completed - - - - - - - - http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y - lacks_part - - - - - - - - http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y) - lacks_plasma_membrane_part - - - - - - - - - - @@ -713,6 +719,7 @@ + @@ -918,7 +925,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u Obsolete. Use PO:0000079 from Plant Ontology instead. An elongated cell with approximately wedge-shaped ends, found in the vascular cambium, which gives rise to the elements of the axial system in the secondary vascular tissues. - CL:0000274 xylem initial xylem mother cell obsolete fusiform initial @@ -1593,7 +1599,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u A cell that will develop into a neuron often after a migration phase. - CL:0000337 BTO:0000930 FMA:70563 neuroblast @@ -1753,61 +1758,61 @@ Covers cells actively being cultured or stored in a quiescent state for future u - - - - - - - - - + - + - + - + - + - + - + - + - + - + - + - + + + + + + + + + @@ -2209,7 +2214,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. - CL:0000739 polymorphonuclear leucocyte polymorphonuclear leukocyte BTO:0001026 @@ -2499,7 +2503,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u A oligopotent progenitor cell committed to the lymphoid lineage. - CL:0000044 CLP common lymphocyte precursor common lymphocyte progenitor @@ -2721,8 +2724,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u Skeletogenic cell that produces enamel, overlies the odontogenic papilla, and arises from the differentiation of a preameloblast cell. - CL:0000053 - CL:0000139 BTO:0001663 FMA:70576 amelocyte @@ -2807,7 +2808,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u Skeletogenic cell that produces cementum (a bony substance that covers the root of a tooth), is part of the odontogenic papilla, and develops from a precementoblast cell. - CL:0000859 CALOHA:TS-1164 FMA:63002 cementum secreting cell @@ -3377,8 +3377,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. - CL:0000804 - CL:0000812 BTO:0000782 CALOHA:TS-1001 FMA:62870 @@ -3668,36 +3666,36 @@ Covers cells actively being cultured or stored in a quiescent state for future u - - + + - - + + - - + + - - + + - - + + - - + + - - + + - - + + @@ -3777,6 +3775,18 @@ Covers cells actively being cultured or stored in a quiescent state for future u + + + + + + + + + + + + @@ -3821,18 +3831,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - - - - - - - - - - - - @@ -3889,6 +3887,10 @@ Covers cells actively being cultured or stored in a quiescent state for future u + + + + @@ -3929,10 +3931,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u - - - - @@ -4872,16 +4870,21 @@ Covers cells actively being cultured or stored in a quiescent state for future u - - + + + + + + + - Cell of the single layer of large flattened cells covering the surface of the cornea. + An hexagonal, flattened, mitochondria-rich endothelial cell that forms a monolayer on the posterior surface of the cornea (the corneal endothelium). Corneal endothelial cells are derived from the neural crest and are responsible for keeping the cornea transparent by maintaining the tissue in a semi-dry state through the action of their ionic pumps and tight junction barrier. CALOHA:TS-0172 FMA:70614 @@ -4891,9 +4894,13 @@ Covers cells actively being cultured or stored in a quiescent state for future u - Cell of the single layer of large flattened cells covering the surface of the cornea. + An hexagonal, flattened, mitochondria-rich endothelial cell that forms a monolayer on the posterior surface of the cornea (the corneal endothelium). Corneal endothelial cells are derived from the neural crest and are responsible for keeping the cornea transparent by maintaining the tissue in a semi-dry state through the action of their ionic pumps and tight junction barrier. GOC:tfm MESH:A09.371.060.067.31 + PMID:21976958 + PMID:23284695 + PMID:34741068 + PMID:36769303 @@ -4922,7 +4929,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. - CL:0002452 BTO:0002625 BTO:0003298 FMA:70546 @@ -5065,7 +5071,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides. - CL:0000450 BTO:0000443 CALOHA:TS-0012 FMA:63880 @@ -5360,7 +5365,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance. - CL:0000572 BTO:0000847 CALOHA:TS-0613 FMA:70545 @@ -5731,10 +5735,20 @@ Covers cells actively being cultured or stored in a quiescent state for future u - + - + + + + + + + + + + + @@ -5742,7 +5756,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - + A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions. @@ -5802,7 +5816,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u A neuron that is capable of some hormone secretion in response to neuronal signals. - CL:0000381 BTO:0002691 FMA:83810 FBbt:00005130 @@ -6652,7 +6665,6 @@ The modern definition of neurosecretion has evolved to include the release of an A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast). - CL:0000191 non-striated muscle cell BTO:0004576 CALOHA:TS-2159 @@ -6701,7 +6713,6 @@ The modern definition of neurosecretion has evolved to include the release of an A striated muscle cell of an arthropod heart that participates in heart contraction. - CL:0000466 cardiac muscle cell (sensu Arthopoda) @@ -6879,7 +6890,6 @@ The modern definition of neurosecretion has evolved to include the release of an A mechanoreceptor cell of the auditory or vestibular system that is sensitive to auditory stimuli. The accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system. - CL:0000201 FMA:62364 auditory receptor cell In mammals these cells are located in the organ of Corti. @@ -7548,6 +7558,14 @@ The modern definition of neurosecretion has evolved to include the release of an + + + + + + + + @@ -7560,14 +7578,6 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - - - - - @@ -8003,20 +8013,20 @@ The modern definition of neurosecretion has evolved to include the release of an - - Type of neuron that is a primary mechanosensory cell, with peripheral neurites innervating the skin with free nerve endings. + + RB neuron VHOG:0001484 - - Rohon Beard cell + + Type of neuron that is a primary mechanosensory cell, with peripheral neurites innervating the skin with free nerve endings. VHOG:0001484 - - RB neuron + + Rohon Beard cell VHOG:0001484 @@ -8709,7 +8719,6 @@ The modern definition of neurosecretion has evolved to include the release of an A peptide hormone secreting cell that produces growth hormone, somatotropin. - CL:0000471 growth hormone secreting cell somatotrophin secreting cell somatotropin secreting cell @@ -8922,7 +8931,6 @@ The modern definition of neurosecretion has evolved to include the release of an An epithelial cell found in the trachea. - CL:1000474 FMA:74793 FBbt:00005038 tracheocyte @@ -9017,7 +9025,6 @@ The modern definition of neurosecretion has evolved to include the release of an An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. - CL:0002185 BTO:0000667 CALOHA:TS-0500 FMA:62879 @@ -9482,7 +9489,6 @@ The modern definition of neurosecretion has evolved to include the release of an A cell found within the adrenal medulla that secrete biogenic amine hormones upon stimulation. - CL:1000422 FMA:69262 medullary chromaffin cell of adrenal gland adrenal medulla chromaffin cell @@ -10089,7 +10095,6 @@ The modern definition of neurosecretion has evolved to include the release of an An epithelial cell of the integument (the outer layer of an organism). - CL:1000396 BTO:0001470 CALOHA:TS-0283 FMA:62411 @@ -10479,18 +10484,18 @@ The modern definition of neurosecretion has evolved to include the release of an - + FBbt:00005063 hemocyte (sensu Arthropoda) - + - + PMID:18025161 @@ -11609,44 +11614,44 @@ The modern definition of neurosecretion has evolved to include the release of an - - + + - - + + - - + + - - + + - - + + - - + + - - + + - - + + - - + + - - + + @@ -12018,7 +12023,6 @@ The modern definition of neurosecretion has evolved to include the release of an A peptide hormone secreting cell that produces adrenocorticotropin, or corticotropin. - CL:0000640 ACTH secreting cell adrenocorticotrophic hormone secreting cell corticotrophin hormone secreting cell @@ -12213,7 +12217,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -12226,14 +12230,14 @@ The modern definition of neurosecretion has evolved to include the release of an FBbt:00004904 follicle cell of egg chamber - + - + @@ -12944,6 +12948,12 @@ The modern definition of neurosecretion has evolved to include the release of an + + + + + + An epithelial cell found in the basal part of the intestinal glands (crypts of Lieberkuhn) including the appendix. Paneth cells synthesize and secrete lysozyme and cryptdins. Numerous in the deeper parts of the intestinal crypts, particularly in the duodenum, rich in zinc, contain large acidophilic granules, with irregular apical microvilli and prominent membrane-bound vacuoles containing matrix. BTO:0000993 FMA:62897 @@ -12962,6 +12972,8 @@ The modern definition of neurosecretion has evolved to include the release of an GOC:tfm ISBN:0517223651 MESH:D019879 + PMID:29184701 + PMID:32308658 @@ -13019,7 +13031,6 @@ The modern definition of neurosecretion has evolved to include the release of an A precursor cell destined to differentiate into cardiac muscle cell. - CL:0000714 FMA:84797 cardiac muscle progenitor cell cardiomyocyte progenitor cell @@ -13696,6 +13707,10 @@ The modern definition of neurosecretion has evolved to include the release of an + + + + @@ -13704,10 +13719,6 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - @@ -13780,17 +13791,17 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - - + - + + + + + @@ -13865,57 +13876,57 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - - - - - - + - + - + - + - + - + - + - + - + - + - + + + + + + + + + @@ -14241,61 +14252,61 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - - - - - - + - + - + - + - + - + - + - + - + - + - + - + + + + + + + + + @@ -14396,22 +14407,13 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - - - - - - - - - - - - + + + + + + @@ -14419,7 +14421,7 @@ The modern definition of neurosecretion has evolved to include the release of an - A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm. + A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release. BTO:0000843 CALOHA:TS-0611 @@ -14440,9 +14442,10 @@ The modern definition of neurosecretion has evolved to include the release of an - A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm. + A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release. ISBN:0721601464 MESH:D008533 + PMID:31043076 http://en.wikipedia.org/wiki/Megakaryocyte @@ -14467,6 +14470,14 @@ The modern definition of neurosecretion has evolved to include the release of an + + + + + + + + @@ -14479,14 +14490,6 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - - - - - @@ -14582,57 +14585,57 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - - - - - - + - + - + - + - + - + - + - + - + - + - + + + + + + + + + @@ -14744,32 +14747,32 @@ The modern definition of neurosecretion has evolved to include the release of an - - + + - - + + - - + + - - + + - - + + - - + + - - + + @@ -14942,12 +14945,12 @@ The modern definition of neurosecretion has evolved to include the release of an - - + + - - + + @@ -15306,7 +15309,6 @@ The modern definition of neurosecretion has evolved to include the release of an An epithelial cell of the cornea. - CL:1000431 BTO:0004298 CALOHA:TS-0173 FMA:70551 @@ -15402,7 +15404,6 @@ The modern definition of neurosecretion has evolved to include the release of an A subtype of enteroendocrine cells found in the gastrointestinal mucosa, particularly in the glands of pyloric antrum; duodenum; and ileum. These cell type secretes serotonin and some neurotransmitters including enkephalins and substance P. Their secretory granules stain readily with silver (argentaffin stain). - CL:0002065 FMA:62934 FMA:83132 Kulchitsky cell @@ -15488,6 +15489,14 @@ The modern definition of neurosecretion has evolved to include the release of an + + + + + + + + @@ -15508,14 +15517,6 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - - - - - @@ -15562,6 +15563,10 @@ The modern definition of neurosecretion has evolved to include the release of an + + + + @@ -15594,10 +15599,6 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - @@ -15676,6 +15677,10 @@ The modern definition of neurosecretion has evolved to include the release of an + + + + @@ -15700,10 +15705,6 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - @@ -15750,6 +15751,10 @@ The modern definition of neurosecretion has evolved to include the release of an + + + + @@ -15786,10 +15791,6 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - @@ -16468,77 +16469,77 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - - - - - - - - - - - - - - - - - - - - - - + - + - + - + - + - + - + - + - + - + - + - + + + + + + + + + + + + + + + + + + + + + + + + + @@ -16583,6 +16584,14 @@ The modern definition of neurosecretion has evolved to include the release of an + + + + + + + + @@ -16603,14 +16612,6 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - - - - - @@ -16660,69 +16661,69 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - - - - - - - - - - + - + - + - + - + - + - + - + - + - + - + - + - + + + + + + + + + + + + + @@ -16770,6 +16771,18 @@ The modern definition of neurosecretion has evolved to include the release of an + + + + + + + + + + + + @@ -16790,18 +16803,6 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - - - - - - - - - @@ -16998,29 +16999,29 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - - - - - - + - + - + - + + + + + + + + + @@ -17064,12 +17065,12 @@ The modern definition of neurosecretion has evolved to include the release of an - - + + - - + + @@ -17108,12 +17109,12 @@ The modern definition of neurosecretion has evolved to include the release of an - - + + - - + + @@ -17741,7 +17742,6 @@ The modern definition of neurosecretion has evolved to include the release of an A smooth muscle cell that synthesizes, stores, and secretes the enzyme renin. This cell type are located in the wall of the afferent arteriole at the entrance to the glomerulus. While having a different origin than other kidney smooth muscle cells, this cell type expresses smooth muscle actin upon maturation. - CL:0000461 juxtaglomerular cell FMA:84138 JG cell @@ -17772,7 +17772,6 @@ The modern definition of neurosecretion has evolved to include the release of an A cell with delicate radiating processes known as desmosomes that form intercellular bridges between other cells of this type. This cell type forms the stratum spinosum (prickle cell layer). A function of this cell is to generate keratin. - CL:0002186 FMA:69059 prickle cell of epidermis @@ -17934,7 +17933,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -17979,7 +17978,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -18261,7 +18260,6 @@ The modern definition of neurosecretion has evolved to include the release of an An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. - CL:0000184 BTO:0002441 FMA:63174 ARC @@ -19070,7 +19068,6 @@ radial glial cells acting as neural progenitors throughout life. Specialized ependymal cell that produces the cerebrospinal fluid from the blood and secretes it into the lumen of the brain and spinal chord. - CL:1000430 FMA:70549 epithelial cell of choroid plexus choroid plexus epithelial cell @@ -20110,7 +20107,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -20128,7 +20125,7 @@ radial glial cells acting as neural progenitors throughout life. FMB cone bipolar cell type 2 cone bipolar cell (sensu Mus) - + @@ -20148,7 +20145,7 @@ radial glial cells acting as neural progenitors throughout life. - + PMID:27565351 @@ -20478,7 +20475,6 @@ radial glial cells acting as neural progenitors throughout life. A immature or mature cell in the lineage leading to and including erythrocytes. - CL:0002156 CALOHA:TS-0290 FMA:62845 FMA:83516 @@ -20509,57 +20505,57 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + - + - + - + - + - + - + - + - + - + - + + + + + @@ -21426,12 +21422,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -21628,21 +21624,21 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + - + + + + + @@ -21699,6 +21695,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -21711,10 +21711,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -21757,6 +21753,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -21769,14 +21773,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -21867,7 +21863,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -22312,11 +22308,11 @@ radial glial cells acting as neural progenitors throughout life. - + - + @@ -22490,11 +22486,11 @@ radial glial cells acting as neural progenitors throughout life. - + - + @@ -22544,28 +22540,28 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + - - + + - - + + @@ -22613,20 +22609,20 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + @@ -22670,24 +22666,24 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + - - + + @@ -22732,25 +22728,25 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + - + - + + + + + @@ -22853,12 +22849,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -22907,12 +22903,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -23128,20 +23124,20 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + @@ -23193,12 +23189,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -23237,6 +23233,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -23253,10 +23253,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -23423,7 +23419,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -23465,12 +23461,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -23604,6 +23600,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -23620,14 +23624,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -23953,93 +23949,93 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - - - - - - - - - - - - - - - - - + - + - + - + - + - + - + - + - + - + - + - + - + - + - + - + + + + + + + + + + + + + + + + + + + + + + + + + @@ -24222,7 +24218,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -24282,24 +24278,24 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + - - + + @@ -24339,65 +24335,65 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - + - + - + - + - + - + - + - + - + - + - + - + - + + + + + + + + + @@ -24676,6 +24672,18 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + + + + + @@ -24696,18 +24704,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - - - - @@ -24810,6 +24806,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -24826,14 +24830,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -24972,7 +24968,6 @@ radial glial cells acting as neural progenitors throughout life. A neuron that releases serotonin as a neurotransmitter. - CL:0000403 MESH:D059326 WBbt:0006837 FBbt:00005133 @@ -25208,6 +25203,18 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + + + + + @@ -25224,18 +25231,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - - - - @@ -25735,6 +25730,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -25751,10 +25750,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -25793,6 +25788,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -25805,10 +25804,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -25845,6 +25840,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -25877,10 +25876,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -25915,6 +25910,18 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + + + + + @@ -25931,18 +25938,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - - - - @@ -25993,12 +25988,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -26669,7 +26664,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -26719,21 +26714,21 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + - + + + + + @@ -26778,6 +26773,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -26798,10 +26797,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -26864,20 +26859,20 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + @@ -27027,6 +27022,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -27035,10 +27034,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -27099,6 +27094,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -27119,10 +27118,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -27338,17 +27333,17 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + + + + + @@ -27397,15 +27392,15 @@ radial glial cells acting as neural progenitors throughout life. - + - + - + @@ -27459,24 +27454,24 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + - - + + @@ -27520,17 +27515,17 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + + + + + @@ -27580,6 +27575,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -27596,14 +27599,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -27824,15 +27819,15 @@ radial glial cells acting as neural progenitors throughout life. - + - + - + @@ -27936,17 +27931,17 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + + + + + @@ -28050,6 +28045,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -28058,10 +28057,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -28119,17 +28114,17 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + + + + + @@ -28236,7 +28231,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -28419,11 +28414,11 @@ radial glial cells acting as neural progenitors throughout life. - + - + @@ -28639,20 +28634,20 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + @@ -28698,20 +28693,20 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + @@ -28758,20 +28753,20 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + @@ -29018,11 +29013,11 @@ radial glial cells acting as neural progenitors throughout life. - + - + @@ -29062,6 +29057,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -29078,14 +29081,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -29179,6 +29174,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -29195,14 +29198,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -29243,6 +29238,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -29263,10 +29262,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -29363,17 +29358,17 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + + + + + @@ -29413,6 +29408,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -29421,10 +29420,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -29842,6 +29837,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -29854,10 +29853,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -29891,19 +29886,19 @@ radial glial cells acting as neural progenitors throughout life. - + - + - + - + @@ -29947,17 +29942,17 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + + + + + @@ -29996,17 +29991,17 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + + + + + @@ -30132,17 +30127,17 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + + + + + @@ -30187,25 +30182,25 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + - + - + + + + + @@ -30245,6 +30240,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -30265,10 +30264,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -30390,17 +30385,17 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + + + + + @@ -30501,6 +30496,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -30509,10 +30508,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -30555,6 +30550,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -30567,10 +30566,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -30618,6 +30613,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -30630,10 +30629,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -30685,20 +30680,20 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + @@ -30750,6 +30745,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -30758,10 +30757,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -30917,32 +30912,32 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + - - + + - - + + - - + + @@ -31006,12 +31001,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -31048,6 +31043,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -31056,10 +31055,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -31152,32 +31147,32 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + - - + + - - + + - - + + @@ -31406,6 +31401,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -31418,14 +31421,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -31472,11 +31467,11 @@ radial glial cells acting as neural progenitors throughout life. - + - + @@ -31749,6 +31744,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -31761,10 +31760,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -32004,6 +31999,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -32016,10 +32015,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -32185,24 +32180,24 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + - - + + @@ -32245,6 +32240,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -32257,14 +32260,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -32299,6 +32294,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -32319,14 +32322,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -32740,49 +32735,49 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - - - - - + - + - + - + - + - + - + - + + + + + + + + + + + + + @@ -33461,6 +33456,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -33473,14 +33476,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -33526,40 +33521,40 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + - - + + - - + + - - + + - - + + - - + + @@ -33608,6 +33603,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -33632,10 +33631,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -33681,29 +33676,29 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - + - + - + - + + + + + + + + + @@ -33740,17 +33735,17 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + + + + + @@ -33790,6 +33785,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -33798,10 +33797,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -33844,65 +33839,65 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - - - - - + - + - + - + - + - + - + - + - + - + - + - + + + + + + + + + + + + + @@ -34308,6 +34303,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -34320,14 +34323,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -34364,12 +34359,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -34574,6 +34569,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -34586,14 +34589,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -34632,11 +34627,11 @@ radial glial cells acting as neural progenitors throughout life. - + - + @@ -34675,11 +34670,11 @@ radial glial cells acting as neural progenitors throughout life. - + - + @@ -34718,7 +34713,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -34754,21 +34749,21 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + - + + + + + @@ -34913,6 +34908,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -34921,10 +34920,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -35069,57 +35064,57 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + - + - + - + - + - + - + - + - + - + - + + + + + @@ -35186,6 +35181,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -35198,14 +35201,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -35334,20 +35329,20 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + @@ -35379,57 +35374,57 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - + - + - + - + - + - + - + - + - + - + - + + + + + + + + + @@ -35619,6 +35614,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -35631,10 +35630,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -35922,6 +35917,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -35930,10 +35929,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -36034,6 +36029,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -36046,14 +36049,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -36114,6 +36109,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -36122,10 +36121,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -36223,6 +36218,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -36247,10 +36246,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -36293,6 +36288,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -36317,10 +36316,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -36375,37 +36370,37 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - + - + - + - + - + - + + + + + + + + + @@ -36501,36 +36496,36 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + - - + + - - + + - - + + - - + + @@ -36576,12 +36571,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -36625,11 +36620,11 @@ radial glial cells acting as neural progenitors throughout life. - + - + @@ -36673,20 +36668,20 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + @@ -36723,33 +36718,33 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - + - + - + - + - + + + + + + + + + @@ -36785,6 +36780,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -36797,10 +36796,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -36939,69 +36934,69 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - - - - - + - + - + - + - + - + - + - + - + - + - + - + - + + + + + + + + + + + + + @@ -37094,6 +37089,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -37106,14 +37109,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -37155,12 +37150,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -37203,21 +37198,21 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + - + + + + + @@ -37259,21 +37254,21 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + - + + + + + @@ -37363,24 +37358,24 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + - - + + @@ -37423,12 +37418,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -37698,6 +37693,18 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + + + + + @@ -37714,18 +37721,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - - - - @@ -37766,6 +37761,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -37774,10 +37773,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -37818,6 +37813,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -37826,10 +37825,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -37928,6 +37923,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -37940,14 +37943,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -37990,6 +37985,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -38006,10 +38005,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -38049,20 +38044,20 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + @@ -38192,6 +38187,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -38200,10 +38199,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -38247,20 +38242,20 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + @@ -38299,20 +38294,20 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + @@ -38461,6 +38456,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -38481,10 +38480,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -38579,6 +38574,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -38591,14 +38594,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -38638,17 +38633,17 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + + + + + @@ -38690,6 +38685,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -38702,10 +38701,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -38744,6 +38739,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -38756,10 +38755,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -38803,21 +38798,21 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + - + + + + + @@ -38858,6 +38853,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -38870,14 +38873,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -38911,6 +38906,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -38931,14 +38934,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -38977,6 +38972,18 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + + + + + @@ -39001,18 +39008,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - - - - @@ -39047,6 +39042,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -39055,10 +39054,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -39165,6 +39160,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -39185,10 +39184,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -39340,6 +39335,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -39368,14 +39371,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -39475,6 +39470,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -39491,14 +39494,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -39541,6 +39536,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -39553,10 +39552,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -39596,6 +39591,18 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + + + + + @@ -39616,18 +39623,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - - - - @@ -39666,6 +39661,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -39678,10 +39677,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -39727,6 +39722,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -39751,10 +39750,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -40675,7 +40670,6 @@ radial glial cells acting as neural progenitors throughout life. Specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS. Resemble spongioblasts seen in developing brain. Found in the adult brain in the third ventricle, cerebral aqueduct, spinal canal and floor of the fourth ventricle. 2010-07-15T11:21:11Z - CL:0000643 BTO:0001953 FMA:54560 stretch cell @@ -40719,7 +40713,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -40806,77 +40800,77 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - - - - - - - - - - - - - - - - - - - - - + - + - + - + - + - + - + - + - + - + - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -41190,7 +41184,6 @@ radial glial cells acting as neural progenitors throughout life. A small, polyhedral, cell found in rounded groups or curved columns with deeply staining nuclei, scanty basophilic cytoplasm and a few lipid droplets. This cell in the zona glomerulosa produces mineralocorticoids. 2010-08-24T01:42:02Z - CL:1000423 FMA:69273 epithelial cell of zona glomerulosa of adrenal gland type I cell of adrenal cortex @@ -41281,7 +41274,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -41375,7 +41368,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -41505,7 +41498,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -41541,11 +41534,11 @@ radial glial cells acting as neural progenitors throughout life. - + - + @@ -41664,7 +41657,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -41894,7 +41887,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -41937,7 +41930,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -42045,7 +42038,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -42209,6 +42202,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -42217,10 +42214,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -42367,6 +42360,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -42379,10 +42376,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -42684,7 +42677,6 @@ radial glial cells acting as neural progenitors throughout life. 2010-08-24T02:05:28Z - CL:1000421 BTO:0004167 FMA:68458 LEC @@ -42754,7 +42746,6 @@ radial glial cells acting as neural progenitors throughout life. A sebum secreting cell of the skin that secretes sebum into the hair follicles. 2010-08-24T09:27:52Z - CL:0002587 sebocyte BTO:0004613 FMA:70953 @@ -43008,7 +42999,6 @@ radial glial cells acting as neural progenitors throughout life. An epithelial cell of the uterus. 2010-08-24T10:45:54Z - CL:1000294 FMA:256161 epithelial cell of uterus @@ -43487,7 +43477,6 @@ radial glial cells acting as neural progenitors throughout life. An epithelial cell located on the basal lamina of the olfactory epithelium. 2010-08-26T01:58:54Z - CL:1000395 horizontal basal cell FMA:62303 basal cell of olfactory epithelium @@ -43766,7 +43755,6 @@ radial glial cells acting as neural progenitors throughout life. An epithelial cell found in the lining of the stomach. 2010-08-25T03:22:08Z - CL:1000399 FMA:62948 epithelial cell of stomach @@ -43824,7 +43812,6 @@ radial glial cells acting as neural progenitors throughout life. A mucous cell in the epithelium of the stomach. 2010-08-25T03:38:51Z - CL:1000404 FMA:63464 mucous cell of stomach @@ -43862,7 +43849,6 @@ radial glial cells acting as neural progenitors throughout life. A neck cell that secretes mucus within the stomach. Its products are distinct histochemically from those of the surface mucous cells of stomach. 2010-08-25T03:41:30Z - CL:1000401 FMA:62954 mucus neck cell of gastric gland mucous neck cell of gastric gland @@ -43934,7 +43920,6 @@ radial glial cells acting as neural progenitors throughout life. A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit. 2010-08-25T03:57:08Z - CL:1000400 FMA:62953 stem cell of gastric gland @@ -44015,7 +44000,6 @@ radial glial cells acting as neural progenitors throughout life. A basally situated, mitotically active, columnar-shaped keratinocyte attached to the basement membrane. 2010-08-26T03:12:49Z - CL:1000439 FMA:70571 basal cell of epidermis @@ -44303,7 +44287,6 @@ radial glial cells acting as neural progenitors throughout life. Liver progenitor cells have been variously named in rodent and human studies as oval cells, hepatic progenitor cells, liver stem cells, ductular reactions, or atypical ductular cells. They were first described as oval cells in rats due to their large nuclear-to-cytoplasm ratio and oval-shaped nuclei. On the difference between 'hepatic liver stem cells' (HLSC) and 'oval cells': "... unlike a well-known hepatic progenitor cell population, known as oval cells in rodents, HLSCs do not express CK-7, CK-19, c-kit, CD133 and alpha-smooth muscle actin (α-SMA) (Gaudio et al., 2009)". 2010-08-30T02:01:49Z - CL:1000036 BTO:0004270 FMA:86576 hepatic oval cell @@ -44489,7 +44472,6 @@ radial glial cells acting as neural progenitors throughout life. An epithelial cell of the tracheobronchial tree. 2010-09-02T02:09:14Z - CL:1000407 FMA:66816 epithelial cell of tracheobronchial tree @@ -44521,7 +44503,6 @@ radial glial cells acting as neural progenitors throughout life. Brush cell found in the epithelial layer of the colon. 2010-09-02T02:20:50Z - CL:1000387 FMA:263222 brush cell of large intestine tuft cell of epithelium of large intestine @@ -44598,7 +44579,6 @@ radial glial cells acting as neural progenitors throughout life. A brush cell found in the epithelium of lobular bronchiole. 2010-09-02T02:38:34Z - CL:1000386 FMA:263220 brush cell of lobular bronchiole @@ -44628,7 +44608,6 @@ radial glial cells acting as neural progenitors throughout life. A brush cell of the epithelium in the terminal bronchiole. 2010-09-02T02:38:36Z - CL:1000390 FMA:263228 brush cell of terminal bronchiole @@ -44661,7 +44640,6 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-02T02:38:37Z - CL:1000388 FMA:263224 brush cell of trachea @@ -44705,7 +44683,6 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-02T02:38:42Z - CL:1000389 FMA:263226 brush cell of bronchus @@ -45267,8 +45244,6 @@ radial glial cells acting as neural progenitors throughout life. An epithelial cell of the prostate. 2010-09-07T01:49:29Z - CL:1000295 - CL:1000408 FMA:256163 FMA:66817 prostate epithelial cell @@ -45308,7 +45283,6 @@ radial glial cells acting as neural progenitors throughout life. An epithelial cell of prostatic duct. 2010-09-07T01:55:51Z - CL:1000462 FMA:74224 ductal epithelial cell of prostate epithelial cell of prostatic duct @@ -45352,7 +45326,6 @@ radial glial cells acting as neural progenitors throughout life. An epithelial cell of the prostatic acinus. 2010-09-07T01:55:53Z - CL:1000461 FMA:74223 acinar epithelial cell of prostate epithelial cell of prostatic acinus @@ -45396,7 +45369,6 @@ radial glial cells acting as neural progenitors throughout life. A cell of the basal layer of the epithelium in the prostatic acinus. 2010-09-07T01:59:08Z - CL:1000464 FMA:74265 basal epithelial cell of prostatic acinus basal cell of prostatic acinus @@ -45462,7 +45434,6 @@ radial glial cells acting as neural progenitors throughout life. A cell that constitutes the basal layer of epithelium in the prostatic duct. 2010-09-07T01:59:12Z - CL:1000463 FMA:74226 basal epithelial cell of prostatic duct @@ -45955,7 +45926,6 @@ radial glial cells acting as neural progenitors throughout life. An epithelial cell of the esophagus. 2010-09-08T09:28:20Z - CL:1000402 FMA:63071 epithelial cell of esophagus @@ -45992,7 +45962,6 @@ radial glial cells acting as neural progenitors throughout life. An epithelial cell of the large intestine. 2010-09-08T09:28:22Z - CL:1000292 BTO:0004297 FMA:256157 epithelial cell of colon @@ -46031,7 +46000,6 @@ radial glial cells acting as neural progenitors throughout life. An epithelial cell of the small intestine. 2010-09-08T09:41:46Z - CL:1000293 FMA:256159 epithelial cell of small intestine @@ -46155,7 +46123,6 @@ radial glial cells acting as neural progenitors throughout life. An epithelial cell of thyroid gland. 2010-09-08T01:46:51Z - CL:1000297 FMA:256167 MESH:D000072637 epithelial cell of thyroid gland @@ -46240,7 +46207,6 @@ radial glial cells acting as neural progenitors throughout life. An epithelial cell of the parathyroid gland. 2010-09-08T02:29:38Z - CL:1000429 FMA:70547 epithelial cell of parathyroid gland @@ -46266,7 +46232,6 @@ radial glial cells acting as neural progenitors throughout life. An endothelial cell found in the mucosa associated with the facial skeleton. 2010-09-14T10:40:12Z - CL:1000446 FMA:70627 endothelial cell of viscerocranial mucosa @@ -46298,7 +46263,6 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-14T10:57:26Z - CL:1000403 FMA:63134 endothelial cell of sinusoid @@ -46825,7 +46789,6 @@ radial glial cells acting as neural progenitors throughout life. An epithelial cell of the mucosa associated with facial skeleton. 2010-09-14T11:04:02Z - CL:1000440 FMA:70581 ecto-epithelial cell of viscerocranial mucosa @@ -47063,7 +47026,6 @@ radial glial cells acting as neural progenitors throughout life. An epithelial cell of the thymus. Epithelial reticular cells are pleomorphic, stellate, non-phagocytic cells which seem to be supportive in function and are held together by desmosomes. They replace the fibroblastoid reticular cells found in other lymphoid organs. Other epithelial cells in the medulla have the ultrastructure of secretory cells. Although different epithelial cells throughout the thymus appear alike by light microscopy their ultrastructure and function varies. 2010-09-13T02:34:22Z - CL:1000459 CALOHA:TS-1040 FMA:72208 epithelial cell of thymus gland @@ -47318,7 +47280,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -47333,14 +47295,14 @@ radial glial cells acting as neural progenitors throughout life. Type A cells are usually round and located in the upper part of the synovial intima. type A synovial cell - + - + PMID:10770586 @@ -47905,7 +47867,6 @@ radial glial cells acting as neural progenitors throughout life. A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone. 2010-09-15T03:01:54Z - CL:1000406 CALOHA:TS-2096 FMA:63875 MESH:D003239 @@ -48075,8 +48036,6 @@ radial glial cells acting as neural progenitors throughout life. The milk-producing cell of the alveolar unit that emerges during pregnancy. 2010-09-20T01:30:57Z - CL:0002230 - CL:1000476 FMA:74506 FMA:79866 epithelial cell of lactiferous gland @@ -48406,6 +48365,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -48426,10 +48389,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -48563,6 +48522,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -48575,10 +48538,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -48606,6 +48565,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -48622,14 +48589,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -48723,6 +48682,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -48731,10 +48694,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -48905,7 +48864,6 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-21T04:33:05Z - CL:1000475 FMA:75621 endocardial endothelial cell endothelial cell of endocardium @@ -48994,6 +48952,14 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + @@ -49018,14 +48984,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - @@ -49066,28 +49024,28 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + - - + + - - + + @@ -49747,7 +49705,6 @@ radial glial cells acting as neural progenitors throughout life. A transversely striated, synctial muscle cell, formed by the fusion of myoblasts. 2010-09-24T01:13:01Z - CL:0000369 FBbt:00005812 myotubule single cell sarcomere @@ -50200,23 +50157,23 @@ radial glial cells acting as neural progenitors throughout life. - + - + - + - + - + @@ -50308,28 +50265,28 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + - - + + - - + + @@ -50417,12 +50374,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -50553,6 +50510,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -50569,10 +50530,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -50637,6 +50594,18 @@ radial glial cells acting as neural progenitors throughout life. + + + + + + + + + + + + @@ -50653,18 +50622,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - - - - @@ -50744,17 +50701,17 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + + + + + @@ -51124,7 +51081,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -51322,6 +51279,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -51334,10 +51295,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -52094,17 +52051,17 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + + + + + @@ -52202,12 +52159,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -52236,12 +52193,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -52271,12 +52228,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -52305,12 +52262,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -52515,11 +52472,11 @@ radial glial cells acting as neural progenitors throughout life. - + - + @@ -52557,12 +52514,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -52725,12 +52682,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -52765,7 +52722,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -52851,7 +52808,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -52924,7 +52881,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -52990,6 +52947,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -53002,10 +52963,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -53040,12 +52997,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -53122,7 +53079,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -53196,7 +53153,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -53306,6 +53263,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -53314,10 +53275,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -53389,24 +53346,24 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + - - + + @@ -53492,12 +53449,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -53533,12 +53490,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -53891,11 +53848,11 @@ radial glial cells acting as neural progenitors throughout life. - + - + @@ -54343,6 +54300,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -54359,10 +54320,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -54450,20 +54407,20 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + - - + + - - + + @@ -54498,25 +54455,25 @@ radial glial cells acting as neural progenitors throughout life. - - - - - + - + - + - + + + + + @@ -54590,12 +54547,12 @@ radial glial cells acting as neural progenitors throughout life. - - + + - - + + @@ -55045,6 +55002,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -55053,10 +55014,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -55795,7 +55752,6 @@ radial glial cells acting as neural progenitors throughout life. 2011-02-28T03:48:11Z - CL:1000393 FMA:62104 KUPO:0001099 endothelial cell of vein @@ -59960,45 +59916,45 @@ radial glial cells acting as neural progenitors throughout life. - - - - - - - - - + - + - + - + - + - + - + - + + + + + + + + + @@ -61478,6 +61434,11 @@ radial glial cells acting as neural progenitors throughout life. A cone cell that detects long wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 564-580 nm. https://orcid.org/0000-0002-5260-9315 + L cone + L-cone + long wavelength sensitive cone + long- (L) wavelength-sensitive cone + long-wavelength cone cell CL:0003048 L cone cell @@ -61488,6 +61449,36 @@ radial glial cells acting as neural progenitors throughout life. A cone cell that detects long wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 564-580 nm. WikipediaVersioned:Cone_cell&oldid=1111888680 + + + + L cone + PMID:32555229 + + + + + L-cone + PMID:29603924 + + + + + long wavelength sensitive cone + PMID:31117170 + + + + + long- (L) wavelength-sensitive cone + https://doi.org/10.7554/eLife.39166 + + + + + long-wavelength cone + https://doi.org/10.1038/323623a0 + @@ -61503,6 +61494,11 @@ radial glial cells acting as neural progenitors throughout life. A cone cell that detects medium wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 534-545 nm. https://orcid.org/0000-0002-5260-9315 + M cone + M-cone + middle wavelength sensitive cone + middle- (M) wavelength-sensitive cone + middle-wavelength-sensitive (M) cone cell CL:0003049 M cone cell @@ -61513,6 +61509,36 @@ radial glial cells acting as neural progenitors throughout life. A cone cell that detects medium wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 534-545 nm. WikipediaVersioned:Cone_cell&oldid=1111888680 + + + + M cone + PMID:32555229 + + + + + M-cone + PMID:29603924 + + + + + middle wavelength sensitive cone + PMID:31117170 + + + + + middle- (M) wavelength-sensitive cone + https://doi.org/10.7554/eLife.39166 + + + + + middle-wavelength-sensitive (M) cone + https://opg.optica.org/josaa/abstract.cfm?URI=josaa-6-1-153 + @@ -61522,6 +61548,14 @@ radial glial cells acting as neural progenitors throughout life. A cone cell that detects short wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 420-440 nm. https://orcid.org/0000-0002-5260-9315 + S cone + S-(short-wavelength sensitive) cone + S-cone + S-cone photoreceptor + short wavelength sensitive cone + short- (S) wavelength-sensitive cone + short-wavelength sensitive cone + short-wavelength-sensitive (S) cone cell CL:0003050 S cone cell @@ -61532,6 +61566,54 @@ radial glial cells acting as neural progenitors throughout life. A cone cell that detects short wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 420-440 nm. WikipediaVersioned:Cone_cell&oldid=1111888680 + + + + S cone + PMID:32555229 + + + + + S-(short-wavelength sensitive) cone + PMID:31117170 + + + + + S-cone + PMID:32555229 + + + + + S-cone photoreceptor + https://doi.org/10.7554/eLife.39166 + + + + + short wavelength sensitive cone + PMID:31117170 + + + + + short- (S) wavelength-sensitive cone + https://doi.org/10.7554/eLife.39166 + + + + + short-wavelength sensitive cone + PMID:31117170 + + + + + short-wavelength-sensitive (S) cone + https://opg.optica.org/josaa/abstract.cfm?URI=josaa-6-1-153 + @@ -62044,7 +62126,7 @@ radial glial cells acting as neural progenitors throughout life. - + @@ -64717,15 +64799,25 @@ Covers cells actively being cultured or stored in a quiescent state for future u - - A muscle cell that is part of some visceral muscle + + + + + + + + + + + + A muscle cell that is part of some visceral muscle. FBbt:00005070 visceral muscle cell - A muscle cell that is part of some visceral muscle + A muscle cell that is part of some visceral muscle. GOC:dos @@ -64927,18 +65019,18 @@ Covers cells actively being cultured or stored in a quiescent state for future u - + A skeletal muscle satellite cell that has become mitotically active - typically following muscle damage. activated skeletal muscle satellite cell - + - + More accurately - transformation_of ? @@ -69427,7 +69519,6 @@ Covers cells actively being cultured or stored in a quiescent state for future u A CNS neuron of the cerebral cortex. - CL:0002609 BTO:0004102 FMA:84104 cortical neuron @@ -70691,27 +70782,22 @@ plexiform layer using GABA. - - - - - - - - - - - - - Neuroendocrine cells that are born in the nasal placode during embryonic development and migrate through the nose and forebrain to the hypothalamus, where they regulate reproduction. + + + + + + + + A neuroendocrine cell that secretes gonadotropin-releasing hormone (GnRH). A GnRH neuron is born in the nasal placode during embryonic development and migrates through the nose and forebrain to the hypothalamus. This cell regulates reproduction by secreting GnRH into the pituitary portal vessels to induce the release of gonadotropins into the general circulation. GnRH neuron GnRH-secreting neuron - gonadotropin releasing neuron + gonadotropin-releasing hormone neuron - Neuroendocrine cells that are born in the nasal placode during embryonic development and migrate through the nose and forebrain to the hypothalamus, where they regulate reproduction. + A neuroendocrine cell that secretes gonadotropin-releasing hormone (GnRH). A GnRH neuron is born in the nasal placode during embryonic development and migrates through the nose and forebrain to the hypothalamus. This cell regulates reproduction by secreting GnRH into the pituitary portal vessels to induce the release of gonadotropins into the general circulation. GOC:NV PMID:21828096 @@ -74709,7 +74795,6 @@ plexiform layer using GABA. An enterocyte that is part of the epithelium proper of large intestine. - CL:1000336 FMA:263090 FMA:263112 vacuolar absorptive cell of epithelium proper of large intestine @@ -74811,7 +74896,6 @@ plexiform layer using GABA. A basal cell found in the bronchus epithelium. - CL:0002331 FMA:263120 basal cell of bronchus basal cell of epithelium of bronchus @@ -76433,7 +76517,6 @@ plexiform layer using GABA. A blood vessel endothelial cell that is part of an arterial endothelium. - CL:0002542 BTO:0004758 FMA:67761 KUPO:0001095 @@ -77567,7 +77650,6 @@ plexiform layer using GABA. An epithelial cell that is part of the glomerular parietal epithelium. - CL:1000897 FMA:70968 KUPO:0001035 epithelial cell of parietal layer of glomerular capsule @@ -85587,7 +85669,6 @@ plexiform layer using GABA. A neuron that is part of a peripheral nervous system. 2014-06-25T02:28:17Z - CL:0000111 FMA:84664 PNS neuron peripheral neuron @@ -89617,43 +89698,43 @@ plexiform layer using GABA. - - - + + + A type of mouse mesothelial fibroblast that is derived from the neural crest, is localized on blood vessels, and is a key component of the pia and arachnoid membranes surrounding the brain. VLMC (Mus musculus) vascular leptomeningeal cell (Mmus) - + - + - + - + PMID:30096314 - + PMID:30096314 - + PMID:30096314 @@ -91714,7 +91795,6 @@ plexiform layer using GABA. A glial cell that myelinates axonal processes. - CL:0000328 myelinating glial cell @@ -92170,7 +92250,7 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances - A retinal ganglion cell ocated in the ganglion cell layer of the retina and projects to magnocellular cells in the lateral geniculate nucleus (LGN) as part of the magnocellular pathway in the visual system. They have large cell bodies as well as extensive branching dendrite networks and as such have large receptive fields. + A retinal ganglion cell located in the ganglion cell layer of the retina. This cell projects to magnocellular cells in the lateral geniculate nucleus (LGN). They have large cell bodies and extensive, branching dendritic networks that contribute to their large receptive fields. https://orcid.org/0000-0001-7258-9596 https://orcid.org/0000-0001-7655-4833 M cell @@ -92181,7 +92261,7 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances - A retinal ganglion cell ocated in the ganglion cell layer of the retina and projects to magnocellular cells in the lateral geniculate nucleus (LGN) as part of the magnocellular pathway in the visual system. They have large cell bodies as well as extensive branching dendrite networks and as such have large receptive fields. + A retinal ganglion cell located in the ganglion cell layer of the retina. This cell projects to magnocellular cells in the lateral geniculate nucleus (LGN). They have large cell bodies and extensive, branching dendritic networks that contribute to their large receptive fields. PMID:32533915 WikipediaVersioned:Parasol_cell&oldid=1032171532 @@ -93764,6 +93844,70 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + + + + + + + + + + + + + + + + + + A CD24-positive, CD-133-positive, vimentin-positive cell found scattered throughout a renal proximal tubule and that may participate in tubular regeneration. Compared to other proximal tubular cell types, this cell contains less cytoplasm, fewer mitochondria and no brush border. + 2023-03-07T14:17:39Z + CD133+CD24+CD106- tubular cell + CD24+CD133+ tubular cell + CD24-positive tubular cell + After acute tubular injury, this cell type becomes more numerous. In healthy rat kidneys, this cell is not detectable, whereas after unilateral ureteral obstruction (renal injury), it may appear de novo, arguing against the notion that this cell type represents a pre-existing progenitor cell population. In at least one study, data indicate that this cell type represents transiently dedifferentiated tubular cells involved in regeneration. + CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell + + + + + A CD24-positive, CD-133-positive, vimentin-positive cell found scattered throughout a renal proximal tubule and that may participate in tubular regeneration. Compared to other proximal tubular cell types, this cell contains less cytoplasm, fewer mitochondria and no brush border. + PMID:21281815 + PMID:23124355 + + + + + CD133+CD24+CD106- tubular cell + https://doi.org/10.1002/stem.1130 + + + + + CD24+CD133+ tubular cell + PMID:23124355 + + + + + CD24-positive tubular cell + PMID:23124355 + + + + + After acute tubular injury, this cell type becomes more numerous. In healthy rat kidneys, this cell is not detectable, whereas after unilateral ureteral obstruction (renal injury), it may appear de novo, arguing against the notion that this cell type represents a pre-existing progenitor cell population. In at least one study, data indicate that this cell type represents transiently dedifferentiated tubular cells involved in regeneration. + PMID:23124355 + + + + @@ -94388,6 +94532,392 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + + + + + + + + + + A star-shaped glial cell that is part of some retina. This cell links neurons to blood vessels and may provide structural and physiological support to optic nerve head axons. + + 2023-03-02T14:38:32Z + retinal astroglia + In response to elevated intraocular pressure, a retinal astrocyte may modulate extracellular matrix remodeling. In the human retina, a retinal astrocyte is GFAP-positive, SOD3-positive and GYPC-positive. + retinal astrocyte + + + + + A star-shaped glial cell that is part of some retina. This cell links neurons to blood vessels and may provide structural and physiological support to optic nerve head axons. + PMID:25236977 + PMID:33796062 + + + + + retinal astroglia + + PMID:33796062 + + + + + In response to elevated intraocular pressure, a retinal astrocyte may modulate extracellular matrix remodeling. In the human retina, a retinal astrocyte is GFAP-positive, SOD3-positive and GYPC-positive. + PMID:32555229 + PMID:33796062 + + + + + + + + + + + + + + + + + + + + + A myofibroblast that is part of an alveoli during alveolarization. The contractile force of this cell elongates the secondary crest, while producing a framework of elastin and tenascin. During the maturation of the septa, secondary crest myofibroblasts, together with matrix fibroblasts, secrete metalloproteinases and other ECM‐remodeling proteins to thin the septal tip ECM. The secondary crest myofibroblast continues producing elastin, eventually undergoing apoptosis during adulthood. + + + 2023-03-16T09:17:47Z + secondary-crest myofibroblast + SCMF + SCMFs + alveolar myofibroblast + secondary crest myofibroblast + + + + + A myofibroblast that is part of an alveoli during alveolarization. The contractile force of this cell elongates the secondary crest, while producing a framework of elastin and tenascin. During the maturation of the septa, secondary crest myofibroblasts, together with matrix fibroblasts, secrete metalloproteinases and other ECM‐remodeling proteins to thin the septal tip ECM. The secondary crest myofibroblast continues producing elastin, eventually undergoing apoptosis during adulthood. + PMID:31331942 + PMID:33624948 + + + + + secondary-crest myofibroblast + PMID:31331942 + + + + + SCMF + PMID:33624948 + + + + + + SCMFs + PMID:25448080 + + + + + + + alveolar myofibroblast + PMID:31331942 + + + + + + + + + + + + + + + + + + + A smooth muscle cell that is part of a bronchiole. + + + 2023-03-16T09:38:17Z + bronchiolar smooth muscle cell + + + + + A smooth muscle cell that is part of a bronchiole. + ISBN:9781260462982 + PMID:15347627 + + + + + + + + + A megakaryocyte that is resident in the lung connective tissue. + + + 2023-03-16T11:31:23Z + lung MKs + lung megakaryocyte + + + + + A megakaryocyte that is resident in the lung connective tissue. + PMID:33351116 + + + + + lung MKs + PMID:33351116 + + + + + + + + + + + + + + + + + + + + + A mucus secreting cell that is part of a submucosal gland of the trachea. + + + 2023-03-16T13:03:13Z + tracheal submucosal gland mucous cell + mucus secreting cell of trachea gland + + + + + A mucus secreting cell that is part of a submucosal gland of the trachea. + PMID:18931053 + PMID:29656943 + + + + + tracheal submucosal gland mucous cell + PMID:18931053 + + + + + + + + + + + + + + + + + + + A myoepithelial cell that is part of a submucosal gland of the trachea. + + + 2023-03-16T13:36:43Z + myoepithelial cell of trachea gland + + + + + A myoepithelial cell that is part of a submucosal gland of the trachea. + PMID:29656943 + + + + + + + + + + + + + + + + + + + A mucus secreting cell of a submucosal gland of the bronchus. + + + 2023-03-16T15:12:52Z + bronchial gland mucous cell + mucus secreting cell of bronchus submucosal gland + + + + + A mucus secreting cell of a submucosal gland of the bronchus. + PMID:19965983 + + + + + bronchial gland mucous cell + PMID:5487122 + + + + + + + + + + + + + + + An epithelial cell that is part of a collecting duct of an airway submucosal gland. + + + 2023-03-16T15:20:28Z + airway submucosal gland collecting duct epithelial cell + + + + + An epithelial cell that is part of a collecting duct of an airway submucosal gland. + PMID:25648514 + PMID:29656943 + + + + + + + + + + + + + + + A basal cell that is part of a duct of an airway submucosal gland. + + https://orcid.org/0000-0002-9185-3994 + 2023-03-16T15:51:39Z + airway submucosal gland duct basal cell + + + + + A basal cell that is part of a duct of an airway submucosal gland. + PMID:29656943 + PMID:35046051 + + + + + + + + + + + + + + + + + + + A fibroblast that is part of the fibrous layer of the perichondrium. This cell is responsible for collagen fiber production. + + + 2023-03-16T16:12:50Z + perichondrial fibroblast + + + + + A fibroblast that is part of the fibrous layer of the perichondrium. This cell is responsible for collagen fiber production. + wikipedia:Perichondrium + + + + + + + + + + + + + + + + + + + A perichondrial fibroblast that is part of the lung + + + 2023-03-16T16:15:39Z + PC-fibro + lung perichondrial fibroblast + + + + + A perichondrial fibroblast that is part of the lung + PMID:36543915 + + + + + PC-fibro + PMID:36543915 + + + + + @@ -95782,6 +96312,12 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + @@ -95938,12 +96474,6 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances - - - - - - @@ -98134,6 +98664,12 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + @@ -98200,6 +98736,12 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + @@ -98422,6 +98964,12 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + @@ -98518,6 +99066,12 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + @@ -99538,6 +100092,12 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + @@ -99880,6 +100440,12 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + @@ -99934,6 +100500,12 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + @@ -100132,12 +100704,6 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances - - - - - - @@ -100948,6 +101514,12 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + @@ -101314,6 +101886,18 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + + + + + + + @@ -101326,6 +101910,12 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + @@ -101932,6 +102522,12 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + @@ -101992,6 +102588,12 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -102010,17 +102642,27 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances - + - + - + + + + + + + + + + + diff --git a/cl.obo b/cl.obo index 5c91ec9fa..11f45b575 100644 --- a/cl.obo +++ b/cl.obo @@ -1,8 +1,5 @@ format-version: 1.2 -data-version: releases/2023-02-19 -subsetdef: 1_STAR "" -subsetdef: 2_STAR "" -subsetdef: 3_STAR "" +data-version: releases/2023-03-21 subsetdef: abnormal_slim "" subsetdef: added_for_HCA "" subsetdef: attribute_slim "" @@ -64,7 +61,6 @@ subsetdef: vertebrate_core "" synonymtypedef: ABBREVIATION "" synonymtypedef: abbreviation "abbreviation" synonymtypedef: blast_name "" -synonymtypedef: BRAND_NAME "" synonymtypedef: common_name "" synonymtypedef: COMPARATIVE_PREFERRED "" synonymtypedef: DEPRECATED "" @@ -80,14 +76,12 @@ synonymtypedef: in_part "" synonymtypedef: InChI "" synonymtypedef: InChIKey "" synonymtypedef: INCONSISTENT "" -synonymtypedef: INN "" synonymtypedef: IUPAC_NAME "" synonymtypedef: LATIN "" synonymtypedef: LATIN "latin term" synonymtypedef: MISSPELLING "" synonymtypedef: NON_MAMMAL "" synonymtypedef: PENDING_REVIEW "" -synonymtypedef: PLURAL "" synonymtypedef: PLURAL "plural term" synonymtypedef: PRO-short-label "" synonymtypedef: scientific_name "" @@ -112,7 +106,7 @@ property_value: dc-description "An ontology of cell types." xsd:string property_value: dc-title "Cell Ontology" xsd:string property_value: dcterms-license http://creativecommons.org/licenses/by/4.0/ property_value: has_ontology_root_term CL:0000000 -property_value: owl:versionInfo "2023-02-19" xsd:string +property_value: owl:versionInfo "2023-03-21" xsd:string [Term] id: BFO:0000002 @@ -179,8 +173,8 @@ relationship: part_of BFO:0000020 {all_only="true"} ! specifically dependent con id: BFO:0000023 name: role def: "A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts." [] -is_a: CHEBI:50906 ! role -equivalent_to: CHEBI:50906 ! role +is_a: CHEBI:50906 +equivalent_to: CHEBI:50906 [Term] id: BFO:0000031 @@ -363,12 +357,13 @@ union_of: CARO:0001000 ! multi-cell-part structure union_of: CARO:0010000 ! multicellular anatomical structure relationship: part_of CARO:0000012 ! multicellular organism property_value: http://purl.obolibrary.org/obo/IAO_creation_date "10.7.2011" xsd:string -property_value: IAO:0000117 "mah" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0001-9114-8737 [Term] id: CARO:0001010 -name: organism or virus or viroid +name: organism def: "Material anatomical entity that is a member of an individual species or is a viral or viroid particle." [] +synonym: "organism or virus or viroid" EXACT [] is_a: BFO:0000040 ! material entity property_value: http://purl.obolibrary.org/obo/IAO_creation_date "9/18/11" xsd:string property_value: IAO:0000117 "Melissa Haendel" xsd:string @@ -392,9 +387,9 @@ name: cellular organism def: "An individual member of a clade of cellular organisms." [] comment: A general term for organism that is agnostic about single cell vs multi-cellular. Note that this is a subclass of 'anatomical structure', meaning that an organism must be a connected structure. For example, if I take one plant and make a rooted cutting from a it, I now have two (clonally related) organisms. is_a: CARO:0000003 ! connected anatomical structure -is_a: CARO:0001010 ! organism or virus or viroid +is_a: CARO:0001010 ! organism property_value: http://purl.obolibrary.org/obo/IAO_creation_date "7.16.2011" xsd:string -property_value: IAO:0000117 "mah" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0001-9114-8737 [Term] id: CARO:0020000 @@ -413,7 +408,7 @@ id: CARO:0020003 name: cellular anatomical structure def: "An anatomical structure consisting of one or more cells." [] is_a: CARO:0000006 ! material anatomical entity -property_value: created_by "dos" xsd:string +created_by: https://orcid.org/0000-0002-7073-9172 creation_date: 2018-09-28T14:20:19Z [Term] @@ -423,11092 +418,183 @@ def: "Entity that is, is part of, or derived from an organism, virus, or viroid comment: Important for alignment with Darwin Core class "Organism". is_a: BFO:0000004 ! independent continuant -[Term] -id: CHEBI:10545 -name: electron -namespace: chebi_ontology -def: "Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV." [] -subset: 3_STAR -synonym: "beta" RELATED [IUPAC] -synonym: "beta(-)" RELATED [ChEBI] -synonym: "beta-particle" RELATED [IUPAC] -synonym: "e" RELATED [IUPAC] -synonym: "e(-)" RELATED [UniProt] -synonym: "e-" RELATED [KEGG_COMPOUND] -synonym: "electron" EXACT [KEGG_COMPOUND] -synonym: "electron" EXACT IUPAC_NAME [IUPAC] -synonym: "electron" EXACT [ChEBI] -synonym: "Elektron" RELATED [ChEBI] -synonym: "negatron" RELATED [IUPAC] -xref: KEGG:C05359 -xref: PMID:21614077 {source="Europe PMC"} -xref: Wikipedia:Electron -is_a: CHEBI:36338 ! lepton -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "0.000548579903" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "0.0" xsd:string - -[Term] -id: CHEBI:131565 -name: steroid aldehyde -namespace: chebi_ontology -def: "Any steroid substituted by a formyl group." [] -subset: 3_STAR -synonym: "steroid aldehydes" RELATED [ChEBI] -is_a: CHEBI:17478 ! aldehyde -is_a: CHEBI:35341 ! steroid - -[Term] -id: CHEBI:131604 -name: Mycoplasma genitalium metabolite -namespace: chebi_ontology -def: "Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium." [] -subset: 3_STAR -synonym: "Mycoplasma genitalium metabolites" RELATED [ChEBI] -is_a: CHEBI:76969 ! bacterial metabolite - -[Term] -id: CHEBI:131621 -name: C19-steroid -namespace: chebi_ontology -def: "A steroid compound with a structure based on a 19-carbon (androstane) skeleton." [] -subset: 3_STAR -synonym: "C19-steroids" RELATED [ChEBI] -is_a: CHEBI:35341 ! steroid -relationship: has_parent_hydride CHEBI:35509 ! androstane - -[Term] -id: CHEBI:131927 -name: dicarboxylic acids and O-substituted derivatives -namespace: chebi_ontology -def: "A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens." [] -subset: 3_STAR -synonym: "dicarboxylic acids and derivatives" RELATED [ChEBI] -is_a: CHEBI:36586 ! carbonyl compound - -[Term] -id: CHEBI:132153 -name: hyaluronate -namespace: chebi_ontology -def: "A carbohydrate acid derivative anion obtained by deprotonation of the carboxy groups of hyaluronic acid; major species at pH 7.3." [] -subset: 3_STAR -synonym: "hyaluronan" RELATED [UniProt] -synonym: "hyaluronate polyanion" RELATED [ChEBI] -is_a: CHEBI:61469 ! polyanionic polymer -is_a: CHEBI:63551 ! carbohydrate acid derivative anion -relationship: is_conjugate_base_of CHEBI:16336 ! hyaluronic acid -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "(C14H20NO11)n.H2O" xsd:string - -[Term] -id: CHEBI:136849 -name: 3-oxo-Delta(4)-steroid group -namespace: chebi_ontology -def: "An organic group derived from any 3-oxo-Delta(4)-steroid." [] -subset: 3_STAR -synonym: "a 3-oxo-Delta4-steroid group" RELATED [UniProt] -is_a: CHEBI:33247 ! organic group -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H6O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "94.111" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "94.04186" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1=C(C*)*C(CC1=O)*" xsd:string - -[Term] -id: CHEBI:136889 -name: 5beta steroid -namespace: chebi_ontology -def: "Any steroid that has beta-configuration at position 5." [] -subset: 3_STAR -synonym: "5beta steroids" RELATED [ChEBI] -synonym: "5beta-steroid" RELATED [ChEBI] -synonym: "5beta-steroids" RELATED [ChEBI] -is_a: CHEBI:35341 ! steroid - -[Term] -id: CHEBI:138103 -name: inorganic acid -namespace: chebi_ontology -def: "A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water." [] -subset: 3_STAR -synonym: "inorganic acids" RELATED [ChEBI] -synonym: "mineral acid" RELATED [ChEBI] -synonym: "mineral acids" RELATED [ChEBI] -xref: Wikipedia:Mineral_acid -is_a: CHEBI:39141 ! Bronsted acid - -[Term] -id: CHEBI:138366 -name: bile acids -namespace: chebi_ontology -def: "Any member of a group of hydroxy steroids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration, while in lower vertebrates, some bile acids, known as allo-bile acids, have 5alpha-configuration." [] -subset: 3_STAR -is_a: CHEBI:25384 ! monocarboxylic acid -is_a: CHEBI:35350 ! hydroxy steroid -is_a: CHEBI:36078 ! cholanoid - -[Term] -id: CHEBI:13850 -name: apoprotein -namespace: chebi_ontology -def: "An apoprotein is a protein devoid of its characteristic prosthetic group or metal." [] -subset: 3_STAR -synonym: "apoprotein" EXACT IUPAC_NAME [IUPAC] -synonym: "apoproteins" RELATED [ChEBI] -xref: KEGG:C16240 -is_a: CHEBI:38560 ! simple protein -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite - -[Term] -id: CHEBI:138675 -name: gas molecular entity -namespace: chebi_ontology -def: "Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa)." [] -subset: 3_STAR -synonym: "gas molecular entities" RELATED [ChEBI] -synonym: "gaseous molecular entities" RELATED [ChEBI] -synonym: "gaseous molecular entity" RELATED [ChEBI] -xref: Wikipedia:https\://en.wikipedia.org/wiki/Gas -is_a: CHEBI:33579 ! main group molecular entity - -[Term] -id: CHEBI:13941 -name: carbamate -namespace: chebi_ontology -subset: 3_STAR -synonym: "Carbamat" RELATED [ChEBI] -synonym: "carbamate" EXACT [UniProt] -synonym: "carbamate" EXACT IUPAC_NAME [IUPAC] -synonym: "carbamate ion" RELATED [ChemIDplus] -synonym: "carbamic acid, ion(1-)" RELATED [ChemIDplus] -synonym: "Karbamat" RELATED [ChEBI] -xref: Beilstein:3903503 {source="Beilstein"} -xref: CAS:302-11-4 {source="ChemIDplus"} -xref: Gmelin:239604 {source="Gmelin"} -is_a: CHEBI:37022 ! amino-acid anion -relationship: is_conjugate_base_of CHEBI:28616 ! carbamic acid -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2NO2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)/p-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KXDHJXZQYSOELW-UHFFFAOYSA-M" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "60.03212" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.00910" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC([O-])=O" xsd:string - -[Term] -id: CHEBI:139588 -name: alpha-hydroxy ketone -namespace: chebi_ontology -def: "An alpha-oxyketone that has a hydroxy group as the alpha-oxy moiety." [] -subset: 3_STAR -synonym: "alpha-hydroxy ketones" RELATED [ChEBI] -synonym: "alpha-hydroxy-ketone" RELATED [ChEBI] -synonym: "alpha-hydroxy-ketones" RELATED [ChEBI] -synonym: "alpha-hydroxyketone" RELATED [ChEBI] -synonym: "alpha-hydroxyketones" RELATED [ChEBI] -xref: PMID:15326516 {source="Europe PMC"} -xref: PMID:19908854 {source="Europe PMC"} -xref: PMID:20382022 {source="Europe PMC"} -xref: PMID:23295224 {source="Europe PMC"} -is_a: CHEBI:30879 ! alcohol -is_a: CHEBI:52396 ! alpha-oxyketone - -[Term] -id: CHEBI:139590 -name: primary alpha-hydroxy ketone -namespace: chebi_ontology -def: "An alpha-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a -CH2 (methylene) group." [] -subset: 3_STAR -synonym: "primary alpha-hydroxy ketones" RELATED [ChEBI] -synonym: "primary alpha-hydroxy-ketone" RELATED [ChEBI] -synonym: "primary alpha-hydroxy-ketones" RELATED [ChEBI] -synonym: "primary alpha-hydroxyketone" RELATED [ChEBI] -synonym: "primary alpha-hydroxyketones" RELATED [ChEBI] -is_a: CHEBI:139588 ! alpha-hydroxy ketone -is_a: CHEBI:15734 ! primary alcohol -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H3O2R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "59.044" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "59.01330" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "*C(C(O)([H])[H])=O" xsd:string - -[Term] -id: CHEBI:140601 -name: fatty acid 4:0 -namespace: chebi_ontology -def: "Any saturated fatty acid containing 4 carbons." [] -subset: 3_STAR -is_a: CHEBI:26666 ! short-chain fatty acid -relationship: is_conjugate_acid_of CHEBI:78115 ! fatty acid anion 4:0 -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO2R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "45.017" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.99765" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "*C(O)=O" xsd:string - -[Term] -id: CHEBI:142163 -name: 24G7 epitope -namespace: chebi_ontology -def: "An antigenic epitope recognized by an anti-bilirubin monoclonal antibody designated 24G7. A substructure of bilirubin IXalpha, it is the region containing the oxo group at C-1, the methyl group at C-2, C-(4, 5, 6, 9), and N-21 and -22." [] -subset: 3_STAR -is_a: CHEBI:24433 ! group -relationship: RO:0000087 CHEBI:53000 ! has role epitope -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C7H6N2O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "134.136" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "134.04801" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C(=CC(NC(=*)*)=*)(NC(C(C)=*)=O)*" xsd:string - -[Term] -id: CHEBI:14321 -name: glutamate(1-) -namespace: chebi_ontology -def: "An alpha-amino-acid anion that is the conjugate base of glutamic acid, having anionic carboxy groups and a cationic amino group" [] -subset: 3_STAR -synonym: "2-ammoniopentanedioate" RELATED [IUPAC] -synonym: "glutamate" RELATED [UniProt] -synonym: "glutamate(1-)" EXACT [JCBN] -synonym: "glutamic acid monoanion" RELATED [JCBN] -synonym: "hydrogen glutamate" EXACT IUPAC_NAME [IUPAC] -xref: Gmelin:327908 {source="Gmelin"} -is_a: CHEBI:33558 ! alpha-amino-acid anion -relationship: is_conjugate_acid_of CHEBI:29987 ! glutamate(2-) -relationship: is_conjugate_base_of CHEBI:18237 ! glutamic acid -relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H8NO4" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "WHUUTDBJXJRKMK-UHFFFAOYSA-M" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "146.12136" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "146.04588" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]C(CCC([O-])=O)C([O-])=O" xsd:string - -[Term] -id: CHEBI:15339 -name: acceptor -namespace: chebi_ontology -alt_id: CHEBI:13699 -alt_id: CHEBI:2377 -def: "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity." [] -subset: 3_STAR -synonym: "A" RELATED [KEGG_COMPOUND] -synonym: "accepteur" RELATED [ChEBI] -synonym: "Acceptor" EXACT [KEGG_COMPOUND] -synonym: "Akzeptor" RELATED [ChEBI] -synonym: "Hydrogen-acceptor" RELATED [KEGG_COMPOUND] -synonym: "Oxidized donor" RELATED [KEGG_COMPOUND] -xref: KEGG:C00028 -xref: KEGG:C16722 -is_a: CHEBI:51086 ! chemical role - [Term] id: CHEBI:15355 -name: acetylcholine namespace: chebi_ontology -alt_id: CHEBI:12686 -alt_id: CHEBI:13715 -alt_id: CHEBI:22197 -alt_id: CHEBI:2416 -alt_id: CHEBI:40559 def: "Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter." [ANON:ANON] -subset: 3_STAR -synonym: "2-acetyloxy-N,N,N-trimethylethanaminium" EXACT IUPAC_NAME [IUPAC] synonym: "2-acetyloxy-N,N,N-trimethylethanaminium" EXACT IUPAC_NAME [IUPAC:] synonym: "ACETYLCHOLINE" EXACT [PDBeChem:] -synonym: "ACETYLCHOLINE" EXACT [PDBeChem] -synonym: "Acetylcholine" EXACT [KEGG_COMPOUND] synonym: "Acetylcholine" EXACT [KEGG COMPOUND:] -synonym: "acetylcholine" EXACT [UniProt] -synonym: "ACh" RELATED [ChemIDplus] synonym: "ACh" RELATED [ChemIDplus:] -synonym: "Azetylcholin" RELATED [ChEBI] synonym: "Azetylcholin" RELATED [ChEBI:] synonym: "C7H16NO2" RELATED FORMULA [KEGG COMPOUND:] synonym: "CC(=O)OCC[N+](C)(C)C" RELATED SMILES [ChEBI:] -synonym: "choline acetate" RELATED [ChemIDplus] synonym: "choline acetate" RELATED [ChemIDplus:] synonym: "InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1" RELATED InChI [ChEBI:] synonym: "InChIKey=OIPILFWXSMYKGL-UHFFFAOYSA-N" RELATED InChIKey [ChEBI:] synonym: "O-Acetylcholine" RELATED [KEGG COMPOUND:] -synonym: "O-Acetylcholine" RELATED [KEGG_COMPOUND] -xref: Beilstein:1764436 {source="ChemIDplus"} -xref: CAS:51-84-3 {source="ChemIDplus"} -xref: CAS:51-84-3 {source="KEGG COMPOUND"} -xref: Drug_Central:65 {source="DrugCentral"} -xref: DrugBank:DB03128 -xref: Gmelin:326108 {source="Gmelin"} -xref: KEGG:C01996 -xref: LINCS:LSM-5888 -xref: PDBeChem:ACH -xref: PMID:14764638 {source="Europe PMC"} -xref: PMID:15014918 {source="Europe PMC"} -xref: PMID:15231705 {source="Europe PMC"} -xref: PMID:15361288 {source="Europe PMC"} -xref: PMID:18050502 {source="Europe PMC"} -xref: PMID:18407448 {source="Europe PMC"} -xref: PMID:19255787 {source="Europe PMC"} -xref: PMID:20963497 {source="Europe PMC"} -xref: PMID:21130809 {source="Europe PMC"} -xref: PMID:21246223 {source="Europe PMC"} -xref: PMID:21545631 {source="Europe PMC"} -xref: PMID:21601579 {source="Europe PMC"} -xref: Wikipedia:Acetylcholine -is_a: CHEBI:35287 ! acylcholine -is_a: CHEBI:47622 ! acetate ester -relationship: RO:0000087 CHEBI:24621 ! has role hormone -relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter -relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent -relationship: RO:0000087 CHEBI:38325 ! has role muscarinic agonist -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C7H16NO2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OIPILFWXSMYKGL-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "146.20748" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "146.11756" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC(=O)OCC[N+](C)(C)C" xsd:string - -[Term] -id: CHEBI:15366 -name: acetic acid -namespace: chebi_ontology -alt_id: CHEBI:22169 -alt_id: CHEBI:2387 -alt_id: CHEBI:40486 -def: "A simple monocarboxylic acid containing two carbons." [] -subset: 3_STAR -synonym: "ACETIC ACID" EXACT [PDBeChem] -synonym: "Acetic acid" EXACT [KEGG_COMPOUND] -synonym: "acetic acid" EXACT IUPAC_NAME [IUPAC] -synonym: "acide acetique" RELATED [ChemIDplus] -synonym: "AcOH" RELATED [ChEBI] -synonym: "CH3-COOH" RELATED [IUPAC] -synonym: "CH3CO2H" RELATED [ChEBI] -synonym: "E 260" RELATED [ChEBI] -synonym: "E-260" RELATED [ChEBI] -synonym: "E260" RELATED [ChEBI] -synonym: "Essigsaeure" RELATED [ChEBI] -synonym: "Ethanoic acid" RELATED [KEGG_COMPOUND] -synonym: "ethoic acid" RELATED [ChEBI] -synonym: "Ethylic acid" RELATED [ChemIDplus] -synonym: "HOAc" RELATED [ChEBI] -synonym: "INS No. 260" RELATED [ChEBI] -synonym: "MeCO2H" RELATED [ChEBI] -synonym: "MeCOOH" RELATED [ChEBI] -synonym: "Methanecarboxylic acid" RELATED [ChemIDplus] -xref: Beilstein:506007 {source="Beilstein"} -xref: CAS:64-19-7 {source="ChemIDplus"} -xref: CAS:64-19-7 {source="NIST Chemistry WebBook"} -xref: CAS:64-19-7 {source="KEGG COMPOUND"} -xref: Drug_Central:4211 {source="DrugCentral"} -xref: Gmelin:1380 {source="Gmelin"} -xref: HMDB:HMDB0000042 -xref: KEGG:C00033 -xref: KEGG:D00010 -xref: KNApSAcK:C00001176 -xref: LIPID_MAPS_instance:LMFA01010002 {source="LIPID MAPS"} -xref: MetaCyc:ACET -xref: PDBeChem:ACT -xref: PDBeChem:ACY -xref: PMID:12005138 {source="Europe PMC"} -xref: PMID:15107950 {source="Europe PMC"} -xref: PMID:16630552 {source="Europe PMC"} -xref: PMID:16774200 {source="Europe PMC"} -xref: PMID:17190852 {source="Europe PMC"} -xref: PMID:19416101 {source="Europe PMC"} -xref: PMID:19469536 {source="Europe PMC"} -xref: PMID:22153255 {source="Europe PMC"} -xref: PMID:22173419 {source="Europe PMC"} -xref: PPDB:1333 -xref: Reaxys:506007 {source="Reaxys"} -xref: Wikipedia:Acetic_acid -is_a: CHEBI:25384 ! monocarboxylic acid -relationship: is_conjugate_acid_of CHEBI:30089 ! acetate -relationship: RO:0000087 CHEBI:48356 ! has role protic solvent -relationship: RO:0000087 CHEBI:64049 ! has role food acidity regulator -relationship: RO:0000087 CHEBI:65256 ! has role antimicrobial food preservative -relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4O2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QTBSBXVTEAMEQO-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "60.05200" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.02113" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC(O)=O" xsd:string - -[Term] -id: CHEBI:15377 -name: water -namespace: chebi_ontology -alt_id: CHEBI:10743 -alt_id: CHEBI:13352 -alt_id: CHEBI:27313 -alt_id: CHEBI:42043 -alt_id: CHEBI:42857 -alt_id: CHEBI:43228 -alt_id: CHEBI:44292 -alt_id: CHEBI:44701 -alt_id: CHEBI:44819 -alt_id: CHEBI:5585 -def: "An oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms" [] -subset: 3_STAR -synonym: "[OH2]" RELATED [IUPAC] -synonym: "acqua" RELATED [ChEBI] -synonym: "agua" RELATED [ChEBI] -synonym: "aqua" RELATED [ChEBI] -synonym: "BOUND WATER" RELATED [PDBeChem] -synonym: "dihydridooxygen" RELATED [IUPAC] -synonym: "dihydrogen oxide" RELATED [IUPAC] -synonym: "eau" RELATED [ChEBI] -synonym: "H2O" RELATED [KEGG_COMPOUND] -synonym: "H2O" RELATED [UniProt] -synonym: "HOH" RELATED [ChEBI] -synonym: "hydrogen hydroxide" RELATED [ChEBI] -synonym: "oxidane" EXACT IUPAC_NAME [IUPAC] -synonym: "Wasser" RELATED [ChEBI] -synonym: "WATER" EXACT [PDBeChem] -synonym: "Water" EXACT [KEGG_COMPOUND] -synonym: "water" EXACT IUPAC_NAME [IUPAC] -xref: Beilstein:3587155 {source="Beilstein"} -xref: CAS:7732-18-5 {source="NIST Chemistry WebBook"} -xref: CAS:7732-18-5 {source="ChemIDplus"} -xref: CAS:7732-18-5 {source="KEGG COMPOUND"} -xref: Gmelin:117 {source="Gmelin"} -xref: HMDB:HMDB0002111 -xref: KEGG:C00001 -xref: KEGG:D00001 -xref: MetaCyc:WATER -xref: MolBase:1 -xref: PDBeChem:HOH -xref: Reaxys:3587155 {source="Reaxys"} -xref: Wikipedia:Water -is_a: CHEBI:33693 ! oxygen hydride -is_a: CHEBI:37176 ! mononuclear parent hydride -is_a: CHEBI:52625 ! inorganic hydroxy compound -relationship: is_conjugate_acid_of CHEBI:16234 ! hydroxide -relationship: is_conjugate_base_of CHEBI:29412 ! oxonium -relationship: RO:0000087 CHEBI:48360 ! has role amphiprotic solvent -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite -relationship: RO:0000087 CHEBI:76413 ! has role greenhouse gas -relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "H2O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O/h1H2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "XLYOFNOQVPJJNP-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "18.01530" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "18.01056" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]O[H]" xsd:string - -[Term] -id: CHEBI:15379 -name: dioxygen -namespace: chebi_ontology -alt_id: CHEBI:10745 -alt_id: CHEBI:13416 -alt_id: CHEBI:23833 -alt_id: CHEBI:25366 -alt_id: CHEBI:30491 -alt_id: CHEBI:44742 -alt_id: CHEBI:7860 -subset: 3_STAR -synonym: "[OO]" RELATED [MolBase] -synonym: "dioxygen" EXACT IUPAC_NAME [IUPAC] -synonym: "dioxygene" RELATED [ChEBI] -synonym: "Disauerstoff" RELATED [ChEBI] -synonym: "E 948" RELATED [ChEBI] -synonym: "E-948" RELATED [ChEBI] -synonym: "E948" RELATED [ChEBI] -synonym: "molecular oxygen" RELATED [ChEBI] -synonym: "O2" RELATED [UniProt] -synonym: "O2" RELATED [IUPAC] -synonym: "O2" RELATED [KEGG_COMPOUND] -synonym: "Oxygen" RELATED [KEGG_COMPOUND] -synonym: "OXYGEN MOLECULE" RELATED [PDBeChem] -xref: CAS:7782-44-7 {source="NIST Chemistry WebBook"} -xref: CAS:7782-44-7 {source="ChemIDplus"} -xref: CAS:7782-44-7 {source="KEGG COMPOUND"} -xref: Gmelin:485 {source="Gmelin"} -xref: HMDB:HMDB0001377 -xref: KEGG:C00007 -xref: KEGG:D00003 -xref: MetaCyc:OXYGEN-MOLECULE -xref: MolBase:750 -xref: PDBeChem:OXY -xref: PMID:10906528 {source="Europe PMC"} -xref: PMID:16977326 {source="Europe PMC"} -xref: PMID:18210929 {source="Europe PMC"} -xref: PMID:18638417 {source="Europe PMC"} -xref: PMID:19840863 {source="Europe PMC"} -xref: PMID:7710549 {source="Europe PMC"} -xref: PMID:9463773 {source="Europe PMC"} -xref: Wikipedia:Oxygen -is_a: CHEBI:138675 ! gas molecular entity -is_a: CHEBI:25362 ! elemental molecule -is_a: CHEBI:33263 ! diatomic oxygen -relationship: is_conjugate_base_of CHEBI:29793 ! hydridodioxygen(1+) -relationship: RO:0000087 CHEBI:27027 ! has role micronutrient -relationship: RO:0000087 CHEBI:33893 ! has role reagent -relationship: RO:0000087 CHEBI:35472 ! has role anti-inflammatory drug -relationship: RO:0000087 CHEBI:63248 ! has role oxidising agent -relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -relationship: RO:0000087 CHEBI:77974 ! has role food packaging gas -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "O2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/O2/c1-2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "MYMOFIZGZYHOMD-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "31.998" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "31.98983" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=O" xsd:string - -[Term] -id: CHEBI:15428 -name: glycine -namespace: chebi_ontology -alt_id: CHEBI:10792 -alt_id: CHEBI:14344 -alt_id: CHEBI:24368 -alt_id: CHEBI:42964 -alt_id: CHEBI:5460 -def: "The simplest (and the only achiral) proteinogenic amino acid, with a hydrogen atom as its side chain." [] -subset: 3_STAR -synonym: "Aminoacetic acid" RELATED [KEGG_COMPOUND] -synonym: "aminoacetic acid" EXACT IUPAC_NAME [IUPAC] -synonym: "Aminoessigsaeure" RELATED [ChEBI] -synonym: "aminoethanoic acid" RELATED [ChEBI] -synonym: "aminoethanoic acid" RELATED [JCBN] -synonym: "G" RELATED [ChEBI] -synonym: "Gly" RELATED [KEGG_COMPOUND] -synonym: "Glycin" RELATED [ChemIDplus] -synonym: "GLYCINE" EXACT [PDBeChem] -synonym: "Glycine" EXACT [KEGG_COMPOUND] -synonym: "glycine" EXACT IUPAC_NAME [IUPAC] -synonym: "Glycocoll" RELATED [ChemIDplus] -synonym: "Glykokoll" RELATED [ChEBI] -synonym: "Glyzin" RELATED [ChEBI] -synonym: "H2N-CH2-COOH" RELATED [IUPAC] -synonym: "Hgly" RELATED [IUPAC] -synonym: "Leimzucker" RELATED [ChemIDplus] -xref: Beilstein:635782 {source="Beilstein"} -xref: CAS:56-40-6 {source="NIST Chemistry WebBook"} -xref: CAS:56-40-6 {source="ChemIDplus"} -xref: CAS:56-40-6 {source="KEGG COMPOUND"} -xref: Drug_Central:1319 {source="DrugCentral"} -xref: DrugBank:DB00145 -xref: ECMDB:ECMDB00123 -xref: Gmelin:1808 {source="Gmelin"} -xref: HMDB:HMDB0000123 -xref: KEGG:C00037 -xref: KEGG:D00011 -xref: KNApSAcK:C00001361 -xref: MetaCyc:GLY -xref: PDBeChem:GLY -xref: PMID:10930630 {source="Europe PMC"} -xref: PMID:11019925 {source="Europe PMC"} -xref: PMID:11174716 {source="Europe PMC"} -xref: PMID:11542461 {source="Europe PMC"} -xref: PMID:11806864 {source="Europe PMC"} -xref: PMID:12631515 {source="Europe PMC"} -xref: PMID:12754315 {source="Europe PMC"} -xref: PMID:12770151 {source="Europe PMC"} -xref: PMID:12921899 {source="Europe PMC"} -xref: PMID:15331688 {source="Europe PMC"} -xref: PMID:15388434 {source="Europe PMC"} -xref: PMID:15710237 {source="Europe PMC"} -xref: PMID:16105183 {source="Europe PMC"} -xref: PMID:16151895 {source="Europe PMC"} -xref: PMID:16214212 {source="Europe PMC"} -xref: PMID:16417482 {source="Europe PMC"} -xref: PMID:16444815 {source="Europe PMC"} -xref: PMID:16664855 {source="Europe PMC"} -xref: PMID:16901953 {source="Europe PMC"} -xref: PMID:16918424 {source="Europe PMC"} -xref: PMID:16986325 {source="Europe PMC"} -xref: PMID:16998855 {source="Europe PMC"} -xref: PMID:17154252 {source="Europe PMC"} -xref: PMID:17383967 {source="Europe PMC"} -xref: PMID:17582620 {source="Europe PMC"} -xref: PMID:17970719 {source="Europe PMC"} -xref: PMID:18079355 {source="Europe PMC"} -xref: PMID:18396796 {source="Europe PMC"} -xref: PMID:18440992 {source="Europe PMC"} -xref: PMID:18593588 {source="Europe PMC"} -xref: PMID:18816054 {source="Europe PMC"} -xref: PMID:18840508 {source="Europe PMC"} -xref: PMID:19028609 {source="Europe PMC"} -xref: PMID:19120667 {source="Europe PMC"} -xref: PMID:19449910 {source="Europe PMC"} -xref: PMID:19526731 {source="Europe PMC"} -xref: PMID:19544666 {source="Europe PMC"} -xref: PMID:19738917 {source="Europe PMC"} -xref: PMID:19916621 {source="Europe PMC"} -xref: PMID:19924257 {source="Europe PMC"} -xref: PMID:21751272 {source="Europe PMC"} -xref: PMID:22044190 {source="Europe PMC"} -xref: PMID:22079563 {source="Europe PMC"} -xref: PMID:22234938 {source="Europe PMC"} -xref: PMID:22264337 {source="Europe PMC"} -xref: PMID:22293292 {source="Europe PMC"} -xref: PMID:22401276 {source="Europe PMC"} -xref: PMID:22434786 {source="Europe PMC"} -xref: Reaxys:635782 {source="Reaxys"} -xref: Wikipedia:Glycine -xref: YMDB:YMDB00016 -is_a: CHEBI:26650 ! serine family amino acid -relationship: is_conjugate_acid_of CHEBI:32508 ! glycinate -relationship: is_conjugate_base_of CHEBI:32507 ! glycinium -relationship: is_tautomer_of CHEBI:57305 ! glycine zwitterion -relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter -relationship: RO:0000087 CHEBI:27027 ! has role micronutrient -relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical -relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent -relationship: RO:0000087 CHEBI:64570 ! has role EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor -relationship: RO:0000087 CHEBI:64571 ! has role NMDA receptor agonist -relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H5NO2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "DHMQDGOQFOQNFH-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "75.06664" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "75.03203" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "NCC(O)=O" xsd:string - -[Term] -id: CHEBI:15440 -name: squalene -namespace: chebi_ontology -alt_id: CHEBI:10795 -alt_id: CHEBI:10843 -alt_id: CHEBI:15104 -alt_id: CHEBI:26746 -alt_id: CHEBI:9245 -def: "A triterpene consisting of 2,6,10,15,19,23-hexamethyltetracosane having six double bonds at the 2-, 6-, 10-, 14-, 18- and 22-positions with (all-E)-configuration." [] -subset: 3_STAR -synonym: "(6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene" EXACT IUPAC_NAME [IUPAC] -synonym: "(all-E)-2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene" RELATED [NIST_Chemistry_WebBook] -synonym: "Spinacene" RELATED [KEGG_COMPOUND] -synonym: "Squalene" EXACT [KEGG_COMPOUND] -synonym: "squalene" EXACT [UniProt] -synonym: "Supraene" RELATED [KEGG_COMPOUND] -xref: Beilstein:1728920 {source="Beilstein"} -xref: CAS:111-02-4 {source="KEGG COMPOUND"} -xref: CAS:111-02-4 {source="ChemIDplus"} -xref: CAS:111-02-4 {source="NIST Chemistry WebBook"} -xref: HMDB:HMDB0000256 -xref: KEGG:C00751 -xref: KNApSAcK:C00003755 -xref: LIPID_MAPS_instance:LMPR0106010002 {source="LIPID MAPS"} -xref: MetaCyc:SQUALENE -xref: PDBeChem:SQL -xref: PMID:16341241 {source="Europe PMC"} -xref: PMID:23625688 {source="Europe PMC"} -xref: PMID:24362891 {source="Europe PMC"} -xref: PMID:25286851 {source="Europe PMC"} -xref: PMID:25286853 {source="Europe PMC"} -xref: PMID:25987292 {source="Europe PMC"} -xref: Wikipedia:Squalene -is_a: CHEBI:35191 ! triterpene -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite -relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C30H50" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C30H50/c1-25(2)15-11-19-29(7)23-13-21-27(5)17-9-10-18-28(6)22-14-24-30(8)20-12-16-26(3)4/h15-18,23-24H,9-14,19-22H2,1-8H3/b27-17+,28-18+,29-23+,30-24+" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "YYGNTYWPHWGJRM-AAJYLUCBSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "410.730" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "410.39125" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC(C)=CCC\\C(C)=C\\CC\\C(C)=C\\CC\\C=C(/C)CC\\C=C(/C)CCC=C(C)C" xsd:string - -[Term] -id: CHEBI:15693 -name: aldose -namespace: chebi_ontology -alt_id: CHEBI:13755 -alt_id: CHEBI:22305 -alt_id: CHEBI:2561 -def: "Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals." [] -subset: 3_STAR -synonym: "Aldose" EXACT [KEGG_COMPOUND] -synonym: "aldoses" RELATED [ChEBI] -synonym: "an aldose" RELATED [UniProt] -xref: KEGG:C01370 -xref: Wikipedia:Aldose -is_a: CHEBI:35381 ! monosaccharide -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4O2(CH2O)n" xsd:string - -[Term] -id: CHEBI:15705 -name: L-alpha-amino acid -namespace: chebi_ontology -alt_id: CHEBI:13072 -alt_id: CHEBI:13243 -alt_id: CHEBI:13797 -alt_id: CHEBI:21224 -alt_id: CHEBI:6175 -def: "Any alpha-amino acid having L-configuration at the alpha-carbon." [] -subset: 3_STAR -synonym: "L-2-Amino acid" RELATED [KEGG_COMPOUND] -synonym: "L-alpha-amino acid" EXACT [IUPAC] -synonym: "L-alpha-amino acids" EXACT IUPAC_NAME [IUPAC] -synonym: "L-alpha-amino acids" RELATED [ChEBI] -synonym: "L-Amino acid" RELATED [KEGG_COMPOUND] -xref: KEGG:C00151 -is_a: CHEBI:33704 ! alpha-amino acid -relationship: is_conjugate_acid_of CHEBI:59814 ! L-alpha-amino acid anion -relationship: is_tautomer_of CHEBI:59869 ! L-alpha-amino acid zwitterion -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "74.05870" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "N[C@@H]([*])C(O)=O" xsd:string - -[Term] -id: CHEBI:15734 -name: primary alcohol -namespace: chebi_ontology -alt_id: CHEBI:13676 -alt_id: CHEBI:14887 -alt_id: CHEBI:26262 -alt_id: CHEBI:57489 -alt_id: CHEBI:8406 -def: "A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." [] -subset: 3_STAR -synonym: "1-Alcohol" RELATED [KEGG_COMPOUND] -synonym: "a primary alcohol" RELATED [UniProt] -synonym: "Primary alcohol" EXACT [KEGG_COMPOUND] -synonym: "primary alcohols" RELATED [ChEBI] -xref: KEGG:C00226 -is_a: CHEBI:30879 ! alcohol -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CH3OR" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "31.034" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "31.01839" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "*C(O)([H])[H]" xsd:string - -[Term] -id: CHEBI:15740 -name: formate -namespace: chebi_ontology -alt_id: CHEBI:14276 -alt_id: CHEBI:24081 -def: "A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects." [] -subset: 3_STAR -synonym: "aminate" RELATED [ChEBI] -synonym: "formate" EXACT IUPAC_NAME [IUPAC] -synonym: "formate" EXACT [UniProt] -synonym: "formiate" RELATED [ChEBI] -synonym: "formic acid, ion(1-)" RELATED [ChemIDplus] -synonym: "formylate" RELATED [ChEBI] -synonym: "HCO2 anion" RELATED [NIST_Chemistry_WebBook] -synonym: "hydrogen carboxylate" RELATED [ChEBI] -synonym: "methanoate" RELATED [ChEBI] -xref: Beilstein:1901205 {source="Beilstein"} -xref: CAS:71-47-6 {source="ChemIDplus"} -xref: CAS:71-47-6 {source="NIST Chemistry WebBook"} -xref: Gmelin:1006 {source="Gmelin"} -xref: HMDB:HMDB0000142 -xref: KEGG:C00058 -xref: MetaCyc:FORMATE -xref: PMID:17190852 {source="Europe PMC"} -xref: PMID:3946945 {source="Europe PMC"} -xref: Reaxys:1901205 {source="Reaxys"} -xref: UM-BBD_compID:c0106 {source="UM-BBD"} -xref: Wikipedia:Formate -is_a: CHEBI:35757 ! monocarboxylic acid anion -relationship: is_conjugate_base_of CHEBI:30751 ! formic acid -relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)/p-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BDAGIHXWWSANSR-UHFFFAOYSA-M" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "45.01744" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.99820" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]C([O-])=O" xsd:string - -[Term] -id: CHEBI:15841 -name: polypeptide -namespace: chebi_ontology -alt_id: CHEBI:14860 -alt_id: CHEBI:8314 -def: "A peptide containing ten or more amino acid residues." [] -subset: 3_STAR -synonym: "polipeptido" RELATED [ChEBI] -synonym: "Polypeptid" RELATED [ChEBI] -synonym: "Polypeptide" EXACT [KEGG_COMPOUND] -synonym: "polypeptides" EXACT IUPAC_NAME [IUPAC] -xref: KEGG:C00403 -is_a: CHEBI:16670 ! peptide -is_a: CHEBI:33839 ! macromolecule -property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H6N2O3R2(C2H2NOR)n" xsd:string - -[Term] -id: CHEBI:15986 -name: polynucleotide -namespace: chebi_ontology -alt_id: CHEBI:13672 -alt_id: CHEBI:14859 -alt_id: CHEBI:8312 -def: "A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues." [] -subset: 3_STAR -synonym: "Polynucleotide" EXACT [KEGG_COMPOUND] -synonym: "polynucleotides" RELATED [ChEBI] -xref: KEGG:C00419 -is_a: CHEBI:33695 ! information biomacromolecule -is_a: CHEBI:61120 ! nucleobase-containing molecular entity -relationship: has_part CHEBI:50319 ! nucleotide residue -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "(C5H8O6PR)n.C10H17O10PR2" xsd:string - -[Term] -id: CHEBI:16134 -name: ammonia -namespace: chebi_ontology -alt_id: CHEBI:13405 -alt_id: CHEBI:13406 -alt_id: CHEBI:13407 -alt_id: CHEBI:13771 -alt_id: CHEBI:22533 -alt_id: CHEBI:44269 -alt_id: CHEBI:44284 -alt_id: CHEBI:44404 -alt_id: CHEBI:7434 -def: "An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms." [] -subset: 3_STAR -synonym: "[NH3]" RELATED [MolBase] -synonym: "AMMONIA" EXACT [PDBeChem] -synonym: "Ammonia" EXACT [KEGG_COMPOUND] -synonym: "ammonia" EXACT IUPAC_NAME [IUPAC] -synonym: "ammoniac" RELATED [ChEBI] -synonym: "Ammoniak" RELATED [ChemIDplus] -synonym: "amoniaco" RELATED [ChEBI] -synonym: "azane" EXACT IUPAC_NAME [IUPAC] -synonym: "NH3" RELATED [KEGG_COMPOUND] -synonym: "NH3" RELATED [UniProt] -synonym: "NH3" RELATED [IUPAC] -synonym: "R-717" RELATED [ChEBI] -synonym: "spirit of hartshorn" RELATED [ChemIDplus] -xref: Beilstein:3587154 {source="Beilstein"} -xref: CAS:7664-41-7 {source="ChemIDplus"} -xref: CAS:7664-41-7 {source="NIST Chemistry WebBook"} -xref: CAS:7664-41-7 {source="KEGG COMPOUND"} -xref: Drug_Central:4625 {source="DrugCentral"} -xref: Gmelin:79 {source="Gmelin"} -xref: HMDB:HMDB0000051 -xref: KEGG:C00014 -xref: KEGG:D02916 -xref: KNApSAcK:C00007267 -xref: MetaCyc:AMMONIA -xref: MolBase:930 -xref: PDBeChem:NH3 -xref: PMID:110589 {source="Europe PMC"} -xref: PMID:11139349 {source="Europe PMC"} -xref: PMID:11540049 {source="Europe PMC"} -xref: PMID:11746427 {source="Europe PMC"} -xref: PMID:11783653 {source="Europe PMC"} -xref: PMID:13753780 {source="Europe PMC"} -xref: PMID:14663195 {source="Europe PMC"} -xref: PMID:15092448 {source="Europe PMC"} -xref: PMID:15094021 {source="Europe PMC"} -xref: PMID:15554424 {source="Europe PMC"} -xref: PMID:15969015 {source="Europe PMC"} -xref: PMID:16008360 {source="Europe PMC"} -xref: PMID:16050680 {source="Europe PMC"} -xref: PMID:16348008 {source="Europe PMC"} -xref: PMID:16349403 {source="Europe PMC"} -xref: PMID:16614889 {source="Europe PMC"} -xref: PMID:16664306 {source="Europe PMC"} -xref: PMID:16842901 {source="Europe PMC"} -xref: PMID:17025297 {source="Europe PMC"} -xref: PMID:17439666 {source="Europe PMC"} -xref: PMID:17569513 {source="Europe PMC"} -xref: PMID:17737668 {source="Europe PMC"} -xref: PMID:18670398 {source="Europe PMC"} -xref: PMID:22002069 {source="Europe PMC"} -xref: PMID:22081570 {source="Europe PMC"} -xref: PMID:22088435 {source="Europe PMC"} -xref: PMID:22100291 {source="Europe PMC"} -xref: PMID:22130175 {source="Europe PMC"} -xref: PMID:22150211 {source="Europe PMC"} -xref: PMID:22240068 {source="Europe PMC"} -xref: PMID:22290316 {source="Europe PMC"} -xref: PMID:22342082 {source="Europe PMC"} -xref: PMID:22385337 {source="Europe PMC"} -xref: PMID:22443779 {source="Europe PMC"} -xref: PMID:22560242 {source="Europe PMC"} -xref: Reaxys:3587154 {source="Reaxys"} -xref: Wikipedia:Ammonia -is_a: CHEBI:138675 ! gas molecular entity -is_a: CHEBI:35107 ! azane -is_a: CHEBI:37176 ! mononuclear parent hydride -relationship: is_conjugate_acid_of CHEBI:29337 ! azanide -relationship: is_conjugate_base_of CHEBI:28938 ! ammonium -relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin -relationship: RO:0000087 CHEBI:59740 ! has role nucleophilic reagent -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:77941 ! has role EC 3.5.1.4 (amidase) inhibitor -relationship: RO:0000087 CHEBI:78433 ! has role refrigerant -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "H3N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3N/h1H3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QGZKDVFQNNGYKY-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "17.03056" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "17.02655" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]N([H])[H]" xsd:string - -[Term] -id: CHEBI:16137 -name: chondroitin D-glucuronate -namespace: chebi_ontology -alt_id: CHEBI:13989 -alt_id: CHEBI:13992 -alt_id: CHEBI:23221 -alt_id: CHEBI:3673 -def: "A mucopolysaccharide composed of repeating beta-D-glucopyranuronosyl-(1->3)-beta-D-N-acetylgalactosaminyl units." [] -subset: 3_STAR -synonym: "Chondroitin" RELATED [KEGG_COMPOUND] -synonym: "Chondroitin-D-glucuronate" RELATED [KEGG_COMPOUND] -xref: KEGG:C00401 -xref: KEGG:G11334 -is_a: CHEBI:37395 ! mucopolysaccharide -relationship: is_conjugate_acid_of CHEBI:57652 ! chondroitin D-glucuronate anion -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -property_value: http://purl.obolibrary.org/obo/chebi/formula "(C14H21NO11)nH2O" xsd:string - -[Term] -id: CHEBI:16189 -name: sulfate -namespace: chebi_ontology -alt_id: CHEBI:15135 -alt_id: CHEBI:45687 -alt_id: CHEBI:9335 -def: "A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid." [] -subset: 3_STAR -synonym: "[SO4](2-)" RELATED [IUPAC] -synonym: "SO4(2-)" RELATED [IUPAC] -synonym: "Sulfate" EXACT [KEGG_COMPOUND] -synonym: "sulfate" EXACT [UniProt] -synonym: "sulfate" EXACT IUPAC_NAME [IUPAC] -synonym: "Sulfate anion(2-)" RELATED [HMDB] -synonym: "Sulfate dianion" RELATED [HMDB] -synonym: "SULFATE ION" RELATED [PDBeChem] -synonym: "Sulfate(2-)" RELATED [HMDB] -synonym: "Sulfuric acid ion(2-)" RELATED [HMDB] -synonym: "sulphate" RELATED [ChEBI] -synonym: "sulphate ion" RELATED [ChEBI] -synonym: "tetraoxidosulfate(2-)" EXACT IUPAC_NAME [IUPAC] -synonym: "tetraoxosulfate(2-)" EXACT IUPAC_NAME [IUPAC] -synonym: "tetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC] -xref: Beilstein:3648446 {source="Beilstein"} -xref: CAS:14808-79-8 {source="ChemIDplus"} -xref: CAS:14808-79-8 {source="NIST Chemistry WebBook"} -xref: Gmelin:2120 {source="Gmelin"} -xref: HMDB:HMDB0001448 -xref: KEGG:C00059 -xref: KEGG:D05963 -xref: MetaCyc:SULFATE -xref: PDBeChem:SO4 -xref: PMID:11200094 {source="Europe PMC"} -xref: PMID:11452993 {source="Europe PMC"} -xref: PMID:11581495 {source="Europe PMC"} -xref: PMID:11798107 {source="Europe PMC"} -xref: PMID:12166931 {source="Europe PMC"} -xref: PMID:12668033 {source="Europe PMC"} -xref: PMID:14597181 {source="Europe PMC"} -xref: PMID:15093386 {source="Europe PMC"} -xref: PMID:15984785 {source="Europe PMC"} -xref: PMID:16186560 {source="Europe PMC"} -xref: PMID:16345535 {source="Europe PMC"} -xref: PMID:16347366 {source="Europe PMC"} -xref: PMID:16348007 {source="Europe PMC"} -xref: PMID:16483812 {source="Europe PMC"} -xref: PMID:16534979 {source="Europe PMC"} -xref: PMID:16656509 {source="Europe PMC"} -xref: PMID:16742508 {source="Europe PMC"} -xref: PMID:16742518 {source="Europe PMC"} -xref: PMID:17120760 {source="Europe PMC"} -xref: PMID:17420092 {source="Europe PMC"} -xref: PMID:17439666 {source="Europe PMC"} -xref: PMID:17709180 {source="Europe PMC"} -xref: PMID:18398178 {source="Europe PMC"} -xref: PMID:18815700 {source="Europe PMC"} -xref: PMID:18846414 {source="Europe PMC"} -xref: PMID:19047345 {source="Europe PMC"} -xref: PMID:19244483 {source="Europe PMC"} -xref: PMID:19544990 {source="Europe PMC"} -xref: PMID:19628332 {source="Europe PMC"} -xref: PMID:19812358 {source="Europe PMC"} -xref: PMID:30398859 {source="Europe PMC"} -xref: Reaxys:3648446 {source="Reaxys"} -xref: Wikipedia:Sulfate -is_a: CHEBI:33482 ! sulfur oxoanion -is_a: CHEBI:48154 ! sulfur oxide -is_a: CHEBI:79388 ! divalent inorganic anion -relationship: is_conjugate_base_of CHEBI:45696 ! hydrogensulfate -relationship: RO:0000087 CHEBI:23357 ! has role cofactor -relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "O4S" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QAOWNCQODCNURD-UHFFFAOYSA-L" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "96.06360" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.95283" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]S([O-])(=O)=O" xsd:string - -[Term] -id: CHEBI:16234 -name: hydroxide -namespace: chebi_ontology -alt_id: CHEBI:13365 -alt_id: CHEBI:13419 -alt_id: CHEBI:44641 -alt_id: CHEBI:5594 -subset: 3_STAR -synonym: "HO-" RELATED [KEGG_COMPOUND] -synonym: "hydridooxygenate(1-)" EXACT IUPAC_NAME [IUPAC] -synonym: "hydroxide" EXACT IUPAC_NAME [IUPAC] -synonym: "HYDROXIDE ION" RELATED [PDBeChem] -synonym: "Hydroxide ion" RELATED [KEGG_COMPOUND] -synonym: "OH(-)" RELATED [IUPAC] -synonym: "OH-" RELATED [KEGG_COMPOUND] -synonym: "oxidanide" EXACT IUPAC_NAME [IUPAC] -xref: CAS:14280-30-9 {source="ChemIDplus"} -xref: CAS:14280-30-9 {source="NIST Chemistry WebBook"} -xref: Gmelin:24714 {source="Gmelin"} -xref: KEGG:C01328 -xref: PDBeChem:OH -is_a: CHEBI:33693 ! oxygen hydride -relationship: is_conjugate_base_of CHEBI:15377 ! water -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "HO" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O/h1H2/p-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "XLYOFNOQVPJJNP-UHFFFAOYSA-M" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "17.00734" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "17.00329" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-][H]" xsd:string - -[Term] -id: CHEBI:16336 -name: hyaluronic acid -namespace: chebi_ontology -alt_id: CHEBI:14412 -alt_id: CHEBI:24622 -alt_id: CHEBI:24623 -alt_id: CHEBI:5772 -def: "A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells." [] -subset: 3_STAR -synonym: "[beta-D-glucopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)]n" RELATED [ChEBI] -synonym: "[beta-N-Acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)]n" RELATED [KEGG_COMPOUND] -synonym: "acide hyaluronique" RELATED [ChEBI] -synonym: "acido hialuronico" RELATED [ChEBI] -synonym: "hyaluronan" RELATED [ChEBI] -synonym: "Hyaluronic acid" EXACT [KEGG_COMPOUND] -synonym: "Hyaluronsaeure" RELATED [ChEBI] -xref: Beilstein:8538277 {source="Beilstein"} -xref: CAS:9004-61-9 {source="KEGG COMPOUND"} -xref: CAS:9004-61-9 {source="ChemIDplus"} -xref: HMDB:HMDB0010366 -xref: KEGG:C00518 -xref: KEGG:D08043 -xref: KEGG:G10505 -xref: PMID:11122186 {source="Europe PMC"} -xref: PMID:18056362 {source="Europe PMC"} -xref: PMID:18290544 {source="Europe PMC"} -xref: Reaxys:8187837 {source="Reaxys"} -xref: Wikipedia:Hyaluronan -is_a: CHEBI:37395 ! mucopolysaccharide -is_a: CHEBI:72813 ! exopolysaccharide -relationship: is_conjugate_acid_of CHEBI:132153 ! hyaluronate -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "(C14H21NO12)n" xsd:string - -[Term] -id: CHEBI:16480 -name: nitric oxide -namespace: chebi_ontology -alt_id: CHEBI:14657 -alt_id: CHEBI:25546 -alt_id: CHEBI:44452 -alt_id: CHEBI:7583 -def: "A nitrogen oxide which is a free radical, each molecule of which consists of one nitrogen and one oxygen atom." [] -subset: 3_STAR -synonym: "(.)NO" RELATED [ChEBI] -synonym: "(NO)(.)" RELATED [IUPAC] -synonym: "[NO]" RELATED [MolBase] -synonym: "EDRF" RELATED [ChEBI] -synonym: "endothelium-derived relaxing factor" RELATED [ChEBI] -synonym: "mononitrogen monoxide" RELATED [ChemIDplus] -synonym: "monoxido de nitrogeno" RELATED [ChEBI] -synonym: "monoxyde d'azote" RELATED [ChEBI] -synonym: "Nitric oxide" EXACT [KEGG_COMPOUND] -synonym: "nitric oxide" EXACT [UniProt] -synonym: "nitrogen monooxide" RELATED [IUPAC] -synonym: "Nitrogen monoxide" RELATED [KEGG_COMPOUND] -synonym: "nitrogen monoxide" RELATED [IUPAC] -synonym: "nitrosyl" RELATED [IUPAC] -synonym: "NO" RELATED [KEGG_COMPOUND] -synonym: "NO(.)" RELATED [IUPAC] -synonym: "oxido de nitrogeno(II)" RELATED [ChEBI] -synonym: "oxido nitrico" RELATED [ChEBI] -synonym: "oxidonitrogen(.)" EXACT IUPAC_NAME [IUPAC] -synonym: "oxoazanyl" EXACT IUPAC_NAME [IUPAC] -synonym: "oxyde azotique" RELATED [ChEBI] -synonym: "oxyde nitrique" RELATED [ChEBI] -synonym: "Stickstoff(II)-oxid" RELATED [ChEBI] -synonym: "Stickstoffmonoxid" RELATED [ChEBI] -xref: CAS:10102-43-9 {source="KEGG COMPOUND"} -xref: CAS:10102-43-9 {source="NIST Chemistry WebBook"} -xref: CAS:10102-43-9 {source="ChemIDplus"} -xref: DrugBank:DB00435 -xref: Gmelin:451 {source="Gmelin"} -xref: KEGG:C00533 -xref: KEGG:D00074 -xref: MolBase:943 -xref: PDBeChem:NO -xref: Reaxys:3587257 {source="Reaxys"} -xref: Wikipedia:Nitric_oxide -is_a: CHEBI:35196 ! nitrogen oxide -is_a: CHEBI:36871 ! inorganic radical -is_a: CHEBI:62764 ! reactive nitrogen species -relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter -relationship: RO:0000087 CHEBI:35523 ! has role bronchodilator agent -relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent -relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger -relationship: RO:0000087 CHEBI:62488 ! has role signalling molecule -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "NO" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/NO/c1-2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "MWUXSHHQAYIFBG-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "30.00614" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "29.99799" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[N]=O" xsd:string - -[Term] -id: CHEBI:16541 -name: protein polypeptide chain -namespace: chebi_ontology -alt_id: CHEBI:8526 -def: "A naturally occurring polypeptide synthesized at the ribosome." [] -subset: 3_STAR -synonym: "a protein" RELATED [UniProt] -synonym: "polypeptide chain" RELATED [ChEBI] -synonym: "Protein" RELATED [KEGG_COMPOUND] -synonym: "protein polypeptide chains" RELATED [ChEBI] -xref: KEGG:C00017 -is_a: CHEBI:15841 ! polypeptide -relationship: has_part CHEBI:33700 ! proteinogenic amino-acid residue - -[Term] -id: CHEBI:16646 -name: carbohydrate -namespace: chebi_ontology -alt_id: CHEBI:15131 -alt_id: CHEBI:23008 -alt_id: CHEBI:9318 -def: "Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates." [] -subset: 3_STAR -synonym: "a carbohydrate" RELATED [UniProt] -synonym: "carbohidrato" RELATED [IUPAC] -synonym: "carbohidratos" RELATED [IUPAC] -synonym: "carbohydrate" EXACT IUPAC_NAME [IUPAC] -synonym: "carbohydrates" EXACT IUPAC_NAME [IUPAC] -synonym: "glucide" RELATED [ChEBI] -synonym: "glucides" RELATED [ChEBI] -synonym: "glucido" RELATED [ChEBI] -synonym: "glucidos" RELATED [ChEBI] -synonym: "hydrates de carbone" RELATED [ChEBI] -synonym: "Kohlenhydrat" RELATED [ChEBI] -synonym: "Kohlenhydrate" RELATED [ChEBI] -synonym: "saccharide" RELATED [IUPAC] -synonym: "saccharides" RELATED [IUPAC] -synonym: "saccharidum" RELATED [ChEBI] -xref: Wikipedia:Carbohydrate -is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives [Term] id: CHEBI:16670 -name: peptide namespace: chebi_ontology -alt_id: CHEBI:14753 -alt_id: CHEBI:25906 -alt_id: CHEBI:7990 def: "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid." [ANON:ANON] -def: "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." [] -subset: 3_STAR synonym: "C2H4NO2R(C2H2NOR)n" RELATED FORMULA [KEGG COMPOUND:] synonym: "Peptid" RELATED [ChEBI:] -synonym: "Peptid" RELATED [ChEBI] -synonym: "Peptide" EXACT [KEGG_COMPOUND] synonym: "Peptide" EXACT [KEGG COMPOUND:] synonym: "peptides" EXACT IUPAC_NAME [IUPAC:] -synonym: "peptides" EXACT IUPAC_NAME [IUPAC] -synonym: "peptido" RELATED [ChEBI] synonym: "peptido" RELATED [ChEBI:] synonym: "peptidos" RELATED [ChEBI:] -synonym: "peptidos" RELATED [ChEBI] -xref: KEGG:C00012 -is_a: CHEBI:37622 ! carboxamide -is_a: CHEBI:50047 ! organic amino compound -relationship: has_part CHEBI:33708 ! amino-acid residue -relationship: is_tautomer_of CHEBI:60466 ! peptide zwitterion -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "(C2H2NOR)nC2H3NOR" xsd:string - -[Term] -id: CHEBI:166902 -name: noradrenaline(1+) -namespace: chebi_ontology -subset: 2_STAR -synonym: "noradrenaline" RELATED [UniProt] -is_a: CHEBI:25697 ! organic cation -is_a: CHEBI:35274 ! ammonium ion derivative -relationship: is_conjugate_acid_of CHEBI:33569 ! noradrenaline -property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H12NO3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-UHFFFAOYSA-O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "170.187" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "170.08117" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1=CC(=CC(=C1O)O)C(C[NH3+])O" xsd:string - -[Term] -id: CHEBI:167559 -name: glycan -namespace: chebi_ontology -def: "Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001." [] -subset: 3_STAR -synonym: "glycans" RELATED [ChEBI] -is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives - -[Term] -id: CHEBI:16765 -name: tryptamine -namespace: chebi_ontology -alt_id: CHEBI:15274 -alt_id: CHEBI:27161 -alt_id: CHEBI:46157 -alt_id: CHEBI:9767 -def: "An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position." [] -subset: 3_STAR -synonym: "1H-indole-3-ethanamine" RELATED [NIST_Chemistry_WebBook] -synonym: "2-(1H-INDOL-3-YL)ETHANAMINE" RELATED [PDBeChem] -synonym: "2-(1H-indol-3-yl)ethanamine" EXACT IUPAC_NAME [IUPAC] -synonym: "2-(3-indolyl)ethylamine" RELATED [ChemIDplus] -synonym: "3-(2-Aminoethyl)indole" RELATED [KEGG_COMPOUND] -synonym: "Tryptamine" EXACT [KEGG_COMPOUND] -xref: Beilstein:125513 {source="Beilstein"} -xref: CAS:61-54-1 {source="ChemIDplus"} -xref: CAS:61-54-1 {source="NIST Chemistry WebBook"} -xref: CAS:61-54-1 {source="KEGG COMPOUND"} -xref: DrugBank:DB08653 -xref: Gmelin:603448 {source="Gmelin"} -xref: HMDB:HMDB0000303 -xref: KEGG:C00398 -xref: KNApSAcK:C00001434 -xref: MetaCyc:TRYPTAMINE -xref: PDBeChem:TSS -xref: PMID:16126914 {source="Europe PMC"} -xref: PMID:22770225 {source="Europe PMC"} -xref: PMID:24345948 {source="Europe PMC"} -xref: PMID:24558969 {source="Europe PMC"} -xref: Reaxys:125513 {source="Reaxys"} -xref: Wikipedia:Tryptamine -is_a: CHEBI:27162 ! tryptamines -is_a: CHEBI:38631 ! aminoalkylindole -is_a: CHEBI:38958 ! indole alkaloid -is_a: CHEBI:64365 ! aralkylamino compound -relationship: is_conjugate_base_of CHEBI:57887 ! tryptaminium -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H12N2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "APJYDQYYACXCRM-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "160.21570" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "160.10005" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "NCCc1c[nH]c2ccccc12" xsd:string - -[Term] -id: CHEBI:16796 -name: melatonin -namespace: chebi_ontology -alt_id: CHEBI:14577 -alt_id: CHEBI:25180 -alt_id: CHEBI:6730 -def: "A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen atom is replaced by a 2-(5-methoxy-1H-indol-3-yl)ethyl group. It is a hormone secreted by the pineal gland in humans." [] -subset: 3_STAR -synonym: "5-methoxy-N-acetyltryptamine" RELATED [ChemIDplus] -synonym: "Melatonin" EXACT [KEGG_COMPOUND] -synonym: "melatonin" EXACT [UniProt] -synonym: "melatonine" RELATED [ChEBI] -synonym: "N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide" EXACT IUPAC_NAME [IUPAC] -synonym: "N-[2-(5-methoxyindol-3-yl)ethyl]acetamide" RELATED [NIST_Chemistry_WebBook] -synonym: "N-Acetyl-5-methoxytryptamine" RELATED [KEGG_COMPOUND] -xref: Beilstein:205542 {source="Beilstein"} -xref: CAS:73-31-4 {source="ChemIDplus"} -xref: CAS:73-31-4 {source="NIST Chemistry WebBook"} -xref: CAS:73-31-4 {source="KEGG COMPOUND"} -xref: Drug_Central:1672 {source="DrugCentral"} -xref: DrugBank:DB01065 -xref: HMDB:HMDB0001389 -xref: KEGG:C01598 -xref: KEGG:D08170 -xref: LINCS:LSM-4779 -xref: MetaCyc:N-ACETYL-5-METHOXY-TRYPTAMINE -xref: PDBeChem:ML1 -xref: PMID:16678784 {source="Europe PMC"} -xref: PMID:18212404 {source="Europe PMC"} -xref: PMID:18485664 {source="Europe PMC"} -xref: PMID:8290600 {source="Europe PMC"} -xref: Reaxys:205542 {source="Reaxys"} -xref: Wikipedia:Melatonin -is_a: CHEBI:22160 ! acetamides -is_a: CHEBI:27162 ! tryptamines -relationship: has_functional_parent CHEBI:16765 ! tryptamine -relationship: RO:0000087 CHEBI:176497 ! has role geroprotector -relationship: RO:0000087 CHEBI:24621 ! has role hormone -relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant -relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger -relationship: RO:0000087 CHEBI:50847 ! has role immunological adjuvant -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C13H16N2O2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "DRLFMBDRBRZALE-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "232.283" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "232.12118" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C=1C=C(C=C2C(=CNC12)CCNC(=O)C)OC" xsd:string - -[Term] -id: CHEBI:16865 -name: gamma-aminobutyric acid -namespace: chebi_ontology -alt_id: CHEBI:1786 -alt_id: CHEBI:193777 -alt_id: CHEBI:20318 -alt_id: CHEBI:40483 -def: "A gamma-amino acid that is butanoic acid with the amino substituent located at C-4." [] -def: "An amino fatty acid composed of butanoic acid with the amino substituent at C-4." [ANON:ANON] -subset: 3_STAR -synonym: "4-Aminobutanoic acid" RELATED [KEGG COMPOUND:] -synonym: "4-Aminobutanoic acid" RELATED [KEGG_COMPOUND] -synonym: "4-aminobutanoic acid" EXACT IUPAC_NAME [IUPAC] -synonym: "4-aminobutanoic acid" EXACT IUPAC_NAME [IUPAC:] -synonym: "4-aminobutanoic acid" RELATED [UniProt:] -synonym: "4-aminobutanoic acid" RELATED [ChEBI:] -synonym: "4-aminobutanoic acid" RELATED [ChEBI] -synonym: "4-Aminobutyric acid" RELATED [KEGG_COMPOUND] -synonym: "4-Aminobutyric acid" RELATED [KEGG COMPOUND:] -synonym: "4-aminobutyric acid" RELATED [ChEBI] -synonym: "4-aminobutyric acid" RELATED [ChEBI:] -synonym: "4Abu" RELATED [ChEBI] -synonym: "C4H9NO2" RELATED FORMULA [KEGG COMPOUND:] -synonym: "GABA" RELATED [IUPHAR:] -synonym: "GABA" RELATED [KEGG_COMPOUND] -synonym: "GABA" RELATED [IUPHAR] -synonym: "GAMMA-AMINO-BUTANOIC ACID" RELATED [PDBeChem] -synonym: "GAMMA-AMINO-BUTANOIC ACID" RELATED [PDBeChem:] -synonym: "gamma-amino-n-butyric acid" RELATED [NIST_Chemistry_WebBook] -synonym: "gamma-amino-n-butyric acid" RELATED [NIST Chemistry WebBook:] -synonym: "gamma-aminobutanoic acid" RELATED [NIST_Chemistry_WebBook] -synonym: "gamma-aminobutanoic acid" RELATED [NIST Chemistry WebBook:] -synonym: "gamma-Aminobuttersaeure" RELATED [NIST Chemistry WebBook:] -synonym: "gamma-Aminobuttersaeure" RELATED [NIST_Chemistry_WebBook] -synonym: "gamma-Aminobutyric acid" EXACT [KEGG COMPOUND:] -synonym: "gamma-Aminobutyric acid" EXACT [KEGG_COMPOUND] -synonym: "gamma-aminobutyric acid" EXACT [NIST_Chemistry_WebBook] -synonym: "gamma-aminobutyric acid" EXACT [NIST Chemistry WebBook:] -synonym: "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)" RELATED InChI [ChEBI:] -synonym: "InChIKey=BTCSSZJGUNDROE-UHFFFAOYSA-N" RELATED InChIKey [ChEBI:] -synonym: "NCCCC(O)=O" RELATED SMILES [ChEBI:] -synonym: "omega-aminobutyric acid" RELATED [NIST_Chemistry_WebBook] -synonym: "omega-aminobutyric acid" RELATED [NIST Chemistry WebBook:] -synonym: "piperidic acid" RELATED [ChemIDplus:] -synonym: "piperidic acid" RELATED [ChemIDplus] -synonym: "piperidinic acid" RELATED [ChemIDplus:] -synonym: "piperidinic acid" RELATED [ChemIDplus] -xref: Beilstein:906818 {source="Beilstein"} -xref: BPDB:2298 -xref: CAS:56-12-2 {source="ChemIDplus"} -xref: CAS:56-12-2 {source="NIST Chemistry WebBook"} -xref: CAS:56-12-2 {source="KEGG COMPOUND"} -xref: Drug_Central:1262 {source="DrugCentral"} -xref: DrugBank:DB02530 -xref: Gmelin:49775 {source="Gmelin"} -xref: HMDB:HMDB0000112 -xref: KEGG:C00334 -xref: KEGG:D00058 -xref: KNApSAcK:C00001337 -xref: LIPID_MAPS_instance:LMFA01100039 {source="LIPID MAPS"} -xref: MetaCyc:4-AMINO-BUTYRATE -xref: PDBeChem:ABU -xref: PMID:10630630 {source="Europe PMC"} -xref: PMID:10930630 {source="Europe PMC"} -xref: PMID:16276116 {source="Europe PMC"} -xref: PMID:21614609 {source="Europe PMC"} -xref: PMID:22770225 {source="Europe PMC"} -xref: Reaxys:906818 {source="Reaxys"} -xref: Wikipedia:Gamma-Aminobutyric_acid -is_a: CHEBI:25384 ! monocarboxylic acid -is_a: CHEBI:33707 ! gamma-amino acid -relationship: has_functional_parent CHEBI:30772 ! butyric acid -relationship: is_conjugate_acid_of CHEBI:30566 ! gamma-aminobutyrate -relationship: is_tautomer_of CHEBI:59888 ! gamma-aminobutyric acid zwitterion -relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter -relationship: RO:0000087 CHEBI:62488 ! has role signalling molecule -relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H9NO2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BTCSSZJGUNDROE-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "103.11980" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "103.06333" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "NCCCC(O)=O" xsd:string - -[Term] -id: CHEBI:16990 -name: bilirubin IXalpha -namespace: chebi_ontology -alt_id: CHEBI:13898 -alt_id: CHEBI:22870 -alt_id: CHEBI:3099 -def: "A member of the class of biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin." [] -subset: 3_STAR -synonym: "1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinylbiline-8,12-dipropionic acid" RELATED [ChemIDplus] -synonym: "2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid" RELATED [ChemIDplus] -synonym: "2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid" RELATED [IUPAC] -synonym: "3,18-diethenyl-2,7,13,17-tetramethyl-1,19-dioxo-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid" EXACT IUPAC_NAME [IUPAC] -synonym: "8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-3,18-divinylbiladiene-ac-1,19(21H,24H)-dione" RELATED [JCBN] -synonym: "Bilirubin" RELATED [KEGG_COMPOUND] -synonym: "bilirubin" EXACT IUPAC_NAME [IUPAC] -synonym: "bilirubin(Z,Z)" RELATED [ChEBI] -synonym: "bilirubin-IXalpha" RELATED [ChEBI] -xref: Beilstein:74376 {source="Beilstein"} -xref: CAS:635-65-4 {source="KEGG COMPOUND"} -xref: CAS:635-65-4 {source="ChemIDplus"} -xref: Gmelin:411033 {source="Gmelin"} -xref: HMDB:HMDB0000054 -xref: KEGG:C00486 -xref: KNApSAcK:C00029828 -xref: MetaCyc:BILIRUBIN -xref: PDBeChem:BLR -xref: PMID:12799017 {source="Europe PMC"} -xref: PMID:18442622 {source="Europe PMC"} -xref: PMID:23763371 {source="Europe PMC"} -xref: PMID:23768684 {source="Europe PMC"} -xref: PMID:30224965 {source="Europe PMC"} -xref: PMID:8605219 {source="Europe PMC"} -xref: PMID:9587403 {source="Europe PMC"} -xref: Reaxys:74376 {source="Reaxys"} -xref: Wikipedia:Bilirubin -is_a: CHEBI:35692 ! dicarboxylic acid -is_a: CHEBI:36735 ! biladienes -relationship: has_part CHEBI:142163 ! 24G7 epitope -relationship: is_conjugate_acid_of CHEBI:57977 ! bilirubin(2-) -relationship: RO:0000087 CHEBI:22586 ! has role antioxidant -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C33H36N4O6" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BPYKTIZUTYGOLE-IFADSCNNSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "584.673" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "584.26348" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC1=C(C=C)\\C(NC1=O)=C\\C1=C(C)C(CCC(O)=O)=C(CC2=C(CCC(O)=O)C(C)=C(N2)\\C=C2/NC(=O)C(C=C)=C2C)N1" xsd:string - -[Term] -id: CHEBI:16991 -name: deoxyribonucleic acid -namespace: chebi_ontology -alt_id: CHEBI:13302 -alt_id: CHEBI:21123 -alt_id: CHEBI:33698 -alt_id: CHEBI:4291 -def: "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms." [] -subset: 3_STAR -synonym: "(Deoxyribonucleotide)m" RELATED [KEGG_COMPOUND] -synonym: "(Deoxyribonucleotide)n" RELATED [KEGG_COMPOUND] -synonym: "(Deoxyribonucleotide)n+m" RELATED [KEGG_COMPOUND] -synonym: "Deoxyribonucleic acid" EXACT [KEGG_COMPOUND] -synonym: "deoxyribonucleic acids" EXACT IUPAC_NAME [IUPAC] -synonym: "deoxyribonucleic acids" RELATED [ChEBI] -synonym: "Desoxyribonukleinsaeure" RELATED [ChEBI] -synonym: "desoxyribose nucleic acid" RELATED [ChemIDplus] -synonym: "DNA" RELATED [UniProt] -synonym: "DNA" RELATED [KEGG_COMPOUND] -synonym: "DNA" RELATED [IUPAC] -synonym: "DNAn" RELATED [KEGG_COMPOUND] -synonym: "DNAn+1" RELATED [KEGG_COMPOUND] -synonym: "DNS" RELATED [ChEBI] -synonym: "thymus nucleic acid" RELATED [ChEBI] -xref: CAS:9007-49-2 {source="ChemIDplus"} -xref: CAS:9007-49-2 {source="KEGG COMPOUND"} -xref: KEGG:C00039 -is_a: CHEBI:33696 ! nucleic acid -relationship: has_part CHEBI:33793 ! canonical deoxyribonucleoside residue -relationship: has_part CHEBI:50298 ! canonical deoxyribonucleotide residue -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite - -[Term] -id: CHEBI:17026 -name: progesterone -namespace: chebi_ontology -alt_id: CHEBI:14896 -alt_id: CHEBI:18798 -alt_id: CHEBI:26269 -alt_id: CHEBI:439 -alt_id: CHEBI:45786 -alt_id: CHEBI:8453 -def: "A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species." [] -subset: 3_STAR -synonym: "(S)-4-Pregnene-3,20-dione" RELATED [KEGG_COMPOUND] -synonym: "(S)-Pregn-4-en-3,20-dione" RELATED [KEGG_COMPOUND] -synonym: "(S)-Progesterone" RELATED [KEGG_COMPOUND] -synonym: "17alpha-progesterone" RELATED [NIST_Chemistry_WebBook] -synonym: "4-Pregnene-3,20-dione" RELATED [KEGG_COMPOUND] -synonym: "Agolutin" RELATED [NIST_Chemistry_WebBook] -synonym: "Akrolutin" RELATED [ChEBI] -synonym: "corpus luteum hormone" RELATED [ChemIDplus] -synonym: "Crinone" RELATED [ChemIDplus] -synonym: "Delta(4)-pregnene-3,20-dione" RELATED [ChEBI] -synonym: "Gelbkoerperhormon" RELATED [ChEBI] -synonym: "luteohormone" RELATED [ChemIDplus] -synonym: "pregn-4-ene-3,20-dione" EXACT IUPAC_NAME [IUPAC] -synonym: "Progesteron" RELATED [ChEBI] -synonym: "PROGESTERONE" EXACT [PDBeChem] -synonym: "Progesterone" EXACT [KEGG_COMPOUND] -synonym: "progesterone" EXACT [UniProt] -xref: Beilstein:1915950 {source="Beilstein"} -xref: CAS:57-83-0 {source="KEGG COMPOUND"} -xref: CAS:57-83-0 {source="ChemIDplus"} -xref: CAS:57-83-0 {source="NIST Chemistry WebBook"} -xref: Drug_Central:2279 {source="DrugCentral"} -xref: DrugBank:DB00396 -xref: Gmelin:708590 {source="Gmelin"} -xref: HMDB:HMDB0001830 -xref: KEGG:C00410 -xref: KEGG:D00066 -xref: MetaCyc:PROGESTERONE -xref: PDBeChem:STR -xref: PMID:10438974 {source="Europe PMC"} -xref: PMID:9506942 {source="Europe PMC"} -xref: Reaxys:1915950 {source="Reaxys"} -xref: Wikipedia:Progesterone -is_a: CHEBI:36885 ! 20-oxo steroid -is_a: CHEBI:47909 ! 3-oxo-Delta(4) steroid -is_a: CHEBI:64600 ! C21-steroid hormone -relationship: has_parent_hydride CHEBI:8386 ! pregnane -relationship: RO:0000087 CHEBI:49323 ! has role contraceptive drug -relationship: RO:0000087 CHEBI:59826 ! has role progestin -relationship: RO:0000087 CHEBI:70709 ! has role progesterone receptor agonist -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C21H30O2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "RJKFOVLPORLFTN-LEKSSAKUSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "314.46170" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "314.22458" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])C(C)=O" xsd:string - -[Term] -id: CHEBI:17087 -name: ketone -namespace: chebi_ontology -alt_id: CHEBI:13427 -alt_id: CHEBI:13646 -alt_id: CHEBI:24974 -alt_id: CHEBI:6127 -alt_id: CHEBI:8742 -def: "A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H)." [] -subset: 3_STAR -synonym: "a ketone" RELATED [UniProt] -synonym: "cetone" RELATED [ChEBI] -synonym: "Keton" RELATED [ChEBI] -synonym: "Ketone" EXACT [KEGG_COMPOUND] -synonym: "ketones" EXACT IUPAC_NAME [IUPAC] -synonym: "ketones" RELATED [ChEBI] -synonym: "R-CO-R'" RELATED [KEGG_COMPOUND] -xref: KEGG:C01450 -xref: Wikipedia:Ketone -is_a: CHEBI:36586 ! carbonyl compound -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "COR2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "28.010" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "27.99491" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]C([*])=O" xsd:string - -[Term] -id: CHEBI:17089 -name: glycoprotein -namespace: chebi_ontology -alt_id: CHEBI:14349 -alt_id: CHEBI:5481 -alt_id: CHEBI:5493 -def: "A compound in which a carbohydrate component is covalently bound to a protein component." [] -subset: 3_STAR -synonym: "a glycoprotein" RELATED [UniProt] -synonym: "glicoproteina" RELATED [ChEBI] -synonym: "glicoproteinas" RELATED [ChEBI] -synonym: "Glycoprotein" EXACT [KEGG_COMPOUND] -synonym: "glycoproteine" RELATED [ChEBI] -synonym: "glycoproteines" RELATED [ChEBI] -synonym: "glycoproteins" EXACT IUPAC_NAME [IUPAC] -synonym: "Glykoprotein" RELATED [ChEBI] -synonym: "Glykoproteine" RELATED [ChEBI] -xref: KEGG:C00326 -is_a: CHEBI:33837 ! conjugated protein -is_a: CHEBI:63299 ! carbohydrate derivative - -[Term] -id: CHEBI:17234 -name: glucose -namespace: chebi_ontology -alt_id: CHEBI:14313 -alt_id: CHEBI:24277 -alt_id: CHEBI:33929 -alt_id: CHEBI:5418 -def: "An aldohexose used as a source of energy and metabolic intermediate." [] -subset: 3_STAR -synonym: "DL-glucose" RELATED [ChEBI] -synonym: "Glc" RELATED [JCBN] -synonym: "gluco-hexose" EXACT IUPAC_NAME [IUPAC] -synonym: "Glucose" EXACT [KEGG_COMPOUND] -synonym: "glucose" EXACT IUPAC_NAME [IUPAC] -synonym: "Glukose" RELATED [ChEBI] -xref: CAS:50-99-7 {source="KEGG COMPOUND"} -xref: KEGG:C00293 -xref: Wikipedia:Glucose -is_a: CHEBI:33917 ! aldohexose -relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H12O6" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "180.15588" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "180.06339" xsd:string - -[Term] -id: CHEBI:17347 -name: testosterone -namespace: chebi_ontology -alt_id: CHEBI:15214 -alt_id: CHEBI:26883 -alt_id: CHEBI:45798 -alt_id: CHEBI:9461 -def: "An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5.." [] -subset: 3_STAR -synonym: "17beta-Hydroxy-4-androsten-3-one" RELATED [KEGG_COMPOUND] -synonym: "17beta-hydroxy-4-androsten-3-one" RELATED [ChEBI] -synonym: "17beta-hydroxyandrost-4-en-3-one" EXACT IUPAC_NAME [IUPAC] -synonym: "4-androsten-17beta-ol-3-one" RELATED [NIST_Chemistry_WebBook] -synonym: "Androderm" RELATED [ChemIDplus] -synonym: "Testosteron" RELATED [ChemIDplus] -synonym: "testosterona" RELATED INN [ChemIDplus] -synonym: "TESTOSTERONE" EXACT [PDBeChem] -synonym: "Testosterone" EXACT [KEGG_COMPOUND] -synonym: "testosterone" EXACT [UniProt] -synonym: "testosterone" RELATED INN [ChemIDplus] -synonym: "testosteronum" RELATED INN [ChemIDplus] -xref: Beilstein:1915399 {source="Beilstein"} -xref: Beilstein:3653705 {source="Beilstein"} -xref: CAS:58-22-0 {source="NIST Chemistry WebBook"} -xref: CAS:58-22-0 {source="ChemIDplus"} -xref: CAS:58-22-0 {source="KEGG COMPOUND"} -xref: Drug_Central:2607 {source="DrugCentral"} -xref: DrugBank:DB00624 -xref: Gmelin:538843 {source="Gmelin"} -xref: HMDB:HMDB0000234 -xref: KEGG:C00535 -xref: KEGG:D00075 -xref: KNApSAcK:C00003675 -xref: LIPID_MAPS_instance:LMST02020002 {source="LIPID MAPS"} -xref: PDBeChem:TES -xref: PMID:10438974 {source="Europe PMC"} -xref: PMID:11786693 {source="Europe PMC"} -xref: PMID:18900503 {source="Europe PMC"} -xref: PMID:24498482 {source="Europe PMC"} -xref: Reaxys:1915399 {source="Reaxys"} -xref: Wikipedia:Testosterone -is_a: CHEBI:131621 ! C19-steroid -is_a: CHEBI:35343 ! 17beta-hydroxy steroid -is_a: CHEBI:47909 ! 3-oxo-Delta(4) steroid -is_a: CHEBI:50402 ! androstanoid -relationship: RO:0000087 CHEBI:50113 ! has role androgen -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C19H28O2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "MUMGGOZAMZWBJJ-DYKIIFRCSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "288.42440" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "288.20893" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@@H](O)CC[C@@]21[H]" xsd:string - -[Term] -id: CHEBI:17478 -name: aldehyde -namespace: chebi_ontology -alt_id: CHEBI:13432 -alt_id: CHEBI:13753 -alt_id: CHEBI:13805 -alt_id: CHEBI:13806 -alt_id: CHEBI:22291 -alt_id: CHEBI:2554 -alt_id: CHEBI:8750 -def: "A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group." [] -subset: 3_STAR -synonym: "aldehido" RELATED [ChEBI] -synonym: "aldehidos" RELATED [ChEBI] -synonym: "Aldehyd" RELATED [ChEBI] -synonym: "Aldehyde" EXACT [KEGG_COMPOUND] -synonym: "aldehyde" EXACT [ChEBI] -synonym: "aldehyde" EXACT IUPAC_NAME [IUPAC] -synonym: "aldehydes" EXACT IUPAC_NAME [IUPAC] -synonym: "aldehydes" RELATED [ChEBI] -synonym: "aldehydum" RELATED [ChEBI] -synonym: "an aldehyde" RELATED [UniProt] -synonym: "RC(=O)H" RELATED [IUPAC] -synonym: "RCHO" RELATED [KEGG_COMPOUND] -xref: KEGG:C00071 -is_a: CHEBI:36586 ! carbonyl compound -relationship: has_part CHEBI:42485 ! formyl group -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CHOR" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "29.01800" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "29.00274" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]C([*])=O" xsd:string - -[Term] -id: CHEBI:17544 -name: hydrogencarbonate -namespace: chebi_ontology -alt_id: CHEBI:13363 -alt_id: CHEBI:22863 -alt_id: CHEBI:40961 -alt_id: CHEBI:5589 -def: "The carbon oxoanion resulting from the removal of a proton from carbonic acid." [] -subset: 3_STAR -synonym: "[CO2(OH)](-)" RELATED [IUPAC] -synonym: "Acid carbonate" RELATED [KEGG_COMPOUND] -synonym: "Bicarbonate" RELATED [KEGG_COMPOUND] -synonym: "BICARBONATE ION" RELATED [PDBeChem] -synonym: "HCO3(-)" RELATED [IUPAC] -synonym: "HCO3-" RELATED [KEGG_COMPOUND] -synonym: "hydrogen carbonate" RELATED [PDBeChem] -synonym: "hydrogen(trioxidocarbonate)(1-)" EXACT IUPAC_NAME [IUPAC] -synonym: "Hydrogencarbonate" EXACT [KEGG_COMPOUND] -synonym: "hydrogencarbonate" EXACT [UniProt] -synonym: "hydrogencarbonate" EXACT IUPAC_NAME [IUPAC] -synonym: "hydrogencarbonate(1-)" EXACT IUPAC_NAME [IUPAC] -synonym: "hydrogentrioxocarbonate(1-)" EXACT IUPAC_NAME [IUPAC] -synonym: "hydrogentrioxocarbonate(IV)" EXACT IUPAC_NAME [IUPAC] -synonym: "hydroxidodioxidocarbonate(1-)" EXACT IUPAC_NAME [IUPAC] -xref: Beilstein:3903504 {source="Beilstein"} -xref: CAS:71-52-3 {source="ChemIDplus"} -xref: Gmelin:49249 {source="Gmelin"} -xref: HMDB:HMDB0000595 -xref: KEGG:C00288 -xref: MetaCyc:HCO3 -xref: PDBeChem:BCT -xref: PMID:17215880 {source="Europe PMC"} -xref: PMID:17505962 {source="Europe PMC"} -xref: PMID:18439416 {source="Europe PMC"} -xref: PMID:28732801 {source="Europe PMC"} -xref: PMID:29150416 {source="Europe PMC"} -xref: PMID:29460248 {source="Europe PMC"} -xref: PMID:29466234 {source="Europe PMC"} -xref: PMID:4208463 {source="Europe PMC"} -xref: Wikipedia:Bicarbonate -is_a: CHEBI:35604 ! carbon oxoanion -relationship: is_conjugate_acid_of CHEBI:41609 ! carbonate -relationship: is_conjugate_base_of CHEBI:28976 ! carbonic acid -relationship: RO:0000087 CHEBI:23357 ! has role cofactor -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite -relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-M" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "61.01684" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.99312" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC([O-])=O" xsd:string - -[Term] -id: CHEBI:176497 -name: geroprotector -namespace: chebi_ontology -def: "Any compound that supports healthy aging, slows the biological aging process, or extends lifespan." [] -subset: 3_STAR -synonym: "anti-aging agent" RELATED [ChEBI] -synonym: "anti-aging agents" RELATED [ChEBI] -synonym: "anti-aging drug" RELATED [ChEBI] -synonym: "anti-aging drugs" RELATED [ChEBI] -synonym: "geroprotective agent" RELATED [ChEBI] -synonym: "geroprotective agents" RELATED [ChEBI] -synonym: "geroprotectors" RELATED [ChEBI] -xref: PMID:23372317 {source="Europe PMC"} -xref: PMID:28580190 {source="Europe PMC"} -xref: PMID:30885572 {source="Europe PMC"} -xref: PMID:33144142 {source="Europe PMC"} -xref: PMID:33973253 {source="Europe PMC"} -xref: PMID:34606237 {source="Europe PMC"} -xref: Wikipedia:Geroprotector -is_a: CHEBI:50267 ! protective agent - -[Term] -id: CHEBI:177917 -name: phenolic steroid -namespace: chebi_ontology -subset: 2_STAR -synonym: "a phenolic steroid" RELATED [UniProt] -xref: KEGG:C02453 {source="SUBMITTER"} -xref: MetaCyc:PHENOLIC-STEROID {source="SUBMITTER"} -is_a: CHEBI:33853 ! phenols -is_a: CHEBI:36834 ! 3-hydroxy steroid -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C18H24O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C18H24O/c1-18-9-2-3-17(18)16-6-4-12-11-13(19)5-7-14(12)15(16)8-10-18/h5,7,11,15-17,19H,2-4,6,8-10H2,1H3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "HJKVPZJVBHWFCQ-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "256.389" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "256.18272" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1=C2C(CCC3C4CCCC4(CCC32)C)=CC(=C1)O" xsd:string - -[Term] -id: CHEBI:17891 -name: donor -namespace: chebi_ontology -alt_id: CHEBI:14202 -alt_id: CHEBI:4697 -def: "A molecular entity that can transfer (\"donate\") an electron, a pair of electrons, an atom or a group to another molecular entity." [] -subset: 3_STAR -synonym: "Donator" RELATED [ChEBI] -synonym: "donneur" RELATED [ChEBI] -synonym: "Donor" EXACT [KEGG_COMPOUND] -xref: KEGG:C01351 -is_a: CHEBI:51086 ! chemical role - -[Term] -id: CHEBI:17968 -name: butyrate -namespace: chebi_ontology -alt_id: CHEBI:13924 -alt_id: CHEBI:22946 -def: "A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group." [] -subset: 3_STAR -synonym: "1-butanoate" RELATED [ChEBI] -synonym: "1-butyrate" RELATED [ChEBI] -synonym: "1-propanecarboxylate" RELATED [ChEBI] -synonym: "butanate" RELATED [ChEBI] -synonym: "butanoate" EXACT IUPAC_NAME [IUPAC] -synonym: "butanoate" RELATED [ChEBI] -synonym: "butanoate" RELATED [UniProt] -synonym: "butanoic acid, ion(1-)" RELATED [ChemIDplus] -synonym: "butyrate" EXACT [IUPAC] -synonym: "CH3-[CH2]2-COO(-)" RELATED [IUPAC] -synonym: "n-butanoate" RELATED [ChEBI] -synonym: "n-butyrate" RELATED [ChemIDplus] -synonym: "propanecarboxylate" RELATED [ChEBI] -synonym: "propylformate" RELATED [ChEBI] -xref: Beilstein:3601060 {source="Beilstein"} -xref: CAS:461-55-2 {source="ChemIDplus"} -xref: Gmelin:324289 {source="Gmelin"} -xref: KEGG:C00246 -xref: MetaCyc:BUTYRIC_ACID -xref: PMID:17190852 {source="Europe PMC"} -xref: PMID:7496326 {source="Europe PMC"} -xref: Reaxys:3601060 {source="Reaxys"} -xref: UM-BBD_compID:c0035 {source="UM-BBD"} -is_a: CHEBI:78115 ! fatty acid anion 4:0 -relationship: is_conjugate_base_of CHEBI:30772 ! butyric acid -relationship: RO:0000087 CHEBI:61115 ! has role EC 3.5.1.98 (histone deacetylase) inhibitor -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H7O2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)/p-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "FERIUCNNQQJTOY-UHFFFAOYSA-M" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "87.09718" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "87.04515" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCCC([O-])=O" xsd:string [Term] id: CHEBI:18059 -name: lipid namespace: chebi_ontology -alt_id: CHEBI:14517 -alt_id: CHEBI:25054 -alt_id: CHEBI:6486 def: "'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids." [ANON:ANON] -subset: 3_STAR -synonym: "Lipid" EXACT [KEGG_COMPOUND] synonym: "Lipid" EXACT [KEGG COMPOUND:] synonym: "lipid" EXACT [UniProt:] synonym: "lipids" EXACT IUPAC_NAME [IUPAC:] -synonym: "lipids" EXACT IUPAC_NAME [IUPAC] -xref: KEGG:C01356 -is_a: CHEBI:50860 ! organic molecular entity - -[Term] -id: CHEBI:18085 -name: glycosaminoglycan -namespace: chebi_ontology -alt_id: CHEBI:14361 -alt_id: CHEBI:24398 -alt_id: CHEBI:5495 -def: "Any polysaccharide containing a substantial proportion of aminomonosaccharide residues." [] -subset: 3_STAR -synonym: "glicosaminoglicano" RELATED [IUPAC] -synonym: "Glycosaminoglycan" EXACT [KEGG_COMPOUND] -synonym: "glycosaminoglycan" EXACT IUPAC_NAME [IUPAC] -synonym: "glycosaminoglycane" RELATED [IUPAC] -synonym: "glycosaminoglycans" RELATED [ChEBI] -synonym: "Glykosaminoglykan" RELATED [ChEBI] -xref: KEGG:C02545 -xref: Wikipedia:Glycosaminoglycan -is_a: CHEBI:22506 ! aminoglycan - -[Term] -id: CHEBI:18133 -name: hexose -namespace: chebi_ontology -alt_id: CHEBI:14399 -alt_id: CHEBI:24590 -alt_id: CHEBI:5709 -def: "Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose)." [] -subset: 3_STAR -synonym: "Hexose" EXACT [KEGG_COMPOUND] -synonym: "hexoses" RELATED [ChEBI] -synonym: "WURCS=2.0/1,1,0/[axxxxh-1x_1-5_2*NCC/3=O]/1/" RELATED [GlyTouCan] -xref: GlyGen:G70994MS -xref: GlyTouCan:G70994MS -xref: KEGG:C00738 -is_a: CHEBI:35381 ! monosaccharide - -[Term] -id: CHEBI:18154 -name: polysaccharide -namespace: chebi_ontology -alt_id: CHEBI:14864 -alt_id: CHEBI:26205 -alt_id: CHEBI:8322 -def: "A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues." [] -subset: 3_STAR -synonym: "Glycan" RELATED [KEGG_COMPOUND] -synonym: "Glycane" RELATED [ChEBI] -synonym: "glycans" RELATED [IUPAC] -synonym: "Glykan" RELATED [ChEBI] -synonym: "Glykane" RELATED [ChEBI] -synonym: "polisacarido" RELATED [ChEBI] -synonym: "polisacaridos" RELATED [IUPAC] -synonym: "Polysaccharide" EXACT [KEGG_COMPOUND] -synonym: "polysaccharides" EXACT IUPAC_NAME [IUPAC] -xref: KEGG:C00420 -is_a: CHEBI:16646 ! carbohydrate -is_a: CHEBI:167559 ! glycan -is_a: CHEBI:33694 ! biomacromolecule - -[Term] -id: CHEBI:18237 -name: glutamic acid -namespace: chebi_ontology -alt_id: CHEBI:24314 -alt_id: CHEBI:5431 -def: "An alpha-amino acid that has formula C5H9NO4." [ANON:ANON] -def: "An alpha-amino acid that is glutaric acid bearing a single amino substituent at position 2." [] -subset: 3_STAR -synonym: "2-Aminoglutaric acid" RELATED [KEGG_COMPOUND] -synonym: "2-Aminoglutaric acid" RELATED [KEGG COMPOUND:] -synonym: "2-aminopentanedioic acid" EXACT IUPAC_NAME [IUPAC:] -synonym: "2-aminopentanedioic acid" EXACT IUPAC_NAME [IUPAC] -synonym: "C5H9NO4" RELATED FORMULA [KEGG COMPOUND:] -synonym: "DL-Glutamic acid" RELATED [KEGG_DRUG] -synonym: "DL-Glutaminic acid" RELATED [KEGG_COMPOUND] -synonym: "E" RELATED [ChEBI] -synonym: "Glu" RELATED [ChEBI] -synonym: "Glutamate" RELATED [KEGG_COMPOUND] -synonym: "Glutamic acid" EXACT [KEGG_COMPOUND] -synonym: "glutamic acid" EXACT IUPAC_NAME [IUPAC:] -synonym: "glutamic acid" EXACT IUPAC_NAME [IUPAC] -synonym: "Glutaminic acid" RELATED [KEGG COMPOUND:] -synonym: "Glutaminic acid" RELATED [KEGG_COMPOUND] -synonym: "Glutaminsaeure" RELATED [ChEBI:] -synonym: "Glutaminsaeure" RELATED [ChEBI] -synonym: "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)" RELATED InChI [ChEBI:] -synonym: "InChIKey=WHUUTDBJXJRKMK-UHFFFAOYSA-N" RELATED InChIKey [ChEBI:] -synonym: "NC(CCC(O)=O)C(O)=O" RELATED SMILES [ChEBI:] -xref: Beilstein:1723799 {source="Beilstein"} -xref: CAS:617-65-2 {source="ChemIDplus"} -xref: CAS:617-65-2 {source="NIST Chemistry WebBook"} -xref: CAS:617-65-2 {source="KEGG COMPOUND"} -xref: Gmelin:101971 {source="Gmelin"} -xref: KEGG:C00302 -xref: KEGG:D04341 -xref: KNApSAcK:C00001358 -xref: KNApSAcK:C00019577 -xref: PMID:15739367 {source="Europe PMC"} -xref: PMID:17190852 {source="Europe PMC"} -xref: PMID:24616376 {source="Europe PMC"} -xref: PMID:24984001 {source="Europe PMC"} -xref: Reaxys:1723799 {source="Reaxys"} -xref: Wikipedia:Glutamic_acid -is_a: CHEBI:26167 ! polar amino acid -is_a: CHEBI:33704 ! alpha-amino acid -relationship: has_part CHEBI:50329 ! 2-carboxyethyl group -relationship: is_conjugate_acid_of CHEBI:14321 ! glutamate(1-) -relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H9NO4" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "WHUUTDBJXJRKMK-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "147.12930" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "147.05316" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(CCC(O)=O)C(O)=O" xsd:string - -[Term] -id: CHEBI:18243 -name: dopamine -namespace: chebi_ontology -alt_id: CHEBI:11695 -alt_id: CHEBI:11930 -alt_id: CHEBI:14203 -alt_id: CHEBI:1764 -alt_id: CHEBI:23886 -alt_id: CHEBI:43686 -def: "Catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group." [ANON:ANON] -subset: 3_STAR -synonym: "2-(3,4-Dihydroxyphenyl)ethylamine" RELATED [KEGG COMPOUND:] -synonym: "2-(3,4-Dihydroxyphenyl)ethylamine" RELATED [KEGG_COMPOUND] -synonym: "2-(3,4-dihydroxyphenyl)ethylamine" RELATED [ChEBI] -synonym: "2-(3,4-dihydroxyphenyl)ethylamine" RELATED [ChEBI:] -synonym: "3,4-Dihydroxyphenethylamine" RELATED [KEGG_COMPOUND] -synonym: "3,4-Dihydroxyphenethylamine" RELATED [KEGG COMPOUND:] -synonym: "3-Hydroxytyramine" RELATED [ChemIDplus] -synonym: "3-Hydroxytyramine" RELATED [ChemIDplus:] -synonym: "4-(2-Aminoethyl)-1,2-benzenediol" RELATED [KEGG_COMPOUND] -synonym: "4-(2-Aminoethyl)-1,2-benzenediol" RELATED [KEGG COMPOUND:] -synonym: "4-(2-aminoethyl)-1,2-benzenediol" RELATED [ChEBI] -synonym: "4-(2-aminoethyl)-1,2-benzenediol" RELATED [ChEBI:] -synonym: "4-(2-Aminoethyl)benzene-1,2-diol" RELATED [KEGG_COMPOUND] -synonym: "4-(2-Aminoethyl)benzene-1,2-diol" RELATED [KEGG COMPOUND:] -synonym: "4-(2-aminoethyl)benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC] -synonym: "4-(2-aminoethyl)benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC:] -synonym: "4-(2-aminoethyl)catechol" RELATED [ChemIDplus:] -synonym: "4-(2-aminoethyl)catechol" RELATED [ChemIDplus] -synonym: "4-(2-aminoethyl)pyrocatechol" RELATED [ChemIDplus] -synonym: "4-(2-aminoethyl)pyrocatechol" RELATED [ChemIDplus:] -synonym: "C8H11NO2" RELATED FORMULA [KEGG COMPOUND:] -synonym: "Deoxyepinephrine" RELATED [DrugBank:] -synonym: "Deoxyepinephrine" RELATED [DrugBank] -synonym: "dopamina" RELATED INN [ChemIDplus:] -synonym: "dopamina" RELATED INN [ChemIDplus] -synonym: "Dopamine" EXACT [KEGG_COMPOUND] -synonym: "Dopamine" EXACT [KEGG COMPOUND:] -synonym: "dopamine" RELATED INN [ChEBI:] -synonym: "dopamine" RELATED INN [ChEBI] -synonym: "dopaminum" RELATED INN [ChemIDplus] -synonym: "dopaminum" RELATED INN [ChemIDplus:] -synonym: "Hydroxytyramin" RELATED [DrugBank:] -synonym: "Hydroxytyramin" RELATED [DrugBank] -synonym: "InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2" RELATED InChI [ChEBI:] -synonym: "InChIKey=VYFYYTLLBUKUHU-UHFFFAOYSA-N" RELATED InChIKey [ChEBI:] -synonym: "NCCc1ccc(O)c(O)c1" RELATED SMILES [ChEBI:] -xref: CAS:51-61-6 {source="ChemIDplus"} -xref: Drug_Central:947 {source="DrugCentral"} -xref: DrugBank:DB00988 -xref: HMDB:HMDB0000073 -xref: KEGG:C03758 -xref: KEGG:D07870 -xref: KNApSAcK:C00001408 -xref: LINCS:LSM-4630 -xref: MetaCyc:DOPAMINE -xref: PMID:10629745 {source="Europe PMC"} -xref: PMID:11149432 {source="Europe PMC"} -xref: PMID:9422813 {source="Europe PMC"} -xref: Reaxys:1072822 {source="Reaxys"} -xref: Wikipedia:Dopamine -is_a: CHEBI:33567 ! catecholamine -relationship: is_conjugate_base_of CHEBI:59905 ! dopaminium(1+) -relationship: RO:0000087 CHEBI:35522 ! has role beta-adrenergic agonist -relationship: RO:0000087 CHEBI:35524 ! has role sympathomimetic agent -relationship: RO:0000087 CHEBI:38147 ! has role cardiotonic drug -relationship: RO:0000087 CHEBI:48560 ! has role dopaminergic agent -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H11NO2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "VYFYYTLLBUKUHU-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "153.17840" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "153.07898" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "NCCc1ccc(O)c(O)c1" xsd:string - -[Term] -id: CHEBI:18248 -name: iron atom -namespace: chebi_ontology -alt_id: CHEBI:13322 -alt_id: CHEBI:24872 -alt_id: CHEBI:5974 -def: "An iron group element atom that has atomic number 26." [] -subset: 3_STAR -synonym: "26Fe" RELATED [IUPAC] -synonym: "Eisen" RELATED [ChEBI] -synonym: "Fe" RELATED [UniProt] -synonym: "Fe" RELATED [IUPAC] -synonym: "fer" RELATED [ChEBI] -synonym: "ferrum" RELATED [IUPAC] -synonym: "hierro" RELATED [ChEBI] -synonym: "Iron" RELATED [KEGG_COMPOUND] -synonym: "iron" EXACT IUPAC_NAME [IUPAC] -synonym: "iron" RELATED [ChEBI] -xref: CAS:7439-89-6 {source="ChemIDplus"} -xref: CAS:7439-89-6 {source="NIST Chemistry WebBook"} -xref: CAS:7439-89-6 {source="KEGG COMPOUND"} -xref: DrugBank:DB01592 -xref: HMDB:HMDB0015531 -xref: KEGG:C00023 -xref: Reaxys:4122945 {source="Reaxys"} -xref: WebElements:Fe -is_a: CHEBI:33356 ! iron group element atom -relationship: RO:0000087 CHEBI:27027 ! has role micronutrient -relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "Fe" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Fe" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "XEEYBQQBJWHFJM-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "55.84500" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "55.93494" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Fe]" xsd:string - -[Term] -id: CHEBI:18282 -name: nucleobase -namespace: chebi_ontology -alt_id: CHEBI:13873 -alt_id: CHEBI:25598 -alt_id: CHEBI:2995 -def: "That part of DNA or RNA that may be involved in pairing." [] -subset: 3_STAR -synonym: "Base" RELATED [KEGG_COMPOUND] -synonym: "nucleobases" RELATED [ChEBI] -xref: KEGG:C00701 -xref: Wikipedia:Nucleobase -is_a: CHEBI:38101 ! organonitrogen heterocyclic compound - -[Term] -id: CHEBI:18295 -name: histamine -namespace: chebi_ontology -alt_id: CHEBI:14401 -alt_id: CHEBI:24596 -alt_id: CHEBI:43187 -alt_id: CHEBI:817 -def: "A member of the class of imidazoles that is 1H-imidazole substituted at position C-4 by a 2-aminoethyl group." [] -def: "An aralkylamine that has formula C5H9N3." [ANON:ANON] -subset: 3_STAR -synonym: "1H-Imidazole-4-ethanamine" RELATED [KEGG COMPOUND:] -synonym: "1H-Imidazole-4-ethanamine" RELATED [KEGG_COMPOUND] -synonym: "2-(1H-imidazol-4-yl)ethanamine" EXACT IUPAC_NAME [IUPAC:] -synonym: "2-(1H-imidazol-4-yl)ethanamine" EXACT IUPAC_NAME [IUPAC] -synonym: "2-(4-Imidazolyl)ethylamine" RELATED [KEGG COMPOUND:] -synonym: "2-(4-Imidazolyl)ethylamine" RELATED [KEGG_COMPOUND] -synonym: "C5H9N3" RELATED FORMULA [KEGG COMPOUND:] -synonym: "HISTAMINE" EXACT [PDBeChem:] -synonym: "HISTAMINE" EXACT [PDBeChem] -synonym: "Histamine" EXACT [KEGG COMPOUND:] -synonym: "Histamine" EXACT [KEGG_COMPOUND] -synonym: "InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)" RELATED InChI [ChEBI:] -synonym: "InChIKey=NTYJJOPFIAHURM-UHFFFAOYSA-N" RELATED InChIKey [ChEBI:] -synonym: "NCCc1c[nH]cn1" RELATED SMILES [ChEBI:] -xref: Beilstein:2012 {source="Beilstein"} -xref: CAS:51-45-6 {source="NIST Chemistry WebBook"} -xref: CAS:51-45-6 {source="ChemIDplus"} -xref: CAS:51-45-6 {source="KEGG COMPOUND"} -xref: Drug_Central:1375 {source="DrugCentral"} -xref: Gmelin:2968 {source="Gmelin"} -xref: HMDB:HMDB0000870 -xref: KEGG:C00388 -xref: KEGG:D08040 -xref: KNApSAcK:C00001414 -xref: MetaCyc:HISTAMINE -xref: PDBeChem:HSM -xref: PMID:16399866 {source="Europe PMC"} -xref: PMID:19547708 {source="Europe PMC"} -xref: PMID:19843401 {source="Europe PMC"} -xref: PMID:22770225 {source="Europe PMC"} -xref: PMID:24101735 {source="Europe PMC"} -xref: Reaxys:2012 {source="Reaxys"} -xref: Wikipedia:Histamine -is_a: CHEBI:24780 ! imidazoles -is_a: CHEBI:64365 ! aralkylamino compound -relationship: is_conjugate_base_of CHEBI:58432 ! histaminium -relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H9N3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NTYJJOPFIAHURM-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "111.14518" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "111.07965" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "NCCc1c[nH]cn1" xsd:string - -[Term] -id: CHEBI:18310 -name: alkane -namespace: chebi_ontology -alt_id: CHEBI:13435 -alt_id: CHEBI:22317 -alt_id: CHEBI:2576 -def: "An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms." [] -subset: 3_STAR -synonym: "alcane" RELATED [IUPAC] -synonym: "alcanes" RELATED [IUPAC] -synonym: "alcano" RELATED [IUPAC] -synonym: "alcanos" RELATED [IUPAC] -synonym: "Alkan" RELATED [ChEBI] -synonym: "Alkane" EXACT [KEGG_COMPOUND] -synonym: "alkane" EXACT IUPAC_NAME [IUPAC] -synonym: "alkanes" EXACT IUPAC_NAME [IUPAC] -synonym: "an alkane" RELATED [UniProt] -synonym: "RH" RELATED [KEGG_COMPOUND] -xref: KEGG:C01371 -is_a: CHEBI:24632 ! hydrocarbon -is_a: CHEBI:33653 ! aliphatic compound -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CH3R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "15.035" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.02348" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C[*]" xsd:string - -[Term] -id: CHEBI:18357 -name: (R)-noradrenaline -namespace: chebi_ontology -alt_id: CHEBI:1 -alt_id: CHEBI:14668 -alt_id: CHEBI:25592 -alt_id: CHEBI:258884 -alt_id: CHEBI:43725 -def: "The R-enantiomer of noradrenaline." [] -subset: 3_STAR -synonym: "(-)-arterenol" RELATED [ChemIDplus] -synonym: "(-)-noradrenaline" RELATED [IUPHAR] -synonym: "(-)-norepinephrine" RELATED [ChemIDplus] -synonym: "(R)-(-)-norepinephrine" RELATED [ChemIDplus] -synonym: "(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol" RELATED [ChemIDplus] -synonym: "(R)-norepinephrine" RELATED [ChemIDplus] -synonym: "4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol" RELATED [KEGG_COMPOUND] -synonym: "4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC] -synonym: "Arterenol" RELATED [KEGG_COMPOUND] -synonym: "L-Noradrenaline" RELATED [KEGG_COMPOUND] -synonym: "L-NOREPINEPHRINE" RELATED [PDBeChem] -synonym: "Noradrenaline" RELATED [KEGG_COMPOUND] -synonym: "norepinefrina" RELATED INN [ChEBI] -synonym: "Norepinephrine" RELATED [KEGG_COMPOUND] -synonym: "norepinephrine" RELATED INN [ChemIDplus] -synonym: "norepinephrine" RELATED INN [WHO_MedNet] -synonym: "norepinephrinum" RELATED INN [ChEBI] -xref: Beilstein:2804840 {source="Beilstein"} -xref: Beilstein:4231961 {source="ChemIDplus"} -xref: CAS:51-41-2 {source="ChemIDplus"} -xref: CAS:51-41-2 {source="KEGG COMPOUND"} -xref: Drug_Central:1960 {source="DrugCentral"} -xref: DrugBank:DB00368 -xref: HMDB:HMDB0000216 -xref: KEGG:C00547 -xref: KEGG:D00076 -xref: KNApSAcK:C00001424 -xref: PDBeChem:LNR -xref: Reaxys:2804840 {source="Reaxys"} -xref: Wikipedia:Norepinephrine -is_a: CHEBI:33569 ! noradrenaline -relationship: is_conjugate_base_of CHEBI:72587 ! (R)-noradrenaline(1+) -relationship: is_enantiomer_of CHEBI:33571 ! (S)-noradrenaline -relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter -relationship: RO:0000087 CHEBI:35524 ! has role sympathomimetic agent -relationship: RO:0000087 CHEBI:35569 ! has role alpha-adrenergic agonist -relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H11NO3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-QMMMGPOBSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "169.17780" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "169.07389" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC[C@H](O)c1ccc(O)c(O)c1" xsd:string - -[Term] -id: CHEBI:18367 -name: phosphate(3-) -namespace: chebi_ontology -alt_id: CHEBI:14791 -alt_id: CHEBI:45024 -alt_id: CHEBI:7793 -def: "A phosphate ion that is the conjugate base of hydrogenphosphate." [] -subset: 3_STAR -synonym: "[PO4](3-)" RELATED [IUPAC] -synonym: "Orthophosphate" RELATED [KEGG_COMPOUND] -synonym: "Phosphate" RELATED [KEGG_COMPOUND] -synonym: "phosphate" EXACT IUPAC_NAME [IUPAC] -synonym: "PHOSPHATE ION" RELATED [PDBeChem] -synonym: "PO4(3-)" RELATED [IUPAC] -synonym: "tetraoxidophosphate(3-)" EXACT IUPAC_NAME [IUPAC] -synonym: "tetraoxophosphate(3-)" EXACT IUPAC_NAME [IUPAC] -synonym: "tetraoxophosphate(V)" EXACT IUPAC_NAME [IUPAC] -xref: Beilstein:3903772 {source="Beilstein"} -xref: CAS:14265-44-2 {source="KEGG COMPOUND"} -xref: CAS:14265-44-2 {source="ChemIDplus"} -xref: Gmelin:1997 {source="Gmelin"} -xref: KEGG:C00009 -xref: PDBeChem:PO4 {source="ChEBI"} -xref: Reaxys:3903772 {source="Reaxys"} -is_a: CHEBI:35780 ! phosphate ion -is_a: CHEBI:79387 ! trivalent inorganic anion -relationship: is_conjugate_base_of CHEBI:43474 ! hydrogenphosphate -property_value: http://purl.obolibrary.org/obo/chebi/charge "-3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "O4P" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-K" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "94.97136" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "94.95507" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]P([O-])([O-])=O" xsd:string - -[Term] -id: CHEBI:18421 -name: superoxide -namespace: chebi_ontology -alt_id: CHEBI:15143 -alt_id: CHEBI:26839 -alt_id: CHEBI:7710 -subset: 3_STAR -synonym: "(O2)(.-)" RELATED [IUPAC] -synonym: "Dioxid(1-)" RELATED [ChEBI] -synonym: "dioxidanidyl" EXACT IUPAC_NAME [IUPAC] -synonym: "dioxide(.1-)" EXACT IUPAC_NAME [IUPAC] -synonym: "dioxide(1-)" RELATED [IUPAC] -synonym: "hiperoxido" RELATED [ChEBI] -synonym: "Hyperoxid" RELATED [ChEBI] -synonym: "hyperoxide" RELATED [IUPAC] -synonym: "O2(-)" RELATED [IUPAC] -synonym: "O2(.-)" RELATED [IUPAC] -synonym: "O2-" RELATED [KEGG_COMPOUND] -synonym: "O2.-" RELATED [KEGG_COMPOUND] -synonym: "superoxide" EXACT [IUPAC] -synonym: "superoxide" EXACT [UniProt] -synonym: "Superoxide anion" RELATED [KEGG_COMPOUND] -synonym: "superoxide anion radical" RELATED [ChemIDplus] -synonym: "superoxide radical" RELATED [ChEBI] -synonym: "superoxide radical anion" RELATED [ChEBI] -synonym: "superoxido" RELATED [ChEBI] -synonym: "superoxyde" RELATED [ChEBI] -xref: CAS:11062-77-4 {source="ChemIDplus"} -xref: CAS:11062-77-4 {source="NIST Chemistry WebBook"} -xref: Chemspider:4514331 -xref: FooDB:FDB022880 -xref: Gmelin:487 {source="Gmelin"} -xref: HMDB:HMDB0002168 -xref: KEGG:C00704 -xref: MetaCyc:SUPER-OXIDE -xref: PDBeChem:2FK -xref: PMID:10440226 {source="Europe PMC"} -xref: PMID:10523323 {source="Europe PMC"} -xref: PMID:10588368 {source="Europe PMC"} -xref: PMID:11008114 {source="Europe PMC"} -xref: PMID:11333112 {source="Europe PMC"} -xref: PMID:11485972 {source="Europe PMC"} -xref: PMID:12097818 {source="Europe PMC"} -xref: PMID:12137408 {source="Europe PMC"} -xref: PMID:12598407 {source="Europe PMC"} -xref: PMID:14529453 {source="Europe PMC"} -xref: PMID:14703794 {source="Europe PMC"} -xref: PMID:14726604 {source="Europe PMC"} -xref: PMID:15586010 {source="Europe PMC"} -xref: PMID:15807660 {source="Europe PMC"} -xref: PMID:15952898 {source="Europe PMC"} -xref: PMID:1671684 {source="Europe PMC"} -xref: PMID:16771675 {source="Europe PMC"} -xref: PMID:16814528 {source="Europe PMC"} -xref: PMID:17052238 {source="Europe PMC"} -xref: PMID:17303648 {source="Europe PMC"} -xref: PMID:17531522 {source="Europe PMC"} -xref: PMID:18519744 {source="Europe PMC"} -xref: PMID:18827931 {source="Europe PMC"} -xref: PMID:19273321 {source="Europe PMC"} -xref: PMID:19482633 {source="Europe PMC"} -xref: PMID:19628033 {source="Europe PMC"} -xref: PMID:19857607 {source="Europe PMC"} -xref: PMID:19914407 {source="Europe PMC"} -xref: PMID:20868230 {source="Europe PMC"} -xref: PMID:21297912 {source="Europe PMC"} -xref: PMID:21434856 {source="Europe PMC"} -xref: PMID:21473702 {source="Europe PMC"} -xref: PMID:2160451 {source="Europe PMC"} -xref: PMID:217531 {source="Europe PMC"} -xref: PMID:22198225 {source="Europe PMC"} -xref: PMID:22247596 {source="Europe PMC"} -xref: PMID:22521482 {source="Europe PMC"} -xref: PMID:22729857 {source="Europe PMC"} -xref: PMID:22759590 {source="Europe PMC"} -xref: PMID:23542447 {source="Europe PMC"} -xref: PMID:23660153 {source="Europe PMC"} -xref: PMID:23668959 {source="Europe PMC"} -xref: PMID:24567847 {source="Europe PMC"} -xref: PMID:24862271 {source="Europe PMC"} -xref: PMID:2552230 {source="Europe PMC"} -xref: PMID:26047895 {source="Europe PMC"} -xref: PMID:26475962 {source="Europe PMC"} -xref: PMID:26875845 {source="Europe PMC"} -xref: PMID:27066025 {source="Europe PMC"} -xref: PMID:27066179 {source="Europe PMC"} -xref: PMID:27085844 {source="Europe PMC"} -xref: PMID:27357008 {source="Europe PMC"} -xref: PMID:27590268 {source="Europe PMC"} -xref: PMID:27965593 {source="Europe PMC"} -xref: PMID:28341974 {source="Europe PMC"} -xref: PMID:28599858 {source="Europe PMC"} -xref: PMID:28825637 {source="Europe PMC"} -xref: PMID:28842347 {source="Europe PMC"} -xref: PMID:28842493 {source="Europe PMC"} -xref: PMID:29259135 {source="Europe PMC"} -xref: PMID:29385710 {source="Europe PMC"} -xref: PMID:29669742 {source="Europe PMC"} -xref: PMID:29896077 {source="Europe PMC"} -xref: PMID:30307099 {source="Europe PMC"} -xref: PMID:30500433 {source="Europe PMC"} -xref: PMID:30573187 {source="Europe PMC"} -xref: PMID:30886134 {source="Europe PMC"} -xref: PMID:31254369 {source="Europe PMC"} -xref: PMID:31484901 {source="Europe PMC"} -xref: PMID:32144830 {source="Europe PMC"} -xref: PMID:32220789 {source="Europe PMC"} -xref: PMID:32478084 {source="Europe PMC"} -xref: PMID:32667121 {source="Europe PMC"} -xref: PMID:32760286 {source="Europe PMC"} -xref: PMID:32927603 {source="Europe PMC"} -xref: PMID:33248264 {source="Europe PMC"} -xref: PMID:33716500 {source="Europe PMC"} -xref: PMID:33805942 {source="Europe PMC"} -xref: PMID:34635271 {source="Europe PMC"} -xref: PMID:7998676 {source="Europe PMC"} -xref: PMID:8577306 {source="Europe PMC"} -xref: PMID:8720916 {source="Europe PMC"} -xref: PMID:8959373 {source="Europe PMC"} -xref: PMID:9337481 {source="Europe PMC"} -xref: Wikipedia:Superoxide -is_a: CHEBI:33263 ! diatomic oxygen -is_a: CHEBI:36876 ! inorganic radical anion -is_a: CHEBI:61073 ! oxygen radical -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "O2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/HO2/c1-2/h1H/p-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OUUQCZGPVNCOIJ-UHFFFAOYSA-M" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "31.999" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "31.98983" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O][O-]" xsd:string - -[Term] -id: CHEBI:20664 -name: 5beta-cholane -namespace: chebi_ontology -subset: 3_STAR -synonym: "5beta-cholane" EXACT IUPAC_NAME [IUPAC] -xref: Beilstein:2048472 {source="Beilstein"} -is_a: CHEBI:35519 ! cholane -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C24H42" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C24H42/c1-5-8-17(2)20-12-13-21-19-11-10-18-9-6-7-15-23(18,3)22(19)14-16-24(20,21)4/h17-22H,5-16H2,1-4H3/t17-,18+,19+,20-,21+,22+,23+,24-/m1/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QSHQKIURKJITMZ-OBUPQJQESA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "330.59028" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "330.32865" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]12CCCC[C@]1(C)[C@@]1([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC2)[C@H](C)CCC" xsd:string - -[Term] -id: CHEBI:22160 -name: acetamides -namespace: chebi_ontology -def: "Compounds with the general formula RNHC(=O)CH3." [] -subset: 3_STAR -is_a: CHEBI:37622 ! carboxamide - -[Term] -id: CHEBI:22221 -name: acyl group -namespace: chebi_ontology -def: "An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids." [] -subset: 3_STAR -synonym: "acyl group" EXACT [IUPAC] -synonym: "acyl groups" RELATED [ChEBI] -synonym: "alkanoyl" EXACT IUPAC_NAME [IUPAC] -synonym: "alkanoyl group" RELATED [ChEBI] -synonym: "groupe acyle" RELATED [IUPAC] -is_a: CHEBI:33247 ! organic group - -[Term] -id: CHEBI:22313 -name: alkaline earth metal atom -namespace: chebi_ontology -subset: 3_STAR -synonym: "alkaline earth metal" RELATED [ChEBI] -synonym: "alkaline earth metals" EXACT IUPAC_NAME [IUPAC] -synonym: "alkaline-earth metal" RELATED [ChEBI] -synonym: "alkaline-earth metals" RELATED [ChEBI] -synonym: "Erdalkalimetall" RELATED [ChEBI] -synonym: "Erdalkalimetalle" RELATED [ChEBI] -synonym: "metal alcalino-terreux" RELATED [ChEBI] -synonym: "metal alcalinoterreo" RELATED [ChEBI] -synonym: "metales alcalinoterreos" RELATED [ChEBI] -synonym: "metaux alcalino-terreux" RELATED [ChEBI] -is_a: CHEBI:33318 ! main group element atom -is_a: CHEBI:33521 ! metal atom -is_a: CHEBI:33559 ! s-block element atom - -[Term] -id: CHEBI:22314 -name: alkali metal atom -namespace: chebi_ontology -subset: 3_STAR -synonym: "alkali metal" RELATED [ChEBI] -synonym: "alkali metals" EXACT IUPAC_NAME [IUPAC] -synonym: "Alkalimetall" RELATED [ChEBI] -synonym: "Alkalimetalle" RELATED [ChEBI] -synonym: "metal alcalin" RELATED [ChEBI] -synonym: "metal alcalino" RELATED [ChEBI] -synonym: "metales alcalinos" RELATED [ChEBI] -synonym: "metaux alcalins" RELATED [ChEBI] -is_a: CHEBI:33318 ! main group element atom -is_a: CHEBI:33521 ! metal atom -is_a: CHEBI:33559 ! s-block element atom - -[Term] -id: CHEBI:22315 -name: alkaloid -namespace: chebi_ontology -def: "Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids." [] -subset: 3_STAR -synonym: "alcaloide" RELATED [ChEBI] -synonym: "alcaloides" RELATED [ChEBI] -synonym: "Alkaloid" EXACT [ChEBI] -synonym: "Alkaloide" RELATED [ChEBI] -synonym: "alkaloids" EXACT IUPAC_NAME [IUPAC] -xref: Wikipedia:Alkaloid -is_a: CHEBI:35352 ! organonitrogen compound -relationship: RO:0000087 CHEBI:25212 ! has role metabolite - -[Term] -id: CHEBI:22506 -name: aminoglycan -namespace: chebi_ontology -subset: 3_STAR -synonym: "aminoglycans" RELATED [ChEBI] -is_a: CHEBI:35352 ! organonitrogen compound -is_a: CHEBI:65212 ! polysaccharide derivative - -[Term] -id: CHEBI:22563 -name: anion -namespace: chebi_ontology -def: "A monoatomic or polyatomic species having one or more elementary charges of the electron." [] -subset: 3_STAR -synonym: "Anion" EXACT [ChEBI] -synonym: "anion" EXACT IUPAC_NAME [IUPAC] -synonym: "anion" EXACT [ChEBI] -synonym: "Anionen" RELATED [ChEBI] -synonym: "aniones" RELATED [ChEBI] -synonym: "anions" RELATED [IUPAC] -is_a: CHEBI:24870 ! ion - -[Term] -id: CHEBI:22586 -name: antioxidant -namespace: chebi_ontology -def: "A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides." [] -subset: 3_STAR -synonym: "antioxidants" RELATED [ChEBI] -synonym: "antioxydant" RELATED [ChEBI] -synonym: "antoxidant" RELATED [ChEBI] -is_a: CHEBI:51086 ! chemical role - -[Term] -id: CHEBI:22695 -name: base -namespace: chebi_ontology -def: "A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base)." [] -subset: 3_STAR -synonym: "Base" EXACT [ChEBI] -synonym: "base" EXACT [ChEBI] -synonym: "base" EXACT IUPAC_NAME [IUPAC] -synonym: "Base1" RELATED [KEGG_COMPOUND] -synonym: "Base2" RELATED [KEGG_COMPOUND] -synonym: "Basen" RELATED [ChEBI] -synonym: "bases" RELATED [ChEBI] -synonym: "Nucleobase" RELATED [KEGG_COMPOUND] -xref: KEGG:C00701 -is_a: CHEBI:51086 ! chemical role - -[Term] -id: CHEBI:22728 -name: benzopyrrole -namespace: chebi_ontology -subset: 3_STAR -synonym: "benzopyrroles" RELATED [ChEBI:] -synonym: "benzopyrroles" RELATED [ChEBI] -is_a: CHEBI:27171 ! organic heterobicyclic compound -is_a: CHEBI:38101 ! organonitrogen heterocyclic compound -is_a: CHEBI:38180 ! polycyclic heteroarene - -[Term] -id: CHEBI:22868 -name: bile salt -namespace: chebi_ontology -def: "A sodium salt of the conjugate of any bile acid with either glycine or taurine." [] -subset: 3_STAR -synonym: "Bile acid" RELATED [KEGG_COMPOUND] -synonym: "bile salts" RELATED [ChEBI] -xref: KEGG:C01558 -is_a: CHEBI:36078 ! cholanoid -is_a: CHEBI:38700 ! organic sodium salt - -[Term] -id: CHEBI:22984 -name: calcium atom -namespace: chebi_ontology -subset: 3_STAR -synonym: "20Ca" RELATED [IUPAC] -synonym: "Ca" RELATED [IUPAC] -synonym: "Ca" RELATED [UniProt] -synonym: "calcio" RELATED [ChEBI] -synonym: "Calcium" RELATED [KEGG_COMPOUND] -synonym: "calcium" EXACT IUPAC_NAME [IUPAC] -synonym: "calcium" RELATED [ChEBI] -synonym: "Kalzium" RELATED [ChEBI] -xref: CAS:7440-70-2 {source="ChemIDplus"} -xref: DrugBank:DB01373 -xref: KEGG:C00076 -xref: WebElements:Ca -is_a: CHEBI:22313 ! alkaline earth metal atom -relationship: RO:0000087 CHEBI:33937 ! has role macronutrient -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "Ca" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Ca" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OYPRJOBELJOOCE-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "40.07800" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "39.96259" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Ca]" xsd:string - -[Term] -id: CHEBI:22985 -name: calcium molecular entity -namespace: chebi_ontology -subset: 3_STAR -synonym: "calcium compounds" RELATED [ChEBI] -synonym: "calcium molecular entities" RELATED [ChEBI] -synonym: "calcium molecular entity" EXACT [ChEBI] -is_a: CHEBI:33299 ! alkaline earth molecular entity -relationship: has_part CHEBI:22984 ! calcium atom - -[Term] -id: CHEBI:23004 -name: carbamoyl group -namespace: chebi_ontology -def: "The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid." [] -subset: 3_STAR -synonym: "-C(O)NH2" RELATED [ChEBI] -synonym: "-CONH2" RELATED [IUPAC] -synonym: "aminocarbonyl" RELATED [IUPAC] -synonym: "carbamoyl" EXACT IUPAC_NAME [IUPAC] -synonym: "carbamyl" RELATED [ChEBI] -synonym: "carbamyl group" RELATED [ChEBI] -synonym: "carboxamide" RELATED [IUPAC] -xref: PMID:24168430 {source="Europe PMC"} -is_a: CHEBI:27207 ! univalent carboacyl group -relationship: is_substituent_group_from CHEBI:28616 ! carbamic acid -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2NO" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "44.03272" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.01364" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "*C(N)=O" xsd:string - -[Term] -id: CHEBI:23019 -name: carbonyl group -namespace: chebi_ontology -subset: 3_STAR -synonym: ">C=O" RELATED [IUPAC] -synonym: "carbonyl" EXACT IUPAC_NAME [IUPAC] -synonym: "carbonyl group" EXACT [ChEBI] -synonym: "carbonyl group" EXACT [UniProt] -is_a: CHEBI:51422 ! organodiyl group -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CO" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "28.01010" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "27.99491" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=C(*)*" xsd:string - -[Term] -id: CHEBI:23357 -name: cofactor -namespace: chebi_ontology -def: "An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group)." [] -subset: 3_STAR -synonym: "cofactor" EXACT [IUPAC] -synonym: "cofactors" EXACT IUPAC_NAME [IUPAC] -xref: Wikipedia:Cofactor_(biochemistry) -is_a: CHEBI:52206 ! biochemical role - -[Term] -id: CHEBI:23367 -name: molecular entity -namespace: chebi_ontology -def: "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." [ANON:ANON] -subset: 3_STAR -synonym: "entidad molecular" RELATED [IUPAC:] -synonym: "entidad molecular" RELATED [IUPAC] -synonym: "entidades moleculares" RELATED [IUPAC:] -synonym: "entidades moleculares" RELATED [IUPAC] -synonym: "entite moleculaire" RELATED [IUPAC] -synonym: "entite moleculaire" RELATED [IUPAC:] -synonym: "molecular entities" RELATED [IUPAC:] -synonym: "molecular entities" RELATED [IUPAC] -synonym: "molecular entity" EXACT IUPAC_NAME [IUPAC:] -synonym: "molecular entity" EXACT IUPAC_NAME [IUPAC] -synonym: "molekulare Entitaet" RELATED [ChEBI] -synonym: "molekulare Entitaet" RELATED [ChEBI:] -is_a: CHEBI:24431 ! chemical entity - -[Term] -id: CHEBI:23449 -name: cyclic peptide -namespace: chebi_ontology -subset: 3_STAR -synonym: "cyclic peptides" RELATED [ChEBI] -synonym: "Cyclopeptid" RELATED [ChEBI] -synonym: "peptide cyclique" RELATED [IUPAC] -synonym: "peptido ciclico" RELATED [IUPAC] -synonym: "Zyklopeptid" RELATED [ChEBI] -is_a: CHEBI:16670 ! peptide - -[Term] -id: CHEBI:23677 -name: diazole -namespace: chebi_ontology -def: "An azole that is either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring." [] -def: "Either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring." [ANON:ANON] -subset: 3_STAR -synonym: "diazoles" RELATED [ChEBI] -synonym: "diazoles" RELATED [ChEBI:] -is_a: CHEBI:68452 ! azole - -[Term] -id: CHEBI:23888 -name: drug -namespace: chebi_ontology -def: "Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances." [] -subset: 3_STAR -synonym: "drugs" RELATED [ChEBI] -synonym: "medicine" RELATED [ChEBI] -is_a: CHEBI:52217 ! pharmaceutical - -[Term] -id: CHEBI:23897 -name: ecdysteroid -namespace: chebi_ontology -alt_id: CHEBI:23896 -def: "A class of steroids that include insect moulting and sex hormones." [] -subset: 3_STAR -synonym: "ecdysteroid hormones" RELATED [ChEBI] -synonym: "ecdysteroids" RELATED [ChEBI] -xref: Wikipedia:Ecdysteroid -is_a: CHEBI:35341 ! steroid -relationship: RO:0000087 CHEBI:24621 ! has role hormone - -[Term] -id: CHEBI:23906 -name: monoatomic cation -namespace: chebi_ontology -subset: 3_STAR -synonym: "monoatomic cations" RELATED [ChEBI] -is_a: CHEBI:24867 ! monoatomic ion -is_a: CHEBI:36916 ! cation - -[Term] -id: CHEBI:23924 -name: enzyme inhibitor -namespace: chebi_ontology -def: "A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction." [] -subset: 3_STAR -synonym: "enzyme inhibitor" EXACT IUPAC_NAME [IUPAC] -synonym: "enzyme inhibitors" RELATED [ChEBI] -synonym: "inhibidor enzimatico" RELATED [ChEBI] -synonym: "inhibidores enzimaticos" RELATED [ChEBI] -synonym: "inhibiteur enzymatique" RELATED [ChEBI] -synonym: "inhibiteurs enzymatiques" RELATED [ChEBI] -is_a: CHEBI:35222 ! inhibitor -is_a: CHEBI:52206 ! biochemical role - -[Term] -id: CHEBI:23965 -name: estradiol -namespace: chebi_ontology -alt_id: CHEBI:42364 -def: "A 3-hydroxy steroid that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17." [] -subset: 3_STAR -synonym: "estra-1,3,5(10)-triene-3,17-diol" EXACT IUPAC_NAME [IUPAC] -synonym: "oestradiol" RELATED [ChEBI] -xref: PMID:10696569 {source="Europe PMC"} -xref: PMID:24084694 {source="Europe PMC"} -xref: Wikipedia:Estradiol -is_a: CHEBI:177917 ! phenolic steroid -is_a: CHEBI:36838 ! 17-hydroxy steroid -relationship: has_parent_hydride CHEBI:23966 ! estrane -relationship: RO:0000087 CHEBI:50114 ! has role estrogen -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C18H24O2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17?,18+/m1/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "VOXZDWNPVJITMN-WKUFJEKOSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "272.38196" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "272.17763" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@]12CC[C@]3(C)C(O)CC[C@@]3([H])[C@]1([H])CCc1cc(O)ccc21" xsd:string - -[Term] -id: CHEBI:23966 -name: estrane -namespace: chebi_ontology -subset: 3_STAR -synonym: "estrane" EXACT IUPAC_NAME [IUPAC] -synonym: "Oestran" RELATED [ChEBI] -synonym: "oestrane" RELATED [JCBN] -xref: Beilstein:3125721 {source="Beilstein"} -xref: LIPID_MAPS_instance:LMST02010000 {source="LIPID MAPS"} -is_a: CHEBI:35508 ! steroid fundamental parent -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C18H30" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C18H30/c1-18-11-4-7-17(18)16-9-8-13-5-2-3-6-14(13)15(16)10-12-18/h13-17H,2-12H2,1H3/t13?,14-,15+,16+,17-,18-/m0/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "GRXPVLPQNMUNNX-MHJRRCNVSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "246.43080" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "246.23475" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@]12CCCCC1CC[C@]1([H])[C@]2([H])CC[C@]2(C)CCC[C@@]12[H]" xsd:string - -[Term] -id: CHEBI:24261 -name: glucocorticoid -namespace: chebi_ontology -def: "Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood." [] -subset: 3_STAR -synonym: "glucocorticoids" RELATED [ChEBI] -is_a: CHEBI:36699 ! corticosteroid hormone - -[Term] -id: CHEBI:24318 -name: glutamine family amino acid -namespace: chebi_ontology -def: "An L-alpha-amino acid which is L-glutamic acid or any of the essential amino acids biosynthesised from it (glutamine, proline and arginine). A closed class." [] -subset: 3_STAR -synonym: "glutamine family amino acids" RELATED [ChEBI] -xref: PMID:20716061 {source="Europe PMC"} -is_a: CHEBI:15705 ! L-alpha-amino acid -is_a: CHEBI:83813 ! proteinogenic amino acid - -[Term] -id: CHEBI:24384 -name: glycogens -namespace: chebi_ontology -subset: 3_STAR -is_a: CHEBI:37163 ! glucan - -[Term] -id: CHEBI:24402 -name: glycosphingolipid -namespace: chebi_ontology -alt_id: CHEBI:5498 -def: "A glycosphingolipid is a glycolipid that is a carbohydrate-containing derivative of a sphingoid or ceramide. It is understood that the carbohydrate residue is attached by a glycosidic linkage to O-1 of the sphingoid." [] -subset: 3_STAR -synonym: "glycosphingolipids" RELATED [ChEBI] -xref: PMID:18845618 {source="Europe PMC"} -xref: PMID:19303901 {source="Europe PMC"} -xref: PMID:26954668 {source="Europe PMC"} -xref: PMID:26976737 {source="Europe PMC"} -xref: PMID:27253729 {source="Europe PMC"} -xref: PMID:27325407 {source="Europe PMC"} -xref: Wikipedia:Glycosphingolipid -is_a: CHEBI:26739 ! sphingolipid -is_a: CHEBI:33563 ! glycolipid [Term] id: CHEBI:24431 -name: chemical entity namespace: chebi_ontology def: "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." [ANON:ANON] -subset: 3_STAR -synonym: "chemical entity" EXACT [UniProt] is_a: BFO:0000040 ! material entity -[Term] -id: CHEBI:24432 -name: biological role -namespace: chebi_ontology -def: "A role played by the molecular entity or part thereof within a biological context." [] -subset: 3_STAR -synonym: "biological function" RELATED [ChEBI] -is_a: BFO:0000023 ! role -is_a: CHEBI:50906 ! role - -[Term] -id: CHEBI:24433 -name: group -namespace: chebi_ontology -def: "A defined linked collection of atoms or a single atom within a molecular entity." [] -subset: 3_STAR -synonym: "group" EXACT IUPAC_NAME [IUPAC] -synonym: "groupe" RELATED [IUPAC] -synonym: "grupo" RELATED [IUPAC] -synonym: "grupos" RELATED [IUPAC] -synonym: "Gruppe" RELATED [ChEBI] -synonym: "Rest" RELATED [ChEBI] -is_a: CHEBI:24431 ! chemical entity -relationship: has_part CHEBI:33250 ! atom - -[Term] -id: CHEBI:24505 -name: heparins -namespace: chebi_ontology -subset: 3_STAR -is_a: CHEBI:35722 ! sulfated glycosaminoglycan -is_a: CHEBI:37395 ! mucopolysaccharide - -[Term] -id: CHEBI:24532 -name: organic heterocyclic compound -namespace: chebi_ontology -def: "A cyclic compound having as ring members atoms of carbon and at least of one other element." [ANON:ANON] -subset: 3_STAR -synonym: "organic heterocycle" RELATED [ChEBI:] -synonym: "organic heterocycle" RELATED [ChEBI] -synonym: "organic heterocyclic compounds" RELATED [ChEBI] -synonym: "organic heterocyclic compounds" RELATED [ChEBI:] -is_a: CHEBI:33285 ! heteroorganic entity -is_a: CHEBI:33832 ! organic cyclic compound -is_a: CHEBI:5686 ! heterocyclic compound - -[Term] -id: CHEBI:24533 -name: heterodetic cyclic peptide -namespace: chebi_ontology -def: "A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond." [] -subset: 3_STAR -synonym: "heterodetic cyclic peptide" EXACT IUPAC_NAME [IUPAC] -synonym: "heterodetic cyclic peptides" RELATED [ChEBI] -synonym: "peptide cyclique heterodetique" RELATED [IUPAC] -synonym: "peptido ciclico heterodetico" RELATED [IUPAC] -is_a: CHEBI:23449 ! cyclic peptide - -[Term] -id: CHEBI:24621 -name: hormone -namespace: chebi_ontology -def: "Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds." [] -subset: 3_STAR -synonym: "endocrine" RELATED [ChEBI] -synonym: "hormones" RELATED [ChEBI] -is_a: CHEBI:33280 ! molecular messenger -is_a: CHEBI:48705 ! agonist - -[Term] -id: CHEBI:24632 -name: hydrocarbon -namespace: chebi_ontology -def: "A compound consisting of carbon and hydrogen only." [] -subset: 3_STAR -synonym: "hidrocarburo" RELATED [IUPAC] -synonym: "hidrocarburos" RELATED [IUPAC] -synonym: "hydrocarbon" EXACT IUPAC_NAME [IUPAC] -synonym: "hydrocarbons" EXACT IUPAC_NAME [IUPAC] -synonym: "hydrocarbure" RELATED [IUPAC] -synonym: "Kohlenwasserstoff" RELATED [ChEBI] -synonym: "Kohlenwasserstoffe" RELATED [ChEBI] -is_a: CHEBI:33245 ! organic fundamental parent - -[Term] -id: CHEBI:24651 -name: hydroxides -namespace: chebi_ontology -def: "Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-))." [ANON:ANON] -subset: 3_STAR -is_a: CHEBI:25806 ! oxygen molecular entity -is_a: CHEBI:33608 ! hydrogen molecular entity -is_a: CHEBI:37577 ! heteroatomic molecular entity -relationship: has_part CHEBI:43176 ! hydroxy group - -[Term] -id: CHEBI:24663 -name: hydroxy-5beta-cholanic acid -namespace: chebi_ontology -def: "Any member of the class of 5beta-cholanic acids carrying at least one hydroxy group at unspecified position." [] -subset: 3_STAR -synonym: "hydroxy-5beta-cholanic acids" RELATED [ChEBI] -is_a: CHEBI:33822 ! organic hydroxy compound -is_a: CHEBI:36248 ! 5beta-cholanic acids -relationship: has_functional_parent CHEBI:36238 ! 5beta-cholanic acid - [Term] id: CHEBI:24780 -name: imidazoles namespace: chebi_ontology def: "A five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton." [ANON:ANON] -subset: 3_STAR -is_a: CHEBI:23677 ! diazole [Term] id: CHEBI:24828 -name: indoles namespace: chebi_ontology def: "Any compound containing an indole skeleton." [ANON:ANON] -subset: 3_STAR -is_a: CHEBI:22728 ! benzopyrrole - -[Term] -id: CHEBI:24833 -name: oxoacid -namespace: chebi_ontology -def: "A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." [ANON:ANON] -subset: 3_STAR -synonym: "oxacids" RELATED [ChEBI] -synonym: "oxacids" RELATED [ChEBI:] -synonym: "oxiacids" RELATED [ChEBI:] -synonym: "oxiacids" RELATED [ChEBI] -synonym: "oxo acid" RELATED [ChEBI:] -synonym: "oxo acid" RELATED [ChEBI] -synonym: "oxoacid" EXACT IUPAC_NAME [IUPAC] -synonym: "oxoacid" EXACT IUPAC_NAME [IUPAC:] -synonym: "oxoacids" EXACT IUPAC_NAME [IUPAC:] -synonym: "oxoacids" EXACT IUPAC_NAME [IUPAC] -synonym: "oxy-acids" RELATED [ChEBI:] -synonym: "oxy-acids" RELATED [ChEBI] -synonym: "oxyacids" RELATED [ChEBI] -synonym: "oxyacids" RELATED [ChEBI:] -is_a: CHEBI:24651 ! hydroxides -relationship: RO:0000087 CHEBI:39141 ! has role Bronsted acid - -[Term] -id: CHEBI:24834 -name: inorganic anion -namespace: chebi_ontology -subset: 3_STAR -synonym: "inorganic anions" RELATED [ChEBI] -is_a: CHEBI:22563 ! anion -is_a: CHEBI:36914 ! inorganic ion - -[Term] -id: CHEBI:24835 -name: inorganic molecular entity -namespace: chebi_ontology -def: "A molecular entity that contains no carbon." [] -subset: 3_STAR -synonym: "anorganische Verbindungen" RELATED [ChEBI] -synonym: "inorganic compounds" RELATED [ChEBI] -synonym: "inorganic entity" RELATED [ChEBI] -synonym: "inorganic molecular entities" RELATED [ChEBI] -synonym: "inorganics" RELATED [ChEBI] -is_a: CHEBI:23367 ! molecular entity - -[Term] -id: CHEBI:24836 -name: inorganic oxide -namespace: chebi_ontology -subset: 3_STAR -synonym: "inorganic oxides" RELATED [ChEBI] -is_a: CHEBI:24835 ! inorganic molecular entity -is_a: CHEBI:25741 ! oxide - -[Term] -id: CHEBI:24866 -name: salt -namespace: chebi_ontology -def: "A salt is an assembly of cations and anions." [] -subset: 3_STAR -synonym: "ionic compound" RELATED [ChEBI] -synonym: "ionic compounds" RELATED [ChEBI] -synonym: "sal" RELATED [ChEBI] -synonym: "sales" RELATED [ChEBI] -synonym: "salt" EXACT IUPAC_NAME [IUPAC] -synonym: "salts" RELATED [ChEBI] -synonym: "Salz" RELATED [ChEBI] -synonym: "Salze" RELATED [ChEBI] -synonym: "sel" RELATED [ChEBI] -synonym: "sels" RELATED [ChEBI] -is_a: CHEBI:37577 ! heteroatomic molecular entity -relationship: has_part CHEBI:22563 ! anion -relationship: has_part CHEBI:36916 ! cation - -[Term] -id: CHEBI:24867 -name: monoatomic ion -namespace: chebi_ontology -subset: 3_STAR -synonym: "monoatomic ions" RELATED [ChEBI] -is_a: CHEBI:24870 ! ion -is_a: CHEBI:33238 ! monoatomic entity - -[Term] -id: CHEBI:24868 -name: organic salt -namespace: chebi_ontology -subset: 3_STAR -synonym: "organic salts" RELATED [ChEBI] -synonym: "organisches Salz" RELATED [ChEBI] -is_a: CHEBI:24866 ! salt - -[Term] -id: CHEBI:24870 -name: ion -namespace: chebi_ontology -def: "A molecular entity having a net electric charge." [ANON:ANON] -subset: 3_STAR -synonym: "Ion" EXACT [ChEBI] -synonym: "Ion" EXACT [ChEBI:] -synonym: "ion" EXACT IUPAC_NAME [IUPAC:] -synonym: "ion" EXACT IUPAC_NAME [IUPAC] -synonym: "ion" EXACT [ChEBI] -synonym: "ion" EXACT [ChEBI:] -synonym: "Ionen" RELATED [ChEBI:] -synonym: "Ionen" RELATED [ChEBI] -synonym: "iones" RELATED [ChEBI:] -synonym: "iones" RELATED [ChEBI] -synonym: "ions" RELATED [ChEBI:] -synonym: "ions" RELATED [ChEBI] -is_a: CHEBI:23367 ! molecular entity - -[Term] -id: CHEBI:24873 -name: iron molecular entity -namespace: chebi_ontology -subset: 3_STAR -synonym: "iron compounds" RELATED [ChEBI] -synonym: "iron molecular entities" RELATED [ChEBI] -synonym: "iron molecular entity" EXACT [ChEBI] -is_a: CHEBI:33744 ! iron group molecular entity -relationship: has_part CHEBI:18248 ! iron atom - -[Term] -id: CHEBI:24875 -name: iron cation -namespace: chebi_ontology -subset: 3_STAR -synonym: "Fe cation" RELATED [UniProt] -synonym: "iron cation" EXACT IUPAC_NAME [IUPAC] -synonym: "iron cations" RELATED [ChEBI] -is_a: CHEBI:33515 ! transition element cation -is_a: CHEBI:82663 ! elemental iron -relationship: RO:0000087 CHEBI:23357 ! has role cofactor -property_value: http://purl.obolibrary.org/obo/chebi/formula "Fe" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "55.845" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "55.93494" xsd:string - -[Term] -id: CHEBI:24913 -name: isoprenoid -namespace: chebi_ontology -def: "Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives." [] -subset: 3_STAR -synonym: "isoprenoid" EXACT [ChEBI] -synonym: "isoprenoids" EXACT IUPAC_NAME [IUPAC] -synonym: "isoprenoids" RELATED [ChEBI] -xref: LIPID_MAPS_class:LMPR01 {source="LIPID MAPS"} -xref: PMID:12769708 {source="Europe PMC"} -xref: PMID:19219049 {source="Europe PMC"} -is_a: CHEBI:18059 ! lipid - -[Term] -id: CHEBI:24943 -name: juvenile hormone -namespace: chebi_ontology -def: "A family of farnesane sesquiterpenoids that regulate many aspects of insect physiology." [] -subset: 3_STAR -xref: Wikipedia:Juvenile_hormone -is_a: CHEBI:36757 ! farnesane sesquiterpenoid -relationship: RO:0000087 CHEBI:24621 ! has role hormone -relationship: RO:0000087 CHEBI:75767 ! has role animal metabolite - -[Term] -id: CHEBI:25046 -name: linear tetrapyrrole -namespace: chebi_ontology -subset: 1_STAR -is_a: CHEBI:26932 ! tetrapyrrole - -[Term] -id: CHEBI:25212 -name: metabolite -namespace: chebi_ontology -alt_id: CHEBI:26619 -alt_id: CHEBI:35220 -def: "Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites." [] -subset: 3_STAR -synonym: "metabolite" EXACT IUPAC_NAME [IUPAC] -synonym: "metabolites" RELATED [ChEBI] -synonym: "primary metabolites" RELATED [ChEBI] -synonym: "secondary metabolites" RELATED [ChEBI] -is_a: CHEBI:52206 ! biochemical role - -[Term] -id: CHEBI:25213 -name: metal cation -namespace: chebi_ontology -subset: 3_STAR -synonym: "a metal cation" RELATED [UniProt] -synonym: "metal cations" RELATED [ChEBI] -is_a: CHEBI:23906 ! monoatomic cation -is_a: CHEBI:36915 ! inorganic cation - -[Term] -id: CHEBI:25354 -name: mineralocorticoid -namespace: chebi_ontology -def: "Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism." [] -subset: 3_STAR -synonym: "mineralocorticoids" RELATED [ChEBI] -is_a: CHEBI:36699 ! corticosteroid hormone - -[Term] -id: CHEBI:25362 -name: elemental molecule -namespace: chebi_ontology -def: "A molecule all atoms of which have the same atomic number." [] -subset: 3_STAR -synonym: "homoatomic molecule" RELATED [ChEBI] -synonym: "homoatomic molecules" RELATED [ChEBI] -is_a: CHEBI:25367 ! molecule -is_a: CHEBI:33259 ! elemental molecular entity - -[Term] -id: CHEBI:25367 -name: molecule -namespace: chebi_ontology -def: "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom." [] -subset: 3_STAR -synonym: "molecula" RELATED [IUPAC] -synonym: "molecule" EXACT [IUPAC] -synonym: "molecules" RELATED [IUPAC] -synonym: "Molekuel" RELATED [ChEBI] -synonym: "neutral molecular compounds" RELATED [IUPAC] -is_a: CHEBI:36357 ! polyatomic entity - -[Term] -id: CHEBI:25375 -name: monoamine molecular messenger -namespace: chebi_ontology -def: "A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." [] -subset: 3_STAR -synonym: "monamines" RELATED [ChEBI] -synonym: "monoamines" RELATED [ChEBI] -is_a: CHEBI:63534 ! monoamine -relationship: RO:0000087 CHEBI:33280 ! has role molecular messenger - -[Term] -id: CHEBI:25384 -name: monocarboxylic acid -namespace: chebi_ontology -def: "An oxoacid containing a single carboxy group." [ANON:ANON] -subset: 3_STAR -synonym: "monocarboxylic acid" EXACT [UniProt:] -synonym: "monocarboxylic acids" RELATED [ChEBI] -synonym: "monocarboxylic acids" RELATED [ChEBI:] -is_a: CHEBI:33575 ! carboxylic acid -relationship: is_conjugate_acid_of CHEBI:35757 ! monocarboxylic acid anion - -[Term] -id: CHEBI:25414 -name: monoatomic monocation -namespace: chebi_ontology -subset: 3_STAR -synonym: "monoatomic monocations" RELATED [ChEBI] -synonym: "monovalent inorganic cations" RELATED [ChEBI] -is_a: CHEBI:23906 ! monoatomic cation -property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "0.00000" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*+]" xsd:string - -[Term] -id: CHEBI:25512 -name: neurotransmitter -namespace: chebi_ontology -def: "An endogenous compound that is used to transmit information across the synapse between a neuron and another cell." [] -subset: 3_STAR -synonym: "neurotransmitters" RELATED [ChEBI] -xref: Wikipedia:Neurotransmitter -is_a: CHEBI:33280 ! molecular messenger - -[Term] -id: CHEBI:25555 -name: nitrogen atom -namespace: chebi_ontology -subset: 3_STAR -synonym: "7N" RELATED [IUPAC] -synonym: "azote" RELATED [IUPAC] -synonym: "N" RELATED [IUPAC] -synonym: "nitrogen" EXACT IUPAC_NAME [IUPAC] -synonym: "nitrogen" RELATED [ChEBI] -synonym: "nitrogeno" RELATED [ChEBI] -synonym: "Stickstoff" RELATED [ChEBI] -xref: WebElements:N -is_a: CHEBI:25585 ! nonmetal atom -is_a: CHEBI:33300 ! pnictogen -relationship: RO:0000087 CHEBI:33937 ! has role macronutrient -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "14.007" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "14.00307" xsd:string - -[Term] -id: CHEBI:25585 -name: nonmetal atom -namespace: chebi_ontology -subset: 3_STAR -synonym: "Nichtmetall" RELATED [ChEBI] -synonym: "Nichtmetalle" RELATED [ChEBI] -synonym: "no metal" RELATED [ChEBI] -synonym: "no metales" RELATED [ChEBI] -synonym: "non-metal" RELATED [ChEBI] -synonym: "non-metaux" RELATED [ChEBI] -synonym: "nonmetal" EXACT IUPAC_NAME [IUPAC] -synonym: "nonmetal" RELATED [ChEBI] -synonym: "nonmetals" RELATED [ChEBI] -is_a: CHEBI:33250 ! atom - -[Term] -id: CHEBI:25696 -name: organic anion -namespace: chebi_ontology -def: "Any organic ion with a net negative charge." [] -subset: 3_STAR -synonym: "organic anions" RELATED [ChEBI] -is_a: CHEBI:22563 ! anion -is_a: CHEBI:25699 ! organic ion - -[Term] -id: CHEBI:25697 -name: organic cation -namespace: chebi_ontology -def: "Any organic ion with a net positive charge." [] -subset: 3_STAR -synonym: "organic cations" RELATED [ChEBI] -is_a: CHEBI:25699 ! organic ion -is_a: CHEBI:36916 ! cation - -[Term] -id: CHEBI:25699 -name: organic ion -namespace: chebi_ontology -subset: 3_STAR -synonym: "organic ions" RELATED [ChEBI] -is_a: CHEBI:24870 ! ion -is_a: CHEBI:50860 ! organic molecular entity - -[Term] -id: CHEBI:25704 -name: organic sulfate -namespace: chebi_ontology -def: "Compounds of the general formula SO3HOR where R is an organyl group" [] -subset: 3_STAR -synonym: "organic sulfates" RELATED [ChEBI] -is_a: CHEBI:26820 ! sulfates -relationship: is_conjugate_acid_of CHEBI:58958 ! organosulfate oxoanion - -[Term] -id: CHEBI:25741 -name: oxide -namespace: chebi_ontology -def: "An oxide is a chemical compound of oxygen with other chemical elements." [] -subset: 3_STAR -synonym: "oxide" EXACT [ChEBI] -synonym: "oxides" RELATED [ChEBI] -is_a: CHEBI:25806 ! oxygen molecular entity -is_a: CHEBI:37577 ! heteroatomic molecular entity - -[Term] -id: CHEBI:25805 -name: oxygen atom -namespace: chebi_ontology -subset: 3_STAR -synonym: "8O" RELATED [IUPAC] -synonym: "O" RELATED [IUPAC] -synonym: "oxigeno" RELATED [ChEBI] -synonym: "oxygen" EXACT IUPAC_NAME [IUPAC] -synonym: "oxygen" RELATED [ChEBI] -synonym: "oxygene" RELATED [ChEBI] -synonym: "Sauerstoff" RELATED [ChEBI] -xref: KEGG:C00007 -xref: WebElements:O -is_a: CHEBI:25585 ! nonmetal atom -is_a: CHEBI:33303 ! chalcogen -relationship: RO:0000087 CHEBI:33937 ! has role macronutrient -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QVGXLLKOCUKJST-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "15.99940" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.99491" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O]" xsd:string [Term] id: CHEBI:25806 -name: oxygen molecular entity namespace: chebi_ontology -subset: 3_STAR -synonym: "oxygen molecular entities" RELATED [ChEBI] synonym: "oxygen molecular entities" RELATED [ChEBI:] synonym: "oxygen molecular entity" EXACT [ChEBI:] -synonym: "oxygen molecular entity" EXACT [ChEBI] -is_a: CHEBI:33304 ! chalcogen molecular entity -relationship: has_part CHEBI:25805 ! oxygen atom - -[Term] -id: CHEBI:25905 -name: peptide hormone -namespace: chebi_ontology -def: "Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine." [] -subset: 3_STAR -synonym: "peptide hormones" RELATED [ChEBI] -synonym: "polypeptide hormone" RELATED [ChEBI] -is_a: CHEBI:16670 ! peptide -relationship: RO:0000087 CHEBI:24621 ! has role hormone - -[Term] -id: CHEBI:26020 -name: phosphate -namespace: chebi_ontology -def: "Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom." [] -subset: 3_STAR -synonym: "phosphates" EXACT IUPAC_NAME [IUPAC] -synonym: "phosphates" RELATED [ChEBI] -is_a: CHEBI:26079 ! phosphoric acid derivative - -[Term] -id: CHEBI:26078 -name: phosphoric acid -namespace: chebi_ontology -def: "A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom." [] -subset: 3_STAR -synonym: "[PO(OH)3]" RELATED [IUPAC] -synonym: "acide phosphorique" RELATED [ChEBI] -synonym: "acidum phosphoricum" RELATED [ChEBI] -synonym: "H3PO4" RELATED [IUPAC] -synonym: "Orthophosphoric acid" RELATED [KEGG_COMPOUND] -synonym: "orthophosphoric acid" RELATED [NIST_Chemistry_WebBook] -synonym: "Phosphate" RELATED [KEGG_COMPOUND] -synonym: "Phosphoric acid" EXACT [KEGG_COMPOUND] -synonym: "phosphoric acid" EXACT [IUPAC] -synonym: "Phosphorsaeure" RELATED [ChEBI] -synonym: "Phosphorsaeureloesungen" RELATED [ChEBI] -synonym: "tetraoxophosphoric acid" EXACT IUPAC_NAME [IUPAC] -synonym: "trihydrogen tetraoxophosphate(3-)" EXACT IUPAC_NAME [IUPAC] -synonym: "trihydroxidooxidophosphorus" EXACT IUPAC_NAME [IUPAC] -xref: Beilstein:1921286 {source="Beilstein"} -xref: CAS:7664-38-2 {source="NIST Chemistry WebBook"} -xref: CAS:7664-38-2 {source="KEGG COMPOUND"} -xref: CAS:7664-38-2 {source="ChemIDplus"} -xref: Drug_Central:4478 {source="DrugCentral"} -xref: Gmelin:2000 {source="Gmelin"} -xref: HMDB:HMDB0002142 -xref: KEGG:C00009 -xref: KEGG:D05467 -xref: KNApSAcK:C00007408 -xref: PMID:11455380 {source="Europe PMC"} -xref: PMID:15630224 {source="Europe PMC"} -xref: PMID:17439666 {source="Europe PMC"} -xref: PMID:17518491 {source="Europe PMC"} -xref: PMID:22282755 {source="Europe PMC"} -xref: PMID:22333268 {source="Europe PMC"} -xref: PMID:22381614 {source="Europe PMC"} -xref: PMID:22401268 {source="Europe PMC"} -xref: Reaxys:1921286 {source="Reaxys"} -xref: Wikipedia:Phosphoric_Acid -is_a: CHEBI:59698 ! phosphoric acids -relationship: is_conjugate_acid_of CHEBI:39745 ! dihydrogenphosphate -relationship: RO:0000087 CHEBI:33287 ! has role fertilizer -relationship: RO:0000087 CHEBI:46787 ! has role solvent -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "H3O4P" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "97.99520" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "97.97690" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OP(=O)(O[H])O[H]" xsd:string - -[Term] -id: CHEBI:26079 -name: phosphoric acid derivative -namespace: chebi_ontology -subset: 1_STAR -is_a: CHEBI:36359 ! phosphorus oxoacid derivative -relationship: has_functional_parent CHEBI:26078 ! phosphoric acid - -[Term] -id: CHEBI:26082 -name: phosphorus molecular entity -namespace: chebi_ontology -subset: 3_STAR -synonym: "phosphorus molecular entities" RELATED [ChEBI] -is_a: CHEBI:33302 ! pnictogen molecular entity -relationship: has_part CHEBI:28659 ! phosphorus atom - -[Term] -id: CHEBI:26167 -name: polar amino acid -namespace: chebi_ontology -alt_id: CHEBI:8283 -def: "Any amino acid whose side chain is capable of forming one or more hydrogen bonds." [] -subset: 3_STAR -synonym: "polar amino acid" EXACT [ChEBI] -synonym: "polar amino acids" RELATED [ChEBI] -synonym: "polar amino-acid" RELATED [ChEBI] -synonym: "polar amino-acids" RELATED [ChEBI] -xref: MetaCyc:Polar-amino-acids -xref: PMID:12016058 {source="Europe PMC"} -is_a: CHEBI:33709 ! amino acid -relationship: is_tautomer_of CHEBI:62031 ! polar amino acid zwitterion -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "74.059" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC(C(*)N)=O" xsd:string - -[Term] -id: CHEBI:26519 -name: radical -namespace: chebi_ontology -def: "A molecular entity possessing an unpaired electron." [] -subset: 3_STAR -synonym: "free radical" RELATED [ChEBI] -synonym: "freies Radikal" RELATED [ChEBI] -synonym: "radical" EXACT IUPAC_NAME [IUPAC] -synonym: "radical libre" RELATED [ChEBI] -synonym: "radicales libres" RELATED [ChEBI] -synonym: "radicals" RELATED [IUPAC] -synonym: "Radikal" RELATED [ChEBI] -synonym: "Radikale" RELATED [ChEBI] -is_a: CHEBI:23367 ! molecular entity - -[Term] -id: CHEBI:26523 -name: reactive oxygen species -namespace: chebi_ontology -def: "Molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers." [] -subset: 3_STAR -synonym: "ROS" RELATED [ChEBI] -xref: Wikipedia:Reactive_oxygen_species -is_a: CHEBI:25806 ! oxygen molecular entity - -[Term] -id: CHEBI:26607 -name: saturated fatty acid -namespace: chebi_ontology -def: "Any fatty acid containing no carbon to carbon multiple bonds. Known to produce adverse biological effects when ingested to excess." [ANON:ANON] -subset: 3_STAR -synonym: "saturated fatty acid" EXACT [ChEBI:] -synonym: "saturated fatty acid" EXACT [ChEBI] -synonym: "saturated fatty acids" RELATED [ChEBI:] -synonym: "saturated fatty acids" RELATED [ChEBI] -synonym: "SFA" RELATED [ChEBI] -synonym: "SFA" RELATED [ChEBI:] -synonym: "SFAs" RELATED [ChEBI:] -synonym: "SFAs" RELATED [ChEBI] -xref: PMID:16492686 {source="Europe PMC"} -xref: PMID:19763019 {source="Europe PMC"} -xref: PMID:20237329 {source="Europe PMC"} -is_a: CHEBI:35366 ! fatty acid - -[Term] -id: CHEBI:26650 -name: serine family amino acid -namespace: chebi_ontology -def: "An L-alpha-amino acid which is biosynthesised from 3-phosphoglycerate (i.e. serine, glycine, cysteine and homocysteine). A closed class." [] -subset: 3_STAR -synonym: "3-phosphoglycerate family amino acid" RELATED [ChEBI] -synonym: "3-phosphoglycerate family amino acids" RELATED [ChEBI] -synonym: "serine family amino acids" RELATED [ChEBI] -xref: PMID:20709681 {source="Europe PMC"} -is_a: CHEBI:15705 ! L-alpha-amino acid -is_a: CHEBI:83813 ! proteinogenic amino acid - -[Term] -id: CHEBI:26658 -name: sesquiterpenoid -namespace: chebi_ontology -def: "Any terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups)." [] -subset: 3_STAR -synonym: "sesquiterpenoides" RELATED [ChEBI] -synonym: "sesquiterpenoids" RELATED [ChEBI] -xref: LIPID_MAPS_class:LMPR0103 {source="LIPID MAPS"} -is_a: CHEBI:26873 ! terpenoid -relationship: has_parent_hydride CHEBI:35189 ! sesquiterpene - -[Term] -id: CHEBI:26666 -name: short-chain fatty acid -namespace: chebi_ontology -def: "An aliphatic monocarboxylic acid with a chain length of less than C6." [ANON:ANON] -def: "An aliphatic monocarboxylic acid with a chain length of less than C6. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid." [] -subset: 3_STAR -synonym: "SCFA" RELATED [ChEBI] -synonym: "SCFA" RELATED [ChEBI:] -synonym: "SCFAs" RELATED [ChEBI:] -synonym: "SCFAs" RELATED [ChEBI] -synonym: "short-chain fatty acids" RELATED [ChEBI:] -synonym: "short-chain fatty acids" RELATED [ChEBI] -xref: PMID:16633129 {source="Europe PMC"} -xref: PMID:16870803 {source="Europe PMC"} -xref: PMID:18203540 {source="Europe PMC"} -xref: PMID:20148677 {source="Europe PMC"} -is_a: CHEBI:35366 ! fatty acid -relationship: is_conjugate_acid_of CHEBI:58951 ! short-chain fatty acid anion -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2OR" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "45.017" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.99765" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC([*])=O" xsd:string - -[Term] -id: CHEBI:26708 -name: sodium atom -namespace: chebi_ontology -subset: 3_STAR -synonym: "11Na" RELATED [IUPAC] -synonym: "Na" RELATED [IUPAC] -synonym: "Natrium" RELATED [ChemIDplus] -synonym: "natrium" RELATED [IUPAC] -synonym: "sodio" RELATED [ChemIDplus] -synonym: "sodium" EXACT IUPAC_NAME [IUPAC] -synonym: "sodium" RELATED [ChEBI] -xref: CAS:7440-23-5 {source="ChemIDplus"} -xref: Gmelin:16221 {source="Gmelin"} -xref: KEGG:C01330 -xref: WebElements:Na -is_a: CHEBI:22314 ! alkali metal atom -relationship: RO:0000087 CHEBI:33937 ! has role macronutrient -relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "Na" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Na" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KEAYESYHFKHZAL-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "22.98977" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "22.98977" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Na]" xsd:string - -[Term] -id: CHEBI:26712 -name: sodium molecular entity -namespace: chebi_ontology -subset: 3_STAR -synonym: "sodium compounds" RELATED [ChEBI] -synonym: "sodium molecular entities" RELATED [ChEBI] -is_a: CHEBI:33296 ! alkali metal molecular entity -relationship: has_part CHEBI:26708 ! sodium atom - -[Term] -id: CHEBI:26714 -name: sodium salt -namespace: chebi_ontology -def: "Any alkali metal salt having sodium(1+) as the cation." [] -subset: 3_STAR -synonym: "Natriumsalz" RELATED [ChEBI] -synonym: "Natriumsalze" RELATED [ChEBI] -synonym: "sodium salts" RELATED [ChEBI] -is_a: CHEBI:26712 ! sodium molecular entity -is_a: CHEBI:35479 ! alkali metal salt -relationship: has_part CHEBI:29101 ! sodium(1+) - -[Term] -id: CHEBI:26739 -name: sphingolipid -namespace: chebi_ontology -def: "Sphingolipids are a complex family of compounds that share a common structural feature, a sphingoid base backbone." [] -subset: 3_STAR -synonym: "sphingolipids" RELATED [ChEBI] -is_a: CHEBI:18059 ! lipid -is_a: CHEBI:35352 ! organonitrogen compound -is_a: CHEBI:36963 ! organooxygen compound - -[Term] -id: CHEBI:26764 -name: steroid hormone -namespace: chebi_ontology -def: "Any steroid that acts as hormone." [] -subset: 3_STAR -synonym: "hormona esteroide" RELATED [ChEBI] -synonym: "hormonas esteroideas" RELATED [ChEBI] -synonym: "hormone steroide" RELATED [ChEBI] -synonym: "hormones steroides" RELATED [ChEBI] -synonym: "steroid hormones" RELATED [ChEBI] -synonym: "Steroidhormon" RELATED [ChEBI] -synonym: "Steroidhormone" RELATED [ChEBI] -is_a: CHEBI:35341 ! steroid -relationship: RO:0000087 CHEBI:24621 ! has role hormone - -[Term] -id: CHEBI:26819 -name: sulfuric ester -namespace: chebi_ontology -def: "An ester of an alcohol and sulfuric acid." [] -subset: 3_STAR -synonym: "sulfate ester" RELATED [ChEBI] -synonym: "sulfuric acid ester" RELATED [ChEBI] -synonym: "sulfuric acid esters" RELATED [ChEBI] -is_a: CHEBI:35701 ! ester -is_a: CHEBI:37826 ! sulfuric acid derivative -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "O4SR2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "96.06300" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.95173" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]OS(=O)(=O)O[*]" xsd:string - -[Term] -id: CHEBI:26820 -name: sulfates -namespace: chebi_ontology -def: "Salts and esters of sulfuric acid" [] -subset: 3_STAR -synonym: "sulfates" EXACT [ChEBI] -synonym: "sulfuric acid derivative" RELATED [ChEBI] -synonym: "sulphates" RELATED [ChEBI] -is_a: CHEBI:37826 ! sulfuric acid derivative - -[Term] -id: CHEBI:26833 -name: sulfur atom -namespace: chebi_ontology -subset: 3_STAR -synonym: "16S" RELATED [IUPAC] -synonym: "azufre" RELATED [ChEBI] -synonym: "Elemental sulfur" RELATED [KEGG_COMPOUND] -synonym: "S" RELATED [KEGG_COMPOUND] -synonym: "S" RELATED [IUPAC] -synonym: "Schwefel" RELATED [ChEBI] -synonym: "soufre" RELATED [ChEBI] -synonym: "sulfur" EXACT IUPAC_NAME [IUPAC] -synonym: "sulfur" RELATED [ChEBI] -synonym: "sulfur" RELATED [UniProt] -synonym: "sulphur" RELATED [ChEBI] -synonym: "theion" RELATED [IUPAC] -xref: CAS:7704-34-9 {source="ChemIDplus"} -xref: CAS:7704-34-9 {source="NIST Chemistry WebBook"} -xref: KEGG:C00087 -xref: KEGG:D06527 -xref: PPDB:605 -xref: WebElements:S -is_a: CHEBI:25585 ! nonmetal atom -is_a: CHEBI:33303 ! chalcogen -relationship: RO:0000087 CHEBI:33937 ! has role macronutrient -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "S" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/S" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NINIDFKCEFEMDL-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "32.06600" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "31.97207" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[S]" xsd:string - -[Term] -id: CHEBI:26835 -name: sulfur molecular entity -namespace: chebi_ontology -subset: 3_STAR -synonym: "sulfur molecular entities" RELATED [ChEBI] -synonym: "sulfur molecular entity" EXACT [ChEBI] -is_a: CHEBI:33304 ! chalcogen molecular entity -relationship: has_part CHEBI:26833 ! sulfur atom - -[Term] -id: CHEBI:26836 -name: sulfuric acid -namespace: chebi_ontology -def: "A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom." [] -subset: 3_STAR -synonym: "[S(OH)2O2]" RELATED [MolBase] -synonym: "[SO2(OH)2]" RELATED [IUPAC] -synonym: "Acide sulfurique" RELATED [ChemIDplus] -synonym: "Acido sulfurico" RELATED [ChemIDplus] -synonym: "Acidum sulfuricum" RELATED [ChemIDplus] -synonym: "dihydrogen tetraoxosulfate" EXACT IUPAC_NAME [IUPAC] -synonym: "dihydroxidodioxidosulfur" EXACT IUPAC_NAME [IUPAC] -synonym: "H2SO4" RELATED [IUPAC] -synonym: "hydrogen tetraoxosulfate(2-)" EXACT IUPAC_NAME [IUPAC] -synonym: "hydrogen tetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC] -synonym: "Schwefelsaeureloesungen" RELATED [ChemIDplus] -synonym: "Sulfuric acid" EXACT [KEGG_COMPOUND] -synonym: "sulfuric acid" EXACT IUPAC_NAME [IUPAC] -synonym: "sulfuric acid" EXACT [ChEBI] -synonym: "sulphuric acid" RELATED [MolBase] -synonym: "tetraoxosulfuric acid" EXACT IUPAC_NAME [IUPAC] -xref: CAS:7664-93-9 {source="ChemIDplus"} -xref: CAS:7664-93-9 {source="KEGG COMPOUND"} -xref: CAS:7664-93-9 {source="NIST Chemistry WebBook"} -xref: Gmelin:2122 {source="Gmelin"} -xref: KEGG:C00059 -xref: KEGG:D05963 -xref: KNApSAcK:C00007530 -xref: MolBase:4 -xref: PMID:13568755 {source="Europe PMC"} -xref: PMID:16122922 {source="Europe PMC"} -xref: PMID:19397353 {source="Europe PMC"} -xref: PMID:22047659 {source="Europe PMC"} -xref: PMID:22136045 {source="Europe PMC"} -xref: PMID:22204399 {source="Europe PMC"} -xref: PMID:22267186 {source="Europe PMC"} -xref: PMID:22296037 {source="Europe PMC"} -xref: PMID:22364556 {source="Europe PMC"} -xref: PMID:22435616 {source="Europe PMC"} -xref: PPDB:606 -xref: Reaxys:2037554 {source="Reaxys"} -xref: Wikipedia:Sulfuric_acid -is_a: CHEBI:33402 ! sulfur oxoacid -relationship: is_conjugate_acid_of CHEBI:45696 ! hydrogensulfate -relationship: RO:0000087 CHEBI:35223 ! has role catalyst -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "H2O4S" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QAOWNCQODCNURD-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "98.07948" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "97.96738" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OS(=O)(=O)O[H]" xsd:string - -[Term] -id: CHEBI:26873 -name: terpenoid -namespace: chebi_ontology -def: "Any isoprenoid that is a natural product or related compound formally derived from isoprene units. Terpenoids may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the parent terpene. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group." [] -subset: 3_STAR -synonym: "Terpenoid" EXACT [ChEBI] -synonym: "terpenoide" RELATED [IUPAC] -synonym: "terpenoides" RELATED [IUPAC] -synonym: "terpenoids" EXACT IUPAC_NAME [IUPAC] -xref: Wikipedia:Terpenoid -is_a: CHEBI:24913 ! isoprenoid -relationship: has_parent_hydride CHEBI:35186 ! terpene - -[Term] -id: CHEBI:26932 -name: tetrapyrrole -namespace: chebi_ontology -def: "A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [] -subset: 3_STAR -synonym: "a tetrapyrrole" RELATED [UniProt] -synonym: "tetrapyrrole" EXACT IUPAC_NAME [IUPAC] -synonym: "tetrapyrroles" EXACT IUPAC_NAME [IUPAC] -is_a: CHEBI:33833 ! heteroarene -is_a: CHEBI:38077 ! polypyrrole - -[Term] -id: CHEBI:27027 -name: micronutrient -namespace: chebi_ontology -def: "Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions." [] -subset: 3_STAR -synonym: "micronutrients" RELATED [ChEBI] -synonym: "trace elements" RELATED [ChEBI] -xref: Wikipedia:Micronutrient -is_a: CHEBI:33284 ! nutrient - -[Term] -id: CHEBI:27081 -name: transition element atom -namespace: chebi_ontology -def: "An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell." [] -subset: 3_STAR -synonym: "metal de transicion" RELATED [ChEBI] -synonym: "metal de transition" RELATED [ChEBI] -synonym: "metales de transicion" RELATED [ChEBI] -synonym: "metaux de transition" RELATED [ChEBI] -synonym: "transition element" EXACT IUPAC_NAME [IUPAC] -synonym: "transition element" RELATED [ChEBI] -synonym: "transition elements" RELATED [ChEBI] -synonym: "transition metal" RELATED [ChEBI] -synonym: "transition metals" RELATED [ChEBI] -synonym: "Uebergangselement" RELATED [ChEBI] -synonym: "Uebergangsmetalle" RELATED [ChEBI] -is_a: CHEBI:33521 ! metal atom - -[Term] -id: CHEBI:27162 -name: tryptamines -namespace: chebi_ontology -def: "Tryptamine and its substitution derivatives." [ANON:ANON] -subset: 3_STAR -is_a: CHEBI:24828 ! indoles - -[Term] -id: CHEBI:27171 -name: organic heterobicyclic compound -namespace: chebi_ontology -subset: 3_STAR -synonym: "heterobicyclic compounds" RELATED [ChEBI:] -synonym: "heterobicyclic compounds" RELATED [ChEBI] -synonym: "organic heterobicyclic compounds" RELATED [ChEBI] -synonym: "organic heterobicyclic compounds" RELATED [ChEBI:] -is_a: CHEBI:33672 ! heterobicyclic compound -is_a: CHEBI:38166 ! organic heteropolycyclic compound - -[Term] -id: CHEBI:27207 -name: univalent carboacyl group -namespace: chebi_ontology -def: "A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid." [] -subset: 3_STAR -synonym: "univalent acyl group" RELATED [ChEBI] -synonym: "univalent carboacyl groups" RELATED [ChEBI] -synonym: "univalent carboxylic acyl groups" RELATED [ChEBI] -is_a: CHEBI:37838 ! carboacyl group - -[Term] -id: CHEBI:27369 -name: zwitterion -namespace: chebi_ontology -def: "A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer)." [] -subset: 3_STAR -synonym: "compose zwitterionique" RELATED [IUPAC] -synonym: "compuestos zwitterionicos" RELATED [IUPAC] -synonym: "zwitterion" EXACT IUPAC_NAME [IUPAC] -synonym: "zwitteriones" RELATED [IUPAC] -synonym: "zwitterionic compounds" RELATED [IUPAC] -synonym: "zwitterions" EXACT IUPAC_NAME [IUPAC] -is_a: CHEBI:51151 ! dipolar compound - -[Term] -id: CHEBI:27584 -name: aldosterone -namespace: chebi_ontology -alt_id: CHEBI:22306 -alt_id: CHEBI:2563 -alt_id: CHEBI:40919 -def: "A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney." [] -subset: 3_STAR -synonym: "(+)-aldosterone" RELATED [NIST_Chemistry_WebBook] -synonym: "(11beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al" RELATED [NIST_Chemistry_WebBook] -synonym: "11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al" RELATED [KEGG_COMPOUND] -synonym: "11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al" EXACT IUPAC_NAME [IUPAC] -synonym: "ALDOSTERONE" EXACT [PDBeChem] -synonym: "Aldosterone" EXACT [KEGG_COMPOUND] -synonym: "aldosterone" EXACT [UniProt] -xref: Beilstein:3224996 {source="ChemIDplus"} -xref: CAS:52-39-1 {source="ChemIDplus"} -xref: CAS:52-39-1 {source="NIST Chemistry WebBook"} -xref: CAS:52-39-1 {source="KEGG COMPOUND"} -xref: Drug_Central:111 {source="DrugCentral"} -xref: DrugBank:DB04630 -xref: HMDB:HMDB0000037 -xref: KEGG:C01780 -xref: LINCS:LSM-42770 -xref: LIPID_MAPS_instance:LMST02030026 {source="LIPID MAPS"} -xref: PDBeChem:AS4 -xref: PMID:10438974 {source="Europe PMC"} -xref: Reaxys:3224996 {source="Reaxys"} -xref: Wikipedia:Aldosterone -is_a: CHEBI:131565 ! steroid aldehyde -is_a: CHEBI:139590 ! primary alpha-hydroxy ketone -is_a: CHEBI:25354 ! mineralocorticoid -is_a: CHEBI:35344 ! 21-hydroxy steroid -is_a: CHEBI:35346 ! 11beta-hydroxy steroid -is_a: CHEBI:36885 ! 20-oxo steroid -is_a: CHEBI:36887 ! 18-oxo steroid -is_a: CHEBI:47909 ! 3-oxo-Delta(4) steroid -is_a: CHEBI:64600 ! C21-steroid hormone -relationship: has_parent_hydride CHEBI:8386 ! pregnane -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C21H28O5" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "PQSUYGKTWSAVDQ-ZVIOFETBSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "360.44400" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "360.19367" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]12C=O)C(=O)CO" xsd:string - -[Term] -id: CHEBI:27594 -name: carbon atom -namespace: chebi_ontology -alt_id: CHEBI:23009 -alt_id: CHEBI:3399 -subset: 3_STAR -synonym: "6C" RELATED [IUPAC] -synonym: "C" RELATED [KEGG_COMPOUND] -synonym: "C" RELATED [IUPAC] -synonym: "Carbon" RELATED [KEGG_COMPOUND] -synonym: "carbon" EXACT IUPAC_NAME [IUPAC] -synonym: "carbon" RELATED [ChEBI] -synonym: "carbone" RELATED [ChEBI] -synonym: "carbonium" RELATED [ChEBI] -synonym: "carbono" RELATED [ChEBI] -synonym: "Kohlenstoff" RELATED [ChEBI] -xref: CAS:7440-44-0 {source="ChemIDplus"} -xref: CAS:7440-44-0 {source="KEGG COMPOUND"} -xref: KEGG:C06265 -xref: WebElements:C -is_a: CHEBI:25585 ! nonmetal atom -is_a: CHEBI:33306 ! carbon group element atom -relationship: RO:0000087 CHEBI:33937 ! has role macronutrient -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OKTJSMMVPCPJKN-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "12.01070" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "12.00000" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[C]" xsd:string - -[Term] -id: CHEBI:28087 -name: glycogen -namespace: chebi_ontology -alt_id: CHEBI:24379 -alt_id: CHEBI:5466 -def: "A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some cumulative alpha(1->6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues." [] -subset: 3_STAR -synonym: "animal starch" RELATED [ChemIDplus] -synonym: "Glycogen" EXACT [KEGG_COMPOUND] -synonym: "liver starch" RELATED [ChemIDplus] -synonym: "WURCS=2.0/1,4,3/[a2122h-1a_1-5]/1-1-1-1/a4-b1_b4-c1_b6-d1" RELATED [GlyTouCan] -xref: CAS:9005-79-2 {source="KEGG COMPOUND"} -xref: CAS:9005-79-2 {source="ChemIDplus"} -xref: GlyGen:G99991IU -xref: GlyTouCan:G99991IU -xref: HMDB:HMDB0000757 -xref: KEGG:C00182 -xref: MetaCyc:CPD0-971 -xref: Wikipedia:Glycogen -is_a: CHEBI:24384 ! glycogens -relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite -relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite - -[Term] -id: CHEBI:28616 -name: carbamic acid -namespace: chebi_ontology -alt_id: CHEBI:22504 -alt_id: CHEBI:23002 -alt_id: CHEBI:3386 -alt_id: CHEBI:44573 -def: "A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised." [] -subset: 3_STAR -synonym: "Aminoameisensaeure" RELATED [ChEBI] -synonym: "Aminoformic acid" RELATED [KEGG_COMPOUND] -synonym: "Carbamate" RELATED [KEGG_COMPOUND] -synonym: "CARBAMIC ACID" EXACT [PDBeChem] -synonym: "Carbamic acid" EXACT [KEGG_COMPOUND] -synonym: "carbamic acid" EXACT IUPAC_NAME [IUPAC] -synonym: "Carbamidsaeure" RELATED [ChEBI] -xref: Beilstein:1734754 {source="Beilstein"} -xref: CAS:463-77-4 {source="KEGG COMPOUND"} -xref: CAS:463-77-4 {source="ChemIDplus"} -xref: DrugBank:DB04261 -xref: Gmelin:130345 {source="Gmelin"} -xref: KEGG:C01563 -xref: PDBeChem:OUT -xref: Wikipedia:Carbamic_acid -is_a: CHEBI:35352 ! organonitrogen compound -is_a: CHEBI:35605 ! carbon oxoacid -is_a: CHEBI:64708 ! one-carbon compound -relationship: is_conjugate_acid_of CHEBI:13941 ! carbamate -relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CH3NO2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KXDHJXZQYSOELW-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "61.04006" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "61.01638" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(O)=O" xsd:string - -[Term] -id: CHEBI:28659 -name: phosphorus atom -namespace: chebi_ontology -alt_id: CHEBI:26080 -alt_id: CHEBI:8168 -subset: 3_STAR -synonym: "15P" RELATED [IUPAC] -synonym: "fosforo" RELATED [ChEBI] -synonym: "P" RELATED [IUPAC] -synonym: "P" RELATED [KEGG_COMPOUND] -synonym: "Phosphor" RELATED [ChEBI] -synonym: "phosphore" RELATED [ChEBI] -synonym: "Phosphorus" RELATED [KEGG_COMPOUND] -synonym: "phosphorus" EXACT IUPAC_NAME [IUPAC] -synonym: "phosphorus" RELATED [ChEBI] -xref: CAS:7723-14-0 {source="ChemIDplus"} -xref: CAS:7723-14-0 {source="KEGG COMPOUND"} -xref: Gmelin:16235 {source="Gmelin"} -xref: KEGG:C06262 -xref: WebElements:P -is_a: CHEBI:25585 ! nonmetal atom -is_a: CHEBI:33300 ! pnictogen -relationship: RO:0000087 CHEBI:33937 ! has role macronutrient -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "P" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/P" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OAICVXFJPJFONN-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "30.97376" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "30.97376" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[P]" xsd:string - -[Term] -id: CHEBI:28790 -name: serotonin -namespace: chebi_ontology -alt_id: CHEBI:1420 -alt_id: CHEBI:26652 -alt_id: CHEBI:49894 -def: "A primary amino compound that is the 5-hydroxy derivative of tryptamine." [] -def: "The 5-hydroxy derivative of tryptamine." [ANON:ANON] -subset: 3_STAR -synonym: "3-(2-Aminoethyl)-1H-indol-5-ol" RELATED [KEGG COMPOUND:] -synonym: "3-(2-Aminoethyl)-1H-indol-5-ol" RELATED [KEGG_COMPOUND] -synonym: "3-(2-aminoethyl)-1H-indol-5-ol" EXACT IUPAC_NAME [IUPAC:] -synonym: "3-(2-aminoethyl)-1H-indol-5-ol" EXACT IUPAC_NAME [IUPAC] -synonym: "5-HT" RELATED [IUPHAR:] -synonym: "5-HT" RELATED [IUPHAR] -synonym: "5-Hydroxytryptamine" RELATED [KEGG COMPOUND:] -synonym: "5-Hydroxytryptamine" RELATED [KEGG_COMPOUND] -synonym: "C10H12N2O" RELATED FORMULA [KEGG COMPOUND:] -synonym: "Enteramine" RELATED [KEGG COMPOUND:] -synonym: "Enteramine" RELATED [KEGG_COMPOUND] -synonym: "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2" RELATED InChI [ChEBI:] -synonym: "InChIKey=QZAYGJVTTNCVMB-UHFFFAOYSA-N" RELATED InChIKey [ChEBI:] -synonym: "NCCc1c[nH]c2ccc(O)cc12" RELATED SMILES [ChEBI:] -synonym: "SEROTONIN" EXACT [PDBeChem:] -synonym: "SEROTONIN" EXACT [PDBeChem] -synonym: "Serotonin" EXACT [KEGG COMPOUND:] -synonym: "Serotonin" EXACT [KEGG_COMPOUND] -synonym: "serotonine" RELATED [ChEBI:] -synonym: "serotonine" RELATED [ChEBI] -synonym: "thrombocytin" RELATED [ChemIDplus:] -synonym: "thrombocytin" RELATED [ChemIDplus] -synonym: "thrombotonin" RELATED [ChemIDplus] -synonym: "thrombotonin" RELATED [ChemIDplus:] -xref: Beilstein:143524 {source="Beilstein"} -xref: CAS:50-67-9 {source="KEGG COMPOUND"} -xref: CAS:50-67-9 {source="ChemIDplus"} -xref: Gmelin:1861995 {source="Gmelin"} -xref: HMDB:HMDB0000259 -xref: KEGG:C00780 -xref: KNApSAcK:C00001429 -xref: LINCS:LSM-6589 -xref: MetaCyc:SEROTONIN -xref: PDBeChem:SRO -xref: PMID:18593914 {source="Europe PMC"} -xref: PMID:22770225 {source="Europe PMC"} -xref: PMID:24136337 {source="Europe PMC"} -xref: Reaxys:143524 {source="Reaxys"} -xref: Wikipedia:Serotonin -is_a: CHEBI:25375 ! monoamine molecular messenger -is_a: CHEBI:27162 ! tryptamines -is_a: CHEBI:33853 ! phenols -is_a: CHEBI:50994 ! primary amino compound -is_a: CHEBI:84729 ! hydroxyindoles -relationship: has_functional_parent CHEBI:16765 ! tryptamine -relationship: is_conjugate_base_of CHEBI:350546 ! serotonin(1+) -relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H12N2O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QZAYGJVTTNCVMB-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "176.215" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "176.09496" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1=CC(=CC=2C(=CNC12)CCN)O" xsd:string - -[Term] -id: CHEBI:28868 -name: fatty acid anion -namespace: chebi_ontology -alt_id: CHEBI:13634 -alt_id: CHEBI:24022 -alt_id: CHEBI:4985 -def: "The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid." [] -subset: 3_STAR -synonym: "a fatty acid" RELATED [UniProt] -synonym: "acido graso anionico" RELATED [ChEBI] -synonym: "acidos grasos anionicos" RELATED [ChEBI] -synonym: "Alkanate" RELATED [KEGG_COMPOUND] -synonym: "anion de l'acide gras" RELATED [ChEBI] -synonym: "Fatty acid anion" EXACT [KEGG_COMPOUND] -synonym: "fatty acid anions" RELATED [ChEBI] -synonym: "Fettsaeureanion" RELATED [ChEBI] -synonym: "Fettsaeureanionen" RELATED [ChEBI] -xref: KEGG:C02403 -xref: PMID:18628202 {source="Europe PMC"} -is_a: CHEBI:18059 ! lipid -is_a: CHEBI:35757 ! monocarboxylic acid anion -relationship: is_conjugate_base_of CHEBI:35366 ! fatty acid -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "44.00950" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([*])=O" xsd:string - -[Term] -id: CHEBI:28938 -name: ammonium -namespace: chebi_ontology -alt_id: CHEBI:22534 -alt_id: CHEBI:49783 -alt_id: CHEBI:7435 -def: "An onium cation obtained by protonation of ammonia." [] -subset: 3_STAR -synonym: "[NH4](+)" RELATED [MolBase] -synonym: "ammonium" EXACT IUPAC_NAME [IUPAC] -synonym: "ammonium" EXACT [ChEBI] -synonym: "ammonium cation" RELATED [ChemIDplus] -synonym: "ammonium ion" RELATED [PDBeChem] -synonym: "Ammonium(1+)" RELATED [ChemIDplus] -synonym: "azanium" EXACT IUPAC_NAME [IUPAC] -synonym: "NH4(+)" RELATED [UniProt] -synonym: "NH4(+)" RELATED [IUPAC] -synonym: "NH4+" RELATED [KEGG_COMPOUND] -xref: CAS:14798-03-9 {source="NIST Chemistry WebBook"} -xref: CAS:14798-03-9 {source="ChemIDplus"} -xref: Gmelin:84 {source="Gmelin"} -xref: KEGG:C01342 -xref: MetaCyc:AMMONIUM -xref: MolBase:929 -xref: PDBeChem:NH4 -xref: PMID:11319011 {source="Europe PMC"} -xref: PMID:11341317 {source="Europe PMC"} -xref: PMID:12096804 {source="Europe PMC"} -xref: PMID:14512268 {source="Europe PMC"} -xref: PMID:14879753 {source="Europe PMC"} -xref: PMID:16345391 {source="Europe PMC"} -xref: PMID:16903292 {source="Europe PMC"} -xref: PMID:17392693 {source="Europe PMC"} -xref: PMID:18515490 {source="Europe PMC"} -xref: PMID:19199063 {source="Europe PMC"} -xref: PMID:19596600 {source="Europe PMC"} -xref: PMID:19682559 {source="Europe PMC"} -xref: PMID:19716251 {source="Europe PMC"} -xref: PMID:21993530 {source="Europe PMC"} -xref: PMID:22265469 {source="Europe PMC"} -xref: PMID:22524020 {source="Europe PMC"} -xref: PMID:22562341 {source="Europe PMC"} -xref: PMID:22631217 {source="Europe PMC"} -xref: Reaxys:16093784 {source="Reaxys"} -xref: Wikipedia:Ammonium -is_a: CHEBI:35106 ! nitrogen hydride -is_a: CHEBI:50313 ! onium cation -is_a: CHEBI:60242 ! monovalent inorganic cation -relationship: is_conjugate_acid_of CHEBI:16134 ! ammonia -relationship: RO:0000087 CHEBI:23357 ! has role cofactor -relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite -relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "H4N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3N/h1H3/p+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QGZKDVFQNNGYKY-UHFFFAOYSA-O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "18.03850" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "18.03383" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][N+]([H])([H])[H]" xsd:string - -[Term] -id: CHEBI:28965 -name: dicarboxylic acid dianion -namespace: chebi_ontology -alt_id: CHEBI:13632 -alt_id: CHEBI:23688 -alt_id: CHEBI:23689 -alt_id: CHEBI:38711 -def: "A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid." [] -subset: 3_STAR -synonym: "a dicarboxylate" RELATED [UniProt] -synonym: "dicarboxylate" RELATED [ChEBI] -synonym: "dicarboxylates" RELATED [ChEBI] -synonym: "dicarboxylic acid dianion" EXACT [ChEBI] -synonym: "dicarboxylic acid dianions" RELATED [ChEBI] -is_a: CHEBI:35693 ! dicarboxylic acid anion -is_a: CHEBI:38716 ! carboxylic acid dianion -property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2O4R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "88.019" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "87.97966" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C(=O)[*]C([O-])=O" xsd:string - -[Term] -id: CHEBI:28976 -name: carbonic acid -namespace: chebi_ontology -alt_id: CHEBI:13351 -alt_id: CHEBI:23017 -alt_id: CHEBI:23744 -alt_id: CHEBI:3401 -subset: 3_STAR -synonym: "[CO(OH)2]" RELATED [IUPAC] -synonym: "Carbonic acid" EXACT [KEGG_COMPOUND] -synonym: "carbonic acid" EXACT IUPAC_NAME [IUPAC] -synonym: "Dihydrogen carbonate" RELATED [KEGG_COMPOUND] -synonym: "dihydroxidooxidocarbon" EXACT IUPAC_NAME [IUPAC] -synonym: "H2CO3" RELATED [KEGG_COMPOUND] -synonym: "H2CO3" RELATED [IUPAC] -synonym: "Koehlensaeure" RELATED [ChEBI] -xref: CAS:463-79-6 {source="ChemIDplus"} -xref: CAS:463-79-6 {source="KEGG COMPOUND"} -xref: Gmelin:25554 {source="Gmelin"} -xref: KEGG:C01353 -xref: PDBeChem:CO3 -is_a: CHEBI:35605 ! carbon oxoacid -is_a: CHEBI:36961 ! chalcocarbonic acid -relationship: is_conjugate_acid_of CHEBI:17544 ! hydrogencarbonate -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2O3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "62.02478" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "62.00039" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC(O)=O" xsd:string - -[Term] -id: CHEBI:29057 -name: keratan -namespace: chebi_ontology -alt_id: CHEBI:14490 -alt_id: CHEBI:24954 -subset: 1_STAR -is_a: CHEBI:18085 ! glycosaminoglycan - -[Term] -id: CHEBI:29067 -name: carboxylic acid anion -namespace: chebi_ontology -alt_id: CHEBI:13626 -alt_id: CHEBI:13945 -alt_id: CHEBI:23026 -alt_id: CHEBI:58657 -def: "The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated." [] -subset: 3_STAR -synonym: "a carboxylate" RELATED [UniProt] -synonym: "carboxylic acid anions" RELATED [ChEBI] -synonym: "carboxylic anions" RELATED [ChEBI] -is_a: CHEBI:25696 ! organic anion -is_a: CHEBI:35406 ! oxoanion -relationship: is_conjugate_base_of CHEBI:33575 ! carboxylic acid -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "44.00950" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([*])=O" xsd:string - -[Term] -id: CHEBI:29101 -name: sodium(1+) -namespace: chebi_ontology -alt_id: CHEBI:26717 -alt_id: CHEBI:49766 -alt_id: CHEBI:9175 -def: "A monoatomic monocation obtained from sodium." [] -subset: 3_STAR -synonym: "Na(+)" RELATED [UniProt] -synonym: "Na(+)" RELATED [IUPAC] -synonym: "Na+" RELATED [KEGG_COMPOUND] -synonym: "sodium cation" EXACT IUPAC_NAME [IUPAC] -synonym: "SODIUM ION" RELATED [PDBeChem] -synonym: "sodium(1+)" EXACT IUPAC_NAME [IUPAC] -synonym: "sodium(1+) ion" EXACT IUPAC_NAME [IUPAC] -synonym: "sodium(I) cation" EXACT IUPAC_NAME [IUPAC] -xref: CAS:17341-25-2 {source="ChemIDplus"} -xref: CAS:17341-25-2 {source="NIST Chemistry WebBook"} -xref: Gmelin:15196 {source="Gmelin"} -xref: KEGG:C01330 -xref: PDBeChem:NA -is_a: CHEBI:25414 ! monoatomic monocation -is_a: CHEBI:33504 ! alkali metal cation -is_a: CHEBI:37246 ! elemental sodium -is_a: CHEBI:60242 ! monovalent inorganic cation -relationship: RO:0000087 CHEBI:23357 ! has role cofactor -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "Na" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Na/q+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "FKNQFGJONOIPTF-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "22.98977" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "22.98922" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Na+]" xsd:string - -[Term] -id: CHEBI:29108 -name: calcium(2+) -namespace: chebi_ontology -alt_id: CHEBI:22988 -alt_id: CHEBI:3308 -alt_id: CHEBI:48760 -subset: 3_STAR -synonym: "Ca(2+)" RELATED [IUPAC] -synonym: "Ca(2+)" RELATED [UniProt] -synonym: "Ca2+" RELATED [KEGG_COMPOUND] -synonym: "CALCIUM ION" RELATED [PDBeChem] -synonym: "calcium(2+)" EXACT IUPAC_NAME [IUPAC] -synonym: "calcium(2+) ion" EXACT IUPAC_NAME [IUPAC] -synonym: "calcium(II) cation" EXACT IUPAC_NAME [IUPAC] -synonym: "calcium, doubly charged positive ion" RELATED [NIST_Chemistry_WebBook] -xref: CAS:14127-61-8 {source="ChemIDplus"} -xref: CAS:14127-61-8 {source="NIST Chemistry WebBook"} -xref: Gmelin:6850 {source="Gmelin"} -xref: KEGG:C00076 -xref: PDBeChem:CA -is_a: CHEBI:30412 ! monoatomic dication -is_a: CHEBI:39123 ! calcium cation -is_a: CHEBI:60240 ! divalent metal cation -relationship: RO:0000087 CHEBI:23357 ! has role cofactor -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "+2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "Ca" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Ca/q+2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BHPQYMZQTOCNFJ-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "40.07800" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "39.96149" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Ca++]" xsd:string - -[Term] -id: CHEBI:29337 -name: azanide -namespace: chebi_ontology -subset: 3_STAR -synonym: "amide" EXACT IUPAC_NAME [IUPAC] -synonym: "azanide" EXACT IUPAC_NAME [IUPAC] -synonym: "dihydridonitrate(1-)" EXACT IUPAC_NAME [IUPAC] -synonym: "NH2(-)" RELATED [IUPAC] -is_a: CHEBI:35106 ! nitrogen hydride -is_a: CHEBI:79389 ! monovalent inorganic anion -relationship: is_conjugate_acid_of CHEBI:29340 ! hydridonitrate(2-) -relationship: is_conjugate_base_of CHEBI:16134 ! ammonia -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "H2N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2N/h1H2/q-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "HYGWNUKOUCZBND-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "16.02262" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "16.01927" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][N-][H]" xsd:string - -[Term] -id: CHEBI:29340 -name: hydridonitrate(2-) -namespace: chebi_ontology -def: "A divalent inorganic anion resulting from the removal of two protons from ammonia." [] -subset: 3_STAR -synonym: "azanediide" EXACT IUPAC_NAME [IUPAC] -synonym: "hydridonitrate(2-)" EXACT IUPAC_NAME [IUPAC] -synonym: "imide" RELATED [IUPAC] -synonym: "NH(2-)" RELATED [IUPAC] -is_a: CHEBI:35106 ! nitrogen hydride -is_a: CHEBI:79388 ! divalent inorganic anion -relationship: is_conjugate_base_of CHEBI:29337 ! azanide -property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "HN" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/HN/h1H/q-2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "DZQYTNGKSBCIOE-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "15.01468" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.01200" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[N--][H]" xsd:string - -[Term] -id: CHEBI:29412 -name: oxonium -namespace: chebi_ontology -subset: 3_STAR -synonym: "[OH3](+)" RELATED [MolBase] -synonym: "aquahydrogen(1+)" EXACT IUPAC_NAME [IUPAC] -synonym: "H3O(+)" RELATED [IUPAC] -synonym: "Hydronium cation" RELATED [NIST_Chemistry_WebBook] -synonym: "Hydronium ion" RELATED [ChemIDplus] -synonym: "oxidanium" EXACT IUPAC_NAME [IUPAC] -synonym: "oxonium" EXACT IUPAC_NAME [IUPAC] -synonym: "trihydridooxygen(1+)" EXACT IUPAC_NAME [IUPAC] -xref: CAS:13968-08-6 {source="ChemIDplus"} -xref: CAS:13968-08-6 {source="NIST Chemistry WebBook"} -xref: Gmelin:141 {source="Gmelin"} -xref: MolBase:1646 -is_a: CHEBI:33693 ! oxygen hydride -is_a: CHEBI:50313 ! onium cation -relationship: is_conjugate_acid_of CHEBI:15377 ! water -property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "H3O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O/h1H2/p+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "XLYOFNOQVPJJNP-UHFFFAOYSA-O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "19.02322" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "19.01784" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][O+]([H])[H]" xsd:string - -[Term] -id: CHEBI:29793 -name: hydridodioxygen(1+) -namespace: chebi_ontology -subset: 3_STAR -synonym: "[HO2](+)" RELATED [ChEBI] -synonym: "dioxidenium" EXACT IUPAC_NAME [IUPAC] -synonym: "HO2(+)" RELATED [IUPAC] -synonym: "HOO(+)" RELATED [ChEBI] -synonym: "hydridodioxygen(1+)" EXACT IUPAC_NAME [IUPAC] -xref: Gmelin:508 {source="Gmelin"} -is_a: CHEBI:33693 ! oxygen hydride -relationship: is_conjugate_acid_of CHEBI:15379 ! dioxygen -property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "HO2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/O2/c1-2/p+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "MYMOFIZGZYHOMD-UHFFFAOYSA-O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "33.00674" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "32.99711" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][O+]=O" xsd:string - -[Term] -id: CHEBI:29987 -name: glutamate(2-) -namespace: chebi_ontology -def: "A dicarboxylic acid dianion that is the conjugate base of glutamate(1-)." [] -subset: 3_STAR -synonym: "2-aminopentanedioate" EXACT IUPAC_NAME [IUPAC] -synonym: "glutamate" EXACT IUPAC_NAME [IUPAC] -synonym: "glutamate(2-)" EXACT [JCBN] -synonym: "glutamic acid dianion" RELATED [JCBN] -xref: Beilstein:4134100 {source="Beilstein"} -xref: Gmelin:327903 {source="Gmelin"} -xref: Reaxys:4134100 {source="Reaxys"} -is_a: CHEBI:28965 ! dicarboxylic acid dianion -relationship: is_conjugate_base_of CHEBI:14321 ! glutamate(1-) -relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H7NO4" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "WHUUTDBJXJRKMK-UHFFFAOYSA-L" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "145.11342" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "145.03860" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(CCC([O-])=O)C([O-])=O" xsd:string - -[Term] -id: CHEBI:30089 -name: acetate -namespace: chebi_ontology -alt_id: CHEBI:13704 -alt_id: CHEBI:22165 -alt_id: CHEBI:40480 -def: "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid." [] -subset: 3_STAR -synonym: "acetate" EXACT [UniProt] -synonym: "acetate" EXACT IUPAC_NAME [IUPAC] -synonym: "ACETATE ION" RELATED [PDBeChem] -synonym: "acetic acid, ion(1-)" RELATED [ChemIDplus] -synonym: "Azetat" RELATED [ChEBI] -synonym: "CH3-COO(-)" RELATED [IUPAC] -synonym: "Ethanoat" RELATED [ChEBI] -synonym: "ethanoate" RELATED [ChEBI] -synonym: "MeCO2 anion" RELATED [NIST_Chemistry_WebBook] -xref: Beilstein:1901470 {source="Beilstein"} -xref: CAS:71-50-1 {source="ChemIDplus"} -xref: CAS:71-50-1 {source="NIST Chemistry WebBook"} -xref: DrugBank:DB03166 -xref: Gmelin:1379 {source="Gmelin"} -xref: KEGG:C00033 -xref: MetaCyc:ACET -xref: PDBeChem:ACT -xref: PMID:17190852 {source="Europe PMC"} -xref: PMID:22211106 {source="Europe PMC"} -xref: PMID:22371380 {source="Europe PMC"} -xref: Reaxys:1901470 {source="Reaxys"} -xref: UM-BBD_compID:c0050 {source="UM-BBD"} -xref: Wikipedia:Acetate -is_a: CHEBI:35757 ! monocarboxylic acid anion -relationship: is_conjugate_base_of CHEBI:15366 ! acetic acid -relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H3O2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QTBSBXVTEAMEQO-UHFFFAOYSA-M" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "59.04402" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "59.01385" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC([O-])=O" xsd:string - -[Term] -id: CHEBI:30212 -name: photon -namespace: chebi_ontology -alt_id: CHEBI:10581 -alt_id: CHEBI:14383 -def: "Particle of zero charge, zero rest mass, spin quantum number 1, energy hnu and momentum hnu/c (h is the Planck constant, nu the frequency of radiation and c the speed of light), carrier of electromagnetic force." [] -subset: 3_STAR -synonym: "foton" RELATED [ChEBI] -synonym: "gamma" RELATED [IUPAC] -synonym: "hnu" RELATED [IUPAC] -synonym: "hnu" RELATED [UniProt] -synonym: "Lichtquant" RELATED [ChEBI] -synonym: "Light" RELATED [KEGG_COMPOUND] -synonym: "light quantum" RELATED [ChEBI] -synonym: "photon" EXACT IUPAC_NAME [IUPAC] -xref: KEGG:C00205 -is_a: CHEBI:36341 ! boson -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "0.0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "0.0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "*" xsd:string - -[Term] -id: CHEBI:30412 -name: monoatomic dication -namespace: chebi_ontology -alt_id: CHEBI:23856 -alt_id: CHEBI:4665 -subset: 3_STAR -synonym: "Divalent cation" RELATED [KEGG_COMPOUND] -synonym: "divalent inorganic cations" RELATED [ChEBI] -synonym: "monoatomic dications" RELATED [ChEBI] -xref: KEGG:C00572 -is_a: CHEBI:23906 ! monoatomic cation -property_value: http://purl.obolibrary.org/obo/chebi/charge "+2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "0.00000" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*++]" xsd:string - -[Term] -id: CHEBI:30566 -name: gamma-aminobutyrate -namespace: chebi_ontology -alt_id: CHEBI:11961 -alt_id: CHEBI:20317 -def: "An gamma-amino acid anion resulting from the deprotonation of the carboxy group of gamma-aminobutyric acid." [] -subset: 3_STAR -synonym: "4-Amino-butyrat" RELATED [ChEBI] -synonym: "4-aminobutanoate" EXACT IUPAC_NAME [IUPAC] -synonym: "4-aminobutanoic acid ion (1-)" RELATED [ChEBI] -synonym: "4-Aminobutylate" RELATED [KEGG_COMPOUND] -synonym: "4-aminobutyrate" RELATED [ChEBI] -synonym: "gamma-aminobutanoate" RELATED [ChEBI] -synonym: "gamma-aminobutyrate anion" RELATED [ChEBI] -xref: Beilstein:3536873 {source="Beilstein"} -xref: Gmelin:559138 {source="Gmelin"} -xref: KEGG:C00334 -xref: PMID:12509893 {source="Europe PMC"} -xref: Reaxys:3536873 {source="Reaxys"} -is_a: CHEBI:71666 ! gamma-amino acid anion -relationship: has_functional_parent CHEBI:17968 ! butyrate -relationship: is_conjugate_base_of CHEBI:16865 ! gamma-aminobutyric acid -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H8NO2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)/p-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BTCSSZJGUNDROE-UHFFFAOYSA-M" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "102.11186" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "102.05605" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "NCCCC([O-])=O" xsd:string - -[Term] -id: CHEBI:30751 -name: formic acid -namespace: chebi_ontology -alt_id: CHEBI:24082 -alt_id: CHEBI:42460 -alt_id: CHEBI:5145 -def: "The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects." [] -subset: 3_STAR -synonym: "Acide formique" RELATED [ChemIDplus] -synonym: "Ameisensaeure" RELATED [ChemIDplus] -synonym: "aminic acid" RELATED [ChemIDplus] -synonym: "bilorin" RELATED [ChemIDplus] -synonym: "FORMIC ACID" EXACT [PDBeChem] -synonym: "Formic acid" EXACT [KEGG_COMPOUND] -synonym: "formic acid" EXACT IUPAC_NAME [IUPAC] -synonym: "formylic acid" RELATED [ChemIDplus] -synonym: "H-COOH" RELATED [IUPAC] -synonym: "HCO2H" RELATED [ChEBI] -synonym: "HCOOH" RELATED [NIST_Chemistry_WebBook] -synonym: "hydrogen carboxylic acid" RELATED [ChemIDplus] -synonym: "Methanoic acid" RELATED [KEGG_COMPOUND] -synonym: "methoic acid" RELATED [ChEBI] -xref: Beilstein:1209246 {source="Beilstein"} -xref: BPDB:1749 -xref: CAS:64-18-6 {source="NIST Chemistry WebBook"} -xref: CAS:64-18-6 {source="ChemIDplus"} -xref: CAS:64-18-6 {source="KEGG COMPOUND"} -xref: DrugBank:DB01942 -xref: Gmelin:1008 {source="Gmelin"} -xref: HMDB:HMDB0000142 -xref: KEGG:C00058 -xref: KNApSAcK:C00001182 -xref: LIPID_MAPS_instance:LMFA01010040 {source="LIPID MAPS"} -xref: MetaCyc:FORMATE -xref: Patent:CN101481304 -xref: PDBeChem:FMT -xref: PMID:12591956 {source="Europe PMC"} -xref: PMID:14637377 {source="Europe PMC"} -xref: PMID:15811469 {source="Europe PMC"} -xref: PMID:16120414 {source="Europe PMC"} -xref: PMID:16185830 {source="Europe PMC"} -xref: PMID:16222862 {source="Europe PMC"} -xref: PMID:16230297 {source="Europe PMC"} -xref: PMID:16445901 {source="Europe PMC"} -xref: PMID:16465784 {source="Europe PMC"} -xref: PMID:18034701 {source="Europe PMC"} -xref: PMID:18397576 {source="Europe PMC"} -xref: PMID:22080171 {source="Europe PMC"} -xref: PMID:22280475 {source="Europe PMC"} -xref: PMID:22304812 {source="Europe PMC"} -xref: PMID:22385261 {source="Europe PMC"} -xref: PMID:22447125 {source="Europe PMC"} -xref: PMID:22483350 {source="Europe PMC"} -xref: PMID:22499553 {source="Europe PMC"} -xref: PMID:22540994 {source="Europe PMC"} -xref: PMID:22606986 {source="Europe PMC"} -xref: PMID:22622393 {source="Europe PMC"} -xref: PMID:3946945 {source="Europe PMC"} -xref: PMID:7361809 {source="Europe PMC"} -xref: Reaxys:1209246 {source="Reaxys"} -xref: Wikipedia:Formic_acid -is_a: CHEBI:25384 ! monocarboxylic acid -relationship: is_conjugate_acid_of CHEBI:15740 ! formate -relationship: RO:0000087 CHEBI:25212 ! has role metabolite -relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent -relationship: RO:0000087 CHEBI:48356 ! has role protic solvent -relationship: RO:0000087 CHEBI:74783 ! has role astringent -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2O2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BDAGIHXWWSANSR-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "46.02538" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "46.00548" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]C(O)=O" xsd:string - -[Term] -id: CHEBI:30772 -name: butyric acid -namespace: chebi_ontology -alt_id: CHEBI:113450 -alt_id: CHEBI:22948 -alt_id: CHEBI:3234 -alt_id: CHEBI:41208 -def: "A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group." [] -subset: 3_STAR -synonym: "1-butanoic acid" RELATED [HMDB] -synonym: "1-butyric acid" RELATED [HMDB] -synonym: "1-propanecarboxylic acid" RELATED [MetaCyc] -synonym: "4:0" RELATED [ChEBI] -synonym: "acide butanoique" RELATED [IUPAC] -synonym: "acide butyrique" RELATED [ChEBI] -synonym: "butanic acid" RELATED [ChEBI] -synonym: "Butanoate" RELATED [KEGG_COMPOUND] -synonym: "BUTANOIC ACID" RELATED [PDBeChem] -synonym: "Butanoic acid" RELATED [KEGG_COMPOUND] -synonym: "butanoic acid" EXACT IUPAC_NAME [IUPAC] -synonym: "butoic acid" RELATED [ChEBI] -synonym: "Buttersaeure" RELATED [ChEBI] -synonym: "Butyric acid" EXACT [KEGG_COMPOUND] -synonym: "butyric acid" EXACT [IUPAC] -synonym: "C4:0" RELATED [ChEBI] -synonym: "CH3-[CH2]2-COOH" RELATED [IUPAC] -synonym: "ethylacetic acid" RELATED [NIST_Chemistry_WebBook] -synonym: "n-butanoic acid" RELATED [NIST_Chemistry_WebBook] -synonym: "n-butyric acid" RELATED [NIST_Chemistry_WebBook] -synonym: "propanecarboxylic acid" RELATED [HMDB] -synonym: "propylformic acid" RELATED [MetaCyc] -xref: Beilstein:906770 {source="Beilstein"} -xref: CAS:107-92-6 {source="ChemIDplus"} -xref: CAS:107-92-6 {source="NIST Chemistry WebBook"} -xref: CAS:107-92-6 {source="KEGG COMPOUND"} -xref: DrugBank:DB03568 -xref: Gmelin:26242 {source="Gmelin"} -xref: HMDB:HMDB0000039 -xref: KEGG:C00246 -xref: KNApSAcK:C00001180 -xref: LIPID_MAPS_instance:LMFA01010004 {source="LIPID MAPS"} -xref: MetaCyc:BUTYRIC_ACID -xref: PDBeChem:BUA -xref: PMID:10736622 {source="Europe PMC"} -xref: PMID:10956204 {source="ChEMBL"} -xref: PMID:11201044 {source="Europe PMC"} -xref: PMID:11208715 {source="Europe PMC"} -xref: PMID:11238216 {source="Europe PMC"} -xref: PMID:11305323 {source="Europe PMC"} -xref: PMID:12068484 {source="Europe PMC"} -xref: PMID:13678314 {source="Europe PMC"} -xref: PMID:14962641 {source="Europe PMC"} -xref: PMID:1542095 {source="ChEMBL"} -xref: PMID:15809727 {source="Europe PMC"} -xref: PMID:15810631 {source="Europe PMC"} -xref: PMID:15938880 {source="Europe PMC"} -xref: PMID:19318247 {source="Europe PMC"} -xref: PMID:19366864 {source="Europe PMC"} -xref: PMID:19703412 {source="Europe PMC"} -xref: PMID:21699495 {source="Europe PMC"} -xref: PMID:22038864 {source="Europe PMC"} -xref: PMID:22194341 {source="Europe PMC"} -xref: PMID:22322557 {source="Europe PMC"} -xref: PMID:22339023 {source="Europe PMC"} -xref: PMID:22466881 {source="Europe PMC"} -xref: Reaxys:906770 {source="Reaxys"} -xref: Wikipedia:Butyric_acid -is_a: CHEBI:140601 ! fatty acid 4:0 -is_a: CHEBI:39418 ! straight-chain saturated fatty acid -relationship: is_conjugate_acid_of CHEBI:17968 ! butyrate -relationship: RO:0000087 CHEBI:131604 ! has role Mycoplasma genitalium metabolite -relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H8O2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "FERIUCNNQQJTOY-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "88.10510" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "88.05243" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCCC(O)=O" xsd:string - -[Term] -id: CHEBI:30879 -name: alcohol -namespace: chebi_ontology -alt_id: CHEBI:13804 -alt_id: CHEBI:22288 -alt_id: CHEBI:2553 -def: "A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom." [ANON:ANON] -subset: 3_STAR -synonym: "Alcohol" EXACT [KEGG COMPOUND:] -synonym: "Alcohol" EXACT [KEGG_COMPOUND] -synonym: "alcohols" EXACT IUPAC_NAME [IUPAC] -synonym: "alcohols" EXACT IUPAC_NAME [IUPAC:] -synonym: "an alcohol" RELATED [UniProt] -synonym: "CHOR3" RELATED FORMULA [ChEBI:] -synonym: "HOR" RELATED FORMULA [KEGG COMPOUND:] -synonym: "OC([*])([*])[*]" RELATED SMILES [ChEBI:] -xref: KEGG:C00069 -is_a: CHEBI:33822 ! organic hydroxy compound -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "HOR" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "17.007" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "17.00274" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "O[*]" xsd:string - -[Term] -id: CHEBI:3098 -name: bile acid -namespace: chebi_ontology -def: "Any member of a group of hydroxy-5beta-cholanic acids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration." [] -subset: 3_STAR -synonym: "5beta-bile acid" RELATED [ChEBI] -synonym: "5beta-bile acids" RELATED [ChEBI] -synonym: "Bile acid" EXACT [KEGG_COMPOUND] -synonym: "bile acids" RELATED [ChEBI] -synonym: "Bile salt" RELATED [KEGG_COMPOUND] -synonym: "Gallensaeure" RELATED [ChEBI] -synonym: "Gallensaeuren" RELATED [ChEBI] -xref: KEGG:C01558 -is_a: CHEBI:138366 ! bile acids -is_a: CHEBI:24663 ! hydroxy-5beta-cholanic acid - -[Term] -id: CHEBI:32507 -name: glycinium -namespace: chebi_ontology -def: "An alpha-amino-acid cation that is the conjugate acid of glycine, arising from protonation of the amino." [] -subset: 3_STAR -synonym: "carboxymethanaminium" RELATED [IUPAC] -synonym: "glycine cation" RELATED [JCBN] -synonym: "glycinium" EXACT IUPAC_NAME [IUPAC] -synonym: "H2gly(+)" RELATED [IUPAC] -synonym: "NH3(+)-CH2-COOH" RELATED [IUPAC] -xref: Gmelin:323509 {source="Gmelin"} -is_a: CHEBI:33719 ! alpha-amino-acid cation -relationship: is_conjugate_acid_of CHEBI:15428 ! glycine -relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H6NO2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)/p+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "DHMQDGOQFOQNFH-UHFFFAOYSA-O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "76.07458" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "76.03930" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]CC(O)=O" xsd:string - -[Term] -id: CHEBI:32508 -name: glycinate -namespace: chebi_ontology -def: "An alpha-amino-acid anion that is the conjugate base of glycine, arising from deprotonation of the carboxy group." [] -subset: 3_STAR -synonym: "aminoacetate" RELATED [IUPAC] -synonym: "gly(-)" RELATED [IUPAC] -synonym: "glycinate" EXACT IUPAC_NAME [IUPAC] -synonym: "glycine anion" RELATED [JCBN] -synonym: "H2N-CH2-COO(-)" RELATED [IUPAC] -xref: Beilstein:1852023 {source="Beilstein"} -xref: Gmelin:81890 {source="Gmelin"} -xref: Reaxys:1852023 {source="Reaxys"} -xref: UM-BBD_compID:c0559 {source="UM-BBD"} -is_a: CHEBI:33558 ! alpha-amino-acid anion -relationship: is_conjugate_base_of CHEBI:15428 ! glycine -relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)/p-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "DHMQDGOQFOQNFH-UHFFFAOYSA-M" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "74.05870" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02475" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "NCC([O-])=O" xsd:string [Term] id: CHEBI:32952 -name: amine namespace: chebi_ontology -alt_id: CHEBI:13814 -alt_id: CHEBI:22474 -alt_id: CHEBI:2641 def: "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." [ANON:ANON] -subset: 3_STAR -synonym: "Amin" RELATED [ChEBI] synonym: "Amin" RELATED [ChEBI:] -synonym: "Amine" EXACT [KEGG_COMPOUND] synonym: "Amine" EXACT [KEGG COMPOUND:] synonym: "amines" EXACT IUPAC_NAME [IUPAC:] -synonym: "amines" EXACT IUPAC_NAME [IUPAC] synonym: "an amine" RELATED [UniProt:] -synonym: "Substituted amine" RELATED [KEGG_COMPOUND] -xref: KEGG:C00706 -is_a: CHEBI:50047 ! organic amino compound [Term] id: CHEBI:32988 -name: amide namespace: chebi_ontology -alt_id: CHEBI:22473 -alt_id: CHEBI:2633 def: "An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [ANON:ANON] -subset: 3_STAR -synonym: "Amide" EXACT [KEGG_COMPOUND] synonym: "Amide" EXACT [KEGG COMPOUND:] -synonym: "amides" EXACT IUPAC_NAME [IUPAC] synonym: "amides" EXACT IUPAC_NAME [IUPAC:] -xref: KEGG:C00241 -is_a: CHEBI:51143 ! nitrogen molecular entity - -[Term] -id: CHEBI:3306 -name: calcitonin -namespace: chebi_ontology -def: "A 32-membered heterodetic cyclic peptide comprising the sequence Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 cyclised by a disulfide bridge between the two Cys residues at positions 1 and 7." [] -subset: 3_STAR -synonym: "Calcitonin" EXACT [KEGG_COMPOUND] -synonym: "calcitonin" RELATED INN [ChemIDplus] -synonym: "Calcitonin, salmon" RELATED [KEGG_COMPOUND] -synonym: "Cibacalcin" RELATED [KEGG_COMPOUND] -synonym: "cyclo-[Cys-Ser-Asn-Leu-Ser-Thr-Cys]-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2" RELATED [ChEBI] -synonym: "N-{[(4R,7S,10S,13S,16S,19S,22R)-22-amino-16-(2-amino-2-oxoethyl)-7-[(1R)-1-hydroxyethyl]-10,19-bis(hydroxymethyl)-13-isobutyl-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosan-4-yl]carbonyl}-L-valyl-L-leucylglycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparaginyl-L-threonylglycyl-L-serylglycyl-L-threonyl-L-prolinamide" EXACT IUPAC_NAME [IUPAC] -synonym: "Salmon calcitonin" RELATED [ChemIDplus] -synonym: "Salmon calcitonin-(1-32)" RELATED [ChemIDplus] -synonym: "Salmotonin" RELATED [DrugBank] -synonym: "Thyrocalcitonin (salmon)" RELATED [ChemIDplus] -xref: CAS:47931-85-1 {source="ChemIDplus"} -xref: CAS:47931-85-1 {source="KEGG COMPOUND"} -xref: CAS:9007-12-9 {source="KEGG COMPOUND"} -xref: Drug_Central:2989 {source="DrugCentral"} -xref: DrugBank:DB00017 -xref: KEGG:C06865 -xref: KEGG:D00249 -xref: Reaxys:8186880 {source="Reaxys"} -xref: Wikipedia:Calcitonin -is_a: CHEBI:15841 ! polypeptide -is_a: CHEBI:24533 ! heterodetic cyclic peptide -is_a: CHEBI:25905 ! peptide hormone -relationship: RO:0000087 CHEBI:25212 ! has role metabolite -relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C145H240N44O48S2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C145H240N44O48S2/c1-65(2)45-86(175-139(232)110(70(11)12)183-136(229)99-63-239-238-62-79(148)117(210)178-96(59-191)134(227)174-92(52-104(151)202)131(224)172-90(49-69(9)10)129(222)180-98(61-193)135(228)187-114(74(16)197)142(235)181-99)118(211)158-55-106(204)162-80(25-18-20-40-146)120(213)169-89(48-68(7)8)128(221)179-97(60-192)133(226)167-83(34-37-102(149)200)122(215)165-85(36-39-109(207)208)123(216)171-88(47-67(5)6)127(220)173-91(51-77-54-156-64-161-77)130(223)164-81(26-19-21-41-147)121(214)170-87(46-66(3)4)126(219)166-84(35-38-103(150)201)125(218)186-113(73(15)196)141(234)177-94(50-76-30-32-78(199)33-31-76)143(236)189-44-24-29-101(189)137(230)168-82(27-22-42-157-145(154)155)124(217)185-112(72(14)195)140(233)176-93(53-105(152)203)132(225)184-111(71(13)194)138(231)160-56-107(205)163-95(58-190)119(212)159-57-108(206)182-115(75(17)198)144(237)188-43-23-28-100(188)116(153)209/h30-33,54,64-75,79-101,110-115,190-199H,18-29,34-53,55-63,146-148H2,1-17H3,(H2,149,200)(H2,150,201)(H2,151,202)(H2,152,203)(H2,153,209)(H,156,161)(H,158,211)(H,159,212)(H,160,231)(H,162,204)(H,163,205)(H,164,223)(H,165,215)(H,166,219)(H,167,226)(H,168,230)(H,169,213)(H,170,214)(H,171,216)(H,172,224)(H,173,220)(H,174,227)(H,175,232)(H,176,233)(H,177,234)(H,178,210)(H,179,221)(H,180,222)(H,181,235)(H,182,206)(H,183,229)(H,184,225)(H,185,217)(H,186,218)(H,187,228)(H,207,208)(H4,154,155,157)/t71-,72-,73-,74-,75-,79+,80+,81+,82+,83+,84+,85+,86+,87+,88+,89+,90+,91+,92+,93+,94+,95+,96+,97+,98+,99+,100+,101+,110+,111+,112+,113+,114+,115+/m1/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BBBFJLBPOGFECG-VJVYQDLKSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "3431.85300" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "3429.71331" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(N)=O" xsd:string - -[Term] -id: CHEBI:33232 -name: application -namespace: chebi_ontology -def: "Intended use of the molecular entity or part thereof by humans." [] -subset: 3_STAR -is_a: BFO:0000023 ! role -is_a: CHEBI:50906 ! role - -[Term] -id: CHEBI:33233 -name: fundamental particle -namespace: chebi_ontology -def: "A particle not known to have substructure." [] -subset: 3_STAR -synonym: "elementary particle" EXACT IUPAC_NAME [IUPAC] -synonym: "elementary particles" RELATED [ChEBI] -is_a: CHEBI:36342 ! subatomic particle - -[Term] -id: CHEBI:33238 -name: monoatomic entity -namespace: chebi_ontology -def: "A monoatomic entity is a molecular entity consisting of a single atom." [] -subset: 3_STAR -synonym: "atomic entity" RELATED [ChEBI] -synonym: "monoatomic entities" RELATED [ChEBI] -is_a: CHEBI:33259 ! elemental molecular entity - -[Term] -id: CHEBI:33241 -name: oxoacid derivative -namespace: chebi_ontology -subset: 3_STAR -synonym: "oxoacid derivatives" RELATED [ChEBI] -is_a: CHEBI:37577 ! heteroatomic molecular entity -relationship: has_functional_parent CHEBI:24833 ! oxoacid - -[Term] -id: CHEBI:33242 -name: inorganic hydride -namespace: chebi_ontology -subset: 3_STAR -synonym: "inorganic hydrides" RELATED [ChEBI] -is_a: CHEBI:24835 ! inorganic molecular entity -is_a: CHEBI:33692 ! hydrides - -[Term] -id: CHEBI:33245 -name: organic fundamental parent -namespace: chebi_ontology -def: "An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system." [] -subset: 3_STAR -synonym: "organic fundamental parents" RELATED [ChEBI] -synonym: "organic parent hydrides" RELATED [ChEBI] -is_a: CHEBI:37175 ! organic hydride -is_a: CHEBI:50860 ! organic molecular entity - -[Term] -id: CHEBI:33246 -name: inorganic group -namespace: chebi_ontology -def: "Any substituent group which does not contain carbon." [] -subset: 3_STAR -synonym: "inorganic groups" RELATED [ChEBI] -is_a: CHEBI:24433 ! group - -[Term] -id: CHEBI:33247 -name: organic group -namespace: chebi_ontology -def: "Any substituent group or skeleton containing carbon." [] -subset: 3_STAR -synonym: "organic groups" RELATED [ChEBI] -is_a: CHEBI:24433 ! group -relationship: is_substituent_group_from CHEBI:50860 ! organic molecular entity - -[Term] -id: CHEBI:33249 -name: organyl group -namespace: chebi_ontology -def: "Any organic substituent group, regardless of functional type, having one free valence at a carbon atom." [] -subset: 3_STAR -synonym: "groupe organyle" RELATED [IUPAC] -synonym: "grupo organilo" RELATED [IUPAC] -synonym: "grupos organilo" RELATED [IUPAC] -synonym: "organyl group" EXACT IUPAC_NAME [IUPAC] -synonym: "organyl groups" EXACT IUPAC_NAME [IUPAC] -is_a: CHEBI:51447 ! organic univalent group - -[Term] -id: CHEBI:33250 -name: atom -namespace: chebi_ontology -alt_id: CHEBI:22671 -alt_id: CHEBI:23907 -def: "A chemical entity constituting the smallest component of an element having the chemical properties of the element." [] -subset: 3_STAR -synonym: "atom" EXACT IUPAC_NAME [IUPAC] -synonym: "atome" RELATED [IUPAC] -synonym: "atomo" RELATED [IUPAC] -synonym: "atoms" RELATED [ChEBI] -synonym: "atomus" RELATED [ChEBI] -synonym: "element" RELATED [ChEBI] -synonym: "elements" RELATED [ChEBI] -is_a: CHEBI:24431 ! chemical entity -relationship: has_part CHEBI:10545 ! electron -relationship: has_part CHEBI:33252 ! atomic nucleus - -[Term] -id: CHEBI:33252 -name: atomic nucleus -namespace: chebi_ontology -def: "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons." [] -subset: 3_STAR -synonym: "Atomkern" RELATED [ChEBI] -synonym: "Kern" RELATED [ChEBI] -synonym: "noyau" RELATED [IUPAC] -synonym: "noyau atomique" RELATED [ChEBI] -synonym: "nuclei" RELATED [ChEBI] -synonym: "nucleo" RELATED [IUPAC] -synonym: "nucleo atomico" RELATED [ChEBI] -synonym: "nucleus" EXACT IUPAC_NAME [IUPAC] -synonym: "nucleus atomi" RELATED [ChEBI] -is_a: CHEBI:36347 ! nuclear particle -relationship: has_part CHEBI:33253 ! nucleon - -[Term] -id: CHEBI:33253 -name: nucleon -namespace: chebi_ontology -def: "Heavy nuclear particle: proton or neutron." [] -subset: 3_STAR -synonym: "nucleon" EXACT [IUPAC] -synonym: "nucleon" EXACT IUPAC_NAME [IUPAC] -synonym: "nucleons" RELATED [ChEBI] -synonym: "Nukleon" RELATED [ChEBI] -synonym: "Nukleonen" RELATED [ChEBI] -is_a: CHEBI:36339 ! baryon -is_a: CHEBI:36347 ! nuclear particle - -[Term] -id: CHEBI:33256 -name: primary amide -namespace: chebi_ontology -def: "A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [ANON:ANON] -subset: 3_STAR -synonym: "primary amide" EXACT [IUPAC:] -synonym: "primary amide" EXACT [IUPAC] -synonym: "primary amides" EXACT IUPAC_NAME [IUPAC] -synonym: "primary amides" EXACT IUPAC_NAME [IUPAC:] -is_a: CHEBI:32988 ! amide - -[Term] -id: CHEBI:33259 -name: elemental molecular entity -namespace: chebi_ontology -def: "A molecular entity all atoms of which have the same atomic number." [] -subset: 3_STAR -synonym: "homoatomic entity" RELATED [ChEBI] -synonym: "homoatomic molecular entities" RELATED [ChEBI] -synonym: "homoatomic molecular entity" RELATED [ChEBI] -is_a: CHEBI:23367 ! molecular entity - -[Term] -id: CHEBI:33262 -name: elemental oxygen -namespace: chebi_ontology -subset: 3_STAR -is_a: CHEBI:24835 ! inorganic molecular entity -is_a: CHEBI:25806 ! oxygen molecular entity -is_a: CHEBI:33259 ! elemental molecular entity - -[Term] -id: CHEBI:33263 -name: diatomic oxygen -namespace: chebi_ontology -subset: 3_STAR -is_a: CHEBI:33262 ! elemental oxygen -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "O2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "31.999" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "31.98983" xsd:string - -[Term] -id: CHEBI:33273 -name: polyatomic anion -namespace: chebi_ontology -def: "An anion consisting of more than one atom." [] -subset: 3_STAR -synonym: "polyatomic anions" RELATED [ChEBI] -is_a: CHEBI:22563 ! anion -is_a: CHEBI:36358 ! polyatomic ion - -[Term] -id: CHEBI:33280 -name: molecular messenger -namespace: chebi_ontology -subset: 3_STAR -synonym: "chemical messenger" RELATED [ChEBI] -is_a: CHEBI:24432 ! biological role - -[Term] -id: CHEBI:33281 -name: antimicrobial agent -namespace: chebi_ontology -alt_id: CHEBI:22582 -def: "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans." [] -subset: 3_STAR -synonym: "antibiotic" RELATED [ChEBI] -synonym: "antibiotics" RELATED [ChEBI] -synonym: "Antibiotika" RELATED [ChEBI] -synonym: "Antibiotikum" RELATED [ChEBI] -synonym: "antibiotique" RELATED [IUPAC] -synonym: "antimicrobial" RELATED [ChEBI] -synonym: "antimicrobial agents" RELATED [ChEBI] -synonym: "antimicrobials" RELATED [ChEBI] -synonym: "microbicide" RELATED [ChEBI] -synonym: "microbicides" RELATED [ChEBI] -xref: PMID:12964249 {source="Europe PMC"} -xref: PMID:22117953 {source="Europe PMC"} -xref: PMID:22439833 {source="Europe PMC"} -xref: PMID:22849268 {source="Europe PMC"} -xref: PMID:22849276 {source="Europe PMC"} -xref: PMID:22958833 {source="Europe PMC"} -is_a: CHEBI:24432 ! biological role - -[Term] -id: CHEBI:33282 -name: antibacterial agent -namespace: chebi_ontology -def: "A substance (or active part thereof) that kills or slows the growth of bacteria." [] -subset: 3_STAR -synonym: "antibacterial agents" RELATED [ChEBI] -synonym: "antibacterials" RELATED [ChEBI] -synonym: "bactericide" RELATED [ChEBI] -synonym: "bactericides" RELATED [ChEBI] -is_a: CHEBI:33281 ! antimicrobial agent - -[Term] -id: CHEBI:33284 -name: nutrient -namespace: chebi_ontology -def: "A nutrient is a food component that an organism uses to survive and grow." [] -subset: 3_STAR -synonym: "nutrients" RELATED [ChEBI] -is_a: CHEBI:78295 ! food component - -[Term] -id: CHEBI:33285 -name: heteroorganic entity -namespace: chebi_ontology -def: "A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms." [ANON:ANON] -subset: 3_STAR -synonym: "heteroorganic entities" RELATED [ChEBI:] -synonym: "heteroorganic entities" RELATED [ChEBI] -synonym: "organoelement compounds" RELATED [ChEBI:] -synonym: "organoelement compounds" RELATED [ChEBI] -is_a: CHEBI:50860 ! organic molecular entity - -[Term] -id: CHEBI:33286 -name: agrochemical -namespace: chebi_ontology -def: "An agrochemical is a substance that is used in agriculture or horticulture." [] -subset: 3_STAR -synonym: "agrichemical" RELATED [ChEBI] -synonym: "agrichemicals" RELATED [ChEBI] -synonym: "agricultural chemicals" RELATED [ChEBI] -synonym: "agrochemicals" RELATED [ChEBI] -xref: Wikipedia:Agrochemical -is_a: CHEBI:33232 ! application - -[Term] -id: CHEBI:33287 -name: fertilizer -namespace: chebi_ontology -def: "A fertilizer is any substance that is added to soil or water to assist the growth of plants." [] -subset: 3_STAR -synonym: "fertiliser" RELATED [ChEBI] -synonym: "fertilizers" RELATED [ChEBI] -is_a: CHEBI:33286 ! agrochemical - -[Term] -id: CHEBI:33295 -name: diagnostic agent -namespace: chebi_ontology -def: "A substance administered to aid diagnosis of a disease." [] -subset: 3_STAR -synonym: "diagnostic aid" RELATED [ChEBI] -is_a: CHEBI:52217 ! pharmaceutical - -[Term] -id: CHEBI:33296 -name: alkali metal molecular entity -namespace: chebi_ontology -def: "A molecular entity containing one or more atoms of an alkali metal." [] -subset: 3_STAR -synonym: "alkali metal molecular entities" RELATED [ChEBI] -is_a: CHEBI:33674 ! s-block molecular entity -relationship: has_part CHEBI:22314 ! alkali metal atom - -[Term] -id: CHEBI:33299 -name: alkaline earth molecular entity -namespace: chebi_ontology -def: "An alkaline earth molecular entity is a molecular entity containing one or more atoms of an alkaline earth metal." [] -subset: 3_STAR -synonym: "alkaline earth compounds" RELATED [ChEBI] -synonym: "alkaline earth molecular entities" RELATED [ChEBI] -synonym: "alkaline earth molecular entity" EXACT [ChEBI] -synonym: "alkaline-earth compounds" RELATED [ChEBI] -is_a: CHEBI:33674 ! s-block molecular entity -relationship: has_part CHEBI:22313 ! alkaline earth metal atom - -[Term] -id: CHEBI:33300 -name: pnictogen -namespace: chebi_ontology -def: "Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth." [] -subset: 3_STAR -synonym: "group 15 elements" RELATED [ChEBI] -synonym: "group V elements" RELATED [ChEBI] -synonym: "nitrogenoideos" RELATED [ChEBI] -synonym: "nitrogenoides" RELATED [ChEBI] -synonym: "pnictogene" RELATED [ChEBI] -synonym: "pnictogenes" RELATED [ChEBI] -synonym: "pnictogens" EXACT IUPAC_NAME [IUPAC] -is_a: CHEBI:33560 ! p-block element atom - -[Term] -id: CHEBI:33302 -name: pnictogen molecular entity -namespace: chebi_ontology -def: "A p-block molecular entity containing any pnictogen." [] -subset: 3_STAR -synonym: "pnictogen molecular entities" RELATED [ChEBI:] -synonym: "pnictogen molecular entities" RELATED [ChEBI] -synonym: "pnictogen molecular entity" EXACT [ChEBI] -synonym: "pnictogen molecular entity" EXACT [ChEBI:] -is_a: CHEBI:33675 ! p-block molecular entity -relationship: has_part CHEBI:33300 ! pnictogen - -[Term] -id: CHEBI:33303 -name: chalcogen -namespace: chebi_ontology -def: "Any p-block element belonging to the group 16 family of the periodic table." [] -subset: 3_STAR -synonym: "anfigeno" RELATED [ChEBI] -synonym: "anfigenos" RELATED [ChEBI] -synonym: "calcogeno" RELATED [ChEBI] -synonym: "calcogenos" RELATED [ChEBI] -synonym: "chalcogen" EXACT IUPAC_NAME [IUPAC] -synonym: "chalcogene" RELATED [ChEBI] -synonym: "chalcogenes" RELATED [ChEBI] -synonym: "chalcogens" EXACT IUPAC_NAME [IUPAC] -synonym: "Chalkogen" RELATED [ChEBI] -synonym: "Chalkogene" RELATED [ChEBI] -synonym: "group 16 elements" RELATED [ChEBI] -synonym: "group VI elements" RELATED [ChEBI] -xref: PMID:17084588 {source="Europe PMC"} -is_a: CHEBI:33560 ! p-block element atom - -[Term] -id: CHEBI:33304 -name: chalcogen molecular entity -namespace: chebi_ontology -def: "Any p-block molecular entity containing a chalcogen." [ANON:ANON] -subset: 3_STAR -synonym: "chalcogen compounds" RELATED [ChEBI:] -synonym: "chalcogen compounds" RELATED [ChEBI] -synonym: "chalcogen molecular entities" RELATED [ChEBI:] -synonym: "chalcogen molecular entities" RELATED [ChEBI] -synonym: "chalcogen molecular entity" EXACT [ChEBI] -synonym: "chalcogen molecular entity" EXACT [ChEBI:] -is_a: CHEBI:33675 ! p-block molecular entity -relationship: has_part CHEBI:33303 ! chalcogen - -[Term] -id: CHEBI:33306 -name: carbon group element atom -namespace: chebi_ontology -subset: 3_STAR -synonym: "carbon group element" RELATED [ChEBI] -synonym: "carbon group elements" RELATED [ChEBI] -synonym: "carbonoides" RELATED [ChEBI] -synonym: "cristallogene" RELATED [ChEBI] -synonym: "cristallogenes" RELATED [ChEBI] -synonym: "group 14 elements" EXACT IUPAC_NAME [IUPAC] -synonym: "group IV elements" RELATED [ChEBI] -is_a: CHEBI:33560 ! p-block element atom - -[Term] -id: CHEBI:33308 -name: carboxylic ester -namespace: chebi_ontology -alt_id: CHEBI:13204 -alt_id: CHEBI:23028 -alt_id: CHEBI:3408 -def: "An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl." [] -def: "An ester of a carboxylic acid." [ANON:ANON] -subset: 3_STAR -synonym: "a carboxylic ester" RELATED [UniProt] -synonym: "carboxylic acid esters" RELATED [ChEBI] -synonym: "carboxylic acid esters" RELATED [ChEBI:] -synonym: "Carboxylic ester" EXACT [KEGG_COMPOUND] -synonym: "Carboxylic ester" EXACT [KEGG COMPOUND:] -synonym: "carboxylic ester" EXACT [UniProt:] -synonym: "carboxylic esters" EXACT IUPAC_NAME [IUPAC:] -synonym: "carboxylic esters" EXACT IUPAC_NAME [IUPAC] -synonym: "CO2R2" RELATED FORMULA [KEGG COMPOUND:] -xref: KEGG:C02391 -xref: Wikipedia:Ester -is_a: CHEBI:35701 ! ester -is_a: CHEBI:36586 ! carbonyl compound -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "44.010" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]C(=O)O[*]" xsd:string - -[Term] -id: CHEBI:33318 -name: main group element atom -namespace: chebi_ontology -def: "An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table." [] -subset: 3_STAR -synonym: "Hauptgruppenelement" RELATED [ChEBI] -synonym: "Hauptgruppenelemente" RELATED [ChEBI] -synonym: "main group element" RELATED [ChEBI] -synonym: "main group elements" EXACT IUPAC_NAME [IUPAC] -is_a: CHEBI:33250 ! atom - -[Term] -id: CHEBI:33356 -name: iron group element atom -namespace: chebi_ontology -subset: 3_STAR -synonym: "group 8 elements" EXACT IUPAC_NAME [IUPAC] -synonym: "iron group element" RELATED [ChEBI] -synonym: "iron group elements" RELATED [ChEBI] -is_a: CHEBI:33561 ! d-block element atom - -[Term] -id: CHEBI:33402 -name: sulfur oxoacid -namespace: chebi_ontology -subset: 3_STAR -synonym: "oxoacids of sulfur" RELATED [ChEBI] -synonym: "sulfur oxoacids" RELATED [ChEBI] -is_a: CHEBI:26835 ! sulfur molecular entity -is_a: CHEBI:33484 ! chalcogen oxoacid - -[Term] -id: CHEBI:33408 -name: pnictogen oxoacid -namespace: chebi_ontology -subset: 3_STAR -synonym: "pnictogen oxoacids" RELATED [ChEBI] -is_a: CHEBI:24833 ! oxoacid -is_a: CHEBI:33302 ! pnictogen molecular entity -relationship: RO:0000087 CHEBI:138103 ! has role inorganic acid - -[Term] -id: CHEBI:33424 -name: sulfur oxoacid derivative -namespace: chebi_ontology -subset: 3_STAR -synonym: "sulfur oxoacid derivative" EXACT [ChEBI] -synonym: "sulfur oxoacid derivatives" RELATED [ChEBI] -is_a: CHEBI:26835 ! sulfur molecular entity -is_a: CHEBI:33241 ! oxoacid derivative - -[Term] -id: CHEBI:33457 -name: phosphorus oxoacid -namespace: chebi_ontology -def: "A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons." [] -subset: 3_STAR -synonym: "oxoacids of phosphorus" RELATED [ChEBI] -synonym: "Oxosaeure des Phosphors" RELATED [ChEBI] -synonym: "phosphorus oxoacid" EXACT [ChEBI] -synonym: "phosphorus oxoacids" RELATED [ChEBI] -is_a: CHEBI:33408 ! pnictogen oxoacid -is_a: CHEBI:36360 ! phosphorus oxoacids and derivatives - -[Term] -id: CHEBI:33459 -name: pnictogen oxoanion -namespace: chebi_ontology -subset: 3_STAR -synonym: "pnictogen oxoanion" EXACT [ChEBI] -synonym: "pnictogen oxoanions" RELATED [ChEBI] -is_a: CHEBI:33302 ! pnictogen molecular entity -is_a: CHEBI:35406 ! oxoanion - -[Term] -id: CHEBI:33461 -name: phosphorus oxoanion -namespace: chebi_ontology -subset: 3_STAR -synonym: "oxoanions of phosphorus" RELATED [ChEBI] -synonym: "phosphorus oxoanion" EXACT [ChEBI] -synonym: "phosphorus oxoanions" RELATED [ChEBI] -is_a: CHEBI:24834 ! inorganic anion -is_a: CHEBI:26082 ! phosphorus molecular entity -is_a: CHEBI:33459 ! pnictogen oxoanion - -[Term] -id: CHEBI:33482 -name: sulfur oxoanion -namespace: chebi_ontology -subset: 3_STAR -synonym: "oxoanions of sulfur" RELATED [ChEBI] -synonym: "sulfur oxoanion" EXACT [ChEBI] -synonym: "sulfur oxoanions" RELATED [ChEBI] -is_a: CHEBI:26835 ! sulfur molecular entity -is_a: CHEBI:33485 ! chalcogen oxoanion - -[Term] -id: CHEBI:33484 -name: chalcogen oxoacid -namespace: chebi_ontology -subset: 3_STAR -synonym: "chalcogen oxoacid" EXACT [ChEBI] -synonym: "chalcogen oxoacids" RELATED [ChEBI] -is_a: CHEBI:24833 ! oxoacid -relationship: RO:0000087 CHEBI:138103 ! has role inorganic acid - -[Term] -id: CHEBI:33485 -name: chalcogen oxoanion -namespace: chebi_ontology -subset: 3_STAR -synonym: "chalcogen oxoanion" EXACT [ChEBI] -synonym: "chalcogen oxoanions" RELATED [ChEBI] -is_a: CHEBI:35406 ! oxoanion - -[Term] -id: CHEBI:33497 -name: transition element molecular entity -namespace: chebi_ontology -def: "A molecular entity containing one or more atoms of a transition element." [] -subset: 3_STAR -synonym: "transition element molecular entities" RELATED [ChEBI] -synonym: "transition metal molecular entity" RELATED [ChEBI] -is_a: CHEBI:23367 ! molecular entity -relationship: has_part CHEBI:27081 ! transition element atom - -[Term] -id: CHEBI:33504 -name: alkali metal cation -namespace: chebi_ontology -subset: 3_STAR -synonym: "alkali metal cations" RELATED [ChEBI] -is_a: CHEBI:25213 ! metal cation - -[Term] -id: CHEBI:33513 -name: alkaline earth cation -namespace: chebi_ontology -subset: 3_STAR -synonym: "alkaline earth cations" RELATED [ChEBI] -synonym: "alkaline earth metal cation" RELATED [ChEBI] -synonym: "alkaline-earth metal cations" RELATED [ChEBI] -is_a: CHEBI:25213 ! metal cation -is_a: CHEBI:33299 ! alkaline earth molecular entity - -[Term] -id: CHEBI:33515 -name: transition element cation -namespace: chebi_ontology -subset: 3_STAR -synonym: "transition element cations" RELATED [ChEBI] -synonym: "transition metal cation" RELATED [ChEBI] -is_a: CHEBI:25213 ! metal cation - -[Term] -id: CHEBI:33521 -name: metal atom -namespace: chebi_ontology -alt_id: CHEBI:25217 -alt_id: CHEBI:6788 -def: "An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity." [] -subset: 3_STAR -synonym: "elemental metal" RELATED [ChEBI] -synonym: "elemental metals" RELATED [ChEBI] -synonym: "metal element" RELATED [ChEBI] -synonym: "metal elements" RELATED [ChEBI] -synonym: "metals" RELATED [ChEBI] -xref: KEGG:C00050 -xref: PMID:21784043 {source="Europe PMC"} -xref: Wikipedia:Metal -is_a: CHEBI:33250 ! atom - -[Term] -id: CHEBI:33558 -name: alpha-amino-acid anion -namespace: chebi_ontology -def: "An amino-acid anion obtained by deprotonation of any alpha-amino acid." [] -subset: 3_STAR -synonym: "alpha-amino acid anions" RELATED [ChEBI] -synonym: "alpha-amino-acid anion" EXACT [ChEBI] -synonym: "alpha-amino-acid anions" RELATED [ChEBI] -is_a: CHEBI:37022 ! amino-acid anion -relationship: is_conjugate_base_of CHEBI:33704 ! alpha-amino acid - -[Term] -id: CHEBI:33559 -name: s-block element atom -namespace: chebi_ontology -subset: 3_STAR -synonym: "s-block element" RELATED [ChEBI] -synonym: "s-block elements" RELATED [ChEBI] -is_a: CHEBI:33250 ! atom - -[Term] -id: CHEBI:33560 -name: p-block element atom -namespace: chebi_ontology -def: "Any main group element atom belonging to the p-block of the periodic table." [] -subset: 3_STAR -synonym: "p-block element" RELATED [ChEBI] -synonym: "p-block elements" RELATED [ChEBI] -is_a: CHEBI:33318 ! main group element atom - -[Term] -id: CHEBI:33561 -name: d-block element atom -namespace: chebi_ontology -subset: 3_STAR -synonym: "d-block element" RELATED [ChEBI] -synonym: "d-block elements" RELATED [ChEBI] -is_a: CHEBI:27081 ! transition element atom - -[Term] -id: CHEBI:33563 -name: glycolipid -namespace: chebi_ontology -alt_id: CHEBI:24393 -alt_id: CHEBI:5476 -def: "Any member of class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar part acylated by one or more fatty acids and the glycerol part may be absent." [] -subset: 3_STAR -synonym: "Glycolipid" EXACT [KEGG_COMPOUND] -synonym: "glycolipids" EXACT IUPAC_NAME [IUPAC] -xref: KEGG:C05005 -xref: Wikipedia:Glycolipids -is_a: CHEBI:35740 ! liposaccharide [Term] id: CHEBI:33566 -name: catechols namespace: chebi_ontology -alt_id: CHEBI:134187 -alt_id: CHEBI:13628 -alt_id: CHEBI:18862 -def: "Any compound containing an o-diphenol component." [] -subset: 3_STAR -synonym: "1,2-benzenediols" RELATED [ChEBI] -synonym: "a catechol" RELATED [UniProt] -synonym: "benzene-1,2-diols" RELATED [ChEBI] -xref: KEGG:C15571 -is_a: CHEBI:33570 ! benzenediols -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H2O2R4" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "106.079" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "106.00548" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC1=C(O)C(*)=C(*)C(*)=C1*" xsd:string [Term] id: CHEBI:33567 -name: catecholamine namespace: chebi_ontology -alt_id: CHEBI:23056 -alt_id: CHEBI:3468 def: "4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." [ANON:ANON] -subset: 3_STAR synonym: "C8H9NO2R2" RELATED FORMULA [KEGG COMPOUND:] -synonym: "Catecholamine" EXACT [KEGG_COMPOUND] synonym: "Catecholamine" EXACT [KEGG COMPOUND:] -synonym: "catecholamines" EXACT IUPAC_NAME [IUPAC] synonym: "catecholamines" EXACT IUPAC_NAME [IUPAC:] -synonym: "catecholamines" RELATED [ChEBI] synonym: "catecholamines" RELATED [ChEBI:] -xref: KEGG:C02012 -is_a: CHEBI:25375 ! monoamine molecular messenger -is_a: CHEBI:33566 ! catechols -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H9NO2R2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "151.163" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "151.06333" xsd:string - -[Term] -id: CHEBI:33568 -name: adrenaline -namespace: chebi_ontology -def: "A catecholamine in which the aminoethyl side-chain is hydroxy-substituted at C-1 and methylated on nitrogen." [] -subset: 3_STAR -synonym: "(+-)-adrenaline" RELATED [IUPHAR] -synonym: "(+-)-epinephrine" RELATED [ChemIDplus] -synonym: "2-(methylamino)-1-(3,4-dihydroxyphenyl)ethanol" RELATED [ChemIDplus] -synonym: "4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC] -synonym: "dl-adrenaline" RELATED [ChemIDplus] -synonym: "epinephrine racemic" RELATED [ChemIDplus] -synonym: "racepinefrina" RELATED INN [ChemIDplus] -synonym: "racepinefrine" RELATED INN [ChemIDplus] -synonym: "racepinefrinum" RELATED INN [ChemIDplus] -xref: Beilstein:2212160 {source="ChemIDplus"} -xref: CAS:329-65-7 {source="ChemIDplus"} -xref: Drug_Central:4508 {source="DrugCentral"} -xref: Gmelin:51559 {source="Gmelin"} -xref: LINCS:LSM-4958 -xref: PMID:10052027 {source="Europe PMC"} -xref: PMID:24252294 {source="Europe PMC"} -xref: PMID:24719616 {source="Europe PMC"} -xref: Reaxys:2212160 {source="Reaxys"} -is_a: CHEBI:33567 ! catecholamine -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C9H13NO3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "UCTWMZQNUQWSLP-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "183.20446" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "183.08954" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "CNCC(O)c1ccc(O)c(O)c1" xsd:string - -[Term] -id: CHEBI:33569 -name: noradrenaline -namespace: chebi_ontology -def: "A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted." [] -subset: 3_STAR -synonym: "4-(2-amino-1-hydroxyethyl)benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC] -synonym: "noradrenalina" RELATED [ChEBI] -synonym: "norepinephrine" RELATED [ChEBI] -xref: Beilstein:2210994 {source="Beilstein"} -xref: CAS:138-65-8 {source="NIST Chemistry WebBook"} -xref: CAS:138-65-8 {source="ChemIDplus"} -xref: Gmelin:863925 {source="Gmelin"} -xref: LINCS:LSM-5181 -is_a: CHEBI:33567 ! catecholamine -relationship: is_conjugate_base_of CHEBI:166902 ! noradrenaline(1+) -relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H11NO3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "169.17788" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "169.07389" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "NCC(O)c1ccc(O)c(O)c1" xsd:string - -[Term] -id: CHEBI:33570 -name: benzenediols -namespace: chebi_ontology -alt_id: CHEBI:22705 -alt_id: CHEBI:22711 -subset: 3_STAR -is_a: CHEBI:33853 ! phenols - -[Term] -id: CHEBI:33571 -name: (S)-noradrenaline -namespace: chebi_ontology -def: "The S-enantiomer of noradrenaline." [] -subset: 3_STAR -synonym: "4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC] -xref: Beilstein:2937999 {source="Beilstein"} -xref: LINCS:LSM-37072 -xref: Reaxys:2937999 {source="Reaxys"} -is_a: CHEBI:33569 ! noradrenaline -relationship: is_enantiomer_of CHEBI:18357 ! (R)-noradrenaline -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H11NO3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m1/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-MRVPVSSYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "169.17788" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "169.07389" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC[C@@H](O)c1ccc(O)c(O)c1" xsd:string - -[Term] -id: CHEBI:33575 -name: carboxylic acid -namespace: chebi_ontology -alt_id: CHEBI:13428 -alt_id: CHEBI:13627 -alt_id: CHEBI:23027 -def: "A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid." [] -def: "An oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid." [ANON:ANON] -subset: 3_STAR -synonym: "acide carboxylique" RELATED [IUPAC] -synonym: "acide carboxylique" RELATED [IUPAC:] -synonym: "acides carboxyliques" RELATED [IUPAC] -synonym: "acides carboxyliques" RELATED [IUPAC:] -synonym: "acido carboxilico" RELATED [IUPAC:] -synonym: "acido carboxilico" RELATED [IUPAC] -synonym: "acidos carboxilicos" RELATED [IUPAC] -synonym: "acidos carboxilicos" RELATED [IUPAC:] -synonym: "Carbonsaeure" RELATED [ChEBI] -synonym: "Carbonsaeure" RELATED [ChEBI:] -synonym: "Carbonsaeuren" RELATED [ChEBI:] -synonym: "Carbonsaeuren" RELATED [ChEBI] -synonym: "carboxylic acid" EXACT IUPAC_NAME [IUPAC:] -synonym: "carboxylic acid" EXACT IUPAC_NAME [IUPAC] -synonym: "carboxylic acids" EXACT IUPAC_NAME [IUPAC:] -synonym: "carboxylic acids" EXACT IUPAC_NAME [IUPAC] -synonym: "CHO2R" RELATED FORMULA [ChEBI:] -synonym: "Karbonsaeure" RELATED [ChEBI] -synonym: "Karbonsaeure" RELATED [ChEBI:] -synonym: "OC([*])=O" RELATED SMILES [ChEBI:] -synonym: "RC(=O)OH" RELATED [IUPAC] -synonym: "RC(=O)OH" RELATED [IUPAC:] -xref: PMID:17147560 {source="Europe PMC"} -xref: PMID:18433345 {source="Europe PMC"} -xref: Wikipedia:Carboxylic_acid -is_a: CHEBI:35605 ! carbon oxoacid -is_a: CHEBI:36586 ! carbonyl compound -is_a: CHEBI:64709 ! organic acid -relationship: has_part CHEBI:46883 ! carboxy group -relationship: is_conjugate_acid_of CHEBI:29067 ! carboxylic acid anion -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO2R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "45.01740" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.99765" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC([*])=O" xsd:string - -[Term] -id: CHEBI:33579 -name: main group molecular entity -namespace: chebi_ontology -def: "A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table." [ANON:ANON] -subset: 3_STAR -synonym: "main group compounds" RELATED [ChEBI:] -synonym: "main group compounds" RELATED [ChEBI] -synonym: "main group molecular entities" RELATED [ChEBI:] -synonym: "main group molecular entities" RELATED [ChEBI] -is_a: CHEBI:23367 ! molecular entity -relationship: has_part CHEBI:33318 ! main group element atom - -[Term] -id: CHEBI:33582 -name: carbon group molecular entity -namespace: chebi_ontology -subset: 3_STAR -synonym: "carbon group molecular entities" RELATED [ChEBI:] -synonym: "carbon group molecular entities" RELATED [ChEBI] -synonym: "carbon group molecular entity" EXACT [ChEBI] -synonym: "carbon group molecular entity" EXACT [ChEBI:] -is_a: CHEBI:33675 ! p-block molecular entity -relationship: has_part CHEBI:33306 ! carbon group element atom - -[Term] -id: CHEBI:33595 -name: cyclic compound -namespace: chebi_ontology -def: "Any molecule that consists of a series of atoms joined together to form a ring." [] -subset: 3_STAR -synonym: "cyclic compounds" RELATED [ChEBI] -synonym: "cyclic compounds" RELATED [ChEBI:] -xref: Wikipedia:Cyclic_compound -is_a: CHEBI:25367 ! molecule - -[Term] -id: CHEBI:33608 -name: hydrogen molecular entity -namespace: chebi_ontology -subset: 3_STAR -synonym: "hydrogen compounds" RELATED [ChEBI:] -synonym: "hydrogen compounds" RELATED [ChEBI] -synonym: "hydrogen molecular entities" RELATED [ChEBI] -synonym: "hydrogen molecular entities" RELATED [ChEBI:] -is_a: CHEBI:33674 ! s-block molecular entity -relationship: has_part CHEBI:49637 ! hydrogen atom - -[Term] -id: CHEBI:33635 -name: polycyclic compound -namespace: chebi_ontology -subset: 3_STAR -synonym: "polycyclic compounds" RELATED [ChEBI] -is_a: CHEBI:33595 ! cyclic compound - -[Term] -id: CHEBI:33636 -name: bicyclic compound -namespace: chebi_ontology -def: "A molecule that features two fused rings." [ANON:ANON] -subset: 3_STAR -synonym: "bicyclic compounds" RELATED [ChEBI] -synonym: "bicyclic compounds" RELATED [ChEBI:] -is_a: CHEBI:33595 ! cyclic compound - -[Term] -id: CHEBI:33653 -name: aliphatic compound -namespace: chebi_ontology -def: "Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds." [] -subset: 3_STAR -synonym: "aliphatic compounds" EXACT IUPAC_NAME [IUPAC] -is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33655 -name: aromatic compound namespace: chebi_ontology def: "A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character." [ANON:ANON] -subset: 3_STAR synonym: "aromatic compounds" EXACT IUPAC_NAME [IUPAC:] -synonym: "aromatic compounds" EXACT IUPAC_NAME [IUPAC] -synonym: "aromatic molecular entity" EXACT IUPAC_NAME [IUPAC] synonym: "aromatic molecular entity" EXACT IUPAC_NAME [IUPAC:] -synonym: "aromatics" RELATED [ChEBI] synonym: "aromatics" RELATED [ChEBI:] synonym: "aromatische Verbindungen" RELATED [ChEBI:] -synonym: "aromatische Verbindungen" RELATED [ChEBI] -is_a: CHEBI:33595 ! cyclic compound - -[Term] -id: CHEBI:33659 -name: organic aromatic compound -namespace: chebi_ontology -subset: 3_STAR -synonym: "organic aromatic compounds" RELATED [ChEBI] -synonym: "organic aromatic compounds" RELATED [ChEBI:] -is_a: CHEBI:33655 ! aromatic compound -is_a: CHEBI:33832 ! organic cyclic compound - -[Term] -id: CHEBI:33671 -name: heteropolycyclic compound -namespace: chebi_ontology -def: "A polycyclic compound in which at least one of the rings contains at least one non-carbon atom." [] -subset: 3_STAR -synonym: "heteropolycyclic compounds" EXACT IUPAC_NAME [IUPAC] -synonym: "polyheterocyclic compounds" RELATED [ChEBI] -is_a: CHEBI:33635 ! polycyclic compound -is_a: CHEBI:5686 ! heterocyclic compound - -[Term] -id: CHEBI:33672 -name: heterobicyclic compound -namespace: chebi_ontology -def: "A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom." [ANON:ANON] -subset: 3_STAR -synonym: "heterobicyclic compounds" EXACT IUPAC_NAME [IUPAC:] -synonym: "heterobicyclic compounds" EXACT IUPAC_NAME [IUPAC] -is_a: CHEBI:33636 ! bicyclic compound -is_a: CHEBI:5686 ! heterocyclic compound - -[Term] -id: CHEBI:33674 -name: s-block molecular entity -namespace: chebi_ontology -def: "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element." [ANON:ANON] -subset: 3_STAR -synonym: "s-block compounds" RELATED [ChEBI] -synonym: "s-block compounds" RELATED [ChEBI:] -synonym: "s-block molecular entities" RELATED [ChEBI] -synonym: "s-block molecular entities" RELATED [ChEBI:] -synonym: "s-block molecular entity" EXACT [ChEBI:] -synonym: "s-block molecular entity" EXACT [ChEBI] -is_a: CHEBI:33579 ! main group molecular entity -relationship: has_part CHEBI:33559 ! s-block element atom - -[Term] -id: CHEBI:33675 -name: p-block molecular entity -namespace: chebi_ontology -def: "A main group molecular entity that contains one or more atoms of a p-block element." [] -def: "A p-block molecular entity is a molecular entity containing one or more atoms of a p-block element." [ANON:ANON] -subset: 3_STAR -synonym: "p-block compounds" RELATED [ChEBI] -synonym: "p-block compounds" RELATED [ChEBI:] -synonym: "p-block molecular entities" RELATED [ChEBI:] -synonym: "p-block molecular entities" RELATED [ChEBI] -synonym: "p-block molecular entitiy" RELATED [ChEBI] -synonym: "p-block molecular entitiy" RELATED [ChEBI:] -is_a: CHEBI:33579 ! main group molecular entity -relationship: has_part CHEBI:33560 ! p-block element atom - -[Term] -id: CHEBI:33676 -name: d-block molecular entity -namespace: chebi_ontology -def: "A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element." [] -subset: 3_STAR -synonym: "d-block compounds" RELATED [ChEBI] -synonym: "d-block molecular entities" RELATED [ChEBI] -synonym: "d-block molecular entity" EXACT [ChEBI] -is_a: CHEBI:33497 ! transition element molecular entity -relationship: has_part CHEBI:33561 ! d-block element atom - -[Term] -id: CHEBI:33692 -name: hydrides -namespace: chebi_ontology -def: "Hydrides are chemical compounds of hydrogen with other chemical elements." [] -subset: 3_STAR -is_a: CHEBI:33608 ! hydrogen molecular entity -is_a: CHEBI:37577 ! heteroatomic molecular entity - -[Term] -id: CHEBI:33693 -name: oxygen hydride -namespace: chebi_ontology -subset: 3_STAR -synonym: "hydrides of oxygen" RELATED [ChEBI] -synonym: "oxygen hydride" EXACT [ChEBI] -synonym: "oxygen hydrides" RELATED [ChEBI] -is_a: CHEBI:36902 ! chalcogen hydride - -[Term] -id: CHEBI:33694 -name: biomacromolecule -namespace: chebi_ontology -def: "A macromolecule formed by a living organism." [] -subset: 3_STAR -synonym: "biomacromolecules" RELATED [ChEBI] -synonym: "biopolymer" EXACT IUPAC_NAME [IUPAC] -synonym: "Biopolymere" RELATED [ChEBI] -synonym: "biopolymers" RELATED [ChEBI] -is_a: CHEBI:33839 ! macromolecule -is_a: CHEBI:50860 ! organic molecular entity - -[Term] -id: CHEBI:33695 -name: information biomacromolecule -namespace: chebi_ontology -subset: 3_STAR -synonym: "genetically encoded biomacromolecules" RELATED [ChEBI] -synonym: "genetically encoded biopolymers" RELATED [ChEBI] -synonym: "information biomacromolecules" RELATED [ChEBI] -synonym: "information biopolymers" RELATED [ChEBI] -synonym: "information macromolecule" RELATED [ChEBI] -synonym: "information macromolecules" RELATED [ChEBI] -is_a: CHEBI:33694 ! biomacromolecule - -[Term] -id: CHEBI:33696 -name: nucleic acid -namespace: chebi_ontology -def: "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." [] -subset: 3_STAR -synonym: "acide nucleique" RELATED [ChEBI] -synonym: "acides nucleiques" RELATED [ChEBI] -synonym: "acido nucleico" RELATED [ChEBI] -synonym: "acidos nucleicos" RELATED [ChEBI] -synonym: "NA" RELATED [ChEBI] -synonym: "nucleic acids" EXACT IUPAC_NAME [IUPAC] -synonym: "Nukleinsaeure" RELATED [ChEBI] -synonym: "Nukleinsaeuren" RELATED [ChEBI] -is_a: CHEBI:15986 ! polynucleotide -relationship: has_part CHEBI:33791 ! canonical nucleoside residue -relationship: has_part CHEBI:50297 ! canonical nucleotide residue - -[Term] -id: CHEBI:33697 -name: ribonucleic acid -namespace: chebi_ontology -def: "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." [] -subset: 3_STAR -synonym: "pentosenucleic acids" RELATED [ChemIDplus] -synonym: "ribonucleic acid" EXACT [IUPAC] -synonym: "ribonucleic acids" EXACT IUPAC_NAME [IUPAC] -synonym: "ribonucleic acids" RELATED [ChEBI] -synonym: "Ribonukleinsaeure" RELATED [ChEBI] -synonym: "ribose nucleic acid" RELATED [ChEBI] -synonym: "RNA" RELATED [UniProt] -synonym: "RNA" RELATED [IUPAC] -synonym: "RNS" RELATED [ChEBI] -synonym: "yeast nucleic acid" RELATED [ChEBI] -xref: CAS:63231-63-0 {source="ChemIDplus"} -is_a: CHEBI:33696 ! nucleic acid -relationship: has_part CHEBI:33792 ! canonical ribonucleoside residue -relationship: has_part CHEBI:50299 ! canonical ribonucleotide residue - -[Term] -id: CHEBI:33700 -name: proteinogenic amino-acid residue -namespace: chebi_ontology -subset: 3_STAR -synonym: "canonical amino-acid residue" RELATED [ChEBI] -synonym: "canonical amino-acid residues" RELATED [ChEBI] -synonym: "common amino acid residues" RELATED [ChEBI] -synonym: "proteinogenic amino-acid residues" RELATED [ChEBI] -synonym: "standard amino acid residues" RELATED [ChEBI] -synonym: "standard amino-acid residues" RELATED [ChEBI] -is_a: CHEBI:33710 ! alpha-amino-acid residue - -[Term] -id: CHEBI:33702 -name: polyatomic cation -namespace: chebi_ontology -def: "A cation consisting of more than one atom." [ANON:ANON] -subset: 3_STAR -synonym: "polyatomic cations" RELATED [ChEBI:] -synonym: "polyatomic cations" RELATED [ChEBI] -is_a: CHEBI:36358 ! polyatomic ion -is_a: CHEBI:36916 ! cation - -[Term] -id: CHEBI:33703 -name: amino-acid cation -namespace: chebi_ontology -subset: 3_STAR -synonym: "amino acid cation" RELATED [ChEBI] -synonym: "amino-acid cation" EXACT [ChEBI] -synonym: "amino-acid cations" RELATED [ChEBI] -is_a: CHEBI:33702 ! polyatomic cation - -[Term] -id: CHEBI:33704 -name: alpha-amino acid -namespace: chebi_ontology -alt_id: CHEBI:10208 -alt_id: CHEBI:13779 -alt_id: CHEBI:22442 -alt_id: CHEBI:2642 -def: "An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group." [] -subset: 3_STAR -synonym: "alpha-amino acid" EXACT IUPAC_NAME [IUPAC:] -synonym: "alpha-amino acid" EXACT IUPAC_NAME [IUPAC] -synonym: "alpha-amino acids" RELATED [JCBN:] -synonym: "alpha-amino acids" RELATED [ChEBI] -synonym: "alpha-amino acids" RELATED [ChEBI:] -synonym: "alpha-amino acids" RELATED [JCBN] -synonym: "alpha-amino carboxylic acids" RELATED [IUPAC:] -synonym: "alpha-amino carboxylic acids" RELATED [IUPAC] -synonym: "Amino acid" RELATED [KEGG_COMPOUND] -synonym: "Amino acid" RELATED [KEGG COMPOUND:] -synonym: "Amino acids" RELATED [KEGG_COMPOUND] -synonym: "an alpha-amino acid" RELATED [UniProt:] -xref: KEGG:C00045 -xref: KEGG:C05167 -is_a: CHEBI:33709 ! amino acid -relationship: is_conjugate_acid_of CHEBI:33558 ! alpha-amino-acid anion -relationship: is_tautomer_of CHEBI:78608 ! alpha-amino acid zwitterion -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "74.05870" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC([*])C(O)=O" xsd:string - -[Term] -id: CHEBI:33707 -name: gamma-amino acid -namespace: chebi_ontology -def: "A non-proteinogenic amino-acid in which the amino group is located on the carbon atom at the position gamma to the carboxy group." [] -subset: 3_STAR -synonym: "gamma-amino acid" EXACT [ChEBI] -synonym: "gamma-amino acid" EXACT [ChEBI:] -synonym: "gamma-amino acids" RELATED [ChEBI:] -synonym: "gamma-amino acids" RELATED [ChEBI] -is_a: CHEBI:83820 ! non-proteinogenic amino acid -relationship: is_conjugate_acid_of CHEBI:71666 ! gamma-amino acid anion - -[Term] -id: CHEBI:33708 -name: amino-acid residue -namespace: chebi_ontology -def: "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue." [] -subset: 3_STAR -synonym: "amino acid residue" RELATED [ChEBI] -synonym: "amino-acid residue" EXACT IUPAC_NAME [IUPAC] -synonym: "amino-acid residues" RELATED [JCBN] -is_a: CHEBI:33247 ! organic group -relationship: is_substituent_group_from CHEBI:33709 ! amino acid [Term] id: CHEBI:33709 -name: amino acid namespace: chebi_ontology -alt_id: CHEBI:13815 -alt_id: CHEBI:22477 def: "A carboxylic acid containing one or more amino groups." [ANON:ANON] -subset: 3_STAR -synonym: "amino acids" RELATED [ChEBI] synonym: "amino acids" RELATED [ChEBI:] synonym: "Aminocarbonsaeure" RELATED [ChEBI:] -synonym: "Aminocarbonsaeure" RELATED [ChEBI] -synonym: "Aminokarbonsaeure" RELATED [ChEBI] synonym: "Aminokarbonsaeure" RELATED [ChEBI:] -synonym: "Aminosaeure" RELATED [ChEBI] synonym: "Aminosaeure" RELATED [ChEBI:] -xref: Wikipedia:Amino_acid -is_a: CHEBI:33575 ! carboxylic acid -is_a: CHEBI:50047 ! organic amino compound -relationship: is_conjugate_acid_of CHEBI:37022 ! amino-acid anion - -[Term] -id: CHEBI:33710 -name: alpha-amino-acid residue -namespace: chebi_ontology -subset: 3_STAR -synonym: "alpha-amino-acid residues" RELATED [ChEBI] -is_a: CHEBI:33708 ! amino-acid residue -relationship: is_substituent_group_from CHEBI:33704 ! alpha-amino acid - -[Term] -id: CHEBI:33719 -name: alpha-amino-acid cation -namespace: chebi_ontology -subset: 3_STAR -synonym: "alpha-amino acid cations" RELATED [ChEBI] -synonym: "alpha-amino-acid cation" EXACT [ChEBI] -synonym: "alpha-amino-acid cations" RELATED [ChEBI] -is_a: CHEBI:33703 ! amino-acid cation - -[Term] -id: CHEBI:33720 -name: carbohydrate acid -namespace: chebi_ontology -subset: 3_STAR -synonym: "carbohydrate acid" EXACT [ChEBI] -synonym: "carbohydrate acids" RELATED [ChEBI] -is_a: CHEBI:16646 ! carbohydrate -is_a: CHEBI:33575 ! carboxylic acid -relationship: is_conjugate_acid_of CHEBI:33721 ! carbohydrate acid anion - -[Term] -id: CHEBI:33721 -name: carbohydrate acid anion -namespace: chebi_ontology -subset: 3_STAR -synonym: "carbohydrate acid anion" EXACT [ChEBI] -synonym: "carbohydrate acid anions" RELATED [ChEBI] -is_a: CHEBI:29067 ! carboxylic acid anion -relationship: is_conjugate_base_of CHEBI:33720 ! carbohydrate acid - -[Term] -id: CHEBI:33744 -name: iron group molecular entity -namespace: chebi_ontology -subset: 3_STAR -synonym: "iron group molecular entities" RELATED [ChEBI] -synonym: "iron group molecular entity" EXACT [ChEBI] -is_a: CHEBI:33676 ! d-block molecular entity -relationship: has_part CHEBI:33356 ! iron group element atom - -[Term] -id: CHEBI:33791 -name: canonical nucleoside residue -namespace: chebi_ontology -subset: 3_STAR -synonym: "canonical nucleoside residues" RELATED [ChEBI] -synonym: "common nucleoside residues" RELATED [CBN] -synonym: "nucleoside residue" RELATED [CBN] -synonym: "standard nucleoside residues" RELATED [ChEBI] -is_a: CHEBI:50320 ! nucleoside residue - -[Term] -id: CHEBI:33792 -name: canonical ribonucleoside residue -namespace: chebi_ontology -subset: 3_STAR -synonym: "canonical ribonucleoside residues" RELATED [ChEBI] -synonym: "common ribonucleoside residue" RELATED [CBN] -synonym: "common ribonucleoside residues" RELATED [CBN] -synonym: "N" RELATED [CBN] -synonym: "Nuc" RELATED [CBN] -synonym: "standard ribonucleoside residues" RELATED [ChEBI] -is_a: CHEBI:33791 ! canonical nucleoside residue - -[Term] -id: CHEBI:33793 -name: canonical deoxyribonucleoside residue -namespace: chebi_ontology -subset: 3_STAR -synonym: "canonical deoxyribonucleoside residues" RELATED [ChEBI] -synonym: "common 2'-deoxyribonucleoside residue" RELATED [CBN] -synonym: "common 2'-deoxyribonucleoside residues" RELATED [CBN] -synonym: "dN" RELATED [CBN] -synonym: "dNuc" RELATED [CBN] -synonym: "standard deoxyribonucleoside residues" RELATED [ChEBI] -is_a: CHEBI:33791 ! canonical nucleoside residue [Term] id: CHEBI:33822 -name: organic hydroxy compound namespace: chebi_ontology -alt_id: CHEBI:64710 def: "An organic compound having at least one hydroxy group attached to a carbon atom." [ANON:ANON] -subset: 3_STAR -synonym: "hydroxy compounds" EXACT IUPAC_NAME [IUPAC] synonym: "hydroxy compounds" EXACT IUPAC_NAME [IUPAC:] -synonym: "organic alcohol" RELATED [ChEBI] synonym: "organic hydroxy compounds" RELATED [ChEBI:] -synonym: "organic hydroxy compounds" RELATED [ChEBI] -is_a: CHEBI:24651 ! hydroxides -is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33832 -name: organic cyclic compound namespace: chebi_ontology -def: "Any organic molecule that consists of atoms connected in the form of a ring." [] -subset: 3_STAR synonym: "organic cyclic compounds" RELATED [ChEBI:] -synonym: "organic cyclic compounds" RELATED [ChEBI] -is_a: CHEBI:33595 ! cyclic compound -is_a: CHEBI:72695 ! organic molecule - -[Term] -id: CHEBI:33833 -name: heteroarene -namespace: chebi_ontology -def: "A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2)." [ANON:ANON] -subset: 3_STAR -synonym: "hetarenes" RELATED [IUPAC:] -synonym: "hetarenes" RELATED [IUPAC] -synonym: "heteroarenes" EXACT IUPAC_NAME [IUPAC:] -synonym: "heteroarenes" EXACT IUPAC_NAME [IUPAC] -is_a: CHEBI:24532 ! organic heterocyclic compound -is_a: CHEBI:33659 ! organic aromatic compound - -[Term] -id: CHEBI:33837 -name: conjugated protein -namespace: chebi_ontology -def: "Conjugated protein is a protein that contains a non-peptide component, usually in stoichiometric proportion." [] -subset: 3_STAR -synonym: "complex protein" RELATED [COMe] -synonym: "conjugated proteins" EXACT IUPAC_NAME [IUPAC] -xref: COMe:PRX000001 -is_a: CHEBI:36080 ! protein -is_a: PR:000000001 ! protein - -[Term] -id: CHEBI:33839 -name: macromolecule -namespace: chebi_ontology -def: "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [] -subset: 3_STAR -synonym: "macromolecule" EXACT IUPAC_NAME [IUPAC] -synonym: "macromolecules" RELATED [ChEBI] -synonym: "polymer" RELATED [ChEBI] -synonym: "polymer molecule" RELATED [IUPAC] -synonym: "polymers" RELATED [ChEBI] -xref: Wikipedia:Macromolecule -is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:33853 -name: phenols namespace: chebi_ontology -alt_id: CHEBI:13664 -alt_id: CHEBI:13825 -alt_id: CHEBI:25969 -alt_id: CHEBI:2857 def: "Compounds having one or more hydroxy groups attached to a benzene or other arene ring." [ANON:ANON] -def: "Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring." [] -subset: 3_STAR -synonym: "a phenol" RELATED [UniProt] -synonym: "arenols" RELATED [IUPAC] synonym: "arenols" RELATED [IUPAC:] synonym: "Aryl alcohol" RELATED [KEGG COMPOUND:] -synonym: "Aryl alcohol" RELATED [KEGG_COMPOUND] synonym: "aryl alcohol" RELATED [UniProt:] -synonym: "phenols" EXACT IUPAC_NAME [IUPAC] synonym: "phenols" EXACT IUPAC_NAME [IUPAC:] -xref: KEGG:C15584 -xref: MetaCyc:Phenols -xref: Wikipedia:Phenols -is_a: CHEBI:33659 ! organic aromatic compound -is_a: CHEBI:33822 ! organic hydroxy compound -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C6HOR5" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "89.072" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "89.00274" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1(=C(C(=C(C(=C1*)*)*)*)*)O" xsd:string - -[Term] -id: CHEBI:33893 -name: reagent -namespace: chebi_ontology -def: "A substance used in a chemical reaction to detect, measure, examine, or produce other substances." [] -subset: 3_STAR -synonym: "reactif" RELATED [IUPAC] -synonym: "reactivo" RELATED [IUPAC] -synonym: "reagent" EXACT IUPAC_NAME [IUPAC] -synonym: "reagents" RELATED [ChEBI] -is_a: CHEBI:33232 ! application - -[Term] -id: CHEBI:33917 -name: aldohexose -namespace: chebi_ontology -alt_id: CHEBI:2558 -def: "A hexose with a (potential) aldehyde group at one end." [] -subset: 3_STAR -synonym: "aldohexose" EXACT [ChEBI] -synonym: "aldohexoses" RELATED [ChEBI] -is_a: CHEBI:15693 ! aldose -is_a: CHEBI:18133 ! hexose - -[Term] -id: CHEBI:33937 -name: macronutrient -namespace: chebi_ontology -def: "Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals." [] -subset: 3_STAR -synonym: "macronutrients" RELATED [ChEBI] -is_a: CHEBI:33284 ! nutrient - -[Term] -id: CHEBI:350546 -name: serotonin(1+) -namespace: chebi_ontology -def: "An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3." [] -subset: 3_STAR -synonym: "2-(5-hydroxy-1H-indol-3-yl)ethanaminium" EXACT IUPAC_NAME [IUPAC] -synonym: "serotonin" RELATED [UniProt] -synonym: "serotonin cation" RELATED [ChEBI] -is_a: CHEBI:35274 ! ammonium ion derivative -relationship: is_conjugate_acid_of CHEBI:28790 ! serotonin -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H13N2O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2/p+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QZAYGJVTTNCVMB-UHFFFAOYSA-O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "177.22250" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "177.10224" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]CCc1c[nH]c2ccc(O)cc12" xsd:string - -[Term] -id: CHEBI:35106 -name: nitrogen hydride -namespace: chebi_ontology -subset: 3_STAR -synonym: "nitrogen hydrides" RELATED [ChEBI] -is_a: CHEBI:35881 ! pnictogen hydride -is_a: CHEBI:51143 ! nitrogen molecular entity - -[Term] -id: CHEBI:35107 -name: azane -namespace: chebi_ontology -def: "Saturated acyclic nitrogen hydrides having the general formula NnHn+2." [] -subset: 3_STAR -synonym: "azanes" RELATED [ChEBI] -is_a: CHEBI:35106 ! nitrogen hydride - -[Term] -id: CHEBI:35155 -name: elemental calcium -namespace: chebi_ontology -subset: 3_STAR -is_a: CHEBI:22985 ! calcium molecular entity - -[Term] -id: CHEBI:35186 -name: terpene -namespace: chebi_ontology -def: "A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH2=C(CH3)CH=CH2]." [] -subset: 3_STAR -synonym: "Terpen" RELATED [ChEBI] -synonym: "terpene" EXACT [IUPAC] -synonym: "terpenes" EXACT IUPAC_NAME [IUPAC] -synonym: "terpenes" RELATED [IUPAC] -synonym: "terpeno" RELATED [IUPAC] -synonym: "terpenos" RELATED [IUPAC] -is_a: CHEBI:24632 ! hydrocarbon -is_a: CHEBI:24913 ! isoprenoid - -[Term] -id: CHEBI:35189 -name: sesquiterpene -namespace: chebi_ontology -def: "A C15 terpene." [] -subset: 3_STAR -synonym: "Sesquiterpen" RELATED [ChEBI] -synonym: "sesquiterpenes" EXACT IUPAC_NAME [IUPAC] -synonym: "sesquiterpenes" RELATED [IUPAC] -synonym: "sesquiterpeno" RELATED [IUPAC] -synonym: "sesquiterpenos" RELATED [IUPAC] -is_a: CHEBI:35186 ! terpene - -[Term] -id: CHEBI:35191 -name: triterpene -namespace: chebi_ontology -def: "A C30 terpene." [] -subset: 3_STAR -synonym: "Triterpen" RELATED [ChEBI] -synonym: "triterpenes" EXACT IUPAC_NAME [IUPAC] -synonym: "triterpenes" RELATED [IUPAC] -synonym: "triterpeno" RELATED [IUPAC] -synonym: "triterpenos" RELATED [IUPAC] -is_a: CHEBI:35186 ! terpene - -[Term] -id: CHEBI:35196 -name: nitrogen oxide -namespace: chebi_ontology -subset: 3_STAR -synonym: "nitrogen oxides" RELATED [ChEBI] -synonym: "oxides of nitrogen" RELATED [ChEBI] -is_a: CHEBI:24836 ! inorganic oxide -is_a: CHEBI:51143 ! nitrogen molecular entity - -[Term] -id: CHEBI:35222 -name: inhibitor -namespace: chebi_ontology -def: "A substance that diminishes the rate of a chemical reaction." [] -subset: 3_STAR -synonym: "inhibidor" RELATED [ChEBI] -synonym: "inhibiteur" RELATED [ChEBI] -synonym: "inhibitor" EXACT IUPAC_NAME [IUPAC] -synonym: "inhibitors" RELATED [ChEBI] -is_a: CHEBI:24432 ! biological role - -[Term] -id: CHEBI:35223 -name: catalyst -namespace: chebi_ontology -def: "A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction." [] -subset: 3_STAR -synonym: "catalizador" RELATED [ChEBI] -synonym: "catalyseur" RELATED [ChEBI] -synonym: "catalyst" EXACT IUPAC_NAME [IUPAC] -synonym: "Katalysator" RELATED [ChEBI] -is_a: CHEBI:51086 ! chemical role - -[Term] -id: CHEBI:35238 -name: amino acid zwitterion -namespace: chebi_ontology -def: "The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group." [] -subset: 3_STAR -synonym: "amino acid zwitterion" EXACT [ChEBI] -is_a: CHEBI:27369 ! zwitterion - -[Term] -id: CHEBI:35267 -name: quaternary ammonium ion -namespace: chebi_ontology -alt_id: CHEBI:26470 -alt_id: CHEBI:8693 -def: "A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually hydrocarbyl) groups." [ANON:ANON] -def: "A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." [] -subset: 3_STAR -synonym: "[*][N+]([*])([*])[*]" RELATED SMILES [ChEBI:] -synonym: "a quaternary ammonium" RELATED [UniProt] -synonym: "NR4" RELATED FORMULA [ChEBI:] -synonym: "Quaternary amine" RELATED [KEGG COMPOUND:] -synonym: "Quaternary amine" RELATED [KEGG_COMPOUND] -synonym: "quaternary ammonium ion" EXACT IUPAC_NAME [IUPAC] -synonym: "quaternary ammonium ion" EXACT IUPAC_NAME [IUPAC:] -synonym: "quaternary ammonium ions" RELATED [ChEBI:] -synonym: "quaternary ammonium ions" RELATED [ChEBI] -xref: KEGG:C06703 -is_a: CHEBI:25697 ! organic cation -is_a: CHEBI:35274 ! ammonium ion derivative -property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "NR4" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "14.00670" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "14.00307" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*][N+]([*])([*])[*]" xsd:string - -[Term] -id: CHEBI:35274 -name: ammonium ion derivative -namespace: chebi_ontology -def: "A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc)." [] -def: "Ammonium, NH4(+), and derivatives formed by substitution by univalent groups." [ANON:ANON] -subset: 3_STAR -synonym: "ammonium ion derivatives" RELATED [ChEBI] -synonym: "ammonium ions" RELATED [ChEBI:] -synonym: "azanium ion derivative" RELATED [ChEBI] -synonym: "azanium ion derivatives" RELATED [ChEBI] -synonym: "azanium ions" RELATED [ChEBI:] -is_a: CHEBI:33702 ! polyatomic cation -is_a: CHEBI:51143 ! nitrogen molecular entity -relationship: has_parent_hydride CHEBI:28938 ! ammonium - -[Term] -id: CHEBI:35287 -name: acylcholine -namespace: chebi_ontology -alt_id: CHEBI:13245 -alt_id: CHEBI:22227 -alt_id: CHEBI:2463 -def: "A choline ester formed from choline and a carboxylic acid." [ANON:ANON] -subset: 3_STAR -synonym: "acylcholine" EXACT [UniProt:] -synonym: "acylcholines" RELATED [ChEBI:] -synonym: "acylcholines" RELATED [ChEBI] -synonym: "an acylcholine" RELATED [UniProt] -synonym: "C6H13NO2R" RELATED FORMULA [KEGG COMPOUND:] -synonym: "C[N+](C)(C)CCOC([*])=O" RELATED SMILES [ChEBI:] -xref: KEGG:C01777 -is_a: CHEBI:35267 ! quaternary ammonium ion -property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H13NO2R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "131.17290" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "131.09463" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C[N+](C)(C)CCOC([*])=O" xsd:string - -[Term] -id: CHEBI:35341 -name: steroid -namespace: chebi_ontology -alt_id: CHEBI:13687 -alt_id: CHEBI:26768 -alt_id: CHEBI:9263 -def: "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene." [] -subset: 3_STAR -synonym: "a steroid" RELATED [UniProt] -synonym: "Steroid" EXACT [KEGG_COMPOUND] -synonym: "steroids" EXACT IUPAC_NAME [IUPAC] -xref: KEGG:C00377 -xref: MetaCyc:Steroids -is_a: CHEBI:18059 ! lipid -is_a: CHEBI:51958 ! organic polycyclic compound -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C19H31R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "259.450" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "259.24258" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C12C(C3C(C(CC3)*)(C)CC1)CCC4C2(CCCC4)C" xsd:string - -[Term] -id: CHEBI:35343 -name: 17beta-hydroxy steroid -namespace: chebi_ontology -alt_id: CHEBI:19176 -alt_id: CHEBI:794 -def: "A 17-hydroxy steroid in which the hydroxy group at position 17 has a beta-configuration." [] -subset: 3_STAR -synonym: "17beta-hydroxy steroids" RELATED [ChEBI] -synonym: "17beta-hydroxysteroid" RELATED [KEGG_COMPOUND] -synonym: "17beta-hydroxysteroids" RELATED [ChEBI] -synonym: "a 17beta-hydroxy steroid" RELATED [UniProt] -xref: KEGG:C03051 -xref: MetaCyc:17-beta-Hydroxysteroids -is_a: CHEBI:36838 ! 17-hydroxy steroid -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C18H29OR" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "261.423" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "261.22184" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC12CCC3C(CCC4CCCCC34[*])C1CC[C@@H]2O" xsd:string - -[Term] -id: CHEBI:35344 -name: 21-hydroxy steroid -namespace: chebi_ontology -alt_id: CHEBI:1300 -alt_id: CHEBI:13596 -alt_id: CHEBI:19803 -subset: 3_STAR -synonym: "21-hydroxy steroids" RELATED [ChEBI] -synonym: "21-Hydroxysteroid" RELATED [KEGG_COMPOUND] -synonym: "21-hydroxysteroids" RELATED [ChEBI] -xref: KEGG:C02506 -is_a: CHEBI:35350 ! hydroxy steroid - -[Term] -id: CHEBI:35346 -name: 11beta-hydroxy steroid -namespace: chebi_ontology -alt_id: CHEBI:13774 -alt_id: CHEBI:19134 -alt_id: CHEBI:738 -def: "Any 11-hydroxy steroid in which the hydroxy group at position 11 has beta- configuration." [] -subset: 3_STAR -synonym: "11beta-hydroxy steroids" RELATED [ChEBI] -synonym: "11beta-Hydroxysteroid" RELATED [KEGG_COMPOUND] -synonym: "11beta-hydroxysteroids" RELATED [ChEBI] -synonym: "an 11beta-hydroxysteroid" RELATED [UniProt] -xref: KEGG:C01058 -is_a: CHEBI:36841 ! 11-hydroxy steroid -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C19H31OR" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "275.450" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "275.23749" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C12(CCCCC1CCC3C2[C@H](CC4(C3CCC4*)C)O)C" xsd:string - -[Term] -id: CHEBI:35350 -name: hydroxy steroid -namespace: chebi_ontology -alt_id: CHEBI:24748 -alt_id: CHEBI:5814 -subset: 3_STAR -synonym: "hydroxy steroids" RELATED [ChEBI] -synonym: "Hydroxysteroid" RELATED [KEGG_COMPOUND] -synonym: "hydroxysteroids" RELATED [ChEBI] -xref: KEGG:C02159 -is_a: CHEBI:33822 ! organic hydroxy compound -is_a: CHEBI:35341 ! steroid [Term] id: CHEBI:35352 -name: organonitrogen compound namespace: chebi_ontology def: "Any heteroorganic entity containing at least one carbon-nitrogen bond." [ANON:ANON] -subset: 3_STAR synonym: "organonitrogen compounds" EXACT IUPAC_NAME [IUPAC:] -synonym: "organonitrogen compounds" EXACT IUPAC_NAME [IUPAC] synonym: "organonitrogens" RELATED [ChEBI:] -synonym: "organonitrogens" RELATED [ChEBI] -is_a: CHEBI:33285 ! heteroorganic entity -is_a: CHEBI:51143 ! nitrogen molecular entity - -[Term] -id: CHEBI:35366 -name: fatty acid -namespace: chebi_ontology -alt_id: CHEBI:13633 -alt_id: CHEBI:24024 -alt_id: CHEBI:4984 -def: "Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax." [ANON:ANON] -def: "Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids." [] -subset: 3_STAR -synonym: "acide gras" RELATED [ChEBI:] -synonym: "acide gras" RELATED [ChEBI] -synonym: "acides gras" RELATED [ChemIDplus] -synonym: "acides gras" RELATED [ChemIDplus:] -synonym: "acido graso" RELATED [ChEBI:] -synonym: "acido graso" RELATED [ChEBI] -synonym: "acidos grasos" RELATED [ChEBI:] -synonym: "acidos grasos" RELATED [ChEBI] -synonym: "CHO2R" RELATED FORMULA [KEGG COMPOUND:] -synonym: "Fatty acid" EXACT [KEGG COMPOUND:] -synonym: "Fatty acid" EXACT [KEGG_COMPOUND] -synonym: "fatty acids" EXACT IUPAC_NAME [IUPAC] -synonym: "fatty acids" EXACT IUPAC_NAME [IUPAC:] -synonym: "fatty acids" RELATED [ChEBI:] -synonym: "fatty acids" RELATED [ChEBI] -synonym: "Fettsaeure" RELATED [ChEBI:] -synonym: "Fettsaeure" RELATED [ChEBI] -synonym: "Fettsaeuren" RELATED [ChEBI:] -synonym: "Fettsaeuren" RELATED [ChEBI] -synonym: "OC([*])=O" RELATED SMILES [ChEBI:] -xref: KEGG:C00162 -xref: PMID:14287444 {source="Europe PMC"} -xref: PMID:14300208 {source="Europe PMC"} -xref: PMID:14328676 {source="Europe PMC"} -xref: Wikipedia:Fatty_acid -is_a: CHEBI:18059 ! lipid -is_a: CHEBI:25384 ! monocarboxylic acid -relationship: is_conjugate_acid_of CHEBI:28868 ! fatty acid anion -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO2R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "45.01740" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.99765" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC([*])=O" xsd:string - -[Term] -id: CHEBI:35381 -name: monosaccharide -namespace: chebi_ontology -alt_id: CHEBI:25407 -alt_id: CHEBI:6984 -def: "Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group." [] -subset: 3_STAR -synonym: "monosacarido" RELATED [ChEBI] -synonym: "monosacaridos" RELATED [IUPAC] -synonym: "Monosaccharid" RELATED [ChEBI] -synonym: "Monosaccharide" EXACT [KEGG_COMPOUND] -synonym: "monosaccharides" EXACT IUPAC_NAME [IUPAC] -synonym: "Monosacharid" RELATED [ChEBI] -xref: KEGG:C06698 -is_a: CHEBI:16646 ! carbohydrate - -[Term] -id: CHEBI:35406 -name: oxoanion -namespace: chebi_ontology -alt_id: CHEBI:33274 -alt_id: CHEBI:33436 -def: "An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen." [] -subset: 3_STAR -synonym: "oxoacid anions" RELATED [ChEBI] -synonym: "oxoanion" EXACT [ChEBI] -synonym: "oxoanions" RELATED [ChEBI] -is_a: CHEBI:25741 ! oxide -is_a: CHEBI:33273 ! polyatomic anion - -[Term] -id: CHEBI:35470 -name: central nervous system drug -namespace: chebi_ontology -def: "A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system." [] -subset: 3_STAR -synonym: "central nervous system agents" RELATED [ChEBI] -synonym: "CNS agent" RELATED [ChEBI] -synonym: "CNS drugs" RELATED [ChEBI] -is_a: CHEBI:23888 ! drug - -[Term] -id: CHEBI:35472 -name: anti-inflammatory drug -namespace: chebi_ontology -def: "A substance that reduces or suppresses inflammation." [] -subset: 3_STAR -synonym: "anti-inflammatory drugs" RELATED [ChEBI] -synonym: "antiinflammatory agent" RELATED [ChEBI] -synonym: "antiinflammatory drug" RELATED [ChEBI] -synonym: "antiinflammatory drugs" RELATED [ChEBI] -is_a: CHEBI:23888 ! drug -is_a: CHEBI:67079 ! anti-inflammatory agent - -[Term] -id: CHEBI:35479 -name: alkali metal salt -namespace: chebi_ontology -subset: 3_STAR -synonym: "alkali metal salts" RELATED [ChEBI] -is_a: CHEBI:24866 ! salt -is_a: CHEBI:33296 ! alkali metal molecular entity - -[Term] -id: CHEBI:35488 -name: central nervous system depressant -namespace: chebi_ontology -def: "A loosely defined group of drugs that tend to reduce the activity of the central nervous system." [] -subset: 3_STAR -synonym: "central nervous system depressants" RELATED [ChEBI] -synonym: "CNS depressants" RELATED [ChEBI] -is_a: CHEBI:35470 ! central nervous system drug - -[Term] -id: CHEBI:35507 -name: natural product fundamental parent -namespace: chebi_ontology -subset: 3_STAR -synonym: "natural product fundamental parents" EXACT IUPAC_NAME [IUPAC] -is_a: CHEBI:33245 ! organic fundamental parent - -[Term] -id: CHEBI:35508 -name: steroid fundamental parent -namespace: chebi_ontology -subset: 3_STAR -synonym: "steroid fundamental parents" RELATED [ChEBI] -is_a: CHEBI:35341 ! steroid -is_a: CHEBI:35507 ! natural product fundamental parent - -[Term] -id: CHEBI:35509 -name: androstane -namespace: chebi_ontology -subset: 3_STAR -synonym: "androstane" EXACT IUPAC_NAME [IUPAC] -xref: Beilstein:5247532 {source="Beilstein"} -xref: CAS:24887-75-0 {source="ChemIDplus"} -xref: LIPID_MAPS_instance:LMST02020000 {source="LIPID MAPS"} -is_a: CHEBI:35508 ! steroid fundamental parent -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C19H32" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C19H32/c1-18-11-5-7-16(18)15-9-8-14-6-3-4-12-19(14,2)17(15)10-13-18/h14-17H,3-13H2,1-2H3/t14?,15-,16-,17-,18-,19-/m0/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QZLYKIGBANMMBK-FZFXZXLVSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "260.45738" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "260.25040" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]12CCC3CCCC[C@]3(C)[C@@]1([H])CC[C@]1(C)CCC[C@@]21[H]" xsd:string - -[Term] -id: CHEBI:35519 -name: cholane -namespace: chebi_ontology -subset: 3_STAR -synonym: "cholane" EXACT IUPAC_NAME [IUPAC] -is_a: CHEBI:35508 ! steroid fundamental parent -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C24H42" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C24H42/c1-5-8-17(2)20-12-13-21-19-11-10-18-9-6-7-15-23(18,3)22(19)14-16-24(20,21)4/h17-22H,5-16H2,1-4H3/t17-,18?,19+,20-,21+,22+,23+,24-/m1/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QSHQKIURKJITMZ-BRPMRXRMSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "330.59028" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "330.32865" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4CCCC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC" xsd:string - -[Term] -id: CHEBI:35522 -name: beta-adrenergic agonist -namespace: chebi_ontology -def: "An agent that selectively binds to and activates beta-adrenergic receptors." [] -subset: 3_STAR -synonym: "beta-adrenergic agonists" RELATED [ChEBI] -synonym: "beta-adrenergic receptor agonist" RELATED [ChEBI] -synonym: "beta-adrenoceptor agonists" RELATED [IUPHAR] -is_a: CHEBI:37886 ! adrenergic agonist -is_a: CHEBI:48540 ! beta-adrenergic drug - -[Term] -id: CHEBI:35523 -name: bronchodilator agent -namespace: chebi_ontology -def: "An agent that causes an increase in the expansion of a bronchus or bronchial tubes." [] -subset: 3_STAR -synonym: "bronchodilator" RELATED [ChEBI] -synonym: "bronchodilator agents" RELATED [ChEBI] -synonym: "broncholytic agent" RELATED [ChEBI] -is_a: CHEBI:23888 ! drug - -[Term] -id: CHEBI:35524 -name: sympathomimetic agent -namespace: chebi_ontology -def: "A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters." [] -subset: 3_STAR -synonym: "sympathomimetic" RELATED [ChEBI] -synonym: "sympathomimetics" RELATED [ChEBI] -is_a: CHEBI:37962 ! adrenergic agent - -[Term] -id: CHEBI:35554 -name: cardiovascular drug -namespace: chebi_ontology -def: "A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume." [] -subset: 3_STAR -synonym: "cardiovascular agent" RELATED [ChEBI] -synonym: "cardiovascular drugs" RELATED [ChEBI] -is_a: CHEBI:23888 ! drug - -[Term] -id: CHEBI:35569 -name: alpha-adrenergic agonist -namespace: chebi_ontology -def: "An agent that selectively binds to and activates alpha-adrenergic receptors." [] -subset: 3_STAR -synonym: "alpha-adrenergic agonists" RELATED [ChEBI] -synonym: "alpha-adrenergic receptor agonist" RELATED [ChEBI] -synonym: "alpha-adrenoceptor agonists" RELATED [IUPHAR] -is_a: CHEBI:37886 ! adrenergic agonist -is_a: CHEBI:48539 ! alpha-adrenergic drug - -[Term] -id: CHEBI:35604 -name: carbon oxoanion -namespace: chebi_ontology -def: "A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n." [] -subset: 3_STAR -synonym: "carbon oxoanion" EXACT [ChEBI] -synonym: "carbon oxoanions" RELATED [ChEBI] -synonym: "oxocarbon anion" RELATED [ChEBI] -synonym: "oxocarbon anions" RELATED [ChEBI] -is_a: CHEBI:25696 ! organic anion -is_a: CHEBI:35406 ! oxoanion -is_a: CHEBI:36963 ! organooxygen compound - -[Term] -id: CHEBI:35605 -name: carbon oxoacid -namespace: chebi_ontology -subset: 3_STAR -synonym: "carbon oxoacids" RELATED [ChEBI] -synonym: "oxoacids of carbon" RELATED [ChEBI] -is_a: CHEBI:24833 ! oxoacid -is_a: CHEBI:36963 ! organooxygen compound - -[Term] -id: CHEBI:35610 -name: antineoplastic agent -namespace: chebi_ontology -def: "A substance that inhibits or prevents the proliferation of neoplasms." [] -subset: 3_STAR -synonym: "anticancer agent" RELATED [ChEBI] -synonym: "anticancer agents" RELATED [ChEBI] -synonym: "antineoplastic" RELATED [ChEBI] -synonym: "antineoplastic agents" RELATED [ChEBI] -synonym: "cytostatic" RELATED [ChEBI] -is_a: CHEBI:23888 ! drug - -[Term] -id: CHEBI:35620 -name: vasodilator agent -namespace: chebi_ontology -def: "A drug used to cause dilation of the blood vessels." [] -subset: 3_STAR -synonym: "vasodilator" RELATED [ChEBI] -synonym: "vasodilator agents" RELATED [ChEBI] -is_a: CHEBI:35554 ! cardiovascular drug - -[Term] -id: CHEBI:35623 -name: anticonvulsant -namespace: chebi_ontology -def: "A drug used to prevent seizures or reduce their severity." [] -subset: 3_STAR -synonym: "anti-convulsant" RELATED [ChEBI] -synonym: "anti-convulsants" RELATED [ChEBI] -synonym: "anti-convulsive agent" RELATED [ChEBI] -synonym: "anti-convulsive agents" RELATED [ChEBI] -synonym: "anticonvulsants" RELATED [ChEBI] -synonym: "anticonvulsive agent" RELATED [ChEBI] -synonym: "anticonvulsive agents" RELATED [ChEBI] -synonym: "antiepileptic" RELATED [ChEBI] -synonym: "antiepileptics" RELATED [ChEBI] -synonym: "Antiepileptika" RELATED [ChEBI] -synonym: "Antiepileptikum" RELATED [ChEBI] -synonym: "antiepileptique" RELATED [ChEBI] -synonym: "antiepileptiques" RELATED [ChEBI] -synonym: "Antikonvulsiva" RELATED [ChEBI] -synonym: "Antikonvulsivum" RELATED [ChEBI] -is_a: CHEBI:35488 ! central nervous system depressant - -[Term] -id: CHEBI:35692 -name: dicarboxylic acid -namespace: chebi_ontology -alt_id: CHEBI:23692 -alt_id: CHEBI:36172 -alt_id: CHEBI:4501 -def: "Any carboxylic acid containing two carboxy groups." [] -subset: 3_STAR -synonym: "Dicarboxylic acid" EXACT [KEGG_COMPOUND] -synonym: "dicarboxylic acids" RELATED [ChEBI] -xref: KEGG:C02028 -is_a: CHEBI:131927 ! dicarboxylic acids and O-substituted derivatives -is_a: CHEBI:33575 ! carboxylic acid -relationship: is_conjugate_acid_of CHEBI:35693 ! dicarboxylic acid anion - -[Term] -id: CHEBI:35693 -name: dicarboxylic acid anion -namespace: chebi_ontology -subset: 3_STAR -synonym: "dicarboxylic acid anion" EXACT [ChEBI] -synonym: "dicarboxylic acid anions" RELATED [ChEBI] -is_a: CHEBI:29067 ! carboxylic acid anion -relationship: is_conjugate_base_of CHEBI:35692 ! dicarboxylic acid - -[Term] -id: CHEBI:35701 -name: ester -namespace: chebi_ontology -alt_id: CHEBI:23960 -alt_id: CHEBI:4859 -def: "A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter." [ANON:ANON] -subset: 3_STAR -synonym: "Ester" EXACT [KEGG_COMPOUND] -synonym: "Ester" EXACT [KEGG COMPOUND:] -synonym: "esters" RELATED [ChEBI:] -synonym: "esters" RELATED [ChEBI] -xref: KEGG:C00287 -xref: Wikipedia:Ester -is_a: CHEBI:36963 ! organooxygen compound - -[Term] -id: CHEBI:35722 -name: sulfated glycosaminoglycan -namespace: chebi_ontology -subset: 3_STAR -synonym: "glycosaminoglycan sulfate" RELATED [ChEBI] -synonym: "glycosaminoglycan sulfates" RELATED [ChEBI] -synonym: "sulfated glycosaminoglycans" RELATED [ChEBI] -is_a: CHEBI:18085 ! glycosaminoglycan -is_a: CHEBI:35724 ! carbohydrate sulfate - -[Term] -id: CHEBI:35724 -name: carbohydrate sulfate -namespace: chebi_ontology -subset: 3_STAR -synonym: "carbohydrate sulfates" RELATED [ChEBI] -synonym: "carbohydrate sulphates" RELATED [ChEBI] -is_a: CHEBI:25704 ! organic sulfate -is_a: CHEBI:26819 ! sulfuric ester -is_a: CHEBI:63299 ! carbohydrate derivative - -[Term] -id: CHEBI:35740 -name: liposaccharide -namespace: chebi_ontology -subset: 3_STAR -synonym: "liposaccharides" RELATED [ChEBI] -is_a: CHEBI:18059 ! lipid -is_a: CHEBI:63299 ! carbohydrate derivative - -[Term] -id: CHEBI:35757 -name: monocarboxylic acid anion -namespace: chebi_ontology -alt_id: CHEBI:13657 -alt_id: CHEBI:25382 -alt_id: CHEBI:3407 -def: "A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated." [] -subset: 3_STAR -synonym: "a monocarboxylate" RELATED [UniProt] -synonym: "Carboxylate" RELATED [KEGG_COMPOUND] -synonym: "Monocarboxylate" RELATED [KEGG_COMPOUND] -synonym: "monocarboxylates" RELATED [ChEBI] -synonym: "monocarboxylic acid anions" RELATED [ChEBI] -xref: KEGG:C00060 -is_a: CHEBI:29067 ! carboxylic acid anion -relationship: is_conjugate_base_of CHEBI:25384 ! monocarboxylic acid -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "44.01000" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([*])=O" xsd:string - -[Term] -id: CHEBI:35780 -name: phosphate ion -namespace: chebi_ontology -def: "A phosphorus oxoanion that is the conjugate base of phosphoric acid." [] -subset: 3_STAR -synonym: "phosphate" RELATED [ChEBI] -synonym: "phosphate ions" RELATED [ChEBI] -synonym: "Pi" RELATED [ChEBI] -is_a: CHEBI:33461 ! phosphorus oxoanion -relationship: is_conjugate_base_of CHEBI:26078 ! phosphoric acid -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite - -[Term] -id: CHEBI:35789 -name: oxo steroid -namespace: chebi_ontology -alt_id: CHEBI:24979 -alt_id: CHEBI:25804 -subset: 3_STAR -synonym: "keto steroids" RELATED [ChEBI] -synonym: "ketosteroids" RELATED [ChEBI] -synonym: "oxo steroids" RELATED [ChEBI] -synonym: "oxosteroids" RELATED [ChEBI] -is_a: CHEBI:17087 ! ketone -is_a: CHEBI:35341 ! steroid - -[Term] -id: CHEBI:35881 -name: pnictogen hydride -namespace: chebi_ontology -subset: 3_STAR -synonym: "pnictogen hydride" EXACT [ChEBI] -synonym: "pnictogen hydrides" RELATED [ChEBI] -is_a: CHEBI:33242 ! inorganic hydride -is_a: CHEBI:33302 ! pnictogen molecular entity - -[Term] -id: CHEBI:35942 -name: neurotransmitter agent -namespace: chebi_ontology -def: "A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function." [] -subset: 3_STAR -synonym: "neurotransmitter agents" RELATED [ChEBI] -is_a: CHEBI:23888 ! drug -is_a: CHEBI:52210 ! pharmacological role - -[Term] -id: CHEBI:36063 -name: oxytocic -namespace: chebi_ontology -def: "A drug that stimulates contraction of the myometrium. Oxytocics are used to induce labour, obstetric at term, to prevent or control postpartum or postabortion haemorrhage, and to assess foetal status in high risk pregnancies. They may also be used alone or with other drugs to induce abortions (abortifacients)." [] -subset: 3_STAR -synonym: "oxytocic" EXACT [ChEBI] -synonym: "oxytocic agents" RELATED [ChEBI] -synonym: "oxytocic drugs" RELATED [ChEBI] -synonym: "uterine stimulants" RELATED [ChEBI] -is_a: CHEBI:23888 ! drug - -[Term] -id: CHEBI:36078 -name: cholanoid -namespace: chebi_ontology -alt_id: CHEBI:22867 -alt_id: CHEBI:50419 -subset: 3_STAR -synonym: "bile acids and derivatives" RELATED [LIPID_MAPS] -synonym: "cholanoids" RELATED [ChEBI] -xref: LIPID_MAPS_class:LMST04 {source="LIPID MAPS"} -is_a: CHEBI:35341 ! steroid -relationship: has_parent_hydride CHEBI:35519 ! cholane [Term] id: CHEBI:36080 -name: protein -namespace: chebi_ontology -alt_id: CHEBI:13677 -alt_id: CHEBI:14911 -def: "A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome." [] -subset: 3_STAR -synonym: "proteins" EXACT IUPAC_NAME [IUPAC] is_a: PR:000000001 ! protein equivalent_to: PR:000000001 ! protein -[Term] -id: CHEBI:36235 -name: bile acid anion -namespace: chebi_ontology -subset: 3_STAR -synonym: "bile acid anions" RELATED [ChEBI] -is_a: CHEBI:35757 ! monocarboxylic acid anion -is_a: CHEBI:50160 ! steroid acid anion - -[Term] -id: CHEBI:36237 -name: cholanic acid -namespace: chebi_ontology -def: "A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24." [] -subset: 3_STAR -synonym: "cholan-24-oic acid" EXACT IUPAC_NAME [IUPAC] -xref: CAS:25312-65-6 {source="ChemIDplus"} -xref: Patent:JP2008069152 -xref: Reaxys:13246008 {source="Reaxys"} -is_a: CHEBI:36278 ! cholanic acids -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C24H40O2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17?,18+,19-,20+,21+,23+,24-/m1/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "RPKLZQLYODPWTM-KBMWBBLPSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "360.57320" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "360.30283" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4CCCC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(O)=O" xsd:string - -[Term] -id: CHEBI:36238 -name: 5beta-cholanic acid -namespace: chebi_ontology -subset: 3_STAR -synonym: "(5beta)-cholan-24-oic acid" RELATED [ChemIDplus] -synonym: "(5beta,17beta)-gamma-methylandrostane-17-butanoic acid" RELATED [ChemIDplus] -synonym: "5beta-cholan-24-oic acid" EXACT IUPAC_NAME [IUPAC] -synonym: "5beta-cholanic acid" EXACT [ChemIDplus] -synonym: "5beta-cholanoic acid" RELATED [ChemIDplus] -synonym: "ursocholanic acid" RELATED [ChemIDplus] -xref: Beilstein:3214794 {source="Beilstein"} -xref: CAS:546-18-9 {source="ChemIDplus"} -xref: LIPID_MAPS_instance:LMST04010441 {source="LIPID MAPS"} -is_a: CHEBI:36237 ! cholanic acid -is_a: CHEBI:36248 ! 5beta-cholanic acids -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C24H40O2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17+,18+,19-,20+,21+,23+,24-/m1/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "RPKLZQLYODPWTM-LVVAJZGHSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "360.57320" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "360.30283" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]12CCCC[C@]1(C)[C@@]1([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC2)[C@H](C)CCC(O)=O" xsd:string - -[Term] -id: CHEBI:36248 -name: 5beta-cholanic acids -namespace: chebi_ontology -def: "Members of the class of cholanic acids based on a 5beta-cholane skeleton." [] -subset: 3_STAR -is_a: CHEBI:136889 ! 5beta steroid -is_a: CHEBI:36278 ! cholanic acids -relationship: has_parent_hydride CHEBI:20664 ! 5beta-cholane - -[Term] -id: CHEBI:36277 -name: bile acid salt -namespace: chebi_ontology -def: "A salt of a bile acid." [] -subset: 3_STAR -synonym: "bile acid salts" RELATED [ChEBI] -is_a: CHEBI:24868 ! organic salt -is_a: CHEBI:36078 ! cholanoid - -[Term] -id: CHEBI:36278 -name: cholanic acids -namespace: chebi_ontology -alt_id: CHEBI:23166 -alt_id: CHEBI:23211 -subset: 1_STAR -is_a: CHEBI:36078 ! cholanoid -is_a: CHEBI:47891 ! steroid acid - -[Term] -id: CHEBI:36338 -name: lepton -namespace: chebi_ontology -def: "Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin)." [] -subset: 3_STAR -synonym: "leptons" RELATED [ChEBI] -is_a: CHEBI:33233 ! fundamental particle -is_a: CHEBI:36340 ! fermion - -[Term] -id: CHEBI:36339 -name: baryon -namespace: chebi_ontology -def: "Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy)." [] -subset: 3_STAR -synonym: "baryons" RELATED [ChEBI] -is_a: CHEBI:36340 ! fermion -is_a: CHEBI:36344 ! hadron - -[Term] -id: CHEBI:36340 -name: fermion -namespace: chebi_ontology -def: "Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi." [] -subset: 3_STAR -synonym: "fermion" EXACT IUPAC_NAME [IUPAC] -synonym: "fermions" RELATED [ChEBI] -is_a: CHEBI:36342 ! subatomic particle - -[Term] -id: CHEBI:36341 -name: boson -namespace: chebi_ontology -def: "Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose." [] -subset: 3_STAR -synonym: "boson" EXACT IUPAC_NAME [IUPAC] -synonym: "bosons" RELATED [ChEBI] -is_a: CHEBI:36342 ! subatomic particle - -[Term] -id: CHEBI:36342 -name: subatomic particle -namespace: chebi_ontology -def: "A particle smaller than an atom." [] -subset: 3_STAR -synonym: "subatomic particles" RELATED [ChEBI] -xref: Wikipedia:Subatomic_particle - -[Term] -id: CHEBI:36343 -name: composite particle -namespace: chebi_ontology -def: "A subatomic particle known to have substructure (i.e. consisting of smaller particles)." [] -subset: 3_STAR -synonym: "composite particles" RELATED [ChEBI] -is_a: CHEBI:36342 ! subatomic particle - -[Term] -id: CHEBI:36344 -name: hadron -namespace: chebi_ontology -def: "Hadron is a subatomic particle which experiences the strong force." [] -subset: 3_STAR -synonym: "hadrons" RELATED [ChEBI] -is_a: CHEBI:36343 ! composite particle - -[Term] -id: CHEBI:36347 -name: nuclear particle -namespace: chebi_ontology -def: "A nucleus or any of its constituents in any of their energy states." [] -subset: 3_STAR -synonym: "nuclear particle" EXACT IUPAC_NAME [IUPAC] -is_a: CHEBI:36342 ! subatomic particle - -[Term] -id: CHEBI:36357 -name: polyatomic entity -namespace: chebi_ontology -def: "Any molecular entity consisting of more than one atom." [ANON:ANON] -subset: 3_STAR -synonym: "polyatomic entities" RELATED [ChEBI:] -synonym: "polyatomic entities" RELATED [ChEBI] -is_a: CHEBI:23367 ! molecular entity -relationship: has_part CHEBI:24433 ! group - -[Term] -id: CHEBI:36358 -name: polyatomic ion -namespace: chebi_ontology -def: "An ion consisting of more than one atom." [ANON:ANON] -subset: 3_STAR -synonym: "polyatomic ions" RELATED [ChEBI] -synonym: "polyatomic ions" RELATED [ChEBI:] -is_a: CHEBI:24870 ! ion -is_a: CHEBI:36357 ! polyatomic entity - -[Term] -id: CHEBI:36359 -name: phosphorus oxoacid derivative -namespace: chebi_ontology -subset: 3_STAR -synonym: "phosphorus oxoacid derivative" EXACT [ChEBI] -is_a: CHEBI:33241 ! oxoacid derivative -is_a: CHEBI:36360 ! phosphorus oxoacids and derivatives -relationship: has_functional_parent CHEBI:33457 ! phosphorus oxoacid - -[Term] -id: CHEBI:36360 -name: phosphorus oxoacids and derivatives -namespace: chebi_ontology -subset: 1_STAR -is_a: CHEBI:26082 ! phosphorus molecular entity - -[Term] -id: CHEBI:36586 -name: carbonyl compound -namespace: chebi_ontology -def: "Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives." [ANON:ANON] -subset: 3_STAR -synonym: "carbonyl compounds" EXACT IUPAC_NAME [IUPAC:] -synonym: "carbonyl compounds" EXACT IUPAC_NAME [IUPAC] -is_a: CHEBI:36587 ! organic oxo compound -is_a: CHEBI:36963 ! organooxygen compound -relationship: has_part CHEBI:23019 ! carbonyl group - -[Term] -id: CHEBI:36587 -name: organic oxo compound -namespace: chebi_ontology -def: "Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element." [ANON:ANON] -subset: 3_STAR -synonym: "organic oxo compounds" RELATED [ChEBI] -synonym: "organic oxo compounds" RELATED [ChEBI:] -synonym: "oxo compounds" EXACT IUPAC_NAME [IUPAC:] -synonym: "oxo compounds" EXACT IUPAC_NAME [IUPAC] -is_a: CHEBI:72695 ! organic molecule -relationship: has_part CHEBI:46629 ! oxo group - -[Term] -id: CHEBI:36699 -name: corticosteroid hormone -namespace: chebi_ontology -def: "Any of a class of steroid hormones that are produced in the adrenal cortex." [] -subset: 3_STAR -synonym: "adrenal cortex hormones" RELATED [ChEBI] -synonym: "corticosteroid hormones" RELATED [ChEBI] -is_a: CHEBI:26764 ! steroid hormone -is_a: CHEBI:50858 ! corticosteroid - -[Term] -id: CHEBI:36735 -name: biladienes -namespace: chebi_ontology -def: "Compounds based on a biladiene skeleton." [] -subset: 3_STAR -is_a: CHEBI:25046 ! linear tetrapyrrole - -[Term] -id: CHEBI:36756 -name: farnesane -namespace: chebi_ontology -def: "A sesquiterpene that is dodecane substituted by methyl groups at positions 2, 6 and 10." [] -subset: 3_STAR -synonym: "2,6,10-trimethyldodecane" EXACT IUPAC_NAME [IUPAC] -synonym: "Farnesan" RELATED [NIST_Chemistry_WebBook] -synonym: "farnesane" EXACT [NIST_Chemistry_WebBook] -xref: Beilstein:1719672 {source="Beilstein"} -xref: CAS:3891-98-3 {source="NIST Chemistry WebBook"} -xref: CAS:3891-98-3 {source="ChemIDplus"} -xref: LIPID_MAPS_instance:LMPR0103010000 {source="LIPID MAPS"} -xref: MetaCyc:CPD-8764 -xref: Patent:US2008098645 -xref: Patent:US7399323 -xref: Reaxys:1719672 {source="Reaxys"} -is_a: CHEBI:18310 ! alkane -is_a: CHEBI:35189 ! sesquiterpene -relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C15H32" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C15H32/c1-6-14(4)10-8-12-15(5)11-7-9-13(2)3/h13-15H,6-12H2,1-5H3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "YFHFHLSMISYUAQ-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "212.41458" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "212.25040" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCC(C)CCCC(C)CCCC(C)C" xsd:string - -[Term] -id: CHEBI:36757 -name: farnesane sesquiterpenoid -namespace: chebi_ontology -subset: 3_STAR -synonym: "farnesane sesquiterpenoid" EXACT [ChEBI] -synonym: "farnesane sesquiterpenoids" RELATED [ChEBI] -is_a: CHEBI:26658 ! sesquiterpenoid -relationship: has_parent_hydride CHEBI:36756 ! farnesane - -[Term] -id: CHEBI:36834 -name: 3-hydroxy steroid -namespace: chebi_ontology -def: "Any hydroxy steroid carrying a hydroxy group at position 3." [] -subset: 3_STAR -synonym: "3-hydroxy steroids" RELATED [ChEBI] -is_a: CHEBI:35350 ! hydroxy steroid - -[Term] -id: CHEBI:36838 -name: 17-hydroxy steroid -namespace: chebi_ontology -def: "A hydroxy steroid carrying a hydroxy group at position 17." [] -subset: 3_STAR -synonym: "17-hydroxy steroids" RELATED [ChEBI] -is_a: CHEBI:35350 ! hydroxy steroid - -[Term] -id: CHEBI:36841 -name: 11-hydroxy steroid -namespace: chebi_ontology -subset: 3_STAR -synonym: "11-hydroxy steroids" RELATED [ChEBI] -is_a: CHEBI:35350 ! hydroxy steroid - -[Term] -id: CHEBI:36871 -name: inorganic radical -namespace: chebi_ontology -subset: 3_STAR -synonym: "inorganic radicals" RELATED [ChEBI] -is_a: CHEBI:24835 ! inorganic molecular entity -is_a: CHEBI:26519 ! radical - -[Term] -id: CHEBI:36873 -name: radical anion -namespace: chebi_ontology -subset: 3_STAR -synonym: "anion radical" RELATED [IUPAC] -synonym: "radical anion" EXACT IUPAC_NAME [IUPAC] -synonym: "radical anions" RELATED [ChEBI] -is_a: CHEBI:22563 ! anion -is_a: CHEBI:36875 ! radical ion - -[Term] -id: CHEBI:36875 -name: radical ion -namespace: chebi_ontology -def: "A radical that carries an electric charge." [] -subset: 3_STAR -synonym: "ion radical" RELATED [IUPAC] -synonym: "radical ion" EXACT IUPAC_NAME [IUPAC] -synonym: "radical ions" RELATED [IUPAC] -is_a: CHEBI:24870 ! ion -is_a: CHEBI:26519 ! radical - -[Term] -id: CHEBI:36876 -name: inorganic radical anion -namespace: chebi_ontology -subset: 3_STAR -synonym: "inorganic anion radical" RELATED [ChEBI] -synonym: "inorganic radical anions" RELATED [ChEBI] -is_a: CHEBI:36873 ! radical anion -is_a: CHEBI:36878 ! inorganic radical ion - -[Term] -id: CHEBI:36878 -name: inorganic radical ion -namespace: chebi_ontology -subset: 3_STAR -synonym: "inorganic ion radical" RELATED [ChEBI] -synonym: "inorganic radical ions" RELATED [ChEBI] -is_a: CHEBI:36871 ! inorganic radical -is_a: CHEBI:36875 ! radical ion - -[Term] -id: CHEBI:36885 -name: 20-oxo steroid -namespace: chebi_ontology -def: "An oxo steroid carrying an oxo group at position 20." [] -subset: 3_STAR -synonym: "20-oxo steroids" RELATED [ChEBI] -is_a: CHEBI:35789 ! oxo steroid - -[Term] -id: CHEBI:36887 -name: 18-oxo steroid -namespace: chebi_ontology -subset: 3_STAR -synonym: "18-oxo steroids" RELATED [ChEBI] -is_a: CHEBI:35789 ! oxo steroid - -[Term] -id: CHEBI:36902 -name: chalcogen hydride -namespace: chebi_ontology -subset: 3_STAR -synonym: "chalcogen hydride" EXACT [ChEBI] -synonym: "chalcogen hydrides" RELATED [ChEBI] -is_a: CHEBI:33242 ! inorganic hydride -is_a: CHEBI:33304 ! chalcogen molecular entity - -[Term] -id: CHEBI:36914 -name: inorganic ion -namespace: chebi_ontology -subset: 3_STAR -synonym: "inorganic ions" RELATED [ChEBI] -is_a: CHEBI:24835 ! inorganic molecular entity -is_a: CHEBI:24870 ! ion - -[Term] -id: CHEBI:36915 -name: inorganic cation -namespace: chebi_ontology -subset: 3_STAR -synonym: "inorganic cations" RELATED [ChEBI] -is_a: CHEBI:36914 ! inorganic ion -is_a: CHEBI:36916 ! cation - -[Term] -id: CHEBI:36916 -name: cation -namespace: chebi_ontology -alt_id: CHEBI:23058 -alt_id: CHEBI:3473 -def: "A monoatomic or polyatomic species having one or more elementary charges of the proton." [ANON:ANON] -subset: 3_STAR -synonym: "Cation" EXACT [KEGG_COMPOUND] -synonym: "Cation" EXACT [KEGG COMPOUND:] -synonym: "cation" EXACT IUPAC_NAME [IUPAC] -synonym: "cation" EXACT [ChEBI:] -synonym: "cation" EXACT [ChEBI] -synonym: "cation" EXACT IUPAC_NAME [IUPAC:] -synonym: "cationes" RELATED [ChEBI] -synonym: "cationes" RELATED [ChEBI:] -synonym: "cations" RELATED [ChEBI] -synonym: "cations" RELATED [ChEBI:] -synonym: "Kation" RELATED [ChEBI:] -synonym: "Kation" RELATED [ChEBI] -synonym: "Kationen" RELATED [ChEBI:] -synonym: "Kationen" RELATED [ChEBI] -xref: KEGG:C01373 -is_a: CHEBI:24870 ! ion - -[Term] -id: CHEBI:36961 -name: chalcocarbonic acid -namespace: chebi_ontology -subset: 3_STAR -synonym: "chalcocarbonic acid" EXACT [ChEBI] -synonym: "chalcocarbonic acids" EXACT IUPAC_NAME [IUPAC] -synonym: "chalcocarbonic acids" RELATED [ChEBI] -is_a: CHEBI:36962 ! organochalcogen compound - -[Term] -id: CHEBI:36962 -name: organochalcogen compound -namespace: chebi_ontology -def: "An organochalcogen compound is a compound containing at least one carbon-chalcogen bond." [ANON:ANON] -subset: 3_STAR -synonym: "organochalcogen compound" EXACT [ChEBI] -synonym: "organochalcogen compound" EXACT [ChEBI:] -synonym: "organochalcogen compounds" RELATED [ChEBI] -synonym: "organochalcogen compounds" RELATED [ChEBI:] -is_a: CHEBI:33285 ! heteroorganic entity -is_a: CHEBI:33304 ! chalcogen molecular entity - -[Term] -id: CHEBI:36963 -name: organooxygen compound -namespace: chebi_ontology -def: "An organochalcogen compound containing at least one carbon-oxygen bond." [ANON:ANON] -subset: 3_STAR -synonym: "organooxygen compound" EXACT [ChEBI:] -synonym: "organooxygen compound" EXACT [ChEBI] -synonym: "organooxygen compounds" RELATED [ChEBI] -synonym: "organooxygen compounds" RELATED [ChEBI:] -xref: PMID:17586126 {source="Europe PMC"} -is_a: CHEBI:25806 ! oxygen molecular entity -is_a: CHEBI:36962 ! organochalcogen compound - -[Term] -id: CHEBI:37022 -name: amino-acid anion -namespace: chebi_ontology -subset: 3_STAR -synonym: "amino acid anions" RELATED [ChEBI] -synonym: "amino-acid anion" EXACT [ChEBI] -synonym: "amino-acid anions" RELATED [ChEBI] -is_a: CHEBI:29067 ! carboxylic acid anion -is_a: CHEBI:35352 ! organonitrogen compound -relationship: is_conjugate_base_of CHEBI:33709 ! amino acid - -[Term] -id: CHEBI:37163 -name: glucan -namespace: chebi_ontology -alt_id: CHEBI:24255 -alt_id: CHEBI:5392 -def: "A polysaccharide composed of glucose residues." [] -subset: 3_STAR -synonym: "Glucan" EXACT [KEGG_COMPOUND] -synonym: "glucan" EXACT IUPAC_NAME [IUPAC] -synonym: "glucans" RELATED [ChEBI] -xref: CAS:9037-91-6 {source="ChemIDplus"} -xref: KEGG:C01379 -is_a: CHEBI:37164 ! homopolysaccharide -property_value: http://purl.obolibrary.org/obo/chebi/formula "C12H22O11(C6H10O5)n" xsd:string - -[Term] -id: CHEBI:37164 -name: homopolysaccharide -namespace: chebi_ontology -def: "Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'." [] -subset: 3_STAR -synonym: "homoglycan" RELATED [IUPAC] -synonym: "homopolysaccharide" EXACT IUPAC_NAME [IUPAC] -synonym: "homopolysaccharides" RELATED [ChEBI] -is_a: CHEBI:18154 ! polysaccharide - -[Term] -id: CHEBI:37175 -name: organic hydride -namespace: chebi_ontology -subset: 3_STAR -synonym: "organic hydrides" RELATED [ChEBI] -is_a: CHEBI:33692 ! hydrides - -[Term] -id: CHEBI:37176 -name: mononuclear parent hydride -namespace: chebi_ontology -subset: 3_STAR -synonym: "mononuclear hydride" RELATED [ChEBI] -synonym: "mononuclear hydrides" RELATED [IUPAC] -synonym: "mononuclear parent hydrides" EXACT IUPAC_NAME [IUPAC] -is_a: CHEBI:33692 ! hydrides - -[Term] -id: CHEBI:37246 -name: elemental sodium -namespace: chebi_ontology -subset: 3_STAR -is_a: CHEBI:26712 ! sodium molecular entity - -[Term] -id: CHEBI:37395 -name: mucopolysaccharide -namespace: chebi_ontology -alt_id: CHEBI:25425 -alt_id: CHEBI:7011 -def: "Any of the group of polysaccharides composed of alternating units from uronic acids and glycosamines, and commonly partially esterified with sulfuric acid." [] -subset: 3_STAR -synonym: "mucopolisacarido" RELATED [ChEBI] -synonym: "mucopolisacaridos" RELATED [IUPAC] -synonym: "Mucopolysaccharid" RELATED [ChEBI] -synonym: "Mucopolysaccharide" EXACT [KEGG_COMPOUND] -synonym: "mucopolysaccharides" EXACT IUPAC_NAME [IUPAC] -synonym: "Mukopolysaccharid" RELATED [ChEBI] -xref: KEGG:C05114 -is_a: CHEBI:18085 ! glycosaminoglycan - -[Term] -id: CHEBI:37396 -name: proteoglycan -namespace: chebi_ontology -alt_id: CHEBI:26351 -alt_id: CHEBI:8582 -def: "A glycoprotein in which the carbohydrate units are polysaccharides that contain amino sugars. The protein is glycosylated by one or more (up to about 100) glycosaminoglycans." [] -subset: 3_STAR -synonym: "Proteoglycan" EXACT [KEGG_COMPOUND] -synonym: "proteoglycans" EXACT IUPAC_NAME [IUPAC] -xref: KEGG:C00866 -is_a: CHEBI:17089 ! glycoprotein -is_a: CHEBI:65212 ! polysaccharide derivative - -[Term] -id: CHEBI:37397 -name: chondroitin sulfate -namespace: chebi_ontology -alt_id: CHEBI:23224 -alt_id: CHEBI:3676 -def: "Any of a class of 10--60 kDa glycosaminoglycan sulfates, widely distributed in cartilage and other mammalian connective tissues." [] -subset: 3_STAR -synonym: "chondroitin polysulfate" RELATED [ChemIDplus] -synonym: "Chondroitin sulfate" EXACT [KEGG_COMPOUND] -synonym: "chondroitin sulfates" RELATED [ChemIDplus] -synonym: "chondroitin sulfuric acid" RELATED [ChemIDplus] -synonym: "chondroitin sulphate" RELATED [ChemIDplus] -synonym: "Chondroitinsulfat" RELATED [ChEBI] -xref: CAS:9007-28-7 {source="ChemIDplus"} -xref: CAS:9007-28-7 {source="KEGG COMPOUND"} -xref: KEGG:C00607 -xref: PMID:11514091 {source="Europe PMC"} -xref: PMID:7538297 {source="Europe PMC"} -is_a: CHEBI:35722 ! sulfated glycosaminoglycan -is_a: CHEBI:37395 ! mucopolysaccharide -relationship: has_functional_parent CHEBI:16137 ! chondroitin D-glucuronate - -[Term] -id: CHEBI:37527 -name: acid -namespace: chebi_ontology -alt_id: CHEBI:13800 -alt_id: CHEBI:13801 -alt_id: CHEBI:22209 -alt_id: CHEBI:2426 -def: "An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid)." [] -subset: 3_STAR -synonym: "Acid" EXACT [KEGG_COMPOUND] -synonym: "acid" EXACT IUPAC_NAME [IUPAC] -synonym: "acide" RELATED [IUPAC] -synonym: "acido" RELATED [ChEBI] -synonym: "acids" RELATED [ChEBI] -synonym: "Saeure" RELATED [ChEBI] -synonym: "Saeuren" RELATED [ChEBI] -xref: KEGG:C00174 -is_a: CHEBI:51086 ! chemical role - -[Term] -id: CHEBI:37577 -name: heteroatomic molecular entity -namespace: chebi_ontology -def: "A molecular entity consisting of two or more chemical elements." [ANON:ANON] -subset: 3_STAR -synonym: "chemical compound" RELATED [ChEBI] -synonym: "chemical compound" RELATED [ChEBI:] -synonym: "heteroatomic molecular entities" RELATED [ChEBI] -synonym: "heteroatomic molecular entities" RELATED [ChEBI:] -is_a: CHEBI:36357 ! polyatomic entity - -[Term] -id: CHEBI:37622 -name: carboxamide -namespace: chebi_ontology -alt_id: CHEBI:35354 -alt_id: CHEBI:35355 -def: "An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom." [ANON:ANON] -subset: 3_STAR -synonym: "[*]C(=O)N([*])[*]" RELATED SMILES [ChEBI:] -synonym: "carboxamides" EXACT IUPAC_NAME [IUPAC:] -synonym: "carboxamides" EXACT IUPAC_NAME [IUPAC] -synonym: "carboxamides" RELATED [ChEBI] -synonym: "carboxamides" RELATED [ChEBI:] -synonym: "primary carboxamide" RELATED [ChEBI] -synonym: "primary carboxamide" RELATED [ChEBI:] -is_a: CHEBI:33256 ! primary amide -is_a: CHEBI:35352 ! organonitrogen compound -is_a: CHEBI:36963 ! organooxygen compound -relationship: has_part CHEBI:23004 ! carbamoyl group -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CNOR3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "42.01680" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "41.99799" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]C(=O)N([*])[*]" xsd:string - -[Term] -id: CHEBI:37826 -name: sulfuric acid derivative -namespace: chebi_ontology -subset: 3_STAR -synonym: "sulfuric acid derivative" EXACT [ChEBI] -synonym: "sulfuric acid derivatives" RELATED [ChEBI] -is_a: CHEBI:33424 ! sulfur oxoacid derivative -relationship: has_functional_parent CHEBI:26836 ! sulfuric acid - -[Term] -id: CHEBI:37838 -name: carboacyl group -namespace: chebi_ontology -def: "A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid." [] -subset: 3_STAR -synonym: "carboacyl groups" EXACT IUPAC_NAME [IUPAC] -synonym: "carboxylic acyl group" EXACT IUPAC_NAME [IUPAC] -synonym: "carboxylic acyl groups" RELATED [IUPAC] -is_a: CHEBI:22221 ! acyl group -relationship: is_substituent_group_from CHEBI:33575 ! carboxylic acid - -[Term] -id: CHEBI:37886 -name: adrenergic agonist -namespace: chebi_ontology -def: "An agent that selectively binds to and activates adrenergic receptors." [] -subset: 3_STAR -synonym: "adrenergic agonists" RELATED [ChEBI] -synonym: "adrenergic receptor agonist" RELATED [ChEBI] -synonym: "adrenoceptor agonists" RELATED [IUPHAR] -synonym: "adrenomimetic" RELATED [ChEBI] -synonym: "adrenomimetics" RELATED [ChEBI] -is_a: CHEBI:37962 ! adrenergic agent - -[Term] -id: CHEBI:37962 -name: adrenergic agent -namespace: chebi_ontology -def: "Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter." [] -subset: 3_STAR -synonym: "adrenergic agents" RELATED [ChEBI] -synonym: "adrenergic drug" RELATED [ChEBI] -synonym: "adrenergic drugs" RELATED [ChEBI] -synonym: "adrenergic neuron agents" RELATED [ChEBI] -synonym: "adrenergics" RELATED [ChEBI] -is_a: CHEBI:35942 ! neurotransmitter agent - -[Term] -id: CHEBI:38077 -name: polypyrrole -namespace: chebi_ontology -def: "A compound composed of two or more pyrrole units." [] -subset: 3_STAR -synonym: "poly(pyrrole)s" RELATED [ChEBI] -synonym: "polypyrroles" RELATED [ChEBI] -synonym: "PPys" RELATED [ChEBI] -xref: Beilstein:8538310 {source="Beilstein"} -is_a: CHEBI:38101 ! organonitrogen heterocyclic compound - -[Term] -id: CHEBI:38101 -name: organonitrogen heterocyclic compound -namespace: chebi_ontology -def: "Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms." [ANON:ANON] -subset: 3_STAR -synonym: "heterocyclic organonitrogen compounds" RELATED [ChEBI:] -synonym: "heterocyclic organonitrogen compounds" RELATED [ChEBI] -synonym: "organonitrogen heterocyclic compounds" RELATED [ChEBI] -synonym: "organonitrogen heterocyclic compounds" RELATED [ChEBI:] -is_a: CHEBI:24532 ! organic heterocyclic compound -is_a: CHEBI:35352 ! organonitrogen compound - -[Term] -id: CHEBI:38147 -name: cardiotonic drug -namespace: chebi_ontology -def: "A drug that has a strengthening effect on the heart or that can increase cardiac output." [] -subset: 3_STAR -synonym: "cardiotonic drugs" RELATED [ChEBI] -is_a: CHEBI:35554 ! cardiovascular drug - -[Term] -id: CHEBI:38166 -name: organic heteropolycyclic compound -namespace: chebi_ontology -alt_id: CHEBI:25429 -alt_id: CHEBI:38075 -subset: 3_STAR -synonym: "organic heteropolycyclic compounds" RELATED [ChEBI] -is_a: CHEBI:24532 ! organic heterocyclic compound -is_a: CHEBI:33671 ! heteropolycyclic compound - -[Term] -id: CHEBI:38179 -name: monocyclic heteroarene -namespace: chebi_ontology -subset: 3_STAR -synonym: "monocyclic heteroarenes" RELATED [ChEBI] -is_a: CHEBI:33833 ! heteroarene - -[Term] -id: CHEBI:38180 -name: polycyclic heteroarene -namespace: chebi_ontology -subset: 3_STAR -synonym: "polycyclic heteroarenes" RELATED [ChEBI] -synonym: "polycyclic heteroarenes" RELATED [ChEBI:] -is_a: CHEBI:33833 ! heteroarene - -[Term] -id: CHEBI:38323 -name: cholinergic drug -namespace: chebi_ontology -def: "Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons." [] -subset: 3_STAR -synonym: "cholinergic agent" RELATED [ChEBI] -synonym: "cholinergic drugs" RELATED [ChEBI] -synonym: "cholinomimetic" RELATED [ChEBI] -is_a: CHEBI:35942 ! neurotransmitter agent - -[Term] -id: CHEBI:38324 -name: cholinergic agonist -namespace: chebi_ontology -def: "Any drug that binds to and activates cholinergic receptors." [] -subset: 3_STAR -synonym: "acetylcholine agonist" RELATED [ChEBI] -synonym: "acetylcholine agonists" RELATED [ChEBI] -synonym: "acetylcholine receptor agonist" RELATED [IUPHAR] -synonym: "cholinergic agonists" RELATED [ChEBI] -synonym: "cholinomimetic" RELATED [ChEBI] -synonym: "cholinomimetics" RELATED [ChEBI] -is_a: CHEBI:38323 ! cholinergic drug - -[Term] -id: CHEBI:38325 -name: muscarinic agonist -namespace: chebi_ontology -def: "Any drug that binds to and activates a muscarinic cholinergic receptor." [] -subset: 3_STAR -synonym: "muscarinic acetylcholine receptor agonist" RELATED [ChEBI] -synonym: "muscarinic agonists" RELATED [ChEBI] -synonym: "muscarinic cholinergic agonist" RELATED [ChEBI] -synonym: "muscarinic cholinergic agonists" RELATED [ChEBI] -is_a: CHEBI:38324 ! cholinergic agonist - -[Term] -id: CHEBI:38560 -name: simple protein -namespace: chebi_ontology -subset: 3_STAR -synonym: "simple proteins" RELATED [ChEBI] -is_a: CHEBI:36080 ! protein -is_a: PR:000000001 ! protein - -[Term] -id: CHEBI:38631 -name: aminoalkylindole -namespace: chebi_ontology -alt_id: CHEBI:22503 -alt_id: CHEBI:24792 -subset: 3_STAR -synonym: "aminoalkylindoles" RELATED [ChEBI] -is_a: CHEBI:24828 ! indoles - -[Term] -id: CHEBI:38700 -name: organic sodium salt -namespace: chebi_ontology -subset: 3_STAR -synonym: "organic sodium salt" EXACT [ChEBI] -synonym: "organic sodium salts" RELATED [ChEBI] -is_a: CHEBI:24868 ! organic salt -is_a: CHEBI:26714 ! sodium salt - -[Term] -id: CHEBI:38716 -name: carboxylic acid dianion -namespace: chebi_ontology -def: "Any dianion containing at least one carboxy group." [] -subset: 3_STAR -synonym: "carboxylic acid dianion" EXACT [ChEBI] -synonym: "carboxylic acid dianions" RELATED [ChEBI] -is_a: CHEBI:29067 ! carboxylic acid anion - -[Term] -id: CHEBI:3892 -name: corticotropin -namespace: chebi_ontology -def: "A polypeptide hormone produced and secreted by the pituitary gland comprising 39 amino acid residues coupled in a linear sequence. The N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Corticotropin stimulates the cortex of the adrenal gland and boosts the synthesis of corticosteroids, mainly glucocorticoids but also sex steroids (androgens). It is used in the treatment of certain neurological disorders such as infantile spasms and multiple sclerosis, and diagnostically to investigate adrenocortical insufficiency." [] -subset: 3_STAR -synonym: "ACTH" RELATED [KEGG_COMPOUND] -synonym: "Adrenocorticotropic hormone" RELATED [KEGG_COMPOUND] -synonym: "adrenocorticotropin" RELATED [ChemIDplus] -synonym: "corticotrofina" RELATED INN [ChemIDplus] -synonym: "corticotrophine" RELATED INN [ChemIDplus] -synonym: "corticotrophinum" RELATED INN [ChemIDplus] -synonym: "Corticotropin" EXACT [KEGG_COMPOUND] -synonym: "corticotropin" RELATED INN [ChemIDplus] -synonym: "cortrophin" RELATED [ChemIDplus] -synonym: "L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-prolyl-L-alpha-aspartylglycyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alpha-glutamyl-L-seryl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-prolyl-L-leucyl-L-alpha-glutamyl-L-phenylalanine" EXACT IUPAC_NAME [IUPAC] -synonym: "SYSMEHFRWGKPVGKKRRPVKVYPDGAEDQLAEAFPLEF" RELATED [DrugBank] -xref: CAS:9002-60-2 {source="ChemIDplus"} -xref: CAS:9002-60-2 {source="KEGG COMPOUND"} -xref: Drug_Central:4931 {source="DrugCentral"} -xref: DrugBank:DB01285 -xref: KEGG:C02017 -xref: KEGG:D00146 -is_a: CHEBI:15841 ! polypeptide -is_a: CHEBI:25905 ! peptide hormone -is_a: CHEBI:33694 ! biomacromolecule -relationship: RO:0000087 CHEBI:33295 ! has role diagnostic agent -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C207H308N56O58S" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C207H308N56O58S/c1-108(2)89-140(186(302)240-135(69-74-163(279)280)182(298)254-149(204(320)321)94-117-43-20-15-21-44-117)250-193(309)152-54-35-86-262(152)202(318)147(92-116-41-18-14-19-42-116)252-171(287)114(11)230-175(291)132(66-71-160(273)274)234-170(286)113(10)231-191(307)150(105-265)255-183(299)136(70-75-164(281)282)241-190(306)146(98-165(283)284)249-180(296)133(67-72-161(275)276)235-169(285)112(9)229-157(270)101-225-174(290)145(97-156(213)269)251-194(310)153-55-36-87-263(153)203(319)148(93-119-60-64-123(268)65-61-119)253-199(315)167(110(5)6)257-185(301)129(49-26-30-79-210)243-198(314)168(111(7)8)259-196(312)155-57-38-85-261(155)201(317)139(53-34-83-223-207(218)219)244-178(294)130(51-32-81-221-205(214)215)237-177(293)128(48-25-29-78-209)236-176(292)127(47-24-28-77-208)232-158(271)103-227-197(313)166(109(3)4)258-195(311)154-56-37-84-260(154)200(316)138(50-27-31-80-211)233-159(272)102-226-173(289)143(95-120-99-224-126-46-23-22-45-124(120)126)247-179(295)131(52-33-82-222-206(216)217)238-187(303)142(90-115-39-16-13-17-40-115)246-189(305)144(96-121-100-220-107-228-121)248-181(297)134(68-73-162(277)278)239-184(300)137(76-88-322-12)242-192(308)151(106-266)256-188(304)141(245-172(288)125(212)104-264)91-118-58-62-122(267)63-59-118/h13-23,39-46,58-65,99-100,107-114,125,127-155,166-168,224,264-268H,24-38,47-57,66-98,101-106,208-212H2,1-12H3,(H2,213,269)(H,220,228)(H,225,290)(H,226,289)(H,227,313)(H,229,270)(H,230,291)(H,231,307)(H,232,271)(H,233,272)(H,234,286)(H,235,285)(H,236,292)(H,237,293)(H,238,303)(H,239,300)(H,240,302)(H,241,306)(H,242,308)(H,243,314)(H,244,294)(H,245,288)(H,246,305)(H,247,295)(H,248,297)(H,249,296)(H,250,309)(H,251,310)(H,252,287)(H,253,315)(H,254,298)(H,255,299)(H,256,304)(H,257,301)(H,258,311)(H,259,312)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,320,321)(H4,214,215,221)(H4,216,217,222)(H4,218,219,223)/t112-,113-,114-,125-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,154-,155-,166-,167-,168-/m0/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "IDLFZVILOHSSID-OVLDLUHVSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "4541.06600" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "4538.25937" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O" xsd:string - -[Term] -id: CHEBI:38958 -name: indole alkaloid -namespace: chebi_ontology -alt_id: CHEBI:24795 -alt_id: CHEBI:5901 -def: "An alkaloid containing an indole skeleton." [] -subset: 3_STAR -synonym: "Indole alkaloid" EXACT [KEGG_COMPOUND] -synonym: "indole alkaloids" RELATED [ChEBI] -xref: KEGG:C06073 -xref: Wikipedia:Indole_alkaloid -is_a: CHEBI:22315 ! alkaloid -relationship: has_part CHEBI:73398 ! indole skeleton - -[Term] -id: CHEBI:39015 -name: apolipoprotein -namespace: chebi_ontology -def: "Protein component on the surface of lipoprotein." [] -subset: 3_STAR -synonym: "apolipoproteins" RELATED [ChEBI] -is_a: CHEBI:13850 ! apoprotein - -[Term] -id: CHEBI:39022 -name: inclusion compound -namespace: chebi_ontology -def: "A complex in which one component (the host) forms a cavity or, in the case of a crystal, a crystal lattice containing spaces in the shape of long tunnels or channels in which molecular entities of a second chemical species (the guest) are located. There is no covalent bonding between guest and host, the attraction being generally due to van der Waals forces." [] -subset: 3_STAR -synonym: "compose d'inclusion" RELATED [IUPAC] -synonym: "compuesto de inclusion" RELATED [IUPAC] -synonym: "compuestos de inclusion" RELATED [IUPAC] -synonym: "inclusion complex" RELATED [IUPAC] -synonym: "inclusion compound" EXACT IUPAC_NAME [IUPAC] -synonym: "inclusion compounds" RELATED [ChEBI] -is_a: CHEBI:50967 ! non-covalently-bound molecular entity - -[Term] -id: CHEBI:39024 -name: clathrate compound -namespace: chebi_ontology -def: "Inclusion compound in which the guest molecule is in a cage formed by the host molecule or by a lattice of host molecules." [] -subset: 3_STAR -synonym: "cage compound" RELATED [IUPAC] -synonym: "Clathrat" RELATED [ChEBI] -synonym: "clathrate" RELATED [IUPAC] -synonym: "clathrate compounds" RELATED [ChEBI] -synonym: "clathrates" EXACT IUPAC_NAME [IUPAC] -synonym: "Clathratverbindung" RELATED [ChEBI] -synonym: "clatrato" RELATED [IUPAC] -synonym: "clatratos" RELATED [IUPAC] -synonym: "compuesto de clatrato" RELATED [ChEBI] -synonym: "Klathrat" RELATED [ChEBI] -synonym: "Klathratverbindung" RELATED [ChEBI] -is_a: CHEBI:39022 ! inclusion compound - -[Term] -id: CHEBI:39123 -name: calcium cation -namespace: chebi_ontology -subset: 3_STAR -synonym: "calcium cation" EXACT [ChEBI] -synonym: "calcium cations" RELATED [ChEBI] -is_a: CHEBI:33513 ! alkaline earth cation -is_a: CHEBI:39124 ! calcium ion -property_value: http://purl.obolibrary.org/obo/chebi/formula "Ca" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "40.078" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "39.96259" xsd:string - -[Term] -id: CHEBI:39124 -name: calcium ion -namespace: chebi_ontology -subset: 3_STAR -synonym: "calcium ion" EXACT [ChEBI] -synonym: "calcium ions" RELATED [ChEBI] -is_a: CHEBI:25213 ! metal cation -is_a: CHEBI:35155 ! elemental calcium -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "Ca" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "40.078" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "39.96259" xsd:string - -[Term] -id: CHEBI:39141 -name: Bronsted acid -namespace: chebi_ontology -def: "A molecular entity capable of donating a hydron to an acceptor (Bronsted base)." [] -subset: 3_STAR -synonym: "acide de Bronsted" RELATED [IUPAC] -synonym: "Bronsted acid" EXACT IUPAC_NAME [IUPAC] -synonym: "Bronsted-Saeure" RELATED [ChEBI] -synonym: "donneur d'hydron" RELATED [IUPAC] -synonym: "hydron donor" RELATED [IUPAC] -is_a: CHEBI:17891 ! donor -is_a: CHEBI:37527 ! acid - -[Term] -id: CHEBI:39142 -name: Bronsted base -namespace: chebi_ontology -def: "A molecular entity capable of accepting a hydron from a donor (Bronsted acid)." [] -subset: 3_STAR -synonym: "accepteur d'hydron" RELATED [IUPAC] -synonym: "base de Bronsted" RELATED [IUPAC] -synonym: "Bronsted base" EXACT IUPAC_NAME [IUPAC] -synonym: "Bronsted-Base" RELATED [ChEBI] -synonym: "hydron acceptor" RELATED [IUPAC] -is_a: CHEBI:15339 ! acceptor -is_a: CHEBI:22695 ! base - -[Term] -id: CHEBI:39144 -name: Lewis base -namespace: chebi_ontology -def: "A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct." [] -subset: 3_STAR -synonym: "base de Lewis" RELATED [IUPAC] -synonym: "donneur d'une paire d'electrons" RELATED [ChEBI] -synonym: "electron donor" RELATED [ChEBI] -synonym: "Lewis base" EXACT IUPAC_NAME [IUPAC] -synonym: "Lewis-Base" RELATED [ChEBI] -is_a: CHEBI:17891 ! donor -is_a: CHEBI:22695 ! base - -[Term] -id: CHEBI:39418 -name: straight-chain saturated fatty acid -namespace: chebi_ontology -def: "Any saturated fatty acid lacking a carbon side-chain." [ANON:ANON] -def: "Any saturated fatty acid lacking a side-chain." [] -subset: 3_STAR -synonym: "straight-chain saturated fatty acid" EXACT [ChEBI:] -synonym: "straight-chain saturated fatty acid" EXACT [ChEBI] -synonym: "straight-chain saturated fatty acids" RELATED [ChEBI:] -synonym: "straight-chain saturated fatty acids" RELATED [ChEBI] -xref: PMID:15644336 {source="Europe PMC"} -is_a: CHEBI:26607 ! saturated fatty acid -is_a: CHEBI:59202 ! straight-chain fatty acid -relationship: is_conjugate_acid_of CHEBI:58954 ! straight-chain saturated fatty acid anion - -[Term] -id: CHEBI:39745 -name: dihydrogenphosphate -namespace: chebi_ontology -alt_id: CHEBI:29137 -alt_id: CHEBI:39739 -def: "A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated." [] -subset: 3_STAR -synonym: "[PO2(OH)2](-)" RELATED [IUPAC] -synonym: "dihydrogen(tetraoxidophosphate)(1-)" EXACT IUPAC_NAME [IUPAC] -synonym: "dihydrogenphosphate" EXACT IUPAC_NAME [IUPAC] -synonym: "DIHYDROGENPHOSPHATE ION" RELATED [PDBeChem] -synonym: "dihydrogentetraoxophosphate(1-)" EXACT IUPAC_NAME [IUPAC] -synonym: "dihydrogentetraoxophosphate(V)" EXACT IUPAC_NAME [IUPAC] -synonym: "dihydroxidodioxidophosphate(1-)" EXACT IUPAC_NAME [IUPAC] -synonym: "H2PO4(-)" RELATED [IUPAC] -xref: DrugBank:DB02831 -xref: Gmelin:1999 {source="Gmelin"} -xref: PDBeChem:2HP -is_a: CHEBI:35780 ! phosphate ion -is_a: CHEBI:79389 ! monovalent inorganic anion -relationship: is_conjugate_acid_of CHEBI:43474 ! hydrogenphosphate -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "H2O4P" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-M" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "96.98724" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "96.96962" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OP([O-])(=O)O[H]" xsd:string - -[Term] -id: CHEBI:3992 -name: cyclic ketone -namespace: chebi_ontology -subset: 3_STAR -synonym: "Cyclic ketone" EXACT [KEGG_COMPOUND] -synonym: "cyclic ketones" EXACT IUPAC_NAME [IUPAC] -xref: KEGG:C02019 -is_a: CHEBI:17087 ! ketone - -[Term] -id: CHEBI:41609 -name: carbonate -namespace: chebi_ontology -alt_id: CHEBI:29201 -alt_id: CHEBI:41605 -subset: 3_STAR -synonym: "[CO3](2-)" RELATED [IUPAC] -synonym: "carbonate" EXACT [IUPAC] -synonym: "CARBONATE ION" RELATED [PDBeChem] -synonym: "CO3(2-)" RELATED [ChEBI] -synonym: "Karbonat" RELATED [ChEBI] -synonym: "trioxidocarbonate(2-)" EXACT IUPAC_NAME [IUPAC] -xref: Beilstein:3600898 {source="Beilstein"} -xref: CAS:3812-32-6 {source="ChemIDplus"} -xref: Gmelin:1559 {source="Gmelin"} -xref: PDBeChem:CO3 -is_a: CHEBI:35604 ! carbon oxoanion -relationship: is_conjugate_base_of CHEBI:17544 ! hydrogencarbonate -property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CO3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-L" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "60.00890" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "59.98584" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([O-])=O" xsd:string - -[Term] -id: CHEBI:42485 -name: formyl group -namespace: chebi_ontology -alt_id: CHEBI:24089 -alt_id: CHEBI:42480 -subset: 3_STAR -synonym: "-CH(O)" RELATED [IUPAC] -synonym: "-CHO" RELATED [IUPAC] -synonym: "aldehyde group" EXACT IUPAC_NAME [IUPAC] -synonym: "carbaldehyde" EXACT IUPAC_NAME [IUPAC] -synonym: "Fo" RELATED [CBN] -synonym: "formyl" EXACT IUPAC_NAME [IUPAC] -synonym: "FORMYL GROUP" EXACT [PDBeChem] -synonym: "H-CO-" RELATED [IUPAC] -synonym: "methanoyl" RELATED [IUPAC] -xref: PDBeChem:FOR -is_a: CHEBI:27207 ! univalent carboacyl group -relationship: is_substituent_group_from CHEBI:30751 ! formic acid -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "29.01804" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "29.00274" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]C(*)=O" xsd:string - -[Term] -id: CHEBI:43176 -name: hydroxy group -namespace: chebi_ontology -alt_id: CHEBI:24706 -alt_id: CHEBI:43171 -subset: 3_STAR -synonym: "-OH" RELATED [IUPAC] -synonym: "hydroxy" EXACT IUPAC_NAME [IUPAC] -synonym: "HYDROXY GROUP" EXACT [PDBeChem] -synonym: "hydroxy group" EXACT [UniProt] -synonym: "hydroxyl" RELATED [ChEBI] -synonym: "hydroxyl group" RELATED [ChEBI] -xref: PDBeChem:OH -is_a: CHEBI:33246 ! inorganic group -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "HO" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "17.00734" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "17.00274" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "*O[H]" xsd:string - -[Term] -id: CHEBI:43474 -name: hydrogenphosphate -namespace: chebi_ontology -alt_id: CHEBI:29139 -alt_id: CHEBI:43470 -def: "A phosphate ion that is the conjugate base of dihydrogenphosphate." [] -subset: 3_STAR -synonym: "[P(OH)O3](2-)" RELATED [MolBase] -synonym: "[PO3(OH)](2-)" RELATED [IUPAC] -synonym: "HPO4(2-)" RELATED [IUPAC] -synonym: "hydrogen phosphate" RELATED [ChEBI] -synonym: "hydrogen(tetraoxidophosphate)(2-)" EXACT IUPAC_NAME [IUPAC] -synonym: "hydrogenphosphate" EXACT IUPAC_NAME [IUPAC] -synonym: "HYDROGENPHOSPHATE ION" RELATED [PDBeChem] -synonym: "hydrogentetraoxophosphate(2-)" EXACT IUPAC_NAME [IUPAC] -synonym: "hydrogentetraoxophosphate(V)" EXACT IUPAC_NAME [IUPAC] -synonym: "hydroxidotrioxidophosphate(2-)" EXACT IUPAC_NAME [IUPAC] -synonym: "INORGANIC PHOSPHATE GROUP" RELATED [PDBeChem] -synonym: "phosphate" RELATED [UniProt] -xref: Gmelin:1998 {source="Gmelin"} -xref: MolBase:1628 -xref: PDBeChem:PI -xref: PDBeChem:PO4 -is_a: CHEBI:35780 ! phosphate ion -is_a: CHEBI:79388 ! divalent inorganic anion -relationship: is_conjugate_acid_of CHEBI:18367 ! phosphate(3-) -relationship: is_conjugate_base_of CHEBI:39745 ! dihydrogenphosphate -relationship: RO:0000087 CHEBI:23357 ! has role cofactor -relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "HO4P" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-L" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "95.97930" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.96234" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "OP([O-])([O-])=O" xsd:string - -[Term] -id: CHEBI:45696 -name: hydrogensulfate -namespace: chebi_ontology -alt_id: CHEBI:29199 -alt_id: CHEBI:45693 -subset: 3_STAR -synonym: "[SO3(OH)](-)" RELATED [IUPAC] -synonym: "HSO4(-)" RELATED [IUPAC] -synonym: "HYDROGEN SULFATE" RELATED [PDBeChem] -synonym: "hydrogen(tetraoxidosulfate)(1-)" EXACT IUPAC_NAME [IUPAC] -synonym: "hydrogensulfate" EXACT [IUPAC] -synonym: "hydrogensulfate(1-)" EXACT IUPAC_NAME [IUPAC] -synonym: "hydrogentetraoxosulfate(1-)" EXACT IUPAC_NAME [IUPAC] -synonym: "hydrogentetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC] -synonym: "hydroxidotrioxidosulfate(1-)" EXACT IUPAC_NAME [IUPAC] -xref: Gmelin:2121 {source="Gmelin"} -is_a: CHEBI:33482 ! sulfur oxoanion -relationship: is_conjugate_acid_of CHEBI:16189 ! sulfate -relationship: is_conjugate_base_of CHEBI:26836 ! sulfuric acid -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "HO4S" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QAOWNCQODCNURD-UHFFFAOYSA-M" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "97.07154" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "96.96010" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OS([O-])(=O)=O" xsd:string - -[Term] -id: CHEBI:46629 -name: oxo group -namespace: chebi_ontology -alt_id: CHEBI:29353 -alt_id: CHEBI:44607 -subset: 3_STAR -synonym: "=O" RELATED [IUPAC] -synonym: "oxo" EXACT IUPAC_NAME [IUPAC] -synonym: "OXO GROUP" EXACT [PDBeChem] -xref: PDBeChem:O -is_a: CHEBI:33246 ! inorganic group -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "15.99940" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.99491" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=*" xsd:string - -[Term] -id: CHEBI:46662 -name: mineral -namespace: chebi_ontology -def: "In general, a mineral is a chemical substance that is normally crystalline formed and has been formed as a result of geological processes. The term also includes metamict substances (naturally occurring, formerly crystalline substances whose crystallinity has been destroyed by ionising radiation) and can include naturally occurring amorphous substances that have never been crystalline ('mineraloids') such as georgite and calciouranoite as well as substances formed by the action of geological processes on bigenic compounds ('biogenic minerals')." [] -subset: 3_STAR -synonym: "mineral" EXACT [ChEBI] -synonym: "Minerale" RELATED [ChEBI] -synonym: "minerales" RELATED [ChEBI] -synonym: "minerals" RELATED [ChEBI] -synonym: "mineraux" RELATED [ChEBI] -xref: Wikipedia:Mineral -is_a: CHEBI:59999 ! chemical substance - -[Term] -id: CHEBI:46723 -name: phosphate mineral -namespace: chebi_ontology -subset: 3_STAR -synonym: "phosphate minerals" RELATED [ChEBI] -is_a: CHEBI:46662 ! mineral - -[Term] -id: CHEBI:46787 -name: solvent -namespace: chebi_ontology -def: "A liquid that can dissolve other substances (solutes) without any change in their chemical composition." [] -subset: 3_STAR -synonym: "Loesungsmittel" RELATED [ChEBI] -synonym: "solvant" RELATED [ChEBI] -synonym: "solvents" RELATED [ChEBI] -xref: Wikipedia:Solvent -is_a: CHEBI:33232 ! application -is_a: CHEBI:51086 ! chemical role - -[Term] -id: CHEBI:46883 -name: carboxy group -namespace: chebi_ontology -alt_id: CHEBI:23025 -alt_id: CHEBI:41420 -subset: 3_STAR -synonym: "-C(O)OH" RELATED [IUPAC] -synonym: "-CO2H" RELATED [ChEBI] -synonym: "-COOH" RELATED [IUPAC] -synonym: "carboxy" EXACT IUPAC_NAME [IUPAC] -synonym: "CARBOXY GROUP" EXACT [PDBeChem] -synonym: "carboxyl group" RELATED [ChEBI] -xref: PDBeChem:FMT -is_a: CHEBI:33249 ! organyl group -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "45.01744" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.99765" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "*C(=O)O" xsd:string - -[Term] -id: CHEBI:47622 -name: acetate ester -namespace: chebi_ontology -alt_id: CHEBI:13244 -alt_id: CHEBI:13799 -alt_id: CHEBI:22189 -alt_id: CHEBI:2406 -def: "Any carboxylic ester where the carboxylic acid component is acetic acid." [ANON:ANON] -subset: 3_STAR -synonym: "acetate" RELATED [ChEBI] -synonym: "acetate" RELATED [ChEBI:] -synonym: "acetate esters" RELATED [ChEBI:] -synonym: "acetate esters" RELATED [ChEBI] -synonym: "acetates" RELATED [ChEBI:] -synonym: "acetates" RELATED [ChEBI] -synonym: "Acetic ester" RELATED [KEGG COMPOUND:] -synonym: "Acetic ester" RELATED [KEGG_COMPOUND] -synonym: "Acetyl ester" RELATED [KEGG_COMPOUND] -synonym: "Acetyl ester" RELATED [KEGG COMPOUND:] -synonym: "acetyl ester" RELATED [UniProt:] -synonym: "acetyl esters" RELATED [ChEBI] -synonym: "acetyl esters" RELATED [ChEBI:] -synonym: "an acetyl ester" RELATED [UniProt] -synonym: "C2H3O2R" RELATED FORMULA [KEGG COMPOUND:] -xref: KEGG:C01883 -xref: Wikipedia:Acetate#Esters -is_a: CHEBI:33308 ! carboxylic ester -relationship: has_functional_parent CHEBI:15366 ! acetic acid -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H3O2R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "59.04400" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "59.01330" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC(=O)O[*]" xsd:string - -[Term] -id: CHEBI:47788 -name: 3-oxo steroid -namespace: chebi_ontology -alt_id: CHEBI:13607 -alt_id: CHEBI:1653 -alt_id: CHEBI:20182 -alt_id: CHEBI:71186 -def: "Any oxo steroid where an oxo substituent is located at position 3." [] -subset: 3_STAR -synonym: "3-oxo steroids" RELATED [ChEBI] -synonym: "3-Oxosteroid" RELATED [KEGG_COMPOUND] -synonym: "3-oxosteroids" RELATED [ChEBI] -synonym: "a 3-oxosteroid" RELATED [UniProt] -xref: KEGG:C01876 -xref: MetaCyc:3-Oxosteroids -xref: PMID:9811880 {source="SUBMITTER"} -is_a: CHEBI:35789 ! oxo steroid -is_a: CHEBI:3992 ! cyclic ketone -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C19H29OR" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "273.434" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "273.22184" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C12C(C3C(C(CC3)*)(C)CC1)CCC4C2(CCC(C4)=O)C" xsd:string - -[Term] -id: CHEBI:47891 -name: steroid acid -namespace: chebi_ontology -def: "Any steroid substituted by at least one carboxy group." [] -subset: 3_STAR -synonym: "steroid acids" RELATED [ChEBI] -is_a: CHEBI:35341 ! steroid -is_a: CHEBI:64709 ! organic acid -relationship: is_conjugate_acid_of CHEBI:50160 ! steroid acid anion - -[Term] -id: CHEBI:47909 -name: 3-oxo-Delta(4) steroid -namespace: chebi_ontology -alt_id: CHEBI:13604 -alt_id: CHEBI:1626 -alt_id: CHEBI:20157 -def: "A 3-oxo steroid conjugated to a C=C double bond at the alpha,beta position." [] -subset: 3_STAR -synonym: "3-oxo Delta(4)-steroid" RELATED [ChEBI] -synonym: "3-oxo Delta(4)-steroids" RELATED [ChEBI] -synonym: "3-oxo-Delta(4) steroids" RELATED [ChEBI] -synonym: "3-Oxo-delta4-steroid" RELATED [KEGG_COMPOUND] -synonym: "a 3-oxo-Delta(4)-steroid" RELATED [UniProt] -xref: KEGG:C00619 -xref: MetaCyc:3-Oxo-Delta-4-Steroids -is_a: CHEBI:47788 ! 3-oxo steroid -is_a: CHEBI:51689 ! enone -relationship: has_part CHEBI:136849 ! 3-oxo-Delta(4)-steroid group -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C19H27OR" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "271.418" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "271.20619" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C12C(C3C(C(CC3)*)(C)CC1)CCC=4C2(CCC(C4)=O)C" xsd:string - -[Term] -id: CHEBI:48154 -name: sulfur oxide -namespace: chebi_ontology -subset: 3_STAR -synonym: "oxides of sulfur" RELATED [ChEBI] -synonym: "Schwefeloxide" RELATED [ChEBI] -synonym: "sulfur oxides" RELATED [ChEBI] -is_a: CHEBI:24836 ! inorganic oxide -is_a: CHEBI:26835 ! sulfur molecular entity - -[Term] -id: CHEBI:48354 -name: polar solvent -namespace: chebi_ontology -def: "A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds." [] -subset: 3_STAR -synonym: "polar solvent" EXACT IUPAC_NAME [IUPAC] -synonym: "polar solvents" RELATED [ChEBI] -is_a: CHEBI:46787 ! solvent - -[Term] -id: CHEBI:48356 -name: protic solvent -namespace: chebi_ontology -def: "A polar solvent that is capable of acting as a hydron (proton) donor." [] -subset: 3_STAR -synonym: "protogenic solvent" EXACT IUPAC_NAME [IUPAC] -is_a: CHEBI:39141 ! Bronsted acid -is_a: CHEBI:48354 ! polar solvent - -[Term] -id: CHEBI:48359 -name: protophilic solvent -namespace: chebi_ontology -def: "Solvent that is capable of acting as a hydron (proton) acceptor." [] -subset: 3_STAR -synonym: "HBA solvent" RELATED [ChEBI] -synonym: "hydrogen bond acceptor solvent" RELATED [ChEBI] -synonym: "protophilic solvent" EXACT IUPAC_NAME [IUPAC] -is_a: CHEBI:39142 ! Bronsted base -is_a: CHEBI:48354 ! polar solvent - -[Term] -id: CHEBI:48360 -name: amphiprotic solvent -namespace: chebi_ontology -def: "Self-ionizing solvent possessing both characteristics of Bronsted acids and bases." [] -subset: 3_STAR -synonym: "amphiprotic solvent" EXACT IUPAC_NAME [IUPAC] -is_a: CHEBI:48356 ! protic solvent -is_a: CHEBI:48359 ! protophilic solvent - -[Term] -id: CHEBI:48539 -name: alpha-adrenergic drug -namespace: chebi_ontology -def: "Any drug that acts on an alpha-adrenergic receptor." [] -subset: 3_STAR -synonym: "alpha-adrenergic drugs" RELATED [ChEBI] -is_a: CHEBI:37962 ! adrenergic agent - -[Term] -id: CHEBI:48540 -name: beta-adrenergic drug -namespace: chebi_ontology -def: "Any of the drugs that act on beta-adrenergic receptors." [] -subset: 3_STAR -synonym: "beta-adrenergic drugs" RELATED [ChEBI] -is_a: CHEBI:37962 ! adrenergic agent - -[Term] -id: CHEBI:48560 -name: dopaminergic agent -namespace: chebi_ontology -def: "A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons." [] -subset: 3_STAR -synonym: "dopamine agent" RELATED [ChEBI] -synonym: "dopamine agents" RELATED [ChEBI] -synonym: "dopamine drug" RELATED [ChEBI] -synonym: "dopamine drugs" RELATED [ChEBI] -synonym: "dopaminergic agents" RELATED [ChEBI] -is_a: CHEBI:35942 ! neurotransmitter agent - -[Term] -id: CHEBI:48578 -name: radical scavenger -namespace: chebi_ontology -def: "A role played by a substance that can react readily with, and thereby eliminate, radicals." [] -subset: 3_STAR -synonym: "free radical scavengers" RELATED [ChEBI] -synonym: "free-radical scavenger" RELATED [ChEBI] -is_a: CHEBI:22586 ! antioxidant - -[Term] -id: CHEBI:48705 -name: agonist -namespace: chebi_ontology -def: "Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own." [] -subset: 3_STAR -synonym: "agonist" EXACT IUPAC_NAME [IUPAC] -synonym: "agonista" RELATED [ChEBI] -synonym: "agoniste" RELATED [ChEBI] -synonym: "agonists" RELATED [ChEBI] -is_a: CHEBI:52210 ! pharmacological role - -[Term] -id: CHEBI:49323 -name: contraceptive drug -namespace: chebi_ontology -def: "A chemical substance that prevents or reduces the probability of conception." [] -subset: 3_STAR -synonym: "contraceptive agent" RELATED [ChEBI] -synonym: "contraceptive drugs" RELATED [ChEBI] -is_a: CHEBI:50689 ! reproductive control drug - -[Term] -id: CHEBI:49637 -name: hydrogen atom -namespace: chebi_ontology -alt_id: CHEBI:24634 -alt_id: CHEBI:49636 -subset: 3_STAR -synonym: "1H" RELATED [IUPAC] -synonym: "H" RELATED [IUPAC] -synonym: "hidrogeno" RELATED [ChEBI] -synonym: "hydrogen" EXACT IUPAC_NAME [IUPAC] -synonym: "hydrogen" RELATED [ChEBI] -synonym: "hydrogene" RELATED [ChEBI] -synonym: "Wasserstoff" RELATED [ChEBI] -xref: WebElements:H -is_a: CHEBI:24835 ! inorganic molecular entity -is_a: CHEBI:25585 ! nonmetal atom -is_a: CHEBI:33559 ! s-block element atom -relationship: RO:0000087 CHEBI:33937 ! has role macronutrient -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "H" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "YZCKVEUIGOORGS-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "1.00794" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "1.00783" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]" xsd:string - [Term] id: CHEBI:50047 -name: organic amino compound namespace: chebi_ontology def: "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups." [ANON:ANON] -subset: 3_STAR -synonym: "organic amino compounds" RELATED [ChEBI] synonym: "organic amino compounds" RELATED [ChEBI:] -is_a: CHEBI:35352 ! organonitrogen compound -relationship: has_parent_hydride CHEBI:16134 ! ammonia -relationship: RO:0000087 CHEBI:39142 ! has role Bronsted base - -[Term] -id: CHEBI:50103 -name: excitatory amino acid agonist -namespace: chebi_ontology -def: "An agent that binds to and activates excitatory amino acid receptors." [] -subset: 3_STAR -synonym: "excitatory amino acid agonists" RELATED [ChEBI] -synonym: "excitatory amino acid receptor agonist" RELATED [ChEBI] -synonym: "excitatory amino acid receptor agonists" RELATED [ChEBI] -is_a: CHEBI:35942 ! neurotransmitter agent - -[Term] -id: CHEBI:50112 -name: sex hormone -namespace: chebi_ontology -def: "Any hormone that is responsible for controlling sexual characteristics and reproductive function." [] -subset: 3_STAR -synonym: "Geschlechtshormon" RELATED [ChEBI] -synonym: "Geschlechtshormone" RELATED [ChEBI] -synonym: "hormone sexuelle" RELATED [ChEBI] -synonym: "hormones sexuelles" RELATED [ChEBI] -synonym: "sex hormones" RELATED [ChEBI] -synonym: "Sexualhormon" RELATED [ChEBI] -synonym: "Sexualhormone" RELATED [ChEBI] -is_a: CHEBI:24621 ! hormone - -[Term] -id: CHEBI:50113 -name: androgen -namespace: chebi_ontology -def: "A sex hormone that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors." [] -subset: 3_STAR -synonym: "Androgen" EXACT [ChEBI] -synonym: "Androgene" RELATED [ChEBI] -synonym: "androgene" RELATED [ChEBI] -synonym: "androgenes" RELATED [ChEBI] -synonym: "androgeno" RELATED [ChEBI] -synonym: "androgenos" RELATED [ChEBI] -synonym: "androgens" RELATED [ChEBI] -is_a: CHEBI:50112 ! sex hormone - -[Term] -id: CHEBI:50114 -name: estrogen -namespace: chebi_ontology -def: "A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens." [] -subset: 3_STAR -synonym: "Estrogene" RELATED [ChEBI] -synonym: "estrogene" RELATED [ChEBI] -synonym: "estrogenes" RELATED [ChEBI] -synonym: "estrogenes Hormon" RELATED [ChEBI] -synonym: "estrogeno" RELATED [ChEBI] -synonym: "estrogenos" RELATED [ChEBI] -synonym: "estrogens" RELATED [ChEBI] -synonym: "Oestrogen" RELATED [ChEBI] -synonym: "oestrogen" RELATED [ChEBI] -synonym: "Oestrogene" RELATED [ChEBI] -synonym: "oestrogene" RELATED [ChEBI] -synonym: "oestrogenes" RELATED [ChEBI] -synonym: "oestrogens" RELATED [ChEBI] -xref: Wikipedia:Estrogen -is_a: CHEBI:50112 ! sex hormone - -[Term] -id: CHEBI:50160 -name: steroid acid anion -namespace: chebi_ontology -def: "Any anion formed by loss of a proton from a steroid acid." [] -subset: 3_STAR -synonym: "steroid acid anions" RELATED [ChEBI] -is_a: CHEBI:29067 ! carboxylic acid anion -relationship: is_conjugate_base_of CHEBI:47891 ! steroid acid - -[Term] -id: CHEBI:50267 -name: protective agent -namespace: chebi_ontology -def: "Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent." [] -subset: 3_STAR -synonym: "chemoprotectant" RELATED [ChEBI] -synonym: "chemoprotectants" RELATED [ChEBI] -synonym: "chemoprotective agent" RELATED [ChEBI] -synonym: "chemoprotective agents" RELATED [ChEBI] -synonym: "protective agents" RELATED [ChEBI] -is_a: CHEBI:23888 ! drug - -[Term] -id: CHEBI:50297 -name: canonical nucleotide residue -namespace: chebi_ontology -subset: 3_STAR -synonym: "canonical nucleotide residues" RELATED [ChEBI] -is_a: CHEBI:50319 ! nucleotide residue - -[Term] -id: CHEBI:50298 -name: canonical deoxyribonucleotide residue -namespace: chebi_ontology -subset: 3_STAR -synonym: "canonical deoxyribonucleotide residues" RELATED [ChEBI] -is_a: CHEBI:50297 ! canonical nucleotide residue - -[Term] -id: CHEBI:50299 -name: canonical ribonucleotide residue -namespace: chebi_ontology -subset: 3_STAR -synonym: "canonical ribonucleotide residues" RELATED [ChEBI] -is_a: CHEBI:50297 ! canonical nucleotide residue - -[Term] -id: CHEBI:50312 -name: onium compound -namespace: chebi_ontology -subset: 1_STAR -is_a: CHEBI:37577 ! heteroatomic molecular entity - -[Term] -id: CHEBI:50313 -name: onium cation -namespace: chebi_ontology -def: "Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families." [] -subset: 3_STAR -synonym: "onium cations" EXACT IUPAC_NAME [IUPAC] -synonym: "onium cations" RELATED [ChEBI] -synonym: "onium ion" RELATED [ChEBI] -synonym: "onium ions" RELATED [ChEBI] -is_a: CHEBI:50312 ! onium compound - -[Term] -id: CHEBI:50319 -name: nucleotide residue -namespace: chebi_ontology -subset: 3_STAR -synonym: "nucleotide residues" RELATED [ChEBI] -is_a: CHEBI:33247 ! organic group - -[Term] -id: CHEBI:50320 -name: nucleoside residue -namespace: chebi_ontology -subset: 3_STAR -synonym: "nucleoside residues" RELATED [ChEBI] -is_a: CHEBI:33247 ! organic group - -[Term] -id: CHEBI:50325 -name: proteinogenic amino-acid side-chain group -namespace: chebi_ontology -def: "A univalent organyl group obtained by cleaving the bond from C-2 to the side chain of a proteinogenic amino-acid." [] -subset: 3_STAR -synonym: "canonical amino-acid side-chain" RELATED [ChEBI] -synonym: "canonical amino-acid side-chains" RELATED [ChEBI] -synonym: "proteinogenic amino-acid side-chain" RELATED [ChEBI] -synonym: "proteinogenic amino-acid side-chain groups" RELATED [ChEBI] -synonym: "proteinogenic amino-acid side-chains" RELATED [ChEBI] -is_a: CHEBI:33249 ! organyl group - -[Term] -id: CHEBI:50329 -name: 2-carboxyethyl group -namespace: chebi_ontology -subset: 3_STAR -synonym: "2-carboxyethyl" EXACT IUPAC_NAME [IUPAC] -synonym: "glutamic acid side-chain" RELATED [ChEBI] -is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C3H5O2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "73.07060" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "73.02895" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C(CC(=O)O)*" xsd:string - -[Term] -id: CHEBI:50402 -name: androstanoid -namespace: chebi_ontology -def: "Any steroid based on an androstane skeleton and its derivatives." [] -subset: 3_STAR -synonym: "androstanoids" RELATED [ChEBI] -is_a: CHEBI:35341 ! steroid -relationship: has_parent_hydride CHEBI:35509 ! androstane - -[Term] -id: CHEBI:50514 -name: vasoconstrictor agent -namespace: chebi_ontology -def: "Drug used to cause constriction of the blood vessels." [] -subset: 3_STAR -is_a: CHEBI:35554 ! cardiovascular drug - -[Term] -id: CHEBI:50646 -name: bone density conservation agent -namespace: chebi_ontology -alt_id: CHEBI:72497 -def: "An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis." [] -subset: 3_STAR -synonym: "anti-osteopenia agent" RELATED [ChEBI] -synonym: "anti-osteopenia agents" RELATED [ChEBI] -synonym: "anti-osteopenia drug" RELATED [ChEBI] -synonym: "anti-osteopenia drugs" RELATED [ChEBI] -synonym: "anti-osteoporosis agent" RELATED [ChEBI] -synonym: "anti-osteoporosis agents" RELATED [ChEBI] -synonym: "anti-osteoporosis drug" RELATED [ChEBI] -synonym: "anti-osteoporosis drugs" RELATED [ChEBI] -synonym: "anti-osteoporotic" RELATED [ChEBI] -synonym: "anti-osteoporotic agent" RELATED [ChEBI] -synonym: "anti-osteoporotic agents" RELATED [ChEBI] -synonym: "anti-osteoporotic drug" RELATED [ChEBI] -synonym: "anti-osteoporotic drugs" RELATED [ChEBI] -synonym: "anti-osteoporotics" RELATED [ChEBI] -synonym: "antiosteoporotic" RELATED [ChEBI] -synonym: "antiosteoporotics" RELATED [ChEBI] -synonym: "bone density conservation agents" RELATED [ChEBI] -synonym: "bone density conservation drug" RELATED [ChEBI] -synonym: "bone density conservation drugs" RELATED [ChEBI] -xref: Wikipedia:Osteoporosis -is_a: CHEBI:23888 ! drug - -[Term] -id: CHEBI:50689 -name: reproductive control drug -namespace: chebi_ontology -def: "A substance used either in the prevention or facilitation of pregnancy." [] -subset: 3_STAR -synonym: "reproductive control agent" RELATED [ChEBI] -synonym: "reproductive control drugs" RELATED [ChEBI] -is_a: CHEBI:23888 ! drug - -[Term] -id: CHEBI:50733 -name: nutraceutical -namespace: chebi_ontology -def: "A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance." [] -subset: 3_STAR -synonym: "Dietary Supplement" RELATED [ChEBI] -synonym: "Food Supplementation" RELATED [ChEBI] -synonym: "Nutritional supplement" RELATED [ChEBI] -is_a: CHEBI:23888 ! drug - -[Term] -id: CHEBI:50745 -name: progestogen -namespace: chebi_ontology -def: "A compound that interacts with progesterone receptors in target tissues to bring about effects similar to those of progesterone." [] -subset: 3_STAR -synonym: "gestagen" RELATED [ChEBI] -synonym: "gestagens" RELATED [ChEBI] -synonym: "progestagen" RELATED [ChEBI] -synonym: "progestagens" RELATED [ChEBI] -synonym: "progestogens" RELATED [ChEBI] -is_a: CHEBI:50112 ! sex hormone - -[Term] -id: CHEBI:50779 -name: appetite enhancer -namespace: chebi_ontology -def: "A drug which increases appetite." [] -subset: 3_STAR -synonym: "appetite enhancing drug" RELATED [ChEBI] -synonym: "appetite stimulant" RELATED [ChEBI] -synonym: "orexigenic" RELATED [ChEBI] -xref: Wikipedia:Appetite_stimulants -is_a: CHEBI:50780 ! appetite regulator - -[Term] -id: CHEBI:50780 -name: appetite regulator -namespace: chebi_ontology -def: "An agent which regulates the physiologic mechanisms that control the appetite and food intake." [] -subset: 3_STAR -synonym: "appetite regulators" RELATED [ChEBI] -is_a: CHEBI:23888 ! drug - -[Term] -id: CHEBI:50846 -name: immunomodulator -namespace: chebi_ontology -def: "Biologically active substance whose activity affects or plays a role in the functioning of the immune system." [] -subset: 3_STAR -synonym: "Biomodulator" RELATED [ChEBI] -synonym: "Immune factor" RELATED [ChEBI] -synonym: "Immunologic factor" RELATED [ChEBI] -synonym: "Immunological factor" RELATED [ChEBI] -synonym: "immunomodulators" RELATED [ChEBI] -xref: Wikipedia:Immunotherapy -is_a: CHEBI:23888 ! drug -is_a: CHEBI:24432 ! biological role - -[Term] -id: CHEBI:50847 -name: immunological adjuvant -namespace: chebi_ontology -def: "A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity." [] -subset: 3_STAR -synonym: "Immunoactivator" RELATED [ChEBI] -synonym: "Immunoadjuvant" RELATED [ChEBI] -synonym: "Immunologic adjuvant" RELATED [ChEBI] -synonym: "Immunopotentiator" RELATED [ChEBI] -synonym: "Immunostimulant" RELATED [ChEBI] -xref: Wikipedia:Immunologic_adjuvant -is_a: CHEBI:50846 ! immunomodulator -is_a: CHEBI:60809 ! adjuvant - -[Term] -id: CHEBI:50855 -name: antiatherogenic agent -namespace: chebi_ontology -def: "A cardiovascular drug that prevents atherogenesis, the accumulation of lipid-containing plaques on the innermost layers of the arteries. Compare with antiatherosclerotic agent." [] -subset: 3_STAR -synonym: "anti-atherogenic agent" RELATED [ChEBI] -synonym: "anti-atherogenic agents" RELATED [ChEBI] -synonym: "anti-atherogenic drug" RELATED [ChEBI] -synonym: "anti-atherogenic drugs" RELATED [ChEBI] -synonym: "antiatherogenic agent" EXACT [ChEBI] -synonym: "antiatherogenic agents" RELATED [ChEBI] -synonym: "antiatherogenic drug" RELATED [ChEBI] -synonym: "antiatherogenic drugs" RELATED [ChEBI] -xref: PMID:14592471 {source="Europe PMC"} -xref: PMID:16366593 {source="Europe PMC"} -xref: PMID:17990280 {source="Europe PMC"} -xref: PMID:20222342 {source="Europe PMC"} -xref: PMID:21074432 {source="Europe PMC"} -xref: PMID:21172387 {source="Europe PMC"} -xref: PMID:21649483 {source="Europe PMC"} -xref: PMID:3288054 {source="Europe PMC"} -xref: PMID:9796331 {source="Europe PMC"} -is_a: CHEBI:35554 ! cardiovascular drug - -[Term] -id: CHEBI:50858 -name: corticosteroid -namespace: chebi_ontology -def: "A natural or synthetic analogue of the hormones secreted by the adrenal gland." [] -subset: 3_STAR -synonym: "corticoides" RELATED [ChEBI] -synonym: "corticosteroides" RELATED [ChEBI] -synonym: "corticosteroids" RELATED [ChEBI] -is_a: CHEBI:35341 ! steroid [Term] id: CHEBI:50860 -name: organic molecular entity namespace: chebi_ontology -alt_id: CHEBI:25700 -alt_id: CHEBI:33244 def: "Any molecular entity that contains carbon." [ANON:ANON] -subset: 3_STAR -synonym: "organic compounds" RELATED [ChEBI] synonym: "organic compounds" RELATED [ChEBI:] -synonym: "organic entity" RELATED [ChEBI] synonym: "organic entity" RELATED [ChEBI:] synonym: "organic molecular entities" RELATED [ChEBI:] -synonym: "organic molecular entities" RELATED [ChEBI] -is_a: CHEBI:33582 ! carbon group molecular entity -relationship: has_part CHEBI:27594 ! carbon atom [Term] id: CHEBI:50906 -name: role -namespace: chebi_ontology -def: "A role is particular behaviour which a material entity may exhibit." [] -subset: 3_STAR is_a: BFO:0000023 ! role -[Term] -id: CHEBI:50910 -name: neurotoxin -namespace: chebi_ontology -alt_id: CHEBI:50911 -def: "A poison that interferes with the functions of the nervous system." [] -subset: 3_STAR -synonym: "agente neurotoxico" RELATED [ChEBI] -synonym: "nerve poison" RELATED [ChEBI] -synonym: "nerve poisons" RELATED [ChEBI] -synonym: "neurotoxic agent" RELATED [ChEBI] -synonym: "neurotoxic agents" RELATED [ChEBI] -synonym: "neurotoxicant" RELATED [ChEBI] -synonym: "neurotoxins" RELATED [ChEBI] -xref: Wikipedia:Neurotoxin -is_a: CHEBI:52209 ! aetiopathogenetic role -is_a: CHEBI:64909 ! poison - -[Term] -id: CHEBI:50967 -name: non-covalently-bound molecular entity -namespace: chebi_ontology -def: "Systems consisting of two or more molecular entities held together by non-covalent interactions." [] -subset: 3_STAR -synonym: "non-covalently-bound molecular entities" RELATED [ChEBI] -is_a: CHEBI:36357 ! polyatomic entity - [Term] id: CHEBI:50994 -name: primary amino compound namespace: chebi_ontology def: "A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group." [ANON:ANON] -subset: 3_STAR -synonym: "primary amino compounds" RELATED [ChEBI] synonym: "primary amino compounds" RELATED [ChEBI:] -is_a: CHEBI:50047 ! organic amino compound -relationship: is_conjugate_base_of CHEBI:65296 ! primary ammonium ion - -[Term] -id: CHEBI:51060 -name: hormone agonist -namespace: chebi_ontology -def: "A chemical substance which binds to specific hormone receptors activating the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites." [] -subset: 3_STAR -is_a: CHEBI:48705 ! agonist -is_a: CHEBI:51061 ! hormone receptor modulator - -[Term] -id: CHEBI:51061 -name: hormone receptor modulator -namespace: chebi_ontology -def: "A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites." [] -subset: 3_STAR -synonym: "hormone receptor modulators" RELATED [ChEBI] -is_a: CHEBI:90710 ! receptor modulator - -[Term] -id: CHEBI:51086 -name: chemical role -namespace: chebi_ontology -def: "A role played by the molecular entity or part thereof within a chemical context." [] -subset: 3_STAR -is_a: BFO:0000023 ! role -is_a: CHEBI:50906 ! role [Term] id: CHEBI:51143 -name: nitrogen molecular entity namespace: chebi_ontology -alt_id: CHEBI:25556 -alt_id: CHEBI:7594 -subset: 3_STAR synonym: "nitrogen compounds" RELATED [ChEBI:] -synonym: "nitrogen compounds" RELATED [ChEBI] -synonym: "nitrogen molecular entities" RELATED [ChEBI] synonym: "nitrogen molecular entities" RELATED [ChEBI:] synonym: "Nitrogenous compounds" RELATED [KEGG COMPOUND:] -synonym: "Nitrogenous compounds" RELATED [KEGG_COMPOUND] -xref: KEGG:C06061 -is_a: CHEBI:33302 ! pnictogen molecular entity -relationship: has_part CHEBI:25555 ! nitrogen atom - -[Term] -id: CHEBI:51151 -name: dipolar compound -namespace: chebi_ontology -def: "An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case." [] -subset: 3_STAR -synonym: "dipolar compounds" RELATED [ChEBI] -is_a: CHEBI:72695 ! organic molecule - -[Term] -id: CHEBI:51422 -name: organodiyl group -namespace: chebi_ontology -def: "Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s)." [] -subset: 3_STAR -synonym: "organodiyl groups" RELATED [ChEBI] -is_a: CHEBI:51446 ! organic divalent group - -[Term] -id: CHEBI:51446 -name: organic divalent group -namespace: chebi_ontology -subset: 1_STAR -is_a: CHEBI:33247 ! organic group - -[Term] -id: CHEBI:51447 -name: organic univalent group -namespace: chebi_ontology -subset: 1_STAR -is_a: CHEBI:33247 ! organic group - -[Term] -id: CHEBI:51689 -name: enone -namespace: chebi_ontology -def: "An alpha,beta-unsaturated ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) in which the C=O function is conjugated to a C=C double bond at the alpha,beta position." [] -subset: 3_STAR -synonym: "enones" RELATED [ChEBI] -xref: Wikipedia:Enone -is_a: CHEBI:51721 ! alpha,beta-unsaturated ketone -is_a: CHEBI:78840 ! olefinic compound -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C3OR4" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "52.03150" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "51.99491" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]\\C([*])=C(\\[*])C([*])=O" xsd:string - -[Term] -id: CHEBI:51721 -name: alpha,beta-unsaturated ketone -namespace: chebi_ontology -def: "A ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) or R(1)C#C-C(=O)R(2) (R(2) =/= H) in which the ketonic C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position." [] -subset: 3_STAR -synonym: "alpha,beta-unsaturated ketones" RELATED [ChEBI] -is_a: CHEBI:17087 ! ketone - -[Term] -id: CHEBI:51958 -name: organic polycyclic compound -namespace: chebi_ontology -subset: 3_STAR -synonym: "organic polycyclic compounds" RELATED [ChEBI] -is_a: CHEBI:33635 ! polycyclic compound -is_a: CHEBI:33832 ! organic cyclic compound - -[Term] -id: CHEBI:52206 -name: biochemical role -namespace: chebi_ontology -def: "A biological role played by the molecular entity or part thereof within a biochemical context." [] -subset: 3_STAR -is_a: CHEBI:24432 ! biological role - -[Term] -id: CHEBI:52209 -name: aetiopathogenetic role -namespace: chebi_ontology -def: "A role played by the molecular entity or part thereof which causes the development of a pathological process." [] -subset: 3_STAR -synonym: "etiopathogenetic agent" RELATED [ChEBI] -synonym: "etiopathogenetic role" RELATED [ChEBI] -is_a: CHEBI:24432 ! biological role - -[Term] -id: CHEBI:52210 -name: pharmacological role -namespace: chebi_ontology -def: "A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties." [] -subset: 3_STAR -is_a: CHEBI:24432 ! biological role - -[Term] -id: CHEBI:52211 -name: physiological role -namespace: chebi_ontology -subset: 1_STAR -is_a: CHEBI:24432 ! biological role - -[Term] -id: CHEBI:52217 -name: pharmaceutical -namespace: chebi_ontology -alt_id: CHEBI:33293 -alt_id: CHEBI:33294 -def: "Any substance introduced into a living organism with therapeutic or diagnostic purpose." [] -subset: 3_STAR -synonym: "farmaco" RELATED [ChEBI] -synonym: "medicament" RELATED [ChEBI] -synonym: "pharmaceuticals" RELATED [ChEBI] -is_a: CHEBI:33232 ! application - -[Term] -id: CHEBI:52254 -name: apatite -namespace: chebi_ontology -def: "A phosphate mineral with the general formula Ca5(PO4)3X where X = OH, F or Cl." [] -subset: 3_STAR -synonym: "hydroxyapatite" RELATED [ChEBI] -xref: HMDB:HMDB0033610 -is_a: CHEBI:46723 ! phosphate mineral - -[Term] -id: CHEBI:52255 -name: hydroxylapatite -namespace: chebi_ontology -def: "A phosphate mineral with the formula Ca5(PO4)3(OH)." [] -subset: 3_STAR -is_a: CHEBI:52254 ! apatite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "Ca5HO13P3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "502.312" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "501.67595" xsd:string - -[Term] -id: CHEBI:52395 -name: oxyketone -namespace: chebi_ontology -def: "A compound with the general formula R2C=O (R=/=H) where one or more of the R groups contains an oxy (-O-) group." [] -subset: 3_STAR -synonym: "oxyketones" RELATED [ChEBI] -is_a: CHEBI:17087 ! ketone - -[Term] -id: CHEBI:52396 -name: alpha-oxyketone -namespace: chebi_ontology -def: "An oxyketone with the general formula R2C(=O) (R=/=H) where one or more of the R groups contains an oxy (-O-) group and the oxy and carbonyl groups are bonded to the same carbon atom." [] -subset: 3_STAR -synonym: "alpha-oxyketones" RELATED [ChEBI] -is_a: CHEBI:52395 ! oxyketone - -[Term] -id: CHEBI:52625 -name: inorganic hydroxy compound -namespace: chebi_ontology -subset: 3_STAR -synonym: "inorganic hydroxides" RELATED [ChEBI] -is_a: CHEBI:24651 ! hydroxides -is_a: CHEBI:24835 ! inorganic molecular entity - -[Term] -id: CHEBI:52845 -name: cyclic organic group -namespace: chebi_ontology -def: "An organic group that consists of a closed ring. It may be a substituent or a skeleton." [] -subset: 3_STAR -synonym: "cyclic organic groups" RELATED [ChEBI] -is_a: CHEBI:33247 ! organic group - -[Term] -id: CHEBI:53000 -name: epitope -namespace: chebi_ontology -def: "The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds." [] -subset: 3_STAR -synonym: "antigenic determinant" RELATED [ChEBI] -synonym: "epitope function" RELATED [ChEBI] -synonym: "epitope role" RELATED [ChEBI] -is_a: CHEBI:24432 ! biological role - -[Term] -id: CHEBI:53309 -name: polyanionic macromolecule -namespace: chebi_ontology -def: "A polymer carrying multiple negative charges." [] -subset: 3_STAR -synonym: "polyanion" RELATED [ChEBI] -synonym: "polyanions" RELATED [SUBMITTER] -is_a: CHEBI:53368 ! ionic macromolecule - -[Term] -id: CHEBI:53368 -name: ionic macromolecule -namespace: chebi_ontology -def: "A macromolecule containing ionic groups." [] -subset: 3_STAR -synonym: "ionic polymer" RELATED [ChEBI] -synonym: "polyionic macromolecule" RELATED [ChEBI] -is_a: CHEBI:33839 ! macromolecule - -[Term] -id: CHEBI:5391 -name: glucagon -namespace: chebi_ontology -def: "A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence." [] -subset: 3_STAR -synonym: "Glucagon" EXACT [KEGG_COMPOUND] -synonym: "glucagon" RELATED INN [ChemIDplus] -synonym: "Glucagone" RELATED [ChemIDplus] -synonym: "glucagonum" RELATED INN [ChemIDplus] -synonym: "His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr" RELATED [ChEBI] -synonym: "His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr" RELATED [ChemIDplus] -synonym: "HSQGTFTSDYSKYLDSRRAQDFVQWLMNT" RELATED [ChEBI] -synonym: "L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine" EXACT IUPAC_NAME [IUPAC] -xref: CAS:16941-32-5 {source="ChemIDplus"} -xref: CAS:9007-92-5 {source="KEGG COMPOUND"} -xref: CAS:9007-92-5 {source="ChemIDplus"} -xref: Drug_Central:2994 {source="DrugCentral"} -xref: DrugBank:DB00040 -xref: KEGG:C01501 -xref: KEGG:D00116 -xref: PMID:21940356 {source="Europe PMC"} -xref: PMID:22014161 {source="Europe PMC"} -xref: PMID:22154917 {source="Europe PMC"} -xref: PMID:22166985 {source="Europe PMC"} -xref: PMID:22167521 {source="Europe PMC"} -xref: PMID:22214853 {source="Europe PMC"} -xref: PMID:22227186 {source="Europe PMC"} -xref: PMID:22286080 {source="Europe PMC"} -xref: PMID:22294753 {source="Europe PMC"} -xref: PMID:22318544 {source="Europe PMC"} -xref: PMID:22334714 {source="Europe PMC"} -xref: PMID:22399501 {source="Europe PMC"} -xref: PMID:22438981 {source="Europe PMC"} -xref: PMID:22454291 {source="Europe PMC"} -xref: Reaxys:13191924 {source="Reaxys"} -xref: Wikipedia:Glucagon -is_a: CHEBI:25905 ! peptide hormone -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C153H225N43O49S" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132(225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100(57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112(156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,30-32,41-63,66-70,154-155H2,1-11H3,(H2,156,206)(H2,157,207)(H2,158,208)(H2,159,209)(H,164,169)(H,168,219)(H,170,220)(H,171,217)(H,172,221)(H,173,238)(H,174,239)(H,175,237)(H,176,226)(H,177,241)(H,178,228)(H,179,230)(H,180,222)(H,181,232)(H,182,231)(H,183,224)(H,184,225)(H,185,223)(H,186,227)(H,187,240)(H,188,242)(H,189,218)(H,190,229)(H,191,233)(H,192,243)(H,193,210)(H,194,234)(H,195,235)(H,196,236)(H,211,212)(H,213,214)(H,215,216)(H,244,245)(H4,160,161,165)(H4,162,163,166)/t75-,76+,77+,78+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-/m0/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "MASNOZXLGMXCHN-ZLPAWPGGSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "3482.74700" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "3480.61570" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O" xsd:string [Term] id: CHEBI:5686 -name: heterocyclic compound namespace: chebi_ontology def: "A cyclic compound having as ring members atoms of at least two different elements." [ANON:ANON] -subset: 3_STAR -synonym: "compuesto heterociclico" RELATED [IUPAC] synonym: "compuesto heterociclico" RELATED [IUPAC:] synonym: "compuestos heterociclicos" RELATED [IUPAC:] -synonym: "compuestos heterociclicos" RELATED [IUPAC] synonym: "heterocycle" RELATED [ChEBI:] -synonym: "heterocycle" RELATED [ChEBI] synonym: "Heterocyclic compound" EXACT [KEGG COMPOUND:] -synonym: "Heterocyclic compound" EXACT [KEGG_COMPOUND] synonym: "heterocyclic compounds" RELATED [ChEBI:] -synonym: "heterocyclic compounds" RELATED [ChEBI] -is_a: CHEBI:33595 ! cyclic compound - -[Term] -id: CHEBI:57305 -name: glycine zwitterion -namespace: chebi_ontology -def: "An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of glycine." [] -subset: 3_STAR -synonym: "2-azaniumylacetate" EXACT IUPAC_NAME [IUPAC] -synonym: "glycine" RELATED [UniProt] -xref: Gmelin:1807 {source="Gmelin"} -xref: MetaCyc:GLY -is_a: CHEBI:35238 ! amino acid zwitterion -relationship: is_tautomer_of CHEBI:15428 ! glycine -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H5NO2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "DHMQDGOQFOQNFH-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "75.06660" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "75.03203" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]CC([O-])=O" xsd:string - -[Term] -id: CHEBI:57652 -name: chondroitin D-glucuronate anion -namespace: chebi_ontology -def: "Anionic form of chondroitin D-glucuronate arising from deprotonation of the carboxylic acid groups of the repeating units; major species at pH 7.3." [] -subset: 3_STAR -synonym: "chondroitin D-glucuronate" RELATED [UniProt] -synonym: "chondroitin D-glucuronate polyanion" RELATED [ChEBI] -is_a: CHEBI:61469 ! polyanionic polymer -relationship: is_conjugate_base_of CHEBI:16137 ! chondroitin D-glucuronate -property_value: http://purl.obolibrary.org/obo/chebi/formula "H2O(C14H20NO11)n" xsd:string - -[Term] -id: CHEBI:57887 -name: tryptaminium -namespace: chebi_ontology -def: "An ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3." [] -subset: 3_STAR -synonym: "2-(1H-indol-3-yl)ethanaminium" EXACT IUPAC_NAME [IUPAC] -synonym: "tryptamine" RELATED [UniProt] -synonym: "tryptaminium cation" RELATED [ChEBI] -synonym: "tryptaminium(1+)" RELATED [ChEBI] -xref: Gmelin:533978 {source="Gmelin"} -is_a: CHEBI:65296 ! primary ammonium ion -relationship: is_conjugate_acid_of CHEBI:16765 ! tryptamine -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H13N2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2/p+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "APJYDQYYACXCRM-UHFFFAOYSA-O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "161.22310" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "161.10732" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]CCc1c[nH]c2ccccc12" xsd:string - -[Term] -id: CHEBI:57977 -name: bilirubin(2-) -namespace: chebi_ontology -def: "A dicarboxylic acid dianion obtained by deprotonation of the two carboxy groups of bilirubin; major species at pH 7.3." [] -subset: 3_STAR -synonym: "2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoate" RELATED [ChEBI] -synonym: "bilirubin dianion" RELATED [ChEBI] -synonym: "bilirubin IXalpha" RELATED [UniProt] -xref: Beilstein:4083310 {source="Beilstein"} -is_a: CHEBI:28965 ! dicarboxylic acid dianion -is_a: CHEBI:59252 ! linear tetrapyrrole anion -relationship: is_conjugate_base_of CHEBI:16990 ! bilirubin IXalpha -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C33H34N4O6" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/p-2/b26-13-,27-14-" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BPYKTIZUTYGOLE-IFADSCNNSA-L" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "582.64630" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "582.24893" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC1=C(C=C)\\C(NC1=O)=C\\c1[nH]c(Cc2[nH]c(\\C=C3NC(=O)C(C=C)=C/3C)c(C)c2CCC([O-])=O)c(CCC([O-])=O)c1C" xsd:string - -[Term] -id: CHEBI:58432 -name: histaminium -namespace: chebi_ontology -def: "An ammonium ion that is the conjugate acid of histamine protonated on the side-chain nitrogen." [] -subset: 3_STAR -synonym: "2-(1H-imidazol-4-yl)ethanaminium" EXACT IUPAC_NAME [IUPAC] -synonym: "histamine" RELATED [UniProt] -synonym: "histaminium cation" RELATED [ChEBI] -is_a: CHEBI:35274 ! ammonium ion derivative -relationship: is_conjugate_acid_of CHEBI:18295 ! histamine -relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H10N3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)/p+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NTYJJOPFIAHURM-UHFFFAOYSA-O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "112.15300" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "112.08692" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]CCc1c[nH]cn1" xsd:string - -[Term] -id: CHEBI:58951 -name: short-chain fatty acid anion -namespace: chebi_ontology -def: "Any fatty acid anion obtained by removal of a proton from the carboxy group of a short-chain fatty acid (chain length of less than C6)." [] -subset: 3_STAR -synonym: "a short-chain fatty acid" RELATED [UniProt] -synonym: "short-chain fatty acid anions" RELATED [ChEBI] -is_a: CHEBI:28868 ! fatty acid anion -relationship: is_conjugate_base_of CHEBI:26666 ! short-chain fatty acid -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "44.010" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([*])=O" xsd:string - -[Term] -id: CHEBI:58953 -name: saturated fatty acid anion -namespace: chebi_ontology -def: "Any fatty acid anion in which there is no C-C unsaturation." [] -subset: 3_STAR -synonym: "saturated fatty acid anions" RELATED [ChEBI] -is_a: CHEBI:28868 ! fatty acid anion - -[Term] -id: CHEBI:58954 -name: straight-chain saturated fatty acid anion -namespace: chebi_ontology -def: "Any saturated fatty acid anion lacking a carbon side-chain." [] -subset: 3_STAR -synonym: "straight-chain saturated fatty acid anions" RELATED [ChEBI] -is_a: CHEBI:58953 ! saturated fatty acid anion -relationship: is_conjugate_base_of CHEBI:39418 ! straight-chain saturated fatty acid - -[Term] -id: CHEBI:58958 -name: organosulfate oxoanion -namespace: chebi_ontology -def: "An organic anion of general formula RS(=O)2O(-) where R is an organyl group." [] -subset: 3_STAR -synonym: "organosulfate oxoanions" RELATED [ChEBI] -is_a: CHEBI:25696 ! organic anion -is_a: CHEBI:33482 ! sulfur oxoanion -relationship: has_functional_parent CHEBI:16189 ! sulfate -relationship: is_conjugate_base_of CHEBI:25704 ! organic sulfate -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "O4SR" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "96.06300" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.95173" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]S(=O)(=O)O[*]" xsd:string - -[Term] -id: CHEBI:59202 -name: straight-chain fatty acid -namespace: chebi_ontology -def: "Any fatty acid whose skeletal carbon atoms form an unbranched open chain." [] -subset: 3_STAR -synonym: "straight-chain fatty acids" RELATED [ChEBI] -is_a: CHEBI:35366 ! fatty acid -relationship: is_conjugate_acid_of CHEBI:59203 ! straight-chain fatty acid anion - -[Term] -id: CHEBI:59203 -name: straight-chain fatty acid anion -namespace: chebi_ontology -def: "A fatty acid anion formed by deprotonation of the carboxylic acid functional group of a straight-chain fatty acid." [] -subset: 3_STAR -synonym: "straight-chain FA anion" RELATED [ChEBI] -synonym: "straight-chain FA anions" RELATED [ChEBI] -synonym: "straight-chain fatty acid anions" RELATED [ChEBI] -is_a: CHEBI:28868 ! fatty acid anion -relationship: is_conjugate_base_of CHEBI:59202 ! straight-chain fatty acid - -[Term] -id: CHEBI:59252 -name: linear tetrapyrrole anion -namespace: chebi_ontology -def: "An organic anion arising from deprotonation of a acyclic tetrapyrrole compound." [] -subset: 3_STAR -synonym: "acyclic tetrapyrrole anion" RELATED [ChEBI] -synonym: "acyclic tetrapyrrole anions" RELATED [ChEBI] -synonym: "linear tetrapyrrole anions" RELATED [ChEBI] -is_a: CHEBI:25696 ! organic anion - -[Term] -id: CHEBI:59698 -name: phosphoric acids -namespace: chebi_ontology -def: "Compounds containing one or more phosphoric acid units." [] -subset: 3_STAR -is_a: CHEBI:33457 ! phosphorus oxoacid - -[Term] -id: CHEBI:59740 -name: nucleophilic reagent -namespace: chebi_ontology -def: "A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons." [] -subset: 3_STAR -synonym: "nucleophile" RELATED [ChEBI] -synonym: "nucleophiles" RELATED [ChEBI] -synonym: "nucleophilic reagents" RELATED [ChEBI] -is_a: CHEBI:33893 ! reagent -is_a: CHEBI:39144 ! Lewis base - -[Term] -id: CHEBI:59814 -name: L-alpha-amino acid anion -namespace: chebi_ontology -def: "Conjugate base of an L-alpha-amino acid arising from deprotonation of the C-1 carboxy group." [] -subset: 3_STAR -synonym: "L-alpha-amino carboxylate" RELATED [ChEBI] -is_a: CHEBI:33558 ! alpha-amino-acid anion -relationship: is_conjugate_base_of CHEBI:15705 ! L-alpha-amino acid -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H3NO2R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "73.051" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "73.01638" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[C@H](C(=O)[O-])(N)*" xsd:string - -[Term] -id: CHEBI:59826 -name: progestin -namespace: chebi_ontology -def: "A synthetic progestogen." [] -subset: 3_STAR -synonym: "progestins" RELATED [ChEBI] -xref: Wikipedia:Progestin -is_a: CHEBI:50745 ! progestogen - -[Term] -id: CHEBI:59869 -name: L-alpha-amino acid zwitterion -namespace: chebi_ontology -def: "Zwitterionic form of an L-alpha-amino acid having an anionic carboxy group and a protonated amino group." [] -subset: 3_STAR -synonym: "an L-alpha-amino acid" RELATED [UniProt] -synonym: "L-alpha-amino acid zwitterions" RELATED [ChEBI] -is_a: CHEBI:78608 ! alpha-amino acid zwitterion -relationship: is_tautomer_of CHEBI:15705 ! L-alpha-amino acid -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "74.059" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+][C@@H]([*])C([O-])=O" xsd:string - -[Term] -id: CHEBI:59888 -name: gamma-aminobutyric acid zwitterion -namespace: chebi_ontology -def: "Zwitterionic form of gamma-aminobutyric acid having an anionic carboxy group and a protonated amino group." [] -subset: 3_STAR -synonym: "4-aminobutanoate" RELATED [UniProt] -synonym: "4-ammoniobutanoate" RELATED [ChEBI] -synonym: "4-azaniumylbutanoate" EXACT IUPAC_NAME [IUPAC] -xref: Gmelin:1041559 {source="Gmelin"} -is_a: CHEBI:35238 ! amino acid zwitterion -relationship: is_tautomer_of CHEBI:16865 ! gamma-aminobutyric acid -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H9NO2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BTCSSZJGUNDROE-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "103.11980" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "103.06333" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]CCCC([O-])=O" xsd:string - -[Term] -id: CHEBI:59905 -name: dopaminium(1+) -namespace: chebi_ontology -def: "An ammonium ion that is the conjugate acid of dopamine; major species at pH 7.3." [] -subset: 3_STAR -synonym: "2-(3,4-dihydroxyphenyl)ethan-1-aminium" RELATED [ChEBI] -synonym: "2-(3,4-dihydroxyphenyl)ethanaminium" EXACT IUPAC_NAME [IUPAC] -synonym: "dopamine" RELATED [UniProt] -synonym: "dopaminium cation" RELATED [ChEBI] -xref: Gmelin:328863 {source="Gmelin"} -is_a: CHEBI:35274 ! ammonium ion derivative -relationship: is_conjugate_acid_of CHEBI:18243 ! dopamine -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H12NO2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2/p+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "VYFYYTLLBUKUHU-UHFFFAOYSA-O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "154.18640" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "154.08626" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]CCc1ccc(O)c(O)c1" xsd:string - -[Term] -id: CHEBI:59999 -name: chemical substance -namespace: chebi_ontology -def: "A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types." [] -subset: 3_STAR -synonym: "Chemische Substanz" RELATED [ChEBI] -is_a: CHEBI:24431 ! chemical entity - -[Term] -id: CHEBI:60004 -name: mixture -namespace: chebi_ontology -def: "A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind." [] -subset: 3_STAR -synonym: "Mischung" RELATED [ChEBI] -is_a: CHEBI:59999 ! chemical substance - -[Term] -id: CHEBI:60027 -name: polymer -namespace: chebi_ontology -def: "A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc.." [] -subset: 3_STAR -synonym: "Kunststoff" RELATED [ChEBI] -synonym: "Polymer" EXACT [ChEBI] -xref: Wikipedia:Polymer -is_a: CHEBI:60004 ! mixture -relationship: has_part CHEBI:33839 ! macromolecule - -[Term] -id: CHEBI:60164 -name: ionic polymer -namespace: chebi_ontology -def: "An ionic polymer is a polymer, composed of ionic macromolecules." [] -subset: 3_STAR -synonym: "polyionic polymer" RELATED [ChEBI] -is_a: CHEBI:60027 ! polymer -relationship: has_part CHEBI:53368 ! ionic macromolecule - -[Term] -id: CHEBI:60240 -name: divalent metal cation -namespace: chebi_ontology -def: "A metal cation with a valence of two." [] -subset: 3_STAR -synonym: "a divalent metal cation" RELATED [UniProt] -is_a: CHEBI:25213 ! metal cation -is_a: CHEBI:64641 ! divalent inorganic cation - -[Term] -id: CHEBI:60242 -name: monovalent inorganic cation -namespace: chebi_ontology -def: "An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one." [] -subset: 3_STAR -synonym: "a monovalent cation" RELATED [UniProt] -is_a: CHEBI:36915 ! inorganic cation - -[Term] -id: CHEBI:60466 -name: peptide zwitterion -namespace: chebi_ontology -def: "Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged." [] -subset: 3_STAR -synonym: "a peptide" RELATED [UniProt] -synonym: "peptide zwitterions" RELATED [ChEBI] -is_a: CHEBI:27369 ! zwitterion -relationship: is_tautomer_of CHEBI:16670 ! peptide -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R(C2H2NOR)n" xsd:string - -[Term] -id: CHEBI:60809 -name: adjuvant -namespace: chebi_ontology -def: "Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself." [] -subset: 3_STAR -synonym: "adjuvants" RELATED [ChEBI] -is_a: CHEBI:52217 ! pharmaceutical - -[Term] -id: CHEBI:60924 -name: keratan sulfate -namespace: chebi_ontology -def: "A sulfated glycosaminoglycan, a linear polymer that consists of the repeating disaccharide [3)-beta-Gal-(1->4)-beta-GlcNAc-(1->] and containing sulfo groups located at random positions." [] -subset: 3_STAR -synonym: "keratan sulfates" RELATED [ChEBI] -synonym: "keratosulfate" RELATED [SUBMITTER] -is_a: CHEBI:35722 ! sulfated glycosaminoglycan -is_a: CHEBI:37395 ! mucopolysaccharide -relationship: has_functional_parent CHEBI:29057 ! keratan - -[Term] -id: CHEBI:61073 -name: oxygen radical -namespace: chebi_ontology -def: "An inorganic radical in which a free electron resides on one or more oxygen atoms of an oxygen species." [] -subset: 3_STAR -synonym: "oxygen radicals" RELATED [ChEBI] -is_a: CHEBI:26523 ! reactive oxygen species -is_a: CHEBI:36871 ! inorganic radical - -[Term] -id: CHEBI:61115 -name: EC 3.5.1.98 (histone deacetylase) inhibitor -namespace: chebi_ontology -def: "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98)." [] -subset: 3_STAR -synonym: "EC 3.5.1.98 (histone deacetylase) inhibitors" RELATED [ChEBI] -synonym: "EC 3.5.1.98 inhibitor" RELATED [ChEBI] -synonym: "EC 3.5.1.98 inhibitors" RELATED [ChEBI] -synonym: "HDAC inhibitor" RELATED [ChEBI] -synonym: "HDAC inhibitors" RELATED [ChEBI] -synonym: "HDACi" RELATED [ChEBI] -synonym: "HDACis" RELATED [ChEBI] -synonym: "HDI" RELATED [ChEBI] -synonym: "HDIs" RELATED [ChEBI] -synonym: "histone amidohydrolase inhibitor" RELATED [ChEBI] -synonym: "histone amidohydrolase inhibitors" RELATED [ChEBI] -synonym: "histone deacetylase (EC 3.5.1.98) inhibitor" RELATED [ChEBI] -synonym: "histone deacetylase (EC 3.5.1.98) inhibitors" RELATED [ChEBI] -synonym: "histone deacetylase inhibitor" RELATED [ChEBI] -synonym: "histone deacetylase inhibitors" RELATED [ChEBI] -xref: Wikipedia:Histone_deacetylase_inhibitor -is_a: CHEBI:76807 ! EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor - -[Term] -id: CHEBI:61120 -name: nucleobase-containing molecular entity -namespace: chebi_ontology -def: "Any compound that has a nucleobase as a part." [] -subset: 3_STAR -synonym: "nucleobase-containing compound" RELATED [SUBMITTER] -synonym: "nucleobase-containing compounds" RELATED [ChEBI] -synonym: "nucleobase-containing molecular entities" RELATED [ChEBI] -is_a: CHEBI:33833 ! heteroarene -is_a: CHEBI:51143 ! nitrogen molecular entity -relationship: has_functional_parent CHEBI:18282 ! nucleobase - -[Term] -id: CHEBI:61313 -name: C21-steroid -namespace: chebi_ontology -def: "A steroid that has a structure based on a 21-carbon (pregnane) skeleton. Note that individual examples may have ring substituents at other positions and/or contain double bonds, aromatic A-rings, expanded/contracted rings etc., so the formula and mass may vary from that given for the generic structure." [] -subset: 3_STAR -synonym: "a C21-steroid" RELATED [UniProt] -is_a: CHEBI:35341 ! steroid -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C21H36" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C21H36/c1-4-15-9-11-18-17-10-8-16-7-5-6-13-20(16,2)19(17)12-14-21(15,18)3/h15-19H,4-14H2,1-3H3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "JWMFYGXQPXQEEM-UHFFFAOYSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "288.511" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "288.28170" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1CCCC2C1(C3C(CC2)C4C(CC3)(C(CC4)CC)C)C" xsd:string - -[Term] -id: CHEBI:61469 -name: polyanionic polymer -namespace: chebi_ontology -def: "A polymer, composed of polyanion macromolecules." [] -subset: 3_STAR -synonym: "polyanion" RELATED [ChEBI] -synonym: "polyanions" RELATED [ChEBI] -is_a: CHEBI:60164 ! ionic polymer -relationship: has_part CHEBI:53309 ! polyanionic macromolecule - -[Term] -id: CHEBI:62031 -name: polar amino acid zwitterion -namespace: chebi_ontology -def: "Zwitterionic form of a polar amino acid having an anionic carboxy group and a protonated amino group." [] -subset: 2_STAR -synonym: "a polar amino acid" RELATED [UniProt] -xref: MetaCyc:Polar-amino-acids {source="SUBMITTER"} -is_a: CHEBI:35238 ! amino acid zwitterion -relationship: is_tautomer_of CHEBI:26167 ! polar amino acid -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "74.059" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C(C([O-])=O)(*)[NH3+]" xsd:string - -[Term] -id: CHEBI:62488 -name: signalling molecule -namespace: chebi_ontology -def: "A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell." [] -subset: 3_STAR -synonym: "signal molecule" RELATED [ChEBI] -synonym: "signal molecules" RELATED [ChEBI] -synonym: "signaling molecule" RELATED [ChEBI] -synonym: "signaling molecules" RELATED [ChEBI] -synonym: "signalling molecules" RELATED [ChEBI] -is_a: CHEBI:33280 ! molecular messenger - -[Term] -id: CHEBI:62764 -name: reactive nitrogen species -namespace: chebi_ontology -def: "A family of nitrogen molecular entities which are highly reactive and derived from nitric oxide (.NO) and superoxide (O2.(-)) produced via the enzymatic activity of inducible nitric oxide synthase 2 (NOS2) and NADPH oxidase respectively." [] -subset: 3_STAR -synonym: "RNI" RELATED [SUBMITTER] -synonym: "RNS" RELATED [SUBMITTER] -xref: PMID:12076975 {source="SUBMITTER"} -xref: PMID:17667957 {source="SUBMITTER"} -xref: PMID:9741578 {source="SUBMITTER"} -xref: Wikipedia:Reactive_nitrogen_species -is_a: CHEBI:51143 ! nitrogen molecular entity - -[Term] -id: CHEBI:62868 -name: hepatoprotective agent -namespace: chebi_ontology -def: "Any compound that is able to prevent damage to the liver." [] -subset: 3_STAR -synonym: "antihepatotoxic agent" RELATED [ChEBI] -synonym: "hepatoprotective agents" RELATED [ChEBI] -synonym: "hepatoprotector" RELATED [ChEBI] -is_a: CHEBI:50267 ! protective agent - -[Term] -id: CHEBI:63248 -name: oxidising agent -namespace: chebi_ontology -def: "A substance that removes electrons from another reactant in a redox reaction." [] -subset: 3_STAR -synonym: "oxidant" RELATED [ChEBI] -synonym: "oxidants" RELATED [ChEBI] -synonym: "oxidiser" RELATED [ChEBI] -synonym: "oxidisers" RELATED [ChEBI] -synonym: "oxidising agents" RELATED [ChEBI] -synonym: "oxidizer" RELATED [ChEBI] -synonym: "oxidizers" RELATED [ChEBI] -synonym: "oxidizing agent" RELATED [ChEBI] -synonym: "oxidizing agents" RELATED [ChEBI] -is_a: CHEBI:51086 ! chemical role - -[Term] -id: CHEBI:63299 -name: carbohydrate derivative -namespace: chebi_ontology -def: "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds." [] -subset: 3_STAR -synonym: "carbohydrate derivatives" RELATED [ChEBI] -synonym: "derivatised carbohydrate" RELATED [ChEBI] -synonym: "derivatised carbohydrates" RELATED [ChEBI] -synonym: "derivatized carbohydrate" RELATED [ChEBI] -synonym: "derivatized carbohydrates" RELATED [ChEBI] -is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives -relationship: has_functional_parent CHEBI:16646 ! carbohydrate - -[Term] -id: CHEBI:63436 -name: carbohydrate acid derivative -namespace: chebi_ontology -def: "A carbohydrate derivative that is formally obtained from a carbohydrate acid." [] -subset: 3_STAR -synonym: "carbohydrate acid derivatives" RELATED [ChEBI] -is_a: CHEBI:63299 ! carbohydrate derivative -relationship: has_functional_parent CHEBI:33720 ! carbohydrate acid -relationship: is_conjugate_acid_of CHEBI:63551 ! carbohydrate acid derivative anion - -[Term] -id: CHEBI:63534 -name: monoamine -namespace: chebi_ontology -def: "An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes." [] -subset: 3_STAR -synonym: "monoamines" RELATED [ChEBI] -synonym: "naturally occurring monoamine" RELATED [ChEBI] -synonym: "naturally occurring monoamines" RELATED [ChEBI] -xref: PMID:21822758 {source="Europe PMC"} -xref: PMID:21993877 {source="Europe PMC"} -xref: PMID:22005599 {source="Europe PMC"} -xref: PMID:22082101 {source="Europe PMC"} -xref: PMID:22153577 {source="Europe PMC"} -xref: PMID:22213370 {source="Europe PMC"} -xref: PMID:22218931 {source="Europe PMC"} -xref: PMID:22342987 {source="Europe PMC"} -xref: PMID:22371656 {source="Europe PMC"} -is_a: CHEBI:64365 ! aralkylamino compound - -[Term] -id: CHEBI:63551 -name: carbohydrate acid derivative anion -namespace: chebi_ontology -def: "A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative." [] -subset: 3_STAR -synonym: "carbohydrate acid anion derivative" RELATED [ChEBI] -synonym: "carbohydrate acid anion derivatives" RELATED [ChEBI] -synonym: "carbohydrate acid derivative anions" RELATED [ChEBI] -is_a: CHEBI:29067 ! carboxylic acid anion -relationship: has_functional_parent CHEBI:33721 ! carbohydrate acid anion -relationship: is_conjugate_base_of CHEBI:63436 ! carbohydrate acid derivative - -[Term] -id: CHEBI:64047 -name: food additive -namespace: chebi_ontology -def: "Any substance which is added to food to preserve or enhance its flavour and/or appearance." [] -subset: 3_STAR -synonym: "food additives" RELATED [ChEBI] -xref: Wikipedia:Food_additive -is_a: CHEBI:33232 ! application -is_a: CHEBI:78295 ! food component - -[Term] -id: CHEBI:64049 -name: food acidity regulator -namespace: chebi_ontology -def: "A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents." [] -subset: 3_STAR -synonym: "acidity regulator" RELATED [ChEBI] -synonym: "acidity regulators" RELATED [ChEBI] -synonym: "food acidity regulators" RELATED [ChEBI] -synonym: "pH control agent" RELATED [ChEBI] -synonym: "pH control agents" RELATED [ChEBI] -xref: Wikipedia:Acidity_regulator -is_a: CHEBI:64047 ! food additive - -[Term] -id: CHEBI:64365 -name: aralkylamino compound -namespace: chebi_ontology -def: "An organic amino compound in which an aminoalkyl group is linked to an arene." [] -subset: 3_STAR -synonym: "aralkylamino compounds" RELATED [ChEBI] -is_a: CHEBI:50047 ! organic amino compound - -[Term] -id: CHEBI:64570 -name: EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor -namespace: chebi_ontology -def: "An EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor that interferes with the action of glycine hydroxymethyltransferase (EC 2.1.2.1)." [] -subset: 3_STAR -synonym: "5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase inhibitor" RELATED [ChEBI] -synonym: "5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase inhibitors" RELATED [ChEBI] -synonym: "allothreonine aldolase inhibitor" RELATED [ChEBI] -synonym: "allothreonine aldolase inhibitors" RELATED [ChEBI] -synonym: "EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitors" RELATED [ChEBI] -synonym: "EC 2.1.2.1 inhibitor" RELATED [ChEBI] -synonym: "EC 2.1.2.1 inhibitors" RELATED [ChEBI] -synonym: "glycine hydroxymethyltransferase (EC 2.1.2.1) inhibitor" RELATED [ChEBI] -synonym: "glycine hydroxymethyltransferase (EC 2.1.2.1) inhibitors" RELATED [ChEBI] -synonym: "glycine hydroxymethyltransferase inhibitor" RELATED [ChEBI] -synonym: "glycine hydroxymethyltransferase inhibitors" RELATED [ChEBI] -synonym: "L-serine hydroxymethyltransferase inhibitor" RELATED [ChEBI] -synonym: "L-serine hydroxymethyltransferase inhibitors" RELATED [ChEBI] -synonym: "L-threonine aldolase inhibitor" RELATED [ChEBI] -synonym: "L-threonine aldolase inhibitors" RELATED [ChEBI] -synonym: "serine aldolase inhibitor" RELATED [ChEBI] -synonym: "serine aldolase inhibitors" RELATED [ChEBI] -synonym: "serine hydroxymethylase inhibitor" RELATED [ChEBI] -synonym: "serine hydroxymethylase inhibitors" RELATED [ChEBI] -synonym: "serine hydroxymethyltransferase inhibitor" RELATED [ChEBI] -synonym: "serine hydroxymethyltransferase inhibitors" RELATED [ChEBI] -synonym: "serine transhydroxymethylase inhibitor" RELATED [ChEBI] -synonym: "serine transhydroxymethylase inhibitors" RELATED [ChEBI] -synonym: "threonine aldolase inhibitor" RELATED [ChEBI] -synonym: "threonine aldolase inhibitors" RELATED [ChEBI] -xref: Wikipedia:Glycine_hydroxymethyltransferase -is_a: CHEBI:76874 ! EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor - -[Term] -id: CHEBI:64571 -name: NMDA receptor agonist -namespace: chebi_ontology -def: "An excitatory amino acid agonist which binds to NMDA receptors and triggers a response." [] -subset: 3_STAR -synonym: "N-methyl-D-aspartate receptor agonist" RELATED [ChEBI] -synonym: "N-methyl-D-aspartate receptor agonists" RELATED [ChEBI] -synonym: "NMDA receptor agonists" RELATED [ChEBI] -synonym: "NMDAR agonist" RELATED [ChEBI] -synonym: "NMDAR agonists" RELATED [ChEBI] -is_a: CHEBI:50103 ! excitatory amino acid agonist - -[Term] -id: CHEBI:64600 -name: C21-steroid hormone -namespace: chebi_ontology -def: "A steroid compound with a structure based on a 21-carbon (pregnane) skeleton that acts as a hormone." [] -subset: 3_STAR -synonym: "C21-steroid hormones" RELATED [ChEBI] -is_a: CHEBI:26764 ! steroid hormone -is_a: CHEBI:61313 ! C21-steroid - -[Term] -id: CHEBI:64628 -name: somatostatin -namespace: chebi_ontology -def: "A fourteen-membered heterodetic cyclic peptide comprising the sequence Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys cyclised by a disulfide bridge between the two Cys residues at positions 3 and 14." [] -subset: 3_STAR -synonym: "Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys]" RELATED [ChEBI] -synonym: "L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide" EXACT IUPAC_NAME [IUPAC] -synonym: "L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide" RELATED [ChemIDplus] -synonym: "somatostatin" RELATED INN [KEGG_DRUG] -synonym: "Somatostatin-1" RELATED [KEGG_COMPOUND] -synonym: "Somatostatin-14" RELATED [KEGG_COMPOUND] -synonym: "somatostatina" RELATED INN [ChemIDplus] -synonym: "somatostatine" RELATED INN [ChemIDplus] -synonym: "somatostatinum" RELATED INN [ChemIDplus] -synonym: "Synthetic growth hormone release-inhibiting hormone" RELATED [ChemIDplus] -xref: CAS:38916-34-6 {source="KEGG DRUG"} -xref: CAS:38916-34-6 {source="ChemIDplus"} -xref: Drug_Central:2997 {source="DrugCentral"} -xref: HMDB:HMDB0013072 -xref: KEGG:C16022 -xref: KEGG:D07431 -xref: LINCS:LSM-5326 -xref: PMID:21922516 {source="Europe PMC"} -xref: PMID:22129035 {source="Europe PMC"} -xref: PMID:22147011 {source="Europe PMC"} -xref: PMID:22251942 {source="Europe PMC"} -xref: PMID:22483686 {source="Europe PMC"} -xref: PMID:22509294 {source="Europe PMC"} -xref: Reaxys:10148626 {source="Reaxys"} -xref: Wikipedia:Somatostatin -is_a: CHEBI:24533 ! heterodetic cyclic peptide -is_a: CHEBI:25905 ! peptide hormone -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C76H104N18O19S2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NHXLMOGPVYXJNR-ATOGVRKGSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "1637.87800" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "1636.71666" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N" xsd:string - -[Term] -id: CHEBI:64641 -name: divalent inorganic cation -namespace: chebi_ontology -def: "An inorganic cation with a valency of two." [] -subset: 3_STAR -is_a: CHEBI:36915 ! inorganic cation - -[Term] -id: CHEBI:64708 -name: one-carbon compound -namespace: chebi_ontology -def: "An organic molecular entity containing a single carbon atom (C1)." [] -subset: 3_STAR -synonym: "one-carbon compounds" RELATED [ChEBI] -is_a: CHEBI:50860 ! organic molecular entity - -[Term] -id: CHEBI:64709 -name: organic acid -namespace: chebi_ontology -def: "Any organic molecular entity that is acidic and contains carbon in covalent linkage." [] -subset: 3_STAR -synonym: "organic acids" RELATED [ChEBI] -is_a: CHEBI:50860 ! organic molecular entity - -[Term] -id: CHEBI:64909 -name: poison -namespace: chebi_ontology -def: "Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism." [] -subset: 3_STAR -synonym: "poisonous agent" RELATED [ChEBI] -synonym: "poisonous agents" RELATED [ChEBI] -synonym: "poisonous substance" RELATED [ChEBI] -synonym: "poisonous substances" RELATED [ChEBI] -synonym: "poisons" RELATED [ChEBI] -synonym: "toxic agent" RELATED [ChEBI] -synonym: "toxic agents" RELATED [ChEBI] -synonym: "toxic substance" RELATED [ChEBI] -synonym: "toxic substances" RELATED [ChEBI] -xref: Wikipedia:Poison -is_a: CHEBI:24432 ! biological role - -[Term] -id: CHEBI:6495 -name: lipoprotein -namespace: chebi_ontology -def: "A clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids." [] -subset: 3_STAR -synonym: "Lipoprotein" EXACT [KEGG_COMPOUND] -synonym: "lipoprotein particle" RELATED [ChEBI] -synonym: "lipoproteins" EXACT IUPAC_NAME [IUPAC] -xref: KEGG:C01834 -is_a: CHEBI:33837 ! conjugated protein -is_a: CHEBI:39024 ! clathrate compound -relationship: has_part CHEBI:39015 ! apolipoprotein -relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite - -[Term] -id: CHEBI:65212 -name: polysaccharide derivative -namespace: chebi_ontology -def: "A carbohydrate derivative that is any derivative of a polysaccharide." [] -subset: 3_STAR -synonym: "polysaccharide derivatives" RELATED [ChEBI] -is_a: CHEBI:167559 ! glycan -is_a: CHEBI:33694 ! biomacromolecule -is_a: CHEBI:63299 ! carbohydrate derivative -relationship: has_functional_parent CHEBI:18154 ! polysaccharide - -[Term] -id: CHEBI:65255 -name: food preservative -namespace: chebi_ontology -def: "Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes." [] -subset: 3_STAR -synonym: "food preservatives" RELATED [ChEBI] -is_a: CHEBI:64047 ! food additive - -[Term] -id: CHEBI:65256 -name: antimicrobial food preservative -namespace: chebi_ontology -def: "A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299)." [] -subset: 3_STAR -synonym: "antimicrobial food preservatives" RELATED [ChEBI] -synonym: "antimicrobial preservative" RELATED [ChEBI] -synonym: "antimicrobial preservatives" RELATED [ChEBI] -is_a: CHEBI:33281 ! antimicrobial agent -is_a: CHEBI:65255 ! food preservative - -[Term] -id: CHEBI:65296 -name: primary ammonium ion -namespace: chebi_ontology -def: "An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3." [] -subset: 3_STAR -synonym: "a primary amine" RELATED [UniProt] -synonym: "substituted ammonium" RELATED [ChEBI] -is_a: CHEBI:25697 ! organic cation -is_a: CHEBI:35274 ! ammonium ion derivative -relationship: is_conjugate_acid_of CHEBI:50994 ! primary amino compound -property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "H3NR" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "17.031" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "17.02655" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+][*]" xsd:string - -[Term] -id: CHEBI:67079 -name: anti-inflammatory agent -namespace: chebi_ontology -def: "Any compound that has anti-inflammatory effects." [] -subset: 3_STAR -synonym: "anti-inflammatory agents" RELATED [ChEBI] -synonym: "antiinflammatory agent" RELATED [ChEBI] -synonym: "antiinflammatory agents" RELATED [ChEBI] -is_a: CHEBI:33232 ! application - -[Term] -id: CHEBI:68452 -name: azole -namespace: chebi_ontology -def: "Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen." [] -subset: 3_STAR -synonym: "azoles" RELATED [ChEBI] -xref: Wikipedia:Azole -is_a: CHEBI:38101 ! organonitrogen heterocyclic compound -is_a: CHEBI:38179 ! monocyclic heteroarene - -[Term] -id: CHEBI:68495 -name: apoptosis inducer -namespace: chebi_ontology -def: "Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms." [] -subset: 3_STAR -synonym: "apoptosis inducers" RELATED [ChEBI] -synonym: "Type I cell-death inducer" RELATED [ChEBI] -synonym: "Type I cell-death inducers" RELATED [ChEBI] -synonym: "Type I programmed cell-death inducer" RELATED [ChEBI] -synonym: "Type I programmed cell-death inducers" RELATED [ChEBI] -is_a: CHEBI:52206 ! biochemical role - -[Term] -id: CHEBI:70709 -name: progesterone receptor agonist -namespace: chebi_ontology -def: "A hormone agonist that binds to and activates progesterone receptors." [] -subset: 3_STAR -synonym: "PR agonist" RELATED [ChEBI] -synonym: "PR agonists" RELATED [ChEBI] -synonym: "progesterone receptor agonists" RELATED [ChEBI] -is_a: CHEBI:51060 ! hormone agonist - -[Term] -id: CHEBI:71300 -name: EC 2.* (transferase) inhibitor -namespace: chebi_ontology -def: "An enzyme inhibitor that inhibits the action of a transferase (EC 2.*)" [] -subset: 3_STAR -synonym: "EC 2 inhibitor" RELATED [ChEBI] -synonym: "EC 2 inhibitors" RELATED [ChEBI] -synonym: "EC 2.* (transferase) inhibitors" RELATED [ChEBI] -synonym: "EC 2.* inhibitor" RELATED [ChEBI] -synonym: "EC 2.* inhibitors" RELATED [ChEBI] -synonym: "transferase inhibitor" RELATED [ChEBI] -synonym: "transferase inhibitors" RELATED [ChEBI] -xref: Wikipedia:Transferase -is_a: CHEBI:23924 ! enzyme inhibitor - -[Term] -id: CHEBI:71666 -name: gamma-amino acid anion -namespace: chebi_ontology -def: "An amino-acid anion in which the amino group is situated gamma- to the carboxylate group." [] -subset: 3_STAR -synonym: "gamma-amino acid anions" RELATED [ChEBI] -is_a: CHEBI:37022 ! amino-acid anion -relationship: is_conjugate_base_of CHEBI:33707 ! gamma-amino acid - -[Term] -id: CHEBI:72587 -name: (R)-noradrenaline(1+) -namespace: chebi_ontology -def: "An organic cation that is the conjugate acid of (R)-noradrenaline, obtained by protonation of the priamry amino group; major species at pH 7.3." [] -subset: 3_STAR -synonym: "(2R)-2-(3,4-dihydroxyphenyl)-2-hydroxyethanaminium" EXACT IUPAC_NAME [IUPAC] -synonym: "(R)-noradrenaline" RELATED [UniProt] -synonym: "(R)-noradrenaline cation" RELATED [ChEBI] -synonym: "(R)-noradrenalinium cation" RELATED [ChEBI] -synonym: "(R)-noradrenalinium(1+)" RELATED [ChEBI] -xref: PDBeChem:E5E -is_a: CHEBI:166902 ! noradrenaline(1+) -relationship: is_conjugate_acid_of CHEBI:18357 ! (R)-noradrenaline -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H12NO3" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1/t8-/m0/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-QMMMGPOBSA-O" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "170.187" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "170.08117" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C=1(C=CC(=CC1O)[C@H](C[NH3+])O)O" xsd:string - -[Term] -id: CHEBI:72695 -name: organic molecule -namespace: chebi_ontology -def: "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity." [] -subset: 3_STAR -synonym: "organic compound" RELATED [ChEBI] -synonym: "organic compounds" RELATED [ChEBI] -synonym: "organic molecules" RELATED [ChEBI] -is_a: CHEBI:25367 ! molecule -is_a: CHEBI:50860 ! organic molecular entity - -[Term] -id: CHEBI:72813 -name: exopolysaccharide -namespace: chebi_ontology -def: "A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment." [] -subset: 3_STAR -synonym: "exopolysaccharides" RELATED [ChEBI] -synonym: "extracellular polymeric substance" RELATED [ChEBI] -synonym: "extracellular polymeric substances" RELATED [ChEBI] -xref: MetaCyc:Exopolysaccharides -xref: PMID:11160795 {source="Europe PMC"} -xref: PMID:11785425 {source="Europe PMC"} -xref: PMID:1444258 {source="Europe PMC"} -xref: PMID:15738217 {source="Europe PMC"} -xref: PMID:16075348 {source="Europe PMC"} -xref: PMID:17440912 {source="Europe PMC"} -xref: PMID:18097339 {source="Europe PMC"} -xref: PMID:19453747 {source="Europe PMC"} -xref: PMID:20172021 {source="Europe PMC"} -xref: PMID:20631870 {source="Europe PMC"} -xref: PMID:20718297 {source="Europe PMC"} -xref: PMID:2688547 {source="Europe PMC"} -xref: PMID:6354590 {source="Europe PMC"} -xref: Wikipedia:Exopolysaccharide -xref: Wikipedia:Extracellular_polymeric_substance -is_a: CHEBI:33694 ! biomacromolecule - -[Term] -id: CHEBI:73398 -name: indole skeleton -namespace: chebi_ontology -def: "A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring." [] -subset: 3_STAR -is_a: CHEBI:73541 ! organic heterobicyclic ring -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C8N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "110.09230" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "110.00307" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1(=C(C(=C2C(=C1*)N(C(=C2*)*)*)*)*)*" xsd:string - -[Term] -id: CHEBI:73541 -name: organic heterobicyclic ring -namespace: chebi_ontology -def: "A bicyclic organic group that contains both carbon and hetero atoms." [] -subset: 3_STAR -synonym: "organic heterobicyclic rings" RELATED [ChEBI] -is_a: CHEBI:52845 ! cyclic organic group - -[Term] -id: CHEBI:74783 -name: astringent -namespace: chebi_ontology -def: "A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions." [] -subset: 3_STAR -synonym: "adstringent" RELATED [ChEBI] -synonym: "adstringents" RELATED [ChEBI] -synonym: "astringents" RELATED [ChEBI] -xref: Wikipedia:Astringent -is_a: CHEBI:23888 ! drug - -[Term] -id: CHEBI:75431 -name: ghrelin -namespace: chebi_ontology -def: "A 28-membered appetite-stimulating polypeptide consisting of Gly, Ser, Ser(octanoyl), Phe, Leu, Ser, Pro, Glu, His, Gln, Arg, Val, Gln, Gln, Arg, Lys, Glu, Ser, Lys, Lys, Pro, Pro, Ala, Lys, Leu, Gln, Pro and Arg residues joined in sequence. The O-n-octanoylation of the side-chain hydroxy group of serine-3 (Ser3) is essential for ghrelin's activity." [] -subset: 3_STAR -synonym: "Gastric MLTRP" RELATED [ChemIDplus] -synonym: "Ghrelin (human)" RELATED [ChemIDplus] -synonym: "Gly-Ser-Ser(octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg" RELATED [ChEBI] -synonym: "glycyl-L-seryl-O-octanoyl-L-seryl-L-phenylalanyl-L-leucyl-L-seryl-L-prolyl-L-alpha-glutamyl-L-histidyl-L-glutaminyl-L-arginyl-L-valyl-L-glutaminyl-L-glutaminyl-L-arginyl-L-lysyl-L-alpha-glutamyl-L-seryl-L-lysyl-L-lysyl-L-prolyl-L-prolyl-L-alanyl-L-lysyl-L-leucyl-L-glutaminyl-L-prolyl-L-arginine" EXACT IUPAC_NAME [IUPAC] -synonym: "GS-S(n-octanoyl)-FLSPEHQRVQQRKESKKPPAKLQPR" RELATED [ChEBI] -synonym: "GSS(octanoyl)FLSPEHQRVQQRKESKKPPAKLQPR" RELATED [ChEBI] -synonym: "H-Gly-Ser-Ser(n-octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg-OH" RELATED [ChEBI] -synonym: "Human ghrelin" RELATED [ChemIDplus] -synonym: "lenomorelin" RELATED INN [WHO_MedNet] -synonym: "lenomorelina" RELATED INN [WHO_MedNet] -synonym: "lenomoreline" RELATED INN [WHO_MedNet] -synonym: "lenomorelinum" RELATED INN [WHO_MedNet] -synonym: "Motilin-related peptide" RELATED [ChemIDplus] -xref: CAS:258279-04-8 {source="ChemIDplus"} -xref: CAS:304853-26-7 {source="ChemIDplus"} -xref: KEGG:C16025 -xref: PMID:15788704 {source="Europe PMC"} -xref: PMID:23159561 {source="Europe PMC"} -xref: PMID:23178701 {source="Europe PMC"} -xref: PMID:23278489 {source="Europe PMC"} -xref: PMID:23307791 {source="Europe PMC"} -xref: PMID:23316086 {source="Europe PMC"} -xref: PMID:23317782 {source="Europe PMC"} -xref: PMID:23359315 {source="Europe PMC"} -xref: PMID:23428971 {source="Europe PMC"} -xref: PMID:23481295 {source="Europe PMC"} -xref: PMID:23524619 {source="Europe PMC"} -xref: PMID:23624808 {source="Europe PMC"} -xref: PMID:23631903 {source="Europe PMC"} -xref: PMID:23652386 {source="Europe PMC"} -xref: PMID:23652399 {source="Europe PMC"} -xref: PMID:23652420 {source="Europe PMC"} -xref: PMID:23698230 {source="Europe PMC"} -xref: PMID:23704134 {source="Europe PMC"} -xref: PMID:23778458 {source="Europe PMC"} -xref: PMID:23804489 {source="Europe PMC"} -xref: PMID:23808302 {source="Europe PMC"} -xref: PMID:23843943 {source="Europe PMC"} -xref: PMID:23847595 {source="Europe PMC"} -xref: PMID:23965296 {source="Europe PMC"} -xref: PMID:23982275 {source="Europe PMC"} -xref: PMID:23989358 {source="Europe PMC"} -xref: PMID:28538835 {source="Europe PMC"} -xref: PMID:28542403 {source="Europe PMC"} -xref: PMID:28547758 {source="Europe PMC"} -xref: PMID:28590260 {source="Europe PMC"} -xref: PMID:28621678 {source="Europe PMC"} -xref: PMID:28704966 {source="Europe PMC"} -xref: Reaxys:24715767 {source="Reaxys"} -xref: Wikipedia:Ghrelin -is_a: CHEBI:15841 ! polypeptide -is_a: CHEBI:25905 ! peptide hormone -relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent -relationship: RO:0000087 CHEBI:50779 ! has role appetite enhancer -relationship: RO:0000087 CHEBI:50855 ! has role antiatherogenic agent -relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer -relationship: RO:0000087 CHEBI:77746 ! has role human metabolite -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C149H249N47O42" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C149H249N47O42/c1-9-10-11-12-16-45-118(209)238-78-106(191-135(225)103(75-197)171-115(204)73-154)137(227)187-101(71-84-32-14-13-15-33-84)133(223)186-100(70-81(4)5)132(222)190-105(77-199)144(234)194-66-29-42-108(194)139(229)180-95(51-57-117(207)208)128(218)188-102(72-85-74-165-79-169-85)134(224)179-92(47-53-112(156)201)126(216)175-90(39-26-63-167-148(161)162)130(220)192-119(82(6)7)141(231)181-93(48-54-113(157)202)127(217)177-91(46-52-111(155)200)125(215)174-89(38-25-62-166-147(159)160)122(212)173-87(35-18-22-59-151)121(211)178-94(50-56-116(205)206)129(219)189-104(76-198)136(226)176-88(36-19-23-60-152)123(213)182-96(37-20-24-61-153)142(232)196-68-31-44-110(196)145(235)195-67-30-41-107(195)138(228)170-83(8)120(210)172-86(34-17-21-58-150)124(214)185-99(69-80(2)3)131(221)183-97(49-55-114(158)203)143(233)193-65-28-43-109(193)140(230)184-98(146(236)237)40-27-64-168-149(163)164/h13-15,32-33,74,79-83,86-110,119,197-199H,9-12,16-31,34-73,75-78,150-154H2,1-8H3,(H2,155,200)(H2,156,201)(H2,157,202)(H2,158,203)(H,165,169)(H,170,228)(H,171,204)(H,172,210)(H,173,212)(H,174,215)(H,175,216)(H,176,226)(H,177,217)(H,178,211)(H,179,224)(H,180,229)(H,181,231)(H,182,213)(H,183,221)(H,184,230)(H,185,214)(H,186,223)(H,187,227)(H,188,218)(H,189,219)(H,190,222)(H,191,225)(H,192,220)(H,205,206)(H,207,208)(H,236,237)(H4,159,160,166)(H4,161,162,167)(H4,163,164,168)/t83-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,119-/m0/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "GNKDKYIHGQKHHM-RJKLHVOGSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "3370.867" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "3368.87933" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "C(C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(N1[C@@H](CCC1)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(N2[C@@H](CCC2)C(N3[C@@H](CCC3)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(N4[C@@H](CCC4)C(=O)N[C@H](C(=O)O)CCCNC(=N)N)=O)CCC(=O)N)CC(C)C)CCCCN)C)=O)=O)CCCCN)CCCCN)CO)CCC(=O)O)CCCCN)CCCNC(N)=N)CCC(=O)N)CCC(=O)N)C(C)C)CCCNC(N)=N)CCC(=O)N)CC=5N=CNC5)CCC(=O)O)=O)CO)CC(C)C)CC=6C=CC=CC6)COC(=O)CCCCCCC)CO)N" xsd:string - -[Term] -id: CHEBI:75763 -name: eukaryotic metabolite -namespace: chebi_ontology -def: "Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms." [] -subset: 3_STAR -synonym: "eukaryotic metabolites" RELATED [ChEBI] -is_a: CHEBI:25212 ! metabolite - -[Term] -id: CHEBI:75767 -name: animal metabolite -namespace: chebi_ontology -alt_id: CHEBI:77721 -alt_id: CHEBI:77743 -def: "Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals." [] -subset: 3_STAR -synonym: "animal metabolites" RELATED [ChEBI] -is_a: CHEBI:75763 ! eukaryotic metabolite - -[Term] -id: CHEBI:75768 -name: mammalian metabolite -namespace: chebi_ontology -alt_id: CHEBI:77464 -alt_id: CHEBI:77744 -def: "Any animal metabolite produced during a metabolic reaction in mammals." [] -subset: 3_STAR -synonym: "mammalian metabolites" RELATED [ChEBI] -is_a: CHEBI:75767 ! animal metabolite - -[Term] -id: CHEBI:75771 -name: mouse metabolite -namespace: chebi_ontology -def: "Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus)." [] -subset: 3_STAR -synonym: "mouse metabolites" RELATED [ChEBI] -synonym: "Mus musculus metabolite" RELATED [ChEBI] -synonym: "Mus musculus metabolites" RELATED [ChEBI] -is_a: CHEBI:75768 ! mammalian metabolite - -[Term] -id: CHEBI:75772 -name: Saccharomyces cerevisiae metabolite -namespace: chebi_ontology -alt_id: CHEBI:76949 -alt_id: CHEBI:76951 -def: "Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae)." [] -subset: 3_STAR -synonym: "baker's yeast metabolite" RELATED [ChEBI] -synonym: "baker's yeast metabolites" RELATED [ChEBI] -synonym: "baker's yeast secondary metabolite" RELATED [ChEBI] -synonym: "baker's yeast secondary metabolites" RELATED [ChEBI] -synonym: "S. cerevisiae metabolite" RELATED [ChEBI] -synonym: "S. cerevisiae metabolites" RELATED [ChEBI] -synonym: "S. cerevisiae secondary metabolite" RELATED [ChEBI] -synonym: "S. cerevisiae secondary metabolites" RELATED [ChEBI] -synonym: "Saccharomyces cerevisiae metabolites" RELATED [ChEBI] -synonym: "Saccharomyces cerevisiae secondary metabolites" RELATED [ChEBI] -is_a: CHEBI:76946 ! fungal metabolite - -[Term] -id: CHEBI:75787 -name: prokaryotic metabolite -namespace: chebi_ontology -def: "Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea." [] -subset: 3_STAR -synonym: "prokaryotic metabolites" RELATED [ChEBI] -is_a: CHEBI:25212 ! metabolite - -[Term] -id: CHEBI:76206 -name: xenobiotic metabolite -namespace: chebi_ontology -def: "Any metabolite produced by metabolism of a xenobiotic compound." [] -subset: 3_STAR -synonym: "xenobiotic metabolites" RELATED [ChEBI] -is_a: CHEBI:25212 ! metabolite - -[Term] -id: CHEBI:76413 -name: greenhouse gas -namespace: chebi_ontology -def: "A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'." [] -subset: 3_STAR -synonym: "greenhouse gases" RELATED [ChEBI] -xref: Wikipedia:Greenhouse_gas -is_a: CHEBI:51086 ! chemical role - -[Term] -id: CHEBI:76655 -name: EC 2.1.* (C1-transferase) inhibitor -namespace: chebi_ontology -def: "A transferase inhibitor inhibiting the action of transferase of a one-carbon-containing group (EC 2.1.*.*)." [] -subset: 3_STAR -synonym: "C1-transferase (EC 2.1.*) inhibitor" RELATED [ChEBI] -synonym: "C1-transferase (EC 2.1.*) inhibitors" RELATED [ChEBI] -synonym: "C1-transferase inhibitor" RELATED [ChEBI] -synonym: "C1-transferase inhibitors" RELATED [ChEBI] -synonym: "EC 2.1.* (C1-transferase) inhibitors" RELATED [ChEBI] -synonym: "EC 2.1.* inhibitor" RELATED [ChEBI] -synonym: "EC 2.1.* inhibitors" RELATED [ChEBI] -synonym: "one-carbon-containing group transferase inhibitor" RELATED [ChEBI] -synonym: "one-carbon-containing group transferase inhibitors" RELATED [ChEBI] -is_a: CHEBI:71300 ! EC 2.* (transferase) inhibitor - -[Term] -id: CHEBI:76759 -name: EC 3.* (hydrolase) inhibitor -namespace: chebi_ontology -def: "Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*)." [] -subset: 3_STAR -synonym: "EC 3.* (hydrolase) inhibitors" RELATED [ChEBI] -synonym: "EC 3.* inhibitor" RELATED [ChEBI] -synonym: "EC 3.* inhibitors" RELATED [ChEBI] -synonym: "EC 3.*.*.* inhibitor" RELATED [ChEBI] -synonym: "EC 3.*.*.* inhibitors" RELATED [ChEBI] -synonym: "hydrolase (EC 3.*) inhibitor" RELATED [ChEBI] -synonym: "hydrolase (EC 3.*) inhibitors" RELATED [ChEBI] -synonym: "hydrolase inhibitor" RELATED [ChEBI] -synonym: "hydrolase inhibitors" RELATED [ChEBI] -xref: Wikipedia:Hydrolase -is_a: CHEBI:23924 ! enzyme inhibitor - -[Term] -id: CHEBI:76764 -name: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor -namespace: chebi_ontology -def: "Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*)." [] -subset: 3_STAR -synonym: "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor" RELATED [ChEBI] -synonym: "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors" RELATED [ChEBI] -synonym: "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor" RELATED [ChEBI] -synonym: "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors" RELATED [ChEBI] -synonym: "EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors" RELATED [ChEBI] -synonym: "EC 3.5.* inhibitor" RELATED [ChEBI] -synonym: "EC 3.5.* inhibitors" RELATED [ChEBI] -is_a: CHEBI:76759 ! EC 3.* (hydrolase) inhibitor - -[Term] -id: CHEBI:76807 -name: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor -namespace: chebi_ontology -def: "An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*)." [] -subset: 3_STAR -synonym: "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors" RELATED [ChEBI] -synonym: "EC 3.5.1.* inhibitor" RELATED [ChEBI] -synonym: "EC 3.5.1.* inhibitors" RELATED [ChEBI] -synonym: "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor" RELATED [ChEBI] -synonym: "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors" RELATED [ChEBI] -is_a: CHEBI:76764 ! EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor - -[Term] -id: CHEBI:76874 -name: EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor -namespace: chebi_ontology -def: "An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any hydroxymethyl-, formyl- and related transferase (EC 2.1.2.*)." [] -subset: 3_STAR -synonym: "EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitors" RELATED [ChEBI] -synonym: "EC 2.1.2.* inhibitor" RELATED [ChEBI] -synonym: "EC 2.1.2.* inhibitors" RELATED [ChEBI] -synonym: "hydroxymethyl-, formyl- and related transferases (EC 2.1.2.*) inhibitor" RELATED [ChEBI] -synonym: "hydroxymethyl-, formyl- and related transferases (EC 2.1.2.*) inhibitors" RELATED [ChEBI] -is_a: CHEBI:76655 ! EC 2.1.* (C1-transferase) inhibitor - -[Term] -id: CHEBI:76924 -name: plant metabolite -namespace: chebi_ontology -alt_id: CHEBI:75766 -alt_id: CHEBI:76925 -def: "Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms." [] -subset: 3_STAR -synonym: "plant metabolites" RELATED [ChEBI] -synonym: "plant secondary metabolites" RELATED [ChEBI] -is_a: CHEBI:75763 ! eukaryotic metabolite - -[Term] -id: CHEBI:76946 -name: fungal metabolite -namespace: chebi_ontology -alt_id: CHEBI:75765 -alt_id: CHEBI:76947 -def: "Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds." [] -subset: 3_STAR -synonym: "fungal metabolites" RELATED [ChEBI] -is_a: CHEBI:75763 ! eukaryotic metabolite - -[Term] -id: CHEBI:76967 -name: human xenobiotic metabolite -namespace: chebi_ontology -def: "Any human metabolite produced by metabolism of a xenobiotic compound in humans." [] -subset: 3_STAR -synonym: "human xenobiotic metabolites" RELATED [ChEBI] -is_a: CHEBI:76206 ! xenobiotic metabolite -is_a: CHEBI:77746 ! human metabolite - -[Term] -id: CHEBI:76969 -name: bacterial metabolite -namespace: chebi_ontology -alt_id: CHEBI:75760 -alt_id: CHEBI:76970 -def: "Any prokaryotic metabolite produced during a metabolic reaction in bacteria." [] -subset: 3_STAR -is_a: CHEBI:75787 ! prokaryotic metabolite - -[Term] -id: CHEBI:76971 -name: Escherichia coli metabolite -namespace: chebi_ontology -def: "Any bacterial metabolite produced during a metabolic reaction in Escherichia coli." [] -subset: 3_STAR -synonym: "E.coli metabolite" RELATED [ChEBI] -synonym: "E.coli metabolites" RELATED [ChEBI] -synonym: "Escherichia coli metabolites" RELATED [ChEBI] -is_a: CHEBI:76969 ! bacterial metabolite - -[Term] -id: CHEBI:77746 -name: human metabolite -namespace: chebi_ontology -alt_id: CHEBI:75770 -alt_id: CHEBI:77123 -def: "Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens)." [] -subset: 3_STAR -synonym: "H. sapiens metabolite" RELATED [ChEBI] -synonym: "H. sapiens metabolites" RELATED [ChEBI] -synonym: "Homo sapiens metabolite" RELATED [ChEBI] -synonym: "Homo sapiens metabolites" RELATED [ChEBI] -is_a: CHEBI:75768 ! mammalian metabolite - -[Term] -id: CHEBI:77941 -name: EC 3.5.1.4 (amidase) inhibitor -namespace: chebi_ontology -def: "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4)." [] -subset: 3_STAR -synonym: "acylamidase inhibitor" RELATED [ChEBI] -synonym: "acylamidase inhibitors" RELATED [ChEBI] -synonym: "acylamide amidohydrolase inhibitor" RELATED [ChEBI] -synonym: "acylamide amidohydrolase inhibitors" RELATED [ChEBI] -synonym: "amidase (EC 3.5.1.4) inhibitor" RELATED [ChEBI] -synonym: "amidase (EC 3.5.1.4) inhibitors" RELATED [ChEBI] -synonym: "amidase inhibitor" RELATED [ChEBI] -synonym: "amidase inhibitors" RELATED [ChEBI] -synonym: "amidohydrolase inhibitor" RELATED [ChEBI] -synonym: "amidohydrolase inhibitors" RELATED [ChEBI] -synonym: "deaminase inhibitor" RELATED [ChEBI] -synonym: "deaminase inhibitors" RELATED [ChEBI] -synonym: "EC 3.5.1.4 (amidase) inhibitors" RELATED [ChEBI] -synonym: "EC 3.5.1.4 inhibitor" RELATED [ChEBI] -synonym: "EC 3.5.1.4 inhibitors" RELATED [ChEBI] -synonym: "fatty acylamidase inhibitor" RELATED [ChEBI] -synonym: "fatty acylamidase inhibitors" RELATED [ChEBI] -synonym: "N-acetylaminohydrolase inhibitor" RELATED [ChEBI] -synonym: "N-acetylaminohydrolase inhibitors" RELATED [ChEBI] -xref: Wikipedia:Amidase -is_a: CHEBI:76807 ! EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor - -[Term] -id: CHEBI:77974 -name: food packaging gas -namespace: chebi_ontology -def: "A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container." [] -subset: 3_STAR -synonym: "food packaging gases" RELATED [ChEBI] -xref: Wikipedia:Packaging_gas -is_a: CHEBI:64047 ! food additive - -[Term] -id: CHEBI:78115 -name: fatty acid anion 4:0 -namespace: chebi_ontology -def: "Any saturated fatty acid anion containing 4 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." [] -subset: 3_STAR -synonym: "fatty acid 4:0" RELATED [UniProt] -is_a: CHEBI:58951 ! short-chain fatty acid anion -is_a: CHEBI:58953 ! saturated fatty acid anion -relationship: is_conjugate_base_of CHEBI:140601 ! fatty acid 4:0 -property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H7O2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "87.09718" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "87.04460" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([*])=O" xsd:string - -[Term] -id: CHEBI:78295 -name: food component -namespace: chebi_ontology -def: "A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants." [] -subset: 3_STAR -synonym: "dietary component" RELATED [ChEBI] -synonym: "dietary components" RELATED [ChEBI] -synonym: "food components" RELATED [ChEBI] -is_a: CHEBI:52211 ! physiological role - -[Term] -id: CHEBI:78433 -name: refrigerant -namespace: chebi_ontology -def: "A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a \"R\" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure." [] -subset: 3_STAR -synonym: "refrigerants" RELATED [ChEBI] -xref: Wikipedia:Refrigerant -is_a: CHEBI:33232 ! application - -[Term] -id: CHEBI:78608 -name: alpha-amino acid zwitterion -namespace: chebi_ontology -alt_id: CHEBI:83409 -def: "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3." [] -subset: 3_STAR -synonym: "an alpha-amino acid" RELATED [UniProt] -xref: MetaCyc:Alpha-Amino-Acids {source="SUBMITTER"} -is_a: CHEBI:35238 ! amino acid zwitterion -relationship: is_tautomer_of CHEBI:33704 ! alpha-amino acid -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "74.059" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]C([*])C([O-])=O" xsd:string - -[Term] -id: CHEBI:78616 -name: carbohydrates and carbohydrate derivatives -namespace: chebi_ontology -def: "Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation." [] -subset: 3_STAR -synonym: "carbohydrates and derivatives" RELATED [ChEBI] -synonym: "carbohydrates and their derivatives" RELATED [ChEBI] -is_a: CHEBI:36963 ! organooxygen compound - -[Term] -id: CHEBI:78675 -name: fundamental metabolite -namespace: chebi_ontology -def: "Any metabolite produced by all living cells." [] -subset: 3_STAR -synonym: "essential metabolite" RELATED [ChEBI] -synonym: "essential metabolites" RELATED [ChEBI] -synonym: "fundamental metabolites" RELATED [ChEBI] -is_a: CHEBI:25212 ! metabolite - -[Term] -id: CHEBI:7872 -name: oxytocin -namespace: chebi_ontology -def: "A cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG that also acts as a neurotransmitter in the brain; the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary. Together with the neuropeptide vasopressin, it is believed to influence social cognition and behaviour." [] -subset: 3_STAR -synonym: "(1-Hemicystine)oxytocin" RELATED [ChemIDplus] -synonym: "1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide" EXACT IUPAC_NAME [IUPAC] -synonym: "3-Isoleucine-8-leucine vasopressin" RELATED [ChemIDplus] -synonym: "Endopituitrina" RELATED [ChemIDplus] -synonym: "L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic(1-6)-disulfide" RELATED [ChemIDplus] -synonym: "Ocytocin" RELATED [KEGG_COMPOUND] -synonym: "Orasthin" RELATED BRAND_NAME [ChemIDplus] -synonym: "OT" RELATED [KEGG_COMPOUND] -synonym: "oxitocina" RELATED INN [ChemIDplus] -synonym: "OXT" RELATED [KEGG_COMPOUND] -synonym: "Oxytocin" EXACT [KEGG_COMPOUND] -synonym: "oxytocin" RELATED INN [ChemIDplus] -synonym: "oxytocine" RELATED INN [ChemIDplus] -synonym: "oxytocinum" RELATED INN [ChemIDplus] -synonym: "Pitocin" RELATED BRAND_NAME [DrugBank] -synonym: "Piton S" RELATED BRAND_NAME [ChemIDplus] -synonym: "Syntocinon" RELATED BRAND_NAME [DrugBank] -synonym: "Syntocinon" RELATED BRAND_NAME [ChemIDplus] -xref: Beilstein:3586108 {source="Beilstein"} -xref: CAS:50-56-6 {source="ChemIDplus"} -xref: Drug_Central:2042 {source="DrugCentral"} -xref: DrugBank:DB00107 -xref: HMDB:HMDB0002865 -xref: KEGG:C00746 -xref: KEGG:D00089 -xref: Patent:US2938891 -xref: Patent:US3076797 -xref: PMID:10027619 {source="Europe PMC"} -xref: PMID:10834934 {source="Europe PMC"} -xref: PMID:10949083 {source="Europe PMC"} -xref: PMID:10949750 {source="Europe PMC"} -xref: PMID:10983343 {source="Europe PMC"} -xref: PMID:11134819 {source="Europe PMC"} -xref: PMID:13305558 {source="Europe PMC"} -xref: PMID:15815422 {source="Europe PMC"} -xref: PMID:18593851 {source="Europe PMC"} -xref: PMID:18988842 {source="Europe PMC"} -xref: PMID:19104313 {source="Europe PMC"} -xref: PMID:19369205 {source="Europe PMC"} -xref: PMID:19482229 {source="Europe PMC"} -xref: PMID:24706799 {source="Europe PMC"} -xref: PMID:25209411 {source="Europe PMC"} -xref: PMID:32509991 {source="Europe PMC"} -xref: PMID:32683141 {source="Europe PMC"} -xref: PMID:32979349 {source="Europe PMC"} -xref: PMID:33192340 {source="Europe PMC"} -xref: Wikipedia:Oxytocin -is_a: CHEBI:24533 ! heterodetic cyclic peptide -is_a: CHEBI:25905 ! peptide hormone -relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent -relationship: RO:0000087 CHEBI:36063 ! has role oxytocic -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C43H66N12O12S2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C43H66N12O12S2/c1-5-22(4)35-42(66)49-26(12-13-32(45)57)38(62)51-29(17-33(46)58)39(63)53-30(20-69-68-19-25(44)36(60)50-28(40(64)54-35)16-23-8-10-24(56)11-9-23)43(67)55-14-6-7-31(55)41(65)52-27(15-21(2)3)37(61)48-18-34(47)59/h8-11,21-22,25-31,35,56H,5-7,12-20,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,48,61)(H,49,66)(H,50,60)(H,51,62)(H,52,65)(H,53,63)(H,54,64)/t22-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "XNOPRXBHLZRZKH-DSZYJQQASA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "1007.18982" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "1006.43646" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@]1(NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)[C@@H](C)CC" xsd:string - -[Term] -id: CHEBI:78840 -name: olefinic compound -namespace: chebi_ontology -def: "Any organic molecular entity that contains at least one C=C bond." [] -subset: 3_STAR -synonym: "olefinic compounds" RELATED [ChEBI] -is_a: CHEBI:50860 ! organic molecular entity - -[Term] -id: CHEBI:79387 -name: trivalent inorganic anion -namespace: chebi_ontology -def: "Any inorganic anion with a valency of three." [] -subset: 3_STAR -synonym: "trivalent inorganic anions" RELATED [ChEBI] -is_a: CHEBI:24834 ! inorganic anion - -[Term] -id: CHEBI:79388 -name: divalent inorganic anion -namespace: chebi_ontology -def: "Any inorganic anion with a valency of two." [] -subset: 3_STAR -synonym: "divalent inorganic anions" RELATED [ChEBI] -is_a: CHEBI:24834 ! inorganic anion - -[Term] -id: CHEBI:79389 -name: monovalent inorganic anion -namespace: chebi_ontology -def: "Any inorganic anion with a valency of one." [] -subset: 3_STAR -synonym: "monovalent inorganic anions" RELATED [ChEBI] -is_a: CHEBI:24834 ! inorganic anion - -[Term] -id: CHEBI:82663 -name: elemental iron -namespace: chebi_ontology -def: "An elemental molecular entity in which all of the atoms have atomic number 26." [] -subset: 3_STAR -is_a: CHEBI:24873 ! iron molecular entity -is_a: CHEBI:33259 ! elemental molecular entity - -[Term] -id: CHEBI:83039 -name: crustacean metabolite -namespace: chebi_ontology -def: "An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill." [] -subset: 3_STAR -synonym: "crustacean metabolites" RELATED [ChEBI] -is_a: CHEBI:75767 ! animal metabolite - -[Term] -id: CHEBI:83056 -name: Daphnia magna metabolite -namespace: chebi_ontology -def: "A Daphnia metabolite produced by the species Daphnia magna." [] -subset: 3_STAR -synonym: "Daphnia magna metabolites" RELATED [ChEBI] -is_a: CHEBI:83057 ! Daphnia metabolite - -[Term] -id: CHEBI:83057 -name: Daphnia metabolite -namespace: chebi_ontology -def: "A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia" [] -subset: 3_STAR -synonym: "Daphnia metabolites" RELATED [ChEBI] -xref: Wikipedia:Daphnia -is_a: CHEBI:83039 ! crustacean metabolite - -[Term] -id: CHEBI:83813 -name: proteinogenic amino acid -namespace: chebi_ontology -def: "Any of the 23 alpha-amino acids that are precursors to proteins, and are incorporated into proteins during translation. The group includes the 20 amino acids encoded by the nuclear genes of eukaryotes together with selenocysteine, pyrrolysine, and N-formylmethionine. Apart from glycine, which is non-chiral, all have L configuration." [] -subset: 3_STAR -synonym: "canonical amino acid" RELATED [ChEBI] -synonym: "canonical amino acids" RELATED [ChEBI] -synonym: "proteinogenic amino acids" RELATED [ChEBI] -xref: Wikipedia:Proteinogenic_amino_acid -is_a: CHEBI:33575 ! carboxylic acid -is_a: CHEBI:35352 ! organonitrogen compound - -[Term] -id: CHEBI:83820 -name: non-proteinogenic amino acid -namespace: chebi_ontology -def: "Any amino-acid that is not naturally encoded in the genetic code of any organism." [] -subset: 3_STAR -synonym: "non-canonical amino acid" RELATED [ChEBI] -synonym: "non-canonical amino acids" RELATED [ChEBI] -synonym: "non-canonical amino-acid" RELATED [ChEBI] -synonym: "non-canonical amino-acids" RELATED [ChEBI] -synonym: "non-coded amino acid" RELATED [ChEBI] -synonym: "non-coded amino acids" RELATED [ChEBI] -synonym: "non-coded amino-acid" RELATED [ChEBI] -synonym: "non-coded amino-acids" RELATED [ChEBI] -synonym: "non-proteinogenic amino acids" RELATED [ChEBI] -synonym: "non-proteinogenic amino-acid" RELATED [ChEBI] -synonym: "non-proteinogenic amino-acids" RELATED [ChEBI] -xref: Wikipedia:Non-proteinogenic_amino_acids -is_a: CHEBI:33709 ! amino acid - -[Term] -id: CHEBI:83821 -name: amino acid derivative -namespace: chebi_ontology -alt_id: CHEBI:25359 -def: "Any derivative of an amino acid resulting from reaction at an amino group, carboxy group, side-chain functional group, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing amino acid residues." [] -subset: 3_STAR -synonym: "amino acid derivatives" RELATED [ChEBI] -synonym: "modified amino acids" RELATED [ChEBI] -is_a: CHEBI:35352 ! organonitrogen compound - -[Term] -id: CHEBI:8386 -name: pregnane -namespace: chebi_ontology -subset: 3_STAR -synonym: "pregnane" EXACT IUPAC_NAME [IUPAC] -xref: LIPID_MAPS_instance:LMST02030000 {source="LIPID MAPS"} -xref: Wikipedia:Pregnane -is_a: CHEBI:35508 ! steroid fundamental parent -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C21H36" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C21H36/c1-4-15-9-11-18-17-10-8-16-7-5-6-13-20(16,2)19(17)12-14-21(15,18)3/h15-19H,4-14H2,1-3H3/t15-,16?,17-,18-,19-,20-,21+/m0/s1" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/inchikey "JWMFYGXQPXQEEM-WZBAXQLOSA-N" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "288.51054" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "288.28170" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@]1(CC)CC[C@@]2([H])[C@]3([H])CCC4([H])CCCC[C@]4(C)[C@@]3([H])CC[C@]12C" xsd:string - -[Term] -id: CHEBI:84087 -name: human urinary metabolite -namespace: chebi_ontology -def: "Any metabolite (endogenous or exogenous) found in human urine samples." [] -subset: 3_STAR -synonym: "human urinary metabolites" RELATED [ChEBI] -is_a: CHEBI:77746 ! human metabolite - -[Term] -id: CHEBI:84729 -name: hydroxyindoles -namespace: chebi_ontology -def: "Any member of the class of indoles carrying at least one hydroxy group." [] -subset: 3_STAR -is_a: CHEBI:24828 ! indoles -is_a: CHEBI:33822 ! organic hydroxy compound - -[Term] -id: CHEBI:84735 -name: algal metabolite -namespace: chebi_ontology -def: "Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae." [] -subset: 3_STAR -synonym: "algal metabolites" RELATED [ChEBI] -is_a: CHEBI:75763 ! eukaryotic metabolite - -[Term] -id: CHEBI:90710 -name: receptor modulator -namespace: chebi_ontology -def: "A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors." [] -subset: 3_STAR -synonym: "receptor modulators" RELATED [ChEBI] -is_a: CHEBI:23888 ! drug - -[Term] -id: CHEBI:9937 -name: vasopressin -namespace: chebi_ontology -def: "A family of cyclic nonapeptide hormones found in most mammals. Synthesised in the hypothalamus and stored in the post-pituitary, vasopressins play a key role in homeostasis, particularly in regulating the body's water content. Together with the similar neuropeptide oxytocin, they are believed to influence social cognition and behaviour." [] -subset: 3_STAR -synonym: "ADH" RELATED [KEGG_COMPOUND] -synonym: "Antidiuretic hormone" RELATED [KEGG_COMPOUND] -synonym: "arginine vasopressin" RELATED [ChEBI] -synonym: "argipressin" RELATED [ChEBI] -synonym: "AVP" RELATED [ChEBI] -synonym: "beta-Hypophamine" RELATED [ChemIDplus] -synonym: "Inyectable de vasopresina" RELATED INN [ChemIDplus] -synonym: "Solute injectable de vasopressine" RELATED INN [ChemIDplus] -synonym: "Vasopressin" EXACT [KEGG_COMPOUND] -synonym: "Vasopressini injectio" RELATED INN [ChemIDplus] -synonym: "VP" RELATED [KEGG_COMPOUND] -xref: CAS:11000-17-2 {source="ChemIDplus"} -xref: KEGG:C00840 -xref: KEGG:D00101 -xref: PMID:18988842 {source="Europe PMC"} -xref: PMID:20445498 {source="Europe PMC"} -is_a: CHEBI:24533 ! heterodetic cyclic peptide -is_a: CHEBI:25905 ! peptide hormone -property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/formula "C46H65N15O12S2.C46H65N13O12S2" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/mass "2140.458" xsd:string -property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "2138.86956" xsd:string [Term] id: CL:0000000 @@ -11525,6 +611,7 @@ xref: MESH:D002477 xref: VHOG:0001533 xref: WBbt:0004017 xref: XAO:0003012 +is_a: UBERON:0000061 ! anatomical structure disjoint_from: GO:0031012 ! extracellular matrix disjoint_from: GO:0032991 ! protein-containing complex disjoint_from: GO:0043226 ! organelle @@ -11947,32 +1034,32 @@ is_a: CL:0011026 ! progenitor cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: capable_of GO:0002244 ! hematopoietic progenitor cell differentiation intersection_of: capable_of GO:0048103 ! somatic stem cell division -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -intersection_of: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -intersection_of: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -intersection_of: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: capable_of GO:0002244 ! hematopoietic progenitor cell differentiation +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: develops_from CL:0000566 ! angioblastic mesenchymal cell -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -relationship: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -relationship: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -relationship: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -relationship: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] @@ -11996,7 +1083,6 @@ name: germ line cell def: "A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring." [GOC:tfm, ISBN:0721662544] comment: Originally this term had some plant germ line cell children. subset: ubprop:upper_level -is_a: BFO:0000040 ! material entity is_a: CL:0000003 ! native cell disjoint_from: CL:0002371 ! somatic cell relationship: capable_of GO:0022414 ! reproductive process @@ -12360,6 +1446,7 @@ def: "A cell that has a filiform extrusion of the cell surface." [GOC:tfm] xref: VHOG:0001532 xref: XAO:0000031 is_a: CL:0000003 ! native cell +is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000003 ! native cell intersection_of: has_part GO:0005929 ! cilium relationship: has_part GO:0005929 ! cilium @@ -12386,7 +1473,6 @@ xref: CARO:0000077 xref: FBbt:00000124 xref: FMA:66768 xref: WBbt:0003672 -is_a: BFO:0000004 ! independent continuant is_a: CL:0000548 ! animal cell disjoint_from: CL:0000738 ! leukocyte relationship: part_of UBERON:0000483 ! epithelium @@ -12500,7 +1586,6 @@ relationship: develops_from CL:0000357 ! stratified epithelial stem cell id: CL:0000080 name: circulating cell def: "A cell which moves among different tissues of the body, via blood, lymph, or other medium." [GOC:add] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: part_of UBERON:0000179 ! haemolymphatic fluid @@ -12512,7 +1597,6 @@ name: blood cell def: "A cell found predominately in the blood." [GOC:add, GOC:tfm] xref: FMA:62844 xref: MESH:D001773 -is_a: BFO:0000040 ! material entity is_a: CL:0000988 {is_inferred="true"} ! hematopoietic cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: capable_of GO:0008015 ! blood circulation @@ -12701,19 +1785,19 @@ is_a: CL:0000766 {is_inferred="true"} ! myeloid leukocyte is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000766 ! myeloid leukocyte intersection_of: capable_of GO:0008015 ! blood circulation +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: has_part GO:0030141 ! secretory granule -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain intersection_of: RO:0002104 PR:000001012 ! has plasma membrane part integrin alpha-M intersection_of: RO:0002104 PR:000001332 ! has plasma membrane part carcinoembryonic antigen-related cell adhesion molecule 8 intersection_of: RO:0002104 PR:000001969 ! has plasma membrane part urokinase plasminogen activator surface receptor +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: has_part GO:0030141 ! secretory granule -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001012 ! has plasma membrane part integrin alpha-M relationship: RO:0002104 PR:000001332 ! has plasma membrane part carcinoembryonic antigen-related cell adhesion molecule 8 @@ -12750,11 +1834,11 @@ is_a: CL:0000775 {is_inferred="true"} ! neutrophil relationship: capable_of GO:0002536 ! respiratory burst involved in inflammatory response relationship: capable_of GO:0002690 ! positive regulation of leukocyte chemotaxis relationship: capable_of GO:0032637 ! interleukin-8 production +relationship: CL:4030045 PR:000009978 ! lacks_part lactotransferrin +relationship: CL:4030045 PR:000010543 ! lacks_part myeloperoxidase +relationship: CL:4030045 PR:000010799 ! lacks_part myb proto-oncogene protein relationship: has_part CL:0017500 ! neutrophillic cytoplasm relationship: has_part GO:0070820 ! tertiary granule -relationship: lacks_part PR:000009978 ! lactotransferrin -relationship: lacks_part PR:000010543 ! myeloperoxidase -relationship: lacks_part PR:000010799 ! myb proto-oncogene protein relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001256 ! has plasma membrane part C-X-C chemokine receptor type 1 relationship: RO:0002104 PR:000001257 ! has plasma membrane part C-X-C chemokine receptor type 2 @@ -12787,8 +1871,8 @@ intersection_of: capable_of GO:0002660 ! positive regulation of peripheral toler intersection_of: capable_of GO:0002690 ! positive regulation of leukocyte chemotaxis intersection_of: capable_of GO:0002830 ! positive regulation of type 2 immune response intersection_of: capable_of GO:0030210 ! heparin biosynthetic process +intersection_of: CL:4030046 PR:000001865 ! lacks_plasma_membrane_part interleukin-3 receptor class 2 alpha chain intersection_of: has_part GO:0030141 ! secretory granule -intersection_of: lacks_plasma_membrane_part PR:000001865 ! interleukin-3 receptor class 2 alpha chain intersection_of: RO:0002104 PR:000001255 ! has plasma membrane part C-C chemokine receptor type 3 intersection_of: RO:0002104 PR:000006169 ! has plasma membrane part cell surface glycoprotein CD200 receptor 3 intersection_of: RO:0015015 PR:000002065 ! has high plasma membrane amount mast/stem cell growth factor receptor @@ -12799,9 +1883,9 @@ relationship: capable_of GO:0002660 ! positive regulation of peripheral toleranc relationship: capable_of GO:0002690 ! positive regulation of leukocyte chemotaxis relationship: capable_of GO:0002830 ! positive regulation of type 2 immune response relationship: capable_of GO:0030210 ! heparin biosynthetic process +relationship: CL:4030046 PR:000001865 ! lacks_plasma_membrane_part interleukin-3 receptor class 2 alpha chain relationship: develops_from CL:0000831 ! mast cell progenitor relationship: has_part GO:0030141 ! secretory granule -relationship: lacks_plasma_membrane_part PR:000001865 ! interleukin-3 receptor class 2 alpha chain relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001255 ! has plasma membrane part C-C chemokine receptor type 3 relationship: RO:0002104 PR:000006169 ! has plasma membrane part cell surface glycoprotein CD200 receptor 3 @@ -13162,13 +2246,14 @@ relationship: develops_from CL:0000223 ! endodermal cell [Term] id: CL:0000132 name: corneal endothelial cell -def: "Cell of the single layer of large flattened cells covering the surface of the cornea." [GOC:tfm, MESH:A09.371.060.067.31] +def: "An hexagonal, flattened, mitochondria-rich endothelial cell that forms a monolayer on the posterior surface of the cornea (the corneal endothelium). Corneal endothelial cells are derived from the neural crest and are responsible for keeping the cornea transparent by maintaining the tissue in a semi-dry state through the action of their ionic pumps and tight junction barrier." [GOC:tfm, MESH:A09.371.060.067.31, PMID:21976958, PMID:23284695, PMID:34741068, PMID:36769303] subset: human_reference_atlas xref: CALOHA:TS-0172 xref: FMA:70614 -is_a: CL:0000076 ! squamous epithelial cell +is_a: CL:0000115 ! endothelial cell is_a: CL:0000710 ! neurecto-epithelial cell relationship: develops_from CL:0000008 ! migratory cranial neural crest cell +relationship: part_of UBERON:0001985 ! corneal endothelium relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] @@ -13209,7 +2294,6 @@ name: fibrocyte def: "An inactive fibroblast; cytoplasm is sparse, endoplasmic reticulum is scanty with flattened nucleus. Term used by some histologists; when fibroblasts become relatively inactive in fiber formation. However, this cell has the potential for fibrogenesis in quiescent connective tissue of the adult, as well as during development, other histologists prefer to use the term fibroblast in all circumstances. These cells represent ~0.5% of peripheral blood leukocytes." [GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Fibrocyte, ISBN:0412046911, ISBN:0517223651, PMID:11641248, PMID:15010326, PMID:17607298, PMID:18222966, PMID:8790603, PMID:9551999] comment: Cultured human fibrocytes are MHCI-positive, MHCII-positive, CD1a-negative, CD3-negative, CD4-negative, CD8-negative, CD10-negative, CD11b-positive, CD13-positive, CD14-negative, CD16-negative, CD18-positive, CD19-negative, CD25-negative, CD29-positive, CD32-positive, CD33-negative, CD34-positive, CD38-negative, CD40-positive, CD44-negative, CD45RO-positive, CD49a-positive, CD49b-positive, CD49c-negative, CD49d-negative, CD49e-positive, CD49f-negative, CD56-negative, CD58-positive, CD61-positive, CD64-positive, CD70-negative, CD71-positive, CD80-positive, CD83-negative, CD86-positive, CD103-negative, CD105-positive, CD181-positive, CD182-negative, CD183-positive, CD184-positive, CD185-negative, CD186-negative, CD191-positive, CD192-negative, CD193-positive, CD194-positive, CD195-positive, CD196-negative, CD197-positive, CD199-positive, desmin-negative, F4/80-positive, Gr1-positive, LSP-1-positive, MHCI-positive, MHCII-positive, alpha-SMA-negative, TCRab-negative, TCRgd-negative, and vimentin-positive. Fibrocytes are also capable of secreting angiogenin, bFGF, CCL2, CCL3, CCL4, CCL8, CXCL1, type I collagen, type III collagen, CTGF, fibronectin, GM-CSF, IL-1a, IL-6, IL-8, IL-10, M-CSF, MMP-9, PDGF-A, TGF-alpha, TGF-beta1, TNF-alpha, and VEGF-A. xref: FMA:63879 -is_a: BFO:0000040 ! material entity is_a: CL:0000499 {is_inferred="true"} ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: capable_of GO:0002495 ! antigen processing and presentation of peptide antigen via MHC class II @@ -13269,7 +2353,6 @@ relationship: located_in UBERON:0002418 ! cartilage tissue id: CL:0000140 name: odontocyte def: "Skeletogenic cell that secretes dentine matrix, is derived from odontogenic papilla. Embedded in dentine tissue, and is the transformation of a non-terminally differentiated odontoblast cell." [GO_REF:0000034] -is_a: BFO:0000040 ! material entity is_a: CARO:0000000 ! anatomical entity is_a: CL:0002320 ! connective tissue cell relationship: develops_from CL:0000060 ! odontoblast @@ -13383,7 +2466,6 @@ def: "A cell that specializes in controlled release of one or more substances." subset: human_reference_atlas xref: BTO:0003659 xref: FMA:86916 -is_a: BFO:0000040 ! material entity is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: capable_of GO:0032940 ! secretion by cell @@ -13509,10 +2591,10 @@ subset: human_reference_atlas synonym: "endocrinocyte" EXACT [] xref: FMA:83809 is_a: CL:0000151 ! secretory cell -intersection_of: CL:0000151 ! secretory cell -intersection_of: capable_of GO:0060986 ! endocrine hormone secretion -relationship: capable_of GO:0060986 ! endocrine hormone secretion -relationship: part_of UBERON:0002368 ! endocrine gland +is_a: CL:0000164 {gci_relation="part_of", gci_filler="UBERON:0000945"} ! enteroendocrine cell +is_a: CL:0000164 {gci_filler="UBERON:0000160", gci_relation="part_of"} ! enteroendocrine cell +is_a: CL:0000164 {gci_filler="UBERON:0001264", gci_relation="part_of"} ! enteroendocrine cell +relationship: part_of UBERON:0000949 ! endocrine system relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] @@ -13528,7 +2610,6 @@ is_a: CL:0000163 ! endocrine cell [Term] id: CL:0000165 name: neuroendocrine cell -alt_id: CL:0000381 def: "A neuron that is capable of some hormone secretion in response to neuronal signals." [MESH:D055099] comment: The neurosecretory cell is neither an ordinary neuron nor an endocrine cell, but a combination of both. Its neuronal features resemble those of ordinary neurons concerning both structure and function. The production of a visible secretory material marks the neurosecretory neuron as a gland cell, and the fact that extractable cellular products act in the manner of hormones places it in the realm of endocrine elements. \n\nThe modern definition of neurosecretion has evolved to include the release of any neuronal secretory product from a neuron. {xref="https://www.clinicalkey.com/#!/content/book/3-s2.0-B9780323555968000073", xref="PMID:5342440"} subset: human_reference_atlas @@ -13593,8 +2674,6 @@ xref: EV:0200009 xref: FMA:70586 xref: MA:0002419 xref: ncithesaurus:Beta_Cell -is_a: CL:0000083 ! epithelial cell of pancreas -is_a: CL:0000164 {is_inferred="true"} ! enteroendocrine cell is_a: CL:0000168 {is_inferred="true"} ! insulin secreting cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0000164 ! enteroendocrine cell @@ -13625,7 +2704,6 @@ synonym: "pancreatic alpha cell" EXACT [] xref: BTO:0000990 xref: FMA:70585 xref: MESH:D050416 -is_a: CL:0000083 ! epithelial cell of pancreas is_a: CL:0002067 ! type A enteroendocrine cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0002067 ! type A enteroendocrine cell @@ -13655,7 +2733,6 @@ synonym: "pancreatic delta cell" EXACT [] synonym: "somatostatin-secreting pancreatic cell" EXACT [] xref: BTO:0000803 xref: FMA:70587 -is_a: CL:0000083 ! epithelial cell of pancreas is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0000502 ! type D enteroendocrine cell @@ -13667,7 +2744,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: CL:0000174 name: steroid hormone secreting cell -is_a: CL:0000163 ! endocrine cell +is_a: CL:0000151 ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0035929 ! steroid hormone secretion relationship: capable_of GO:0035929 ! steroid hormone secretion @@ -13753,7 +2830,6 @@ subset: human_reference_atlas xref: BTO:0000575 xref: CALOHA:TS-0454 xref: FMA:14515 -is_a: BFO:0000040 ! material entity is_a: CARO:0000000 ! anatomical entity is_a: CL:0000066 ! epithelial cell is_a: CL:0000417 ! endopolyploid cell @@ -13825,7 +2901,6 @@ synonym: "skeletal muscle cell" EXACT [] xref: BTO:0004392 xref: CALOHA:TS-2158 xref: FMA:9727 -is_a: BFO:0000004 ! independent continuant is_a: CL:0002371 ! somatic cell intersection_of: CL:0002371 ! somatic cell intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue @@ -13900,7 +2975,6 @@ name: sensory receptor cell def: "A cell that is capable of detection of a stimulus involved in sensory perception." [] synonym: "receptor cell" EXACT [] xref: MESH:D011984 -is_a: BFO:0000040 ! material entity is_a: CL:0000003 ! native cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception @@ -13930,7 +3004,9 @@ relationship: capable_of GO:0050974 ! detection of mechanical stimulus involved [Term] id: CL:0000200 name: touch receptor cell +is_a: CL:0000006 ! neuronal receptor cell is_a: CL:0000199 ! mechanoreceptor cell +is_a: CL:4023168 ! somatosensory neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch relationship: capable_of GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch @@ -14103,7 +3179,6 @@ relationship: develops_from CL:0002377 ! immature Schwann cell id: CL:0000219 name: motile cell def: "A cell that moves by its own activities." [FB:ma] -is_a: BFO:0000040 ! material entity is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: capable_of GO:0048870 ! cell motility @@ -14124,7 +3199,6 @@ name: ectodermal cell def: "A cell of the outer of the three germ layers of the embryo." [MESH:D004475] synonym: "ectoderm cell" EXACT [] xref: FMA:72549 -is_a: BFO:0000004 ! independent continuant is_a: CL:0002321 ! embryonic cell (metazoa) relationship: part_of UBERON:0000924 ! ectoderm @@ -14135,7 +3209,6 @@ def: "A cell of the middle germ layer of the embryo." [MESH:D008648] synonym: "mesoblast" EXACT [] synonym: "mesoderm cell" EXACT [] xref: FMA:72554 -is_a: BFO:0000004 ! independent continuant is_a: CL:0002321 ! embryonic cell (metazoa) relationship: part_of UBERON:0000926 ! mesoderm @@ -14145,7 +3218,6 @@ name: endodermal cell def: "A cell of the inner of the three germ layers of the embryo." [MESH:D004707] synonym: "endoderm cell" EXACT [] xref: FMA:72555 -is_a: BFO:0000004 ! independent continuant is_a: CL:0002321 ! embryonic cell (metazoa) relationship: part_of UBERON:0000925 ! endoderm @@ -14240,12 +3312,12 @@ intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: bearer_of PATO:0002039 ! biconcave intersection_of: capable_of GO:0008015 ! blood circulation intersection_of: capable_of GO:0015671 ! oxygen transport -intersection_of: lacks_part GO:0005840 ! ribosome -intersection_of: lacks_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 +intersection_of: CL:4030045 GO:0005840 ! lacks_part ribosome +intersection_of: CL:4030046 PR:000001945 ! lacks_plasma_membrane_part transferrin receptor protein 1 relationship: bearer_of PATO:0002039 ! biconcave +relationship: CL:4030045 GO:0005840 ! lacks_part ribosome +relationship: CL:4030046 PR:000001945 ! lacks_plasma_membrane_part transferrin receptor protein 1 relationship: develops_from CL:0000558 ! reticulocyte -relationship: lacks_part GO:0005840 ! ribosome -relationship: lacks_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] @@ -14877,7 +3949,6 @@ synonym: "malpighian cell" EXACT [] xref: BTO:0000667 xref: CALOHA:TS-0500 xref: FMA:62879 -is_a: BFO:0000040 ! material entity is_a: CL:0000237 {is_inferred="true"} ! keratinizing barrier epithelial cell is_a: CL:0000362 {is_inferred="true"} ! epidermal cell intersection_of: CL:0000237 ! keratinizing barrier epithelial cell @@ -15005,7 +4076,6 @@ is_a: CL:0000499 ! stromal cell [Term] id: CL:0000329 name: oxygen accumulating cell -is_a: BFO:0000040 ! material entity is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: capable_of GO:0015671 ! oxygen transport @@ -15116,7 +4186,6 @@ id: CL:0000343 name: visual pigment cell (sensu Vertebrata) def: "A pigment cell that is capable of detecting light stimulus that is involved in visual perception." [GOC:tfm] xref: FMA:63846 -is_a: BFO:0000040 ! material entity is_a: CL:0000149 ! visual pigment cell is_a: CL:0000342 {is_inferred="true"} ! pigment cell (sensu Vertebrata) intersection_of: CL:0000342 ! pigment cell (sensu Vertebrata) @@ -15175,7 +4244,6 @@ relationship: part_of UBERON:0001776 ! optic choroid [Term] id: CL:0000349 name: extraembryonic cell -is_a: BFO:0000004 ! independent continuant is_a: CL:0000548 ! animal cell is_a: CL:0002371 ! somatic cell intersection_of: CL:0000548 ! animal cell @@ -15268,7 +4336,6 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000360 name: morula cell def: "A cell of the early embryo at the developmental stage in which the blastomeres, resulting from repeated mitotic divisions of the fertilized ovum (zygote), form a compact cell mass." [MESH:D009028] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000007 ! early embryonic cell (metazoa) relationship: part_of UBERON:0000085 ! morula @@ -15276,7 +4343,6 @@ relationship: part_of UBERON:0000085 ! morula id: CL:0000361 name: gastrula cell def: "A cell of the embryo in the early stage following the blastula, characterized by morphogenetic cell movements, cell differentiation, and the formation of the three germ layers." [MESH:D005775] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000007 ! early embryonic cell (metazoa) relationship: part_of UBERON:0004734 ! gastrula @@ -15818,13 +4884,12 @@ xref: BTO:0002482 xref: FMA:83100 is_a: CL:0000438 ! luteinizing hormone secreting cell is_a: CL:0000639 ! basophil cell of pars distalis of adenohypophysis -is_a: CL:0011111 ! gonadotropin releasing neuron [Term] id: CL:0000438 name: luteinizing hormone secreting cell def: "A peptide hormone secreting cell pituitary that produces luteinizing hormone." [GOC:tfm] -is_a: CL:0000163 ! endocrine cell +is_a: CL:0000151 ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0032275 ! luteinizing hormone secretion relationship: capable_of GO:0032275 ! luteinizing hormone secretion @@ -15957,21 +5022,21 @@ intersection_of: capable_of GO:0001816 ! cytokine production intersection_of: capable_of GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II intersection_of: capable_of GO:0019882 ! antigen processing and presentation intersection_of: capable_of GO:0045580 ! regulation of T cell differentiation +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: has_part GO:0042613 ! MHC class II protein complex -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 disjoint_from: CL:0000542 ! lymphocyte relationship: capable_of GO:0001816 ! cytokine production relationship: capable_of GO:0045580 ! regulation of T cell differentiation +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: has_part GO:0042613 ! MHC class II protein complex -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] @@ -16104,7 +5169,6 @@ synonym: "adrenocorticotrophic hormone secreting cell" EXACT [] synonym: "corticotrophin hormone secreting cell" EXACT [] synonym: "corticotropin hormone secreting cell" EXACT [] synonym: "corticotropin secreting cell" EXACT [GO:0051458] -is_a: CL:0000163 ! endocrine cell is_a: CL:0000167 ! peptide hormone secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0051458 ! corticotropin secretion @@ -16215,7 +5279,7 @@ id: CL:0000482 name: juvenile hormone secreting cell def: "An endocrine cell that secretes juvenile hormone." [GO:tfm] xref: FBbt:00058020 -is_a: CL:0000163 ! endocrine cell +is_a: CL:0000151 ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0045443 ! juvenile hormone secretion relationship: capable_of GO:0045443 ! juvenile hormone secretion @@ -16466,12 +5530,13 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: CL:0000510 name: paneth cell -def: "An epithelial cell found in the basal part of the intestinal glands (crypts of Lieberkuhn) including the appendix. Paneth cells synthesize and secrete lysozyme and cryptdins. Numerous in the deeper parts of the intestinal crypts, particularly in the duodenum, rich in zinc, contain large acidophilic granules, with irregular apical microvilli and prominent membrane-bound vacuoles containing matrix." [GOC:tfm, ISBN:0517223651, MESH:D019879] +def: "An epithelial cell found in the basal part of the intestinal glands (crypts of Lieberkuhn) including the appendix. Paneth cells synthesize and secrete lysozyme and cryptdins. Numerous in the deeper parts of the intestinal crypts, particularly in the duodenum, rich in zinc, contain large acidophilic granules, with irregular apical microvilli and prominent membrane-bound vacuoles containing matrix." [GOC:tfm, ISBN:0517223651, MESH:D019879, PMID:29184701, PMID:32308658] xref: BTO:0000993 xref: FMA:62897 is_a: CL:0000150 {is_inferred="true"} ! glandular epithelial cell is_a: CL:0000323 ! lysozyme secreting cell is_a: CL:0002563 ! intestinal epithelial cell +relationship: part_of UBERON:0001983 ! crypt of Lieberkuhn [Term] id: CL:0000511 @@ -16720,7 +5785,6 @@ xref: FBbt:00005106 xref: FMA:54527 xref: VHOG:0001483 xref: WBbt:0003679 -is_a: BFO:0000040 ! material entity is_a: CL:0000393 ! electrically responsive cell is_a: CL:0000404 ! electrically signaling cell is_a: CL:0002319 ! neural cell @@ -16797,12 +5861,12 @@ xref: FMA:84382 is_a: CL:0000492 {is_inferred="true"} ! CD4-positive helper T cell intersection_of: CL:0000492 ! CD4-positive helper T cell intersection_of: capable_of GO:0032609 ! type II interferon production +intersection_of: CL:4030046 PR:000001202 ! lacks_plasma_membrane_part C-C chemokine receptor type 6 intersection_of: has_part PR:000001835 ! T-box transcription factor TBX21 -intersection_of: lacks_plasma_membrane_part PR:000001202 ! C-C chemokine receptor type 6 intersection_of: RO:0002104 PR:000001207 ! has plasma membrane part C-X-C chemokine receptor type 3 relationship: capable_of GO:0032609 ! type II interferon production +relationship: CL:4030046 PR:000001202 ! lacks_plasma_membrane_part C-C chemokine receptor type 6 relationship: has_part PR:000001835 ! T-box transcription factor TBX21 -relationship: lacks_plasma_membrane_part PR:000001202 ! C-C chemokine receptor type 6 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001207 ! has plasma membrane part C-X-C chemokine receptor type 3 @@ -16827,9 +5891,9 @@ is_a: CL:0000492 {is_inferred="true"} ! CD4-positive helper T cell is_a: CL:0001051 ! CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell intersection_of: CL:0000492 ! CD4-positive helper T cell intersection_of: capable_of GO:0032633 ! interleukin-4 production +intersection_of: CL:4030046 PR:000001202 ! lacks_plasma_membrane_part C-C chemokine receptor type 6 +intersection_of: CL:4030046 PR:000001207 ! lacks_plasma_membrane_part C-X-C chemokine receptor type 3 intersection_of: has_part PR:000001941 ! trans-acting T-cell-specific transcription factor GATA-3 -intersection_of: lacks_plasma_membrane_part PR:000001202 ! C-C chemokine receptor type 6 -intersection_of: lacks_plasma_membrane_part PR:000001207 ! C-X-C chemokine receptor type 3 relationship: capable_of GO:0032633 ! interleukin-4 production relationship: has_part PR:000001941 ! trans-acting T-cell-specific transcription factor GATA-3 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens @@ -16844,38 +5908,39 @@ xref: FMA:83518 is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell is_a: CL:0002242 ! nucleate cell +is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: bearer_of PATO:0002505 ! nucleated +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_part CL:0017503 ! basophilic cytoplasm intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0005730 ! nucleolus -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -intersection_of: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -intersection_of: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000038 ! erythroid progenitor cell relationship: has_part CL:0017503 ! basophilic cytoplasm relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0005730 ! nucleolus -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -relationship: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -relationship: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -relationship: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 [Term] @@ -16980,33 +6045,33 @@ is_a: CL:0000839 {is_inferred="true"} ! myeloid lineage restricted progenitor ce intersection_of: CL:0000839 ! myeloid lineage restricted progenitor cell intersection_of: capable_of GO:0007113 ! endomitotic cell cycle intersection_of: capable_of GO:0030219 ! megakaryocyte differentiation -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -intersection_of: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -intersection_of: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -intersection_of: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: capable_of GO:0007113 ! endomitotic cell cycle relationship: capable_of GO:0030219 ! megakaryocyte differentiation +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: develops_from CL:0000050 ! megakaryocyte-erythroid progenitor cell -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -relationship: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -relationship: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -relationship: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -relationship: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] @@ -17023,7 +6088,7 @@ is_a: CL:0000117 ! CNS neuron (sensu Vertebrata) [Term] id: CL:0000556 name: megakaryocyte -def: "A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm." [http://en.wikipedia.org/wiki/Megakaryocyte, ISBN:0721601464, MESH:D008533] +def: "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release." [http://en.wikipedia.org/wiki/Megakaryocyte, ISBN:0721601464, MESH:D008533, PMID:31043076] comment: Megakaryocytes are reportedly CD181-positive and CD182-positive. subset: human_reference_atlas synonym: "megacaryocyte" EXACT [] @@ -17033,10 +6098,7 @@ xref: BTO:0000843 xref: CALOHA:TS-0611 xref: FMA:83555 is_a: CL:0000763 {is_inferred="true"} ! myeloid cell -is_a: CL:1001610 ! bone marrow hematopoietic cell -intersection_of: CL:0000763 ! myeloid cell -intersection_of: bearer_of PATO:0001393 ! euploid -intersection_of: part_of UBERON:0002371 ! bone marrow +is_a: CL:4033018 {gci_relation="part_of", gci_filler="UBERON:0000114"} ! lung megakaryocyte disjoint_from: CL:0000764 ! erythroid lineage cell relationship: bearer_of PATO:0001393 ! euploid relationship: develops_from CL:0000553 ! megakaryocyte progenitor cell @@ -17064,18 +6126,18 @@ is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: capable_of GO:0030225 ! macrophage differentiation intersection_of: capable_of GO:0030851 ! granulocyte differentiation +intersection_of: CL:4030045 PR:000007857 ! lacks_part erythroid transcription factor +intersection_of: CL:4030045 PR:000007858 ! lacks_part endothelial transcription factor GATA-2 intersection_of: has_part PR:000001944 ! transcription factor PU.1 intersection_of: has_part PR:000005307 ! CCAAT/enhancer-binding protein alpha -intersection_of: lacks_part PR:000007857 ! erythroid transcription factor -intersection_of: lacks_part PR:000007858 ! endothelial transcription factor GATA-2 intersection_of: part_of UBERON:0002371 ! bone marrow intersection_of: RO:0002104 PR:000001865 ! has plasma membrane part interleukin-3 receptor class 2 alpha chain relationship: capable_of GO:0030225 ! macrophage differentiation relationship: capable_of GO:0030851 ! granulocyte differentiation +relationship: CL:4030045 PR:000007857 ! lacks_part erythroid transcription factor +relationship: CL:4030045 PR:000007858 ! lacks_part endothelial transcription factor GATA-2 relationship: has_part PR:000001944 ! transcription factor PU.1 relationship: has_part PR:000005307 ! CCAAT/enhancer-binding protein alpha -relationship: lacks_part PR:000007857 ! erythroid transcription factor -relationship: lacks_part PR:000007858 ! endothelial transcription factor GATA-2 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001865 ! has plasma membrane part interleukin-3 receptor class 2 alpha chain @@ -17091,31 +6153,31 @@ is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: capable_of GO:0071971 ! extracellular exosome assembly -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -intersection_of: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -intersection_of: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 relationship: capable_of GO:0071971 ! extracellular exosome assembly +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000552 ! orthochromatic erythroblast -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -relationship: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -relationship: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -relationship: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 [Term] @@ -17151,26 +6213,24 @@ synonym: "rod neutrophil" EXACT [] synonym: "stab cell" BROAD [] is_a: CL:0000096 {is_inferred="true"} ! mature neutrophil intersection_of: CL:0000096 ! mature neutrophil +intersection_of: CL:4030045 PR:000009978 ! lacks_part lactotransferrin +intersection_of: CL:4030045 PR:000010799 ! lacks_part myb proto-oncogene protein +intersection_of: CL:4030046 PR:000009129 ! lacks_plasma_membrane_part integrin alpha-4 +intersection_of: CL:4030046 PR:000010543 ! lacks_plasma_membrane_part myeloperoxidase intersection_of: has_part CL:0017506 ! banded nucleus intersection_of: has_part PR:000001944 ! transcription factor PU.1 intersection_of: has_part PR:000005307 ! CCAAT/enhancer-binding protein alpha intersection_of: has_part PR:000007597 ! protein c-Fos -intersection_of: lacks_part PR:000009978 ! lactotransferrin -intersection_of: lacks_part PR:000010799 ! myb proto-oncogene protein -intersection_of: lacks_plasma_membrane_part PR:000009129 ! integrin alpha-4 -intersection_of: lacks_plasma_membrane_part PR:000010543 ! myeloperoxidase intersection_of: RO:0002104 PR:000001012 ! has plasma membrane part integrin alpha-M intersection_of: RO:0002104 PR:000001337 ! has plasma membrane part complement receptor type 1 intersection_of: RO:0002104 PR:000001580 ! has plasma membrane part fMet-Leu-Phe receptor +relationship: CL:4030046 PR:000009129 ! lacks_plasma_membrane_part integrin alpha-4 +relationship: CL:4030046 PR:000010543 ! lacks_plasma_membrane_part myeloperoxidase relationship: develops_from CL:0000582 ! neutrophilic metamyelocyte relationship: has_part CL:0017506 ! banded nucleus relationship: has_part PR:000001944 ! transcription factor PU.1 relationship: has_part PR:000005307 ! CCAAT/enhancer-binding protein alpha relationship: has_part PR:000007597 ! protein c-Fos -relationship: lacks_part PR:000009978 ! lactotransferrin -relationship: lacks_part PR:000010799 ! myb proto-oncogene protein -relationship: lacks_plasma_membrane_part PR:000009129 ! integrin alpha-4 -relationship: lacks_plasma_membrane_part PR:000010543 ! myeloperoxidase relationship: RO:0002104 PR:000001337 ! has plasma membrane part complement receptor type 1 relationship: RO:0002104 PR:000001580 ! has plasma membrane part fMet-Leu-Phe receptor @@ -17222,19 +6282,19 @@ is_a: CL:0000834 ! neutrophil progenitor cell is_a: CL:0000836 {is_inferred="true"} ! promyelocyte intersection_of: CL:0000836 ! promyelocyte intersection_of: capable_of GO:0030223 ! neutrophil differentiation +intersection_of: CL:4030045 PR:000009978 ! lacks_part lactotransferrin intersection_of: has_part PR:000001944 ! transcription factor PU.1 intersection_of: has_part PR:000005307 ! CCAAT/enhancer-binding protein alpha intersection_of: has_part PR:000007857 ! erythroid transcription factor intersection_of: has_part PR:000010543 ! myeloperoxidase intersection_of: has_part PR:000014362 ! runt-related transcription factor 1 -intersection_of: lacks_part PR:000009978 ! lactotransferrin +relationship: CL:4030045 PR:000009978 ! lacks_part lactotransferrin relationship: develops_from CL:0000042 ! neutrophilic myeloblast relationship: has_part PR:000001944 ! transcription factor PU.1 relationship: has_part PR:000005307 ! CCAAT/enhancer-binding protein alpha relationship: has_part PR:000007857 ! erythroid transcription factor relationship: has_part PR:000010543 ! myeloperoxidase relationship: has_part PR:000014362 ! runt-related transcription factor 1 -relationship: lacks_part PR:000009978 ! lactotransferrin [Term] id: CL:0000565 @@ -17423,6 +6483,8 @@ is_a: CL:0000776 {is_inferred="true"} ! immature neutrophil is_a: CL:0002087 ! nongranular leukocyte is_a: CL:0002193 ! myelocyte intersection_of: CL:0000776 ! immature neutrophil +intersection_of: CL:4030045 GO:0070820 ! lacks_part tertiary granule +intersection_of: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III intersection_of: has_part CL:0017502 ! acidophilic cytoplasm intersection_of: has_part GO:0042582 ! azurophil granule intersection_of: has_part PR:000001944 ! transcription factor PU.1 @@ -17431,13 +6493,13 @@ intersection_of: has_part PR:000005310 ! CCAAT/enhancer-binding protein epsilon intersection_of: has_part PR:000009725 ! neutrophil gelatinase-associated lipocalin intersection_of: has_part PR:000009978 ! lactotransferrin intersection_of: has_part PR:000010543 ! myeloperoxidase -intersection_of: lacks_part GO:0070820 ! tertiary granule -intersection_of: lacks_plasma_membrane_part PR:000001483 ! low affinity immunoglobulin gamma Fc region receptor III intersection_of: RO:0002104 PR:000001012 ! has plasma membrane part integrin alpha-M intersection_of: RO:0002104 PR:000001456 ! has plasma membrane part alpha-(1,3)-fucosyltransferase 4 intersection_of: RO:0002104 PR:000001892 ! has plasma membrane part CD33 molecule intersection_of: RO:0002104 PR:000001932 ! has plasma membrane part signal transducer CD24 intersection_of: RO:0002104 PR:000002031 ! has plasma membrane part aminopeptidase N +relationship: CL:4030045 GO:0070820 ! lacks_part tertiary granule +relationship: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III relationship: has_part CL:0017502 ! acidophilic cytoplasm relationship: has_part GO:0042582 ! azurophil granule relationship: has_part PR:000001944 ! transcription factor PU.1 @@ -17446,8 +6508,6 @@ relationship: has_part PR:000005310 ! CCAAT/enhancer-binding protein epsilon relationship: has_part PR:000009725 ! neutrophil gelatinase-associated lipocalin relationship: has_part PR:000009978 ! lactotransferrin relationship: has_part PR:000010543 ! myeloperoxidase -relationship: lacks_part GO:0070820 ! tertiary granule -relationship: lacks_plasma_membrane_part PR:000001483 ! low affinity immunoglobulin gamma Fc region receptor III relationship: RO:0002104 PR:000001456 ! has plasma membrane part alpha-(1,3)-fucosyltransferase 4 relationship: RO:0002104 PR:000001892 ! has plasma membrane part CD33 molecule relationship: RO:0002104 PR:000001932 ! has plasma membrane part signal transducer CD24 @@ -17465,7 +6525,7 @@ is_a: CL:0000864 {is_inferred="true"} ! tissue-resident macrophage is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000864 ! tissue-resident macrophage intersection_of: capable_of GO:0042742 ! defense response to bacterium -intersection_of: lacks_plasma_membrane_part GO:0042613 ! MHC class II protein complex +intersection_of: CL:4030046 GO:0042613 ! lacks_plasma_membrane_part MHC class II protein complex intersection_of: located_in UBERON:0001179 ! peritoneal cavity intersection_of: RO:0002104 PR:000001807 ! has plasma membrane part C-type lectin domain family 7 member A intersection_of: RO:0002104 PR:000002064 ! has plasma membrane part macrosialin @@ -17474,7 +6534,7 @@ intersection_of: RO:0015015 PR:000001012 ! has high plasma membrane amount integ intersection_of: RO:0015015 PR:000001813 ! has high plasma membrane amount adhesion G protein-coupled receptor E1 intersection_of: RO:0015015 PR:000002062 ! has high plasma membrane amount macrophage colony-stimulating factor 1 receptor relationship: capable_of GO:0042742 ! defense response to bacterium -relationship: lacks_plasma_membrane_part GO:0042613 ! MHC class II protein complex +relationship: CL:4030046 GO:0042613 ! lacks_plasma_membrane_part MHC class II protein complex relationship: located_in UBERON:0001179 ! peritoneal cavity relationship: RO:0002104 PR:000001807 ! has plasma membrane part C-type lectin domain family 7 member A relationship: RO:0002104 PR:000002064 ! has plasma membrane part macrosialin @@ -17493,6 +6553,7 @@ xref: FMA:84197 is_a: CL:0000776 {is_inferred="true"} ! immature neutrophil is_a: CL:0002192 ! metamyelocyte intersection_of: CL:0000776 ! immature neutrophil +intersection_of: CL:4030046 PR:000001580 ! lacks_plasma_membrane_part fMet-Leu-Phe receptor intersection_of: has_part CL:0017502 ! acidophilic cytoplasm intersection_of: has_part CL:0017507 ! reniform nucleus intersection_of: has_part GO:0000792 ! heterochromatin @@ -17504,13 +6565,13 @@ intersection_of: has_part PR:000005310 ! CCAAT/enhancer-binding protein epsilon intersection_of: has_part PR:000009725 ! neutrophil gelatinase-associated lipocalin intersection_of: has_part PR:000009978 ! lactotransferrin intersection_of: has_part PR:000010543 ! myeloperoxidase -intersection_of: lacks_plasma_membrane_part PR:000001580 ! fMet-Leu-Phe receptor intersection_of: RO:0002104 PR:000001012 ! has plasma membrane part integrin alpha-M intersection_of: RO:0002104 PR:000001456 ! has plasma membrane part alpha-(1,3)-fucosyltransferase 4 intersection_of: RO:0002104 PR:000001483 ! has plasma membrane part low affinity immunoglobulin gamma Fc region receptor III intersection_of: RO:0002104 PR:000001892 ! has plasma membrane part CD33 molecule intersection_of: RO:0002104 PR:000001932 ! has plasma membrane part signal transducer CD24 intersection_of: RO:0002104 PR:000002031 ! has plasma membrane part aminopeptidase N +relationship: CL:4030046 PR:000001580 ! lacks_plasma_membrane_part fMet-Leu-Phe receptor relationship: develops_from CL:0000580 ! neutrophilic myelocyte relationship: has_part CL:0017502 ! acidophilic cytoplasm relationship: has_part CL:0017507 ! reniform nucleus @@ -17523,7 +6584,6 @@ relationship: has_part PR:000005310 ! CCAAT/enhancer-binding protein epsilon relationship: has_part PR:000009725 ! neutrophil gelatinase-associated lipocalin relationship: has_part PR:000009978 ! lactotransferrin relationship: has_part PR:000010543 ! myeloperoxidase -relationship: lacks_plasma_membrane_part PR:000001580 ! fMet-Leu-Phe receptor relationship: RO:0002104 PR:000001456 ! has plasma membrane part alpha-(1,3)-fucosyltransferase 4 relationship: RO:0002104 PR:000001483 ! has plasma membrane part low affinity immunoglobulin gamma Fc region receptor III relationship: RO:0002104 PR:000001892 ! has plasma membrane part CD33 molecule @@ -17547,7 +6607,7 @@ is_a: CL:1001603 ! lung macrophage is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000864 ! tissue-resident macrophage intersection_of: capable_of GO:0019882 ! antigen processing and presentation -intersection_of: lacks_plasma_membrane_part PR:000001206 ! CX3C chemokine receptor 1 +intersection_of: CL:4030046 PR:000001206 ! lacks_plasma_membrane_part CX3C chemokine receptor 1 intersection_of: located_in UBERON:0002299 ! alveolus of lung intersection_of: RO:0002104 PR:000001013 ! has plasma membrane part integrin alpha-X intersection_of: RO:0002104 PR:000001807 ! has plasma membrane part C-type lectin domain family 7 member A @@ -17556,7 +6616,7 @@ intersection_of: RO:0002104 PR:000001931 ! has plasma membrane part sialoadhesin intersection_of: RO:0002104 PR:000002064 ! has plasma membrane part macrosialin intersection_of: RO:0002104 PR:000002972 ! has plasma membrane part macrophage mannose receptor 1 intersection_of: RO:0015016 PR:000001012 ! has low plasma membrane amount integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001206 ! CX3C chemokine receptor 1 +relationship: CL:4030046 PR:000001206 ! lacks_plasma_membrane_part CX3C chemokine receptor 1 relationship: located_in UBERON:0002299 ! alveolus of lung relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001013 ! has plasma membrane part integrin alpha-X @@ -17820,43 +6880,43 @@ is_a: CL:0002191 {is_inferred="true"} ! granulocytopoietic cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0002191 ! granulocytopoietic cell intersection_of: capable_of GO:0030222 ! eosinophil differentiation +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: has_part PR:000001944 ! transcription factor PU.1 intersection_of: has_part PR:000005307 ! CCAAT/enhancer-binding protein alpha intersection_of: has_part PR:000007857 ! erythroid transcription factor -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -intersection_of: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -intersection_of: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -intersection_of: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule intersection_of: RO:0002104 PR:000001408 ! has plasma membrane part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 intersection_of: RO:0002104 PR:000001865 ! has plasma membrane part interleukin-3 receptor class 2 alpha chain intersection_of: RO:0002104 PR:000001867 ! has plasma membrane part interleukin-5 receptor subunit alpha intersection_of: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor relationship: capable_of GO:0030222 ! eosinophil differentiation +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: develops_from CL:0000557 ! granulocyte monocyte progenitor cell relationship: has_part PR:000001944 ! transcription factor PU.1 relationship: has_part PR:000005307 ! CCAAT/enhancer-binding protein alpha relationship: has_part PR:000007857 ! erythroid transcription factor -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -relationship: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -relationship: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -relationship: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -relationship: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) relationship: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule relationship: RO:0002104 PR:000001408 ! has plasma membrane part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 relationship: RO:0002104 PR:000001865 ! has plasma membrane part interleukin-3 receptor class 2 alpha chain @@ -17873,17 +6933,17 @@ is_a: CL:0000772 {is_inferred="true"} ! immature eosinophil is_a: CL:0002087 ! nongranular leukocyte is_a: CL:0002193 ! myelocyte intersection_of: CL:0000772 ! immature eosinophil +intersection_of: CL:4030045 GO:0070820 ! lacks_part tertiary granule +intersection_of: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III intersection_of: has_part GO:0042582 ! azurophil granule -intersection_of: lacks_part GO:0070820 ! tertiary granule -intersection_of: lacks_plasma_membrane_part PR:000001483 ! low affinity immunoglobulin gamma Fc region receptor III intersection_of: RO:0002104 PR:000001012 ! has plasma membrane part integrin alpha-M intersection_of: RO:0002104 PR:000001456 ! has plasma membrane part alpha-(1,3)-fucosyltransferase 4 intersection_of: RO:0002104 PR:000001892 ! has plasma membrane part CD33 molecule intersection_of: RO:0002104 PR:000001932 ! has plasma membrane part signal transducer CD24 intersection_of: RO:0002104 PR:000002031 ! has plasma membrane part aminopeptidase N +relationship: CL:4030045 GO:0070820 ! lacks_part tertiary granule +relationship: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III relationship: has_part GO:0042582 ! azurophil granule -relationship: lacks_part GO:0070820 ! tertiary granule -relationship: lacks_plasma_membrane_part PR:000001483 ! low affinity immunoglobulin gamma Fc region receptor III relationship: RO:0002104 PR:000001456 ! has plasma membrane part alpha-(1,3)-fucosyltransferase 4 relationship: RO:0002104 PR:000001892 ! has plasma membrane part CD33 molecule relationship: RO:0002104 PR:000001932 ! has plasma membrane part signal transducer CD24 @@ -17904,42 +6964,42 @@ is_a: CL:0002191 {is_inferred="true"} ! granulocytopoietic cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0002191 ! granulocytopoietic cell intersection_of: capable_of GO:0030221 ! basophil differentiation +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +intersection_of: CL:4030046 PR:000002065 ! lacks_plasma_membrane_part mast/stem cell growth factor receptor +intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: has_part PR:000005307 ! CCAAT/enhancer-binding protein alpha intersection_of: has_part PR:000007857 ! erythroid transcription factor intersection_of: has_part PR:000007858 ! endothelial transcription factor GATA-2 -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -intersection_of: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -intersection_of: lacks_plasma_membrane_part PR:000002065 ! mast/stem cell growth factor receptor -intersection_of: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -intersection_of: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) intersection_of: RO:0015015 PR:000007431 ! has high plasma membrane amount high affinity immunoglobulin epsilon receptor subunit alpha intersection_of: RO:0015016 PR:000016401 ! has low plasma membrane amount transmembrane emp24 domain-containing protein 1 relationship: capable_of GO:0030221 ! basophil differentiation +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +relationship: CL:4030046 PR:000002065 ! lacks_plasma_membrane_part mast/stem cell growth factor receptor +relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: develops_from CL:0002028 ! basophil mast progenitor cell relationship: has_part PR:000005307 ! CCAAT/enhancer-binding protein alpha relationship: has_part PR:000007857 ! erythroid transcription factor relationship: has_part PR:000007858 ! endothelial transcription factor GATA-2 -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -relationship: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -relationship: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -relationship: lacks_plasma_membrane_part PR:000002065 ! mast/stem cell growth factor receptor -relationship: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -relationship: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) relationship: RO:0015015 PR:000007431 ! has high plasma membrane amount high affinity immunoglobulin epsilon receptor subunit alpha relationship: RO:0015016 PR:000016401 ! has low plasma membrane amount transmembrane emp24 domain-containing protein 1 @@ -17952,19 +7012,19 @@ xref: FMA:83543 is_a: CL:0000768 {is_inferred="true"} ! immature basophil is_a: CL:0002087 ! nongranular leukocyte intersection_of: CL:0000768 ! immature basophil +intersection_of: CL:4030045 GO:0005730 ! lacks_part nucleolus +intersection_of: CL:4030045 GO:0070820 ! lacks_part tertiary granule +intersection_of: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III intersection_of: has_part GO:0042582 ! azurophil granule -intersection_of: lacks_part GO:0005730 ! nucleolus -intersection_of: lacks_part GO:0070820 ! tertiary granule -intersection_of: lacks_plasma_membrane_part PR:000001483 ! low affinity immunoglobulin gamma Fc region receptor III intersection_of: RO:0002104 PR:000001012 ! has plasma membrane part integrin alpha-M intersection_of: RO:0002104 PR:000001456 ! has plasma membrane part alpha-(1,3)-fucosyltransferase 4 intersection_of: RO:0002104 PR:000001892 ! has plasma membrane part CD33 molecule intersection_of: RO:0002104 PR:000001932 ! has plasma membrane part signal transducer CD24 intersection_of: RO:0002104 PR:000002031 ! has plasma membrane part aminopeptidase N +relationship: CL:4030045 GO:0005730 ! lacks_part nucleolus +relationship: CL:4030045 GO:0070820 ! lacks_part tertiary granule +relationship: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III relationship: has_part GO:0042582 ! azurophil granule -relationship: lacks_part GO:0005730 ! nucleolus -relationship: lacks_part GO:0070820 ! tertiary granule -relationship: lacks_plasma_membrane_part PR:000001483 ! low affinity immunoglobulin gamma Fc region receptor III relationship: RO:0002104 PR:000001456 ! has plasma membrane part alpha-(1,3)-fucosyltransferase 4 relationship: RO:0002104 PR:000001892 ! has plasma membrane part CD33 molecule relationship: RO:0002104 PR:000001932 ! has plasma membrane part signal transducer CD24 @@ -18054,15 +7114,15 @@ is_a: CL:0001067 ! group 1 innate lymphoid cell intersection_of: CL:0001067 ! group 1 innate lymphoid cell intersection_of: capable_of GO:0002228 ! natural killer cell mediated immunity intersection_of: capable_of GO:0050776 ! regulation of immune response -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -intersection_of: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: capable_of GO:0002228 ! natural killer cell mediated immunity relationship: capable_of GO:0050776 ! regulation of immune response +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: develops_from CL:0000825 ! pro-NK cell -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] @@ -18075,10 +7135,10 @@ synonym: "CD4-positive, alpha-beta T-cell" EXACT [] synonym: "CD4-positive, alpha-beta T-lymphocyte" EXACT [] is_a: CL:0000791 {is_inferred="true"} ! mature alpha-beta T cell intersection_of: CL:0000791 ! mature alpha-beta T cell -intersection_of: lacks_plasma_membrane_part PR:000025402 ! T cell receptor co-receptor CD8 +intersection_of: CL:4030046 PR:000025402 ! lacks_plasma_membrane_part T cell receptor co-receptor CD8 intersection_of: RO:0002104 PR:000001004 ! has plasma membrane part CD4 molecule disjoint_from: CL:0000625 ! CD8-positive, alpha-beta T cell -relationship: lacks_plasma_membrane_part PR:000025402 ! T cell receptor co-receptor CD8 +relationship: CL:4030046 PR:000025402 ! lacks_plasma_membrane_part T cell receptor co-receptor CD8 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001004 ! has plasma membrane part CD4 molecule @@ -18092,9 +7152,9 @@ synonym: "CD8-positive, alpha-beta T-cell" EXACT [] synonym: "CD8-positive, alpha-beta T-lymphocyte" EXACT [] is_a: CL:0000791 {is_inferred="true"} ! mature alpha-beta T cell intersection_of: CL:0000791 ! mature alpha-beta T cell -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: RO:0002104 PR:000025402 ! has plasma membrane part T cell receptor co-receptor CD8 -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000025402 ! has plasma membrane part T cell receptor co-receptor CD8 @@ -18119,7 +7179,6 @@ id: CL:0000628 name: photosynthetic cell def: "A cell that can perform photosynthesis, in which carbohydrates are synthesized from carbon dioxide and water, using light as the energy source." [TAIR:sr] comment: see PMID:21177950, The making of a photosynthetic animal. -is_a: BFO:0000040 ! material entity is_a: CL:0000003 ! native cell relationship: capable_of GO:0015979 ! photosynthesis @@ -18161,6 +7220,7 @@ xref: FMA:67763 is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000057 ! fibroblast is_a: CL:0000327 ! extracellular matrix secreting cell +is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0002320 ! connective tissue cell intersection_of: part_of UBERON:0002107 ! liver intersection_of: RO:0002104 PR:000007939 ! has plasma membrane part glial fibrillary acidic protein @@ -18408,9 +7468,9 @@ xref: FMA:18645 is_a: CARO:0000000 ! anatomical entity is_a: CL:0000023 {is_inferred="true"} ! oocyte intersection_of: CL:0000023 ! oocyte -intersection_of: has_not_completed GO:0051321 ! meiotic cell cycle +intersection_of: CL:4030044 GO:0051321 ! has_not_completed meiotic cell cycle +relationship: CL:4030044 GO:0051321 ! has_not_completed meiotic cell cycle relationship: develops_from CL:0000024 ! oogonial cell -relationship: has_not_completed GO:0051321 ! meiotic cell cycle relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] @@ -18423,9 +7483,9 @@ xref: FMA:18646 is_a: CARO:0000000 ! anatomical entity is_a: CL:0000023 {is_inferred="true"} ! oocyte intersection_of: CL:0000023 ! oocyte -intersection_of: has_not_completed GO:0007147 ! female meiosis II +intersection_of: CL:4030044 GO:0007147 ! has_not_completed female meiosis II +relationship: CL:4030044 GO:0007147 ! has_not_completed female meiosis II relationship: develops_from CL:0000654 ! primary oocyte -relationship: has_not_completed GO:0007147 ! female meiosis II [Term] id: CL:0000656 @@ -18608,7 +7668,6 @@ is_a: CL:0000378 ! supporting cell (sensu Nematoda and Protostomia) id: CL:0000677 name: gut absorptive cell def: "Cell of the intestinal epithelium with a brush border made up of many parallel packed microvilli; associated with absorption, particularly of macromolecules." [JB:jb] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000212 ! absorptive cell relationship: part_of UBERON:0001277 ! intestinal epithelium @@ -18967,7 +8026,6 @@ id: CL:0000718 name: compound eye cone cell synonym: "cone cell (sensu Endopterygota)" RELATED [] xref: FBbt:00004193 -is_a: BFO:0000004 ! independent continuant is_a: CL:0000306 ! crystallin accumulating cell relationship: part_of UBERON:0000018 ! compound eye @@ -19017,7 +8075,6 @@ is_a: CL:0000725 ! nitrogen fixing cell [Term] id: CL:0000725 name: nitrogen fixing cell -is_a: BFO:0000040 ! material entity is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: capable_of GO:0009399 ! nitrogen fixation @@ -19365,7 +8422,6 @@ id: CL:0000762 name: nucleated thrombocyte def: "A nucleated blood cell involved in coagulation, typically seen in birds and other non-mammalian vertebrates." [GOC:add, GOC:tfm, PMID:16360205] comment: Note that this is a non-mammalian cell type. Use platelet ; CL:0000233 for thrombocytes (platelets) in mammals. -is_a: BFO:0000040 ! material entity is_a: CL:0000226 ! single nucleate cell is_a: CL:0000763 {is_inferred="true"} ! myeloid cell intersection_of: CL:0000763 ! myeloid cell @@ -19416,34 +8472,34 @@ is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: capable_of GO:0030218 ! erythrocyte differentiation +intersection_of: CL:4030045 GO:0005730 ! lacks_part nucleolus +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_part GO:0005634 ! nucleus -intersection_of: lacks_part GO:0005730 ! nucleolus -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -intersection_of: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -intersection_of: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G relationship: capable_of GO:0030218 ! erythrocyte differentiation +relationship: CL:4030045 GO:0005730 ! lacks_part nucleolus +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000547 ! proerythroblast relationship: has_part GO:0005634 ! nucleus -relationship: lacks_part GO:0005730 ! nucleolus -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -relationship: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -relationship: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -relationship: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G [Term] id: CL:0000766 @@ -19733,10 +8789,10 @@ xref: BTO:0004721 is_a: CL:0000766 ! myeloid leukocyte is_a: CL:0000990 {is_inferred="true"} ! conventional dendritic cell intersection_of: CL:0000990 ! conventional dendritic cell +intersection_of: CL:4030046 PR:000001865 ! lacks_plasma_membrane_part interleukin-3 receptor class 2 alpha chain intersection_of: develops_from CL:0000763 ! myeloid cell -intersection_of: lacks_plasma_membrane_part PR:000001865 ! interleukin-3 receptor class 2 alpha chain +relationship: CL:4030046 PR:000001865 ! lacks_plasma_membrane_part interleukin-3 receptor class 2 alpha chain relationship: develops_from CL:0000763 ! myeloid cell -relationship: lacks_plasma_membrane_part PR:000001865 ! interleukin-3 receptor class 2 alpha chain [Term] id: CL:0000783 @@ -19808,18 +8864,18 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000946 {is_inferred="true"} ! antibody secreting cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000946 ! antibody secreting cell +intersection_of: CL:4030046 GO:0019814 ! lacks_plasma_membrane_part immunoglobulin complex +intersection_of: CL:4030046 GO:0042613 ! lacks_plasma_membrane_part MHC class II protein complex +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: has_part CL:0017508 ! cartwheel heterochromatin intersection_of: has_part GO:0005794 ! Golgi apparatus -intersection_of: lacks_plasma_membrane_part GO:0019814 ! immunoglobulin complex -intersection_of: lacks_plasma_membrane_part GO:0042613 ! MHC class II protein complex -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 intersection_of: RO:0002104 PR:000001935 ! has plasma membrane part syndecan-1 +relationship: CL:4030046 GO:0019814 ! lacks_plasma_membrane_part immunoglobulin complex +relationship: CL:4030046 GO:0042613 ! lacks_plasma_membrane_part MHC class II protein complex +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: develops_from CL:0000980 ! plasmablast relationship: has_part CL:0017508 ! cartwheel heterochromatin relationship: has_part GO:0005794 ! Golgi apparatus -relationship: lacks_plasma_membrane_part GO:0019814 ! immunoglobulin complex -relationship: lacks_plasma_membrane_part GO:0042613 ! MHC class II protein complex -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001935 ! has plasma membrane part syndecan-1 @@ -19834,11 +8890,11 @@ synonym: "memory B-cell" EXACT [] synonym: "memory B-lymphocyte" EXACT [] is_a: CL:0000785 {is_inferred="true"} ! mature B cell intersection_of: CL:0000785 ! mature B cell -intersection_of: lacks_plasma_membrane_part PR:000001935 ! syndecan-1 +intersection_of: CL:4030046 PR:000001935 ! lacks_plasma_membrane_part syndecan-1 intersection_of: output_of GO:0002344 ! B cell affinity maturation intersection_of: RO:0002104 GO:0042613 ! has plasma membrane part MHC class II protein complex intersection_of: RO:0002104 PR:000001289 ! has plasma membrane part membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001935 ! syndecan-1 +relationship: CL:4030046 PR:000001935 ! lacks_plasma_membrane_part syndecan-1 relationship: output_of GO:0002344 ! B cell affinity maturation relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 GO:0042613 ! has plasma membrane part MHC class II protein complex @@ -19855,13 +8911,13 @@ synonym: "naive B-cell" EXACT [] synonym: "naive B-lymphocyte" EXACT [] is_a: CL:0000785 {is_inferred="true"} ! mature B cell intersection_of: CL:0000785 ! mature B cell -intersection_of: has_not_completed GO:0002344 ! B cell affinity maturation -intersection_of: lacks_plasma_membrane_part PR:000001963 ! CD27 molecule +intersection_of: CL:4030044 GO:0002344 ! has_not_completed B cell affinity maturation +intersection_of: CL:4030046 PR:000001963 ! lacks_plasma_membrane_part CD27 molecule intersection_of: RO:0002104 GO:0071738 ! has plasma membrane part IgD immunoglobulin complex intersection_of: RO:0002104 GO:0071753 ! has plasma membrane part IgM immunoglobulin complex intersection_of: RO:0002104 PR:000001289 ! has plasma membrane part membrane-spanning 4-domains subfamily A member 1 -relationship: has_not_completed GO:0002344 ! B cell affinity maturation -relationship: lacks_plasma_membrane_part PR:000001963 ! CD27 molecule +relationship: CL:4030044 GO:0002344 ! has_not_completed B cell affinity maturation +relationship: CL:4030046 PR:000001963 ! lacks_plasma_membrane_part CD27 molecule relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 GO:0071738 ! has plasma membrane part IgD immunoglobulin complex relationship: RO:0002104 GO:0071753 ! has plasma membrane part IgM immunoglobulin complex @@ -19892,7 +8948,7 @@ synonym: "immature alpha-beta T-lymphocyte" EXACT [] is_a: CL:0000789 {is_inferred="true"} ! alpha-beta T cell is_a: CL:0002420 ! immature T cell intersection_of: CL:0000789 ! alpha-beta T cell -intersection_of: has_not_completed GO:0045058 ! T cell selection +intersection_of: CL:4030044 GO:0045058 ! has_not_completed T cell selection [Term] id: CL:0000791 @@ -20064,10 +9120,10 @@ synonym: "immature gamma-delta T-lymphocyte" EXACT [] is_a: CL:0000798 {is_inferred="true"} ! gamma-delta T cell is_a: CL:0002420 ! immature T cell intersection_of: CL:0000798 ! gamma-delta T cell -intersection_of: has_not_completed GO:0042492 ! gamma-delta T cell differentiation -intersection_of: has_not_completed GO:0045058 ! T cell selection +intersection_of: CL:4030044 GO:0042492 ! has_not_completed gamma-delta T cell differentiation +intersection_of: CL:4030044 GO:0045058 ! has_not_completed T cell selection +relationship: CL:4030044 GO:0042492 ! has_not_completed gamma-delta T cell differentiation relationship: develops_from CL:0000807 ! DN3 thymocyte -relationship: has_not_completed GO:0042492 ! gamma-delta T cell differentiation [Term] id: CL:0000800 @@ -20124,10 +9180,10 @@ synonym: "IEL" BROAD [] synonym: "intraepithelial lymphocyte" BROAD [] is_a: CL:0000801 {is_inferred="true"} ! gamma-delta intraepithelial T cell intersection_of: CL:0000801 ! gamma-delta intraepithelial T cell -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain [Term] id: CL:0000805 @@ -20143,16 +9199,16 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000893 {is_inferred="true"} ! thymocyte is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000893 ! thymocyte -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001307 ! CD44 molecule -intersection_of: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001307 ! lacks_plasma_membrane_part CD44 molecule +intersection_of: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha intersection_of: RO:0002104 GO:0043384 ! has plasma membrane part pre-T cell receptor complex intersection_of: RO:0002104 PR:000025402 ! has plasma membrane part T cell receptor co-receptor CD8 intersection_of: RO:0015015 PR:000001932 ! has high plasma membrane amount signal transducer CD24 +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001307 ! lacks_plasma_membrane_part CD44 molecule +relationship: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha relationship: develops_from CL:0000808 ! DN4 thymocyte -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001307 ! CD44 molecule -relationship: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha relationship: RO:0002104 GO:0043384 ! has plasma membrane part pre-T cell receptor complex relationship: RO:0002104 PR:000025402 ! has plasma membrane part T cell receptor co-receptor CD8 relationship: RO:0015015 PR:000001932 ! has high plasma membrane amount signal transducer CD24 @@ -20175,8 +9231,8 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0002489 ! double negative thymocyte is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000893 ! thymocyte -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000025402 ! T cell receptor co-receptor CD8 +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000025402 ! lacks_plasma_membrane_part T cell receptor co-receptor CD8 intersection_of: RO:0002104 PR:000001307 ! has plasma membrane part CD44 molecule intersection_of: RO:0002104 PR:000001380 ! has plasma membrane part interleukin-2 receptor subunit alpha relationship: develops_from CL:0000894 ! DN1 thymic pro-T cell @@ -20202,13 +9258,13 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0002489 ! double negative thymocyte is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000893 ! thymocyte -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001307 ! CD44 molecule -intersection_of: lacks_plasma_membrane_part PR:000025402 ! T cell receptor co-receptor CD8 +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001307 ! lacks_plasma_membrane_part CD44 molecule +intersection_of: CL:4030046 PR:000025402 ! lacks_plasma_membrane_part T cell receptor co-receptor CD8 intersection_of: RO:0002104 GO:0043384 ! has plasma membrane part pre-T cell receptor complex intersection_of: RO:0002104 PR:000001380 ! has plasma membrane part interleukin-2 receptor subunit alpha +relationship: CL:4030046 PR:000001307 ! lacks_plasma_membrane_part CD44 molecule relationship: develops_from CL:0000806 ! DN2 thymocyte -relationship: lacks_plasma_membrane_part PR:000001307 ! CD44 molecule relationship: RO:0002104 GO:0043384 ! has plasma membrane part pre-T cell receptor complex relationship: RO:0002104 PR:000001380 ! has plasma membrane part interleukin-2 receptor subunit alpha @@ -20229,14 +9285,14 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0002489 ! double negative thymocyte is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000893 ! thymocyte -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001307 ! CD44 molecule -intersection_of: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha -intersection_of: lacks_plasma_membrane_part PR:000025402 ! T cell receptor co-receptor CD8 +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001307 ! lacks_plasma_membrane_part CD44 molecule +intersection_of: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha +intersection_of: CL:4030046 PR:000025402 ! lacks_plasma_membrane_part T cell receptor co-receptor CD8 intersection_of: RO:0002104 GO:0043384 ! has plasma membrane part pre-T cell receptor complex +relationship: CL:4030046 PR:000001307 ! lacks_plasma_membrane_part CD44 molecule +relationship: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha relationship: develops_from CL:0000807 ! DN3 thymocyte -relationship: lacks_plasma_membrane_part PR:000001307 ! CD44 molecule -relationship: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha relationship: RO:0002104 GO:0043384 ! has plasma membrane part pre-T cell receptor complex [Term] @@ -20271,11 +9327,11 @@ synonym: "SP CD4 cell" EXACT [] is_a: CL:0000790 {is_inferred="true"} ! immature alpha-beta T cell is_a: CL:0000893 ! thymocyte intersection_of: CL:0000790 ! immature alpha-beta T cell -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: part_of UBERON:0002370 ! thymus intersection_of: RO:0002104 PR:000001004 ! has plasma membrane part CD4 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: develops_from CL:0000809 ! double-positive, alpha-beta thymocyte -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain relationship: RO:0002104 PR:000001004 ! has plasma membrane part CD4 molecule [Term] @@ -20290,11 +9346,11 @@ synonym: "SP CD8 cell" EXACT [] is_a: CL:0000790 {is_inferred="true"} ! immature alpha-beta T cell is_a: CL:0000893 ! thymocyte intersection_of: CL:0000790 ! immature alpha-beta T cell -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: part_of UBERON:0002370 ! thymus intersection_of: RO:0002104 PR:000025402 ! has plasma membrane part T cell receptor co-receptor CD8 +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: develops_from CL:0000809 ! double-positive, alpha-beta thymocyte -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule relationship: RO:0002104 PR:000025402 ! has plasma membrane part T cell receptor co-receptor CD8 [Term] @@ -20375,13 +9431,13 @@ synonym: "immature B-lymphocyte" EXACT [] synonym: "newly formed B cell" EXACT [ISBN:781735149] is_a: CL:0001201 ! B cell, CD19-positive intersection_of: CL:0001201 ! B cell, CD19-positive -intersection_of: has_not_completed GO:0045190 ! isotype switching -intersection_of: lacks_plasma_membrane_part GO:0071738 ! IgD immunoglobulin complex +intersection_of: CL:4030044 GO:0045190 ! has_not_completed isotype switching +intersection_of: CL:4030046 GO:0071738 ! lacks_plasma_membrane_part IgD immunoglobulin complex intersection_of: RO:0002104 GO:0071753 ! has plasma membrane part IgM immunoglobulin complex intersection_of: RO:0002104 PR:000001289 ! has plasma membrane part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030044 GO:0045190 ! has_not_completed isotype switching +relationship: CL:4030046 GO:0071738 ! lacks_plasma_membrane_part IgD immunoglobulin complex relationship: develops_from CL:0000954 ! small pre-B-II cell -relationship: has_not_completed GO:0045190 ! isotype switching -relationship: lacks_plasma_membrane_part GO:0071738 ! IgD immunoglobulin complex relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 GO:0071753 ! has plasma membrane part IgM immunoglobulin complex relationship: RO:0002104 PR:000001289 ! has plasma membrane part membrane-spanning 4-domains subfamily A member 1 @@ -20396,10 +9452,10 @@ xref: BTO:0001133 xref: CALOHA:TS-0819 is_a: CL:0001201 {is_inferred="true"} ! B cell, CD19-positive intersection_of: CL:0001201 ! B cell, CD19-positive -intersection_of: lacks_plasma_membrane_part GO:0071753 ! IgM immunoglobulin complex +intersection_of: CL:4030046 GO:0071753 ! lacks_plasma_membrane_part IgM immunoglobulin complex intersection_of: RO:0002104 PR:000001898 ! has plasma membrane part neprilysin disjoint_from: CL:0000826 ! pro-B cell -relationship: lacks_plasma_membrane_part GO:0071753 ! IgM immunoglobulin complex +relationship: CL:4030046 GO:0071753 ! lacks_plasma_membrane_part IgM immunoglobulin complex relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001898 ! has plasma membrane part neprilysin @@ -20418,13 +9474,13 @@ synonym: "transitional stage B-cell" EXACT [] synonym: "transitional stage B-lymphocyte" EXACT [] is_a: CL:0001201 {is_inferred="true"} ! B cell, CD19-positive intersection_of: CL:0001201 ! B cell, CD19-positive -intersection_of: has_not_completed GO:0002335 ! mature B cell differentiation +intersection_of: CL:4030044 GO:0002335 ! has_not_completed mature B cell differentiation intersection_of: RO:0002104 GO:0071753 ! has plasma membrane part IgM immunoglobulin complex intersection_of: RO:0002104 PR:000001289 ! has plasma membrane part membrane-spanning 4-domains subfamily A member 1 intersection_of: RO:0015015 PR:000001408 ! has high plasma membrane amount ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 intersection_of: RO:0015015 PR:000001932 ! has high plasma membrane amount signal transducer CD24 +relationship: CL:4030044 GO:0002335 ! has_not_completed mature B cell differentiation relationship: develops_from CL:0000816 ! immature B cell -relationship: has_not_completed GO:0002335 ! mature B cell differentiation relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 GO:0071753 ! has plasma membrane part IgM immunoglobulin complex relationship: RO:0002104 PR:000001289 ! has plasma membrane part membrane-spanning 4-domains subfamily A member 1 @@ -20492,8 +9548,8 @@ synonym: "B1b B-lymphocyte" EXACT [] synonym: "B1b cell" EXACT [] is_a: CL:0000819 {is_inferred="true"} ! B-1 B cell intersection_of: CL:0000819 ! B-1 B cell -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -relationship: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 [Term] id: CL:0000822 @@ -20511,9 +9567,9 @@ synonym: "B2 B-lymphocyte" EXACT [] synonym: "B2 cell" EXACT [] is_a: CL:0000785 {is_inferred="true"} ! mature B cell intersection_of: CL:0000785 ! mature B cell -intersection_of: lacks_plasma_membrane_part PR:000001879 ! leukosialin +intersection_of: CL:4030046 PR:000001879 ! lacks_plasma_membrane_part leukosialin intersection_of: RO:0002104 PR:000001289 ! has plasma membrane part membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001879 ! leukosialin +relationship: CL:4030046 PR:000001879 ! lacks_plasma_membrane_part leukosialin relationship: RO:0002104 PR:000001289 ! has plasma membrane part membrane-spanning 4-domains subfamily A member 1 [Term] @@ -20557,15 +9613,15 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000838 {is_inferred="true"} ! lymphoid lineage restricted progenitor cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000838 ! lymphoid lineage restricted progenitor cell -intersection_of: lacks_plasma_membrane_part PR:000001874 ! KLRB1-like protein -intersection_of: lacks_plasma_membrane_part PR:000002065 ! mast/stem cell growth factor receptor +intersection_of: CL:4030046 PR:000001874 ! lacks_plasma_membrane_part KLRB1-like protein +intersection_of: CL:4030046 PR:000002065 ! lacks_plasma_membrane_part mast/stem cell growth factor receptor intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule intersection_of: RO:0002104 PR:000001015 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RA intersection_of: RO:0002104 PR:000001381 ! has plasma membrane part interleukin-2 receptor subunit beta intersection_of: RO:0002104 PR:000001898 ! has plasma membrane part neprilysin +relationship: CL:4030046 PR:000001874 ! lacks_plasma_membrane_part KLRB1-like protein +relationship: CL:4030046 PR:000002065 ! lacks_plasma_membrane_part mast/stem cell growth factor receptor relationship: develops_from CL:0000051 ! common lymphoid progenitor -relationship: lacks_plasma_membrane_part PR:000001874 ! KLRB1-like protein -relationship: lacks_plasma_membrane_part PR:000002065 ! mast/stem cell growth factor receptor relationship: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule relationship: RO:0002104 PR:000001015 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RA relationship: RO:0002104 PR:000001381 ! has plasma membrane part interleukin-2 receptor subunit beta @@ -20664,49 +9720,49 @@ is_a: CL:0000839 {is_inferred="true"} ! myeloid lineage restricted progenitor ce is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000839 ! myeloid lineage restricted progenitor cell intersection_of: capable_of GO:0060374 ! mast cell differentiation +intersection_of: CL:4030045 PR:000005307 ! lacks_part CCAAT/enhancer-binding protein alpha +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +intersection_of: CL:4030046 PR:000001963 ! lacks_plasma_membrane_part CD27 molecule +intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +intersection_of: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 +intersection_of: CL:4030046 PR:000002980 ! lacks_plasma_membrane_part lymphocyte antigen 6C2 +intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: has_part PR:000007857 ! erythroid transcription factor intersection_of: has_part PR:000007858 ! endothelial transcription factor GATA-2 -intersection_of: lacks_part PR:000005307 ! CCAAT/enhancer-binding protein alpha -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -intersection_of: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -intersection_of: lacks_plasma_membrane_part PR:000001963 ! CD27 molecule -intersection_of: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -intersection_of: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 -intersection_of: lacks_plasma_membrane_part PR:000002980 ! lymphocyte antigen 6C2 -intersection_of: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) intersection_of: RO:0002104 PR:000005178 ! has plasma membrane part CD9 molecule intersection_of: RO:0002104 PR:000016401 ! has plasma membrane part transmembrane emp24 domain-containing protein 1 intersection_of: RO:0015015 PR:000009143 ! has high plasma membrane amount integrin beta-7 intersection_of: RO:0015016 PR:000002065 ! has low plasma membrane amount mast/stem cell growth factor receptor intersection_of: RO:0015016 PR:000007431 ! has low plasma membrane amount high affinity immunoglobulin epsilon receptor subunit alpha relationship: capable_of GO:0060374 ! mast cell differentiation +relationship: CL:4030045 PR:000005307 ! lacks_part CCAAT/enhancer-binding protein alpha +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +relationship: CL:4030046 PR:000001963 ! lacks_plasma_membrane_part CD27 molecule +relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +relationship: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 +relationship: CL:4030046 PR:000002980 ! lacks_plasma_membrane_part lymphocyte antigen 6C2 +relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: develops_from CL:0002028 ! basophil mast progenitor cell relationship: has_part PR:000007857 ! erythroid transcription factor relationship: has_part PR:000007858 ! endothelial transcription factor GATA-2 -relationship: lacks_part PR:000005307 ! CCAAT/enhancer-binding protein alpha -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -relationship: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -relationship: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -relationship: lacks_plasma_membrane_part PR:000001963 ! CD27 molecule -relationship: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -relationship: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 -relationship: lacks_plasma_membrane_part PR:000002980 ! lymphocyte antigen 6C2 -relationship: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) relationship: RO:0002104 PR:000005178 ! has plasma membrane part CD9 molecule relationship: RO:0002104 PR:000016401 ! has plasma membrane part transmembrane emp24 domain-containing protein 1 relationship: RO:0015015 PR:000009143 ! has high plasma membrane amount integrin beta-7 @@ -20755,15 +9811,15 @@ xref: FMA:83524 is_a: CL:0000763 ! myeloid cell is_a: CL:0002191 {is_inferred="true"} ! granulocytopoietic cell intersection_of: CL:0002191 ! granulocytopoietic cell +intersection_of: CL:4030045 GO:0042582 ! lacks_part azurophil granule intersection_of: has_part CL:0017503 ! basophilic cytoplasm intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0000791 ! euchromatin -intersection_of: lacks_part GO:0042582 ! azurophil granule +relationship: CL:4030045 GO:0042582 ! lacks_part azurophil granule relationship: develops_from CL:0000557 ! granulocyte monocyte progenitor cell relationship: has_part CL:0017503 ! basophilic cytoplasm relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0000791 ! euchromatin -relationship: lacks_part GO:0042582 ! azurophil granule [Term] id: CL:0000836 @@ -20777,23 +9833,23 @@ is_a: CL:0000763 ! myeloid cell is_a: CL:0002191 ! granulocytopoietic cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000839 ! myeloid lineage restricted progenitor cell +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III +intersection_of: CL:4030046 PR:000001932 ! lacks_plasma_membrane_part signal transducer CD24 intersection_of: has_part CL:0017503 ! basophilic cytoplasm intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0005730 ! nucleolus intersection_of: has_part GO:0042582 ! azurophil granule -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001483 ! low affinity immunoglobulin gamma Fc region receptor III -intersection_of: lacks_plasma_membrane_part PR:000001932 ! signal transducer CD24 intersection_of: RO:0002104 PR:000001456 ! has plasma membrane part alpha-(1,3)-fucosyltransferase 4 intersection_of: RO:0002104 PR:000001892 ! has plasma membrane part CD33 molecule +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III +relationship: CL:4030046 PR:000001932 ! lacks_plasma_membrane_part signal transducer CD24 relationship: develops_from CL:0000835 ! myeloblast relationship: has_part CL:0017503 ! basophilic cytoplasm relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0005730 ! nucleolus relationship: has_part GO:0042582 ! azurophil granule -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001483 ! low affinity immunoglobulin gamma Fc region receptor III -relationship: lacks_plasma_membrane_part PR:000001932 ! signal transducer CD24 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001456 ! has plasma membrane part alpha-(1,3)-fucosyltransferase 4 relationship: RO:0002104 PR:000001892 ! has plasma membrane part CD33 molecule @@ -20810,38 +9866,39 @@ xref: BTO:0000725 xref: CALOHA:TS-0448 is_a: CARO:0000006 ! material anatomical entity is_a: CL:0008001 ! hematopoietic precursor cell +is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000988 ! hematopoietic cell intersection_of: bearer_of PATO:0001402 ! multipotent -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -intersection_of: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -intersection_of: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -intersection_of: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -intersection_of: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule disjoint_from: CL:0002032 ! hematopoietic oligopotent progenitor cell relationship: bearer_of PATO:0001402 ! multipotent +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: develops_from CL:0000037 ! hematopoietic stem cell -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -relationship: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -relationship: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -relationship: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -relationship: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -relationship: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule @@ -20940,16 +9997,16 @@ synonym: "follicular B-cell" EXACT [] synonym: "follicular B-lymphocyte" EXACT [] is_a: CL:0000822 ! B-2 B cell intersection_of: CL:0000785 ! mature B cell -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -intersection_of: lacks_plasma_membrane_part PR:000001879 ! leukosialin -intersection_of: lacks_plasma_membrane_part PR:000002037 ! complement component C1q receptor +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001879 ! lacks_plasma_membrane_part leukosialin +intersection_of: CL:4030046 PR:000002037 ! lacks_plasma_membrane_part complement component C1q receptor intersection_of: RO:0002104 GO:0071738 ! has plasma membrane part IgD immunoglobulin complex intersection_of: RO:0002104 GO:0071753 ! has plasma membrane part IgM immunoglobulin complex intersection_of: RO:0002104 PR:000001014 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RABC intersection_of: RO:0002104 PR:000001289 ! has plasma membrane part membrane-spanning 4-domains subfamily A member 1 intersection_of: RO:0002104 PR:000001338 ! has plasma membrane part complement receptor type 2 -relationship: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -relationship: lacks_plasma_membrane_part PR:000002037 ! complement component C1q receptor +relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +relationship: CL:4030046 PR:000002037 ! lacks_plasma_membrane_part complement component C1q receptor relationship: RO:0002104 GO:0071738 ! has plasma membrane part IgD immunoglobulin complex relationship: RO:0002104 GO:0071753 ! has plasma membrane part IgM immunoglobulin complex relationship: RO:0002104 PR:000001014 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RABC @@ -20997,15 +10054,15 @@ is_a: CL:0000785 {is_inferred="true"} ! mature B cell is_a: CL:2000074 ! splenocyte intersection_of: CL:0000785 ! mature B cell intersection_of: capable_of GO:0042742 ! defense response to bacterium -intersection_of: lacks_plasma_membrane_part PR:000001880 ! low affinity immunoglobulin epsilon Fc receptor -intersection_of: lacks_plasma_membrane_part PR:000002037 ! complement component C1q receptor +intersection_of: CL:4030046 PR:000001880 ! lacks_plasma_membrane_part low affinity immunoglobulin epsilon Fc receptor +intersection_of: CL:4030046 PR:000002037 ! lacks_plasma_membrane_part complement component C1q receptor intersection_of: part_of UBERON:0001251 ! marginal zone of spleen intersection_of: RO:0002104 PR:000001289 ! has plasma membrane part membrane-spanning 4-domains subfamily A member 1 intersection_of: RO:0002104 PR:000001338 ! has plasma membrane part complement receptor type 2 intersection_of: RO:0015015 GO:0071753 ! has high plasma membrane amount IgM immunoglobulin complex relationship: capable_of GO:0042742 ! defense response to bacterium -relationship: lacks_plasma_membrane_part PR:000001880 ! low affinity immunoglobulin epsilon Fc receptor -relationship: lacks_plasma_membrane_part PR:000002037 ! complement component C1q receptor +relationship: CL:4030046 PR:000001880 ! lacks_plasma_membrane_part low affinity immunoglobulin epsilon Fc receptor +relationship: CL:4030046 PR:000002037 ! lacks_plasma_membrane_part complement component C1q receptor relationship: part_of UBERON:0001251 ! marginal zone of spleen relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001289 ! has plasma membrane part membrane-spanning 4-domains subfamily A member 1 @@ -21027,7 +10084,6 @@ synonym: "ciliated olfactory sensory neuron" EXACT [] synonym: "ciliated sensory neuron" EXACT [] is_a: CL:0000064 ! ciliated cell is_a: CL:0000207 ! olfactory receptor cell -is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000207 ! olfactory receptor cell intersection_of: has_part GO:0005929 ! cilium @@ -21078,7 +10134,6 @@ id: CL:0000852 name: neuromast supporting cell def: "Neuromast support cell is a non-sensory cell of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; neuromast support cells are surrounded by neuromast mantle cells." [ISBN:0125296509] synonym: "neuromast support cell" EXACT [] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000630 ! supporting cell disjoint_from: CL:0000855 ! sensory hair cell relationship: part_of UBERON:0008904 ! neuromast @@ -21157,15 +10212,15 @@ intersection_of: CL:0000576 ! monocyte intersection_of: capable_of GO:0002548 ! monocyte chemotaxis intersection_of: capable_of GO:0006909 ! phagocytosis intersection_of: capable_of GO:0006954 ! inflammatory response -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: RO:0015015 PR:000001199 ! has high plasma membrane amount C-C chemokine receptor type 2 relationship: capable_of GO:0002548 ! monocyte chemotaxis relationship: capable_of GO:0006954 ! inflammatory response -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0015015 PR:000001199 ! has high plasma membrane amount C-C chemokine receptor type 2 @@ -21331,13 +10386,13 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000871 {is_inferred="true"} ! splenic macrophage is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000871 ! splenic macrophage -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: part_of UBERON:0001251 ! marginal zone of spleen intersection_of: RO:0002104 PR:000001806 ! has plasma membrane part C-type lectin domain family 6 member A intersection_of: RO:0002104 PR:000001884 ! has plasma membrane part macrophage receptor MARCO intersection_of: RO:0002104 PR:000001885 ! has plasma membrane part macrophage scavenger receptor types I and II intersection_of: RO:0002104 PR:000006172 ! has plasma membrane part CD209 molecule-like protein B -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: part_of UBERON:0001251 ! marginal zone of spleen relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001806 ! has plasma membrane part C-type lectin domain family 6 member A @@ -21355,12 +10410,12 @@ is_a: CL:0000871 {is_inferred="true"} ! splenic macrophage is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000871 ! splenic macrophage intersection_of: adjacent_to UBERON:0001959 ! white pulp of spleen -intersection_of: lacks_plasma_membrane_part PR:000001813 ! adhesion G protein-coupled receptor E1 +intersection_of: CL:4030046 PR:000001813 ! lacks_plasma_membrane_part adhesion G protein-coupled receptor E1 intersection_of: part_of UBERON:0001251 ! marginal zone of spleen intersection_of: RO:0002104 PR:000001931 ! has plasma membrane part sialoadhesin intersection_of: RO:0015016 PR:000001806 ! has low plasma membrane amount C-type lectin domain family 6 member A relationship: adjacent_to UBERON:0001959 ! white pulp of spleen -relationship: lacks_plasma_membrane_part PR:000001813 ! adhesion G protein-coupled receptor E1 +relationship: CL:4030046 PR:000001813 ! lacks_plasma_membrane_part adhesion G protein-coupled receptor E1 relationship: part_of UBERON:0001251 ! marginal zone of spleen relationship: RO:0002104 PR:000001931 ! has plasma membrane part sialoadhesin relationship: RO:0015016 PR:000001806 ! has low plasma membrane amount C-type lectin domain family 6 member A @@ -21377,7 +10432,7 @@ is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000871 ! splenic macrophage intersection_of: capable_of GO:0006955 ! immune response intersection_of: capable_of GO:0034102 ! erythrocyte clearance -intersection_of: lacks_plasma_membrane_part PR:000001013 ! integrin alpha-X +intersection_of: CL:4030046 PR:000001013 ! lacks_plasma_membrane_part integrin alpha-X intersection_of: part_of UBERON:0001250 ! red pulp of spleen intersection_of: RO:0002104 PR:000001806 ! has plasma membrane part C-type lectin domain family 6 member A intersection_of: RO:0002104 PR:000001813 ! has plasma membrane part adhesion G protein-coupled receptor E1 @@ -21386,7 +10441,7 @@ intersection_of: RO:0002104 PR:000002972 ! has plasma membrane part macrophage m intersection_of: RO:0015016 PR:000001012 ! has low plasma membrane amount integrin alpha-M intersection_of: RO:0015016 PR:000001931 ! has low plasma membrane amount sialoadhesin relationship: capable_of GO:0006955 ! immune response -relationship: lacks_plasma_membrane_part PR:000001013 ! integrin alpha-X +relationship: CL:4030046 PR:000001013 ! lacks_plasma_membrane_part integrin alpha-X relationship: part_of UBERON:0001250 ! red pulp of spleen relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001806 ! has plasma membrane part C-type lectin domain family 6 member A @@ -21410,17 +10465,17 @@ is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000576 ! monocyte intersection_of: bearer_of PATO:0000587 ! decreased size intersection_of: capable_of GO:0031294 ! lymphocyte costimulation -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: output_of GO:0030224 ! monocyte differentiation intersection_of: RO:0015015 PR:000001206 ! has high plasma membrane amount CX3C chemokine receptor 1 relationship: bearer_of PATO:0000587 ! decreased size relationship: capable_of GO:0031294 ! lymphocyte costimulation +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: develops_from CL:0002393 ! intermediate monocyte -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 relationship: output_of GO:0030224 ! monocyte differentiation relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0015015 PR:000001206 ! has high plasma membrane amount CX3C chemokine receptor 1 @@ -21435,10 +10490,10 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000871 {is_inferred="true"} ! splenic macrophage is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000871 ! splenic macrophage -intersection_of: lacks_plasma_membrane_part PR:000001813 ! adhesion G protein-coupled receptor E1 +intersection_of: CL:4030046 PR:000001813 ! lacks_plasma_membrane_part adhesion G protein-coupled receptor E1 intersection_of: part_of UBERON:0001959 ! white pulp of spleen intersection_of: RO:0002104 PR:000002064 ! has plasma membrane part macrosialin -relationship: lacks_plasma_membrane_part PR:000001813 ! adhesion G protein-coupled receptor E1 +relationship: CL:4030046 PR:000001813 ! lacks_plasma_membrane_part adhesion G protein-coupled receptor E1 relationship: part_of UBERON:0001959 ! white pulp of spleen relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000002064 ! has plasma membrane part macrosialin @@ -21656,7 +10711,7 @@ xref: MESH:D060168 xref: XAO:0003159 is_a: CL:0002420 {is_inferred="true"} ! immature T cell intersection_of: CL:0000084 ! T cell -intersection_of: has_not_completed GO:0045058 ! T cell selection +intersection_of: CL:4030044 GO:0045058 ! has_not_completed T cell selection intersection_of: part_of UBERON:0002370 ! thymus relationship: part_of UBERON:0002370 ! thymus @@ -21675,15 +10730,15 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000827 {is_inferred="true"} ! pro-T cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000827 ! pro-T cell -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha intersection_of: part_of UBERON:0002370 ! thymus intersection_of: RO:0002104 PR:000001307 ! has plasma membrane part CD44 molecule +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha relationship: develops_from CL:0002425 ! early T lineage precursor -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha relationship: part_of UBERON:0002370 ! thymus relationship: RO:0002104 PR:000001307 ! has plasma membrane part CD44 molecule @@ -21702,14 +10757,14 @@ synonym: "Th0" EXACT [GOC:tfm] is_a: CL:0000624 {is_inferred="true"} ! CD4-positive, alpha-beta T cell is_a: CL:0000898 ! naive T cell intersection_of: CL:0000624 ! CD4-positive, alpha-beta T cell -intersection_of: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha +intersection_of: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha intersection_of: RO:0002104 PR:000001015 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RA intersection_of: RO:0002104 PR:000001203 ! has plasma membrane part C-C chemokine receptor type 7 intersection_of: RO:0002104 PR:000001869 ! has plasma membrane part interleukin-7 receptor subunit alpha intersection_of: RO:0015015 PR:000001318 ! has high plasma membrane amount L-selectin intersection_of: RO:0015016 PR:000001307 ! has low plasma membrane amount CD44 molecule +relationship: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha relationship: develops_from CL:0002436 ! mature CD4 single-positive thymocyte -relationship: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] @@ -21721,13 +10776,13 @@ synonym: "activated CD4-positive, alpha-beta T-cell" EXACT [] synonym: "activated CD4-positive, alpha-beta T-lymphocyte" EXACT [] is_a: CL:0000624 {is_inferred="true"} ! CD4-positive, alpha-beta T cell intersection_of: CL:0000624 ! CD4-positive, alpha-beta T cell -intersection_of: lacks_plasma_membrane_part PR:000001318 ! L-selectin -intersection_of: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha +intersection_of: CL:4030046 PR:000001318 ! lacks_plasma_membrane_part L-selectin +intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha intersection_of: RO:0002104 PR:000001343 ! has plasma membrane part CD69 molecule intersection_of: RO:0002104 PR:000001380 ! has plasma membrane part interleukin-2 receptor subunit alpha +relationship: CL:4030046 PR:000001318 ! lacks_plasma_membrane_part L-selectin +relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha relationship: develops_from CL:0000895 ! naive thymus-derived CD4-positive, alpha-beta T cell -relationship: lacks_plasma_membrane_part PR:000001318 ! L-selectin -relationship: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha relationship: RO:0002104 PR:000001343 ! has plasma membrane part CD69 molecule relationship: RO:0002104 PR:000001380 ! has plasma membrane part interleukin-2 receptor subunit alpha @@ -21790,12 +10845,12 @@ xref: MESH:D058504 is_a: CL:0000492 {is_inferred="true"} ! CD4-positive helper T cell intersection_of: CL:0000492 ! CD4-positive helper T cell intersection_of: capable_of GO:0032620 ! interleukin-17 production +intersection_of: CL:4030046 PR:000001207 ! lacks_plasma_membrane_part C-X-C chemokine receptor type 3 intersection_of: has_part PR:000003455 ! nuclear receptor ROR-gamma isoform 2 -intersection_of: lacks_plasma_membrane_part PR:000001207 ! C-X-C chemokine receptor type 3 intersection_of: RO:0002104 PR:000001202 ! has plasma membrane part C-C chemokine receptor type 6 relationship: capable_of GO:0032620 ! interleukin-17 production +relationship: CL:4030046 PR:000001207 ! lacks_plasma_membrane_part C-X-C chemokine receptor type 3 relationship: has_part PR:000003455 ! nuclear receptor ROR-gamma isoform 2 -relationship: lacks_plasma_membrane_part PR:000001207 ! C-X-C chemokine receptor type 3 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001202 ! has plasma membrane part C-C chemokine receptor type 6 @@ -21813,14 +10868,14 @@ synonym: "T.8Nve.Sp" NARROW [] is_a: CL:0000625 {is_inferred="true"} ! CD8-positive, alpha-beta T cell is_a: CL:0000898 ! naive T cell intersection_of: CL:0000625 ! CD8-positive, alpha-beta T cell -intersection_of: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha +intersection_of: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha intersection_of: RO:0002104 PR:000001015 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RA intersection_of: RO:0002104 PR:000001203 ! has plasma membrane part C-C chemokine receptor type 7 intersection_of: RO:0002104 PR:000001869 ! has plasma membrane part interleukin-7 receptor subunit alpha intersection_of: RO:0015015 PR:000001318 ! has high plasma membrane amount L-selectin intersection_of: RO:0015016 PR:000001307 ! has low plasma membrane amount CD44 molecule +relationship: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha relationship: develops_from CL:0002437 ! mature CD8 single-positive thymocyte -relationship: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] @@ -21897,10 +10952,10 @@ synonym: "central memory CD4-positive, alpha-beta T-cell" EXACT [] synonym: "central memory CD4-positive, alpha-beta T-lymphocyte" EXACT [] is_a: CL:0001204 {is_inferred="true"} ! CD4-positive, alpha-beta memory T cell, CD45RO-positive intersection_of: CL:0001204 ! CD4-positive, alpha-beta memory T cell, CD45RO-positive -intersection_of: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA -intersection_of: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha +intersection_of: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA +intersection_of: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha intersection_of: RO:0002104 PR:000001203 ! has plasma membrane part C-C chemokine receptor type 7 -relationship: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA +relationship: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA relationship: RO:0002104 PR:000001203 ! has plasma membrane part C-C chemokine receptor type 7 [Term] @@ -21919,11 +10974,11 @@ synonym: "effector memory CD4-positive, alpha-beta T-cell" EXACT [] synonym: "effector memory CD4-positive, alpha-beta T-lymphocyte" EXACT [] is_a: CL:0001204 {is_inferred="true"} ! CD4-positive, alpha-beta memory T cell, CD45RO-positive intersection_of: CL:0001204 ! CD4-positive, alpha-beta memory T cell, CD45RO-positive -intersection_of: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA -intersection_of: lacks_plasma_membrane_part PR:000001203 ! C-C chemokine receptor type 7 -intersection_of: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha -relationship: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA -relationship: lacks_plasma_membrane_part PR:000001203 ! C-C chemokine receptor type 7 +intersection_of: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA +intersection_of: CL:4030046 PR:000001203 ! lacks_plasma_membrane_part C-C chemokine receptor type 7 +intersection_of: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha +relationship: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA +relationship: CL:4030046 PR:000001203 ! lacks_plasma_membrane_part C-C chemokine receptor type 7 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] @@ -21935,15 +10990,15 @@ synonym: "activated CD8-positive, alpha-beta T-cell" EXACT [] synonym: "activated CD8-positive, alpha-beta T-lymphocyte" EXACT [] is_a: CL:0000625 {is_inferred="true"} ! CD8-positive, alpha-beta T cell intersection_of: CL:0000625 ! CD8-positive, alpha-beta T cell -intersection_of: lacks_plasma_membrane_part PR:000001203 ! C-C chemokine receptor type 7 -intersection_of: lacks_plasma_membrane_part PR:000001318 ! L-selectin -intersection_of: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha +intersection_of: CL:4030046 PR:000001203 ! lacks_plasma_membrane_part C-C chemokine receptor type 7 +intersection_of: CL:4030046 PR:000001318 ! lacks_plasma_membrane_part L-selectin +intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha intersection_of: RO:0002104 PR:000001343 ! has plasma membrane part CD69 molecule intersection_of: RO:0002104 PR:000001380 ! has plasma membrane part interleukin-2 receptor subunit alpha +relationship: CL:4030046 PR:000001203 ! lacks_plasma_membrane_part C-C chemokine receptor type 7 +relationship: CL:4030046 PR:000001318 ! lacks_plasma_membrane_part L-selectin +relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha relationship: develops_from CL:0000900 ! naive thymus-derived CD8-positive, alpha-beta T cell -relationship: lacks_plasma_membrane_part PR:000001203 ! C-C chemokine receptor type 7 -relationship: lacks_plasma_membrane_part PR:000001318 ! L-selectin -relationship: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha relationship: RO:0002104 PR:000001343 ! has plasma membrane part CD69 molecule relationship: RO:0002104 PR:000001380 ! has plasma membrane part interleukin-2 receptor subunit alpha @@ -21962,10 +11017,10 @@ synonym: "central memory CD8-positive, alpha-beta T-cell" EXACT [] synonym: "central memory CD8-positive, alpha-beta T-lymphocyte" EXACT [] is_a: CL:0001203 {is_inferred="true"} ! CD8-positive, alpha-beta memory T cell, CD45RO-positive intersection_of: CL:0001203 ! CD8-positive, alpha-beta memory T cell, CD45RO-positive -intersection_of: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA -intersection_of: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha +intersection_of: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA +intersection_of: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha intersection_of: RO:0002104 PR:000001203 ! has plasma membrane part C-C chemokine receptor type 7 -relationship: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA +relationship: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA relationship: RO:0002104 PR:000001203 ! has plasma membrane part C-C chemokine receptor type 7 [Term] @@ -21978,15 +11033,15 @@ synonym: "CD8-positive, alpha-beta cytokine secreting effector T-lymphocyte" EXA is_a: CL:0000625 {is_inferred="true"} ! CD8-positive, alpha-beta T cell intersection_of: CL:0000625 ! CD8-positive, alpha-beta T cell intersection_of: capable_of GO:0001816 ! cytokine production -intersection_of: lacks_plasma_membrane_part PR:000001318 ! L-selectin -intersection_of: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha +intersection_of: CL:4030046 PR:000001318 ! lacks_plasma_membrane_part L-selectin +intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha intersection_of: output_of GO:0030217 ! T cell differentiation intersection_of: RO:0002104 PR:000001343 ! has plasma membrane part CD69 molecule intersection_of: RO:0002104 PR:000001380 ! has plasma membrane part interleukin-2 receptor subunit alpha relationship: capable_of GO:0001816 ! cytokine production +relationship: CL:4030046 PR:000001318 ! lacks_plasma_membrane_part L-selectin +relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha relationship: develops_from CL:0000906 ! activated CD8-positive, alpha-beta T cell -relationship: lacks_plasma_membrane_part PR:000001318 ! L-selectin -relationship: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha relationship: output_of GO:0030217 ! T cell differentiation relationship: RO:0002104 PR:000001343 ! has plasma membrane part CD69 molecule relationship: RO:0002104 PR:000001380 ! has plasma membrane part interleukin-2 receptor subunit alpha @@ -22072,11 +11127,11 @@ synonym: "effector memory CD8-positive, alpha-beta T-cell" EXACT [] synonym: "effector memory CD8-positive, alpha-beta T-lymphocyte" EXACT [] is_a: CL:0001203 {is_inferred="true"} ! CD8-positive, alpha-beta memory T cell, CD45RO-positive intersection_of: CL:0001203 ! CD8-positive, alpha-beta memory T cell, CD45RO-positive -intersection_of: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA -intersection_of: lacks_plasma_membrane_part PR:000001203 ! C-C chemokine receptor type 7 -intersection_of: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha -relationship: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA -relationship: lacks_plasma_membrane_part PR:000001203 ! C-C chemokine receptor type 7 +intersection_of: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA +intersection_of: CL:4030046 PR:000001203 ! lacks_plasma_membrane_part C-C chemokine receptor type 7 +intersection_of: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha +relationship: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA +relationship: CL:4030046 PR:000001203 ! lacks_plasma_membrane_part C-C chemokine receptor type 7 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] @@ -22105,12 +11160,12 @@ synonym: "CD8-alpha-alpha-positive, alpha-beta intraepithelial T-cell" EXACT [] synonym: "CD8-alpha-alpha-positive, alpha-beta intraepithelial T-lymphocyte" EXACT [] is_a: CL:0000797 {is_inferred="true"} ! alpha-beta intraepithelial T cell intersection_of: CL:0000797 ! alpha-beta intraepithelial T cell -intersection_of: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: RO:0002104 PR:000001084 ! has plasma membrane part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: develops_from CL:0000811 ! CD8-positive, alpha-beta thymocyte -relationship: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -relationship: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001084 ! has plasma membrane part T-cell surface glycoprotein CD8 alpha chain @@ -22151,14 +11206,14 @@ xref: FMA:84793 is_a: CL:0000908 {is_inferred="true"} ! CD8-positive, alpha-beta cytokine secreting effector T cell intersection_of: CL:0000908 ! CD8-positive, alpha-beta cytokine secreting effector T cell intersection_of: capable_of GO:0032609 ! type II interferon production +intersection_of: CL:4030046 PR:000001202 ! lacks_plasma_membrane_part C-C chemokine receptor type 6 intersection_of: has_part PR:000001835 ! T-box transcription factor TBX21 intersection_of: has_part PR:000003463 ! eomesodermin -intersection_of: lacks_plasma_membrane_part PR:000001202 ! C-C chemokine receptor type 6 intersection_of: RO:0002104 PR:000001207 ! has plasma membrane part C-X-C chemokine receptor type 3 relationship: capable_of GO:0032609 ! type II interferon production +relationship: CL:4030046 PR:000001202 ! lacks_plasma_membrane_part C-C chemokine receptor type 6 relationship: has_part PR:000001835 ! T-box transcription factor TBX21 relationship: has_part PR:000003463 ! eomesodermin -relationship: lacks_plasma_membrane_part PR:000001202 ! C-C chemokine receptor type 6 relationship: RO:0002104 PR:000001207 ! has plasma membrane part C-X-C chemokine receptor type 3 [Term] @@ -22180,9 +11235,9 @@ is_a: CL:0000908 {is_inferred="true"} ! CD8-positive, alpha-beta cytokine secret is_a: CL:0001052 ! CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell intersection_of: CL:0000908 ! CD8-positive, alpha-beta cytokine secreting effector T cell intersection_of: capable_of GO:0032633 ! interleukin-4 production +intersection_of: CL:4030046 PR:000001202 ! lacks_plasma_membrane_part C-C chemokine receptor type 6 +intersection_of: CL:4030046 PR:000001207 ! lacks_plasma_membrane_part C-X-C chemokine receptor type 3 intersection_of: has_part PR:000001941 ! trans-acting T-cell-specific transcription factor GATA-3 -intersection_of: lacks_plasma_membrane_part PR:000001202 ! C-C chemokine receptor type 6 -intersection_of: lacks_plasma_membrane_part PR:000001207 ! C-X-C chemokine receptor type 3 relationship: capable_of GO:0032633 ! interleukin-4 production relationship: has_part PR:000001941 ! trans-acting T-cell-specific transcription factor GATA-3 @@ -22225,11 +11280,11 @@ synonym: "CD8-positive, CD28-negative, alpha-beta regulatory T-cell" EXACT [] synonym: "CD8-positive, CD28-negative, alpha-beta regulatory T-lymphocyte" EXACT [] is_a: CL:0000795 {is_inferred="true"} ! CD8-positive, alpha-beta regulatory T cell intersection_of: CL:0000795 ! CD8-positive, alpha-beta regulatory T cell +intersection_of: CL:4030046 PR:000001841 ! lacks_plasma_membrane_part T-cell-specific surface glycoprotein CD28 intersection_of: has_part PR:000001350 ! forkhead box protein P3 -intersection_of: lacks_plasma_membrane_part PR:000001841 ! T-cell-specific surface glycoprotein CD28 +relationship: CL:4030046 PR:000001841 ! lacks_plasma_membrane_part T-cell-specific surface glycoprotein CD28 relationship: develops_from CL:0000906 ! activated CD8-positive, alpha-beta T cell relationship: has_part PR:000001350 ! forkhead box protein P3 -relationship: lacks_plasma_membrane_part PR:000001841 ! T-cell-specific surface glycoprotein CD28 [Term] id: CL:0000921 @@ -22287,10 +11342,10 @@ synonym: "CD4-negative, CD8-negative type I NKT cell" EXACT [] synonym: "NKT.4-.Sp" NARROW [] is_a: CL:0000921 {is_inferred="true"} ! type I NK T cell intersection_of: CL:0000921 ! type I NK T cell -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain [Term] id: CL:0000925 @@ -22360,8 +11415,8 @@ synonym: "activated CD4-negative, CD8-negative type I NKT cell" EXACT [] is_a: CL:0000924 ! CD4-negative, CD8-negative type I NK T cell intersection_of: CL:0000921 ! type I NK T cell intersection_of: capable_of GO:0002369 ! T cell cytokine production -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: RO:0002104 PR:000001343 ! has plasma membrane part CD69 molecule relationship: capable_of GO:0002369 ! T cell cytokine production relationship: develops_from CL:0000924 ! CD4-negative, CD8-negative type I NK T cell @@ -22380,8 +11435,8 @@ is_a: CL:0000924 ! CD4-negative, CD8-negative type I NK T cell intersection_of: CL:0000921 ! type I NK T cell intersection_of: capable_of GO:0002827 ! positive regulation of T-helper 1 type immune response intersection_of: capable_of GO:0032609 ! type II interferon production -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: capable_of GO:0002827 ! positive regulation of T-helper 1 type immune response relationship: capable_of GO:0032609 ! type II interferon production relationship: develops_from CL:0000928 ! activated CD4-negative, CD8-negative type I NK T cell @@ -22399,8 +11454,8 @@ is_a: CL:0000924 ! CD4-negative, CD8-negative type I NK T cell intersection_of: CL:0000921 ! type I NK T cell intersection_of: capable_of GO:0002830 ! positive regulation of type 2 immune response intersection_of: capable_of GO:0032633 ! interleukin-4 production -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: capable_of GO:0002830 ! positive regulation of type 2 immune response relationship: capable_of GO:0032633 ! interleukin-4 production relationship: develops_from CL:0000928 ! activated CD4-negative, CD8-negative type I NK T cell @@ -22481,10 +11536,10 @@ synonym: "CD4-negative, CD8-negative, alpha-beta intraepithelial T-cell" EXACT [ synonym: "CD4-negative, CD8-negative, alpha-beta intraepithelial T-lymphocyte" EXACT [] is_a: CL:0000797 {is_inferred="true"} ! alpha-beta intraepithelial T cell intersection_of: CL:0000797 ! alpha-beta intraepithelial T cell -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000025403 ! T-cell surface glycoprotein CD8 alpha chain isoform 1 -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000025403 ! T-cell surface glycoprotein CD8 alpha chain isoform 1 +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000025403 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain isoform 1 +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000025403 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain isoform 1 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] @@ -22498,17 +11553,16 @@ synonym: "LMPP" EXACT [] synonym: "lymphoid-primed multipotent progenitor" EXACT [] is_a: CL:0000837 {is_inferred="true"} ! hematopoietic multipotent progenitor cell is_a: CL:0011026 ! progenitor cell -is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000837 ! hematopoietic multipotent progenitor cell intersection_of: capable_of GO:0030098 ! lymphocyte differentiation -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001460 ! glycophorin-A +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001460 ! lacks_plasma_membrane_part glycophorin-A intersection_of: RO:0002104 PR:000002001 ! has plasma membrane part receptor-type tyrosine-protein kinase FLT3 intersection_of: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor intersection_of: RO:0002104 PR:000002979 ! has plasma membrane part lymphocyte antigen 6A-2/6E-1 relationship: capable_of GO:0030098 ! lymphocyte differentiation +relationship: CL:4030046 PR:000001460 ! lacks_plasma_membrane_part glycophorin-A relationship: develops_from CL:0002035 ! Slamf1-negative multipotent progenitor cell -relationship: lacks_plasma_membrane_part PR:000001460 ! glycophorin-A relationship: RO:0002104 PR:000002001 ! has plasma membrane part receptor-type tyrosine-protein kinase FLT3 relationship: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor relationship: RO:0002104 PR:000002979 ! has plasma membrane part lymphocyte antigen 6A-2/6E-1 @@ -22545,14 +11599,14 @@ is_a: CL:0000824 ! mature natural killer cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000824 ! mature natural killer cell intersection_of: capable_of GO:0032609 ! type II interferon production +intersection_of: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III +intersection_of: CL:4030046 PR:000002015 ! lacks_plasma_membrane_part MHC class II histocompatibility antigen alpha chain DRA intersection_of: in_taxon NCBITaxon:9606 ! Homo sapiens -intersection_of: lacks_plasma_membrane_part PR:000001483 ! low affinity immunoglobulin gamma Fc region receptor III -intersection_of: lacks_plasma_membrane_part PR:000002015 ! MHC class II histocompatibility antigen alpha chain DRA intersection_of: RO:0002104 PR:000001319 ! has plasma membrane part SLAM family member 5 intersection_of: RO:0015015 PR:000001024 ! has high plasma membrane amount neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III +relationship: CL:4030046 PR:000002015 ! lacks_plasma_membrane_part MHC class II histocompatibility antigen alpha chain DRA relationship: in_taxon NCBITaxon:9606 ! Homo sapiens -relationship: lacks_plasma_membrane_part PR:000001483 ! low affinity immunoglobulin gamma Fc region receptor III -relationship: lacks_plasma_membrane_part PR:000002015 ! MHC class II histocompatibility antigen alpha chain DRA relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001319 ! has plasma membrane part SLAM family member 5 relationship: RO:0015015 PR:000001024 ! has high plasma membrane amount neural cell adhesion molecule 1 @@ -22576,13 +11630,13 @@ is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000824 ! mature natural killer cell intersection_of: capable_of GO:0001816 ! cytokine production intersection_of: capable_of GO:0042267 ! natural killer cell mediated cytotoxicity +intersection_of: CL:4030046 PR:000002015 ! lacks_plasma_membrane_part MHC class II histocompatibility antigen alpha chain DRA intersection_of: in_taxon NCBITaxon:9606 ! Homo sapiens -intersection_of: lacks_plasma_membrane_part PR:000002015 ! MHC class II histocompatibility antigen alpha chain DRA intersection_of: RO:0002104 PR:000001483 ! has plasma membrane part low affinity immunoglobulin gamma Fc region receptor III intersection_of: RO:0015016 PR:000001024 ! has low plasma membrane amount neural cell adhesion molecule 1 relationship: capable_of GO:0042267 ! natural killer cell mediated cytotoxicity +relationship: CL:4030046 PR:000002015 ! lacks_plasma_membrane_part MHC class II histocompatibility antigen alpha chain DRA relationship: in_taxon NCBITaxon:9606 ! Homo sapiens -relationship: lacks_plasma_membrane_part PR:000002015 ! MHC class II histocompatibility antigen alpha chain DRA relationship: RO:0002104 PR:000001483 ! has plasma membrane part low affinity immunoglobulin gamma Fc region receptor III relationship: RO:0015016 PR:000001024 ! has low plasma membrane amount neural cell adhesion molecule 1 @@ -22611,13 +11665,13 @@ def: "A dendritic cell arising in thymus that has the phenotype CD11c-positive, comment: In the mouse this cell expresses CD8-alpha-alpha. is_a: CL:0000990 {is_inferred="true"} ! conventional dendritic cell intersection_of: CL:0000990 ! conventional dendritic cell -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA intersection_of: part_of UBERON:0002370 ! thymus intersection_of: RO:0002104 PR:000001013 ! has plasma membrane part integrin alpha-X +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA relationship: develops_from CL:0000894 ! DN1 thymic pro-T cell -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA relationship: part_of UBERON:0002370 ! thymus relationship: RO:0002104 PR:000001013 ! has plasma membrane part integrin alpha-X @@ -22629,11 +11683,11 @@ subset: human_reference_atlas is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000784 {is_inferred="true"} ! plasmacytoid dendritic cell intersection_of: CL:0000784 ! plasmacytoid dendritic cell -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: RO:0002104 PR:000001015 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RA intersection_of: RO:0002104 PR:000001865 ! has plasma membrane part interleukin-3 receptor class 2 alpha chain +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: develops_from CL:0000894 ! DN1 thymic pro-T cell -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001015 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RA relationship: RO:0002104 PR:000001865 ! has plasma membrane part interleukin-3 receptor class 2 alpha chain @@ -22753,11 +11807,11 @@ name: preBCR-positive large pre-B-II cell def: "An preBRC-positive large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-positive, composed of surrogate light chain protein (SL), which is composed of VpreB , Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu) on the cell surface." [GO_REF:0000031, GOC:rhs, GOC:tfm, PMID:9785673] is_a: CL:0000957 {is_inferred="true"} ! large pre-B-II cell intersection_of: CL:0000957 ! large pre-B-II cell -intersection_of: has_not_completed GO:0071708 ! immunoglobulin light chain V-J recombination +intersection_of: CL:4030044 GO:0071708 ! has_not_completed immunoglobulin light chain V-J recombination intersection_of: RO:0002104 GO:0035369 ! has plasma membrane part pre-B cell receptor complex intersection_of: RO:0002104 PR:000001858 ! has plasma membrane part immunoglobulin iota chain intersection_of: RO:0002104 PR:000001859 ! has plasma membrane part immunoglobulin lambda-like polypeptide 1 -relationship: has_not_completed GO:0071708 ! immunoglobulin light chain V-J recombination +relationship: CL:4030044 GO:0071708 ! has_not_completed immunoglobulin light chain V-J recombination relationship: RO:0002104 GO:0035369 ! has plasma membrane part pre-B cell receptor complex relationship: RO:0002104 PR:000001858 ! has plasma membrane part immunoglobulin iota chain relationship: RO:0002104 PR:000001859 ! has plasma membrane part immunoglobulin lambda-like polypeptide 1 @@ -22768,14 +11822,14 @@ name: preBCR-negative large pre-B-II cell def: "A pre-BCR-negative large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-negative, composed of surrogate light chain protein (SL), which is composed of VpreB and Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu), on the cell surface, and lack a DNA rearrangement of immunoglobulin light chain genes." [GO_REF:0000031, GOC:rhs, GOC:tfm, PMID:9785673] is_a: CL:0000957 {is_inferred="true"} ! large pre-B-II cell intersection_of: CL:0000957 ! large pre-B-II cell -intersection_of: has_not_completed GO:0071708 ! immunoglobulin light chain V-J recombination -intersection_of: lacks_plasma_membrane_part GO:0035369 ! pre-B cell receptor complex -intersection_of: lacks_plasma_membrane_part PR:000001858 ! immunoglobulin iota chain -intersection_of: lacks_plasma_membrane_part PR:000001859 ! immunoglobulin lambda-like polypeptide 1 -relationship: has_not_completed GO:0071708 ! immunoglobulin light chain V-J recombination -relationship: lacks_plasma_membrane_part GO:0035369 ! pre-B cell receptor complex -relationship: lacks_plasma_membrane_part PR:000001858 ! immunoglobulin iota chain -relationship: lacks_plasma_membrane_part PR:000001859 ! immunoglobulin lambda-like polypeptide 1 +intersection_of: CL:4030044 GO:0071708 ! has_not_completed immunoglobulin light chain V-J recombination +intersection_of: CL:4030046 GO:0035369 ! lacks_plasma_membrane_part pre-B cell receptor complex +intersection_of: CL:4030046 PR:000001858 ! lacks_plasma_membrane_part immunoglobulin iota chain +intersection_of: CL:4030046 PR:000001859 ! lacks_plasma_membrane_part immunoglobulin lambda-like polypeptide 1 +relationship: CL:4030044 GO:0071708 ! has_not_completed immunoglobulin light chain V-J recombination +relationship: CL:4030046 GO:0035369 ! lacks_plasma_membrane_part pre-B cell receptor complex +relationship: CL:4030046 PR:000001858 ! lacks_plasma_membrane_part immunoglobulin iota chain +relationship: CL:4030046 PR:000001859 ! lacks_plasma_membrane_part immunoglobulin lambda-like polypeptide 1 [Term] id: CL:0000954 @@ -22785,15 +11839,15 @@ comment: Small pre-B-II cells are also reportedly CD10-positive, CD19-positive, synonym: "small pre-BII cell" EXACT [] is_a: CL:0000955 {is_inferred="true"} ! pre-B-II cell intersection_of: CL:0000955 ! pre-B-II cell +intersection_of: CL:4030046 GO:0019815 ! lacks_plasma_membrane_part B cell receptor complex +intersection_of: CL:4030046 GO:0035369 ! lacks_plasma_membrane_part pre-B cell receptor complex intersection_of: has_part PR:000003457 ! V(D)J recombination-activating protein 1 intersection_of: has_part PR:000003460 ! V(D)J recombination-activating protein 2 -intersection_of: lacks_plasma_membrane_part GO:0019815 ! B cell receptor complex -intersection_of: lacks_plasma_membrane_part GO:0035369 ! pre-B cell receptor complex intersection_of: participates_in GO:0071708 ! immunoglobulin light chain V-J recombination +relationship: CL:4030046 GO:0019815 ! lacks_plasma_membrane_part B cell receptor complex +relationship: CL:4030046 GO:0035369 ! lacks_plasma_membrane_part pre-B cell receptor complex relationship: has_part PR:000003457 ! V(D)J recombination-activating protein 1 relationship: has_part PR:000003460 ! V(D)J recombination-activating protein 2 -relationship: lacks_plasma_membrane_part GO:0019815 ! B cell receptor complex -relationship: lacks_plasma_membrane_part GO:0035369 ! pre-B cell receptor complex relationship: participates_in GO:0071708 ! immunoglobulin light chain V-J recombination [Term] @@ -22807,12 +11861,12 @@ xref: BTO:0001133 xref: CALOHA:TS-0819 is_a: CL:0000817 {is_inferred="true"} ! precursor B cell intersection_of: CL:0000817 ! precursor B cell -intersection_of: lacks_part PR:000006611 ! DNA nucleotidylexotransferase -intersection_of: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule +intersection_of: CL:4030045 PR:000006611 ! lacks_part DNA nucleotidylexotransferase +intersection_of: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule intersection_of: output_of GO:0071707 ! immunoglobulin heavy chain V-D-J recombination disjoint_from: CL:0000956 ! pre-B-I cell -relationship: lacks_part PR:000006611 ! DNA nucleotidylexotransferase -relationship: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule +relationship: CL:4030045 PR:000006611 ! lacks_part DNA nucleotidylexotransferase +relationship: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule relationship: output_of GO:0071707 ! immunoglobulin heavy chain V-D-J recombination [Term] @@ -22848,11 +11902,11 @@ synonym: "large pre-B cell" BROAD [PMID:11244048] synonym: "large pre-BII cell" EXACT [] is_a: CL:0000955 {is_inferred="true"} ! pre-B-II cell intersection_of: CL:0000955 ! pre-B-II cell -intersection_of: lacks_part PR:000003457 ! V(D)J recombination-activating protein 1 -intersection_of: lacks_part PR:000003460 ! V(D)J recombination-activating protein 2 +intersection_of: CL:4030045 PR:000003457 ! lacks_part V(D)J recombination-activating protein 1 +intersection_of: CL:4030045 PR:000003460 ! lacks_part V(D)J recombination-activating protein 2 intersection_of: participates_in GO:0046651 ! lymphocyte proliferation -relationship: lacks_part PR:000003457 ! V(D)J recombination-activating protein 1 -relationship: lacks_part PR:000003460 ! V(D)J recombination-activating protein 2 +relationship: CL:4030045 PR:000003457 ! lacks_part V(D)J recombination-activating protein 1 +relationship: CL:4030045 PR:000003460 ! lacks_part V(D)J recombination-activating protein 2 relationship: participates_in GO:0046651 ! lymphocyte proliferation [Term] @@ -22866,15 +11920,15 @@ synonym: "T1 B-lymphocyte" EXACT [] synonym: "transitional stage 1 B cell" EXACT [] is_a: CL:0000818 {is_inferred="true"} ! transitional stage B cell intersection_of: CL:0000818 ! transitional stage B cell -intersection_of: lacks_plasma_membrane_part GO:0071738 ! IgD immunoglobulin complex -intersection_of: lacks_plasma_membrane_part PR:000001318 ! L-selectin -intersection_of: lacks_plasma_membrane_part PR:000001338 ! complement receptor type 2 -intersection_of: lacks_plasma_membrane_part PR:000001880 ! low affinity immunoglobulin epsilon Fc receptor +intersection_of: CL:4030046 GO:0071738 ! lacks_plasma_membrane_part IgD immunoglobulin complex +intersection_of: CL:4030046 PR:000001318 ! lacks_plasma_membrane_part L-selectin +intersection_of: CL:4030046 PR:000001338 ! lacks_plasma_membrane_part complement receptor type 2 +intersection_of: CL:4030046 PR:000001880 ! lacks_plasma_membrane_part low affinity immunoglobulin epsilon Fc receptor intersection_of: RO:0002104 PR:000002037 ! has plasma membrane part complement component C1q receptor -relationship: lacks_plasma_membrane_part GO:0071738 ! IgD immunoglobulin complex -relationship: lacks_plasma_membrane_part PR:000001318 ! L-selectin -relationship: lacks_plasma_membrane_part PR:000001338 ! complement receptor type 2 -relationship: lacks_plasma_membrane_part PR:000001880 ! low affinity immunoglobulin epsilon Fc receptor +relationship: CL:4030046 GO:0071738 ! lacks_plasma_membrane_part IgD immunoglobulin complex +relationship: CL:4030046 PR:000001318 ! lacks_plasma_membrane_part L-selectin +relationship: CL:4030046 PR:000001338 ! lacks_plasma_membrane_part complement receptor type 2 +relationship: CL:4030046 PR:000001880 ! lacks_plasma_membrane_part low affinity immunoglobulin epsilon Fc receptor relationship: RO:0002104 PR:000002037 ! has plasma membrane part complement component C1q receptor [Term] @@ -22888,14 +11942,14 @@ synonym: "T2 B-lymphocyte" EXACT [] synonym: "transitional stage 2 B cell" EXACT [] is_a: CL:0000818 {is_inferred="true"} ! transitional stage B cell intersection_of: CL:0000818 ! transitional stage B cell -intersection_of: lacks_plasma_membrane_part PR:000001318 ! L-selectin +intersection_of: CL:4030046 PR:000001318 ! lacks_plasma_membrane_part L-selectin intersection_of: RO:0002104 GO:0071738 ! has plasma membrane part IgD immunoglobulin complex intersection_of: RO:0002104 GO:0071753 ! has plasma membrane part IgM immunoglobulin complex intersection_of: RO:0002104 PR:000001338 ! has plasma membrane part complement receptor type 2 intersection_of: RO:0002104 PR:000001880 ! has plasma membrane part low affinity immunoglobulin epsilon Fc receptor intersection_of: RO:0002104 PR:000002037 ! has plasma membrane part complement component C1q receptor +relationship: CL:4030046 PR:000001318 ! lacks_plasma_membrane_part L-selectin relationship: develops_from CL:0000958 ! T1 B cell -relationship: lacks_plasma_membrane_part PR:000001318 ! L-selectin relationship: RO:0002104 GO:0071738 ! has plasma membrane part IgD immunoglobulin complex relationship: RO:0002104 PR:000001338 ! has plasma membrane part complement receptor type 2 relationship: RO:0002104 PR:000001880 ! has plasma membrane part low affinity immunoglobulin epsilon Fc receptor @@ -22936,10 +11990,10 @@ synonym: "Bm1 B-lymphocyte" EXACT [] is_a: CL:0000843 {is_inferred="true"} ! follicular B cell is_a: CL:0002056 ! fraction F mature B cell intersection_of: CL:0000843 ! follicular B cell -intersection_of: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 -intersection_of: lacks_plasma_membrane_part PR:000001880 ! low affinity immunoglobulin epsilon Fc receptor +intersection_of: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +intersection_of: CL:4030046 PR:000001880 ! lacks_plasma_membrane_part low affinity immunoglobulin epsilon Fc receptor intersection_of: RO:0002104 GO:0071738 ! has plasma membrane part IgD immunoglobulin complex -relationship: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +relationship: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 [Term] id: CL:0000962 @@ -22967,11 +12021,11 @@ synonym: "Bm3-delta B-cell" EXACT [] synonym: "Bm3-delta B-lymphocyte" EXACT [] is_a: CL:0000844 {is_inferred="true"} ! germinal center B cell intersection_of: CL:0000844 ! germinal center B cell -intersection_of: lacks_plasma_membrane_part GO:0071753 ! IgM immunoglobulin complex +intersection_of: CL:4030046 GO:0071753 ! lacks_plasma_membrane_part IgM immunoglobulin complex intersection_of: RO:0002104 GO:0071738 ! has plasma membrane part IgD immunoglobulin complex intersection_of: RO:0002104 PR:000001408 ! has plasma membrane part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +relationship: CL:4030046 GO:0071753 ! lacks_plasma_membrane_part IgM immunoglobulin complex relationship: develops_from CL:0000965 ! Bm3 B cell -relationship: lacks_plasma_membrane_part GO:0071753 ! IgM immunoglobulin complex relationship: RO:0002104 GO:0071738 ! has plasma membrane part IgD immunoglobulin complex relationship: RO:0002104 PR:000001408 ! has plasma membrane part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 @@ -22988,12 +12042,12 @@ synonym: "germinal center founder cell" RELATED [] is_a: CL:0000844 {is_inferred="true"} ! germinal center B cell intersection_of: CL:0000844 ! germinal center B cell intersection_of: capable_of GO:0002634 ! regulation of germinal center formation -intersection_of: lacks_plasma_membrane_part PR:000001880 ! low affinity immunoglobulin epsilon Fc receptor +intersection_of: CL:4030046 PR:000001880 ! lacks_plasma_membrane_part low affinity immunoglobulin epsilon Fc receptor intersection_of: RO:0002104 GO:0071738 ! has plasma membrane part IgD immunoglobulin complex intersection_of: RO:0002104 PR:000001408 ! has plasma membrane part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 relationship: capable_of GO:0002634 ! regulation of germinal center formation +relationship: CL:4030046 PR:000001880 ! lacks_plasma_membrane_part low affinity immunoglobulin epsilon Fc receptor relationship: develops_from CL:0000962 ! Bm2 B cell -relationship: lacks_plasma_membrane_part PR:000001880 ! low affinity immunoglobulin epsilon Fc receptor relationship: RO:0002104 GO:0071738 ! has plasma membrane part IgD immunoglobulin complex relationship: RO:0002104 PR:000001408 ! has plasma membrane part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 @@ -23009,12 +12063,12 @@ synonym: "centroblast" RELATED [PMID:8006591] is_a: CL:0000844 {is_inferred="true"} ! germinal center B cell intersection_of: CL:0000844 ! germinal center B cell intersection_of: capable_of GO:0016446 ! somatic hypermutation of immunoglobulin genes -intersection_of: lacks_plasma_membrane_part GO:0071738 ! IgD immunoglobulin complex +intersection_of: CL:4030046 GO:0071738 ! lacks_plasma_membrane_part IgD immunoglobulin complex intersection_of: RO:0002104 PR:000001408 ! has plasma membrane part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 intersection_of: RO:0002104 PR:000003516 ! has plasma membrane part lactosylceramide 4-alpha-galactosyltransferase relationship: capable_of GO:0016446 ! somatic hypermutation of immunoglobulin genes +relationship: CL:4030046 GO:0071738 ! lacks_plasma_membrane_part IgD immunoglobulin complex relationship: develops_from CL:0000964 ! Bm2' B cell -relationship: lacks_plasma_membrane_part GO:0071738 ! IgD immunoglobulin complex relationship: RO:0002104 PR:000001408 ! has plasma membrane part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 relationship: RO:0002104 PR:000003516 ! has plasma membrane part lactosylceramide 4-alpha-galactosyltransferase @@ -23029,13 +12083,13 @@ synonym: "Bm4 B-lymphocyte" EXACT [] synonym: "centrocyte" RELATED [PMID:17992590] is_a: CL:0000844 {is_inferred="true"} ! germinal center B cell intersection_of: CL:0000844 ! germinal center B cell -intersection_of: lacks_plasma_membrane_part GO:0071738 ! IgD immunoglobulin complex -intersection_of: lacks_plasma_membrane_part PR:000003516 ! lactosylceramide 4-alpha-galactosyltransferase +intersection_of: CL:4030046 GO:0071738 ! lacks_plasma_membrane_part IgD immunoglobulin complex +intersection_of: CL:4030046 PR:000003516 ! lacks_plasma_membrane_part lactosylceramide 4-alpha-galactosyltransferase intersection_of: output_of GO:0016446 ! somatic hypermutation of immunoglobulin genes intersection_of: RO:0002104 PR:000001408 ! has plasma membrane part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +relationship: CL:4030046 GO:0071738 ! lacks_plasma_membrane_part IgD immunoglobulin complex +relationship: CL:4030046 PR:000003516 ! lacks_plasma_membrane_part lactosylceramide 4-alpha-galactosyltransferase relationship: develops_from CL:0000963 ! Bm3-delta B cell -relationship: lacks_plasma_membrane_part GO:0071738 ! IgD immunoglobulin complex -relationship: lacks_plasma_membrane_part PR:000003516 ! lactosylceramide 4-alpha-galactosyltransferase relationship: output_of GO:0016446 ! somatic hypermutation of immunoglobulin genes relationship: RO:0002104 PR:000001408 ! has plasma membrane part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 @@ -23049,7 +12103,7 @@ synonym: "Bm5 B-cell" EXACT [] synonym: "Bm5 B-lymphocyte" EXACT [] is_a: CL:0001053 ! IgD-negative memory B cell intersection_of: CL:0000787 ! memory B cell -intersection_of: lacks_plasma_membrane_part GO:0071738 ! IgD immunoglobulin complex +intersection_of: CL:4030046 GO:0071738 ! lacks_plasma_membrane_part IgD immunoglobulin complex intersection_of: output_of GO:0002314 ! germinal center B cell differentiation intersection_of: output_of GO:0016446 ! somatic hypermutation of immunoglobulin genes relationship: develops_from CL:0000966 ! Bm4 B cell @@ -23109,17 +12163,17 @@ synonym: "unswitched memory B-cell" EXACT [] synonym: "unswitched memory B-lymphocyte" EXACT [] is_a: CL:0000787 {is_inferred="true"} ! memory B cell intersection_of: CL:0000787 ! memory B cell -intersection_of: lacks_plasma_membrane_part GO:0071735 ! IgG immunoglobulin complex -intersection_of: lacks_plasma_membrane_part GO:0071742 ! IgE immunoglobulin complex -intersection_of: lacks_plasma_membrane_part GO:0071745 ! IgA immunoglobulin complex -intersection_of: lacks_plasma_membrane_part PR:000001935 ! syndecan-1 +intersection_of: CL:4030046 GO:0071735 ! lacks_plasma_membrane_part IgG immunoglobulin complex +intersection_of: CL:4030046 GO:0071742 ! lacks_plasma_membrane_part IgE immunoglobulin complex +intersection_of: CL:4030046 GO:0071745 ! lacks_plasma_membrane_part IgA immunoglobulin complex +intersection_of: CL:4030046 PR:000001935 ! lacks_plasma_membrane_part syndecan-1 intersection_of: RO:0002104 GO:0071738 ! has plasma membrane part IgD immunoglobulin complex intersection_of: RO:0002104 GO:0071753 ! has plasma membrane part IgM immunoglobulin complex intersection_of: RO:0002104 PR:000001963 ! has plasma membrane part CD27 molecule +relationship: CL:4030046 GO:0071735 ! lacks_plasma_membrane_part IgG immunoglobulin complex +relationship: CL:4030046 GO:0071742 ! lacks_plasma_membrane_part IgE immunoglobulin complex +relationship: CL:4030046 GO:0071745 ! lacks_plasma_membrane_part IgA immunoglobulin complex relationship: develops_from CL:0000980 ! plasmablast -relationship: lacks_plasma_membrane_part GO:0071735 ! IgG immunoglobulin complex -relationship: lacks_plasma_membrane_part GO:0071742 ! IgE immunoglobulin complex -relationship: lacks_plasma_membrane_part GO:0071745 ! IgA immunoglobulin complex relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 GO:0071738 ! has plasma membrane part IgD immunoglobulin complex relationship: RO:0002104 GO:0071753 ! has plasma membrane part IgM immunoglobulin complex @@ -23139,7 +12193,7 @@ synonym: "memory IgM B-cell" EXACT [] synonym: "memory IgM B-lymphocyte" EXACT [] is_a: CL:0001053 ! IgD-negative memory B cell intersection_of: CL:0000787 ! memory B cell -intersection_of: lacks_plasma_membrane_part GO:0071738 ! IgD immunoglobulin complex +intersection_of: CL:4030046 GO:0071738 ! lacks_plasma_membrane_part IgD immunoglobulin complex intersection_of: RO:0002104 GO:0071753 ! has plasma membrane part IgM immunoglobulin complex relationship: RO:0002104 GO:0071753 ! has plasma membrane part IgM immunoglobulin complex @@ -23154,11 +12208,11 @@ synonym: "class switched memory B-cell" EXACT [] synonym: "class switched memory B-lymphocyte" EXACT [] is_a: CL:0000787 {is_inferred="true"} ! memory B cell intersection_of: CL:0000787 ! memory B cell -intersection_of: lacks_plasma_membrane_part GO:0071753 ! IgM immunoglobulin complex +intersection_of: CL:4030046 GO:0071753 ! lacks_plasma_membrane_part IgM immunoglobulin complex intersection_of: output_of GO:0045190 ! isotype switching intersection_of: RO:0002104 PR:000001963 ! has plasma membrane part CD27 molecule +relationship: CL:4030046 GO:0071753 ! lacks_plasma_membrane_part IgM immunoglobulin complex relationship: develops_from CL:0000970 ! unswitched memory B cell -relationship: lacks_plasma_membrane_part GO:0071753 ! IgM immunoglobulin complex relationship: output_of GO:0045190 ! isotype switching relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001963 ! has plasma membrane part CD27 molecule @@ -23186,15 +12240,15 @@ name: long lived plasma cell def: "A fully differentiated plasma cell that lives for years, as opposed to months, secretes immunoglobulin, and has the phenotype weakly CD19-positive, CD20-negative, CD38-negative, strongly CD138-positive, MHC Class II-negative, surface immunoglobulin-negative, IgD-negative, and strongly CXCR4-positive. The majority of these cells of this type reside in the bone marrow." [GO_REF:0000031, GOC:msz, GOC:tfm, ISBN:9780781765190, PMID:16014527] is_a: CL:0000786 {is_inferred="true"} ! plasma cell intersection_of: CL:0000786 ! plasma cell -intersection_of: lacks_plasma_membrane_part GO:0019814 ! immunoglobulin complex -intersection_of: lacks_plasma_membrane_part GO:0042613 ! MHC class II protein complex -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -intersection_of: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +intersection_of: CL:4030046 GO:0019814 ! lacks_plasma_membrane_part immunoglobulin complex +intersection_of: CL:4030046 GO:0042613 ! lacks_plasma_membrane_part MHC class II protein complex +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 intersection_of: RO:0015015 PR:000001208 ! has high plasma membrane amount C-X-C chemokine receptor type 4 intersection_of: RO:0015015 PR:000001935 ! has high plasma membrane amount syndecan-1 intersection_of: RO:0015016 PR:000001002 ! has low plasma membrane amount CD19 molecule +relationship: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 relationship: develops_from CL:0000975 ! short lived plasma cell -relationship: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 relationship: RO:0015015 PR:000001208 ! has high plasma membrane amount C-X-C chemokine receptor type 4 relationship: RO:0015015 PR:000001935 ! has high plasma membrane amount syndecan-1 relationship: RO:0015016 PR:000001002 ! has low plasma membrane amount CD19 molecule @@ -23263,14 +12317,14 @@ xref: FMA:84371 is_a: CL:0000785 {is_inferred="true"} ! mature B cell is_a: CL:0000946 ! antibody secreting cell intersection_of: CL:0000785 ! mature B cell -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -intersection_of: lacks_plasma_membrane_part PR:000001935 ! syndecan-1 +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001935 ! lacks_plasma_membrane_part syndecan-1 intersection_of: produces GO:0042571 ! immunoglobulin complex, circulating intersection_of: RO:0015015 PR:000001408 ! has high plasma membrane amount ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 intersection_of: RO:0015015 PR:000001963 ! has high plasma membrane amount CD27 molecule +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001935 ! lacks_plasma_membrane_part syndecan-1 relationship: develops_from CL:0000785 ! mature B cell -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001935 ! syndecan-1 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0015015 PR:000001408 ! has high plasma membrane amount ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 relationship: RO:0015015 PR:000001963 ! has high plasma membrane amount CD27 molecule @@ -23288,9 +12342,9 @@ synonym: "double negative memory B-cell" EXACT [] synonym: "double negative memory B-lymphocyte" EXACT [] is_a: CL:0001053 ! IgD-negative memory B cell intersection_of: CL:0000787 ! memory B cell -intersection_of: lacks_plasma_membrane_part GO:0071738 ! IgD immunoglobulin complex -intersection_of: lacks_plasma_membrane_part PR:000001963 ! CD27 molecule -relationship: lacks_plasma_membrane_part PR:000001963 ! CD27 molecule +intersection_of: CL:4030046 GO:0071738 ! lacks_plasma_membrane_part IgD immunoglobulin complex +intersection_of: CL:4030046 PR:000001963 ! lacks_plasma_membrane_part CD27 molecule +relationship: CL:4030046 PR:000001963 ! lacks_plasma_membrane_part CD27 molecule [Term] id: CL:0000982 @@ -23368,11 +12422,11 @@ comment: Originally described in the dendritic cell ontology (DC_CL:0000001)(PMI is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000784 {is_inferred="true"} ! plasmacytoid dendritic cell intersection_of: CL:0000784 ! plasmacytoid dendritic cell -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: RO:0002104 PR:000001014 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RABC intersection_of: RO:0002104 PR:000002978 ! has plasma membrane part lymphocyte antigen 6G intersection_of: RO:0015016 PR:000001013 ! has low plasma membrane amount integrin alpha-X -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: RO:0002104 PR:000001014 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RABC relationship: RO:0002104 PR:000002978 ! has plasma membrane part lymphocyte antigen 6G relationship: RO:0015016 PR:000001013 ! has low plasma membrane amount integrin alpha-X @@ -23457,11 +12511,11 @@ comment: Originally described in the dendritic cell ontology (DC_CL:0000008)(PMI is_a: CL:0000991 {is_inferred="true"} ! CD11c-negative plasmacytoid dendritic cell intersection_of: CL:0000991 ! CD11c-negative plasmacytoid dendritic cell intersection_of: capable_of GO:0019882 ! antigen processing and presentation -intersection_of: lacks_plasma_membrane_part PR:000001438 ! CD80 molecule +intersection_of: CL:4030046 PR:000001438 ! lacks_plasma_membrane_part CD80 molecule intersection_of: RO:0015016 GO:0042613 ! has low plasma membrane amount MHC class II protein complex intersection_of: RO:0015016 PR:000001412 ! has low plasma membrane amount CD86 molecule +relationship: CL:4030046 PR:000001438 ! lacks_plasma_membrane_part CD80 molecule relationship: develops_from CL:0000995 ! CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor -relationship: lacks_plasma_membrane_part PR:000001438 ! CD80 molecule relationship: RO:0015016 GO:0042613 ! has low plasma membrane amount MHC class II protein complex relationship: RO:0015016 PR:000001412 ! has low plasma membrane amount CD86 molecule @@ -23514,15 +12568,15 @@ is_a: CL:0000766 ! myeloid leukocyte is_a: CL:0000990 {is_inferred="true"} ! conventional dendritic cell intersection_of: CL:0000990 ! conventional dendritic cell intersection_of: capable_of GO:0002474 ! antigen processing and presentation of peptide antigen via MHC class I -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: RO:0002104 PR:000001026 ! has plasma membrane part lymphocyte antigen 75 relationship: capable_of GO:0002474 ! antigen processing and presentation of peptide antigen via MHC class I +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: develops_from CL:0002010 ! pre-conventional dendritic cell -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain relationship: RO:0002104 PR:000001026 ! has plasma membrane part lymphocyte antigen 75 [Term] @@ -23536,13 +12590,13 @@ is_a: CL:0002465 ! CD11b-positive dendritic cell intersection_of: CL:0000990 ! conventional dendritic cell intersection_of: capable_of GO:0001816 ! cytokine production intersection_of: capable_of GO:0050728 ! negative regulation of inflammatory response -intersection_of: lacks_plasma_membrane_part PR:000001026 ! lymphocyte antigen 75 -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001026 ! lacks_plasma_membrane_part lymphocyte antigen 75 +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: RO:0002104 PR:000001004 ! has plasma membrane part CD4 molecule relationship: capable_of GO:0050728 ! negative regulation of inflammatory response +relationship: CL:4030046 PR:000001026 ! lacks_plasma_membrane_part lymphocyte antigen 75 +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: develops_from CL:0002010 ! pre-conventional dendritic cell -relationship: lacks_plasma_membrane_part PR:000001026 ! lymphocyte antigen 75 -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain relationship: RO:0002104 PR:000001004 ! has plasma membrane part CD4 molecule [Term] @@ -23557,15 +12611,15 @@ intersection_of: CL:0000990 ! conventional dendritic cell intersection_of: capable_of GO:0001816 ! cytokine production intersection_of: capable_of GO:0042590 ! antigen processing and presentation of exogenous peptide antigen via MHC class I intersection_of: capable_of GO:0050729 ! positive regulation of inflammatory response -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: RO:0002104 PR:000001026 ! has plasma membrane part lymphocyte antigen 75 intersection_of: RO:0002104 PR:000001084 ! has plasma membrane part T-cell surface glycoprotein CD8 alpha chain relationship: capable_of GO:0042590 ! antigen processing and presentation of exogenous peptide antigen via MHC class I relationship: capable_of GO:0050729 ! positive regulation of inflammatory response +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: develops_from CL:0002010 ! pre-conventional dendritic cell -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M relationship: RO:0002104 PR:000001026 ! has plasma membrane part lymphocyte antigen 75 relationship: RO:0002104 PR:000001084 ! has plasma membrane part T-cell surface glycoprotein CD8 alpha chain @@ -23682,23 +12736,23 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000037 {is_inferred="true"} ! hematopoietic stem cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000037 ! hematopoietic stem cell -intersection_of: lacks_plasma_membrane_part PR:000001014 ! receptor-type tyrosine-protein phosphatase C isoform CD45RABC -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001308 ! CD48 molecule -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -intersection_of: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -intersection_of: lacks_plasma_membrane_part PR:000001896 ! natural killer cell receptor 2B4 -intersection_of: lacks_plasma_membrane_part PR:000002977 ! killer cell lectin-like receptor subfamily B member 1C -intersection_of: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) +intersection_of: CL:4030046 PR:000001014 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RABC +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001308 ! lacks_plasma_membrane_part CD48 molecule +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +intersection_of: CL:4030046 PR:000001896 ! lacks_plasma_membrane_part natural killer cell receptor 2B4 +intersection_of: CL:4030046 PR:000002977 ! lacks_plasma_membrane_part killer cell lectin-like receptor subfamily B member 1C +intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: RO:0002104 PR:000001833 ! has plasma membrane part SLAM family member 1 intersection_of: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor intersection_of: RO:0002104 PR:000002979 ! has plasma membrane part lymphocyte antigen 6A-2/6E-1 disjoint_from: CL:0001024 ! CD34-positive, CD38-negative hematopoietic stem cell -relationship: lacks_plasma_membrane_part PR:000001014 ! receptor-type tyrosine-protein phosphatase C isoform CD45RABC -relationship: lacks_plasma_membrane_part PR:000001308 ! CD48 molecule -relationship: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -relationship: lacks_plasma_membrane_part PR:000001896 ! natural killer cell receptor 2B4 -relationship: lacks_plasma_membrane_part PR:000002977 ! killer cell lectin-like receptor subfamily B member 1C +relationship: CL:4030046 PR:000001014 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RABC +relationship: CL:4030046 PR:000001308 ! lacks_plasma_membrane_part CD48 molecule +relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +relationship: CL:4030046 PR:000001896 ! lacks_plasma_membrane_part natural killer cell receptor 2B4 +relationship: CL:4030046 PR:000002977 ! lacks_plasma_membrane_part killer cell lectin-like receptor subfamily B member 1C relationship: RO:0002104 PR:000001833 ! has plasma membrane part SLAM family member 1 relationship: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor relationship: RO:0002104 PR:000002979 ! has plasma membrane part lymphocyte antigen 6A-2/6E-1 @@ -23898,15 +12952,15 @@ synonym: "CD117-positive common myeloid precursor" BROAD [] is_a: CL:0001030 ! CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor is_a: CL:0001059 {is_inferred="true"} ! common myeloid progenitor, CD34-positive intersection_of: CL:0001059 ! common myeloid progenitor, CD34-positive -intersection_of: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -intersection_of: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 +intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +intersection_of: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 intersection_of: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor intersection_of: RO:0015016 GO:0033001 ! has low plasma membrane amount Fc-gamma receptor III complex intersection_of: RO:0015016 PR:000001481 ! has low plasma membrane amount low affinity immunoglobulin gamma Fc region receptor II-b disjoint_from: CL:0001026 ! CD34-positive, CD38-positive common myeloid progenitor +relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +relationship: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 relationship: develops_from CL:0002035 ! Slamf1-negative multipotent progenitor cell -relationship: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -relationship: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 relationship: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor relationship: RO:0015016 GO:0033001 ! has low plasma membrane amount Fc-gamma receptor III complex relationship: RO:0015016 PR:000001481 ! has low plasma membrane amount low affinity immunoglobulin gamma Fc region receptor II-b @@ -23923,19 +12977,19 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000037 {is_inferred="true"} ! hematopoietic stem cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000037 ! hematopoietic stem cell -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 -intersection_of: lacks_plasma_membrane_part PR:000001483 ! low affinity immunoglobulin gamma Fc region receptor III -intersection_of: lacks_plasma_membrane_part PR:000001892 ! CD33 molecule -intersection_of: lacks_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +intersection_of: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III +intersection_of: CL:4030046 PR:000001892 ! lacks_plasma_membrane_part CD33 molecule +intersection_of: CL:4030046 PR:000001945 ! lacks_plasma_membrane_part transferrin receptor protein 1 intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule intersection_of: RO:0002104 PR:000001786 ! has plasma membrane part prominin-1 intersection_of: RO:0002104 PR:000001809 ! has plasma membrane part CD59-like glycoprotein intersection_of: RO:0002104 PR:000001843 ! has plasma membrane part Thy-1 membrane glycoprotein -relationship: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 -relationship: lacks_plasma_membrane_part PR:000001483 ! low affinity immunoglobulin gamma Fc region receptor III -relationship: lacks_plasma_membrane_part PR:000001892 ! CD33 molecule -relationship: lacks_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 +relationship: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +relationship: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III +relationship: CL:4030046 PR:000001892 ! lacks_plasma_membrane_part CD33 molecule +relationship: CL:4030046 PR:000001945 ! lacks_plasma_membrane_part transferrin receptor protein 1 relationship: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule relationship: RO:0002104 PR:000001786 ! has plasma membrane part prominin-1 relationship: RO:0002104 PR:000001809 ! has plasma membrane part CD59-like glycoprotein @@ -23954,15 +13008,15 @@ is_a: CL:0000051 {is_inferred="true"} ! common lymphoid progenitor is_a: CL:0001030 ! CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000051 ! common lymphoid progenitor -intersection_of: lacks_plasma_membrane_part PR:000001014 ! receptor-type tyrosine-protein phosphatase C isoform CD45RABC +intersection_of: CL:4030046 PR:000001014 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RABC intersection_of: RO:0002104 PR:000001869 ! has plasma membrane part interleukin-7 receptor subunit alpha intersection_of: RO:0002104 PR:000001963 ! has plasma membrane part CD27 molecule intersection_of: RO:0002104 PR:000002001 ! has plasma membrane part receptor-type tyrosine-protein kinase FLT3 intersection_of: RO:0002104 PR:000002037 ! has plasma membrane part complement component C1q receptor intersection_of: RO:0015016 PR:000002065 ! has low plasma membrane amount mast/stem cell growth factor receptor intersection_of: RO:0015016 PR:000002979 ! has low plasma membrane amount lymphocyte antigen 6A-2/6E-1 +relationship: CL:4030046 PR:000001014 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RABC relationship: develops_from CL:0000936 ! early lymphoid progenitor -relationship: lacks_plasma_membrane_part PR:000001014 ! receptor-type tyrosine-protein phosphatase C isoform CD45RABC relationship: RO:0002104 PR:000001869 ! has plasma membrane part interleukin-7 receptor subunit alpha relationship: RO:0002104 PR:000001963 ! has plasma membrane part CD27 molecule relationship: RO:0002104 PR:000002001 ! has plasma membrane part receptor-type tyrosine-protein kinase FLT3 @@ -23979,17 +13033,17 @@ synonym: "CD71-positive common myeloid precursor" NARROW [] is_a: CL:0000995 ! CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor is_a: CL:0001059 ! common myeloid progenitor, CD34-positive intersection_of: CL:0001059 ! common myeloid progenitor, CD34-positive -intersection_of: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA -intersection_of: lacks_plasma_membrane_part PR:000001836 ! CD7 molecule -intersection_of: lacks_plasma_membrane_part PR:000001867 ! interleukin-5 receptor subunit alpha -intersection_of: lacks_plasma_membrane_part PR:000001898 ! neprilysin +intersection_of: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA +intersection_of: CL:4030046 PR:000001836 ! lacks_plasma_membrane_part CD7 molecule +intersection_of: CL:4030046 PR:000001867 ! lacks_plasma_membrane_part interleukin-5 receptor subunit alpha +intersection_of: CL:4030046 PR:000001898 ! lacks_plasma_membrane_part neprilysin intersection_of: RO:0002104 PR:000001408 ! has plasma membrane part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 intersection_of: RO:0015016 PR:000001865 ! has low plasma membrane amount interleukin-3 receptor class 2 alpha chain +relationship: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA +relationship: CL:4030046 PR:000001836 ! lacks_plasma_membrane_part CD7 molecule +relationship: CL:4030046 PR:000001867 ! lacks_plasma_membrane_part interleukin-5 receptor subunit alpha +relationship: CL:4030046 PR:000001898 ! lacks_plasma_membrane_part neprilysin relationship: develops_from CL:0002043 ! CD34-positive, CD38-negative multipotent progenitor cell -relationship: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA -relationship: lacks_plasma_membrane_part PR:000001836 ! CD7 molecule -relationship: lacks_plasma_membrane_part PR:000001867 ! interleukin-5 receptor subunit alpha -relationship: lacks_plasma_membrane_part PR:000001898 ! neprilysin relationship: RO:0002104 PR:000001408 ! has plasma membrane part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 relationship: RO:0015016 PR:000001865 ! has low plasma membrane amount interleukin-3 receptor class 2 alpha chain @@ -24004,12 +13058,12 @@ is_a: CL:0000051 {is_inferred="true"} ! common lymphoid progenitor is_a: CL:0001012 ! CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000051 ! common lymphoid progenitor -intersection_of: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA -intersection_of: lacks_plasma_membrane_part PR:000001836 ! CD7 molecule +intersection_of: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA +intersection_of: CL:4030046 PR:000001836 ! lacks_plasma_membrane_part CD7 molecule intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule +relationship: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA +relationship: CL:4030046 PR:000001836 ! lacks_plasma_membrane_part CD7 molecule relationship: develops_from CL:0001021 ! CD34-positive, CD38-positive common lymphoid progenitor -relationship: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA -relationship: lacks_plasma_membrane_part PR:000001836 ! CD7 molecule relationship: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule [Term] @@ -24022,11 +13076,11 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000051 {is_inferred="true"} ! common lymphoid progenitor is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000051 ! common lymphoid progenitor -intersection_of: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA +intersection_of: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule intersection_of: RO:0002104 PR:000001836 ! has plasma membrane part CD7 molecule +relationship: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA relationship: develops_from CL:0001027 ! CD7-negative lymphoid progenitor cell -relationship: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA relationship: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule relationship: RO:0002104 PR:000001836 ! has plasma membrane part CD7 molecule @@ -24041,35 +13095,36 @@ synonym: "pro-DCs" EXACT [PMID:21219184] is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000763 ! myeloid cell is_a: CL:0001019 ! CD115-positive monocyte OR common dendritic progenitor +is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0002031 ! hematopoietic lineage restricted progenitor cell -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -intersection_of: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -intersection_of: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -intersection_of: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: RO:0002104 PR:000002001 ! has plasma membrane part receptor-type tyrosine-protein kinase FLT3 intersection_of: RO:0002104 PR:000002062 ! has plasma membrane part macrophage colony-stimulating factor 1 receptor intersection_of: RO:0015016 PR:000002065 ! has low plasma membrane amount mast/stem cell growth factor receptor +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: develops_from CL:0002009 ! macrophage dendritic cell progenitor -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -relationship: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -relationship: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -relationship: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -relationship: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) relationship: RO:0002104 PR:000002001 ! has plasma membrane part receptor-type tyrosine-protein kinase FLT3 relationship: RO:0002104 PR:000002062 ! has plasma membrane part macrophage colony-stimulating factor 1 receptor relationship: RO:0015016 PR:000002065 ! has low plasma membrane amount mast/stem cell growth factor receptor @@ -24124,7 +13179,6 @@ creation_date: 2012-01-12T09:58:38Z id: CL:0001035 name: bone cell def: "A connective tissue cell found in bone." [GO_REF:0000034, GOC:add] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000548 {is_inferred="true"} ! animal cell intersection_of: CL:0000548 ! animal cell intersection_of: part_of UBERON:0001474 ! bone element @@ -24220,12 +13274,12 @@ synonym: "effector CD4-positive, alpha-beta T-lymphocyte" EXACT [] is_a: CL:0000624 ! CD4-positive, alpha-beta T cell is_a: CL:0000911 ! effector T cell intersection_of: CL:0000911 ! effector T cell -intersection_of: lacks_plasma_membrane_part PR:000001203 ! C-C chemokine receptor type 7 -intersection_of: lacks_plasma_membrane_part PR:000025402 ! T cell receptor co-receptor CD8 +intersection_of: CL:4030046 PR:000001203 ! lacks_plasma_membrane_part C-C chemokine receptor type 7 +intersection_of: CL:4030046 PR:000025402 ! lacks_plasma_membrane_part T cell receptor co-receptor CD8 intersection_of: RO:0002104 GO:0042105 ! has plasma membrane part alpha-beta T cell receptor complex intersection_of: RO:0002104 PR:000001004 ! has plasma membrane part CD4 molecule intersection_of: RO:0002104 PR:000001015 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RA -relationship: lacks_plasma_membrane_part PR:000001203 ! C-C chemokine receptor type 7 +relationship: CL:4030046 PR:000001203 ! lacks_plasma_membrane_part C-C chemokine receptor type 7 relationship: RO:0002104 PR:000001015 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RA [Term] @@ -24240,9 +13294,9 @@ synonym: "naive CCR4-positive regulatory T-lymphocyte" EXACT [] is_a: CL:0001047 ! CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T cell is_a: CL:0002677 ! naive regulatory T cell intersection_of: CL:0002677 ! naive regulatory T cell -intersection_of: lacks_plasma_membrane_part PR:000001017 ! receptor-type tyrosine-protein phosphatase C isoform CD45RO +intersection_of: CL:4030046 PR:000001017 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RO intersection_of: RO:0002104 PR:000001200 ! has plasma membrane part C-C chemokine receptor type 4 -relationship: lacks_plasma_membrane_part PR:000001017 ! receptor-type tyrosine-protein phosphatase C isoform CD45RO +relationship: CL:4030046 PR:000001017 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RO [Term] id: CL:0001046 @@ -24319,12 +13373,12 @@ synonym: "effector CD8-positive, alpha-beta T-lymphocyte" EXACT [] is_a: CL:0000625 ! CD8-positive, alpha-beta T cell is_a: CL:0000911 ! effector T cell intersection_of: CL:0000911 ! effector T cell -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001203 ! C-C chemokine receptor type 7 +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001203 ! lacks_plasma_membrane_part C-C chemokine receptor type 7 intersection_of: RO:0002104 GO:0042105 ! has plasma membrane part alpha-beta T cell receptor complex intersection_of: RO:0002104 PR:000001015 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RA intersection_of: RO:0002104 PR:000025402 ! has plasma membrane part T cell receptor co-receptor CD8 -relationship: lacks_plasma_membrane_part PR:000001203 ! C-C chemokine receptor type 7 +relationship: CL:4030046 PR:000001203 ! lacks_plasma_membrane_part C-C chemokine receptor type 7 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001015 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RA @@ -24339,10 +13393,10 @@ synonym: "CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T-lymphocyte" synonym: "non-Th1/Th17 CD4+ T cell" BROAD [PMID:22343568] is_a: CL:0000624 ! CD4-positive, alpha-beta T cell intersection_of: CL:0000624 ! CD4-positive, alpha-beta T cell -intersection_of: lacks_plasma_membrane_part PR:000001202 ! C-C chemokine receptor type 6 -intersection_of: lacks_plasma_membrane_part PR:000001207 ! C-X-C chemokine receptor type 3 -relationship: lacks_plasma_membrane_part PR:000001202 ! C-C chemokine receptor type 6 -relationship: lacks_plasma_membrane_part PR:000001207 ! C-X-C chemokine receptor type 3 +intersection_of: CL:4030046 PR:000001202 ! lacks_plasma_membrane_part C-C chemokine receptor type 6 +intersection_of: CL:4030046 PR:000001207 ! lacks_plasma_membrane_part C-X-C chemokine receptor type 3 +relationship: CL:4030046 PR:000001202 ! lacks_plasma_membrane_part C-C chemokine receptor type 6 +relationship: CL:4030046 PR:000001207 ! lacks_plasma_membrane_part C-X-C chemokine receptor type 3 [Term] id: CL:0001052 @@ -24355,10 +13409,10 @@ synonym: "CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T-lymphocyte" synonym: "non-Tc1/Tc17 CD8+ T cell" BROAD [PMID:22343568] is_a: CL:0000625 ! CD8-positive, alpha-beta T cell intersection_of: CL:0000625 ! CD8-positive, alpha-beta T cell -intersection_of: lacks_plasma_membrane_part PR:000001202 ! C-C chemokine receptor type 6 -intersection_of: lacks_plasma_membrane_part PR:000001207 ! C-X-C chemokine receptor type 3 -relationship: lacks_plasma_membrane_part PR:000001202 ! C-C chemokine receptor type 6 -relationship: lacks_plasma_membrane_part PR:000001207 ! C-X-C chemokine receptor type 3 +intersection_of: CL:4030046 PR:000001202 ! lacks_plasma_membrane_part C-C chemokine receptor type 6 +intersection_of: CL:4030046 PR:000001207 ! lacks_plasma_membrane_part C-X-C chemokine receptor type 3 +relationship: CL:4030046 PR:000001202 ! lacks_plasma_membrane_part C-C chemokine receptor type 6 +relationship: CL:4030046 PR:000001207 ! lacks_plasma_membrane_part C-X-C chemokine receptor type 3 [Term] id: CL:0001053 @@ -24368,8 +13422,8 @@ comment: This cell type is compatible with the HIPC Lyoplate markers for 'IgD- m synonym: "IgD- memory B cell" EXACT [PMID:22343568] is_a: CL:0000787 ! memory B cell intersection_of: CL:0000787 ! memory B cell -intersection_of: lacks_plasma_membrane_part GO:0071738 ! IgD immunoglobulin complex -relationship: lacks_plasma_membrane_part GO:0071738 ! IgD immunoglobulin complex +intersection_of: CL:4030046 GO:0071738 ! lacks_plasma_membrane_part IgD immunoglobulin complex +relationship: CL:4030046 GO:0071738 ! lacks_plasma_membrane_part IgD immunoglobulin complex [Term] id: CL:0001054 @@ -24382,13 +13436,13 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000576 ! monocyte is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000576 ! monocyte -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: RO:0002104 PR:000001889 ! has plasma membrane part CD14 molecule -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001889 ! has plasma membrane part CD14 molecule @@ -24442,10 +13496,10 @@ synonym: "plasmacytoid dendritic cell" BROAD [PMID:22343568] is_a: CL:0000784 ! plasmacytoid dendritic cell is_a: CL:0001056 ! dendritic cell, human intersection_of: CL:0000784 ! plasmacytoid dendritic cell -intersection_of: lacks_plasma_membrane_part PR:000001013 ! integrin alpha-X +intersection_of: CL:4030046 PR:000001013 ! lacks_plasma_membrane_part integrin alpha-X intersection_of: RO:0002104 PR:000001865 ! has plasma membrane part interleukin-3 receptor class 2 alpha chain intersection_of: RO:0002104 PR:000002015 ! has plasma membrane part MHC class II histocompatibility antigen alpha chain DRA -relationship: lacks_plasma_membrane_part PR:000001013 ! integrin alpha-X +relationship: CL:4030046 PR:000001013 ! lacks_plasma_membrane_part integrin alpha-X relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001865 ! has plasma membrane part interleukin-3 receptor class 2 alpha chain @@ -24488,31 +13542,31 @@ def: "A hematopoietic oligopotent progenitor cell that has the ability to differ is_a: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: bearer_of PATO:0001401 ! oligopotent -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -intersection_of: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -intersection_of: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -intersection_of: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -relationship: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -relationship: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -relationship: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -relationship: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) creation_date: 2010-01-06T03:43:27Z [Term] @@ -24540,15 +13594,15 @@ synonym: "TEMRA" BROAD [PMID:15032595] is_a: CL:0000909 ! CD8-positive, alpha-beta memory T cell is_a: CL:4030002 ! effector memory CD45RA-positive, alpha-beta T cell, terminally differentiated intersection_of: CL:0000909 ! CD8-positive, alpha-beta memory T cell +intersection_of: CL:4030046 PR:000001017 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RO +intersection_of: CL:4030046 PR:000001203 ! lacks_plasma_membrane_part C-C chemokine receptor type 7 intersection_of: in_taxon NCBITaxon:9606 ! Homo sapiens -intersection_of: lacks_plasma_membrane_part PR:000001017 ! receptor-type tyrosine-protein phosphatase C isoform CD45RO -intersection_of: lacks_plasma_membrane_part PR:000001203 ! C-C chemokine receptor type 7 intersection_of: output_of GO:0043379 ! memory T cell differentiation intersection_of: RO:0002104 PR:000001015 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RA +relationship: CL:4030046 PR:000001017 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RO +relationship: CL:4030046 PR:000001203 ! lacks_plasma_membrane_part C-C chemokine receptor type 7 relationship: develops_from CL:0000913 ! effector memory CD8-positive, alpha-beta T cell relationship: in_taxon NCBITaxon:9606 ! Homo sapiens -relationship: lacks_plasma_membrane_part PR:000001017 ! receptor-type tyrosine-protein phosphatase C isoform CD45RO -relationship: lacks_plasma_membrane_part PR:000001203 ! C-C chemokine receptor type 7 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001015 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RA @@ -24590,13 +13644,13 @@ is_a: CL:0000542 ! lymphocyte intersection_of: CL:0000542 ! lymphocyte intersection_of: capable_of GO:0001816 ! cytokine production intersection_of: capable_of GO:0045087 ! innate immune response -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: capable_of GO:0001816 ! cytokine production relationship: capable_of GO:0045087 ! innate immune response +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: dc-contributor https://orcid.org/0000-0001-9990-8331 -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: dcterms-date "2017-01-30T20:20:48Z" xsd:dateTime @@ -24616,30 +13670,30 @@ is_a: CL:0000038 ! erythroid progenitor cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000038 ! erythroid progenitor cell intersection_of: capable_of GO:0030218 ! erythrocyte differentiation -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -intersection_of: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -intersection_of: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 relationship: capable_of GO:0030218 ! erythrocyte differentiation -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -relationship: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -relationship: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -relationship: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 [Term] @@ -24722,12 +13776,12 @@ is_a: CL:0001082 ! immature innate lymphoid cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0001065 ! innate lymphoid cell intersection_of: bearer_of PATO:0001501 ! immature +intersection_of: CL:4030046 PR:P28906 ! lacks_plasma_membrane_part hematopoietic progenitor cell antigen CD34 (human) intersection_of: in_taxon NCBITaxon:9606 ! Homo sapiens -intersection_of: lacks_plasma_membrane_part PR:P28906 ! hematopoietic progenitor cell antigen CD34 (human) intersection_of: RO:0002104 PR:P10721 ! has plasma membrane part mast/stem cell growth factor receptor Kit (human) +relationship: CL:4030046 PR:P28906 ! lacks_plasma_membrane_part hematopoietic progenitor cell antigen CD34 (human) relationship: develops_from CL:0001074 ! CD34-positive, CD56-positive, CD117-positive common innate lymphoid precursor, human relationship: in_taxon NCBITaxon:9606 ! Homo sapiens -relationship: lacks_plasma_membrane_part PR:P28906 ! hematopoietic progenitor cell antigen CD34 (human) relationship: RO:0002104 PR:P10721 ! has plasma membrane part mast/stem cell growth factor receptor Kit (human) [Term] @@ -24833,10 +13887,10 @@ name: NKp44-negative group 3 innate lymphoid cell, human def: "A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive, and NKp44-negative." [GOC:add, PMID:24778151, PMID:31500958] is_a: CL:0001078 ! group 3 innate lymphoid cell, human intersection_of: CL:0001071 ! group 3 innate lymphoid cell +intersection_of: CL:4030046 PR:O95944 ! lacks_plasma_membrane_part natural cytotoxicity triggering receptor 2 (human) intersection_of: in_taxon NCBITaxon:9606 ! Homo sapiens -intersection_of: lacks_plasma_membrane_part PR:O95944 ! natural cytotoxicity triggering receptor 2 (human) intersection_of: RO:0002104 PR:P16871 ! has plasma membrane part interleukin-7 receptor subunit alpha (human) -relationship: lacks_plasma_membrane_part PR:O95944 ! natural cytotoxicity triggering receptor 2 (human) +relationship: CL:4030046 PR:O95944 ! lacks_plasma_membrane_part natural cytotoxicity triggering receptor 2 (human) [Term] id: CL:0001081 @@ -24882,16 +13936,16 @@ synonym: "TEMRA" BROAD [PMID:17465678] is_a: CL:0000897 ! CD4-positive, alpha-beta memory T cell is_a: CL:4030002 ! effector memory CD45RA-positive, alpha-beta T cell, terminally differentiated intersection_of: CL:0000897 ! CD4-positive, alpha-beta memory T cell +intersection_of: CL:4030046 PR:000001017 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RO +intersection_of: CL:4030046 PR:000001203 ! lacks_plasma_membrane_part C-C chemokine receptor type 7 intersection_of: in_taxon NCBITaxon:9606 ! Homo sapiens -intersection_of: lacks_plasma_membrane_part PR:000001017 ! receptor-type tyrosine-protein phosphatase C isoform CD45RO -intersection_of: lacks_plasma_membrane_part PR:000001203 ! C-C chemokine receptor type 7 intersection_of: output_of GO:0043379 ! memory T cell differentiation intersection_of: RO:0002104 PR:000001015 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RA +relationship: CL:4030046 PR:000001017 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RO +relationship: CL:4030046 PR:000001203 ! lacks_plasma_membrane_part C-C chemokine receptor type 7 relationship: dc-contributor https://orcid.org/0000-0001-9990-8331 relationship: develops_from CL:0000905 ! effector memory CD4-positive, alpha-beta T cell relationship: in_taxon NCBITaxon:9606 ! Homo sapiens -relationship: lacks_plasma_membrane_part PR:000001017 ! receptor-type tyrosine-protein phosphatase C isoform CD45RO -relationship: lacks_plasma_membrane_part PR:000001203 ! C-C chemokine receptor type 7 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001015 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RA property_value: dcterms-date "2021-01-18T16:32:44Z" xsd:dateTime @@ -24905,12 +13959,12 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000945 ! lymphocyte of B lineage is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000945 ! lymphocyte of B lineage +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: in_taxon NCBITaxon:40674 ! Mammalia -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon intersection_of: RO:0002104 PR:000001002 ! has plasma membrane part CD19 molecule +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: dc-contributor https://orcid.org/0000-0001-9990-8331 relationship: in_taxon NCBITaxon:40674 ! Mammalia -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon relationship: RO:0002104 PR:000001002 ! has plasma membrane part CD19 molecule [Term] @@ -24952,15 +14006,15 @@ synonym: "CD8-positive, alpha-beta memory T-cell, CD45RO-positive" EXACT [] synonym: "CD8-positive, alpha-beta memory T-lymphocyte, CD45RO-positive" EXACT [] is_a: CL:0000909 {is_inferred="true"} ! CD8-positive, alpha-beta memory T cell intersection_of: CL:0000909 ! CD8-positive, alpha-beta memory T cell -intersection_of: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha +intersection_of: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: output_of GO:0043379 ! memory T cell differentiation intersection_of: RO:0002104 PR:000001017 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RO intersection_of: RO:0002104 PR:000001869 ! has plasma membrane part interleukin-7 receptor subunit alpha intersection_of: RO:0015015 PR:000001307 ! has high plasma membrane amount CD44 molecule intersection_of: RO:0015015 PR:000001381 ! has high plasma membrane amount interleukin-2 receptor subunit beta +relationship: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha relationship: develops_from CL:0000906 ! activated CD8-positive, alpha-beta T cell -relationship: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001017 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RO @@ -24977,15 +14031,15 @@ synonym: "CD4-positive, alpha-beta memory T-cell, CD45RO-positive" EXACT [] synonym: "CD4-positive, alpha-beta memory T-lymphocyte, CD45RO-positive" EXACT [] is_a: CL:0000897 {is_inferred="true"} ! CD4-positive, alpha-beta memory T cell intersection_of: CL:0000897 ! CD4-positive, alpha-beta memory T cell -intersection_of: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha +intersection_of: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: output_of GO:0043379 ! memory T cell differentiation intersection_of: RO:0002104 PR:000001017 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RO intersection_of: RO:0002104 PR:000001869 ! has plasma membrane part interleukin-7 receptor subunit alpha intersection_of: RO:0015015 PR:000001307 ! has high plasma membrane amount CD44 molecule intersection_of: RO:0015015 PR:000001381 ! has high plasma membrane amount interleukin-2 receptor subunit beta +relationship: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha relationship: develops_from CL:0000896 ! activated CD4-positive, alpha-beta T cell -relationship: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001017 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RO relationship: RO:0002104 PR:000001869 ! has plasma membrane part interleukin-7 receptor subunit alpha @@ -25007,22 +14061,22 @@ comment: Markers found on mouse cells. synonym: "c- Kit-positive erythroid progenitor cell" EXACT [] is_a: CL:0001066 {is_inferred="true"} ! erythroid progenitor cell, mammalian intersection_of: CL:0001066 ! erythroid progenitor cell, mammalian -intersection_of: lacks_plasma_membrane_part GO:0033001 ! Fc-gamma receptor III complex -intersection_of: lacks_plasma_membrane_part PR:000001833 ! SLAM family member 1 -intersection_of: lacks_plasma_membrane_part PR:000001865 ! interleukin-3 receptor class 2 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -intersection_of: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 -intersection_of: lacks_plasma_membrane_part PR:000009127 ! integrin alpha-IIb +intersection_of: CL:4030046 GO:0033001 ! lacks_plasma_membrane_part Fc-gamma receptor III complex +intersection_of: CL:4030046 PR:000001833 ! lacks_plasma_membrane_part SLAM family member 1 +intersection_of: CL:4030046 PR:000001865 ! lacks_plasma_membrane_part interleukin-3 receptor class 2 alpha chain +intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +intersection_of: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 +intersection_of: CL:4030046 PR:000009127 ! lacks_plasma_membrane_part integrin alpha-IIb intersection_of: RO:0002104 PR:000001345 ! has plasma membrane part endoglin intersection_of: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor +relationship: CL:4030046 GO:0033001 ! lacks_plasma_membrane_part Fc-gamma receptor III complex +relationship: CL:4030046 PR:000001833 ! lacks_plasma_membrane_part SLAM family member 1 +relationship: CL:4030046 PR:000001865 ! lacks_plasma_membrane_part interleukin-3 receptor class 2 alpha chain +relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +relationship: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 +relationship: CL:4030046 PR:000009127 ! lacks_plasma_membrane_part integrin alpha-IIb relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002006 ! Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell -relationship: lacks_plasma_membrane_part GO:0033001 ! Fc-gamma receptor III complex -relationship: lacks_plasma_membrane_part PR:000001833 ! SLAM family member 1 -relationship: lacks_plasma_membrane_part PR:000001865 ! interleukin-3 receptor class 2 alpha chain -relationship: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -relationship: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 -relationship: lacks_plasma_membrane_part PR:000009127 ! integrin alpha-IIb relationship: RO:0002104 PR:000001345 ! has plasma membrane part endoglin relationship: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor creation_date: 2010-04-26T10:14:16Z @@ -25050,20 +14104,20 @@ def: "A granulocyte monocyte progenitor that is Kit-positive, CD34-positive, Fc- comment: Markers are found on mouse cells. is_a: CL:0000557 {is_inferred="true"} ! granulocyte monocyte progenitor cell intersection_of: CL:0000557 ! granulocyte monocyte progenitor cell -intersection_of: lacks_plasma_membrane_part PR:000001206 ! CX3C chemokine receptor 1 -intersection_of: lacks_plasma_membrane_part PR:000001843 ! Thy-1 membrane glycoprotein -intersection_of: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -intersection_of: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 +intersection_of: CL:4030046 PR:000001206 ! lacks_plasma_membrane_part CX3C chemokine receptor 1 +intersection_of: CL:4030046 PR:000001843 ! lacks_plasma_membrane_part Thy-1 membrane glycoprotein +intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +intersection_of: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule intersection_of: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor intersection_of: RO:0015015 GO:0033001 ! has high plasma membrane amount Fc-gamma receptor III complex intersection_of: RO:0015015 PR:000001479 ! has high plasma membrane amount low affinity immunoglobulin gamma Fc region receptor II +relationship: CL:4030046 PR:000001206 ! lacks_plasma_membrane_part CX3C chemokine receptor 1 +relationship: CL:4030046 PR:000001843 ! lacks_plasma_membrane_part Thy-1 membrane glycoprotein +relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +relationship: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0001023 ! Kit-positive, CD34-positive common myeloid progenitor -relationship: lacks_plasma_membrane_part PR:000001206 ! CX3C chemokine receptor 1 -relationship: lacks_plasma_membrane_part PR:000001843 ! Thy-1 membrane glycoprotein -relationship: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -relationship: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 relationship: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule relationship: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor relationship: RO:0015015 GO:0033001 ! has high plasma membrane amount Fc-gamma receptor III complex @@ -25078,11 +14132,11 @@ comment: Cell markers associated with human cells. xref: FMA:83517 is_a: CL:0001066 {is_inferred="true"} ! erythroid progenitor cell, mammalian intersection_of: CL:0001066 ! erythroid progenitor cell, mammalian -intersection_of: lacks_plasma_membrane_part PR:000001460 ! glycophorin-A +intersection_of: CL:4030046 PR:000001460 ! lacks_plasma_membrane_part glycophorin-A intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule +relationship: CL:4030046 PR:000001460 ! lacks_plasma_membrane_part glycophorin-A relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002005 ! CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell -relationship: lacks_plasma_membrane_part PR:000001460 ! glycophorin-A relationship: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule creation_date: 2010-04-26T10:14:30Z @@ -25093,12 +14147,12 @@ def: "A proerythoblast that is CD34-negative and GlyA-negative." [GOC:ak, GOC:tf comment: Cell surface markers are associated with human cells. is_a: CL:0000547 {is_inferred="true"} ! proerythroblast intersection_of: CL:0000547 ! proerythroblast -intersection_of: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule -intersection_of: lacks_plasma_membrane_part PR:000001460 ! glycophorin-A +intersection_of: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule +intersection_of: CL:4030046 PR:000001460 ! lacks_plasma_membrane_part glycophorin-A +relationship: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule +relationship: CL:4030046 PR:000001460 ! lacks_plasma_membrane_part glycophorin-A relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002003 ! CD34-positive, GlyA-negative erythroid progenitor cell -relationship: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule -relationship: lacks_plasma_membrane_part PR:000001460 ! glycophorin-A creation_date: 2010-04-26T10:31:50Z [Term] @@ -25110,13 +14164,13 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000050 {is_inferred="true"} ! megakaryocyte-erythroid progenitor cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000050 ! megakaryocyte-erythroid progenitor cell -intersection_of: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA -intersection_of: lacks_plasma_membrane_part PR:000001865 ! interleukin-3 receptor class 2 alpha chain +intersection_of: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA +intersection_of: CL:4030046 PR:000001865 ! lacks_plasma_membrane_part interleukin-3 receptor class 2 alpha chain intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule intersection_of: RO:0002104 PR:000001408 ! has plasma membrane part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +relationship: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA +relationship: CL:4030046 PR:000001865 ! lacks_plasma_membrane_part interleukin-3 receptor class 2 alpha chain relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA -relationship: lacks_plasma_membrane_part PR:000001865 ! interleukin-3 receptor class 2 alpha chain relationship: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule relationship: RO:0002104 PR:000001408 ! has plasma membrane part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 creation_date: 2010-01-13T03:43:10Z @@ -25130,19 +14184,19 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000050 {is_inferred="true"} ! megakaryocyte-erythroid progenitor cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000050 ! megakaryocyte-erythroid progenitor cell -intersection_of: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule -intersection_of: lacks_plasma_membrane_part PR:000001479 ! low affinity immunoglobulin gamma Fc region receptor II -intersection_of: lacks_plasma_membrane_part PR:000001843 ! Thy-1 membrane glycoprotein -intersection_of: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -intersection_of: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 +intersection_of: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule +intersection_of: CL:4030046 PR:000001479 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor II +intersection_of: CL:4030046 PR:000001843 ! lacks_plasma_membrane_part Thy-1 membrane glycoprotein +intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +intersection_of: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 intersection_of: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor intersection_of: RO:0015016 GO:0033001 ! has low plasma membrane amount Fc-gamma receptor III complex +relationship: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule +relationship: CL:4030046 PR:000001479 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor II +relationship: CL:4030046 PR:000001843 ! lacks_plasma_membrane_part Thy-1 membrane glycoprotein +relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +relationship: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule -relationship: lacks_plasma_membrane_part PR:000001479 ! low affinity immunoglobulin gamma Fc region receptor II -relationship: lacks_plasma_membrane_part PR:000001843 ! Thy-1 membrane glycoprotein -relationship: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -relationship: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 relationship: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor relationship: RO:0015016 GO:0033001 ! has low plasma membrane amount Fc-gamma receptor III complex creation_date: 2010-01-13T03:43:12Z @@ -25154,13 +14208,13 @@ def: "A lineage marker-negative, CD34-positive, IL5r-alpha-positive, and Sca1-ne comment: Markers are found on mouse cells. is_a: CL:0000611 {is_inferred="true"} ! eosinophil progenitor cell intersection_of: CL:0000611 ! eosinophil progenitor cell -intersection_of: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 +intersection_of: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule intersection_of: RO:0002104 PR:000001867 ! has plasma membrane part interleukin-5 receptor subunit alpha intersection_of: RO:0015016 PR:000002065 ! has low plasma membrane amount mast/stem cell growth factor receptor +relationship: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002002 ! Kit-positive granulocyte monocyte progenitor -relationship: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 relationship: RO:0015016 PR:000002065 ! has low plasma membrane amount mast/stem cell growth factor receptor creation_date: 2010-01-14T03:25:15Z @@ -25203,37 +14257,38 @@ def: "A lin-negative, MHC-II-negative, CD11c-positive, FLT3-positive cell with i is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000763 ! myeloid cell is_a: CL:0002031 {is_inferred="true"} ! hematopoietic lineage restricted progenitor cell +is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0002031 ! hematopoietic lineage restricted progenitor cell -intersection_of: lacks_plasma_membrane_part GO:0042613 ! MHC class II protein complex -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -intersection_of: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -intersection_of: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -intersection_of: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) +intersection_of: CL:4030046 GO:0042613 ! lacks_plasma_membrane_part MHC class II protein complex +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: RO:0002104 PR:000001013 ! has plasma membrane part integrin alpha-X intersection_of: RO:0002104 PR:000001968 ! has plasma membrane part tyrosine-protein phosphatase non-receptor type substrate 1 intersection_of: RO:0002104 PR:000002001 ! has plasma membrane part receptor-type tyrosine-protein kinase FLT3 +relationship: CL:4030046 GO:0042613 ! lacks_plasma_membrane_part MHC class II protein complex +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule +relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G +relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: develops_from CL:0001029 ! common dendritic progenitor -relationship: lacks_plasma_membrane_part GO:0042613 ! MHC class II protein complex -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -relationship: lacks_plasma_membrane_part PR:000001083 ! CD2 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -relationship: lacks_plasma_membrane_part PR:000001889 ! CD14 molecule -relationship: lacks_plasma_membrane_part PR:000002978 ! lymphocyte antigen 6G -relationship: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) relationship: RO:0002104 PR:000001013 ! has plasma membrane part integrin alpha-X relationship: RO:0002104 PR:000001968 ! has plasma membrane part tyrosine-protein phosphatase non-receptor type substrate 1 relationship: RO:0002104 PR:000002001 ! has plasma membrane part receptor-type tyrosine-protein kinase FLT3 @@ -25268,15 +14323,15 @@ def: "A proerythoblast that is Kit-low, Lyg76-positive, and CD71-positive." [GOC comment: Markers are associated with mouse cells. is_a: CL:0000547 {is_inferred="true"} ! proerythroblast intersection_of: CL:0000547 ! proerythroblast -intersection_of: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -intersection_of: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 +intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +intersection_of: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 intersection_of: RO:0002104 PR:000002981 ! has plasma membrane part lymphocyte antigen 76 (mouse) intersection_of: RO:0015015 PR:000001945 ! has high plasma membrane amount transferrin receptor protein 1 intersection_of: RO:0015016 PR:000002065 ! has low plasma membrane amount mast/stem cell growth factor receptor +relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +relationship: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002000 ! Kit-positive erythroid progenitor cell -relationship: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -relationship: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 relationship: RO:0002104 PR:000002981 ! has plasma membrane part lymphocyte antigen 76 (mouse) relationship: RO:0015015 PR:000001945 ! has high plasma membrane amount transferrin receptor protein 1 relationship: RO:0015016 PR:000002065 ! has low plasma membrane amount mast/stem cell growth factor receptor @@ -25289,11 +14344,11 @@ def: "A basophilic erythroblast that is GlyA-positive." [GOC:ak, GOC:tfm, PMID:1 comment: Markers are associated with human cells. is_a: CL:0000549 {is_inferred="true"} ! basophilic erythroblast intersection_of: CL:0000549 ! basophilic erythroblast -intersection_of: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule +intersection_of: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule intersection_of: RO:0002104 PR:000001460 ! has plasma membrane part glycophorin-A +relationship: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002004 ! CD34-negative, GlyA-negative proerythroblast -relationship: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule relationship: RO:0002104 PR:000001460 ! has plasma membrane part glycophorin-A creation_date: 2010-04-26T10:41:15Z @@ -25304,15 +14359,15 @@ def: "A basophilic erythroblast that is Lyg 76-high and is Kit-negative." [GOC:a comment: Cell surface markers are associated with mouse cells. is_a: CL:0000549 {is_inferred="true"} ! basophilic erythroblast intersection_of: CL:0000549 ! basophilic erythroblast -intersection_of: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -intersection_of: lacks_plasma_membrane_part PR:000002065 ! mast/stem cell growth factor receptor -intersection_of: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 +intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +intersection_of: CL:4030046 PR:000002065 ! lacks_plasma_membrane_part mast/stem cell growth factor receptor +intersection_of: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 intersection_of: RO:0015015 PR:000002981 ! has high plasma membrane amount lymphocyte antigen 76 (mouse) +relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +relationship: CL:4030046 PR:000002065 ! lacks_plasma_membrane_part mast/stem cell growth factor receptor +relationship: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002012 ! Kit-low proerythroblast -relationship: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -relationship: lacks_plasma_membrane_part PR:000002065 ! mast/stem cell growth factor receptor -relationship: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 relationship: RO:0015015 PR:000002981 ! has high plasma membrane amount lymphocyte antigen 76 (mouse) creation_date: 2010-04-26T10:41:22Z @@ -25323,15 +14378,15 @@ def: "A polychromatophilic erythroblast that is Lyg 76-high and is Kit-negative. synonym: "late basophilic and polychromatophilic erythroblast" BROAD [] is_a: CL:0000550 {is_inferred="true"} ! polychromatophilic erythroblast intersection_of: CL:0000550 ! polychromatophilic erythroblast -intersection_of: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -intersection_of: lacks_plasma_membrane_part PR:000002065 ! mast/stem cell growth factor receptor -intersection_of: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 +intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +intersection_of: CL:4030046 PR:000002065 ! lacks_plasma_membrane_part mast/stem cell growth factor receptor +intersection_of: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 intersection_of: RO:0015015 PR:000002981 ! has high plasma membrane amount lymphocyte antigen 76 (mouse) +relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +relationship: CL:4030046 PR:000002065 ! lacks_plasma_membrane_part mast/stem cell growth factor receptor +relationship: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002014 ! Kit-negative, Ly-76 high basophilic erythroblast -relationship: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -relationship: lacks_plasma_membrane_part PR:000002065 ! mast/stem cell growth factor receptor -relationship: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 relationship: RO:0015015 PR:000002981 ! has high plasma membrane amount lymphocyte antigen 76 (mouse) creation_date: 2010-04-26T10:53:11Z @@ -25359,16 +14414,16 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000552 {is_inferred="true"} ! orthochromatic erythroblast is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000552 ! orthochromatic erythroblast -intersection_of: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -intersection_of: lacks_plasma_membrane_part PR:000002065 ! mast/stem cell growth factor receptor -intersection_of: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 +intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +intersection_of: CL:4030046 PR:000002065 ! lacks_plasma_membrane_part mast/stem cell growth factor receptor +intersection_of: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 intersection_of: RO:0015015 PR:000002981 ! has high plasma membrane amount lymphocyte antigen 76 (mouse) intersection_of: RO:0015016 PR:000001945 ! has low plasma membrane amount transferrin receptor protein 1 +relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +relationship: CL:4030046 PR:000002065 ! lacks_plasma_membrane_part mast/stem cell growth factor receptor +relationship: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002015 ! Kit-negative, Ly-76 high polychromatophilic erythroblast -relationship: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -relationship: lacks_plasma_membrane_part PR:000002065 ! mast/stem cell growth factor receptor -relationship: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 relationship: RO:0015015 PR:000002981 ! has high plasma membrane amount lymphocyte antigen 76 (mouse) relationship: RO:0015016 PR:000001945 ! has low plasma membrane amount transferrin receptor protein 1 creation_date: 2010-04-26T11:04:15Z @@ -25382,11 +14437,11 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000552 {is_inferred="true"} ! orthochromatic erythroblast is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000552 ! orthochromatic erythroblast -intersection_of: lacks_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 +intersection_of: CL:4030046 PR:000001945 ! lacks_plasma_membrane_part transferrin receptor protein 1 intersection_of: RO:0002104 PR:000001460 ! has plasma membrane part glycophorin-A +relationship: CL:4030046 PR:000001945 ! lacks_plasma_membrane_part transferrin receptor protein 1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002016 ! CD71-low, GlyA-positive polychromatic erythroblast -relationship: lacks_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 relationship: RO:0002104 PR:000001460 ! has plasma membrane part glycophorin-A creation_date: 2010-04-26T11:04:21Z @@ -25474,18 +14529,18 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000553 {is_inferred="true"} ! megakaryocyte progenitor cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000553 ! megakaryocyte progenitor cell -intersection_of: lacks_plasma_membrane_part PR:000001833 ! SLAM family member 1 -intersection_of: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -intersection_of: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 +intersection_of: CL:4030046 PR:000001833 ! lacks_plasma_membrane_part SLAM family member 1 +intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +intersection_of: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 intersection_of: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor intersection_of: RO:0002104 PR:000005178 ! has plasma membrane part CD9 molecule intersection_of: RO:0015016 PR:000001479 ! has low plasma membrane amount low affinity immunoglobulin gamma Fc region receptor II intersection_of: RO:0015016 PR:000001483 ! has low plasma membrane amount low affinity immunoglobulin gamma Fc region receptor III +relationship: CL:4030046 PR:000001833 ! lacks_plasma_membrane_part SLAM family member 1 +relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha +relationship: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002006 ! Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell -relationship: lacks_plasma_membrane_part PR:000001833 ! SLAM family member 1 -relationship: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha -relationship: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 relationship: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor relationship: RO:0002104 PR:000005178 ! has plasma membrane part CD9 molecule relationship: RO:0015016 PR:000001479 ! has low plasma membrane amount low affinity immunoglobulin gamma Fc region receptor II @@ -25501,12 +14556,12 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000553 {is_inferred="true"} ! megakaryocyte progenitor cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000553 ! megakaryocyte progenitor cell -intersection_of: lacks_plasma_membrane_part PR:000001907 ! platelet glycoprotein Ib alpha chain +intersection_of: CL:4030046 PR:000001907 ! lacks_plasma_membrane_part platelet glycoprotein Ib alpha chain intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule intersection_of: RO:0002104 PR:000009127 ! has plasma membrane part integrin alpha-IIb +relationship: CL:4030046 PR:000001907 ! lacks_plasma_membrane_part platelet glycoprotein Ib alpha chain relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002005 ! CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell -relationship: lacks_plasma_membrane_part PR:000001907 ! platelet glycoprotein Ib alpha chain relationship: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule relationship: RO:0002104 PR:000009127 ! has plasma membrane part integrin alpha-IIb creation_date: 2010-04-26T03:52:47Z @@ -25518,13 +14573,14 @@ def: "A megakaryocyte progenitor cell that is CD34-negative, CD41-positive and C comment: Markers are commonly associated with human cells. is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000556 {is_inferred="true"} ! megakaryocyte +is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000556 ! megakaryocyte -intersection_of: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule +intersection_of: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule intersection_of: RO:0002104 PR:000001907 ! has plasma membrane part platelet glycoprotein Ib alpha chain intersection_of: RO:0002104 PR:000009127 ! has plasma membrane part integrin alpha-IIb +relationship: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002023 ! CD34-positive, CD41-positive, CD42-positive megakaryocyte progenitor cell -relationship: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule relationship: RO:0002104 PR:000001907 ! has plasma membrane part platelet glycoprotein Ib alpha chain relationship: RO:0002104 PR:000009127 ! has plasma membrane part integrin alpha-IIb creation_date: 2010-04-26T03:59:22Z @@ -25536,6 +14592,7 @@ def: "A megakaryocyte cell with is CD9-positive and CD41-positive." [GOC:tfm] comment: Markers are commonly associated with mouse cells. is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000556 {is_inferred="true"} ! megakaryocyte +is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000556 ! megakaryocyte intersection_of: RO:0002104 PR:000005178 ! has plasma membrane part CD9 molecule intersection_of: RO:0002104 PR:000009127 ! has plasma membrane part integrin alpha-IIb @@ -25558,21 +14615,21 @@ is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000839 ! myeloid lineage restricted progenitor cell intersection_of: capable_of GO:0030221 ! basophil differentiation intersection_of: capable_of GO:0060374 ! mast cell differentiation +intersection_of: CL:4030046 PR:000007431 ! lacks_plasma_membrane_part high affinity immunoglobulin epsilon receptor subunit alpha +intersection_of: CL:4030046 PR:000016401 ! lacks_plasma_membrane_part transmembrane emp24 domain-containing protein 1 intersection_of: has_part PR:000005307 ! CCAAT/enhancer-binding protein alpha intersection_of: has_part PR:000007857 ! erythroid transcription factor intersection_of: has_part PR:000007858 ! endothelial transcription factor GATA-2 -intersection_of: lacks_plasma_membrane_part PR:000007431 ! high affinity immunoglobulin epsilon receptor subunit alpha -intersection_of: lacks_plasma_membrane_part PR:000016401 ! transmembrane emp24 domain-containing protein 1 intersection_of: RO:0002104 PR:000001867 ! has plasma membrane part interleukin-5 receptor subunit alpha relationship: capable_of GO:0030221 ! basophil differentiation relationship: capable_of GO:0060374 ! mast cell differentiation +relationship: CL:4030046 PR:000007431 ! lacks_plasma_membrane_part high affinity immunoglobulin epsilon receptor subunit alpha +relationship: CL:4030046 PR:000016401 ! lacks_plasma_membrane_part transmembrane emp24 domain-containing protein 1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000557 ! granulocyte monocyte progenitor cell relationship: has_part PR:000005307 ! CCAAT/enhancer-binding protein alpha relationship: has_part PR:000007857 ! erythroid transcription factor relationship: has_part PR:000007858 ! endothelial transcription factor GATA-2 -relationship: lacks_plasma_membrane_part PR:000007431 ! high affinity immunoglobulin epsilon receptor subunit alpha -relationship: lacks_plasma_membrane_part PR:000016401 ! transmembrane emp24 domain-containing protein 1 relationship: RO:0002104 PR:000001867 ! has plasma membrane part interleukin-5 receptor subunit alpha creation_date: 2010-04-27T12:46:33Z @@ -25582,7 +14639,7 @@ name: Fc-epsilon RIalpha-low mast cell progenitor def: "A lineage-negative, Kit-positive, CD45-positive mast cell progenitor that is Fc-epsilon RIalpha-low." [GOC:tfm, PMCID:PMC1312421] is_a: CL:0000831 {is_inferred="true"} ! mast cell progenitor intersection_of: CL:0000831 ! mast cell progenitor -intersection_of: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 +intersection_of: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 intersection_of: RO:0002104 PR:000001006 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C intersection_of: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor intersection_of: RO:0002104 PR:000009143 ! has plasma membrane part integrin beta-7 @@ -25601,13 +14658,13 @@ def: "A lineage negative, Sca1-negative basophil progenitor cell that is Fc epsi comment: Markers are associated with mouse cells. is_a: CL:0000613 {is_inferred="true"} ! basophil progenitor cell intersection_of: CL:0000613 ! basophil progenitor cell -intersection_of: lacks_plasma_membrane_part PR:000002065 ! mast/stem cell growth factor receptor -intersection_of: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 +intersection_of: CL:4030046 PR:000002065 ! lacks_plasma_membrane_part mast/stem cell growth factor receptor +intersection_of: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule intersection_of: RO:0015015 PR:000007431 ! has high plasma membrane amount high affinity immunoglobulin epsilon receptor subunit alpha +relationship: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002044 ! Kit-positive, integrin beta7-high basophil mast progenitor cell -relationship: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 relationship: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule creation_date: 2010-04-27T01:22:32Z @@ -25648,12 +14705,12 @@ synonym: "ST stem cell" EXACT [] synonym: "ST-HSC" EXACT [] is_a: CL:0001008 {is_inferred="true"} ! Kit and Sca1-positive hematopoietic stem cell intersection_of: CL:0001008 ! Kit and Sca1-positive hematopoietic stem cell -intersection_of: lacks_plasma_membrane_part PR:000002001 ! receptor-type tyrosine-protein kinase FLT3 +intersection_of: CL:4030046 PR:000002001 ! lacks_plasma_membrane_part receptor-type tyrosine-protein kinase FLT3 intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule intersection_of: RO:0002104 PR:000001833 ! has plasma membrane part SLAM family member 1 +relationship: CL:4030046 PR:000002001 ! lacks_plasma_membrane_part receptor-type tyrosine-protein kinase FLT3 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002034 ! long term hematopoietic stem cell -relationship: lacks_plasma_membrane_part PR:000002001 ! receptor-type tyrosine-protein kinase FLT3 relationship: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule creation_date: 2010-01-08T09:19:25Z @@ -25666,13 +14723,13 @@ synonym: "LT stem cell" EXACT [] synonym: "LT-HSC" EXACT [] is_a: CL:0001008 {is_inferred="true"} ! Kit and Sca1-positive hematopoietic stem cell intersection_of: CL:0001008 ! Kit and Sca1-positive hematopoietic stem cell -intersection_of: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule -intersection_of: lacks_plasma_membrane_part PR:000002001 ! receptor-type tyrosine-protein kinase FLT3 +intersection_of: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule +intersection_of: CL:4030046 PR:000002001 ! lacks_plasma_membrane_part receptor-type tyrosine-protein kinase FLT3 intersection_of: RO:0002104 PR:000001833 ! has plasma membrane part SLAM family member 1 intersection_of: RO:0015016 PR:000001843 ! has low plasma membrane amount Thy-1 membrane glycoprotein +relationship: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule +relationship: CL:4030046 PR:000002001 ! lacks_plasma_membrane_part receptor-type tyrosine-protein kinase FLT3 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule -relationship: lacks_plasma_membrane_part PR:000002001 ! receptor-type tyrosine-protein kinase FLT3 relationship: RO:0015016 PR:000001843 ! has low plasma membrane amount Thy-1 membrane glycoprotein creation_date: 2010-01-08T09:19:28Z @@ -25683,14 +14740,14 @@ def: "A hematopoietic progenitor that has restricted self-renewal capability. Ce comment: Markers are associated with mouse cells. is_a: CL:0000837 {is_inferred="true"} ! hematopoietic multipotent progenitor cell intersection_of: CL:0000837 ! hematopoietic multipotent progenitor cell -intersection_of: lacks_plasma_membrane_part PR:000001833 ! SLAM family member 1 -intersection_of: lacks_plasma_membrane_part PR:000002001 ! receptor-type tyrosine-protein kinase FLT3 +intersection_of: CL:4030046 PR:000001833 ! lacks_plasma_membrane_part SLAM family member 1 +intersection_of: CL:4030046 PR:000002001 ! lacks_plasma_membrane_part receptor-type tyrosine-protein kinase FLT3 intersection_of: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor intersection_of: RO:0002104 PR:000002979 ! has plasma membrane part lymphocyte antigen 6A-2/6E-1 +relationship: CL:4030046 PR:000001833 ! lacks_plasma_membrane_part SLAM family member 1 +relationship: CL:4030046 PR:000002001 ! lacks_plasma_membrane_part receptor-type tyrosine-protein kinase FLT3 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002036 ! Slamf1-positive multipotent progenitor cell -relationship: lacks_plasma_membrane_part PR:000001833 ! SLAM family member 1 -relationship: lacks_plasma_membrane_part PR:000002001 ! receptor-type tyrosine-protein kinase FLT3 relationship: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor relationship: RO:0002104 PR:000002979 ! has plasma membrane part lymphocyte antigen 6A-2/6E-1 creation_date: 2010-01-08T11:16:33Z @@ -25747,16 +14804,16 @@ is_a: CL:0000492 {is_inferred="true"} ! CD4-positive helper T cell intersection_of: CL:0000492 ! CD4-positive helper T cell intersection_of: capable_of GO:0045830 ! positive regulation of isotype switching intersection_of: capable_of GO:0051024 +intersection_of: CL:4030046 PR:000001203 ! lacks_plasma_membrane_part C-C chemokine receptor type 7 intersection_of: has_part PR:000003450 ! B-cell lymphoma 6 protein -intersection_of: lacks_plasma_membrane_part PR:000001203 ! C-C chemokine receptor type 7 intersection_of: RO:0002104 PR:000001209 ! has plasma membrane part C-X-C chemokine receptor type 5 intersection_of: RO:0002104 PR:000001860 ! has plasma membrane part inducible T-cell costimulator intersection_of: RO:0002104 PR:000001919 ! has plasma membrane part programmed cell death protein 1 relationship: capable_of GO:0045830 ! positive regulation of isotype switching relationship: capable_of GO:0051024 +relationship: CL:4030046 PR:000001203 ! lacks_plasma_membrane_part C-C chemokine receptor type 7 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: has_part PR:000003450 ! B-cell lymphoma 6 protein -relationship: lacks_plasma_membrane_part PR:000001203 ! C-C chemokine receptor type 7 relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001209 ! has plasma membrane part C-X-C chemokine receptor type 5 relationship: RO:0002104 PR:000001860 ! has plasma membrane part inducible T-cell costimulator @@ -25769,14 +14826,14 @@ name: immature NK T cell stage I def: "A CD24-high, CD4-low, CD8-low, CD44-negative, NK1.1-negative NK T cell." [GOC:tfm, PMID:17589542] is_a: CL:0000914 {is_inferred="true"} ! immature NK T cell intersection_of: CL:0000914 ! immature NK T cell -intersection_of: lacks_plasma_membrane_part PR:000001307 ! CD44 molecule -intersection_of: lacks_plasma_membrane_part PR:000001874 ! KLRB1-like protein +intersection_of: CL:4030046 PR:000001307 ! lacks_plasma_membrane_part CD44 molecule +intersection_of: CL:4030046 PR:000001874 ! lacks_plasma_membrane_part KLRB1-like protein intersection_of: RO:0015015 PR:000001932 ! has high plasma membrane amount signal transducer CD24 intersection_of: RO:0015016 PR:000001004 ! has low plasma membrane amount CD4 molecule intersection_of: RO:0015016 PR:000025402 ! has low plasma membrane amount T cell receptor co-receptor CD8 +relationship: CL:4030046 PR:000001307 ! lacks_plasma_membrane_part CD44 molecule +relationship: CL:4030046 PR:000001874 ! lacks_plasma_membrane_part KLRB1-like protein relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001307 ! CD44 molecule -relationship: lacks_plasma_membrane_part PR:000001874 ! KLRB1-like protein relationship: RO:0015015 PR:000001932 ! has high plasma membrane amount signal transducer CD24 relationship: RO:0015016 PR:000001004 ! has low plasma membrane amount CD4 molecule relationship: RO:0015016 PR:000025402 ! has low plasma membrane amount T cell receptor co-receptor CD8 @@ -25790,13 +14847,13 @@ comment: NKT.44-NK1.1-.Th was assigned as an exact synonym based on sorting stra synonym: "NKT.44-NK1.1-.Th" EXACT [] is_a: CL:0000914 {is_inferred="true"} ! immature NK T cell intersection_of: CL:0000914 ! immature NK T cell -intersection_of: lacks_plasma_membrane_part PR:000001307 ! CD44 molecule -intersection_of: lacks_plasma_membrane_part PR:000001874 ! KLRB1-like protein +intersection_of: CL:4030046 PR:000001307 ! lacks_plasma_membrane_part CD44 molecule +intersection_of: CL:4030046 PR:000001874 ! lacks_plasma_membrane_part KLRB1-like protein intersection_of: RO:0015016 PR:000001932 ! has low plasma membrane amount signal transducer CD24 +relationship: CL:4030046 PR:000001307 ! lacks_plasma_membrane_part CD44 molecule +relationship: CL:4030046 PR:000001874 ! lacks_plasma_membrane_part KLRB1-like protein relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002039 ! immature NK T cell stage I -relationship: lacks_plasma_membrane_part PR:000001307 ! CD44 molecule -relationship: lacks_plasma_membrane_part PR:000001874 ! KLRB1-like protein relationship: RO:0015016 PR:000001932 ! has low plasma membrane amount signal transducer CD24 creation_date: 2009-10-29T04:13:43Z @@ -25807,13 +14864,13 @@ def: "A CD24-low, CD44-positive, DX5-low, NK1.1-negative NK T cell." [PMID:17589 synonym: "NKT.44+.NK1.1-.Th" BROAD [] is_a: CL:0000914 {is_inferred="true"} ! immature NK T cell intersection_of: CL:0000914 ! immature NK T cell -intersection_of: lacks_plasma_membrane_part PR:000001874 ! KLRB1-like protein +intersection_of: CL:4030046 PR:000001874 ! lacks_plasma_membrane_part KLRB1-like protein intersection_of: RO:0002104 PR:000001307 ! has plasma membrane part CD44 molecule intersection_of: RO:0015016 PR:000001008 ! has low plasma membrane amount integrin alpha-2 intersection_of: RO:0015016 PR:000001932 ! has low plasma membrane amount signal transducer CD24 +relationship: CL:4030046 PR:000001874 ! lacks_plasma_membrane_part KLRB1-like protein relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002040 ! immature NK T cell stage II -relationship: lacks_plasma_membrane_part PR:000001874 ! KLRB1-like protein relationship: RO:0002104 PR:000001307 ! has plasma membrane part CD44 molecule relationship: RO:0015016 PR:000001008 ! has low plasma membrane amount integrin alpha-2 relationship: RO:0015016 PR:000001932 ! has low plasma membrane amount signal transducer CD24 @@ -25827,13 +14884,13 @@ subset: human_reference_atlas synonym: "NKT.44+.NK1.1-.Th" BROAD [] is_a: CL:0000914 {is_inferred="true"} ! immature NK T cell intersection_of: CL:0000914 ! immature NK T cell -intersection_of: lacks_plasma_membrane_part PR:000001874 ! KLRB1-like protein +intersection_of: CL:4030046 PR:000001874 ! lacks_plasma_membrane_part KLRB1-like protein intersection_of: RO:0002104 PR:000001307 ! has plasma membrane part CD44 molecule intersection_of: RO:0015015 PR:000001008 ! has high plasma membrane amount integrin alpha-2 intersection_of: RO:0015016 PR:000001932 ! has low plasma membrane amount signal transducer CD24 +relationship: CL:4030046 PR:000001874 ! lacks_plasma_membrane_part KLRB1-like protein relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002041 ! immature NK T cell stage III -relationship: lacks_plasma_membrane_part PR:000001874 ! KLRB1-like protein relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001307 ! has plasma membrane part CD44 molecule relationship: RO:0015015 PR:000001008 ! has high plasma membrane amount integrin alpha-2 @@ -25847,15 +14904,15 @@ def: "A hematopoietic multipotent progenitor cell that is CD34-positive, CD38-ne comment: Cell markers are associated with human hematopoietic multipotent progenitor cells. is_a: CL:0000837 {is_inferred="true"} ! hematopoietic multipotent progenitor cell intersection_of: CL:0000837 ! hematopoietic multipotent progenitor cell -intersection_of: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA -intersection_of: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 -intersection_of: lacks_plasma_membrane_part PR:000001843 ! Thy-1 membrane glycoprotein +intersection_of: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA +intersection_of: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +intersection_of: CL:4030046 PR:000001843 ! lacks_plasma_membrane_part Thy-1 membrane glycoprotein intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule +relationship: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA +relationship: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +relationship: CL:4030046 PR:000001843 ! lacks_plasma_membrane_part Thy-1 membrane glycoprotein relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0001024 ! CD34-positive, CD38-negative hematopoietic stem cell -relationship: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA -relationship: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 -relationship: lacks_plasma_membrane_part PR:000001843 ! Thy-1 membrane glycoprotein creation_date: 2010-01-12T11:14:15Z [Term] @@ -25865,14 +14922,14 @@ def: "A basophil mast progenitor cell that is Beta-7 integrin-high, Kit-positive comment: Markers are associated with mouse cells. is_a: CL:0002028 {is_inferred="true"} ! basophil mast progenitor cell intersection_of: CL:0002028 ! basophil mast progenitor cell -intersection_of: lacks_plasma_membrane_part PR:000002065 ! mast/stem cell growth factor receptor -intersection_of: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 +intersection_of: CL:4030046 PR:000002065 ! lacks_plasma_membrane_part mast/stem cell growth factor receptor +intersection_of: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 intersection_of: RO:0002104 PR:000001479 ! has plasma membrane part low affinity immunoglobulin gamma Fc region receptor II intersection_of: RO:0002104 PR:000001483 ! has plasma membrane part low affinity immunoglobulin gamma Fc region receptor III intersection_of: RO:0015015 PR:000009143 ! has high plasma membrane amount integrin beta-7 +relationship: CL:4030046 PR:000002065 ! lacks_plasma_membrane_part mast/stem cell growth factor receptor +relationship: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000002065 ! mast/stem cell growth factor receptor -relationship: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 relationship: RO:0002104 PR:000001479 ! has plasma membrane part low affinity immunoglobulin gamma Fc region receptor II relationship: RO:0002104 PR:000001483 ! has plasma membrane part low affinity immunoglobulin gamma Fc region receptor III relationship: RO:0015015 PR:000009143 ! has high plasma membrane amount integrin beta-7 @@ -25888,16 +14945,16 @@ synonym: "pre pro B cell" RELATED [] is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000826 {is_inferred="true"} ! pro-B cell intersection_of: CL:0000826 ! pro-B cell -intersection_of: lacks_plasma_membrane_part PR:000002039 ! glutamyl aminopeptidase -intersection_of: lacks_plasma_membrane_part PR:000002980 ! lymphocyte antigen 6C2 +intersection_of: CL:4030046 PR:000002039 ! lacks_plasma_membrane_part glutamyl aminopeptidase +intersection_of: CL:4030046 PR:000002980 ! lacks_plasma_membrane_part lymphocyte antigen 6C2 intersection_of: RO:0002104 PR:000001015 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RA intersection_of: RO:0002104 PR:000001879 ! has plasma membrane part leukosialin intersection_of: RO:0002104 PR:000002037 ! has plasma membrane part complement component C1q receptor intersection_of: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor intersection_of: RO:0015016 PR:000001932 ! has low plasma membrane amount signal transducer CD24 +relationship: CL:4030046 PR:000002039 ! lacks_plasma_membrane_part glutamyl aminopeptidase +relationship: CL:4030046 PR:000002980 ! lacks_plasma_membrane_part lymphocyte antigen 6C2 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000002039 ! glutamyl aminopeptidase -relationship: lacks_plasma_membrane_part PR:000002980 ! lymphocyte antigen 6C2 relationship: RO:0002104 PR:000001015 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RA relationship: RO:0002104 PR:000001879 ! has plasma membrane part leukosialin relationship: RO:0002104 PR:000002037 ! has plasma membrane part complement component C1q receptor @@ -25913,19 +14970,19 @@ comment: Markers are commonly associated with human cells. These cells are also is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000826 {is_inferred="true"} ! pro-B cell intersection_of: CL:0000826 ! pro-B cell -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -intersection_of: lacks_plasma_membrane_part PR:000001338 ! complement receptor type 2 +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030046 PR:000001338 ! lacks_plasma_membrane_part complement receptor type 2 intersection_of: participates_in GO:0071707 ! immunoglobulin heavy chain V-D-J recombination intersection_of: RO:0002104 GO:0035369 ! has plasma membrane part pre-B cell receptor complex intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule intersection_of: RO:0002104 PR:000001288 ! has plasma membrane part B-cell receptor CD22 intersection_of: RO:0002104 PR:000001408 ! has plasma membrane part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 intersection_of: RO:0015016 PR:000001898 ! has low plasma membrane amount neprilysin +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030046 PR:000001338 ! lacks_plasma_membrane_part complement receptor type 2 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 -relationship: lacks_plasma_membrane_part PR:000001338 ! complement receptor type 2 relationship: participates_in GO:0071707 ! immunoglobulin heavy chain V-D-J recombination relationship: RO:0002104 GO:0035369 ! has plasma membrane part pre-B cell receptor complex relationship: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule @@ -25943,12 +15000,12 @@ synonym: "Fr. B" BROAD [] synonym: "Fraction B" BROAD [] is_a: CL:0002400 {is_inferred="true"} ! fraction B/C precursor B cell intersection_of: CL:0002400 ! fraction B/C precursor B cell -intersection_of: lacks_plasma_membrane_part PR:000002039 ! glutamyl aminopeptidase +intersection_of: CL:4030046 PR:000002039 ! lacks_plasma_membrane_part glutamyl aminopeptidase intersection_of: RO:0002104 PR:000001014 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RABC intersection_of: RO:0002104 PR:000001932 ! has plasma membrane part signal transducer CD24 +relationship: CL:4030046 PR:000002039 ! lacks_plasma_membrane_part glutamyl aminopeptidase relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002045 ! fraction A pre-pro B cell -relationship: lacks_plasma_membrane_part PR:000002039 ! glutamyl aminopeptidase relationship: RO:0002104 PR:000001014 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RABC creation_date: 2010-04-28T11:56:21Z @@ -25978,7 +15035,7 @@ def: "A precursor B cell that is CD45R-positive, CD43-positive, CD24-positive, a synonym: "Fraction C" RELATED [] is_a: CL:0002400 {is_inferred="true"} ! fraction B/C precursor B cell intersection_of: CL:0002400 ! fraction B/C precursor B cell -intersection_of: has_not_completed GO:0071707 ! immunoglobulin heavy chain V-D-J recombination +intersection_of: CL:4030044 GO:0071707 ! has_not_completed immunoglobulin heavy chain V-D-J recombination intersection_of: has_part PR:000001858 ! immunoglobulin iota chain intersection_of: has_part PR:000001859 ! immunoglobulin lambda-like polypeptide 1 intersection_of: RO:0002104 PR:000001014 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RABC @@ -25986,9 +15043,9 @@ intersection_of: RO:0002104 PR:000001932 ! has plasma membrane part signal trans intersection_of: RO:0002104 PR:000002039 ! has plasma membrane part glutamyl aminopeptidase intersection_of: RO:0002104 PR:000003457 ! has plasma membrane part V(D)J recombination-activating protein 1 intersection_of: RO:0002104 PR:000003460 ! has plasma membrane part V(D)J recombination-activating protein 2 +relationship: CL:4030044 GO:0071707 ! has_not_completed immunoglobulin heavy chain V-D-J recombination relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002047 ! fraction B precursor B cell -relationship: has_not_completed GO:0071707 ! immunoglobulin heavy chain V-D-J recombination relationship: has_part PR:000001858 ! immunoglobulin iota chain relationship: has_part PR:000001859 ! immunoglobulin lambda-like polypeptide 1 relationship: RO:0002104 PR:000001014 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RABC @@ -26046,8 +15103,8 @@ synonym: "Fr. D" BROAD [] synonym: "fraction D pre-B cell" EXACT [GOC:tfm] is_a: CL:0002400 ! fraction B/C precursor B cell intersection_of: CL:0000817 ! precursor B cell -intersection_of: has_not_completed GO:0071708 ! immunoglobulin light chain V-J recombination -intersection_of: lacks_plasma_membrane_part GO:0035369 ! pre-B cell receptor complex +intersection_of: CL:4030044 GO:0071708 ! has_not_completed immunoglobulin light chain V-J recombination +intersection_of: CL:4030046 GO:0035369 ! lacks_plasma_membrane_part pre-B cell receptor complex intersection_of: RO:0002104 PR:000001002 ! has plasma membrane part CD19 molecule intersection_of: RO:0002104 PR:000001014 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RABC intersection_of: RO:0002104 PR:000001380 ! has plasma membrane part interleukin-2 receptor subunit alpha @@ -26055,10 +15112,10 @@ intersection_of: RO:0002104 PR:000001932 ! has plasma membrane part signal trans intersection_of: RO:0002104 PR:000002037 ! has plasma membrane part complement component C1q receptor intersection_of: RO:0002104 PR:000002039 ! has plasma membrane part glutamyl aminopeptidase intersection_of: RO:0015016 PR:000001879 ! has low plasma membrane amount leukosialin +relationship: CL:4030044 GO:0071708 ! has_not_completed immunoglobulin light chain V-J recombination +relationship: CL:4030046 GO:0035369 ! lacks_plasma_membrane_part pre-B cell receptor complex relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002050 ! fraction C' precursor B cell -relationship: has_not_completed GO:0071708 ! immunoglobulin light chain V-J recombination -relationship: lacks_plasma_membrane_part GO:0035369 ! pre-B cell receptor complex relationship: RO:0002104 PR:000001014 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RABC relationship: RO:0002104 PR:000001380 ! has plasma membrane part interleukin-2 receptor subunit alpha relationship: RO:0002104 PR:000002039 ! has plasma membrane part glutamyl aminopeptidase @@ -26088,16 +15145,16 @@ def: "An immature B cell that is IgM-positive, CD45R-positive, CD43-low, CD25-ne comment: Markers associated with mouse cells. These cells are also reportedly sIgD-negative. is_a: CL:0000816 {is_inferred="true"} ! immature B cell intersection_of: CL:0000816 ! immature B cell -intersection_of: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha -intersection_of: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha +intersection_of: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha +intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha intersection_of: RO:0002104 PR:000001002 ! has plasma membrane part CD19 molecule intersection_of: RO:0002104 PR:000001932 ! has plasma membrane part signal transducer CD24 intersection_of: RO:0002104 PR:000002037 ! has plasma membrane part complement component C1q receptor intersection_of: RO:0015016 PR:000001879 ! has low plasma membrane amount leukosialin +relationship: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha +relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002052 ! fraction D precursor B cell -relationship: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha -relationship: lacks_plasma_membrane_part PR:000001869 ! interleukin-7 receptor subunit alpha relationship: RO:0002104 PR:000001932 ! has plasma membrane part signal transducer CD24 relationship: RO:0002104 PR:000002037 ! has plasma membrane part complement component C1q receptor relationship: RO:0015016 PR:000001879 ! has low plasma membrane amount leukosialin @@ -26110,13 +15167,13 @@ def: "An immature B cell that is CD38-negative, CD10-low, CD21-low, and CD22-hig comment: Markers are associated with human cell type. is_a: CL:0000816 {is_inferred="true"} ! immature B cell intersection_of: CL:0000816 ! immature B cell -intersection_of: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +intersection_of: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 intersection_of: RO:0015015 PR:000001288 ! has high plasma membrane amount B-cell receptor CD22 intersection_of: RO:0015016 PR:000001338 ! has low plasma membrane amount complement receptor type 2 intersection_of: RO:0015016 PR:000001898 ! has low plasma membrane amount neprilysin +relationship: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002053 ! CD22-positive, CD38-low small pre-B cell -relationship: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 relationship: RO:0015015 PR:000001288 ! has high plasma membrane amount B-cell receptor CD22 relationship: RO:0015016 PR:000001338 ! has low plasma membrane amount complement receptor type 2 relationship: RO:0015016 PR:000001898 ! has low plasma membrane amount neprilysin @@ -26128,18 +15185,18 @@ name: fraction F mature B cell def: "A mature B cell subset originally defined as having being CD45R-positive, IgM-positive, IgD-positive and CD43-negative. Subsequent research demonstrated being CD21-positive and CD23-negative and CD93 negative." [GOC:tfm, PMID:17582343] is_a: CL:0000822 ! B-2 B cell intersection_of: CL:0000785 ! mature B cell -intersection_of: lacks_plasma_membrane_part PR:000001879 ! leukosialin -intersection_of: lacks_plasma_membrane_part PR:000001880 ! low affinity immunoglobulin epsilon Fc receptor -intersection_of: lacks_plasma_membrane_part PR:000002037 ! complement component C1q receptor +intersection_of: CL:4030046 PR:000001879 ! lacks_plasma_membrane_part leukosialin +intersection_of: CL:4030046 PR:000001880 ! lacks_plasma_membrane_part low affinity immunoglobulin epsilon Fc receptor +intersection_of: CL:4030046 PR:000002037 ! lacks_plasma_membrane_part complement component C1q receptor intersection_of: RO:0002104 GO:0071738 ! has plasma membrane part IgD immunoglobulin complex intersection_of: RO:0002104 GO:0071753 ! has plasma membrane part IgM immunoglobulin complex intersection_of: RO:0002104 PR:000001014 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RABC intersection_of: RO:0002104 PR:000001289 ! has plasma membrane part membrane-spanning 4-domains subfamily A member 1 intersection_of: RO:0002104 PR:000001338 ! has plasma membrane part complement receptor type 2 +relationship: CL:4030046 PR:000001880 ! lacks_plasma_membrane_part low affinity immunoglobulin epsilon Fc receptor +relationship: CL:4030046 PR:000002037 ! lacks_plasma_membrane_part complement component C1q receptor relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002054 ! fraction E immature B cell -relationship: lacks_plasma_membrane_part PR:000001880 ! low affinity immunoglobulin epsilon Fc receptor -relationship: lacks_plasma_membrane_part PR:000002037 ! complement component C1q receptor relationship: RO:0002104 GO:0071738 ! has plasma membrane part IgD immunoglobulin complex relationship: RO:0002104 GO:0071753 ! has plasma membrane part IgM immunoglobulin complex relationship: RO:0002104 PR:000001014 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RABC @@ -26156,12 +15213,12 @@ synonym: "CD16-negative monocyte" EXACT [] is_a: CL:0000860 {is_inferred="true"} ! classical monocyte is_a: CL:0001054 ! CD14-positive monocyte intersection_of: CL:0000860 ! classical monocyte -intersection_of: lacks_plasma_membrane_part PR:000001483 ! low affinity immunoglobulin gamma Fc region receptor III +intersection_of: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III intersection_of: RO:0002104 PR:000001465 ! has plasma membrane part high affinity immunoglobulin gamma Fc receptor I intersection_of: RO:0002104 PR:000001889 ! has plasma membrane part CD14 molecule intersection_of: RO:0002104 PR:000001925 ! has plasma membrane part scavenger receptor cysteine-rich type 1 protein M130 +relationship: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001483 ! low affinity immunoglobulin gamma Fc region receptor III relationship: RO:0002104 PR:000001465 ! has plasma membrane part high affinity immunoglobulin gamma Fc receptor I relationship: RO:0002104 PR:000001925 ! has plasma membrane part scavenger receptor cysteine-rich type 1 protein M130 creation_date: 2010-06-05T08:25:41Z @@ -26174,16 +15231,16 @@ comment: Markers are associated with mice. The Gr epitope is used to describe th is_a: CL:0000875 {is_inferred="true"} ! non-classical monocyte is_a: CL:0002398 ! Gr1-positive, CD43-positive monocyte intersection_of: CL:0000875 ! non-classical monocyte -intersection_of: lacks_plasma_membrane_part PR:000001014 ! receptor-type tyrosine-protein phosphatase C isoform CD45RABC +intersection_of: CL:4030046 PR:000001014 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RABC intersection_of: RO:0002104 PR:000001012 ! has plasma membrane part integrin alpha-M intersection_of: RO:0002104 PR:000001206 ! has plasma membrane part CX3C chemokine receptor 1 intersection_of: RO:0002104 PR:000001879 ! has plasma membrane part leukosialin intersection_of: RO:0002104 PR:000002062 ! has plasma membrane part macrophage colony-stimulating factor 1 receptor intersection_of: RO:0015016 PR:000001199 ! has low plasma membrane amount C-C chemokine receptor type 2 intersection_of: RO:0015016 PR:000002980 ! has low plasma membrane amount lymphocyte antigen 6C2 +relationship: CL:4030046 PR:000001014 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RABC relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002398 ! Gr1-positive, CD43-positive monocyte -relationship: lacks_plasma_membrane_part PR:000001014 ! receptor-type tyrosine-protein phosphatase C isoform CD45RABC relationship: RO:0002104 PR:000001206 ! has plasma membrane part CX3C chemokine receptor 1 relationship: RO:0015016 PR:000001199 ! has low plasma membrane amount C-C chemokine receptor type 2 relationship: RO:0015016 PR:000002980 ! has low plasma membrane amount lymphocyte antigen 6C2 @@ -26250,7 +15307,6 @@ synonym: "type I alveolar cells" EXACT [] synonym: "type I alveolar epithelial cells" EXACT [] xref: BTO:0000780 xref: FMA:62500 -is_a: BFO:0000040 ! material entity is_a: CL:0000322 ! pneumocyte intersection_of: CL:0000322 ! pneumocyte intersection_of: capable_of GO:0007585 ! respiratory gaseous exchange by respiratory system @@ -26485,7 +15541,6 @@ name: pancreatic ductal cell def: "Epithelial cell found in the ducts of the pancreas. This cell type contributes to the high luminal pH." [FMA:63099, GOC:tfm, PMID:14740223] subset: human_reference_atlas xref: FMA:63099 -is_a: BFO:0000040 ! material entity is_a: CL:0000069 ! branched duct epithelial cell is_a: CL:1001433 ! epithelial cell of exocrine pancreas intersection_of: CL:0000083 ! epithelial cell of pancreas @@ -26505,7 +15560,6 @@ subset: human_reference_atlas synonym: "centroacinar cell of Langerhans" EXACT [] synonym: "pancreatic centroacinar cell" EXACT [] xref: FMA:62455 -is_a: BFO:0000040 ! material entity is_a: CL:1001433 ! epithelial cell of exocrine pancreas intersection_of: CL:0000083 ! epithelial cell of pancreas intersection_of: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity @@ -26597,9 +15651,9 @@ synonym: "agranular leukocyte" EXACT [] xref: FMA:62855 is_a: CL:0000738 {is_inferred="true"} ! leukocyte intersection_of: CL:0000738 ! leukocyte -intersection_of: lacks_part GO:0030141 ! secretory granule +intersection_of: CL:4030045 GO:0030141 ! lacks_part secretory granule +relationship: CL:4030045 GO:0030141 ! lacks_part secretory granule relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_part GO:0030141 ! secretory granule creation_date: 2010-07-22T11:30:33Z [Term] @@ -26612,7 +15666,6 @@ synonym: "ICC" EXACT [] synonym: "intestinal pacemaker cell" EXACT [GOC:pr] xref: BTO:0003914 xref: FMA:86573 -is_a: BFO:0000040 ! material entity is_a: CL:0000710 {is_inferred="true"} ! neurecto-epithelial cell intersection_of: CL:0000710 ! neurecto-epithelial cell intersection_of: capable_of GO:0043134 ! regulation of hindgut contraction @@ -26632,35 +15685,35 @@ is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0001069 ! group 2 innate lymphoid cell intersection_of: capable_of GO:0002830 ! positive regulation of type 2 immune response intersection_of: capable_of GO:0032616 ! interleukin-13 production +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001008 ! lacks_plasma_membrane_part integrin alpha-2 +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001326 ! lacks_plasma_membrane_part bone marrow stromal antigen 2 +intersection_of: CL:4030046 PR:000001893 ! lacks_plasma_membrane_part natural cytotoxicity triggering receptor 1 +intersection_of: CL:4030046 PR:000001927 ! lacks_plasma_membrane_part sialic acid-binding Ig-like lectin 5 +intersection_of: CL:4030046 PR:000007431 ! lacks_plasma_membrane_part high affinity immunoglobulin epsilon receptor subunit alpha intersection_of: in_taxon NCBITaxon:10090 ! Mus musculus -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001008 ! integrin alpha-2 -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001326 ! bone marrow stromal antigen 2 -intersection_of: lacks_plasma_membrane_part PR:000001893 ! natural cytotoxicity triggering receptor 1 -intersection_of: lacks_plasma_membrane_part PR:000001927 ! sialic acid-binding Ig-like lectin 5 -intersection_of: lacks_plasma_membrane_part PR:000007431 ! high affinity immunoglobulin epsilon receptor subunit alpha intersection_of: RO:0002104 PR:000001860 ! has plasma membrane part inducible T-cell costimulator intersection_of: RO:0002104 PR:000001869 ! has plasma membrane part interleukin-7 receptor subunit alpha intersection_of: RO:0002104 PR:000008982 ! has plasma membrane part interleukin-17 receptor B intersection_of: RO:0002104 PR:000008994 ! has plasma membrane part interleukin-1 receptor-like 1 relationship: capable_of GO:0002830 ! positive regulation of type 2 immune response relationship: capable_of GO:0032616 ! interleukin-13 production +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001008 ! lacks_plasma_membrane_part integrin alpha-2 +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001326 ! lacks_plasma_membrane_part bone marrow stromal antigen 2 +relationship: CL:4030046 PR:000001893 ! lacks_plasma_membrane_part natural cytotoxicity triggering receptor 1 +relationship: CL:4030046 PR:000001927 ! lacks_plasma_membrane_part sialic acid-binding Ig-like lectin 5 +relationship: CL:4030046 PR:000007431 ! lacks_plasma_membrane_part high affinity immunoglobulin epsilon receptor subunit alpha relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: in_taxon NCBITaxon:10090 ! Mus musculus -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001008 ! integrin alpha-2 -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001326 ! bone marrow stromal antigen 2 -relationship: lacks_plasma_membrane_part PR:000001893 ! natural cytotoxicity triggering receptor 1 -relationship: lacks_plasma_membrane_part PR:000001927 ! sialic acid-binding Ig-like lectin 5 -relationship: lacks_plasma_membrane_part PR:000007431 ! high affinity immunoglobulin epsilon receptor subunit alpha relationship: RO:0002104 PR:000001860 ! has plasma membrane part inducible T-cell costimulator relationship: RO:0002104 PR:000001869 ! has plasma membrane part interleukin-7 receptor subunit alpha relationship: RO:0002104 PR:000008982 ! has plasma membrane part interleukin-17 receptor B @@ -26751,6 +15804,7 @@ name: internodal tract myocyte def: "A specialised myocyte that lies between the sinoatrial node and the atrioventricular node and is involved in the conduction of electrical signals." [GOC:tfm, ISBN:0781729300] xref: FMA:223275 is_a: CL:0002086 ! specialized cardiac myocyte +is_a: CL:0008009 ! transversely striated visceral muscle cell intersection_of: CL:0000187 ! muscle cell intersection_of: part_of UBERON:0009966 ! internodal tract relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 @@ -26836,8 +15890,8 @@ synonym: "CD38-negative naive B-cell" EXACT [] synonym: "CD38-negative naive B-lymphocyte" EXACT [] is_a: CL:0000788 {is_inferred="true"} ! naive B cell intersection_of: CL:0000788 ! naive B cell -intersection_of: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 -relationship: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +intersection_of: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +relationship: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 [Term] id: CL:0002103 @@ -26884,8 +15938,8 @@ synonym: "IgG-negative double negative memory B-cell" EXACT [] synonym: "IgG-negative double negative memory B-lymphocyte" EXACT [] is_a: CL:0000981 {is_inferred="true"} ! double negative memory B cell intersection_of: CL:0000981 ! double negative memory B cell -intersection_of: lacks_plasma_membrane_part GO:0071735 ! IgG immunoglobulin complex -relationship: lacks_plasma_membrane_part GO:0071735 ! IgG immunoglobulin complex +intersection_of: CL:4030046 GO:0071735 ! lacks_plasma_membrane_part IgG immunoglobulin complex +relationship: CL:4030046 GO:0071735 ! lacks_plasma_membrane_part IgG immunoglobulin complex [Term] id: CL:0002105 @@ -26919,7 +15973,7 @@ def: "An IgD-negative CD38-positive IgG memory B cell is a CD38-positive IgG-pos is_a: CL:0001053 ! IgD-negative memory B cell is_a: CL:0002105 {is_inferred="true"} ! CD38-positive IgG memory B cell intersection_of: CL:0002105 ! CD38-positive IgG memory B cell -intersection_of: lacks_plasma_membrane_part GO:0071738 ! IgD immunoglobulin complex +intersection_of: CL:4030046 GO:0071738 ! lacks_plasma_membrane_part IgD immunoglobulin complex [Term] id: CL:0002108 @@ -26928,9 +15982,9 @@ def: "A CD38-negative IgG memory B cell is a IgG-positive class switched memory is_a: CL:0000979 {is_inferred="true"} ! IgG memory B cell is_a: CL:0001053 ! IgD-negative memory B cell intersection_of: CL:0000979 ! IgG memory B cell -intersection_of: lacks_plasma_membrane_part GO:0071738 ! IgD immunoglobulin complex -intersection_of: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 -relationship: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +intersection_of: CL:4030046 GO:0071738 ! lacks_plasma_membrane_part IgD immunoglobulin complex +intersection_of: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +relationship: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 [Term] id: CL:0002109 @@ -26974,8 +16028,8 @@ synonym: "CD38-negative unswitched memory B-cell" EXACT [] synonym: "CD38-negative unswitched memory B-lymphocyte" EXACT [] is_a: CL:0000970 {is_inferred="true"} ! unswitched memory B cell intersection_of: CL:0000970 ! unswitched memory B cell -intersection_of: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 -relationship: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +intersection_of: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +relationship: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 [Term] id: CL:0002112 @@ -27042,8 +16096,8 @@ synonym: "IgG-negative class switched memory B-cell" EXACT [] synonym: "IgG-negative class switched memory B-lymphocyte" EXACT [] is_a: CL:0000972 {is_inferred="true"} ! class switched memory B cell intersection_of: CL:0000972 ! class switched memory B cell -intersection_of: lacks_plasma_membrane_part GO:0071735 ! IgG immunoglobulin complex -relationship: lacks_plasma_membrane_part GO:0071735 ! IgG immunoglobulin complex +intersection_of: CL:4030046 GO:0071735 ! lacks_plasma_membrane_part IgG immunoglobulin complex +relationship: CL:4030046 GO:0071735 ! lacks_plasma_membrane_part IgG immunoglobulin complex [Term] id: CL:0002118 @@ -27051,8 +16105,8 @@ name: CD38-negative IgG-negative class switched memory B cell def: "A CD38-negative IgG-negative memory B cell is a IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-negative and IgG-negative." [GOC:dsd, GOC:rhs, GOC:tfm, PMID:20123131] is_a: CL:0002117 {is_inferred="true"} ! IgG-negative class switched memory B cell intersection_of: CL:0002117 ! IgG-negative class switched memory B cell -intersection_of: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 -relationship: lacks_plasma_membrane_part PR:000001408 ! ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +intersection_of: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 +relationship: CL:4030046 PR:000001408 ! lacks_plasma_membrane_part ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 [Term] id: CL:0002119 @@ -27078,8 +16132,8 @@ name: CD24-negative CD38-negative IgG-negative class switched memory B cell def: "A CD24-negative CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-negative, CD38-negative, and IgG-negative." [GOC:dsd, GOC:rhs, GOC:tfm, PMID:20123131] is_a: CL:0002118 {is_inferred="true"} ! CD38-negative IgG-negative class switched memory B cell intersection_of: CL:0002118 ! CD38-negative IgG-negative class switched memory B cell -intersection_of: lacks_plasma_membrane_part PR:000001932 ! signal transducer CD24 -relationship: lacks_plasma_membrane_part PR:000001932 ! signal transducer CD24 +intersection_of: CL:4030046 PR:000001932 ! lacks_plasma_membrane_part signal transducer CD24 +relationship: CL:4030046 PR:000001932 ! lacks_plasma_membrane_part signal transducer CD24 [Term] id: CL:0002122 @@ -27125,14 +16179,14 @@ synonym: "gammadelta-17 cells" EXACT [PMID:21976777] is_a: CL:0000800 {is_inferred="true"} ! mature gamma-delta T cell intersection_of: CL:0000800 ! mature gamma-delta T cell intersection_of: capable_of GO:0032620 ! interleukin-17 production +intersection_of: CL:4030046 PR:000001963 ! lacks_plasma_membrane_part CD27 molecule intersection_of: has_part PR:000003455 ! nuclear receptor ROR-gamma isoform 2 -intersection_of: lacks_plasma_membrane_part PR:000001963 ! CD27 molecule intersection_of: output_of GO:0030217 ! T cell differentiation relationship: capable_of GO:0032620 ! interleukin-17 production +relationship: CL:4030046 PR:000001963 ! lacks_plasma_membrane_part CD27 molecule relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002126 ! CD25-positive, CD27-positive immature gamma-delta T cell relationship: has_part PR:000003455 ! nuclear receptor ROR-gamma isoform 2 -relationship: lacks_plasma_membrane_part PR:000001963 ! CD27 molecule relationship: output_of GO:0030217 ! T cell differentiation creation_date: 2010-08-18T09:57:29Z @@ -27188,11 +16242,11 @@ synonym: "Th17 non-TFH CD8-positive T cell" EXACT [] is_a: CL:0000908 {is_inferred="true"} ! CD8-positive, alpha-beta cytokine secreting effector T cell intersection_of: CL:0000908 ! CD8-positive, alpha-beta cytokine secreting effector T cell intersection_of: capable_of GO:0032620 ! interleukin-17 production -intersection_of: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA +intersection_of: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA intersection_of: RO:0002104 PR:000001202 ! has plasma membrane part C-C chemokine receptor type 6 intersection_of: RO:0015015 PR:000001201 ! has high plasma membrane amount C-C chemokine receptor type 5 relationship: capable_of GO:0032620 ! interleukin-17 production -relationship: lacks_plasma_membrane_part PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA +relationship: CL:4030046 PR:000001015 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RA relationship: RO:0002104 PR:000001202 ! has plasma membrane part C-C chemokine receptor type 6 relationship: RO:0015015 PR:000001201 ! has high plasma membrane amount C-C chemokine receptor type 5 @@ -28937,7 +17991,6 @@ synonym: "PP-cell of pancreatic islet" EXACT [] xref: BTO:0000805 xref: FMA:70588 xref: MESH:D050418 -is_a: CL:0000083 ! epithelial cell of pancreas is_a: CL:0000696 ! PP cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0000696 ! PP cell @@ -29237,7 +18290,6 @@ synonym: "fibroblast-like synoviocyte" EXACT [] synonym: "synovial fibroblast" EXACT [PMID:23147896] xref: BTO:0003652 xref: FMA:66788 -is_a: BFO:0000040 ! material entity is_a: CL:0000214 ! synovial cell is_a: CL:0000499 ! stromal cell intersection_of: CL:0000499 ! stromal cell @@ -29480,7 +18532,6 @@ name: neural cell def: "A cell that is part of the nervous system." [GOC:tfm, ISBN:0618947256] xref: CALOHA:TS-2040 xref: FMA:70333 -is_a: BFO:0000004 ! independent continuant is_a: CL:0000548 ! animal cell is_a: CL:0002371 ! somatic cell intersection_of: CL:0000548 ! animal cell @@ -29497,7 +18548,6 @@ def: "A cell of the supporting or framework tissue of the body, arising chiefly xref: CALOHA:TS-2096 xref: FMA:63875 xref: MESH:D003239 -is_a: BFO:0000004 ! independent continuant is_a: CL:0000548 ! animal cell is_a: CL:0002371 {is_inferred="true"} ! somatic cell intersection_of: CL:0002371 ! somatic cell @@ -29538,7 +18588,6 @@ id: CL:0002323 name: amniocyte def: "A cell of a fetus which is suspended in the amniotic fluid. Amniocytes are considered to arise from several tissues including fetal skin, the fetal urinary tract, umbilical cord, and the inner amniotic surface." [BFO:0000066, GOC:tfm, PMID:3211847] xref: BTO:0000066 -is_a: BFO:0000040 ! material entity is_a: CL:0000349 {is_inferred="true"} ! extraembryonic cell intersection_of: CL:0000349 ! extraembryonic cell intersection_of: located_in UBERON:0000173 ! amniotic fluid @@ -29712,16 +18761,16 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000823 ! immature natural killer cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000823 ! immature natural killer cell +intersection_of: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule intersection_of: in_taxon NCBITaxon:9606 ! Homo sapiens -intersection_of: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule intersection_of: RO:0002104 PR:000001024 ! has plasma membrane part neural cell adhesion molecule 1 intersection_of: RO:0002104 PR:000001381 ! has plasma membrane part interleukin-2 receptor subunit beta intersection_of: RO:0002104 PR:000001874 ! has plasma membrane part KLRB1-like protein intersection_of: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor +relationship: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002344 ! CD56-negative, CD161-positive immature natural killer cell, human relationship: in_taxon NCBITaxon:9606 ! Homo sapiens -relationship: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule relationship: RO:0002104 PR:000001024 ! has plasma membrane part neural cell adhesion molecule 1 relationship: RO:0002104 PR:000001381 ! has plasma membrane part interleukin-2 receptor subunit beta relationship: RO:0002104 PR:000001874 ! has plasma membrane part KLRB1-like protein @@ -29778,13 +18827,13 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000824 ! mature natural killer cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000824 ! mature natural killer cell +intersection_of: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III intersection_of: in_taxon NCBITaxon:9606 ! Homo sapiens -intersection_of: lacks_plasma_membrane_part PR:000001483 ! low affinity immunoglobulin gamma Fc region receptor III intersection_of: RO:0002104 PR:000009766 ! has plasma membrane part galectin-1 intersection_of: RO:0015015 PR:000001024 ! has high plasma membrane amount neural cell adhesion molecule 1 +relationship: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: in_taxon NCBITaxon:9606 ! Homo sapiens -relationship: lacks_plasma_membrane_part PR:000001483 ! low affinity immunoglobulin gamma Fc region receptor III relationship: RO:0002104 PR:000009766 ! has plasma membrane part galectin-1 relationship: RO:0015015 PR:000001024 ! has high plasma membrane amount neural cell adhesion molecule 1 creation_date: 2010-09-20T04:00:02Z @@ -29799,16 +18848,16 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000823 ! immature natural killer cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000823 ! immature natural killer cell +intersection_of: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule +intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: in_taxon NCBITaxon:9606 ! Homo sapiens -intersection_of: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule -intersection_of: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 intersection_of: RO:0002104 PR:000001381 ! has plasma membrane part interleukin-2 receptor subunit beta intersection_of: RO:0002104 PR:000001874 ! has plasma membrane part KLRB1-like protein intersection_of: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor +relationship: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule +relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: in_taxon NCBITaxon:9606 ! Homo sapiens -relationship: lacks_plasma_membrane_part PR:000001003 ! CD34 molecule -relationship: lacks_plasma_membrane_part PR:000001024 ! neural cell adhesion molecule 1 relationship: RO:0002104 PR:000001381 ! has plasma membrane part interleukin-2 receptor subunit beta relationship: RO:0002104 PR:000001874 ! has plasma membrane part KLRB1-like protein relationship: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor @@ -29848,12 +18897,12 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000823 ! immature natural killer cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000823 ! immature natural killer cell +intersection_of: CL:4030046 PR:000001008 ! lacks_plasma_membrane_part integrin alpha-2 intersection_of: in_taxon NCBITaxon:10090 ! Mus musculus -intersection_of: lacks_plasma_membrane_part PR:000001008 ! integrin alpha-2 intersection_of: RO:0002104 PR:000002977 ! has plasma membrane part killer cell lectin-like receptor subfamily B member 1C +relationship: CL:4030046 PR:000001008 ! lacks_plasma_membrane_part integrin alpha-2 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: in_taxon NCBITaxon:10090 ! Mus musculus -relationship: lacks_plasma_membrane_part PR:000001008 ! integrin alpha-2 relationship: RO:0002104 PR:000002977 ! has plasma membrane part killer cell lectin-like receptor subfamily B member 1C creation_date: 2010-09-21T10:11:44Z @@ -29958,17 +19007,17 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0002352 {is_inferred="true"} ! gestational hematopoietic stem cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0002352 ! gestational hematopoietic stem cell -intersection_of: lacks_plasma_membrane_part PR:000001308 ! CD48 molecule -intersection_of: lacks_plasma_membrane_part PR:000001896 ! natural killer cell receptor 2B4 +intersection_of: CL:4030046 PR:000001308 ! lacks_plasma_membrane_part CD48 molecule +intersection_of: CL:4030046 PR:000001896 ! lacks_plasma_membrane_part natural killer cell receptor 2B4 intersection_of: RO:0002104 GO:0042611 ! has plasma membrane part MHC protein complex intersection_of: RO:0002104 PR:000001006 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C intersection_of: RO:0002104 PR:000001833 ! has plasma membrane part SLAM family member 1 intersection_of: RO:0002104 PR:000001932 ! has plasma membrane part signal transducer CD24 intersection_of: RO:0002104 PR:000002037 ! has plasma membrane part complement component C1q receptor intersection_of: RO:0002104 PR:000002979 ! has plasma membrane part lymphocyte antigen 6A-2/6E-1 +relationship: CL:4030046 PR:000001308 ! lacks_plasma_membrane_part CD48 molecule +relationship: CL:4030046 PR:000001896 ! lacks_plasma_membrane_part natural killer cell receptor 2B4 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001308 ! CD48 molecule -relationship: lacks_plasma_membrane_part PR:000001896 ! natural killer cell receptor 2B4 relationship: part_of UBERON:0002107 ! liver relationship: RO:0002104 GO:0042611 ! has plasma membrane part MHC protein complex relationship: RO:0002104 PR:000001006 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C @@ -29987,16 +19036,16 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0002352 {is_inferred="true"} ! gestational hematopoietic stem cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0002352 ! gestational hematopoietic stem cell -intersection_of: lacks_plasma_membrane_part GO:0042611 ! MHC protein complex -intersection_of: lacks_plasma_membrane_part PR:000001006 ! receptor-type tyrosine-protein phosphatase C -intersection_of: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 +intersection_of: CL:4030046 GO:0042611 ! lacks_plasma_membrane_part MHC protein complex +intersection_of: CL:4030046 PR:000001006 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C +intersection_of: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 intersection_of: RO:0002104 PR:000001307 ! has plasma membrane part CD44 molecule intersection_of: RO:0002104 PR:000001932 ! has plasma membrane part signal transducer CD24 intersection_of: RO:0002104 PR:000002037 ! has plasma membrane part complement component C1q receptor +relationship: CL:4030046 GO:0042611 ! lacks_plasma_membrane_part MHC protein complex +relationship: CL:4030046 PR:000001006 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C +relationship: CL:4030046 PR:000002979 ! lacks_plasma_membrane_part lymphocyte antigen 6A-2/6E-1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part GO:0042611 ! MHC protein complex -relationship: lacks_plasma_membrane_part PR:000001006 ! receptor-type tyrosine-protein phosphatase C -relationship: lacks_plasma_membrane_part PR:000002979 ! lymphocyte antigen 6A-2/6E-1 relationship: part_of UBERON:0001040 ! yolk sac relationship: RO:0002104 PR:000001307 ! has plasma membrane part CD44 molecule relationship: RO:0002104 PR:000001932 ! has plasma membrane part signal transducer CD24 @@ -30011,6 +19060,7 @@ synonym: "primitive erythroblast" EXACT [] synonym: "primitive erythrocyte" EXACT [] synonym: "primitive erythroid cell" EXACT [] is_a: CL:0002417 {is_inferred="true"} ! primitive erythroid lineage cell +is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0002417 ! primitive erythroid lineage cell intersection_of: bearer_of PATO:0000586 ! increased size intersection_of: has_part PR:000008467 ! hemoglobin subunit zeta @@ -30094,6 +19144,7 @@ synonym: "EryP-CFC" EXACT [] synonym: "inner blood island hemangioblast" EXACT [] is_a: CARO:0000006 ! material anatomical entity is_a: CL:0002417 {is_inferred="true"} ! primitive erythroid lineage cell +is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0002417 ! primitive erythroid lineage cell intersection_of: RO:0002104 PR:000009127 ! has plasma membrane part integrin alpha-IIb relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 @@ -30429,18 +19480,18 @@ name: intermediate monocyte def: "A monocyte that has characteristics of both patrolling and inflammatory monocytes." [GOC:tfm, PMID:20628149, PMID:20870168] is_a: CL:0000576 ! monocyte intersection_of: CL:0000576 ! monocyte -intersection_of: has_not_completed GO:0030224 ! monocyte differentiation -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001199 ! C-C chemokine receptor type 2 -intersection_of: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 +intersection_of: CL:4030044 GO:0030224 ! has_not_completed monocyte differentiation +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001199 ! lacks_plasma_membrane_part C-C chemokine receptor type 2 +intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 +relationship: CL:4030044 GO:0030224 ! has_not_completed monocyte differentiation +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001199 ! lacks_plasma_membrane_part C-C chemokine receptor type 2 +relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000860 ! classical monocyte -relationship: has_not_completed GO:0030224 ! monocyte differentiation -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001199 ! C-C chemokine receptor type 2 -relationship: lacks_plasma_membrane_part PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 creation_date: 2010-10-04T10:52:03Z [Term] @@ -30471,16 +19522,16 @@ comment: Markers are associated with mice. The Gr epitope is used to describe th is_a: CL:0000860 {is_inferred="true"} ! classical monocyte is_a: CL:0001022 ! CD115-positive monocyte intersection_of: CL:0000860 ! classical monocyte -intersection_of: lacks_plasma_membrane_part PR:000001014 ! receptor-type tyrosine-protein phosphatase C isoform CD45RABC -intersection_of: lacks_plasma_membrane_part PR:000001206 ! CX3C chemokine receptor 1 -intersection_of: lacks_plasma_membrane_part PR:000001879 ! leukosialin +intersection_of: CL:4030046 PR:000001014 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RABC +intersection_of: CL:4030046 PR:000001206 ! lacks_plasma_membrane_part CX3C chemokine receptor 1 +intersection_of: CL:4030046 PR:000001879 ! lacks_plasma_membrane_part leukosialin intersection_of: RO:0002104 PR:000001012 ! has plasma membrane part integrin alpha-M intersection_of: RO:0002104 PR:000002062 ! has plasma membrane part macrophage colony-stimulating factor 1 receptor intersection_of: RO:0015015 PR:000002980 ! has high plasma membrane amount lymphocyte antigen 6C2 +relationship: CL:4030046 PR:000001014 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RABC +relationship: CL:4030046 PR:000001206 ! lacks_plasma_membrane_part CX3C chemokine receptor 1 +relationship: CL:4030046 PR:000001879 ! lacks_plasma_membrane_part leukosialin relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001014 ! receptor-type tyrosine-protein phosphatase C isoform CD45RABC -relationship: lacks_plasma_membrane_part PR:000001206 ! CX3C chemokine receptor 1 -relationship: lacks_plasma_membrane_part PR:000001879 ! leukosialin relationship: RO:0015015 PR:000002980 ! has high plasma membrane amount lymphocyte antigen 6C2 creation_date: 2010-10-04T11:26:18Z @@ -30511,10 +19562,10 @@ comment: This cell type is compatible with the HIPC Lyoplate markers for 'CD16+ synonym: "CD16+ monocyte" EXACT [PMID:22343568] is_a: CL:0001054 ! CD14-positive monocyte intersection_of: CL:0001054 ! CD14-positive monocyte -intersection_of: lacks_plasma_membrane_part PR:000001199 ! C-C chemokine receptor type 2 +intersection_of: CL:4030046 PR:000001199 ! lacks_plasma_membrane_part C-C chemokine receptor type 2 intersection_of: RO:0002104 PR:000001483 ! has plasma membrane part low affinity immunoglobulin gamma Fc region receptor III +relationship: CL:4030046 PR:000001199 ! lacks_plasma_membrane_part C-C chemokine receptor type 2 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001199 ! C-C chemokine receptor type 2 relationship: RO:0002104 PR:000001483 ! has plasma membrane part low affinity immunoglobulin gamma Fc region receptor III creation_date: 2010-10-04T12:49:47Z @@ -30557,7 +19608,7 @@ name: fraction B/C precursor B cell def: "A precursor B cell that is AA4-positive, IgM-negative, CD19-positive, CD43-positive and HSA-positive." [GOC:tfm, http://www.immgen.org/index_content.html] is_a: CL:0000817 {is_inferred="true"} ! precursor B cell intersection_of: CL:0000817 ! precursor B cell -intersection_of: lacks_plasma_membrane_part GO:0071753 ! IgM immunoglobulin complex +intersection_of: CL:4030046 GO:0071753 ! lacks_plasma_membrane_part IgM immunoglobulin complex intersection_of: RO:0002104 PR:000001002 ! has plasma membrane part CD19 molecule intersection_of: RO:0002104 PR:000001879 ! has plasma membrane part leukosialin intersection_of: RO:0002104 PR:000001932 ! has plasma membrane part signal transducer CD24 @@ -30588,17 +19639,17 @@ synonym: "Peyers patch B cell" EXACT [] is_a: CL:0000822 ! B-2 B cell is_a: CL:0009014 ! Peyer's patch lymphocyte intersection_of: CL:0000785 ! mature B cell -intersection_of: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -intersection_of: lacks_plasma_membrane_part PR:000001879 ! leukosialin -intersection_of: lacks_plasma_membrane_part PR:000002037 ! complement component C1q receptor +intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +intersection_of: CL:4030046 PR:000001879 ! lacks_plasma_membrane_part leukosialin +intersection_of: CL:4030046 PR:000002037 ! lacks_plasma_membrane_part complement component C1q receptor intersection_of: part_of UBERON:0001211 ! Peyer's patch intersection_of: RO:0002104 GO:0071753 ! has plasma membrane part IgM immunoglobulin complex intersection_of: RO:0002104 PR:000001014 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RABC intersection_of: RO:0002104 PR:000001289 ! has plasma membrane part membrane-spanning 4-domains subfamily A member 1 intersection_of: RO:0002104 PR:000001338 ! has plasma membrane part complement receptor type 2 +relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 +relationship: CL:4030046 PR:000002037 ! lacks_plasma_membrane_part complement component C1q receptor relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001839 ! T-cell surface glycoprotein CD5 -relationship: lacks_plasma_membrane_part PR:000002037 ! complement component C1q receptor relationship: RO:0002104 GO:0071753 ! has plasma membrane part IgM immunoglobulin complex relationship: RO:0002104 PR:000001014 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C isoform CD45RABC relationship: RO:0002104 PR:000001338 ! has plasma membrane part complement receptor type 2 @@ -30632,8 +19683,8 @@ synonym: "gd thymocyte" EXACT [] is_a: CL:0000798 ! gamma-delta T cell is_a: CL:0002489 ! double negative thymocyte intersection_of: CL:0000893 ! thymocyte -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000025402 ! T cell receptor co-receptor CD8 +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000025402 ! lacks_plasma_membrane_part T cell receptor co-receptor CD8 intersection_of: RO:0002104 GO:0042106 ! has plasma membrane part gamma-delta T cell receptor complex relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-10-07T02:33:39Z @@ -30794,9 +19845,9 @@ xref: BTO:0001372 xref: CALOHA:TS-1042 is_a: CL:0000084 {is_inferred="true"} ! T cell intersection_of: CL:0000084 ! T cell -intersection_of: has_not_completed GO:0045058 ! T cell selection +intersection_of: CL:4030044 GO:0045058 ! has_not_completed T cell selection +relationship: CL:4030044 GO:0045058 ! has_not_completed T cell selection relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: has_not_completed GO:0045058 ! T cell selection creation_date: 2010-10-12T01:56:17Z [Term] @@ -30862,12 +19913,12 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000827 {is_inferred="true"} ! pro-T cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000827 ! pro-T cell -intersection_of: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha +intersection_of: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha intersection_of: RO:0002104 PR:000001307 ! has plasma membrane part CD44 molecule intersection_of: RO:0002104 PR:000001869 ! has plasma membrane part interleukin-7 receptor subunit alpha intersection_of: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor +relationship: CL:4030046 PR:000001380 ! lacks_plasma_membrane_part interleukin-2 receptor subunit alpha relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001380 ! interleukin-2 receptor subunit alpha relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: RO:0002104 PR:000001307 ! has plasma membrane part CD44 molecule relationship: RO:0002104 PR:000001869 ! has plasma membrane part interleukin-7 receptor subunit alpha @@ -31139,13 +20190,13 @@ synonym: "CD94- Ly49I-negative NK cell" EXACT [] synonym: "NK.49Cl-94-.Sp" EXACT [] is_a: CL:0000623 ! natural killer cell intersection_of: CL:0000623 ! natural killer cell +intersection_of: CL:4030046 PR:000001402 ! lacks_plasma_membrane_part killer cell lectin-like receptor subfamily D member 1 +intersection_of: CL:4030046 PR:000009618 ! lacks_plasma_membrane_part killer cell lectin-like receptor 3 intersection_of: in_taxon NCBITaxon:10090 ! Mus musculus -intersection_of: lacks_plasma_membrane_part PR:000001402 ! killer cell lectin-like receptor subfamily D member 1 -intersection_of: lacks_plasma_membrane_part PR:000009618 ! killer cell lectin-like receptor 3 +relationship: CL:4030046 PR:000001402 ! lacks_plasma_membrane_part killer cell lectin-like receptor subfamily D member 1 +relationship: CL:4030046 PR:000009618 ! lacks_plasma_membrane_part killer cell lectin-like receptor 3 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: in_taxon NCBITaxon:10090 ! Mus musculus -relationship: lacks_plasma_membrane_part PR:000001402 ! killer cell lectin-like receptor subfamily D member 1 -relationship: lacks_plasma_membrane_part PR:000009618 ! killer cell lectin-like receptor 3 creation_date: 2010-10-25T03:56:21Z [Term] @@ -31182,10 +20233,10 @@ def: "A NK1.1-positive T cell that is Ly49D-negative." [GOC:tfm, http://www.immg synonym: "NK.49D-.Sp" EXACT [] is_a: CL:0002438 ! NK1.1-positive natural killer cell, mouse intersection_of: CL:0002438 ! NK1.1-positive natural killer cell, mouse +intersection_of: CL:4030046 PR:000009619 ! lacks_plasma_membrane_part killer cell lectin-like receptor 4 intersection_of: in_taxon NCBITaxon:10090 ! Mus musculus -intersection_of: lacks_plasma_membrane_part PR:000009619 ! killer cell lectin-like receptor 4 +relationship: CL:4030046 PR:000009619 ! lacks_plasma_membrane_part killer cell lectin-like receptor 4 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000009619 ! killer cell lectin-like receptor 4 creation_date: 2010-10-25T03:39:02Z [Term] @@ -31196,10 +20247,10 @@ synonym: "Ly49I-negative NK cell" EXACT [] synonym: "NK.49Cl-.Sp" EXACT [] is_a: CL:0002438 ! NK1.1-positive natural killer cell, mouse intersection_of: CL:0002438 ! NK1.1-positive natural killer cell, mouse +intersection_of: CL:4030046 PR:000009618 ! lacks_plasma_membrane_part killer cell lectin-like receptor 3 intersection_of: in_taxon NCBITaxon:10090 ! Mus musculus -intersection_of: lacks_plasma_membrane_part PR:000009618 ! killer cell lectin-like receptor 3 +relationship: CL:4030046 PR:000009618 ! lacks_plasma_membrane_part killer cell lectin-like receptor 3 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000009618 ! killer cell lectin-like receptor 3 creation_date: 2010-10-25T03:52:04Z [Term] @@ -31209,10 +20260,10 @@ def: "A NK1.1-positive T cell that is CD94-negative." [GOC:tfm, http://www.immge synonym: "NK.94-.Sp" EXACT [] is_a: CL:0002438 ! NK1.1-positive natural killer cell, mouse intersection_of: CL:0002438 ! NK1.1-positive natural killer cell, mouse +intersection_of: CL:4030046 PR:000001402 ! lacks_plasma_membrane_part killer cell lectin-like receptor subfamily D member 1 intersection_of: in_taxon NCBITaxon:10090 ! Mus musculus -intersection_of: lacks_plasma_membrane_part PR:000001402 ! killer cell lectin-like receptor subfamily D member 1 +relationship: CL:4030046 PR:000001402 ! lacks_plasma_membrane_part killer cell lectin-like receptor subfamily D member 1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001402 ! killer cell lectin-like receptor subfamily D member 1 creation_date: 2010-10-25T03:54:18Z [Term] @@ -31222,10 +20273,10 @@ def: "A NK1.1-positive T cell that is Ly49H-negative." [GOC:tfm, http://www.immg synonym: "LyH49H-negative" EXACT [] is_a: CL:0002438 ! NK1.1-positive natural killer cell, mouse intersection_of: CL:0002438 ! NK1.1-positive natural killer cell, mouse +intersection_of: CL:4030046 PR:000009623 ! lacks_plasma_membrane_part killer cell lectin-like receptor 8 intersection_of: in_taxon NCBITaxon:10090 ! Mus musculus -intersection_of: lacks_plasma_membrane_part PR:000009623 ! killer cell lectin-like receptor 8 +relationship: CL:4030046 PR:000009623 ! lacks_plasma_membrane_part killer cell lectin-like receptor 8 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000009623 ! killer cell lectin-like receptor 8 creation_date: 2010-10-25T03:42:42Z [Term] @@ -31282,11 +20333,11 @@ synonym: "DC.8-4-11b+" EXACT [] synonym: "spleen double-negative dendritic cell" EXACT [] is_a: CL:0002465 {is_inferred="true"} ! CD11b-positive dendritic cell intersection_of: CL:0002465 ! CD11b-positive dendritic cell -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain creation_date: 2010-11-22T01:10:28Z [Term] @@ -31296,10 +20347,10 @@ def: "A CD11c-low plasmacytoid dendritic cell that is CD8alpha-negative and CD4- synonym: "DC.pDC.8-" EXACT [] is_a: CL:0000989 {is_inferred="true"} ! CD11c-low plasmacytoid dendritic cell intersection_of: CL:0000989 ! CD11c-low plasmacytoid dendritic cell -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: RO:0002104 PR:000001004 ! has plasma membrane part CD4 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain relationship: RO:0002104 PR:000001004 ! has plasma membrane part CD4 molecule creation_date: 2010-11-22T01:27:37Z @@ -31353,10 +20404,10 @@ name: langerin-negative dermal dendritic cell def: "A dermal dendritic cell that is langerin-negative, CD103-negative, and CD11b-positive." [GOC:tfm, http://www.immgen.org/index_content.html] is_a: CL:0001006 {is_inferred="true"} ! dermal dendritic cell intersection_of: CL:0001006 ! dermal dendritic cell -intersection_of: lacks_plasma_membrane_part PR:000001010 ! integrin alpha-E +intersection_of: CL:4030046 PR:000001010 ! lacks_plasma_membrane_part integrin alpha-E intersection_of: RO:0002104 PR:000001012 ! has plasma membrane part integrin alpha-M +relationship: CL:4030046 PR:000001010 ! lacks_plasma_membrane_part integrin alpha-E relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001010 ! integrin alpha-E creation_date: 2010-11-22T04:09:44Z [Term] @@ -31367,9 +20418,9 @@ subset: human_reference_atlas synonym: "DC.8-.Th" EXACT [] is_a: CL:0000941 {is_inferred="true"} ! thymic conventional dendritic cell intersection_of: CL:0000941 ! thymic conventional dendritic cell -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens creation_date: 2010-11-23T10:58:53Z @@ -31394,11 +20445,11 @@ is_a: CL:0000766 ! myeloid leukocyte is_a: CL:0000990 {is_inferred="true"} ! conventional dendritic cell is_a: CL:0002320 ! connective tissue cell intersection_of: CL:0000990 ! conventional dendritic cell -intersection_of: lacks_plasma_membrane_part PR:000001813 ! adhesion G protein-coupled receptor E1 +intersection_of: CL:4030046 PR:000001813 ! lacks_plasma_membrane_part adhesion G protein-coupled receptor E1 intersection_of: part_of UBERON:0001013 ! adipose tissue +relationship: CL:4030046 PR:000001813 ! lacks_plasma_membrane_part adhesion G protein-coupled receptor E1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002010 ! pre-conventional dendritic cell -relationship: lacks_plasma_membrane_part PR:000001813 ! adhesion G protein-coupled receptor E1 relationship: part_of UBERON:0001013 ! adipose tissue creation_date: 2010-11-23T01:38:21Z @@ -31421,9 +20472,9 @@ def: "An adipose dendritic cell that is SIRPa-negative." [GOC:tfm, http://www.im synonym: "DC.SIRPa-.Ad" EXACT [] is_a: CL:0002462 ! adipose dendritic cell intersection_of: CL:0000990 ! conventional dendritic cell -intersection_of: lacks_plasma_membrane_part PR:000001968 ! tyrosine-protein phosphatase non-receptor type substrate 1 +intersection_of: CL:4030046 PR:000001968 ! lacks_plasma_membrane_part tyrosine-protein phosphatase non-receptor type substrate 1 +relationship: CL:4030046 PR:000001968 ! lacks_plasma_membrane_part tyrosine-protein phosphatase non-receptor type substrate 1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001968 ! tyrosine-protein phosphatase non-receptor type substrate 1 creation_date: 2010-11-23T01:40:46Z [Term] @@ -31444,12 +20495,12 @@ def: "A CD11b-positive dendritic cell located in the serosal portion of the smal synonym: "DC.11cloSer.SI" EXACT [] is_a: CL:0002465 {is_inferred="true"} ! CD11b-positive dendritic cell intersection_of: CL:0002465 ! CD11b-positive dendritic cell -intersection_of: lacks_plasma_membrane_part PR:000001010 ! integrin alpha-E +intersection_of: CL:4030046 PR:000001010 ! lacks_plasma_membrane_part integrin alpha-E intersection_of: RO:0002104 GO:0042613 ! has plasma membrane part MHC class II protein complex intersection_of: RO:0002104 PR:000001006 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C intersection_of: RO:0015016 PR:000001013 ! has low plasma membrane amount integrin alpha-X +relationship: CL:4030046 PR:000001010 ! lacks_plasma_membrane_part integrin alpha-E relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001010 ! integrin alpha-E relationship: RO:0002104 GO:0042613 ! has plasma membrane part MHC class II protein complex relationship: RO:0002104 PR:000001006 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C relationship: RO:0015016 PR:000001013 ! has low plasma membrane amount integrin alpha-X @@ -31462,10 +20513,10 @@ def: "A myeloid suppressor cell that is Gr1-high and CD11c-negative." [GOC:tfm, synonym: "MDS.Gr1hi" EXACT [] is_a: CL:0000889 {is_inferred="true"} ! myeloid suppressor cell intersection_of: CL:0000889 ! myeloid suppressor cell -intersection_of: lacks_plasma_membrane_part PR:000001013 ! integrin alpha-X +intersection_of: CL:4030046 PR:000001013 ! lacks_plasma_membrane_part integrin alpha-X intersection_of: RO:0015015 PR:000002980 ! has high plasma membrane amount lymphocyte antigen 6C2 +relationship: CL:4030046 PR:000001013 ! lacks_plasma_membrane_part integrin alpha-X relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001013 ! integrin alpha-X relationship: RO:0015015 PR:000002980 ! has high plasma membrane amount lymphocyte antigen 6C2 creation_date: 2010-11-23T02:15:12Z @@ -31490,9 +20541,9 @@ def: "Gr1-high monocyte that lacks MHC-II receptor complex." [GOC:tfm, http://ww synonym: "Mo.6C+II-" EXACT [] is_a: CL:0002395 {is_inferred="true"} ! Gr1-high classical monocyte intersection_of: CL:0002395 ! Gr1-high classical monocyte -intersection_of: lacks_plasma_membrane_part GO:0042613 ! MHC class II protein complex +intersection_of: CL:4030046 GO:0042613 ! lacks_plasma_membrane_part MHC class II protein complex +relationship: CL:4030046 GO:0042613 ! lacks_plasma_membrane_part MHC class II protein complex relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part GO:0042613 ! MHC class II protein complex creation_date: 2010-11-23T03:27:12Z [Term] @@ -31514,9 +20565,9 @@ def: "Gr1-low non-classical monocyte that lacks expression of a MHC-II complex." synonym: "Mo.6C-II-" EXACT [] is_a: CL:0002058 {is_inferred="true"} ! Gr1-low non-classical monocyte intersection_of: CL:0002058 ! Gr1-low non-classical monocyte -intersection_of: lacks_plasma_membrane_part GO:0042613 ! MHC class II protein complex +intersection_of: CL:4030046 GO:0042613 ! lacks_plasma_membrane_part MHC class II protein complex +relationship: CL:4030046 GO:0042613 ! lacks_plasma_membrane_part MHC class II protein complex relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part GO:0042613 ! MHC class II protein complex creation_date: 2010-11-23T03:38:15Z [Term] @@ -31549,11 +20600,11 @@ name: lymphoid MHC-II-negative classical monocyte def: "A MHC-II-negative classical monocyte located in lymphoid tissue that is F4/80-positive, CD11c-negative, and CD11b-high." [GOC:tfm, http://www.immgen.org/index_content.html] is_a: CL:0002469 {is_inferred="true"} ! MHC-II-negative classical monocyte intersection_of: CL:0002469 ! MHC-II-negative classical monocyte -intersection_of: lacks_plasma_membrane_part PR:000001013 ! integrin alpha-X +intersection_of: CL:4030046 PR:000001013 ! lacks_plasma_membrane_part integrin alpha-X intersection_of: RO:0002104 PR:000001813 ! has plasma membrane part adhesion G protein-coupled receptor E1 intersection_of: RO:0015015 PR:000001012 ! has high plasma membrane amount integrin alpha-M +relationship: CL:4030046 PR:000001013 ! lacks_plasma_membrane_part integrin alpha-X relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001013 ! integrin alpha-X relationship: RO:0002104 PR:000001813 ! has plasma membrane part adhesion G protein-coupled receptor E1 relationship: RO:0015015 PR:000001012 ! has high plasma membrane amount integrin alpha-M creation_date: 2010-11-23T04:00:52Z @@ -31584,15 +20635,15 @@ is_a: CL:0000864 {is_inferred="true"} ! tissue-resident macrophage is_a: CL:1001610 ! bone marrow hematopoietic cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000864 ! tissue-resident macrophage -intersection_of: lacks_plasma_membrane_part PR:000001014 ! receptor-type tyrosine-protein phosphatase C isoform CD45RABC -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000002980 ! lymphocyte antigen 6C2 +intersection_of: CL:4030046 PR:000001014 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RABC +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000002980 ! lacks_plasma_membrane_part lymphocyte antigen 6C2 intersection_of: RO:0002104 PR:000001813 ! has plasma membrane part adhesion G protein-coupled receptor E1 intersection_of: RO:0002104 PR:000002062 ! has plasma membrane part macrophage colony-stimulating factor 1 receptor +relationship: CL:4030046 PR:000001014 ! lacks_plasma_membrane_part receptor-type tyrosine-protein phosphatase C isoform CD45RABC +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000002980 ! lacks_plasma_membrane_part lymphocyte antigen 6C2 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001014 ! receptor-type tyrosine-protein phosphatase C isoform CD45RABC -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000002980 ! lymphocyte antigen 6C2 relationship: RO:0002104 PR:000001813 ! has plasma membrane part adhesion G protein-coupled receptor E1 relationship: RO:0002104 PR:000002062 ! has plasma membrane part macrophage colony-stimulating factor 1 receptor creation_date: 2010-11-23T04:19:25Z @@ -31621,10 +20672,10 @@ def: "An adipose macrophage that does not express F4/80but is MHC-II-positive. T synonym: "MF.Autofl.Ad" EXACT [] is_a: CL:0002477 {is_inferred="true"} ! adipose macrophage intersection_of: CL:0002477 ! adipose macrophage -intersection_of: lacks_plasma_membrane_part PR:000001813 ! adhesion G protein-coupled receptor E1 +intersection_of: CL:4030046 PR:000001813 ! lacks_plasma_membrane_part adhesion G protein-coupled receptor E1 intersection_of: RO:0002104 GO:0042613 ! has plasma membrane part MHC class II protein complex +relationship: CL:4030046 PR:000001813 ! lacks_plasma_membrane_part adhesion G protein-coupled receptor E1 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001813 ! adhesion G protein-coupled receptor E1 relationship: RO:0002104 GO:0042613 ! has plasma membrane part MHC class II protein complex creation_date: 2010-11-23T04:40:50Z @@ -31635,10 +20686,10 @@ def: "An adipose macrophage that does not express MHC-II but is F4/80-positive." synonym: "MF.F480+.Ad" EXACT [] is_a: CL:0002477 {is_inferred="true"} ! adipose macrophage intersection_of: CL:0002477 ! adipose macrophage -intersection_of: lacks_plasma_membrane_part GO:0042613 ! MHC class II protein complex +intersection_of: CL:4030046 GO:0042613 ! lacks_plasma_membrane_part MHC class II protein complex intersection_of: RO:0002104 PR:000001813 ! has plasma membrane part adhesion G protein-coupled receptor E1 +relationship: CL:4030046 GO:0042613 ! lacks_plasma_membrane_part MHC class II protein complex relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part GO:0042613 ! MHC class II protein complex relationship: RO:0002104 PR:000001813 ! has plasma membrane part adhesion G protein-coupled receptor E1 creation_date: 2010-11-23T04:35:53Z @@ -31736,7 +20787,6 @@ id: CL:0002488 name: trophoblast giant cell def: "A trophoblast cell that has a large volume of cytoplasm, is polyploid and is usually mononuclear but is also occasionally multi-nucleate. This cell type is important in establishing maternal physiology and remodeling of the vasculature of the placenta." [GOC:tfm, MP:0001714, MP:19876834] synonym: "giant trophoblast cell" EXACT [] -is_a: BFO:0000040 ! material entity is_a: CL:0000351 {is_inferred="true"} ! trophoblast cell intersection_of: CL:0000351 ! trophoblast cell intersection_of: bearer_of PATO:0000586 ! increased size @@ -31755,11 +20805,11 @@ synonym: "CD4-CD8- T cell" EXACT [MP:0002407] synonym: "double negative T cell" EXACT [] is_a: CL:0000893 ! thymocyte intersection_of: CL:0000893 ! thymocyte -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000025402 ! T cell receptor co-receptor CD8 +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000025402 ! lacks_plasma_membrane_part T cell receptor co-receptor CD8 +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000025402 ! lacks_plasma_membrane_part T cell receptor co-receptor CD8 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000025402 ! T cell receptor co-receptor CD8 creation_date: 2010-12-06T03:03:38Z [Term] @@ -31812,7 +20862,6 @@ xref: BTO:0001539 xref: CALOHA:TS-0115 xref: FMA:83808 xref: FMA:84791 -is_a: BFO:0000004 ! independent continuant is_a: CL:0000548 ! animal cell is_a: CL:0002371 {is_inferred="true"} ! somatic cell intersection_of: CL:0002371 ! somatic cell @@ -31936,13 +20985,13 @@ def: "A CD11b-positive dendritic cell that is CD11b-high, CD45-positive, MHC-II- synonym: "DC.103-11b+.Lv" EXACT [] is_a: CL:0002454 {is_inferred="true"} ! Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell intersection_of: CL:0002454 ! Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell -intersection_of: lacks_plasma_membrane_part PR:000001010 ! integrin alpha-E +intersection_of: CL:4030046 PR:000001010 ! lacks_plasma_membrane_part integrin alpha-E intersection_of: located_in UBERON:0001281 ! hepatic sinusoid intersection_of: RO:0002104 GO:0042613 ! has plasma membrane part MHC class II protein complex intersection_of: RO:0002104 PR:000001006 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C intersection_of: RO:0015015 PR:000001012 ! has high plasma membrane amount integrin alpha-M +relationship: CL:4030046 PR:000001010 ! lacks_plasma_membrane_part integrin alpha-E relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001010 ! integrin alpha-E relationship: located_in UBERON:0001281 ! hepatic sinusoid relationship: RO:0002104 GO:0042613 ! has plasma membrane part MHC class II protein complex relationship: RO:0002104 PR:000001006 ! has plasma membrane part receptor-type tyrosine-protein phosphatase C @@ -31975,13 +21024,13 @@ name: langerin-positive lymph node dendritic cell def: "A dermal dendritic cell isolated from skin draining lymph nodes that is langerin-positive, MHC-II-positive, and CD4-negative and CD8a-negative." [GOC:tfm, http://www.immgen.org/index_content.html] is_a: CL:0000990 {is_inferred="true"} ! conventional dendritic cell intersection_of: CL:0000990 ! conventional dendritic cell -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: RO:0002104 GO:0042613 ! has plasma membrane part MHC class II protein complex intersection_of: RO:0002104 PR:000001293 ! has plasma membrane part C-type lectin domain family 4 member K +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain relationship: RO:0002104 GO:0042613 ! has plasma membrane part MHC class II protein complex relationship: RO:0002104 PR:000001293 ! has plasma membrane part C-type lectin domain family 4 member K creation_date: 2011-01-21T01:57:00Z @@ -31992,16 +21041,16 @@ name: langerin-negative, CD103-negative lymph node dendritic cell def: "A dermal dendritic cell isolated from skin draining lymph nodes that is langerin-negative, MHC-II-positive, and CD4-negative and CD8a-negative." [GOC:tfm, http://www.immgen.org/index_content.html] is_a: CL:0000990 {is_inferred="true"} ! conventional dendritic cell intersection_of: CL:0000990 ! conventional dendritic cell -intersection_of: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -intersection_of: lacks_plasma_membrane_part PR:000001010 ! integrin alpha-E -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001293 ! C-type lectin domain family 4 member K +intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +intersection_of: CL:4030046 PR:000001010 ! lacks_plasma_membrane_part integrin alpha-E +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001293 ! lacks_plasma_membrane_part C-type lectin domain family 4 member K intersection_of: RO:0002104 GO:0042613 ! has plasma membrane part MHC class II protein complex +relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule +relationship: CL:4030046 PR:000001010 ! lacks_plasma_membrane_part integrin alpha-E +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001293 ! lacks_plasma_membrane_part C-type lectin domain family 4 member K relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001004 ! CD4 molecule -relationship: lacks_plasma_membrane_part PR:000001010 ! integrin alpha-E -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001293 ! C-type lectin domain family 4 member K relationship: RO:0002104 GO:0042613 ! has plasma membrane part MHC class II protein complex creation_date: 2011-01-21T02:13:58Z @@ -32026,10 +21075,10 @@ def: "A langerin-positive lymph node dendritic cell that is CD103-negative and C is_a: CL:0002454 ! Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell is_a: CL:0002507 {is_inferred="true"} ! langerin-positive lymph node dendritic cell intersection_of: CL:0002507 ! langerin-positive lymph node dendritic cell -intersection_of: lacks_plasma_membrane_part PR:000001010 ! integrin alpha-E +intersection_of: CL:4030046 PR:000001010 ! lacks_plasma_membrane_part integrin alpha-E intersection_of: RO:0015015 PR:000001012 ! has high plasma membrane amount integrin alpha-M +relationship: CL:4030046 PR:000001010 ! lacks_plasma_membrane_part integrin alpha-E relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part PR:000001010 ! integrin alpha-E relationship: RO:0015015 PR:000001012 ! has high plasma membrane amount integrin alpha-M creation_date: 2011-01-21T02:11:14Z @@ -32201,10 +21250,10 @@ synonym: "CD14+ dermal DC" EXACT [] is_a: CL:0001006 {is_inferred="true"} ! dermal dendritic cell intersection_of: CL:0001006 ! dermal dendritic cell intersection_of: capable_of GO:0045191 ! regulation of isotype switching -intersection_of: lacks_plasma_membrane_part PR:000002025 ! T-cell surface glycoprotein CD1a +intersection_of: CL:4030046 PR:000002025 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD1a intersection_of: RO:0002104 PR:000001889 ! has plasma membrane part CD14 molecule relationship: capable_of GO:0045191 ! regulation of isotype switching -relationship: lacks_plasma_membrane_part PR:000002025 ! T-cell surface glycoprotein CD1a +relationship: CL:4030046 PR:000002025 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD1a relationship: RO:0002104 PR:000001889 ! has plasma membrane part CD14 molecule [Term] @@ -32586,7 +21635,6 @@ creation_date: 2011-02-28T05:24:28Z id: CL:0002559 name: hair follicle cell def: "An animal cell that is part of a hair follicle." [GOC:tfm] -is_a: BFO:0000004 ! independent continuant is_a: CL:0002371 {is_inferred="true"} ! somatic cell intersection_of: CL:0002371 ! somatic cell intersection_of: part_of UBERON:0002073 ! hair follicle @@ -33909,25 +22957,25 @@ is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000542 {is_inferred="true"} ! lymphocyte is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000542 ! lymphocyte -intersection_of: lacks_plasma_membrane_part GO:0042105 ! alpha-beta T cell receptor complex -intersection_of: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -intersection_of: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -intersection_of: lacks_plasma_membrane_part PR:000001013 ! integrin alpha-X -intersection_of: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -intersection_of: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -intersection_of: lacks_plasma_membrane_part PR:000001874 ! KLRB1-like protein -intersection_of: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) +intersection_of: CL:4030046 GO:0042105 ! lacks_plasma_membrane_part alpha-beta T cell receptor complex +intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +intersection_of: CL:4030046 PR:000001013 ! lacks_plasma_membrane_part integrin alpha-X +intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +intersection_of: CL:4030046 PR:000001874 ! lacks_plasma_membrane_part KLRB1-like protein +intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor intersection_of: RO:0002104 PR:000002979 ! has plasma membrane part lymphocyte antigen 6A-2/6E-1 +relationship: CL:4030046 GO:0042105 ! lacks_plasma_membrane_part alpha-beta T cell receptor complex +relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule +relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M +relationship: CL:4030046 PR:000001013 ! lacks_plasma_membrane_part integrin alpha-X +relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon +relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain +relationship: CL:4030046 PR:000001874 ! lacks_plasma_membrane_part KLRB1-like protein +relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -relationship: lacks_plasma_membrane_part GO:0042105 ! alpha-beta T cell receptor complex -relationship: lacks_plasma_membrane_part PR:000001002 ! CD19 molecule -relationship: lacks_plasma_membrane_part PR:000001012 ! integrin alpha-M -relationship: lacks_plasma_membrane_part PR:000001013 ! integrin alpha-X -relationship: lacks_plasma_membrane_part PR:000001020 ! CD3 epsilon -relationship: lacks_plasma_membrane_part PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain -relationship: lacks_plasma_membrane_part PR:000001874 ! KLRB1-like protein -relationship: lacks_plasma_membrane_part PR:000002981 ! lymphocyte antigen 76 (mouse) relationship: RO:0002104 PR:000002065 ! has plasma membrane part mast/stem cell growth factor receptor relationship: RO:0002104 PR:000002979 ! has plasma membrane part lymphocyte antigen 6A-2/6E-1 creation_date: 2011-08-29T10:08:02Z @@ -34462,6 +23510,11 @@ id: CL:0003048 name: L cone cell namespace: cell def: "A cone cell that detects long wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 564-580 nm." [WikipediaVersioned:Cone_cell&oldid=1111888680] +synonym: "L cone" EXACT [PMID:32555229] +synonym: "L-cone" EXACT [PMID:29603924] +synonym: "long wavelength sensitive cone" EXACT [PMID:31117170] +synonym: "long- (L) wavelength-sensitive cone" EXACT [https://doi.org/10.7554/eLife.39166] +synonym: "long-wavelength cone" EXACT [https://doi.org/10.1038/323623a0] is_a: CL:0000573 ! retinal cone cell is_a: PR:000050567 ! protein-containing material entity relationship: has_part PR:000001244 ! long-wave-sensitive opsin 1 @@ -34472,6 +23525,11 @@ id: CL:0003049 name: M cone cell namespace: cell def: "A cone cell that detects medium wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 534-545 nm." [WikipediaVersioned:Cone_cell&oldid=1111888680] +synonym: "M cone" EXACT [PMID:32555229] +synonym: "M-cone" EXACT [PMID:29603924] +synonym: "middle wavelength sensitive cone" EXACT [PMID:31117170] +synonym: "middle- (M) wavelength-sensitive cone" EXACT [https://doi.org/10.7554/eLife.39166] +synonym: "middle-wavelength-sensitive (M) cone" EXACT [https://opg.optica.org/josaa/abstract.cfm?URI=josaa-6-1-153] is_a: CL:0000573 ! retinal cone cell is_a: PR:000050567 ! protein-containing material entity relationship: has_part PR:000001224 ! medium-wave-sensitive opsin @@ -34482,6 +23540,14 @@ id: CL:0003050 name: S cone cell namespace: cell def: "A cone cell that detects short wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 420-440 nm." [WikipediaVersioned:Cone_cell&oldid=1111888680] +synonym: "S cone" EXACT [PMID:32555229] +synonym: "S-(short-wavelength sensitive) cone" EXACT [PMID:31117170] +synonym: "S-cone" EXACT [PMID:32555229] +synonym: "S-cone photoreceptor" EXACT [https://doi.org/10.7554/eLife.39166] +synonym: "short wavelength sensitive cone" EXACT [PMID:31117170] +synonym: "short- (S) wavelength-sensitive cone" EXACT [https://doi.org/10.7554/eLife.39166] +synonym: "short-wavelength sensitive cone" EXACT [PMID:31117170] +synonym: "short-wavelength-sensitive (S) cone" EXACT [https://opg.optica.org/josaa/abstract.cfm?URI=josaa-6-1-153] is_a: CL:0000573 ! retinal cone cell property_value: dc-contributor "https://orcid.org/0000-0002-5260-9315" xsd:string @@ -34716,7 +23782,7 @@ namespace: cell def: "A horizontal cell with a large cell body, thick dendrites, and a large dendritic arbor." [PMID:8571130] synonym: "A Horizontal Cell" EXACT [] is_a: CL:0000745 ! retina horizontal cell -relationship: lacks_part GO:0030424 ! axon +relationship: CL:4030045 GO:0030424 ! lacks_part axon property_value: dc-contributor "https://orcid.org/0000-0001-7258-9596" xsd:string property_value: dc-contributor "https://orcid.org/0000-0002-5260-9315" xsd:string @@ -35220,7 +24286,6 @@ def: "A cuboidal epithelial cell of the kidney which secretes acid and reabsorbs comment: Type A intercalated cells are the more abundant type of intercalated cell in the outer stripe of the outer medulla in most mammalian species. {xref="PMID:25632105"} synonym: "type A intercalated cell" EXACT [PMID:25632105] synonym: "type A-IC" EXACT [PMID:25632105] -is_a: BFO:0000040 ! material entity is_a: CL:0005010 ! renal intercalated cell relationship: capable_of GO:0046717 ! acid secretion @@ -35558,7 +24623,6 @@ id: CL:0007018 name: epidermal ciliary cell def: "Ciliated cell of the embryonic epidermis and functions in embryonic movements." [PMCID:PMC3046089] comment: Taxon specificity not clear -present in embryonic anurans. -is_a: BFO:0000004 ! independent continuant is_a: CL:0000064 ! ciliated cell is_a: CL:0002321 ! embryonic cell (metazoa) relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 @@ -35595,7 +24659,6 @@ id: CL:0007022 name: micropylar cell def: "A specialized pore forming cell of the follicle, located adjacent to the animal pole of the oocyte. The micropylar cell makes the single micropyle (pore) through the chorion through which the sperm fertilizes the egg." [PMID:18582455, ZFA:0005239] synonym: "plug cell" EXACT [] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000548 ! animal cell relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 relationship: part_of UBERON:0001305 ! ovarian follicle @@ -35604,7 +24667,6 @@ relationship: part_of UBERON:0001305 ! ovarian follicle id: CL:0007023 name: flask cell def: "Epidermal cell rich in mitochondria. In amphibians, appears during metamorphosis." [DOI:10.1007/BF00717048] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000003 ! native cell relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 relationship: part_of UBERON:0001003 ! skin epidermis @@ -35674,9 +24736,12 @@ is_a: CL:0008018 ! somatic muscle myoblast [Term] id: CL:0008007 name: visceral muscle cell -def: "A muscle cell that is part of some visceral muscle" [GOC:dos] +def: "A muscle cell that is part of some visceral muscle." [GOC:dos] xref: FBbt:00005070 is_a: CL:0000187 ! muscle cell +intersection_of: CL:0000187 ! muscle cell +intersection_of: part_of UBERON:8600004 ! visceral muscle tissue +relationship: part_of UBERON:8600004 ! visceral muscle tissue [Term] id: CL:0008008 @@ -35823,10 +24888,10 @@ id: CL:0008024 name: pancreatic endocrine cell def: "An endocrine cell that is part of the pancreas." [GOC:dos] subset: human_reference_atlas -is_a: CL:0000163 ! endocrine cell +is_a: CL:0000083 ! epithelial cell of pancreas +is_a: CL:0000164 ! enteroendocrine cell intersection_of: CL:0000163 ! endocrine cell intersection_of: part_of UBERON:0001264 ! pancreas -relationship: part_of UBERON:0001264 ! pancreas relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] @@ -36059,7 +25124,6 @@ name: compound eye retinal cell def: "Any cell in the compound eye, a light sensing organ composed of ommatidia." [] xref: GOC:pr xref: PMID:12021768 -is_a: BFO:0000004 ! independent continuant is_a: CL:0002371 ! somatic cell [Term] @@ -36068,7 +25132,6 @@ name: inflammatory cell def: "Any cell participating in the inflammatory response to a foreign substance, e.g. neutrophil, macrophage." [] xref: GOC:pr xref: http://en.wikipedia.org/wiki/Inflammatory_response -is_a: BFO:0000040 ! material entity is_a: CL:0002371 ! somatic cell relationship: capable_of_part_of GO:0006954 ! inflammatory response @@ -36078,7 +25141,6 @@ name: larval midgut cell def: "Any cell in the midgut (middle subdivision of a digestive tract) of an insect larva." [] xref: GOC:pr xref: http://en.wikipedia.org/wiki/Insect#Midgut -is_a: BFO:0000004 ! independent continuant is_a: CL:0002371 ! somatic cell relationship: in_taxon NCBITaxon:50557 ! Insecta relationship: part_of UBERON:0001555 ! digestive tract @@ -36101,7 +25163,6 @@ name: salivary gland cell def: "Any cell in a salivary gland." [] xref: GOC:pr xref: http://en.wikipedia.org/wiki/Salivary_gland -is_a: BFO:0000004 ! independent continuant is_a: CL:0002371 ! somatic cell relationship: part_of UBERON:0001044 ! saliva-secreting gland @@ -36240,7 +25301,6 @@ id: CL:0009015 name: Peyer's patch follicular dendritic cell def: "A follicular dendritic cell located in the Peyer's patch. These cells from a meshwork in which Peyer's patch B cells reside." [https://orcid.org/0000-0003-4183-8865, PMID:24437401] subset: location_grouping -is_a: BFO:0000004 ! independent continuant is_a: CL:0000442 ! follicular dendritic cell intersection_of: CL:0000442 ! follicular dendritic cell intersection_of: part_of UBERON:0001211 ! Peyer's patch @@ -37359,7 +26419,6 @@ name: lymph node marginal reticular cell def: "A fibroblastic reticular cell found in the lymph node subcapsular sinus." [https://orcid.org/0000-0001-7655-4833, PMID:21435450, PMID:22566825, PMID:25998961, PMID:28262465, PMID:29752062, PMID:34256989] subset: human_reference_atlas synonym: "marginal reticular cell" BROAD [] -is_a: BFO:0000040 ! material entity is_a: CL:0009102 ! lymph node fibroblastic reticular cell relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: located_in UBERON:0005463 ! subcapsular sinus of lymph node @@ -37609,7 +26668,6 @@ intersection_of: part_of UBERON:0000948 ! heart [Term] id: CL:0010007 name: His-Purkinje system cell -is_a: BFO:0000004 ! independent continuant is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: part_of UBERON:0004146 ! His-Purkinje system @@ -37943,6 +27001,7 @@ comment: Mast cells do not normally express CD25, but neoplastic mast cells may synonym: "CD25+ neoplastic mast cell" EXACT [] is_a: CARO:0000006 ! material anatomical entity is_a: CL:0001063 ! neoplastic cell +is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0001063 ! neoplastic cell intersection_of: RO:0001000 CL:0000097 ! derives from mast cell intersection_of: RO:0002104 PR:000001380 ! has plasma membrane part interleukin-2 receptor subunit alpha @@ -38150,14 +27209,12 @@ relationship: capable_of GO:0061538 ! histamine secretion, neurotransmission [Term] id: CL:0011111 -name: gonadotropin releasing neuron -def: "Neuroendocrine cells that are born in the nasal placode during embryonic development and migrate through the nose and forebrain to the hypothalamus, where they regulate reproduction." [GOC:NV, PMID:21828096] +name: gonadotropin-releasing hormone neuron +def: "A neuroendocrine cell that secretes gonadotropin-releasing hormone (GnRH). A GnRH neuron is born in the nasal placode during embryonic development and migrates through the nose and forebrain to the hypothalamus. This cell regulates reproduction by secreting GnRH into the pituitary portal vessels to induce the release of gonadotropins into the general circulation." [GOC:NV, PMID:21828096] synonym: "GnRH neuron" EXACT [] synonym: "GnRH-secreting neuron" EXACT [] is_a: CL:0000165 ! neuroendocrine cell -intersection_of: CL:0000540 ! neuron -intersection_of: capable_of GO:0032274 ! gonadotropin secretion -relationship: capable_of GO:0032274 ! gonadotropin secretion +relationship: RO:0002596 GO:0032274 ! capable of regulating gonadotropin secretion [Term] id: CL:0011112 @@ -38189,7 +27246,6 @@ id: CL:0011115 name: precursor cell def: "A cell that, by division or terminal differentiation, can give rise to other cell types." [GOC:dos] comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. -is_a: BFO:0000040 ! material entity is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: capable_of GO:0030154 ! cell differentiation @@ -38756,7 +27812,6 @@ id: CL:1000147 name: cardiac valve cell def: "A cell that is part of a cardiac valve." [PMID:25311230] synonym: "heart valve cell" EXACT [PMID:30796046] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: part_of UBERON:0000946 ! cardiac valve @@ -38774,7 +27829,6 @@ relationship: part_of UBERON:0001054 ! Malpighian tubule [Term] id: CL:1000182 name: malpighian tubule tip cell -is_a: BFO:0000004 ! independent continuant is_a: CL:0000423 ! tip cell intersection_of: CL:0000423 ! tip cell intersection_of: part_of UBERON:0001054 ! Malpighian tubule @@ -38802,8 +27856,9 @@ relationship: part_of UBERON:0004129 ! growth plate cartilage [Term] id: CL:1000222 name: stomach neuroendocrine cell +is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000165 ! neuroendocrine cell -is_a: CL:0002178 ! epithelial cell of stomach +is_a: CL:0002659 ! glandular cell of stomach intersection_of: CL:0000165 ! neuroendocrine cell intersection_of: part_of UBERON:0000945 ! stomach @@ -39520,7 +28575,6 @@ name: paneth cell of epithelium of crypt of Lieberkuhn of small intestine def: "A paneth cell that is part of the epithelium of crypt of Lieberkuhn of small intestine." [GOC:tfm] xref: FMA:263108 is_a: CL:1000343 ! paneth cell of epithelium of small intestine -relationship: part_of UBERON:0001983 ! crypt of Lieberkuhn [Term] id: CL:1000346 @@ -39808,6 +28862,7 @@ name: myocardial endocrine cell of septal division of left branch of atrioventri def: "A myocardial endocrine cell that is part of the septal division of left branch of atrioventricular bundle." [GOC:tfm] xref: FMA:263180 is_a: CL:0002074 ! myocardial endocrine cell +is_a: CL:0008009 ! transversely striated visceral muscle cell is_a: CL:0010007 ! His-Purkinje system cell is_a: CL:2000046 ! ventricular cardiac muscle cell relationship: part_of UBERON:0005986 ! left bundle branch @@ -39987,6 +29042,7 @@ synonym: "sinoatrial node myocyte" EXACT [] synonym: "sinuatrial node myocyte" EXACT [FMA:67102] xref: FMA:67102 is_a: CL:0002072 ! nodal myocyte +is_a: CL:0008009 ! transversely striated visceral muscle cell intersection_of: CL:0000187 ! muscle cell intersection_of: part_of UBERON:0002351 ! sinoatrial node relationship: part_of UBERON:0002351 ! sinoatrial node @@ -40002,6 +29058,7 @@ synonym: "AV node cardiac muscle cell" EXACT [GOC:pr] synonym: "AV node cell" EXACT [GOC:pr] xref: FMA:67106 is_a: CL:0002072 ! nodal myocyte +is_a: CL:0008009 ! transversely striated visceral muscle cell is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0000187 ! muscle cell intersection_of: part_of UBERON:0002352 ! atrioventricular node @@ -40549,6 +29606,7 @@ def: "A transitional myocyte that is part of the atrioventricular bundle." [GOC: xref: FMA:83388 xref: FMA:83885 is_a: CL:0002073 {is_inferred="true"} ! transitional myocyte +is_a: CL:0008009 ! transversely striated visceral muscle cell is_a: CL:0010005 ! atrioventricular bundle cell is_a: CL:2000046 ! ventricular cardiac muscle cell intersection_of: CL:0002073 ! transitional myocyte @@ -40581,6 +29639,7 @@ name: Purkinje myocyte of atrioventricular bundle def: "A Purkinje myocyte that is part of the atrioventricular bundle." [GOC:tfm] xref: FMA:83393 is_a: CL:0002068 {is_inferred="true"} ! Purkinje myocyte +is_a: CL:0008009 ! transversely striated visceral muscle cell is_a: CL:0010005 ! atrioventricular bundle cell is_a: CL:2000046 ! ventricular cardiac muscle cell intersection_of: CL:0002068 ! Purkinje myocyte @@ -40615,7 +29674,6 @@ name: cholangiocyte def: "An epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. They are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts." [GOC:tfm, PMID:16550043, PMID:18356246] synonym: "epithelial cell of bile duct" EXACT [] xref: FMA:86481 -is_a: BFO:0000040 ! material entity is_a: CARO:0000000 ! anatomical entity is_a: CL:0000069 {is_inferred="true"} ! branched duct epithelial cell intersection_of: CL:0000069 ! branched duct epithelial cell @@ -40713,7 +29771,6 @@ intersection_of: part_of UBERON:0002108 ! small intestine id: CL:1000497 name: kidney cell xref: KUPO:0001010 -is_a: BFO:0000004 ! independent continuant is_a: CL:0000548 {is_inferred="true"} ! animal cell is_a: CL:0002371 ! somatic cell intersection_of: CL:0000548 ! animal cell @@ -40842,7 +29899,6 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:1000600 name: lower urinary tract cell xref: KUPO:0001115 -is_a: BFO:0000004 ! independent continuant is_a: CL:0000548 {is_inferred="true"} ! animal cell intersection_of: CL:0000548 ! animal cell intersection_of: part_of UBERON:0001556 ! lower urinary tract @@ -40852,7 +29908,6 @@ relationship: part_of UBERON:0001556 ! lower urinary tract id: CL:1000601 name: ureteral cell xref: KUPO:0001116 -is_a: BFO:0000004 ! independent continuant is_a: CL:0000548 {is_inferred="true"} ! animal cell intersection_of: CL:0000548 ! animal cell intersection_of: part_of UBERON:0000056 ! ureter @@ -42505,7 +31560,6 @@ creation_date: 2014-02-20T23:06:41Z id: CL:2000004 name: pituitary gland cell def: "Any cell that is part of a pituitary gland." [GOC:TermGenie] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: part_of UBERON:0000007 ! pituitary gland @@ -42684,7 +31738,6 @@ creation_date: 2014-06-24T23:16:45Z id: CL:2000020 name: inner cell mass cell def: "Any native cell that is part of a inner cell mass." [GOC:TermGenie] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: part_of UBERON:0000087 ! inner cell mass @@ -42696,7 +31749,6 @@ creation_date: 2014-06-24T23:16:53Z id: CL:2000021 name: sebaceous gland cell def: "Any native cell that is part of a sebaceous gland." [GOC:TermGenie] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: part_of UBERON:0001821 ! sebaceous gland @@ -42708,7 +31760,6 @@ creation_date: 2014-06-24T23:17:00Z id: CL:2000022 name: cardiac septum cell def: "Any native cell that is part of a cardiac septum." [GOC:TermGenie] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: part_of UBERON:0002099 ! cardiac septum @@ -42796,7 +31847,6 @@ creation_date: 2014-06-25T01:17:43Z id: CL:2000030 name: hypothalamus cell def: "Any native cell that is part of a hypothalamus." [GOC:TermGenie] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: part_of UBERON:0001898 ! hypothalamus @@ -44507,7 +33557,6 @@ relationship: RO:0002292 PR:P09240 ! expresses cholecystokinin (mouse) id: CL:4023072 name: brain vascular cell def: "A cell that is part of the brain vasculature." [DOI:10.1101/2022.10.12.511898] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: part_of UBERON:0008998 ! vasculature of brain @@ -44518,7 +33567,6 @@ relationship: part_of UBERON:0008998 ! vasculature of brain id: CL:4023073 name: choroid plexus cell def: "A cell that is part of the choroid plexus." [DOI:10.1101/2022.10.12.511898] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: part_of UBERON:0001886 ! choroid plexus @@ -44591,8 +33639,8 @@ replaced_by: PCL:1000003 id: CL:4023079 name: midbrain-derived inhibitory neuron def: "A GABAergic inhibitory neuron that is derived from the midbrain." [DOI:10.1101/2022.10.12.511898] -is_a: CARO:0000000 ! anatomical entity is_a: CL:0000540 ! neuron +is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000540 ! neuron intersection_of: develops_from UBERON:0001891 ! midbrain relationship: dc-contributor http://orcid.org/0000-0001-7258-9596 @@ -45264,7 +34312,7 @@ property_value: dc-contributor "https://orcid.org/0000-0001-7655-4833" xsd:strin [Term] id: CL:4023189 name: parasol ganglion cell of retina -def: "A retinal ganglion cell ocated in the ganglion cell layer of the retina and projects to magnocellular cells in the lateral geniculate nucleus (LGN) as part of the magnocellular pathway in the visual system. They have large cell bodies as well as extensive branching dendrite networks and as such have large receptive fields." [PMID:32533915, WikipediaVersioned:Parasol_cell&oldid=1032171532] +def: "A retinal ganglion cell located in the ganglion cell layer of the retina. This cell projects to magnocellular cells in the lateral geniculate nucleus (LGN). They have large cell bodies and extensive, branching dendritic networks that contribute to their large receptive fields." [PMID:32533915, WikipediaVersioned:Parasol_cell&oldid=1032171532] comment: These cells should not be confused with M1-M14 retinal ganglion cells described in PMID:16626866 which refer to a different classification of retinal ganglion cells. synonym: "M cell" RELATED [] synonym: "M ganglion cell" RELATED [] @@ -45773,7 +34821,6 @@ property_value: seeAlso https://github.com/obophenotype/cell-ontology/pull/1725 id: CL:4030031 name: interstitial cell def: "Any cell that is located within the interstitium between the cells most prominent in defining a given tissue. \"Interstitial cell\" is a morphological term and refers to a variety of cells with differing origins and phenotypes." [PMID:24987007] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: part_of UBERON:0005169 ! interstitial tissue @@ -45817,7 +34864,6 @@ id: CL:4030034 name: respiratory ciliated cell def: "A ciliated cell of the respiratory system. Ciliated cells are present in airway epithelium." [PMID:18757316, PMID:21364219] synonym: "ciliated cell of the respiratory tract" EXACT [] -is_a: BFO:0000004 ! independent continuant is_a: CL:0000064 ! ciliated cell intersection_of: CL:0000064 ! ciliated cell intersection_of: part_of UBERON:0004802 ! respiratory tract epithelium @@ -45856,6 +34902,20 @@ relationship: develops_from CL:4030036 ! early spermatid relationship: part_of UBERON:0000079 ! male reproductive system property_value: dcterms-date "2023-02-01T14:02:15Z" xsd:dateTime +[Term] +id: CL:4030038 +name: CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell +def: "A CD24-positive, CD-133-positive, vimentin-positive cell found scattered throughout a renal proximal tubule and that may participate in tubular regeneration. Compared to other proximal tubular cell types, this cell contains less cytoplasm, fewer mitochondria and no brush border." [PMID:21281815, PMID:23124355] +comment: After acute tubular injury, this cell type becomes more numerous. In healthy rat kidneys, this cell is not detectable, whereas after unilateral ureteral obstruction (renal injury), it may appear de novo, arguing against the notion that this cell type represents a pre-existing progenitor cell population. In at least one study, data indicate that this cell type represents transiently dedifferentiated tubular cells involved in regeneration. {xref="PMID:23124355"} +synonym: "CD133+CD24+CD106- tubular cell" BROAD [https://doi.org/10.1002/stem.1130] +synonym: "CD24+CD133+ tubular cell" BROAD [PMID:23124355] +synonym: "CD24-positive tubular cell" BROAD [PMID:23124355] +is_a: CL:0002306 ! epithelial cell of proximal tubule +relationship: part_of UBERON:0008404 ! proximal tubular epithelium +relationship: RO:0002292 PR:000001786 ! expresses prominin-1 +relationship: RO:0002292 PR:000001932 ! expresses signal transducer CD24 +property_value: dcterms-date "2023-03-07T14:17:39Z" xsd:dateTime + [Term] id: CL:4030040 name: endometrial ciliated epithelial cell @@ -45941,7 +35001,7 @@ id: CL:4033002 name: neuroendocrine cell of epithelium of crypt of Lieberkuhn def: "A(n) neuroendocrine cell that is part of a(n) epithelium of crypt of Lieberkuhn." [PMID:31390635] is_a: CL:0000165 ! neuroendocrine cell -is_a: CL:0002563 ! intestinal epithelial cell +is_a: CL:1001516 ! intestinal enteroendocrine cell intersection_of: CL:0000165 ! neuroendocrine cell intersection_of: part_of UBERON:0011184 ! epithelium of crypt of Lieberkuhn relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 @@ -46077,6 +35137,145 @@ relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: part_of UBERON:0004804 ! oviduct epithelium property_value: dcterms-date "2023-02-02T15:07:12Z" xsd:dateTime +[Term] +id: CL:4033015 +name: retinal astrocyte +def: "A star-shaped glial cell that is part of some retina. This cell links neurons to blood vessels and may provide structural and physiological support to optic nerve head axons." [PMID:25236977, PMID:33796062] +comment: In response to elevated intraocular pressure, a retinal astrocyte may modulate extracellular matrix remodeling. In the human retina, a retinal astrocyte is GFAP-positive, SOD3-positive and GYPC-positive. {xref="PMID:33796062", xref="PMID:32555229"} +synonym: "retinal astroglia" RELATED [PMID:33796062] {synonymtypedef="PLURAL"} +is_a: CL:0000127 ! astrocyte +is_a: CL:0009004 ! retinal cell +intersection_of: CL:0000127 ! astrocyte +intersection_of: part_of UBERON:0000966 ! retina +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: part_of UBERON:0000966 ! retina +property_value: dcterms-date "2023-03-02T14:38:32Z" xsd:dateTime + +[Term] +id: CL:4033016 +name: secondary crest myofibroblast +def: "A myofibroblast that is part of an alveoli during alveolarization. The contractile force of this cell elongates the secondary crest, while producing a framework of elastin and tenascin. During the maturation of the septa, secondary crest myofibroblasts, together with matrix fibroblasts, secrete metalloproteinases and other ECM‐remodeling proteins to thin the septal tip ECM. The secondary crest myofibroblast continues producing elastin, eventually undergoing apoptosis during adulthood." [PMID:31331942, PMID:33624948] +synonym: "alveolar myofibroblast" RELATED [PMID:31331942] +synonym: "SCMF" RELATED abbreviation [PMID:33624948] +synonym: "SCMFs" RELATED PLURAL [PMID:25448080] +synonym: "secondary-crest myofibroblast" EXACT [PMID:31331942] +is_a: CL:0000186 ! myofibroblast cell +is_a: CL:0002320 ! connective tissue cell +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: dc-contributor https://orcid.org/0000-0002-9185-3994 +relationship: part_of UBERON:0000114 ! lung connective tissue +relationship: participates_in GO:0048286 ! lung alveolus development +property_value: dcterms-date "2023-03-16T09:17:47Z" xsd:dateTime + +[Term] +id: CL:4033017 +name: bronchiolar smooth muscle cell +def: "A smooth muscle cell that is part of a bronchiole." [ISBN:9781260462982, PMID:15347627] +is_a: CL:0019019 ! tracheobronchial smooth muscle cell +intersection_of: CL:0000192 ! smooth muscle cell +intersection_of: part_of UBERON:0002186 ! bronchiole +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: dc-contributor https://orcid.org/0000-0002-9185-3994 +relationship: part_of UBERON:0002186 ! bronchiole +property_value: dcterms-date "2023-03-16T09:38:17Z" xsd:dateTime + +[Term] +id: CL:4033018 +name: lung megakaryocyte +def: "A megakaryocyte that is resident in the lung connective tissue." [PMID:33351116] +synonym: "lung MKs" RELATED PLURAL [PMID:33351116] +is_a: CL:0000556 ! megakaryocyte +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: dc-contributor https://orcid.org/0000-0002-9185-3994 +property_value: dcterms-date "2023-03-16T11:31:23Z" xsd:dateTime + +[Term] +id: CL:4033020 +name: mucus secreting cell of trachea gland +def: "A mucus secreting cell that is part of a submucosal gland of the trachea." [PMID:18931053, PMID:29656943] +synonym: "tracheal submucosal gland mucous cell" EXACT [PMID:18931053] +is_a: CL:0000152 ! exocrine cell +is_a: CL:0000319 ! mucus secreting cell +intersection_of: CL:0000319 ! mucus secreting cell +intersection_of: part_of UBERON:0005203 ! trachea gland +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: dc-contributor https://orcid.org/0000-0002-9185-3994 +relationship: part_of UBERON:0005203 ! trachea gland +property_value: dcterms-date "2023-03-16T13:03:13Z" xsd:dateTime + +[Term] +id: CL:4033021 +name: myoepithelial cell of trachea gland +def: "A myoepithelial cell that is part of a submucosal gland of the trachea." [PMID:29656943] +is_a: CL:0000185 ! myoepithelial cell +is_a: CL:0000307 ! tracheal epithelial cell +is_a: CL:0002320 ! connective tissue cell +intersection_of: CL:0000185 ! myoepithelial cell +intersection_of: part_of UBERON:0005203 ! trachea gland +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: dc-contributor https://orcid.org/0000-0002-9185-3994 +relationship: part_of UBERON:0005203 ! trachea gland +property_value: dcterms-date "2023-03-16T13:36:43Z" xsd:dateTime + +[Term] +id: CL:4033022 +name: mucus secreting cell of bronchus submucosal gland +def: "A mucus secreting cell of a submucosal gland of the bronchus." [PMID:19965983] +synonym: "bronchial gland mucous cell" EXACT [PMID:5487122] +is_a: CL:0000152 ! exocrine cell +is_a: CL:0000319 ! mucus secreting cell +intersection_of: CL:0000319 ! mucus secreting cell +intersection_of: part_of UBERON:8410043 ! bronchus submucosal gland +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: dc-contributor https://orcid.org/0000-0002-9185-3994 +relationship: part_of UBERON:8410043 ! bronchus submucosal gland +property_value: dcterms-date "2023-03-16T15:12:52Z" xsd:dateTime + +[Term] +id: CL:4033023 +name: airway submucosal gland collecting duct epithelial cell +def: "An epithelial cell that is part of a collecting duct of an airway submucosal gland." [PMID:25648514, PMID:29656943] +is_a: CL:0000066 ! epithelial cell +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: dc-contributor https://orcid.org/0000-0002-9185-3994 +relationship: part_of UBERON:8410077 ! airway submucosal gland +property_value: dcterms-date "2023-03-16T15:20:28Z" xsd:dateTime + +[Term] +id: CL:4033024 +name: airway submucosal gland duct basal cell +def: "A basal cell that is part of a duct of an airway submucosal gland." [PMID:29656943, PMID:35046051] +is_a: CL:0000646 ! basal cell +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: part_of UBERON:8410077 ! airway submucosal gland +property_value: dc-contributor "https://orcid.org/0000-0002-9185-3994" xsd:string +property_value: dcterms-date "2023-03-16T15:51:39Z" xsd:dateTime + +[Term] +id: CL:4033025 +name: perichondrial fibroblast +def: "A fibroblast that is part of the fibrous layer of the perichondrium. This cell is responsible for collagen fiber production." [wikipedia:Perichondrium] +is_a: CL:0000057 ! fibroblast +intersection_of: CL:0000057 ! fibroblast +intersection_of: part_of UBERON:0008305 ! outer fibrous layer of perichondrium +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: dc-contributor https://orcid.org/0000-0002-9185-3994 +relationship: part_of UBERON:0008305 ! outer fibrous layer of perichondrium +property_value: dcterms-date "2023-03-16T16:12:50Z" xsd:dateTime + +[Term] +id: CL:4033026 +name: lung perichondrial fibroblast +def: "A perichondrial fibroblast that is part of the lung" [PMID:36543915] +synonym: "PC-fibro" RELATED abbreviation [PMID:36543915] +is_a: CL:0002553 ! fibroblast of lung +is_a: CL:4033025 ! perichondrial fibroblast +intersection_of: CL:4033025 ! perichondrial fibroblast +intersection_of: part_of UBERON:0002048 ! lung +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: dc-contributor https://orcid.org/0000-0002-9185-3994 +property_value: dcterms-date "2023-03-16T16:15:39Z" xsd:dateTime + [Term] id: CP:0000000 name: obsolete CP:0000000 @@ -46178,28 +35377,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006310 ! DNA recombination relationship: regulates GO:0006310 ! DNA recombination -[Term] -id: GO:0000035 -name: acyl binding -namespace: molecular_function -def: "Binding to an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid." [GOC:curators, ISBN:0198506732] -synonym: "acyl-CoA or acyl binding" BROAD [] -is_a: GO:0005488 ! binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:22221 ! acyl group -relationship: has_input CHEBI:22221 ! acyl group - -[Term] -id: GO:0000041 -name: transition metal ion transport -namespace: biological_process -def: "The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver." [ISBN:0198506732] -synonym: "transition metal transport" EXACT [] -is_a: GO:0030001 ! metal ion transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:33515 ! transition element cation -relationship: has_primary_input CHEBI:33515 ! transition element cation - [Term] id: GO:0000045 name: autophagosome assembly @@ -46287,11 +35464,10 @@ synonym: "polysaccharide biosynthesis" EXACT [] synonym: "polysaccharide formation" EXACT [] synonym: "polysaccharide synthesis" EXACT [] is_a: GO:0005976 ! polysaccharide metabolic process -is_a: GO:0009059 ! macromolecule biosynthetic process -is_a: GO:0016051 ! carbohydrate biosynthetic process +is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:18154 ! polysaccharide -relationship: has_primary_output CHEBI:18154 ! polysaccharide +intersection_of: has_primary_output CHEBI:18154 +relationship: has_primary_output CHEBI:18154 [Term] id: GO:0000272 @@ -46304,11 +35480,10 @@ synonym: "polysaccharide breakdown" EXACT [] synonym: "polysaccharide catabolism" EXACT [] synonym: "polysaccharide degradation" EXACT [] is_a: GO:0005976 ! polysaccharide metabolic process -is_a: GO:0009057 ! macromolecule catabolic process -is_a: GO:0016052 ! carbohydrate catabolic process +is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:18154 ! polysaccharide -relationship: has_primary_input CHEBI:18154 ! polysaccharide +intersection_of: has_primary_input CHEBI:18154 +relationship: has_primary_input CHEBI:18154 [Term] id: GO:0000278 @@ -46342,43 +35517,15 @@ intersection_of: GO:0048285 ! organelle fission intersection_of: results_in_fission_of GO:0005634 ! nucleus relationship: results_in_fission_of GO:0005634 ! nucleus -[Term] -id: GO:0000302 -name: response to reactive oxygen species -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." [GOC:krc] -synonym: "response to active oxygen species" EXACT [] -synonym: "response to AOS" EXACT [] -synonym: "response to reactive oxidative species" EXACT [] -synonym: "response to reactive oxygen intermediate" EXACT [] -synonym: "response to ROI" EXACT [] -synonym: "response to ROS" EXACT [] -is_a: GO:0006979 ! response to oxidative stress -is_a: GO:1901700 ! response to oxygen-containing compound -intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:26523 ! reactive oxygen species -relationship: has_input CHEBI:26523 ! reactive oxygen species - [Term] id: GO:0000303 name: response to superoxide namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion." [GOC:krc, ISBN:0198506732] -is_a: GO:0000305 ! response to oxygen radical -intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:18421 ! superoxide -relationship: has_input CHEBI:18421 ! superoxide - -[Term] -id: GO:0000305 -name: response to oxygen radical -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion." [GOC:krc, ISBN:0124325653] -is_a: GO:0000302 ! response to reactive oxygen species -is_a: GO:0010035 ! response to inorganic substance +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:61073 ! oxygen radical -relationship: has_input CHEBI:61073 ! oxygen radical +intersection_of: has_input CHEBI:18421 +relationship: has_input CHEBI:18421 [Term] id: GO:0000313 @@ -46810,8 +35957,8 @@ synonym: "endogenous peptide receptor activity" NARROW [] synonym: "exogenous peptide receptor activity" NARROW [] is_a: GO:0038023 ! signaling receptor activity intersection_of: GO:0038023 ! signaling receptor activity -intersection_of: has_input CHEBI:16670 ! peptide -relationship: has_input CHEBI:16670 ! peptide +intersection_of: has_input CHEBI:16670 +relationship: has_input CHEBI:16670 relationship: has_part GO:0042277 ! peptide binding [Term] @@ -46989,10 +36136,10 @@ namespace: biological_process def: "A homeostatic process involved in the maintenance of a steady state level of glucose within a cell." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "cell glucose homeostasis" EXACT [GOC:dph, GOC:tb] synonym: "cellular glucose homeostasis" EXACT [] -is_a: GO:0042593 ! glucose homeostasis -is_a: GO:0055082 ! intracellular chemical homeostasis +is_a: GO:0019725 ! cellular homeostasis intersection_of: GO:0019725 ! cellular homeostasis -intersection_of: regulates_levels_of CHEBI:17234 ! glucose +intersection_of: regulates_levels_of CHEBI:17234 +relationship: regulates_levels_of CHEBI:17234 [Term] id: GO:0001692 @@ -47004,8 +36151,8 @@ is_a: GO:0006576 ! biogenic amine metabolic process is_a: GO:0052803 ! imidazole-containing compound metabolic process is_a: GO:0097164 ! ammonium ion metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:58432 ! histaminium -relationship: has_primary_input_or_output CHEBI:58432 ! histaminium +intersection_of: has_primary_input_or_output CHEBI:58432 +relationship: has_primary_input_or_output CHEBI:58432 [Term] id: GO:0001694 @@ -47020,8 +36167,8 @@ synonym: "histamine synthesis" EXACT [] is_a: GO:0001692 ! histamine metabolic process is_a: GO:0042401 ! biogenic amine biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:58432 ! histaminium -relationship: has_primary_output CHEBI:58432 ! histaminium +intersection_of: has_primary_output CHEBI:58432 +relationship: has_primary_output CHEBI:58432 [Term] id: GO:0001695 @@ -47035,8 +36182,8 @@ is_a: GO:0001692 ! histamine metabolic process is_a: GO:0042135 ! neurotransmitter catabolic process is_a: GO:0042402 ! cellular biogenic amine catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:58432 ! histaminium -relationship: has_primary_input CHEBI:58432 ! histaminium +intersection_of: has_primary_input CHEBI:58432 +relationship: has_primary_input CHEBI:58432 [Term] id: GO:0001696 @@ -47570,7 +36717,7 @@ synonym: "serotonin release" RELATED [GOC:tb] is_a: GO:0006837 ! serotonin transport is_a: GO:0023061 ! signal release intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:350546 ! serotonin(1+) +intersection_of: has_primary_input CHEBI:350546 [Term] id: GO:0001821 @@ -47580,7 +36727,7 @@ def: "The regulated release of histamine by a cell or tissue. It is formed by de is_a: GO:0046903 ! secretion is_a: GO:0051608 ! histamine transport intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:58432 ! histaminium +intersection_of: has_primary_input CHEBI:58432 [Term] id: GO:0001822 @@ -47827,8 +36974,8 @@ def: "Combining with a polysaccharide and transmitting the signal to initiate an synonym: "polysaccharide receptor activity" BROAD [] is_a: GO:0038187 ! pattern recognition receptor activity intersection_of: GO:0038023 ! signaling receptor activity -intersection_of: has_input CHEBI:18154 ! polysaccharide -relationship: has_input CHEBI:18154 ! polysaccharide +intersection_of: has_input CHEBI:18154 +relationship: has_input CHEBI:18154 relationship: has_part GO:0030247 ! polysaccharide binding [Term] @@ -48485,7 +37632,7 @@ namespace: biological_process def: "The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:dos, GOC:dph] synonym: "dopaminergic synaptic transmission" EXACT [] is_a: GO:0007268 ! chemical synaptic transmission -relationship: has_participant CHEBI:59905 ! dopaminium(1+) +relationship: has_participant CHEBI:59905 relationship: has_participant CL:0000700 ! dopaminergic neuron [Term] @@ -48614,18 +37761,6 @@ synonym: "regulation of heart contraction rate" EXACT [] synonym: "regulation of rate of heart contraction" EXACT [] is_a: GO:0008016 ! regulation of heart contraction -[Term] -id: GO:0002028 -name: regulation of sodium ion transport -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph] -synonym: "regulation of Na+ transport" EXACT [] -synonym: "regulation of sodium transport" EXACT [] -is_a: GO:0010959 ! regulation of metal ion transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0006814 ! sodium ion transport -relationship: regulates GO:0006814 ! sodium ion transport - [Term] id: GO:0002052 name: positive regulation of neuroblast proliferation @@ -48659,19 +37794,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010463 ! mesenchymal cell proliferation relationship: positively_regulates GO:0010463 ! mesenchymal cell proliferation -[Term] -id: GO:0002054 -name: nucleobase binding -namespace: molecular_function -def: "Binding to a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases." [GOC:hjd] -subset: goslim_pir -is_a: GO:0036094 ! small molecule binding -is_a: GO:0097159 ! organic cyclic compound binding -is_a: GO:1901363 ! heterocyclic compound binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:18282 ! nucleobase -relationship: has_input CHEBI:18282 ! nucleobase - [Term] id: GO:0002062 name: chondrocyte differentiation @@ -50985,7 +40107,7 @@ synonym: "nitric oxide production involved in acute inflammatory response" BROAD synonym: "production of nitric oxide involved in acute inflammatory response" BROAD [] synonym: "production of nitric oxide involved in inflammatory response" EXACT [] is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response -relationship: has_output CHEBI:16480 ! nitric oxide +relationship: has_output CHEBI:16480 [Term] id: GO:0002538 @@ -53402,7 +42524,7 @@ def: "The controlled release of a peptide from a cell or a tissue." [GOC:add] is_a: GO:0015833 ! peptide transport is_a: GO:0046903 ! secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:16670 ! peptide +intersection_of: has_primary_input CHEBI:16670 [Term] id: GO:0002791 @@ -54339,9 +43461,6 @@ def: "Renal process involved in the maintenance of an internal steady state of w synonym: "water homeostasis by the renal system" EXACT [] is_a: GO:0003014 ! renal system process is_a: GO:0050891 ! multicellular organismal-level water homeostasis -intersection_of: GO:0030104 ! water homeostasis -intersection_of: occurs_in UBERON:0001008 ! renal system -relationship: occurs_in UBERON:0001008 ! renal system [Term] id: GO:0003093 @@ -54364,17 +43483,6 @@ intersection_of: GO:0097205 ! renal filtration intersection_of: occurs_in UBERON:0000074 ! renal glomerulus relationship: occurs_in UBERON:0000074 ! renal glomerulus -[Term] -id: GO:0003096 -name: renal sodium ion transport -namespace: biological_process -def: "The directed movement of sodium ions (Na+) by the renal system." [GOC:mtg_cardio] -is_a: GO:0003014 ! renal system process -is_a: GO:0006814 ! sodium ion transport -intersection_of: GO:0006814 ! sodium ion transport -intersection_of: occurs_in UBERON:0001008 ! renal system -relationship: occurs_in UBERON:0001008 ! renal system - [Term] id: GO:0003097 name: renal water transport @@ -55722,9 +44830,9 @@ def: "The process in which an amino acid is transported across a membrane." [GOC comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "amino acid membrane transport" EXACT [] is_a: GO:0006865 ! amino acid transport -is_a: GO:1903825 ! organic acid transmembrane transport +is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:33709 ! amino acid +intersection_of: has_primary_input CHEBI:33709 intersection_of: results_in_transport_across GO:0016020 ! membrane created_by: dph creation_date: 2009-11-02T02:36:11Z @@ -56313,7 +45421,7 @@ id: GO:0003674 name: molecular_function namespace: molecular_function alt_id: GO:0005554 -def: "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process." [GOC:pdt] +def: "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs." [GOC:pdt] comment: Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex. subset: goslim_candida subset: goslim_chembl @@ -56337,11 +45445,10 @@ subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant synonym: "base pairing" NARROW [] -is_a: GO:0097159 ! organic cyclic compound binding -is_a: GO:1901363 ! heterocyclic compound binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:33696 ! nucleic acid -relationship: has_input CHEBI:33696 ! nucleic acid +intersection_of: has_input CHEBI:33696 +relationship: has_input CHEBI:33696 [Term] id: GO:0003677 @@ -56363,10 +45470,10 @@ synonym: "microtubule/chromatin interaction" RELATED [] synonym: "plasmid binding" NARROW [] synonym: "structure specific DNA binding" RELATED [] synonym: "structure-specific DNA binding" RELATED [] -is_a: GO:0003676 ! nucleic acid binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:16991 ! deoxyribonucleic acid -relationship: has_input CHEBI:16991 ! deoxyribonucleic acid +intersection_of: has_input CHEBI:16991 +relationship: has_input CHEBI:16991 [Term] id: GO:0003682 @@ -56394,8 +45501,8 @@ def: "Combining with a steroid hormone and transmitting the signal within the ce synonym: "steroid hormone receptor activity" BROAD [] is_a: GO:0038023 ! signaling receptor activity intersection_of: GO:0038023 ! signaling receptor activity -intersection_of: has_input CHEBI:26764 ! steroid hormone -relationship: has_input CHEBI:26764 ! steroid hormone +intersection_of: has_input CHEBI:26764 +relationship: has_input CHEBI:26764 relationship: part_of GO:0043401 ! steroid hormone mediated signaling pathway property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16717" xsd:anyURI @@ -56423,8 +45530,8 @@ synonym: "poly-A RNA binding" RELATED [] xref: Reactome:R-HSA-203922 "Exportin-5 recognizes 3' overhang of pre-miRNA" is_a: GO:0003676 ! nucleic acid binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:33697 ! ribonucleic acid -relationship: has_input CHEBI:33697 ! ribonucleic acid +intersection_of: has_input CHEBI:33697 +relationship: has_input CHEBI:33697 [Term] id: GO:0003824 @@ -56470,11 +45577,12 @@ is_a: GO:0016788 ! hydrolase activity, acting on ester bonds [Term] id: GO:0004536 -name: deoxyribonuclease activity +name: DNA nuclease activity namespace: molecular_function alt_id: GO:0004537 def: "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah, ISBN:0198547684] synonym: "caspase-activated deoxyribonuclease activity" NARROW [] +synonym: "deoxyribonuclease activity" EXACT [] xref: Reactome:R-HSA-211247 "Cleavage of DNA by DFF40" xref: Reactome:R-HSA-5685994 "Long-range resection of DNA DSBs by EXO1 or DNA2" xref: Reactome:R-HSA-6785986 "DNA nucleases unhook the interstrand crosslink (ICL)" @@ -57354,7 +46462,6 @@ xref: Reactome:R-HSA-983707 "SYK autophosphorylates at the activated BCR" xref: Reactome:R-HSA-983709 "LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B)" xref: RHEA:10596 {source="skos:exactMatch"} is_a: GO:0004672 ! protein kinase activity -relationship: part_of GO:0018108 ! peptidyl-tyrosine phosphorylation [Term] id: GO:0004714 @@ -57444,8 +46551,8 @@ def: "Combining with a glucocorticoid and transmitting the signal within the cel synonym: "glucocorticoid receptor activity" BROAD [] is_a: GO:0003707 ! nuclear steroid receptor activity intersection_of: GO:0038023 ! signaling receptor activity -intersection_of: has_input CHEBI:24261 ! glucocorticoid -relationship: has_input CHEBI:24261 ! glucocorticoid +intersection_of: has_input CHEBI:24261 +relationship: has_input CHEBI:24261 relationship: part_of GO:0042921 ! glucocorticoid receptor signaling pathway relationship: part_of GO:0043402 ! glucocorticoid mediated signaling pathway property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16717" xsd:anyURI @@ -57531,8 +46638,8 @@ namespace: molecular_function def: "Combining with calcitonin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:mah, GOC:signaling, PMID:21649645] is_a: GO:0097642 ! calcitonin family receptor activity intersection_of: GO:0038023 ! signaling receptor activity -intersection_of: has_input CHEBI:3306 ! calcitonin -relationship: has_input CHEBI:3306 ! calcitonin +intersection_of: has_input CHEBI:3306 +relationship: has_input CHEBI:3306 relationship: has_part GO:0032841 ! calcitonin binding [Term] @@ -57554,8 +46661,8 @@ namespace: molecular_function def: "Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:mah, GOC:signaling, PMID:22438981] is_a: GO:0008528 ! G protein-coupled peptide receptor activity intersection_of: GO:0038023 ! signaling receptor activity -intersection_of: has_input CHEBI:5391 ! glucagon -relationship: has_input CHEBI:5391 ! glucagon +intersection_of: has_input CHEBI:5391 +relationship: has_input CHEBI:5391 relationship: part_of GO:0071377 ! cellular response to glucagon stimulus [Term] @@ -57565,8 +46672,8 @@ namespace: molecular_function def: "Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans." [GOC:ai] is_a: GO:0008227 ! G protein-coupled amine receptor activity intersection_of: GO:0038023 ! signaling receptor activity -intersection_of: has_input CHEBI:58432 ! histaminium -relationship: has_input CHEBI:58432 ! histaminium +intersection_of: has_input CHEBI:58432 +relationship: has_input CHEBI:58432 relationship: has_part GO:0051381 ! histamine binding [Term] @@ -57587,8 +46694,8 @@ synonym: "adrenocorticotropin receptor activity" EXACT [] is_a: GO:0004977 ! melanocortin receptor activity is_a: GO:0008188 ! neuropeptide receptor activity intersection_of: GO:0038023 ! signaling receptor activity -intersection_of: has_input CHEBI:3892 ! corticotropin -relationship: has_input CHEBI:3892 ! corticotropin +intersection_of: has_input CHEBI:3892 +relationship: has_input CHEBI:3892 relationship: has_part GO:0042562 ! hormone binding [Term] @@ -57598,8 +46705,8 @@ namespace: molecular_function def: "Combining with oxytocin to initiate a change in cell activity." [GOC:ai] is_a: GO:0008528 ! G protein-coupled peptide receptor activity intersection_of: GO:0038023 ! signaling receptor activity -intersection_of: has_input CHEBI:7872 ! oxytocin -relationship: has_input CHEBI:7872 ! oxytocin +intersection_of: has_input CHEBI:7872 +relationship: has_input CHEBI:7872 [Term] id: GO:0004993 @@ -57616,7 +46723,7 @@ xref: Wikipedia:5-HT_receptor is_a: GO:0008227 ! G protein-coupled amine receptor activity is_a: GO:0099589 ! serotonin receptor activity intersection_of: GO:0008227 ! G protein-coupled amine receptor activity -intersection_of: has_input CHEBI:350546 ! serotonin(1+) +intersection_of: has_input CHEBI:350546 relationship: has_part GO:0051378 ! serotonin binding relationship: part_of GO:0098664 ! G protein-coupled serotonin receptor signaling pathway property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/12942" xsd:anyURI @@ -57633,8 +46740,8 @@ synonym: "SRIF receptor activity" EXACT [Wikipedia:Somatostatin] synonym: "SST receptor activity" EXACT [Wikipedia:Somatostatin] is_a: GO:0008188 ! neuropeptide receptor activity intersection_of: GO:0038023 ! signaling receptor activity -intersection_of: has_input CHEBI:64628 ! somatostatin -relationship: has_input CHEBI:64628 ! somatostatin +intersection_of: has_input CHEBI:64628 +relationship: has_input CHEBI:64628 relationship: part_of GO:0038170 ! somatostatin signaling pathway [Term] @@ -57646,8 +46753,8 @@ def: "Combining with vasopressin to initiate a change in cell activity." [GOC:ai synonym: "vasopressin activated calcium mobilizing receptor activity" NARROW [] is_a: GO:0008528 ! G protein-coupled peptide receptor activity intersection_of: GO:0038023 ! signaling receptor activity -intersection_of: has_input CHEBI:9937 ! vasopressin -relationship: has_input CHEBI:9937 ! vasopressin +intersection_of: has_input CHEBI:9937 +relationship: has_input CHEBI:9937 [Term] id: GO:0005009 @@ -57777,7 +46884,7 @@ synonym: "ion channel activity" BROAD [] is_a: GO:0015075 ! monoatomic ion transmembrane transporter activity is_a: GO:0015267 ! channel activity intersection_of: GO:0015267 ! channel activity -intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion +intersection_of: has_primary_input CHEBI:24867 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI [Term] @@ -57787,7 +46894,13 @@ namespace: molecular_function def: "Enables the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient." [GOC:dph, GOC:mtg_transport] synonym: "intracellular calcium-activated potassium channel" NARROW [] synonym: "polycystin" NARROW [] +is_a: GO:0005261 ! monoatomic cation channel activity is_a: GO:0022836 ! gated channel activity +intersection_of: GO:0022836 ! gated channel activity +intersection_of: has_primary_input CHEBI:23906 +intersection_of: positively_regulated_by GO:0005509 ! calcium ion binding +relationship: positively_regulated_by GO:0005509 ! calcium ion binding +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24605" xsd:anyURI [Term] id: GO:0005230 @@ -57823,7 +46936,7 @@ synonym: "voltage-gated ion channel activity" BROAD [] is_a: GO:0022832 ! voltage-gated channel activity is_a: GO:0022839 ! monoatomic ion gated channel activity intersection_of: GO:0022832 ! voltage-gated channel activity -intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion +intersection_of: has_primary_input CHEBI:24867 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI [Term] @@ -57847,16 +46960,16 @@ xref: Reactome:R-HSA-5577213 "LTCC multimer transports Ca2+ from extracellular r xref: Reactome:R-HSA-9701055 "TRPA1 tetramer transports Ca2+ from extracellular region to cytosol" xref: Reactome:R-HSA-9701141 "TRPV1 transports Ca2+ from extracellular region to cytosol" is_a: GO:0005262 ! calcium channel activity -is_a: GO:0022843 ! voltage-gated monoatomic cation channel activity +is_a: GO:0022832 ! voltage-gated channel activity intersection_of: GO:0022832 ! voltage-gated channel activity -intersection_of: has_primary_input CHEBI:29108 ! calcium(2+) +intersection_of: has_primary_input CHEBI:29108 [Term] id: GO:0005246 name: calcium channel regulator activity namespace: molecular_function def: "Modulates the activity of a calcium channel." [GOC:mah] -is_a: GO:0099106 ! ion channel regulator activity +is_a: GO:0016247 ! channel regulator activity intersection_of: GO:0098772 ! molecular function regulator activity intersection_of: directly_regulates GO:0005262 ! calcium channel activity relationship: directly_regulates GO:0005262 ! calcium channel activity @@ -57877,10 +46990,10 @@ xref: Reactome:R-HSA-169683 "IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lu xref: Reactome:R-HSA-2089943 "TRPC1 translocates calcium from the extracellular region to the cytosol" xref: Reactome:R-HSA-426223 "Cation influx mediated by TRPC3/6/7" xref: Reactome:R-HSA-4420052 "Decreasing cGMP concentration promotes intracellular Ca2+ release in response to WNT" -is_a: GO:0005216 ! monoatomic ion channel activity is_a: GO:0008324 ! monoatomic cation transmembrane transporter activity +is_a: GO:0015267 ! channel activity intersection_of: GO:0015267 ! channel activity -intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation +intersection_of: has_primary_input CHEBI:23906 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI [Term] @@ -57894,22 +47007,10 @@ xref: Reactome:R-HSA-210420 "Ca2+ influx through voltage gated Ca2+ channels" xref: Reactome:R-HSA-3295579 "TRPs transport extracellular Ca2+ to cytosol" xref: Reactome:R-HSA-8949145 "VDAC1,2,3 translocate calcium from the cytosol to the mitochondrial intermembrane space" xref: Reactome:R-HSA-8949178 "MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix" -is_a: GO:0005261 ! monoatomic cation channel activity is_a: GO:0015085 ! calcium ion transmembrane transporter activity +is_a: GO:0015267 ! channel activity intersection_of: GO:0015267 ! channel activity -intersection_of: has_primary_input CHEBI:29108 ! calcium(2+) - -[Term] -id: GO:0005272 -name: sodium channel activity -namespace: molecular_function -def: "Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:BHF, GOC:mtg_transport, GOC:pr, ISBN:0815340729] -xref: Reactome:R-HSA-2730664 "UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol" -xref: Reactome:R-HSA-3295580 "TRPM4,5 transport extracellular Na+ to cytosol" -is_a: GO:0005261 ! monoatomic cation channel activity -is_a: GO:0015081 ! sodium ion transmembrane transporter activity -intersection_of: GO:0015267 ! channel activity -intersection_of: has_primary_input CHEBI:29101 ! sodium(1+) +intersection_of: has_primary_input CHEBI:29108 [Term] id: GO:0005275 @@ -57922,8 +47023,8 @@ synonym: "amine/polyamine transmembrane transporter activity" EXACT [] synonym: "amino acid-polyamine transmembrane transporter activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:32952 ! amine -relationship: has_primary_input CHEBI:32952 ! amine +intersection_of: has_primary_input CHEBI:32952 +relationship: has_primary_input CHEBI:32952 relationship: part_of GO:0015837 ! amine transport [Term] @@ -57933,30 +47034,42 @@ namespace: molecular_function def: "Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai] xref: Reactome:R-HSA-264615 "Loading of acetylcholine in synaptic vesicles" is_a: GO:0005326 ! neurotransmitter transmembrane transporter activity -is_a: GO:0015101 ! organic cation transmembrane transporter activity -is_a: GO:1901375 ! acetate ester transmembrane transporter activity +is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:15355 ! acetylcholine -relationship: has_primary_input CHEBI:15355 ! acetylcholine +intersection_of: has_primary_input CHEBI:15355 +relationship: has_primary_input CHEBI:15355 [Term] -id: GO:0005310 -name: dicarboxylic acid transmembrane transporter activity +id: GO:0005290 +name: L-histidine transmembrane transporter activity namespace: molecular_function -alt_id: GO:0005312 -alt_id: GO:0015365 -def: "Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups." [GOC:ai] -synonym: "dicarboxylate (succinate/fumarate/malate) antiporter activity" RELATED [] -synonym: "dicarboxylate carrier" NARROW [] -synonym: "dicarboxylic acid permease activity" RELATED [] -synonym: "sodium:dicarboxylate/tricarboxylate symporter activity" NARROW [] -xref: Reactome:R-HSA-1614546 "Sulfate is exported to the cytosol in exchange for dicarboxylate" -xref: Reactome:R-HSA-372843 "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]" -is_a: GO:0005342 ! organic acid transmembrane transporter activity +def: "Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "histidine/arginine/lysine/ornithine porter activity" NARROW [] +synonym: "L-histidine transporter activity" BROAD [] +is_a: GO:0015174 ! basic amino acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:35692 ! dicarboxylic acid -relationship: has_primary_input CHEBI:35692 ! dicarboxylic acid -relationship: part_of GO:0006835 ! dicarboxylic acid transport +intersection_of: has_primary_input CHEBI:57595 +relationship: has_primary_input CHEBI:57595 +relationship: part_of GO:0089709 ! L-histidine transmembrane transport + +[Term] +id: GO:0005313 +name: L-glutamate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "glutamate transmembrane transporter activity" BROAD [] +synonym: "glutamate/aspartate porter activity" NARROW [] +synonym: "glutamate/aspartate:sodium symporter activity" NARROW [] +synonym: "L-glutamate transporter activity" BROAD [] +xref: Reactome:R-HSA-210444 "L-Glutamate loading of synaptic vesicle" +xref: Reactome:R-HSA-428052 "SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+" +xref: Reactome:R-HSA-5624256 "Defective SLC17A8 does not exchange cytosolic L-Glu for synaptic vesicle H+" +xref: RHEA:66336 {source="skos:broadMatch"} +is_a: GO:0015172 ! acidic amino acid transmembrane transporter activity +intersection_of: GO:0022857 ! transmembrane transporter activity +intersection_of: has_primary_input CHEBI:29985 +relationship: has_primary_input CHEBI:29985 +relationship: part_of GO:0015813 ! L-glutamate transmembrane transport [Term] id: GO:0005319 @@ -57978,8 +47091,8 @@ xref: Reactome:R-HSA-8848053 "ABCA5 transports CHOL from lysosomal lumen to cyto xref: Reactome:R-HSA-8866329 "MTTP lipidates APOB-100, forming a pre-VLDL" is_a: GO:0005215 ! transporter activity intersection_of: GO:0005215 ! transporter activity -intersection_of: has_primary_input CHEBI:18059 ! lipid -relationship: has_primary_input CHEBI:18059 ! lipid +intersection_of: has_primary_input CHEBI:18059 +relationship: has_primary_input CHEBI:18059 relationship: part_of GO:0006869 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! lipid transport [Term] @@ -57999,8 +47112,8 @@ namespace: molecular_function def: "Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage." [ISBN:0198506732] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:64709 ! organic acid -relationship: has_primary_input CHEBI:64709 ! organic acid +intersection_of: has_primary_input CHEBI:64709 +relationship: has_primary_input CHEBI:64709 relationship: part_of GO:1903825 ! organic acid transmembrane transport [Term] @@ -58014,10 +47127,10 @@ synonym: "glucose permease activity" EXACT [] synonym: "lactose/glucose efflux transporter activity" NARROW [] xref: Reactome:R-HSA-499981 "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2" xref: Reactome:R-HSA-5653873 "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen" -is_a: GO:0015149 ! hexose transmembrane transporter activity +is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:17234 ! glucose -relationship: has_primary_input CHEBI:17234 ! glucose +intersection_of: has_primary_input CHEBI:17234 +relationship: has_primary_input CHEBI:17234 relationship: part_of GO:1904659 ! glucose transmembrane transport [Term] @@ -58025,10 +47138,10 @@ id: GO:0005372 name: water transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of water (H2O) from one side of a membrane to the other." [GOC:ai] -is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity +is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:15377 ! water -relationship: has_primary_input CHEBI:15377 ! water +intersection_of: has_primary_input CHEBI:15377 +relationship: has_primary_input CHEBI:15377 relationship: part_of GO:0006833 ! water transport [Term] @@ -58052,10 +47165,10 @@ xref: Reactome:R-HSA-5623558 "Defective SLC11A2 does not cotransport Fe2+, H+ fr xref: Reactome:R-HSA-5655733 "Defective SLC40A1 does not transport Fe2+ from cytosol to extracellular region" xref: Reactome:R-HSA-904830 "SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region" xref: Reactome:R-HSA-917936 "MCOLN1 transports Fe2+ from endosome lumen to cytosol" -is_a: GO:0046915 ! transition metal ion transmembrane transporter activity +is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:24875 ! iron cation -relationship: has_primary_input CHEBI:24875 ! iron cation +intersection_of: has_primary_input CHEBI:24875 +relationship: has_primary_input CHEBI:24875 relationship: part_of GO:0034755 ! iron ion transmembrane transport property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17162" xsd:anyURI @@ -58078,33 +47191,20 @@ name: steroid binding namespace: molecular_function def: "Binding to a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene." [GOC:jl, ISBN:0198506732] subset: goslim_pir -is_a: GO:0008289 ! lipid binding -is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:35341 ! steroid -relationship: has_input CHEBI:35341 ! steroid +intersection_of: has_input CHEBI:35341 +relationship: has_input CHEBI:35341 [Term] id: GO:0005500 name: juvenile hormone binding namespace: molecular_function def: "Binding to a juvenile hormone, a sesquiterpenoid derivative that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis." [GOC:jl, ISBN:0198506732] -is_a: GO:0019840 ! isoprenoid binding is_a: GO:0042562 ! hormone binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:24943 ! juvenile hormone -relationship: has_input CHEBI:24943 ! juvenile hormone - -[Term] -id: GO:0005504 -name: fatty acid binding -namespace: molecular_function -def: "Binding to a fatty acid, an aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis." [ISBN:0198506732] -is_a: GO:0008289 ! lipid binding -is_a: GO:0033293 ! monocarboxylic acid binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:28868 ! fatty acid anion -relationship: has_input CHEBI:28868 ! fatty acid anion +intersection_of: has_input CHEBI:24943 +relationship: has_input CHEBI:24943 [Term] id: GO:0005506 @@ -58112,10 +47212,10 @@ name: iron ion binding namespace: molecular_function def: "Binding to an iron (Fe) ion." [GOC:ai] synonym: "iron binding" EXACT [] -is_a: GO:0046914 ! transition metal ion binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:24875 ! iron cation -relationship: has_input CHEBI:24875 ! iron cation +intersection_of: has_input CHEBI:24875 +relationship: has_input CHEBI:24875 [Term] id: GO:0005509 @@ -58123,10 +47223,10 @@ name: calcium ion binding namespace: molecular_function def: "Binding to a calcium ion (Ca2+)." [GOC:ai] synonym: "calcium ion storage activity" RELATED [] -is_a: GO:0046872 ! metal ion binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:29108 ! calcium(2+) -relationship: has_input CHEBI:29108 ! calcium(2+) +intersection_of: has_input CHEBI:29108 +relationship: has_input CHEBI:29108 [Term] id: GO:0005515 @@ -58162,10 +47262,10 @@ id: GO:0005536 name: glucose binding namespace: molecular_function def: "Binding to D- or L-enantiomers of glucose." [GOC:jl] -is_a: GO:0048029 ! monosaccharide binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:17234 ! glucose -relationship: has_input CHEBI:17234 ! glucose +intersection_of: has_input CHEBI:17234 +relationship: has_input CHEBI:17234 [Term] id: GO:0005539 @@ -58175,8 +47275,8 @@ def: "Binding to a glycan (polysaccharide) containing a substantial proportion o subset: goslim_chembl is_a: GO:0097367 ! carbohydrate derivative binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:18085 ! glycosaminoglycan -relationship: has_input CHEBI:18085 ! glycosaminoglycan +intersection_of: has_input CHEBI:18085 +relationship: has_input CHEBI:18085 [Term] id: GO:0005540 @@ -58184,10 +47284,10 @@ name: hyaluronic acid binding namespace: molecular_function def: "Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine." [GOC:jl] synonym: "hyaluronan binding" EXACT [] -is_a: GO:0005539 ! glycosaminoglycan binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:16336 ! hyaluronic acid -relationship: has_input CHEBI:16336 ! hyaluronic acid +intersection_of: has_input CHEBI:16336 +relationship: has_input CHEBI:16336 [Term] id: GO:0005575 @@ -58591,7 +47691,7 @@ xref: Wikipedia:Ribosome is_a: GO:0043232 ! intracellular non-membrane-bounded organelle is_a: PR:000050567 ! protein-containing material entity relationship: capable_of_part_of GO:0006412 ! translation -relationship: has_part CHEBI:33697 ! ribonucleic acid +relationship: has_part CHEBI:33697 [Term] id: GO:0005856 @@ -58867,10 +47967,9 @@ subset: prokaryote_subset synonym: "carbohydrate metabolism" EXACT [] xref: Wikipedia:Carbohydrate_metabolism is_a: GO:0044238 ! primary metabolic process -is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:16646 ! carbohydrate -relationship: has_primary_input_or_output CHEBI:16646 ! carbohydrate +intersection_of: has_primary_input_or_output CHEBI:16646 +relationship: has_primary_input_or_output CHEBI:16646 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22880" xsd:anyURI created_by: jl creation_date: 2012-10-23T15:40:34Z @@ -58886,11 +47985,10 @@ synonym: "glycan metabolic process" NARROW [] synonym: "glycan metabolism" NARROW [] synonym: "multicellular organismal polysaccharide metabolic process" NARROW [] synonym: "polysaccharide metabolism" EXACT [] -is_a: GO:0005975 ! carbohydrate metabolic process -is_a: GO:0043170 ! macromolecule metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:18154 ! polysaccharide -relationship: has_primary_input_or_output CHEBI:18154 ! polysaccharide +intersection_of: has_primary_input_or_output CHEBI:18154 +relationship: has_primary_input_or_output CHEBI:18154 [Term] id: GO:0005977 @@ -58898,11 +47996,12 @@ name: glycogen metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages." [ISBN:0198506732] synonym: "glycogen metabolism" EXACT [] -is_a: GO:0006073 ! cellular glucan metabolic process +is_a: GO:0005975 ! carbohydrate metabolic process is_a: GO:0006112 ! energy reserve metabolic process +is_a: GO:0044042 ! glucan metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:28087 ! glycogen -relationship: has_primary_input_or_output CHEBI:28087 ! glycogen +intersection_of: has_primary_input_or_output CHEBI:28087 +relationship: has_primary_input_or_output CHEBI:28087 [Term] id: GO:0005978 @@ -58917,8 +48016,8 @@ xref: MetaCyc:GLYCOGENSYNTH-PWY is_a: GO:0005977 ! glycogen metabolic process is_a: GO:0009250 ! glucan biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:28087 ! glycogen -relationship: has_primary_output CHEBI:28087 ! glycogen +intersection_of: has_primary_output CHEBI:28087 +relationship: has_primary_output CHEBI:28087 [Term] id: GO:0005979 @@ -58946,11 +48045,10 @@ synonym: "glycogen degradation" EXACT [] synonym: "glycogenolysis" EXACT [GOC:sl] xref: MetaCyc:GLYCOCAT-PWY is_a: GO:0005977 ! glycogen metabolic process -is_a: GO:0009251 ! glucan catabolic process -is_a: GO:0044247 ! cellular polysaccharide catabolic process +is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:28087 ! glycogen -relationship: has_primary_input CHEBI:28087 ! glycogen +intersection_of: has_primary_input CHEBI:28087 +relationship: has_primary_input CHEBI:28087 [Term] id: GO:0005981 @@ -58961,24 +48059,12 @@ synonym: "regulation of glycogen breakdown" EXACT [] synonym: "regulation of glycogen catabolism" EXACT [] synonym: "regulation of glycogen degradation" EXACT [] synonym: "regulation of glycogenolysis" EXACT [GOC:sl] -is_a: GO:0043471 ! regulation of cellular carbohydrate catabolic process +is_a: GO:0043470 ! regulation of carbohydrate catabolic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005980 ! glycogen catabolic process relationship: regulates GO:0005980 ! glycogen catabolic process -[Term] -id: GO:0005996 -name: monosaccharide metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." [ISBN:0198506732] -synonym: "monosaccharide metabolism" EXACT [] -is_a: GO:0005975 ! carbohydrate metabolic process -is_a: GO:0044281 ! small molecule metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:35381 ! monosaccharide -relationship: has_primary_input_or_output CHEBI:35381 ! monosaccharide - [Term] id: GO:0006006 name: glucose metabolic process @@ -58988,8 +48074,8 @@ synonym: "cellular glucose metabolic process" EXACT [GOC:vw] synonym: "glucose metabolism" EXACT [] is_a: GO:0019318 ! hexose metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:17234 ! glucose -relationship: has_primary_input_or_output CHEBI:17234 ! glucose +intersection_of: has_primary_input_or_output CHEBI:17234 +relationship: has_primary_input_or_output CHEBI:17234 [Term] id: GO:0006007 @@ -59000,40 +48086,10 @@ synonym: "glucose breakdown" EXACT [] synonym: "glucose catabolism" EXACT [] synonym: "glucose degradation" EXACT [] is_a: GO:0006006 ! glucose metabolic process -is_a: GO:0019320 ! hexose catabolic process +is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:17234 ! glucose -relationship: has_primary_input CHEBI:17234 ! glucose - -[Term] -id: GO:0006022 -name: aminoglycan metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] -synonym: "aminoglycan metabolism" EXACT [] -is_a: GO:0043170 ! macromolecule metabolic process -is_a: GO:1901135 ! carbohydrate derivative metabolic process -is_a: GO:1901564 ! organonitrogen compound metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:22506 ! aminoglycan -relationship: has_primary_input_or_output CHEBI:22506 ! aminoglycan - -[Term] -id: GO:0006023 -name: aminoglycan biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] -synonym: "aminoglycan anabolism" EXACT [] -synonym: "aminoglycan biosynthesis" EXACT [] -synonym: "aminoglycan formation" EXACT [] -synonym: "aminoglycan synthesis" EXACT [] -is_a: GO:0006022 ! aminoglycan metabolic process -is_a: GO:0009059 ! macromolecule biosynthetic process -is_a: GO:1901137 ! carbohydrate derivative biosynthetic process -is_a: GO:1901566 ! organonitrogen compound biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:22506 ! aminoglycan -relationship: has_primary_output CHEBI:22506 ! aminoglycan +intersection_of: has_primary_input CHEBI:17234 +relationship: has_primary_input CHEBI:17234 [Term] id: GO:0006024 @@ -59044,27 +48100,11 @@ synonym: "glycosaminoglycan anabolism" EXACT [] synonym: "glycosaminoglycan biosynthesis" EXACT [] synonym: "glycosaminoglycan formation" EXACT [] synonym: "glycosaminoglycan synthesis" EXACT [] -is_a: GO:0006023 ! aminoglycan biosynthetic process +is_a: GO:0009058 ! biosynthetic process is_a: GO:0030203 ! glycosaminoglycan metabolic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:18085 ! glycosaminoglycan -relationship: has_primary_output CHEBI:18085 ! glycosaminoglycan - -[Term] -id: GO:0006026 -name: aminoglycan catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] -synonym: "aminoglycan breakdown" EXACT [] -synonym: "aminoglycan catabolism" EXACT [] -synonym: "aminoglycan degradation" EXACT [] -is_a: GO:0006022 ! aminoglycan metabolic process -is_a: GO:0009057 ! macromolecule catabolic process -is_a: GO:1901136 ! carbohydrate derivative catabolic process -is_a: GO:1901565 ! organonitrogen compound catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:22506 ! aminoglycan -relationship: has_primary_input CHEBI:22506 ! aminoglycan +intersection_of: has_primary_output CHEBI:18085 +relationship: has_primary_output CHEBI:18085 [Term] id: GO:0006027 @@ -59074,11 +48114,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of glycosam synonym: "glycosaminoglycan breakdown" EXACT [] synonym: "glycosaminoglycan catabolism" EXACT [] synonym: "glycosaminoglycan degradation" EXACT [] -is_a: GO:0006026 ! aminoglycan catabolic process +is_a: GO:0009056 ! catabolic process is_a: GO:0030203 ! glycosaminoglycan metabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:18085 ! glycosaminoglycan -relationship: has_primary_input CHEBI:18085 ! glycosaminoglycan +intersection_of: has_primary_input CHEBI:18085 +relationship: has_primary_input CHEBI:18085 [Term] id: GO:0006029 @@ -59087,33 +48127,10 @@ namespace: biological_process def: "The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans." [GOC:mah, ISBN:0198506732] synonym: "proteoglycan metabolism" EXACT [] synonym: "proteoglycan sulfate transfer" NARROW [] -is_a: GO:0009100 ! glycoprotein metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:37396 ! proteoglycan -relationship: has_primary_input_or_output CHEBI:37396 ! proteoglycan - -[Term] -id: GO:0006066 -name: alcohol metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom." [ISBN:0198506732] -subset: goslim_drosophila -subset: goslim_pir -synonym: "alcohol metabolism" EXACT [] -is_a: GO:0044281 ! small molecule metabolic process -is_a: GO:1901615 ! organic hydroxy compound metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:30879 ! alcohol -relationship: has_primary_input_or_output CHEBI:30879 ! alcohol - -[Term] -id: GO:0006073 -name: cellular glucan metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues, occurring at the level of an individual cell." [ISBN:0198547684] -synonym: "cellular glucan metabolism" EXACT [] -is_a: GO:0044042 ! glucan metabolic process -is_a: GO:0044264 ! cellular polysaccharide metabolic process +intersection_of: has_primary_input_or_output CHEBI:37396 +relationship: has_primary_input_or_output CHEBI:37396 [Term] id: GO:0006081 @@ -59127,8 +48144,8 @@ synonym: "alkanal metabolism" EXACT [] is_a: GO:0044237 ! cellular metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:17478 ! aldehyde -relationship: has_primary_input_or_output CHEBI:17478 ! aldehyde +intersection_of: has_primary_input_or_output CHEBI:17478 +relationship: has_primary_input_or_output CHEBI:17478 [Term] id: GO:0006082 @@ -59141,19 +48158,8 @@ is_a: GO:0044237 ! cellular metabolic process is_a: GO:0044281 ! small molecule metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:64709 ! organic acid -relationship: has_primary_input_or_output CHEBI:64709 ! organic acid - -[Term] -id: GO:0006083 -name: acetate metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving acetate, the anion of acetic acid." [GOC:go_curators] -synonym: "acetate metabolism" EXACT [] -is_a: GO:0032787 ! monocarboxylic acid metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:30089 ! acetate -relationship: has_primary_input_or_output CHEBI:30089 ! acetate +intersection_of: has_primary_input_or_output CHEBI:64709 +relationship: has_primary_input_or_output CHEBI:64709 [Term] id: GO:0006091 @@ -59185,10 +48191,10 @@ synonym: "glucose biosynthetic process" EXACT [] xref: MetaCyc:GLUCONEO-PWY xref: Wikipedia:Gluconeogenesis is_a: GO:0006006 ! glucose metabolic process -is_a: GO:0019319 ! hexose biosynthetic process +is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:17234 ! glucose -relationship: has_primary_output CHEBI:17234 ! glucose +intersection_of: has_primary_output CHEBI:17234 +relationship: has_primary_output CHEBI:17234 [Term] id: GO:0006109 @@ -59210,8 +48216,8 @@ def: "Any process that modulates the frequency, rate or extent of gluconeogenesi synonym: "regulation of gluconeogenesis involved in cellular glucose homeostasis" RELATED [] synonym: "regulation of glucose biosynthesis" BROAD [] synonym: "regulation of glucose biosynthetic process" BROAD [] +is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0010906 ! regulation of glucose metabolic process -is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006094 ! gluconeogenesis relationship: regulates GO:0006094 ! gluconeogenesis @@ -59227,16 +48233,6 @@ subset: goslim_pir synonym: "energy reserve metabolism" EXACT [] is_a: GO:0015980 ! energy derivation by oxidation of organic compounds -[Term] -id: GO:0006113 -name: fermentation -namespace: biological_process -def: "The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP)." [GOC:curators, ISBN:0201090910, MetaCyc:Fermentation] -subset: goslim_pir -xref: MetaCyc:FERMENTATION-PWY -xref: Wikipedia:Fermentation_(biochemistry) -is_a: GO:0015980 ! energy derivation by oxidation of organic compounds - [Term] id: GO:0006139 name: nucleobase-containing compound metabolic process @@ -59250,14 +48246,11 @@ synonym: "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolis synonym: "nucleobase, nucleoside and nucleotide metabolic process" RELATED [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] -is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0034641 ! cellular nitrogen compound metabolic process is_a: GO:0044238 ! primary metabolic process -is_a: GO:0046483 ! heterocycle metabolic process -is_a: GO:1901360 ! organic cyclic compound metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:61120 ! nucleobase-containing molecular entity -relationship: has_primary_input_or_output CHEBI:61120 ! nucleobase-containing molecular entity +intersection_of: has_primary_input_or_output CHEBI:61120 +relationship: has_primary_input_or_output CHEBI:61120 [Term] id: GO:0006259 @@ -59274,11 +48267,10 @@ subset: goslim_pir subset: goslim_plant synonym: "cellular DNA metabolism" EXACT [] synonym: "DNA metabolism" EXACT [] -is_a: GO:0044260 ! cellular macromolecule metabolic process -is_a: GO:0090304 ! nucleic acid metabolic process +is_a: GO:0043170 ! macromolecule metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:16991 ! deoxyribonucleic acid -relationship: has_primary_input_or_output CHEBI:16991 ! deoxyribonucleic acid +intersection_of: has_primary_input_or_output CHEBI:16991 +relationship: has_primary_input_or_output CHEBI:16991 [Term] id: GO:0006308 @@ -59289,12 +48281,11 @@ synonym: "DNA breakdown" EXACT [] synonym: "DNA catabolism" EXACT [] synonym: "DNA degradation" EXACT [] is_a: GO:0006259 ! DNA metabolic process -is_a: GO:0034655 ! nucleobase-containing compound catabolic process -is_a: GO:0044265 ! cellular macromolecule catabolic process +is_a: GO:0009057 ! macromolecule catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:16991 ! deoxyribonucleic acid -relationship: has_part GO:0004536 ! deoxyribonuclease activity -relationship: has_primary_input CHEBI:16991 ! deoxyribonucleic acid +intersection_of: has_primary_input CHEBI:16991 +relationship: has_part GO:0004536 ! DNA nuclease activity +relationship: has_primary_input CHEBI:16991 [Term] id: GO:0006309 @@ -59369,12 +48360,11 @@ subset: goslim_yeast synonym: "RNA breakdown" EXACT [] synonym: "RNA catabolism" EXACT [] synonym: "RNA degradation" EXACT [] +is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:0016070 ! RNA metabolic process -is_a: GO:0034655 ! nucleobase-containing compound catabolic process -is_a: GO:0044265 ! cellular macromolecule catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:33697 ! ribonucleic acid -relationship: has_primary_input CHEBI:33697 ! ribonucleic acid +intersection_of: has_primary_input CHEBI:33697 +relationship: has_primary_input CHEBI:33697 [Term] id: GO:0006403 @@ -59408,15 +48398,14 @@ synonym: "protein formation" EXACT [] synonym: "protein synthesis" EXACT [] synonym: "protein translation" EXACT [] xref: Wikipedia:Translation_(genetics) +is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0019538 ! protein metabolic process -is_a: GO:0034645 ! cellular macromolecule biosynthetic process -is_a: GO:0043043 ! peptide biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:16541 ! protein polypeptide chain +intersection_of: has_primary_output CHEBI:16541 intersection_of: part_of GO:0010467 ! gene expression relationship: ends_with GO:0006415 ! translational termination relationship: has_part GO:0006414 ! translational elongation -relationship: has_primary_output CHEBI:16541 ! protein polypeptide chain +relationship: has_primary_output CHEBI:16541 relationship: part_of GO:0010467 ! gene expression relationship: starts_with GO:0006413 ! translational initiation @@ -59446,7 +48435,7 @@ def: "The successive addition of amino acid residues to a nascent polypeptide ch subset: goslim_yeast synonym: "protein synthesis elongation" BROAD [] synonym: "translation elongation" EXACT [] -is_a: GO:0034645 ! cellular macromolecule biosynthetic process +is_a: GO:0009059 ! macromolecule biosynthetic process relationship: part_of GO:0006412 ! translation [Term] @@ -59473,10 +48462,9 @@ synonym: "regulation of protein anabolism" EXACT [] synonym: "regulation of protein biosynthesis" EXACT [] synonym: "regulation of protein formation" EXACT [] synonym: "regulation of protein synthesis" EXACT [] +is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0010608 ! post-transcriptional regulation of gene expression -is_a: GO:0034248 ! regulation of amide metabolic process is_a: GO:0051246 ! regulation of protein metabolic process -is_a: GO:2000112 ! regulation of cellular macromolecule biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006412 ! translation relationship: regulates GO:0006412 ! translation @@ -59487,6 +48475,7 @@ name: regulation of translational initiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of translational initiation." [GOC:go_curators] is_a: GO:0006417 ! regulation of translation +is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006413 ! translational initiation relationship: regulates GO:0006413 ! translational initiation @@ -59560,13 +48549,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of a glycop synonym: "glycoprotein breakdown" EXACT [] synonym: "glycoprotein catabolism" EXACT [] synonym: "glycoprotein degradation" EXACT [] +is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:0009100 ! glycoprotein metabolic process -is_a: GO:0030163 ! protein catabolic process -is_a: GO:0044265 ! cellular macromolecule catabolic process -is_a: GO:1901136 ! carbohydrate derivative catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:17089 ! glycoprotein -relationship: has_primary_input CHEBI:17089 ! glycoprotein +intersection_of: has_primary_input CHEBI:17089 +relationship: has_primary_input CHEBI:17089 [Term] id: GO:0006518 @@ -59575,11 +48562,10 @@ namespace: biological_process def: "The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." [GOC:go_curators] subset: goslim_pir synonym: "peptide metabolism" EXACT [] -is_a: GO:0043603 ! amide metabolic process -is_a: GO:1901564 ! organonitrogen compound metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:16670 ! peptide -relationship: has_primary_input_or_output CHEBI:16670 ! peptide +intersection_of: has_primary_input_or_output CHEBI:16670 +relationship: has_primary_input_or_output CHEBI:16670 [Term] id: GO:0006520 @@ -59602,8 +48588,8 @@ is_a: GO:0019752 ! carboxylic acid metabolic process is_a: GO:0044238 ! primary metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:37022 ! amino-acid anion -relationship: has_primary_input_or_output CHEBI:37022 ! amino-acid anion +intersection_of: has_primary_input_or_output CHEBI:37022 +relationship: has_primary_input_or_output CHEBI:37022 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI [Term] @@ -59614,6 +48600,7 @@ def: "Any process that modulates the frequency, rate or extent of the chemical r synonym: "regulation of amino acid metabolism" EXACT [] is_a: GO:0010565 ! regulation of cellular ketone metabolic process is_a: GO:0033238 ! regulation of amine metabolic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006520 ! amino acid metabolic process @@ -59631,8 +48618,8 @@ xref: Wikipedia:Glutamic_acid is_a: GO:0009064 ! glutamine family amino acid metabolic process is_a: GO:0043648 ! dicarboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:14321 ! glutamate(1-) -relationship: has_primary_input_or_output CHEBI:14321 ! glutamate(1-) +intersection_of: has_primary_input_or_output CHEBI:14321 +relationship: has_primary_input_or_output CHEBI:14321 [Term] id: GO:0006537 @@ -59650,11 +48637,10 @@ synonym: "glutamate synthesis" EXACT [] synonym: "glutamic acid biosynthesis" EXACT [] synonym: "glutamic acid biosynthetic process" EXACT [] is_a: GO:0006536 ! glutamate metabolic process -is_a: GO:0008652 ! amino acid biosynthetic process is_a: GO:0009084 ! glutamine family amino acid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:14321 ! glutamate(1-) -relationship: has_primary_output CHEBI:14321 ! glutamate(1-) +intersection_of: has_primary_output CHEBI:14321 +relationship: has_primary_output CHEBI:14321 [Term] id: GO:0006538 @@ -59669,11 +48655,10 @@ synonym: "glutamate degradation" EXACT [] synonym: "glutamic acid catabolic process" EXACT [] synonym: "glutamic acid catabolism" EXACT [] is_a: GO:0006536 ! glutamate metabolic process -is_a: GO:0009063 ! amino acid catabolic process is_a: GO:0009065 ! glutamine family amino acid catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:14321 ! glutamate(1-) -relationship: has_primary_input CHEBI:14321 ! glutamate(1-) +intersection_of: has_primary_input CHEBI:14321 +relationship: has_primary_input CHEBI:14321 [Term] id: GO:0006544 @@ -59683,8 +48668,8 @@ def: "The chemical reactions and pathways involving glycine, aminoethanoic acid. synonym: "glycine metabolism" EXACT [] is_a: GO:0009069 ! serine family amino acid metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:57305 ! glycine zwitterion -relationship: has_primary_input_or_output CHEBI:57305 ! glycine zwitterion +intersection_of: has_primary_input_or_output CHEBI:57305 +relationship: has_primary_input_or_output CHEBI:57305 [Term] id: GO:0006545 @@ -59699,8 +48684,8 @@ xref: MetaCyc:GLYCINE-SYN2-PWY is_a: GO:0006544 ! glycine metabolic process is_a: GO:0009070 ! serine family amino acid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:57305 ! glycine zwitterion -relationship: has_primary_output CHEBI:57305 ! glycine zwitterion +intersection_of: has_primary_output CHEBI:57305 +relationship: has_primary_output CHEBI:57305 [Term] id: GO:0006546 @@ -59713,8 +48698,8 @@ synonym: "glycine degradation" EXACT [] is_a: GO:0006544 ! glycine metabolic process is_a: GO:0009071 ! serine family amino acid catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:57305 ! glycine zwitterion -relationship: has_primary_input CHEBI:57305 ! glycine zwitterion +intersection_of: has_primary_input CHEBI:57305 +relationship: has_primary_input CHEBI:57305 [Term] id: GO:0006575 @@ -59733,8 +48718,8 @@ synonym: "modified amino acid metabolism" EXACT [GOC:mah] is_a: GO:0044237 ! cellular metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:83821 ! amino acid derivative -relationship: has_primary_input_or_output CHEBI:83821 ! amino acid derivative +intersection_of: has_primary_input_or_output CHEBI:83821 +relationship: has_primary_input_or_output CHEBI:83821 [Term] id: GO:0006576 @@ -59755,10 +48740,9 @@ synonym: "acetylcholine catabolism" EXACT [] synonym: "acetylcholine degradation" EXACT [] is_a: GO:0008291 ! acetylcholine metabolic process is_a: GO:0042135 ! neurotransmitter catabolic process -is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:15355 ! acetylcholine -relationship: has_primary_input CHEBI:15355 ! acetylcholine +intersection_of: has_primary_input CHEBI:15355 +relationship: has_primary_input CHEBI:15355 [Term] id: GO:0006584 @@ -59769,22 +48753,8 @@ synonym: "catecholamine metabolism" EXACT [] is_a: GO:0006576 ! biogenic amine metabolic process is_a: GO:0009712 ! catechol-containing compound metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:33567 ! catecholamine -relationship: has_primary_input_or_output CHEBI:33567 ! catecholamine - -[Term] -id: GO:0006586 -name: indolalkylamine metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." [GOC:curators] -synonym: "indolalkylamine metabolism" EXACT [] -synonym: "indolamine metabolic process" BROAD [] -synonym: "indolamine metabolism" BROAD [] -is_a: GO:0006576 ! biogenic amine metabolic process -is_a: GO:0042430 ! indole-containing compound metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:38631 ! aminoalkylindole -relationship: has_primary_input_or_output CHEBI:38631 ! aminoalkylindole +intersection_of: has_primary_input_or_output CHEBI:33567 +relationship: has_primary_input_or_output CHEBI:33567 [Term] id: GO:0006590 @@ -59828,74 +48798,8 @@ xref: Wikipedia:Lipid_metabolism is_a: GO:0044238 ! primary metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:18059 ! lipid -relationship: has_primary_input_or_output CHEBI:18059 ! lipid - -[Term] -id: GO:0006631 -name: fatty acid metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis." [ISBN:0198547684] -synonym: "fatty acid metabolism" EXACT [] -xref: Wikipedia:Fatty_acid_metabolism -is_a: GO:0032787 ! monocarboxylic acid metabolic process -is_a: GO:0044255 ! cellular lipid metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:28868 ! fatty acid anion -relationship: has_primary_input_or_output CHEBI:28868 ! fatty acid anion - -[Term] -id: GO:0006633 -name: fatty acid biosynthetic process -namespace: biological_process -alt_id: GO:0000037 -def: "The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes." [GOC:mah, ISBN:0198506732] -synonym: "fatty acid anabolism" EXACT [] -synonym: "fatty acid biosynthesis" EXACT [] -synonym: "fatty acid formation" EXACT [] -synonym: "fatty acid synthesis" EXACT [] -xref: MetaCyc:FASYN-INITIAL-PWY -xref: MetaCyc:PWY-4381 -xref: MetaCyc:PWY-5156 -xref: Wikipedia:Fatty_acid_synthesis -is_a: GO:0006631 ! fatty acid metabolic process -is_a: GO:0008610 ! lipid biosynthetic process -is_a: GO:0072330 ! monocarboxylic acid biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:28868 ! fatty acid anion -relationship: has_primary_output CHEBI:28868 ! fatty acid anion - -[Term] -id: GO:0006643 -name: membrane lipid metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane." [GOC:ai] -synonym: "membrane lipid metabolism" EXACT [] -is_a: GO:0044255 ! cellular lipid metabolic process - -[Term] -id: GO:0006664 -name: glycolipid metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent." [ISBN:0198547684] -synonym: "glycolipid metabolism" EXACT [] -is_a: GO:0006643 ! membrane lipid metabolic process -is_a: GO:1903509 ! liposaccharide metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:33563 ! glycolipid -relationship: has_primary_input_or_output CHEBI:33563 ! glycolipid - -[Term] -id: GO:0006665 -name: sphingolipid metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [GOC:mah, ISBN:0198506732] -synonym: "sphingolipid metabolism" EXACT [] -is_a: GO:0006643 ! membrane lipid metabolic process -is_a: GO:1901564 ! organonitrogen compound metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:26739 ! sphingolipid -relationship: has_primary_input_or_output CHEBI:26739 ! sphingolipid +intersection_of: has_primary_input_or_output CHEBI:18059 +relationship: has_primary_input_or_output CHEBI:18059 [Term] id: GO:0006687 @@ -59903,11 +48807,10 @@ name: glycosphingolipid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide." [ISBN:0198547684] synonym: "glycosphingolipid metabolism" EXACT [] -is_a: GO:0006664 ! glycolipid metabolic process -is_a: GO:0006665 ! sphingolipid metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:24402 ! glycosphingolipid -relationship: has_primary_input_or_output CHEBI:24402 ! glycosphingolipid +intersection_of: has_primary_input_or_output CHEBI:24402 +relationship: has_primary_input_or_output CHEBI:24402 [Term] id: GO:0006688 @@ -59919,11 +48822,10 @@ synonym: "glycosphingolipid biosynthesis" EXACT [] synonym: "glycosphingolipid formation" EXACT [] synonym: "glycosphingolipid synthesis" EXACT [] is_a: GO:0006687 ! glycosphingolipid metabolic process -is_a: GO:0009247 ! glycolipid biosynthetic process -is_a: GO:0030148 ! sphingolipid biosynthetic process +is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:24402 ! glycosphingolipid -relationship: has_primary_output CHEBI:24402 ! glycosphingolipid +intersection_of: has_primary_output CHEBI:24402 +relationship: has_primary_output CHEBI:24402 [Term] id: GO:0006694 @@ -59940,8 +48842,8 @@ is_a: GO:0008202 ! steroid metabolic process is_a: GO:0008610 ! lipid biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:35341 ! steroid -relationship: has_primary_output CHEBI:35341 ! steroid +intersection_of: has_primary_output CHEBI:35341 +relationship: has_primary_output CHEBI:35341 [Term] id: GO:0006699 @@ -59957,8 +48859,8 @@ is_a: GO:0008206 ! bile acid metabolic process is_a: GO:0072330 ! monocarboxylic acid biosynthetic process is_a: GO:1901617 ! organic hydroxy compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:36235 ! bile acid anion -relationship: has_primary_output CHEBI:36235 ! bile acid anion +intersection_of: has_primary_output CHEBI:36235 +relationship: has_primary_output CHEBI:36235 [Term] id: GO:0006700 @@ -59969,13 +48871,13 @@ synonym: "C21-steroid hormone anabolism" EXACT [] synonym: "C21-steroid hormone biosynthesis" EXACT [] synonym: "C21-steroid hormone formation" EXACT [] synonym: "C21-steroid hormone synthesis" EXACT [] +is_a: GO:0006694 ! steroid biosynthetic process is_a: GO:0008207 ! C21-steroid hormone metabolic process is_a: GO:0042446 ! hormone biosynthetic process is_a: GO:0044249 ! cellular biosynthetic process -is_a: GO:0120178 ! steroid hormone biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:64600 ! C21-steroid hormone -relationship: has_primary_output CHEBI:64600 ! C21-steroid hormone +intersection_of: has_primary_output CHEBI:64600 +relationship: has_primary_output CHEBI:64600 [Term] id: GO:0006701 @@ -59986,13 +48888,11 @@ synonym: "progesterone anabolism" EXACT [] synonym: "progesterone biosynthesis" EXACT [] synonym: "progesterone formation" EXACT [] synonym: "progesterone synthesis" EXACT [] -is_a: GO:0006700 ! C21-steroid hormone biosynthetic process -is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0009058 ! biosynthetic process is_a: GO:0042448 ! progesterone metabolic process -is_a: GO:0120255 ! olefinic compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:17026 ! progesterone -relationship: has_primary_output CHEBI:17026 ! progesterone +intersection_of: has_primary_output CHEBI:17026 +relationship: has_primary_output CHEBI:17026 [Term] id: GO:0006704 @@ -60004,10 +48904,10 @@ synonym: "glucocorticoid biosynthesis" EXACT [] synonym: "glucocorticoid formation" EXACT [] synonym: "glucocorticoid synthesis" EXACT [] is_a: GO:0008211 ! glucocorticoid metabolic process -is_a: GO:0120178 ! steroid hormone biosynthetic process +is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:24261 ! glucocorticoid -relationship: has_primary_output CHEBI:24261 ! glucocorticoid +intersection_of: has_primary_output CHEBI:24261 +relationship: has_primary_output CHEBI:24261 [Term] id: GO:0006705 @@ -60019,11 +48919,11 @@ synonym: "mineralocorticoid biosynthesis" EXACT [] synonym: "mineralocorticoid formation" EXACT [] synonym: "mineralocorticoid synthesis" EXACT [] is_a: GO:0008212 ! mineralocorticoid metabolic process +is_a: GO:0009058 ! biosynthetic process is_a: GO:0042446 ! hormone biosynthetic process -is_a: GO:0120178 ! steroid hormone biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:25354 ! mineralocorticoid -relationship: has_primary_output CHEBI:25354 ! mineralocorticoid +intersection_of: has_primary_output CHEBI:25354 +relationship: has_primary_output CHEBI:25354 [Term] id: GO:0006706 @@ -60034,11 +48934,10 @@ synonym: "steroid breakdown" EXACT [] synonym: "steroid catabolism" EXACT [] synonym: "steroid degradation" EXACT [] is_a: GO:0008202 ! steroid metabolic process -is_a: GO:0016042 ! lipid catabolic process -is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:35341 ! steroid -relationship: has_primary_input CHEBI:35341 ! steroid +intersection_of: has_primary_input CHEBI:35341 +relationship: has_primary_input CHEBI:35341 [Term] id: GO:0006709 @@ -60048,13 +48947,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of progeste synonym: "progesterone breakdown" EXACT [] synonym: "progesterone catabolism" EXACT [] synonym: "progesterone degradation" EXACT [] -is_a: GO:0008208 ! C21-steroid hormone catabolic process -is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0009056 ! catabolic process is_a: GO:0042448 ! progesterone metabolic process -is_a: GO:0120256 ! olefinic compound catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:17026 ! progesterone -relationship: has_primary_input CHEBI:17026 ! progesterone +intersection_of: has_primary_input CHEBI:17026 +relationship: has_primary_input CHEBI:17026 [Term] id: GO:0006712 @@ -60064,12 +48961,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of mineralo synonym: "mineralocorticoid breakdown" EXACT [] synonym: "mineralocorticoid catabolism" EXACT [] synonym: "mineralocorticoid degradation" EXACT [] -is_a: GO:0006706 ! steroid catabolic process is_a: GO:0008212 ! mineralocorticoid metabolic process is_a: GO:0042447 ! hormone catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:25354 ! mineralocorticoid -relationship: has_primary_input CHEBI:25354 ! mineralocorticoid +intersection_of: has_primary_input CHEBI:25354 +relationship: has_primary_input CHEBI:25354 [Term] id: GO:0006713 @@ -60079,22 +48975,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of glucocor synonym: "glucocorticoid breakdown" EXACT [] synonym: "glucocorticoid catabolism" EXACT [] synonym: "glucocorticoid degradation" EXACT [] -is_a: GO:0006706 ! steroid catabolic process is_a: GO:0008211 ! glucocorticoid metabolic process +is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:24261 ! glucocorticoid -relationship: has_primary_input CHEBI:24261 ! glucocorticoid - -[Term] -id: GO:0006714 -name: sesquiterpenoid metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units." [ISBN:0198547684] -synonym: "sesquiterpenoid metabolism" EXACT [] -is_a: GO:0006721 ! terpenoid metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:26658 ! sesquiterpenoid -relationship: has_primary_input_or_output CHEBI:26658 ! sesquiterpenoid +intersection_of: has_primary_input CHEBI:24261 +relationship: has_primary_input CHEBI:24261 [Term] id: GO:0006716 @@ -60102,11 +48987,11 @@ name: juvenile hormone metabolic process namespace: biological_process def: "The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis." [GOC:go_curators, ISBN:0198547684] synonym: "juvenile hormone metabolism" EXACT [] -is_a: GO:0006714 ! sesquiterpenoid metabolic process +is_a: GO:0008152 ! metabolic process is_a: GO:0042445 ! hormone metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:24943 ! juvenile hormone -relationship: has_primary_input_or_output CHEBI:24943 ! juvenile hormone +intersection_of: has_primary_input_or_output CHEBI:24943 +relationship: has_primary_input_or_output CHEBI:24943 [Term] id: GO:0006718 @@ -60118,11 +49003,11 @@ synonym: "juvenile hormone biosynthesis" EXACT [] synonym: "juvenile hormone formation" EXACT [] synonym: "juvenile hormone synthesis" EXACT [] is_a: GO:0006716 ! juvenile hormone metabolic process -is_a: GO:0016106 ! sesquiterpenoid biosynthetic process +is_a: GO:0009058 ! biosynthetic process is_a: GO:0042446 ! hormone biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:24943 ! juvenile hormone -relationship: has_primary_output CHEBI:24943 ! juvenile hormone +intersection_of: has_primary_output CHEBI:24943 +relationship: has_primary_output CHEBI:24943 [Term] id: GO:0006719 @@ -60133,38 +49018,10 @@ synonym: "juvenile hormone breakdown" EXACT [] synonym: "juvenile hormone catabolism" EXACT [] synonym: "juvenile hormone degradation" EXACT [] is_a: GO:0006716 ! juvenile hormone metabolic process -is_a: GO:0016107 ! sesquiterpenoid catabolic process is_a: GO:0042447 ! hormone catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:24943 ! juvenile hormone -relationship: has_primary_input CHEBI:24943 ! juvenile hormone - -[Term] -id: GO:0006720 -name: isoprenoid metabolic process -namespace: biological_process -alt_id: GO:0016096 -def: "The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." [ISBN:0198547684] -synonym: "isoprenoid metabolism" EXACT [] -synonym: "polyisoprenoid metabolic process" NARROW [] -synonym: "polyisoprenoid metabolism" NARROW [] -synonym: "polyterpene metabolic process" NARROW [] -synonym: "polyterpene metabolism" NARROW [] -is_a: GO:0044255 ! cellular lipid metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:24913 ! isoprenoid -relationship: has_primary_input_or_output CHEBI:24913 ! isoprenoid - -[Term] -id: GO:0006721 -name: terpenoid metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups." [ISBN:0198506732] -synonym: "terpenoid metabolism" EXACT [] -is_a: GO:0006720 ! isoprenoid metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:26873 ! terpenoid -relationship: has_primary_input_or_output CHEBI:26873 ! terpenoid +intersection_of: has_primary_input CHEBI:24943 +relationship: has_primary_input CHEBI:24943 [Term] id: GO:0006725 @@ -60177,40 +49034,8 @@ synonym: "aromatic hydrocarbon metabolic process" NARROW [] synonym: "aromatic hydrocarbon metabolism" NARROW [] is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:33655 ! aromatic compound -relationship: has_primary_input_or_output CHEBI:33655 ! aromatic compound - -[Term] -id: GO:0006790 -name: sulfur compound metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:ai] -subset: goslim_chembl -subset: goslim_drosophila -subset: goslim_generic -subset: goslim_pir -subset: goslim_pombe -subset: prokaryote_subset -synonym: "sulfur metabolism" EXACT [] -synonym: "sulphur metabolic process" EXACT [] -synonym: "sulphur metabolism" EXACT [] -xref: Wikipedia:Sulfur_metabolism -is_a: GO:0044237 ! cellular metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:26835 ! sulfur molecular entity -relationship: has_primary_input_or_output CHEBI:26835 ! sulfur molecular entity - -[Term] -id: GO:0006793 -name: phosphorus metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)." [GOC:ai] -subset: goslim_pir -synonym: "phosphorus metabolism" EXACT [] -is_a: GO:0044237 ! cellular metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:26082 ! phosphorus molecular entity -relationship: has_primary_input_or_output CHEBI:26082 ! phosphorus molecular entity +intersection_of: has_primary_input_or_output CHEBI:33655 +relationship: has_primary_input_or_output CHEBI:33655 [Term] id: GO:0006796 @@ -60219,10 +49044,10 @@ namespace: biological_process def: "The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid." [GOC:ai] synonym: "phosphate metabolic process" RELATED [] synonym: "phosphate metabolism" EXACT [] -is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:26020 ! phosphate -relationship: has_primary_input_or_output CHEBI:26020 ! phosphate +intersection_of: has_primary_input_or_output CHEBI:26020 +relationship: has_primary_input_or_output CHEBI:26020 [Term] id: GO:0006801 @@ -60234,10 +49059,10 @@ synonym: "oxygen free radical metabolism" EXACT [] synonym: "superoxide free radical metabolic process" EXACT [] synonym: "superoxide free radical metabolism" EXACT [] synonym: "superoxide metabolism" EXACT [] -is_a: GO:0072593 ! reactive oxygen species metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:18421 ! superoxide -relationship: has_primary_input_or_output CHEBI:18421 ! superoxide +intersection_of: has_primary_input_or_output CHEBI:18421 +relationship: has_primary_input_or_output CHEBI:18421 [Term] id: GO:0006807 @@ -60249,8 +49074,8 @@ subset: goslim_pir synonym: "nitrogen compound metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:51143 ! nitrogen molecular entity -relationship: has_primary_input_or_output CHEBI:51143 ! nitrogen molecular entity +intersection_of: has_primary_input_or_output CHEBI:51143 +relationship: has_primary_input_or_output CHEBI:51143 [Term] id: GO:0006809 @@ -60264,8 +49089,8 @@ synonym: "nitric oxide synthesis" EXACT [] is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process is_a: GO:0046209 ! nitric oxide metabolic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:16480 ! nitric oxide -relationship: has_primary_output CHEBI:16480 ! nitric oxide +intersection_of: has_primary_output CHEBI:16480 +relationship: has_primary_output CHEBI:16480 [Term] id: GO:0006810 @@ -60300,8 +49125,8 @@ subset: goslim_yeast synonym: "ion transport" BROAD [] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion -relationship: has_primary_input CHEBI:24867 ! monoatomic ion +intersection_of: has_primary_input CHEBI:24867 +relationship: has_primary_input CHEBI:24867 [Term] id: GO:0006812 @@ -60314,28 +49139,10 @@ def: "The directed movement of a monoatomic cation, into, out of or within a cel synonym: "cation transport" BROAD [] synonym: "di-, tri-valent inorganic cation transport" NARROW [GOC:mah] synonym: "trivalent inorganic cation transport" NARROW [] -is_a: GO:0006811 ! monoatomic ion transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation -relationship: has_primary_input CHEBI:23906 ! monoatomic cation - -[Term] -id: GO:0006814 -name: sodium ion transport -namespace: biological_process -alt_id: GO:0006834 -alt_id: GO:0016974 -def: "The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] -synonym: "mitochondrial sodium/calcium ion exchange" NARROW [] -synonym: "sodium channel auxiliary protein activity" RELATED [GOC:mah] -synonym: "sodium transport" EXACT [] -synonym: "sodium/potassium transport" BROAD [] -synonym: "sodium:calcium exchange" NARROW [] -synonym: "sodium:solute transport" NARROW [] -is_a: GO:0030001 ! metal ion transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:29101 ! sodium(1+) -relationship: has_primary_input CHEBI:29101 ! sodium(1+) +intersection_of: has_primary_input CHEBI:23906 +relationship: has_primary_input CHEBI:23906 [Term] id: GO:0006816 @@ -60345,21 +49152,10 @@ def: "The directed movement of calcium (Ca) ions into, out of or within a cell, synonym: "calcium transport" EXACT [] synonym: "mitochondrial sodium/calcium ion exchange" NARROW [] synonym: "sodium:calcium exchange" NARROW [] -is_a: GO:0030001 ! metal ion transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:29108 ! calcium(2+) -relationship: has_primary_input CHEBI:29108 ! calcium(2+) - -[Term] -id: GO:0006817 -name: phosphate ion transport -namespace: biological_process -def: "The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] -synonym: "phosphate transport" RELATED [] -is_a: GO:0015698 ! inorganic anion transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:35780 ! phosphate ion -relationship: has_primary_input CHEBI:35780 ! phosphate ion +intersection_of: has_primary_input CHEBI:29108 +relationship: has_primary_input CHEBI:29108 [Term] id: GO:0006826 @@ -60380,10 +49176,10 @@ synonym: "ferrous ion transport" NARROW [] synonym: "ferrous iron transport" NARROW [] synonym: "iron ion import" RELATED [] synonym: "iron transport" EXACT [] -is_a: GO:0000041 ! transition metal ion transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:24875 ! iron cation -relationship: has_primary_input CHEBI:24875 ! iron cation +intersection_of: has_primary_input CHEBI:24875 +relationship: has_primary_input CHEBI:24875 created_by: pr creation_date: 2012-04-18T03:33:45Z @@ -60394,8 +49190,8 @@ namespace: biological_process def: "The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0042044 ! fluid transport intersection_of: GO:0042044 ! fluid transport -intersection_of: has_primary_input CHEBI:15377 ! water -relationship: has_primary_input CHEBI:15377 ! water +intersection_of: has_primary_input CHEBI:15377 +relationship: has_primary_input CHEBI:15377 [Term] id: GO:0006835 @@ -60404,10 +49200,10 @@ namespace: biological_process alt_id: GO:0006841 def: "The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] synonym: "sodium:dicarboxylate transport" RELATED [] -is_a: GO:0046942 ! carboxylic acid transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:35693 ! dicarboxylic acid anion -relationship: has_primary_input CHEBI:35693 ! dicarboxylic acid anion +intersection_of: has_primary_input CHEBI:35693 +relationship: has_primary_input CHEBI:35693 [Term] id: GO:0006836 @@ -60425,31 +49221,10 @@ id: GO:0006837 name: serotonin transport namespace: biological_process def: "The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems." [GOC:ai] -is_a: GO:0071705 ! nitrogen compound transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:350546 ! serotonin(1+) -relationship: has_primary_input CHEBI:350546 ! serotonin(1+) - -[Term] -id: GO:0006846 -name: acetate transport -namespace: biological_process -def: "The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] -is_a: GO:0015718 ! monocarboxylic acid transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:30089 ! acetate -relationship: has_primary_input CHEBI:30089 ! acetate - -[Term] -id: GO:0006847 -name: plasma membrane acetate transport -namespace: biological_process -def: "The directed movement of acetate across a plasma membrane." [GOC:ai] -is_a: GO:0035433 ! acetate transmembrane transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:30089 ! acetate -intersection_of: results_in_transport_across GO:0005886 ! plasma membrane -relationship: results_in_transport_across GO:0005886 ! plasma membrane +intersection_of: has_primary_input CHEBI:350546 +relationship: has_primary_input CHEBI:350546 [Term] id: GO:0006858 @@ -60479,11 +49254,10 @@ alt_id: GO:0006866 def: "The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_pir subset: goslim_yeast -is_a: GO:0015849 ! organic acid transport -is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:33709 ! amino acid -relationship: has_primary_input CHEBI:33709 ! amino acid +intersection_of: has_primary_input CHEBI:33709 +relationship: has_primary_input CHEBI:33709 [Term] id: GO:0006869 @@ -60493,10 +49267,10 @@ def: "The directed movement of lipids into, out of or within a cell, or between subset: goslim_drosophila subset: goslim_pir subset: goslim_yeast -is_a: GO:0071702 ! organic substance transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:18059 ! lipid -relationship: has_primary_input CHEBI:18059 ! lipid +intersection_of: has_primary_input CHEBI:18059 +relationship: has_primary_input CHEBI:18059 relationship: part_of GO:0010876 ! lipid localization [Term] @@ -60507,10 +49281,10 @@ def: "A homeostatic process involved in the maintenance of a steady state level subset: goslim_yeast synonym: "cellular ion homeostasis" BROAD [] synonym: "cellular monoatomic ion homeostasis" EXACT [] -is_a: GO:0050801 ! monoatomic ion homeostasis -is_a: GO:0055082 ! intracellular chemical homeostasis +is_a: GO:0019725 ! cellular homeostasis intersection_of: GO:0019725 ! cellular homeostasis -intersection_of: regulates_levels_of CHEBI:24867 ! monoatomic ion +intersection_of: regulates_levels_of CHEBI:24867 +relationship: regulates_levels_of CHEBI:24867 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24455" xsd:anyURI [Term] @@ -60520,10 +49294,10 @@ namespace: biological_process def: "A homeostatic process involved in the maintenance of a steady state level of calcium ions within a cell." [GOC:ceb, GOC:mah] synonym: "cellular calcium ion homeostasis" EXACT [] synonym: "regulation of calcium ion concentration" BROAD [] -is_a: GO:0030003 ! intracellular monoatomic cation homeostasis -is_a: GO:0055074 ! calcium ion homeostasis +is_a: GO:0019725 ! cellular homeostasis intersection_of: GO:0019725 ! cellular homeostasis -intersection_of: regulates_levels_of CHEBI:29108 ! calcium(2+) +intersection_of: regulates_levels_of CHEBI:29108 +relationship: regulates_levels_of CHEBI:29108 [Term] id: GO:0006879 @@ -60532,21 +49306,10 @@ namespace: biological_process def: "A homeostatic process involved in the maintenance of a steady state level of iron ions within a cell." [GOC:ai, GOC:mah] synonym: "cellular iron ion homeostasis" EXACT [] synonym: "iron homeostasis" BROAD [] -is_a: GO:0030003 ! intracellular monoatomic cation homeostasis -is_a: GO:0055072 ! iron ion homeostasis -intersection_of: GO:0055082 ! intracellular chemical homeostasis -intersection_of: regulates_levels_of CHEBI:24875 ! iron cation - -[Term] -id: GO:0006883 -name: intracellular sodium ion homeostasis -namespace: biological_process -def: "A homeostatic process involved in the maintenance of a steady state level of sodium ions within a cell." [GOC:ai, GOC:mah] -synonym: "cellular sodium ion homeostasis" EXACT [] -is_a: GO:0030003 ! intracellular monoatomic cation homeostasis -is_a: GO:0055078 ! sodium ion homeostasis +is_a: GO:0055082 ! intracellular chemical homeostasis intersection_of: GO:0055082 ! intracellular chemical homeostasis -intersection_of: regulates_levels_of CHEBI:29101 ! sodium(1+) +intersection_of: regulates_levels_of CHEBI:24875 +relationship: regulates_levels_of CHEBI:24875 [Term] id: GO:0006884 @@ -60633,7 +49396,7 @@ namespace: biological_process alt_id: GO:0016193 alt_id: GO:0016196 alt_id: GO:0098701 -def: "A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." [GOC:mah, ISBN:0198506732, ISBN:0716731363] +def: "A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle." [GOC:mah, ISBN:0198506732, ISBN:0716731363, Wikipedia:Endocytosis] subset: goslim_yeast synonym: "endocytic import into cell" EXACT [] synonym: "nonselective vesicle endocytosis" RELATED [] @@ -60648,6 +49411,7 @@ relationship: has_part GO:0010324 ! membrane invagination relationship: has_target_end_location GO:0031410 ! cytoplasmic vesicle relationship: has_target_start_location GO:0005576 ! extracellular region relationship: process_has_causal_agent GO:0030139 ! endocytic vesicle +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24907" xsd:anyURI [Term] id: GO:0006900 @@ -60696,8 +49460,9 @@ name: phagocytosis namespace: biological_process def: "A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles." [ISBN:0198506732] xref: Wikipedia:Phagocytosis -is_a: GO:0016192 ! vesicle-mediated transport +is_a: GO:0006897 ! endocytosis relationship: never_in_taxon NCBITaxon:4751 ! Fungi +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24907" xsd:anyURI [Term] id: GO:0006914 @@ -60915,14 +49680,6 @@ def: "An immune response mediated through a body fluid." [GOC:hb, ISBN:019850673 xref: Wikipedia:Humoral_immunity is_a: GO:0006955 ! immune response -[Term] -id: GO:0006979 -name: response to oxidative stress -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:jl, PMID:12115731] -subset: goslim_yeast -is_a: GO:0006950 ! response to stress - [Term] id: GO:0006996 name: organelle organization @@ -61179,6 +49936,8 @@ name: vacuolar calcium ion homeostasis namespace: biological_process def: "Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings." [GOC:ai, GOC:mah] is_a: GO:0006874 ! intracellular calcium ion homeostasis +is_a: GO:0055074 ! calcium ion homeostasis +is_a: GO:0055082 ! intracellular chemical homeostasis intersection_of: GO:0055074 ! calcium ion homeostasis intersection_of: occurs_in GO:0005773 ! vacuole relationship: occurs_in GO:0005773 ! vacuole @@ -61687,7 +50446,7 @@ namespace: biological_process def: "The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:dos, Wikipedia:Cholinergic] synonym: "cholinergic synaptic transmission" EXACT [] is_a: GO:0007268 ! chemical synaptic transmission -relationship: has_participant CHEBI:15355 ! acetylcholine +relationship: has_participant CHEBI:15355 [Term] id: GO:0007272 @@ -62498,7 +51257,6 @@ namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females." [ISBN:0198506732] synonym: "regulation of ecdysteroid metabolism" EXACT [] is_a: GO:0010565 ! regulation of cellular ketone metabolic process -is_a: GO:0019218 ! regulation of steroid metabolic process is_a: GO:0032350 ! regulation of hormone metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045455 ! ecdysteroid metabolic process @@ -62536,7 +51294,6 @@ name: regulation of juvenile hormone metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone." [GOC:go_curators] synonym: "regulation of juvenile hormone metabolism" EXACT [] -is_a: GO:0019747 ! regulation of isoprenoid metabolic process is_a: GO:0032350 ! regulation of hormone metabolic process is_a: GO:0043455 ! regulation of secondary metabolic process intersection_of: GO:0065007 ! biological regulation @@ -62555,7 +51312,6 @@ synonym: "regulation of juvenile hormone formation" EXACT [] synonym: "regulation of juvenile hormone synthesis" EXACT [] is_a: GO:0007556 ! regulation of juvenile hormone metabolic process is_a: GO:0046885 ! regulation of hormone biosynthetic process -is_a: GO:0046890 ! regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006718 ! juvenile hormone biosynthetic process relationship: regulates GO:0006718 ! juvenile hormone biosynthetic process @@ -62565,7 +51321,6 @@ id: GO:0007558 name: regulation of juvenile hormone secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of juvenile hormone secretion." [GOC:go_curators] -is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0044060 ! regulation of endocrine process is_a: GO:0046883 ! regulation of hormone secretion intersection_of: GO:0065007 ! biological regulation @@ -62839,24 +51594,6 @@ intersection_of: GO:0005488 ! binding intersection_of: has_input GO:0005874 ! microtubule relationship: has_input GO:0005874 ! microtubule -[Term] -id: GO:0008028 -name: monocarboxylic acid transmembrane transporter activity -namespace: molecular_function -alt_id: GO:0008505 -def: "Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group." [GOC:ai] -synonym: "monocarboxylate carrier" NARROW [] -synonym: "prostaglandin/thromboxane transporter activity" NARROW [] -xref: Reactome:R-HSA-429749 "SLC5A8 transports monocarboxylates from extracellular region to cytosol" -xref: Reactome:R-HSA-433698 "SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol" -xref: Reactome:R-HSA-5624211 "Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol" -xref: Reactome:R-HSA-9645220 "SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol" -is_a: GO:0005342 ! organic acid transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:25384 ! monocarboxylic acid -relationship: has_primary_input CHEBI:25384 ! monocarboxylic acid -relationship: part_of GO:0015718 ! monocarboxylic acid transport - [Term] id: GO:0008047 name: enzyme activator activity @@ -62878,8 +51615,8 @@ namespace: molecular_function def: "Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:ai, GOC:signaling] is_a: GO:0004888 ! transmembrane signaling receptor activity intersection_of: GO:0038023 ! signaling receptor activity -intersection_of: has_input CHEBI:14321 ! glutamate(1-) -relationship: has_input CHEBI:14321 ! glutamate(1-) +intersection_of: has_input CHEBI:14321 +relationship: has_input CHEBI:14321 relationship: has_part GO:0016595 ! glutamate binding [Term] @@ -63021,7 +51758,7 @@ namespace: biological_process alt_id: GO:0000004 alt_id: GO:0007582 alt_id: GO:0044699 -def: "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." [GOC:pdt] +def: "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." [GOC:pdt] comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl @@ -63036,6 +51773,7 @@ synonym: "single organism process" RELATED [] synonym: "single-organism process" RELATED [] xref: Wikipedia:Biological_process is_a: BFO:0000015 ! process +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24968" xsd:anyURI created_by: jl creation_date: 2012-09-19T15:05:24Z @@ -63075,8 +51813,8 @@ synonym: "RNA-dependent adenosinetriphosphatase activity" EXACT [] synonym: "RNA-dependent ATPase activity" EXACT [] is_a: GO:0140657 ! ATP-dependent activity intersection_of: GO:0140657 ! ATP-dependent activity -intersection_of: has_input CHEBI:33697 ! ribonucleic acid -relationship: has_input CHEBI:33697 ! ribonucleic acid +intersection_of: has_input CHEBI:33697 +relationship: has_input CHEBI:33697 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20876" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21775" xsd:anyURI @@ -63108,11 +51846,10 @@ name: heparin binding namespace: molecular_function def: "Binding to heparin, a member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues." [GOC:jl, ISBN:0198506732] synonym: "heparan sulfate binding" RELATED [] -is_a: GO:0005539 ! glycosaminoglycan binding -is_a: GO:1901681 ! sulfur compound binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:24505 ! heparins -relationship: has_input CHEBI:24505 ! heparins +intersection_of: has_input CHEBI:24505 +relationship: has_input CHEBI:24505 [Term] id: GO:0008202 @@ -63124,8 +51861,8 @@ xref: Wikipedia:Steroid_metabolism is_a: GO:0006629 ! lipid metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:35341 ! steroid -relationship: has_primary_input_or_output CHEBI:35341 ! steroid +intersection_of: has_primary_input_or_output CHEBI:35341 +relationship: has_primary_input_or_output CHEBI:35341 [Term] id: GO:0008206 @@ -63137,8 +51874,8 @@ is_a: GO:0008202 ! steroid metabolic process is_a: GO:0032787 ! monocarboxylic acid metabolic process is_a: GO:1901615 ! organic hydroxy compound metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:36235 ! bile acid anion -relationship: has_primary_input_or_output CHEBI:36235 ! bile acid anion +intersection_of: has_primary_input_or_output CHEBI:36235 +relationship: has_primary_input_or_output CHEBI:36235 [Term] id: GO:0008207 @@ -63150,8 +51887,8 @@ is_a: GO:0008202 ! steroid metabolic process is_a: GO:0009987 ! cellular process is_a: GO:0042445 ! hormone metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:64600 ! C21-steroid hormone -relationship: has_primary_input_or_output CHEBI:64600 ! C21-steroid hormone +intersection_of: has_primary_input_or_output CHEBI:64600 +relationship: has_primary_input_or_output CHEBI:64600 [Term] id: GO:0008208 @@ -63161,12 +51898,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of C21-ster synonym: "C21-steroid hormone breakdown" EXACT [] synonym: "C21-steroid hormone catabolism" EXACT [] synonym: "C21-steroid hormone degradation" EXACT [] -is_a: GO:0006706 ! steroid catabolic process is_a: GO:0008207 ! C21-steroid hormone metabolic process is_a: GO:0042447 ! hormone catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:64600 ! C21-steroid hormone -relationship: has_primary_input CHEBI:64600 ! C21-steroid hormone +intersection_of: has_primary_input CHEBI:64600 +relationship: has_primary_input CHEBI:64600 [Term] id: GO:0008211 @@ -63178,8 +51914,8 @@ synonym: "glucocorticosteroid metabolic process" EXACT [] synonym: "glucocorticosteroid metabolism" EXACT [] is_a: GO:0008202 ! steroid metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:24261 ! glucocorticoid -relationship: has_primary_input_or_output CHEBI:24261 ! glucocorticoid +intersection_of: has_primary_input_or_output CHEBI:24261 +relationship: has_primary_input_or_output CHEBI:24261 [Term] id: GO:0008212 @@ -63191,8 +51927,8 @@ is_a: GO:0008202 ! steroid metabolic process is_a: GO:0009987 ! cellular process is_a: GO:0042445 ! hormone metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:25354 ! mineralocorticoid -relationship: has_primary_input_or_output CHEBI:25354 ! mineralocorticoid +intersection_of: has_primary_input_or_output CHEBI:25354 +relationship: has_primary_input_or_output CHEBI:25354 [Term] id: GO:0008217 @@ -63212,11 +51948,6 @@ name: cell death namespace: biological_process def: "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." [GOC:mah, GOC:mtg_apoptosis, PMID:25236395] comment: This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term. -subset: goslim_agr -subset: goslim_chembl -subset: goslim_drosophila -subset: goslim_mouse -subset: goslim_plant synonym: "accidental cell death" RELATED [] synonym: "necrosis" RELATED [] is_a: GO:0009987 ! cellular process @@ -63231,8 +51962,8 @@ synonym: "biogenic amine receptor" NARROW [] synonym: "G-protein coupled amine receptor activity" EXACT [] is_a: GO:0004930 ! G protein-coupled receptor activity intersection_of: GO:0004930 ! G protein-coupled receptor activity -intersection_of: has_input CHEBI:32952 ! amine -relationship: has_input CHEBI:32952 ! amine +intersection_of: has_input CHEBI:32952 +relationship: has_input CHEBI:32952 [Term] id: GO:0008233 @@ -63284,19 +52015,6 @@ xref: Reactome:R-HSA-2467809 "ESPL1 (Separase) cleaves centromeric cohesin" xref: Reactome:R-HSA-5660752 "USP9X deubiquitinates Ub-SNCA" is_a: GO:0008233 ! peptidase activity -[Term] -id: GO:0008272 -name: sulfate transport -namespace: biological_process -alt_id: GO:0006870 -def: "The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] -synonym: "sulphate transport" EXACT [] -is_a: GO:0015698 ! inorganic anion transport -is_a: GO:0072348 ! sulfur compound transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:16189 ! sulfate -relationship: has_primary_input CHEBI:16189 ! sulfate - [Term] id: GO:0008277 name: regulation of G protein-coupled receptor signaling pathway @@ -63395,8 +52113,8 @@ subset: goslim_yeast subset: prokaryote_subset is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:18059 ! lipid -relationship: has_input CHEBI:18059 ! lipid +intersection_of: has_input CHEBI:18059 +relationship: has_input CHEBI:18059 [Term] id: GO:0008291 @@ -63404,12 +52122,10 @@ name: acetylcholine metabolic process namespace: biological_process def: "The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:jl, GOC:nln, ISBN:0192800752] synonym: "acetylcholine metabolism" EXACT [] -is_a: GO:0006807 ! nitrogen compound metabolic process is_a: GO:0042133 ! neurotransmitter metabolic process -is_a: GO:1900619 ! acetate ester metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:15355 ! acetylcholine -relationship: has_primary_input_or_output CHEBI:15355 ! acetylcholine +intersection_of: has_primary_input_or_output CHEBI:15355 +relationship: has_primary_input_or_output CHEBI:15355 [Term] id: GO:0008292 @@ -63422,56 +52138,9 @@ synonym: "acetylcholine formation" EXACT [] synonym: "acetylcholine synthesis" EXACT [] is_a: GO:0008291 ! acetylcholine metabolic process is_a: GO:0042136 ! neurotransmitter biosynthetic process -is_a: GO:1900620 ! acetate ester biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:15355 ! acetylcholine -relationship: has_primary_output CHEBI:15355 ! acetylcholine - -[Term] -id: GO:0008299 -name: isoprenoid biosynthetic process -namespace: biological_process -alt_id: GO:0009241 -def: "The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." [ISBN:0198506732] -synonym: "isoprenoid anabolism" EXACT [] -synonym: "isoprenoid biosynthesis" EXACT [] -synonym: "isoprenoid formation" EXACT [] -synonym: "isoprenoid synthesis" EXACT [] -synonym: "polyisoprenoid anabolism" NARROW [] -synonym: "polyisoprenoid biosynthesis" NARROW [] -synonym: "polyisoprenoid biosynthetic process" NARROW [] -synonym: "polyisoprenoid formation" NARROW [] -synonym: "polyisoprenoid synthesis" NARROW [] -synonym: "polyterpene biosynthesis" NARROW [] -synonym: "polyterpene biosynthetic process" NARROW [] -xref: MetaCyc:POLYISOPRENSYN-PWY -is_a: GO:0006720 ! isoprenoid metabolic process -is_a: GO:0008610 ! lipid biosynthetic process -is_a: GO:0044249 ! cellular biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:24913 ! isoprenoid -relationship: has_primary_output CHEBI:24913 ! isoprenoid - -[Term] -id: GO:0008300 -name: isoprenoid catabolic process -namespace: biological_process -alt_id: GO:0016097 -def: "The chemical reactions and pathways resulting in the breakdown of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." [ISBN:0198506732] -synonym: "isoprenoid breakdown" EXACT [] -synonym: "isoprenoid catabolism" EXACT [] -synonym: "isoprenoid degradation" EXACT [] -synonym: "polyisoprenoid breakdown" NARROW [] -synonym: "polyisoprenoid catabolic process" NARROW [] -synonym: "polyisoprenoid catabolism" NARROW [] -synonym: "polyisoprenoid degradation" NARROW [] -synonym: "polyterpene catabolic process" NARROW [] -synonym: "polyterpene catabolism" NARROW [] -is_a: GO:0006720 ! isoprenoid metabolic process -is_a: GO:0044242 ! cellular lipid catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:24913 ! isoprenoid -relationship: has_primary_input CHEBI:24913 ! isoprenoid +intersection_of: has_primary_output CHEBI:15355 +relationship: has_primary_output CHEBI:15355 [Term] id: GO:0008320 @@ -63501,7 +52170,7 @@ xref: Reactome:R-HSA-5336420 "DT fragment B transports DT fragment A from target xref: Reactome:R-HSA-9636375 "SecA2 transports SapM from cytoplasm to cytosol" xref: Reactome:R-HSA-9698930 "HCMV C Nucleocapsid Translocation" xref: Reactome:R-HSA-9698933 "HCMV B Nucleocapsid Translocation" -is_a: GO:0022884 ! macromolecule transmembrane transporter activity +is_a: GO:0022857 ! transmembrane transporter activity is_a: GO:0140318 ! protein transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: has_primary_input PR:000000001 ! protein @@ -63515,10 +52184,10 @@ namespace: molecular_function def: "Enables the transfer of cation from one side of a membrane to the other." [GOC:dgf, GOC:mtg_transport, ISBN:0815340729] synonym: "cation transmembrane transporter activity" BROAD [] synonym: "transmembrane cation transporter activity" EXACT [] -is_a: GO:0015075 ! monoatomic ion transmembrane transporter activity +is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation -relationship: has_primary_input CHEBI:23906 ! monoatomic cation +intersection_of: has_primary_input CHEBI:23906 +relationship: has_primary_input CHEBI:23906 relationship: part_of GO:0098655 ! monoatomic cation transmembrane transport property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI @@ -63621,38 +52290,8 @@ namespace: molecular_function def: "Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin." [GOC:ai, ISBN:0198506732] is_a: GO:0004930 ! G protein-coupled receptor activity intersection_of: GO:0038023 ! signaling receptor activity -intersection_of: has_input CHEBI:16796 ! melatonin -relationship: has_input CHEBI:16796 ! melatonin - -[Term] -id: GO:0008504 -name: monoamine transmembrane transporter activity -namespace: molecular_function -alt_id: GO:0015201 -def: "Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other." [GOC:mah] -xref: Reactome:R-HSA-372542 "Loading of dopamine into synaptic veiscles" -xref: Reactome:R-HSA-379393 "SLC6A3 cotransports DA, Na+ from extracellular region to cytosol" -xref: Reactome:R-HSA-380586 "loading of Serotonin in synaptic vesicles" -xref: Reactome:R-HSA-380620 "Reuptake of serotonin from the synapse" -xref: Reactome:R-HSA-444160 "VMAT1/2 can mediate the transport of biogenic amines" -xref: Reactome:R-HSA-5660706 "Defective SLC6A3 does not cotransport DA, Na+ from extracellular region to cytosol" -is_a: GO:0022804 ! active transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:63534 ! monoamine -relationship: has_primary_input CHEBI:63534 ! monoamine -relationship: part_of GO:0015844 ! monoamine transport - -[Term] -id: GO:0008514 -name: organic anion transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." [GOC:ai] -xref: Reactome:R-HSA-2142859 "Growing HA is extruded from the cell by ABCC5" -is_a: GO:0022857 ! transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:25696 ! organic anion -relationship: has_primary_input CHEBI:25696 ! organic anion -relationship: part_of GO:0015711 ! organic anion transport +intersection_of: has_input CHEBI:16796 +relationship: has_input CHEBI:16796 [Term] id: GO:0008519 @@ -63672,11 +52311,10 @@ xref: Reactome:R-HSA-5623051 "Defective RHAG does not transport NH4+ from cytoso xref: RHEA:28747 xref: TC:1.A.11 {http://purl.obolibrary.org/obo/IAO_0000233="https://github.com/geneontology/go-ontology/issues/23129"} is_a: GO:0015267 ! channel activity -is_a: GO:0022890 ! inorganic cation transmembrane transporter activity intersection_of: GO:0015267 ! channel activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:28938 ! ammonium -relationship: has_primary_input CHEBI:28938 ! ammonium +intersection_of: has_primary_input CHEBI:28938 +relationship: has_primary_input CHEBI:28938 relationship: part_of GO:0072488 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! ammonium transmembrane transport property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22368" xsd:anyURI @@ -63764,8 +52402,8 @@ synonym: "lipogenesis" EXACT [GOC:sl] is_a: GO:0006629 ! lipid metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:18059 ! lipid -relationship: has_primary_output CHEBI:18059 ! lipid +intersection_of: has_primary_output CHEBI:18059 +relationship: has_primary_output CHEBI:18059 [Term] id: GO:0008641 @@ -63790,10 +52428,10 @@ def: "The directed movement of carbohydrate into, out of or within a cell, or be subset: goslim_pir subset: goslim_yeast synonym: "sugar transport" NARROW [] -is_a: GO:0071702 ! organic substance transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:16646 ! carbohydrate -relationship: has_primary_input CHEBI:16646 ! carbohydrate +intersection_of: has_primary_input CHEBI:16646 +relationship: has_primary_input CHEBI:16646 [Term] id: GO:0008645 @@ -63808,11 +52446,11 @@ synonym: "hexose membrane transport" RELATED [] synonym: "hexose transport" RELATED [] synonym: "high-affinity hexose transport" NARROW [] synonym: "low-affinity hexose transport" NARROW [] -is_a: GO:0015749 ! monosaccharide transmembrane transport +is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:18133 ! hexose +intersection_of: has_primary_input CHEBI:18133 intersection_of: results_in_transport_across GO:0016020 ! membrane -relationship: has_primary_input CHEBI:18133 ! hexose +relationship: has_primary_input CHEBI:18133 created_by: bf creation_date: 2010-04-08T10:27:23Z @@ -63828,11 +52466,10 @@ synonym: "amino acid synthesis" EXACT [] synonym: "cellular amino acid biosynthetic process" EXACT [] xref: Wikipedia:Amino_acid_synthesis is_a: GO:0006520 ! amino acid metabolic process -is_a: GO:0046394 ! carboxylic acid biosynthetic process -is_a: GO:1901566 ! organonitrogen compound biosynthetic process +is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:37022 ! amino-acid anion -relationship: has_primary_output CHEBI:37022 ! amino-acid anion +intersection_of: has_primary_output CHEBI:37022 +relationship: has_primary_output CHEBI:37022 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI [Term] @@ -63864,15 +52501,18 @@ alt_id: GO:0044266 def: "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] subset: goslim_pir synonym: "biopolymer catabolic process" EXACT [GOC:mtg_chebi_dec09] +synonym: "cellular macromolecule catabolic process" RELATED [] +synonym: "cellular macromolecule catabolism" RELATED [] +synonym: "cellular macromolecule degradation" RELATED [] synonym: "macromolecule breakdown" EXACT [] synonym: "macromolecule catabolism" EXACT [] synonym: "macromolecule degradation" EXACT [] synonym: "multicellular organismal macromolecule catabolic process" NARROW [] +is_a: GO:0009056 ! catabolic process is_a: GO:0043170 ! macromolecule metabolic process -is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:33694 ! biomacromolecule -relationship: has_primary_input CHEBI:33694 ! biomacromolecule +intersection_of: has_primary_input CHEBI:33694 +relationship: has_primary_input CHEBI:33694 [Term] id: GO:0009058 @@ -63910,24 +52550,9 @@ synonym: "macromolecule synthesis" EXACT [] is_a: GO:0043170 ! macromolecule metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:33694 ! biomacromolecule -relationship: has_primary_output CHEBI:33694 ! biomacromolecule - -[Term] -id: GO:0009062 -name: fatty acid catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes." [GOC:go_curators] -synonym: "fatty acid breakdown" EXACT [] -synonym: "fatty acid catabolism" EXACT [] -synonym: "fatty acid degradation" EXACT [] -xref: Wikipedia:Fatty_acid_degradation -is_a: GO:0006631 ! fatty acid metabolic process -is_a: GO:0044242 ! cellular lipid catabolic process -is_a: GO:0072329 ! monocarboxylic acid catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:28868 ! fatty acid anion -relationship: has_primary_input CHEBI:28868 ! fatty acid anion +intersection_of: has_primary_output CHEBI:33694 +relationship: has_primary_output CHEBI:33694 +property_value: IAO:0000233 "http://amigo.geneontology.org/amigo/term/GO:0070589" xsd:anyURI [Term] id: GO:0009063 @@ -63939,11 +52564,10 @@ synonym: "amino acid catabolism" EXACT [] synonym: "amino acid degradation" EXACT [] synonym: "cellular amino acid catabolic process" EXACT [] is_a: GO:0006520 ! amino acid metabolic process -is_a: GO:0046395 ! carboxylic acid catabolic process -is_a: GO:1901565 ! organonitrogen compound catabolic process +is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:37022 ! amino-acid anion -relationship: has_primary_input CHEBI:37022 ! amino-acid anion +intersection_of: has_primary_input CHEBI:37022 +relationship: has_primary_input CHEBI:37022 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI [Term] @@ -63954,8 +52578,8 @@ def: "The chemical reactions and pathways involving amino acids of the glutamine synonym: "glutamine family amino acid metabolism" EXACT [] is_a: GO:1901605 ! alpha-amino acid metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:24318 ! glutamine family amino acid -relationship: has_primary_input_or_output CHEBI:24318 ! glutamine family amino acid +intersection_of: has_primary_input_or_output CHEBI:24318 +relationship: has_primary_input_or_output CHEBI:24318 [Term] id: GO:0009065 @@ -63965,12 +52589,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of amino ac synonym: "glutamine family amino acid breakdown" EXACT [] synonym: "glutamine family amino acid catabolism" EXACT [] synonym: "glutamine family amino acid degradation" EXACT [] +is_a: GO:0009056 ! catabolic process is_a: GO:0009064 ! glutamine family amino acid metabolic process -is_a: GO:0016054 ! organic acid catabolic process -is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:24318 ! glutamine family amino acid -relationship: has_primary_input CHEBI:24318 ! glutamine family amino acid +intersection_of: has_primary_input CHEBI:24318 +relationship: has_primary_input CHEBI:24318 [Term] id: GO:0009069 @@ -63978,11 +52601,10 @@ name: serine family amino acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine." [GOC:ai] synonym: "serine family amino acid metabolism" EXACT [] -is_a: GO:0006082 ! organic acid metabolic process -is_a: GO:1901564 ! organonitrogen compound metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:26650 ! serine family amino acid -relationship: has_primary_input_or_output CHEBI:26650 ! serine family amino acid +intersection_of: has_primary_input_or_output CHEBI:26650 +relationship: has_primary_input_or_output CHEBI:26650 [Term] id: GO:0009070 @@ -63993,12 +52615,11 @@ synonym: "serine family amino acid anabolism" EXACT [] synonym: "serine family amino acid biosynthesis" EXACT [] synonym: "serine family amino acid formation" EXACT [] synonym: "serine family amino acid synthesis" EXACT [] +is_a: GO:0009058 ! biosynthetic process is_a: GO:0009069 ! serine family amino acid metabolic process -is_a: GO:0016053 ! organic acid biosynthetic process -is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:26650 ! serine family amino acid -relationship: has_primary_output CHEBI:26650 ! serine family amino acid +intersection_of: has_primary_output CHEBI:26650 +relationship: has_primary_output CHEBI:26650 [Term] id: GO:0009071 @@ -64008,12 +52629,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of amino ac synonym: "serine family amino acid breakdown" EXACT [] synonym: "serine family amino acid catabolism" EXACT [] synonym: "serine family amino acid degradation" EXACT [] +is_a: GO:0009056 ! catabolic process is_a: GO:0009069 ! serine family amino acid metabolic process -is_a: GO:0016054 ! organic acid catabolic process -is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:26650 ! serine family amino acid -relationship: has_primary_input CHEBI:26650 ! serine family amino acid +intersection_of: has_primary_input CHEBI:26650 +relationship: has_primary_input CHEBI:26650 [Term] id: GO:0009084 @@ -64024,12 +52644,11 @@ synonym: "glutamine family amino acid anabolism" EXACT [] synonym: "glutamine family amino acid biosynthesis" EXACT [] synonym: "glutamine family amino acid formation" EXACT [] synonym: "glutamine family amino acid synthesis" EXACT [] +is_a: GO:0009058 ! biosynthetic process is_a: GO:0009064 ! glutamine family amino acid metabolic process -is_a: GO:0016053 ! organic acid biosynthetic process -is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:24318 ! glutamine family amino acid -relationship: has_primary_output CHEBI:24318 ! glutamine family amino acid +intersection_of: has_primary_output CHEBI:24318 +relationship: has_primary_output CHEBI:24318 [Term] id: GO:0009100 @@ -64038,12 +52657,10 @@ namespace: biological_process def: "The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732] subset: goslim_drosophila synonym: "glycoprotein metabolism" EXACT [] -is_a: GO:0019538 ! protein metabolic process -is_a: GO:0044260 ! cellular macromolecule metabolic process -is_a: GO:1901135 ! carbohydrate derivative metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:17089 ! glycoprotein -relationship: has_primary_input_or_output CHEBI:17089 ! glycoprotein +intersection_of: has_primary_input_or_output CHEBI:17089 +relationship: has_primary_input_or_output CHEBI:17089 [Term] id: GO:0009101 @@ -64054,42 +52671,11 @@ synonym: "glycoprotein anabolism" EXACT [] synonym: "glycoprotein biosynthesis" EXACT [] synonym: "glycoprotein formation" EXACT [] synonym: "glycoprotein synthesis" EXACT [] +is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0009100 ! glycoprotein metabolic process -is_a: GO:0034645 ! cellular macromolecule biosynthetic process -is_a: GO:1901137 ! carbohydrate derivative biosynthetic process -is_a: GO:1901566 ! organonitrogen compound biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:17089 ! glycoprotein -relationship: has_primary_output CHEBI:17089 ! glycoprotein - -[Term] -id: GO:0009112 -name: nucleobase metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine." [GOC:ma] -synonym: "nucleobase metabolism" EXACT [] -is_a: GO:0055086 ! nucleobase-containing small molecule metabolic process -is_a: GO:1901564 ! organonitrogen compound metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:18282 ! nucleobase -relationship: has_primary_input_or_output CHEBI:18282 ! nucleobase - -[Term] -id: GO:0009247 -name: glycolipid biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide)." [GOC:go_curators] -synonym: "glycolipid anabolism" EXACT [] -synonym: "glycolipid biosynthesis" EXACT [] -synonym: "glycolipid formation" EXACT [] -synonym: "glycolipid synthesis" EXACT [] -xref: MetaCyc:PWY-401 -is_a: GO:0006664 ! glycolipid metabolic process -is_a: GO:0046467 ! membrane lipid biosynthetic process -is_a: GO:1901137 ! carbohydrate derivative biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:33563 ! glycolipid -relationship: has_primary_output CHEBI:33563 ! glycolipid +intersection_of: has_primary_output CHEBI:17089 +relationship: has_primary_output CHEBI:17089 [Term] id: GO:0009250 @@ -64100,11 +52686,11 @@ synonym: "glucan anabolism" EXACT [] synonym: "glucan biosynthesis" EXACT [] synonym: "glucan formation" EXACT [] synonym: "glucan synthesis" EXACT [] -is_a: GO:0006073 ! cellular glucan metabolic process -is_a: GO:0033692 ! cellular polysaccharide biosynthetic process +is_a: GO:0000271 ! polysaccharide biosynthetic process +is_a: GO:0044042 ! glucan metabolic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:37163 ! glucan -relationship: has_primary_output CHEBI:37163 ! glucan +intersection_of: has_primary_output CHEBI:37163 +relationship: has_primary_output CHEBI:37163 [Term] id: GO:0009251 @@ -64114,11 +52700,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of glucans, synonym: "glucan breakdown" EXACT [] synonym: "glucan catabolism" EXACT [] synonym: "glucan degradation" EXACT [] -is_a: GO:0000272 ! polysaccharide catabolic process +is_a: GO:0009056 ! catabolic process is_a: GO:0044042 ! glucan metabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:37163 ! glucan -relationship: has_primary_input CHEBI:37163 ! glucan +intersection_of: has_primary_input CHEBI:37163 +relationship: has_primary_input CHEBI:37163 [Term] id: GO:0009266 @@ -64154,10 +52740,10 @@ subset: goslim_chembl subset: goslim_pir synonym: "amine metabolism" EXACT [] synonym: "cellular amine metabolic process" EXACT [] -is_a: GO:1901564 ! organonitrogen compound metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:32952 ! amine -relationship: has_primary_input_or_output CHEBI:32952 ! amine +intersection_of: has_primary_input_or_output CHEBI:32952 +relationship: has_primary_input_or_output CHEBI:32952 created_by: jl creation_date: 2009-07-15T11:55:44Z @@ -64172,10 +52758,9 @@ synonym: "amine formation" EXACT [] synonym: "amine synthesis" EXACT [] is_a: GO:0009308 ! amine metabolic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process -is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:32952 ! amine -relationship: has_primary_output CHEBI:32952 ! amine +intersection_of: has_primary_output CHEBI:32952 +relationship: has_primary_output CHEBI:32952 [Term] id: GO:0009310 @@ -64185,11 +52770,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of any orga synonym: "amine breakdown" EXACT [] synonym: "amine catabolism" EXACT [] synonym: "amine degradation" EXACT [] +is_a: GO:0009056 ! catabolic process is_a: GO:0009308 ! amine metabolic process -is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:32952 ! amine -relationship: has_primary_input CHEBI:32952 ! amine +intersection_of: has_primary_input CHEBI:32952 +relationship: has_primary_input CHEBI:32952 [Term] id: GO:0009314 @@ -64244,8 +52829,8 @@ is_a: GO:0009628 ! response to abiotic stimulus is_a: GO:0010035 ! response to inorganic substance is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:15377 ! water -relationship: has_input CHEBI:15377 ! water +intersection_of: has_input CHEBI:15377 +relationship: has_input CHEBI:15377 [Term] id: GO:0009416 @@ -64255,8 +52840,8 @@ def: "Any process that results in a change in state or activity of a cell or an subset: goslim_plant is_a: GO:0009314 ! response to radiation intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:30212 ! photon -relationship: has_input CHEBI:30212 ! photon +intersection_of: has_input CHEBI:30212 +relationship: has_input CHEBI:30212 [Term] id: GO:0009448 @@ -64274,8 +52859,8 @@ synonym: "gamma-aminobutyric acid metabolism" EXACT [] is_a: GO:0006520 ! amino acid metabolic process is_a: GO:0032787 ! monocarboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:59888 ! gamma-aminobutyric acid zwitterion -relationship: has_primary_input_or_output CHEBI:59888 ! gamma-aminobutyric acid zwitterion +intersection_of: has_primary_input_or_output CHEBI:59888 +relationship: has_primary_input_or_output CHEBI:59888 [Term] id: GO:0009449 @@ -64293,11 +52878,11 @@ synonym: "gamma-aminobutyric acid anabolism" EXACT [] synonym: "gamma-aminobutyric acid biosynthesis" EXACT [] synonym: "gamma-aminobutyric acid formation" EXACT [] synonym: "gamma-aminobutyric acid synthesis" EXACT [] +is_a: GO:0009058 ! biosynthetic process is_a: GO:0009448 ! gamma-aminobutyric acid metabolic process -is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:59888 ! gamma-aminobutyric acid zwitterion -relationship: has_primary_output CHEBI:59888 ! gamma-aminobutyric acid zwitterion +intersection_of: has_primary_output CHEBI:59888 +relationship: has_primary_output CHEBI:59888 [Term] id: GO:0009450 @@ -64315,11 +52900,11 @@ synonym: "gamma-aminobutyric acid breakdown" EXACT [] synonym: "gamma-aminobutyric acid catabolism" EXACT [] synonym: "gamma-aminobutyric acid degradation" EXACT [] xref: MetaCyc:4AMINOBUTMETAB-PWY +is_a: GO:0009056 ! catabolic process is_a: GO:0009448 ! gamma-aminobutyric acid metabolic process -is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:59888 ! gamma-aminobutyric acid zwitterion -relationship: has_primary_input CHEBI:59888 ! gamma-aminobutyric acid zwitterion +intersection_of: has_primary_input CHEBI:59888 +relationship: has_primary_input CHEBI:59888 [Term] id: GO:0009566 @@ -64533,8 +53118,8 @@ synonym: "catechol metabolic process" RELATED [] synonym: "catechol metabolism" RELATED [] is_a: GO:0018958 ! phenol-containing compound metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:33566 ! catechols -relationship: has_primary_input_or_output CHEBI:33566 ! catechols +intersection_of: has_primary_input_or_output CHEBI:33566 +relationship: has_primary_input_or_output CHEBI:33566 [Term] id: GO:0009713 @@ -64546,11 +53131,11 @@ synonym: "catechol biosynthesis" RELATED [] synonym: "catechol biosynthetic process" RELATED [] synonym: "catechol formation" RELATED [] synonym: "catechol synthesis" RELATED [] +is_a: GO:0009058 ! biosynthetic process is_a: GO:0009712 ! catechol-containing compound metabolic process -is_a: GO:0046189 ! phenol-containing compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:33566 ! catechols -relationship: has_primary_output CHEBI:33566 ! catechols +intersection_of: has_primary_output CHEBI:33566 +relationship: has_primary_output CHEBI:33566 [Term] id: GO:0009719 @@ -64578,11 +53163,10 @@ name: response to carbohydrate namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus." [GOC:jl] synonym: "response to carbohydrate stimulus" EXACT [GOC:dos] -is_a: GO:0010033 ! response to organic substance -is_a: GO:1901700 ! response to oxygen-containing compound +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:16646 ! carbohydrate -relationship: has_input CHEBI:16646 ! carbohydrate +intersection_of: has_input CHEBI:16646 +relationship: has_input CHEBI:16646 [Term] id: GO:0009746 @@ -64590,10 +53174,10 @@ name: response to hexose namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus." [GOC:jl] synonym: "response to hexose stimulus" EXACT [GOC:dos] -is_a: GO:0034284 ! response to monosaccharide +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:18133 ! hexose -relationship: has_input CHEBI:18133 ! hexose +intersection_of: has_input CHEBI:18133 +relationship: has_input CHEBI:18133 [Term] id: GO:0009749 @@ -64601,10 +53185,10 @@ name: response to glucose namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus." [GOC:jl] synonym: "response to glucose stimulus" EXACT [GOC:dos] -is_a: GO:0009746 ! response to hexose +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:17234 ! glucose -relationship: has_input CHEBI:17234 ! glucose +intersection_of: has_input CHEBI:17234 +relationship: has_input CHEBI:17234 [Term] id: GO:0009755 @@ -64670,50 +53254,6 @@ def: "The establishment, maintenance and elaboration of a pattern along a line o synonym: "axis determination" RELATED [] is_a: GO:0007389 ! pattern specification process -[Term] -id: GO:0009820 -name: alkaloid metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743] -subset: goslim_chembl -synonym: "alkaloid metabolism" EXACT [] -is_a: GO:1901564 ! organonitrogen compound metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:22315 ! alkaloid -relationship: has_primary_input_or_output CHEBI:22315 ! alkaloid - -[Term] -id: GO:0009821 -name: alkaloid biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743] -synonym: "alkaloid anabolism" EXACT [] -synonym: "alkaloid biosynthesis" EXACT [] -synonym: "alkaloid formation" EXACT [] -synonym: "alkaloid synthesis" EXACT [] -xref: UM-BBD_enzymeID:e0711 -is_a: GO:0009820 ! alkaloid metabolic process -is_a: GO:0044550 ! secondary metabolite biosynthetic process -is_a: GO:1901566 ! organonitrogen compound biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:22315 ! alkaloid -relationship: has_primary_output CHEBI:22315 ! alkaloid - -[Term] -id: GO:0009822 -name: alkaloid catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743] -synonym: "alkaloid breakdown" EXACT [] -synonym: "alkaloid catabolism" EXACT [] -synonym: "alkaloid degradation" EXACT [] -is_a: GO:0009820 ! alkaloid metabolic process -is_a: GO:0044270 ! cellular nitrogen compound catabolic process -is_a: GO:1901565 ! organonitrogen compound catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:22315 ! alkaloid -relationship: has_primary_input CHEBI:22315 ! alkaloid - [Term] id: GO:0009880 name: embryonic pattern specification @@ -65014,6 +53554,7 @@ alt_id: GO:0008151 alt_id: GO:0044763 alt_id: GO:0050875 def: "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators, GOC:isa_complete] +comment: This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term. subset: gocheck_do_not_annotate subset: goslim_plant synonym: "cell growth and/or maintenance" NARROW [] @@ -65032,10 +53573,9 @@ def: "A homeostatic process involved in the maintenance of a steady state level synonym: "cellular osmoregulation" RELATED [GOC:dph, GOC:tb] synonym: "cellular water homeostasis" EXACT [] is_a: GO:0006884 ! cell volume homeostasis -is_a: GO:0030104 ! water homeostasis -is_a: GO:0055082 ! intracellular chemical homeostasis intersection_of: GO:0019725 ! cellular homeostasis -intersection_of: regulates_levels_of CHEBI:15377 ! water +intersection_of: regulates_levels_of CHEBI:15377 +relationship: regulates_levels_of CHEBI:15377 [Term] id: GO:0009994 @@ -65109,19 +53649,8 @@ def: "Any process that results in a change in state or activity of a cell or an synonym: "process resulting in tolerance to organic substance" NARROW [] is_a: GO:0042221 ! response to chemical intersection_of: GO:0042221 ! response to chemical -intersection_of: has_input CHEBI:50860 ! organic molecular entity -relationship: has_input CHEBI:50860 ! organic molecular entity - -[Term] -id: GO:0010034 -name: response to acetate -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus." [GOC:sm] -is_a: GO:0010033 ! response to organic substance -is_a: GO:1901700 ! response to oxygen-containing compound -intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:30089 ! acetate -relationship: has_input CHEBI:30089 ! acetate +intersection_of: has_input CHEBI:50860 +relationship: has_input CHEBI:50860 [Term] id: GO:0010035 @@ -65130,21 +53659,8 @@ namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus." [GOC:sm] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:24835 ! inorganic molecular entity -relationship: has_input CHEBI:24835 ! inorganic molecular entity - -[Term] -id: GO:0010038 -name: response to metal ion -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus." [GOC:sm] -synonym: "heavy metal sensitivity/resistance" RELATED [] -synonym: "response to heavy metal" NARROW [] -synonym: "response to metal" EXACT [] -is_a: GO:0010035 ! response to inorganic substance -intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:25213 ! metal cation -relationship: has_input CHEBI:25213 ! metal cation +intersection_of: has_input CHEBI:24835 +relationship: has_input CHEBI:24835 [Term] id: GO:0010039 @@ -65152,10 +53668,10 @@ name: response to iron ion namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus." [GOC:sm] synonym: "response to iron" EXACT [] -is_a: GO:0010038 ! response to metal ion +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:24875 ! iron cation -relationship: has_input CHEBI:24875 ! iron cation +intersection_of: has_input CHEBI:24875 +relationship: has_input CHEBI:24875 [Term] id: GO:0010070 @@ -65216,11 +53732,10 @@ name: response to organonitrogen compound namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond." [PMID:9869419] synonym: "response to organic nitrogen" EXACT [] -is_a: GO:0010033 ! response to organic substance -is_a: GO:1901698 ! response to nitrogen compound +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:35352 ! organonitrogen compound -relationship: has_input CHEBI:35352 ! organonitrogen compound +intersection_of: has_input CHEBI:35352 +relationship: has_input CHEBI:35352 [Term] id: GO:0010256 @@ -65518,8 +54033,8 @@ id: GO:0010559 name: regulation of glycoprotein biosynthetic process namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] +is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:1903018 ! regulation of glycoprotein metabolic process -is_a: GO:2000112 ! regulation of cellular macromolecule biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009101 ! glycoprotein biosynthetic process relationship: regulates GO:0009101 ! glycoprotein biosynthetic process @@ -65531,7 +54046,6 @@ namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process -is_a: GO:0031328 ! positive regulation of cellular biosynthetic process is_a: GO:1903020 ! positive regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009101 ! glycoprotein biosynthetic process @@ -65542,35 +54056,13 @@ id: GO:0010561 name: negative regulation of glycoprotein biosynthetic process namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] +is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process is_a: GO:1903019 ! negative regulation of glycoprotein metabolic process -is_a: GO:2000113 ! negative regulation of cellular macromolecule biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009101 ! glycoprotein biosynthetic process relationship: negatively_regulates GO:0009101 ! glycoprotein biosynthetic process -[Term] -id: GO:0010562 -name: positive regulation of phosphorus metabolic process -namespace: biological_process -def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb] -is_a: GO:0031325 ! positive regulation of cellular metabolic process -is_a: GO:0051174 ! regulation of phosphorus metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0006793 ! phosphorus metabolic process -relationship: positively_regulates GO:0006793 ! phosphorus metabolic process - -[Term] -id: GO:0010563 -name: negative regulation of phosphorus metabolic process -namespace: biological_process -def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb] -is_a: GO:0031324 ! negative regulation of cellular metabolic process -is_a: GO:0051174 ! regulation of phosphorus metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0006793 ! phosphorus metabolic process -relationship: negatively_regulates GO:0006793 ! phosphorus metabolic process - [Term] id: GO:0010564 name: regulation of cell cycle process @@ -66086,41 +54578,6 @@ intersection_of: results_in_acquisition_of_features_of CL:0000221 ! ectodermal c relationship: part_of GO:0007398 ! ectoderm development relationship: results_in_acquisition_of_features_of CL:0000221 ! ectodermal cell -[Term] -id: GO:0010675 -name: regulation of cellular carbohydrate metabolic process -namespace: biological_process -def: "Any process that modulates the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells." [GOC:dph, GOC:tb] -is_a: GO:0006109 ! regulation of carbohydrate metabolic process -is_a: GO:0031323 ! regulation of cellular metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0044262 ! cellular carbohydrate metabolic process -relationship: regulates GO:0044262 ! cellular carbohydrate metabolic process - -[Term] -id: GO:0010676 -name: positive regulation of cellular carbohydrate metabolic process -namespace: biological_process -def: "Any process that increases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells." [GOC:dph, GOC:tb] -is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process -is_a: GO:0031325 ! positive regulation of cellular metabolic process -is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0044262 ! cellular carbohydrate metabolic process -relationship: positively_regulates GO:0044262 ! cellular carbohydrate metabolic process - -[Term] -id: GO:0010677 -name: negative regulation of cellular carbohydrate metabolic process -namespace: biological_process -def: "Any process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells." [GOC:dph, GOC:tb] -is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process -is_a: GO:0031324 ! negative regulation of cellular metabolic process -is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0044262 ! cellular carbohydrate metabolic process -relationship: negatively_regulates GO:0044262 ! cellular carbohydrate metabolic process - [Term] id: GO:0010700 name: negative regulation of norepinephrine secretion @@ -66433,28 +54890,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010761 ! fibroblast migration relationship: negatively_regulates GO:0010761 ! fibroblast migration -[Term] -id: GO:0010765 -name: positive regulation of sodium ion transport -namespace: biological_process -def: "Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] -is_a: GO:0002028 ! regulation of sodium ion transport -is_a: GO:0043270 ! positive regulation of monoatomic ion transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0006814 ! sodium ion transport -relationship: positively_regulates GO:0006814 ! sodium ion transport - -[Term] -id: GO:0010766 -name: negative regulation of sodium ion transport -namespace: biological_process -def: "Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] -is_a: GO:0002028 ! regulation of sodium ion transport -is_a: GO:0043271 ! negative regulation of monoatomic ion transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0006814 ! sodium ion transport -relationship: negatively_regulates GO:0006814 ! sodium ion transport - [Term] id: GO:0010769 name: regulation of cell morphogenesis involved in differentiation @@ -66493,10 +54928,9 @@ name: calcitonin catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin." [GOC:BHF, GOC:rl] is_a: GO:0042447 ! hormone catabolic process -is_a: GO:0043171 ! peptide catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:3306 ! calcitonin -relationship: has_primary_input CHEBI:3306 ! calcitonin +intersection_of: has_primary_input CHEBI:3306 +relationship: has_primary_input CHEBI:3306 [Term] id: GO:0010817 @@ -66659,8 +55093,8 @@ def: "Any process in which a lipid is transported to, or maintained in, a specif synonym: "lipid localisation" EXACT [GOC:mah] is_a: GO:0033036 ! macromolecule localization intersection_of: GO:0033036 ! macromolecule localization -intersection_of: has_primary_input CHEBI:18059 ! lipid -relationship: has_primary_input CHEBI:18059 ! lipid +intersection_of: has_primary_input CHEBI:18059 +relationship: has_primary_input CHEBI:18059 [Term] id: GO:0010882 @@ -66703,8 +55137,7 @@ name: regulation of glucose metabolic process namespace: biological_process def: "Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose." [GOC:BHF, GOC:tb] synonym: "regulation of glucose metabolism" EXACT [GOC:tb] -is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process -is_a: GO:0062012 ! regulation of small molecule metabolic process +is_a: GO:0006109 ! regulation of carbohydrate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006006 ! glucose metabolic process relationship: regulates GO:0006006 ! glucose metabolic process @@ -66715,9 +55148,8 @@ name: positive regulation of glucose metabolic process namespace: biological_process def: "Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose." [GOC:BHF, GOC:tb] synonym: "positive regulation of glucose metabolism" EXACT [GOC:tb] -is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process is_a: GO:0010906 ! regulation of glucose metabolic process -is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006006 ! glucose metabolic process relationship: positively_regulates GO:0006006 ! glucose metabolic process @@ -66896,44 +55328,18 @@ relationship: negatively_regulates GO:0016485 ! protein processing created_by: tb creation_date: 2009-04-27T12:10:19Z -[Term] -id: GO:0010959 -name: regulation of metal ion transport -namespace: biological_process -def: "Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] -is_a: GO:0043269 ! regulation of monoatomic ion transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0030001 ! metal ion transport -relationship: regulates GO:0030001 ! metal ion transport -created_by: tb -creation_date: 2009-05-06T11:40:55Z - [Term] id: GO:0010962 name: regulation of glucan biosynthetic process namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues." [GOC:dph, GOC:tb] -is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process -is_a: GO:2000112 ! regulation of cellular macromolecule biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009250 ! glucan biosynthetic process relationship: regulates GO:0009250 ! glucan biosynthetic process created_by: tb creation_date: 2009-05-11T12:17:53Z -[Term] -id: GO:0010966 -name: regulation of phosphate transport -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] -is_a: GO:0051049 ! regulation of transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0006817 ! phosphate ion transport -relationship: regulates GO:0006817 ! phosphate ion transport -created_by: tb -creation_date: 2009-05-20T11:42:50Z - [Term] id: GO:0010968 name: regulation of microtubule nucleation @@ -67021,7 +55427,12 @@ namespace: biological_process alt_id: GO:0016244 def: "A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell." [GOC:lr, GOC:mtg_apoptosis] comment: Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children. +subset: goslim_agr +subset: goslim_chembl +subset: goslim_drosophila subset: goslim_generic +subset: goslim_mouse +subset: goslim_plant subset: prokaryote_subset synonym: "caspase-independent apoptosis" RELATED [] synonym: "caspase-independent cell death" NARROW [] @@ -67035,6 +55446,7 @@ is_a: GO:0008219 ! cell death intersection_of: GO:0008219 ! cell death intersection_of: starts_with GO:0007165 ! signal transduction relationship: starts_with GO:0007165 ! signal transduction +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24835" xsd:anyURI [Term] id: GO:0012505 @@ -67449,7 +55861,7 @@ def: "The regulated release of dopamine by a cell. Dopamine is a catecholamine a is_a: GO:0015872 ! dopamine transport is_a: GO:0023061 ! signal release intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:59905 ! dopaminium(1+) +intersection_of: has_primary_input CHEBI:59905 [Term] id: GO:0014047 @@ -67458,10 +55870,9 @@ namespace: biological_process def: "The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system." [GOC:ef] is_a: GO:0015800 ! acidic amino acid transport is_a: GO:0032940 ! secretion by cell -is_a: GO:0046942 ! carboxylic acid transport intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:14321 ! glutamate(1-) -relationship: has_primary_input CHEBI:14321 ! glutamate(1-) +intersection_of: has_primary_input CHEBI:14321 +relationship: has_primary_input CHEBI:14321 [Term] id: GO:0014048 @@ -67516,7 +55927,7 @@ synonym: "GABA secretion" EXACT [] is_a: GO:0015812 ! gamma-aminobutyric acid transport is_a: GO:0046717 ! acid secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:59888 ! gamma-aminobutyric acid zwitterion +intersection_of: has_primary_input CHEBI:59888 [Term] id: GO:0014052 @@ -67636,7 +56047,7 @@ name: regulation of epinephrine secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of epinephrine." [GOC:ef] synonym: "regulation of adrenaline secretion" EXACT [] -is_a: GO:0050433 ! regulation of catecholamine secretion +is_a: GO:0051046 ! regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048242 ! epinephrine secretion relationship: regulates GO:0048242 ! epinephrine secretion @@ -67705,10 +56116,10 @@ name: response to organic cyclic compound namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus." [GOC:ef] synonym: "response to organic cyclic substance" EXACT [GOC:mah] -is_a: GO:0010033 ! response to organic substance +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:33832 ! organic cyclic compound -relationship: has_input CHEBI:33832 ! organic cyclic compound +intersection_of: has_input CHEBI:33832 +relationship: has_input CHEBI:33832 [Term] id: GO:0014075 @@ -67716,10 +56127,10 @@ name: response to amine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." [GOC:ef] synonym: "response to amine stimulus" EXACT [GOC:dos] -is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:32952 ! amine -relationship: has_input CHEBI:32952 ! amine +intersection_of: has_input CHEBI:32952 +relationship: has_input CHEBI:32952 [Term] id: GO:0014706 @@ -68380,7 +56791,6 @@ subset: goslim_yeast synonym: "enzyme transport" NARROW [] is_a: GO:0045184 ! establishment of protein localization is_a: GO:0071702 ! organic substance transport -is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input PR:000000001 ! protein @@ -68393,26 +56803,11 @@ synonym: "ion transmembrane transporter activity" BROAD [] synonym: "ion transporter activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion -relationship: has_primary_input CHEBI:24867 ! monoatomic ion +intersection_of: has_primary_input CHEBI:24867 +relationship: has_primary_input CHEBI:24867 relationship: part_of GO:0034220 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! monoatomic ion transmembrane transport property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI -[Term] -id: GO:0015081 -name: sodium ion transmembrane transporter activity -namespace: molecular_function -alt_id: GO:0022816 -def: "Enables the transfer of sodium ions (Na+) from one side of a membrane to the other." [GOC:ai, GOC:BHF, RHEA:34963] -synonym: "sodium transporter activity" EXACT [] -xref: RHEA:34963 -is_a: GO:0046873 ! metal ion transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:29101 ! sodium(1+) -relationship: has_primary_input CHEBI:29101 ! sodium(1+) -relationship: part_of GO:0035725 ! sodium ion transmembrane transport -property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24076" xsd:anyURI - [Term] id: GO:0015085 name: calcium ion transmembrane transporter activity @@ -68420,40 +56815,11 @@ namespace: molecular_function def: "Enables the transfer of calcium (Ca) ions from one side of a membrane to the other." [GOC:dgf, RHEA:29671] xref: Reactome:R-HSA-2534359 "CatSper Channel Mediated Calcium Transport" xref: RHEA:29671 -is_a: GO:0046873 ! metal ion transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:29108 ! calcium(2+) -relationship: has_primary_input CHEBI:29108 ! calcium(2+) -relationship: part_of GO:0070588 ! calcium ion transmembrane transport - -[Term] -id: GO:0015101 -name: organic cation transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] -xref: Reactome:R-HSA-2161500 "abacavir [extracellular] => abacavir [cytosol]" -xref: Reactome:R-HSA-549129 "OCT1 transports organic cations into hepatic cells" -xref: Reactome:R-HSA-549279 "OCT2 mediates tubular uptake of organic cations in the kidney" -xref: Reactome:R-HSA-549304 "OCT3 mediates renal clearance of organic cations" -xref: Reactome:R-HSA-549322 "OCT1 transports organic cations out of hepatic cells" -xref: Reactome:R-HSA-561054 "OCT2 mediates tubular secretion of organic cations in the kidney" -xref: Reactome:R-HSA-561072 "OCT3 mediates renal uptake of organic cations" is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:25697 ! organic cation -relationship: has_primary_input CHEBI:25697 ! organic cation -relationship: part_of GO:0015695 ! organic cation transport - -[Term] -id: GO:0015103 -name: inorganic anion transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." [GOC:ai] -is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:24834 ! inorganic anion -relationship: has_primary_input CHEBI:24834 ! inorganic anion -relationship: part_of GO:0015698 ! inorganic anion transport +intersection_of: has_primary_input CHEBI:29108 +relationship: has_primary_input CHEBI:29108 +relationship: part_of GO:0070588 ! calcium ion transmembrane transport [Term] id: GO:0015106 @@ -68462,57 +56828,12 @@ namespace: molecular_function def: "Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-." [GOC:ai] xref: Reactome:R-HSA-2752067 "BESTs transport cytosolic HCO3- to extracellular region" xref: RHEA:28695 -is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:17544 ! hydrogencarbonate -relationship: has_primary_input CHEBI:17544 ! hydrogencarbonate +intersection_of: has_primary_input CHEBI:17544 +relationship: has_primary_input CHEBI:17544 relationship: part_of GO:0015701 ! bicarbonate transport -[Term] -id: GO:0015114 -name: phosphate ion transmembrane transporter activity -namespace: molecular_function -alt_id: GO:1901677 -def: "Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other." [GOC:ai] -synonym: "phosphate transmembrane transporter activity" RELATED [GOC:vw] -xref: RHEA:32823 -is_a: GO:0015103 ! inorganic anion transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:35780 ! phosphate ion -relationship: has_primary_input CHEBI:35780 ! phosphate ion -relationship: part_of GO:0035435 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! phosphate ion transmembrane transport -created_by: pr -creation_date: 2012-11-22T15:43:10Z - -[Term] -id: GO:0015116 -name: sulfate transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other." [GOC:ai] -synonym: "sulfate permease activity" RELATED [] -synonym: "sulphate transporter activity" EXACT [] -xref: Reactome:R-HSA-3560789 "Defective SLC26A2 does not cotransport extracellular SO4(2-), H+ to cytosol" -xref: Reactome:R-HSA-427555 "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol" -xref: Reactome:R-HSA-8875871 "SLC26A11 transports SO4(2-) from extracellular region to cytosol" -xref: RHEA:34983 -is_a: GO:0015103 ! inorganic anion transmembrane transporter activity -is_a: GO:1901682 ! sulfur compound transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:16189 ! sulfate -relationship: has_primary_input CHEBI:16189 ! sulfate -relationship: part_of GO:1902358 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! sulfate transmembrane transport - -[Term] -id: GO:0015123 -name: acetate transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid." [GOC:ai] -is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:30089 ! acetate -relationship: has_primary_input CHEBI:30089 ! acetate -relationship: part_of GO:0035433 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! acetate transmembrane transport - [Term] id: GO:0015125 name: bile acid transmembrane transporter activity @@ -68523,28 +56844,12 @@ xref: Reactome:R-HSA-194083 "SLCO1B1 transports ALB:(GCCA,TCCA) from extracellul xref: Reactome:R-HSA-194130 "Transport (influx) of bile salts and acids by OATP-A" xref: Reactome:R-HSA-5661184 "Defective SLCO1B1 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte)" xref: Reactome:R-HSA-5661198 "Defective SLCO1B3 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte)" -is_a: GO:0005319 ! lipid transporter activity -is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity -is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity +is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:3098 ! bile acid -relationship: has_primary_input CHEBI:3098 ! bile acid +intersection_of: has_primary_input CHEBI:3098 +relationship: has_primary_input CHEBI:3098 relationship: part_of GO:0015721 ! bile acid and bile salt transport -[Term] -id: GO:0015127 -name: bilirubin transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile." [GOC:ai, ISBN:0198547684] -xref: Reactome:R-HSA-5679031 "Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region" -xref: Reactome:R-HSA-5679041 "ABCC2 transports BMG,BDG from cytosol to extracellular region" -xref: Reactome:R-HSA-9661417 "ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region" -is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:57977 ! bilirubin(2-) -relationship: has_primary_input CHEBI:57977 ! bilirubin(2-) -relationship: part_of GO:0015723 ! bilirubin transport - [Term] id: GO:0015144 name: carbohydrate transmembrane transporter activity @@ -68555,21 +56860,10 @@ synonym: "carbohydrate transporter activity" RELATED [] synonym: "sugar transporter" NARROW [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:16646 ! carbohydrate -relationship: has_primary_input CHEBI:16646 ! carbohydrate +intersection_of: has_primary_input CHEBI:16646 +relationship: has_primary_input CHEBI:16646 relationship: part_of GO:0034219 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! carbohydrate transmembrane transport -[Term] -id: GO:0015145 -name: monosaccharide transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of a monosaccharide from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] -is_a: GO:0051119 ! sugar transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:35381 ! monosaccharide -relationship: has_primary_input CHEBI:35381 ! monosaccharide -relationship: part_of GO:0015749 ! monosaccharide transmembrane transport - [Term] id: GO:0015149 name: hexose transmembrane transporter activity @@ -68577,10 +56871,10 @@ namespace: molecular_function def: "Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: Reactome:R-HSA-189242 "SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region" xref: Reactome:R-HSA-5638222 "Defective SLC2A2 does not transport Fru, Gal, Glc from cytosol to extracellular region" -is_a: GO:0015145 ! monosaccharide transmembrane transporter activity +is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:18133 ! hexose -relationship: has_primary_input CHEBI:18133 ! hexose +intersection_of: has_primary_input CHEBI:18133 +relationship: has_primary_input CHEBI:18133 relationship: part_of GO:0008645 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! hexose transmembrane transport [Term] @@ -68588,11 +56882,10 @@ id: GO:0015159 name: polysaccharide transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] -is_a: GO:0015144 ! carbohydrate transmembrane transporter activity -is_a: GO:0022884 ! macromolecule transmembrane transporter activity +is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:18154 ! polysaccharide -relationship: has_primary_input CHEBI:18154 ! polysaccharide +intersection_of: has_primary_input CHEBI:18154 +relationship: has_primary_input CHEBI:18154 relationship: part_of GO:0015774 ! polysaccharide transport [Term] @@ -68652,12 +56945,37 @@ xref: Reactome:R-HSA-5660890 "Defective SLC7A9 (in SLC7A9:SLC3A1) does not excha xref: Reactome:R-HSA-5660910 "Defective SLC7A7 does not exchange L-Arg for L-Leu, Na+ across the plasma membrane" xref: Reactome:R-HSA-888592 "Loading of GABA into clathrin sculpted GABA transport vesicle lumen" xref: Reactome:R-HSA-8952726 "SLC38A9 transports L-Arg from lysosomal lumen to cytosol" -is_a: GO:0005342 ! organic acid transmembrane transporter activity +is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:33709 ! amino acid -relationship: has_primary_input CHEBI:33709 ! amino acid +intersection_of: has_primary_input CHEBI:33709 +relationship: has_primary_input CHEBI:33709 relationship: part_of GO:0003333 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! amino acid transmembrane transport +[Term] +id: GO:0015172 +name: acidic amino acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "acidic amino acid transporter activity" BROAD [] +xref: Reactome:R-HSA-372448 "SLC25A12,13 exchange cytosolic L-Glu for mitochondrial matrix L-Asp" +is_a: GO:0015171 ! amino acid transmembrane transporter activity +relationship: part_of GO:0015800 ! acidic amino acid transport + +[Term] +id: GO:0015174 +name: basic amino acid transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005286 +alt_id: GO:0015326 +def: "Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have side chains with a positive charge at pH 7.3." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "basic amino acid permease activity" EXACT [] +synonym: "basic amino acid transporter activity" BROAD [] +synonym: "cationic amino acid transmembrane transporter activity" RELATED [] +xref: Reactome:R-HSA-8932851 "PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol" +xref: Reactome:R-HSA-8959781 "SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix" +is_a: GO:0015171 ! amino acid transmembrane transporter activity +relationship: part_of GO:1990822 ! basic amino acid transmembrane transport + [Term] id: GO:0015175 name: neutral L-amino acid transmembrane transporter activity @@ -68668,19 +56986,6 @@ synonym: "neutral amino acid transporter activity" BROAD [] is_a: GO:0015171 ! amino acid transmembrane transporter activity relationship: part_of GO:0015804 ! neutral amino acid transport -[Term] -id: GO:0015179 -name: L-amino acid transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids." [GOC:ai, GOC:jsg, GOC:mah, GOC:mtg_transport, ISBN:0815340729] -synonym: "L-amino acid transporter activity" BROAD [] -xref: Reactome:R-HSA-212614 "Glutamine transport from astrocytes" -is_a: GO:0022857 ! transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:59869 ! L-alpha-amino acid zwitterion -relationship: has_primary_input CHEBI:59869 ! L-alpha-amino acid zwitterion -relationship: part_of GO:1902475 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! L-alpha-amino acid transmembrane transport - [Term] id: GO:0015185 name: gamma-aminobutyric acid transmembrane transporter activity @@ -68692,8 +56997,8 @@ synonym: "betaine/GABA:sodium symporter activity" NARROW [] synonym: "GABA transporter activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:59888 ! gamma-aminobutyric acid zwitterion -relationship: has_primary_input CHEBI:59888 ! gamma-aminobutyric acid zwitterion +intersection_of: has_primary_input CHEBI:59888 +relationship: has_primary_input CHEBI:59888 relationship: part_of GO:0015812 ! gamma-aminobutyric acid transport [Term] @@ -68706,42 +57011,10 @@ synonym: "glycine transporter activity" BROAD [] synonym: "proline/glycine/betaine:hydrogen/sodium symporter activity" NARROW [] is_a: GO:0015175 ! neutral L-amino acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:57305 ! glycine zwitterion -relationship: has_primary_input CHEBI:57305 ! glycine zwitterion +intersection_of: has_primary_input CHEBI:57305 +relationship: has_primary_input CHEBI:57305 relationship: part_of GO:0015816 ! glycine transport -[Term] -id: GO:0015205 -name: nucleobase transmembrane transporter activity -namespace: molecular_function -alt_id: GO:0015392 -def: "Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other." [ISBN:0198506732] -is_a: GO:0022857 ! transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:18282 ! nucleobase -relationship: has_primary_input CHEBI:18282 ! nucleobase -relationship: part_of GO:0015851 ! nucleobase transport - -[Term] -id: GO:0015245 -name: fatty acid transmembrane transporter activity -namespace: molecular_function -alt_id: GO:0015246 -def: "Enables the transfer of fatty acids from one side of a membrane to the other. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis." [ISBN:0198506732] -synonym: "fatty acid transporter activity" RELATED [] -synonym: "fatty acyl transporter activity" EXACT [] -synonym: "fatty-acyl group transporter activity" BROAD [] -synonym: "peroxisomal fatty acyl transporter" NARROW [] -xref: Reactome:R-HSA-5627891 "Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol" -xref: Reactome:R-HSA-879585 "SLC27A1,4,6 transport LCFAs from extracellular region to cytosol" -is_a: GO:0005319 ! lipid transporter activity -is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity -intersection_of: GO:0005215 ! transporter activity -intersection_of: has_primary_input CHEBI:28868 ! fatty acid anion -intersection_of: results_in_transport_across GO:0016020 ! membrane -relationship: has_primary_input CHEBI:28868 ! fatty acid anion -relationship: part_of GO:0015908 ! fatty acid transport - [Term] id: GO:0015250 name: water channel activity @@ -68759,7 +57032,7 @@ xref: RHEA:29667 is_a: GO:0005372 ! water transmembrane transporter activity is_a: GO:0015267 ! channel activity intersection_of: GO:0015267 ! channel activity -intersection_of: has_primary_input CHEBI:15377 ! water +intersection_of: has_primary_input CHEBI:15377 [Term] id: GO:0015267 @@ -68796,7 +57069,7 @@ xref: Reactome:R-HSA-629595 "Activation of highly calcium permeable postsynaptic is_a: GO:0022834 ! ligand-gated channel activity is_a: GO:0022839 ! monoatomic ion gated channel activity intersection_of: GO:0022834 ! ligand-gated channel activity -intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion +intersection_of: has_primary_input CHEBI:24867 [Term] id: GO:0015318 @@ -68808,8 +57081,8 @@ synonym: "inorganic solute uptake transmembrane transporter activity" EXACT [] synonym: "inorganic uptake permease activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:24835 ! inorganic molecular entity -relationship: has_primary_input CHEBI:24835 ! inorganic molecular entity +intersection_of: has_primary_input CHEBI:24835 +relationship: has_primary_input CHEBI:24835 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14372" xsd:anyURI [Term] @@ -68821,37 +57094,11 @@ comment: For nicotinic acetylcholine receptors that act as ion channels, instead is_a: GO:0004888 ! transmembrane signaling receptor activity is_a: GO:0098960 ! postsynaptic neurotransmitter receptor activity intersection_of: GO:0038023 ! signaling receptor activity -intersection_of: has_input CHEBI:15355 ! acetylcholine -relationship: has_input CHEBI:15355 ! acetylcholine +intersection_of: has_input CHEBI:15355 +relationship: has_input CHEBI:15355 relationship: has_part GO:0042166 ! acetylcholine binding relationship: part_of GO:0007271 ! synaptic transmission, cholinergic -[Term] -id: GO:0015499 -name: formate transmembrane transporter activity -namespace: molecular_function -alt_id: GO:0015659 -def: "Enables the transfer of formate from one side of a membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid." [GOC:ai] -synonym: "formate uptake permease activity" EXACT [] -synonym: "formate uptake transmembrane transporter activity" RELATED [] -xref: RHEA:29679 -is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:15740 ! formate -relationship: has_primary_input CHEBI:15740 ! formate -relationship: part_of GO:0015724 ! formate transport - -[Term] -id: GO:0015567 -name: alkane transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of alkanes from one side of a membrane to the other. Alkanes are saturated aliphatic hydrocarbon compounds." [GOC:ai] -is_a: GO:0022857 ! transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:18310 ! alkane -relationship: has_primary_input CHEBI:18310 ! alkane -relationship: part_of GO:0015895 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! alkane transport - [Term] id: GO:0015629 name: actin cytoskeleton @@ -68873,31 +57120,6 @@ namespace: molecular_function def: "Binding to monomeric or multimeric forms of tubulin, including microtubules." [GOC:clt] is_a: GO:0008092 ! cytoskeletal protein binding -[Term] -id: GO:0015636 -name: short-chain fatty acid transmembrane transporter activity -namespace: molecular_function -alt_id: GO:0015635 -def: "Enables the transfer of short-chain fatty acids from one side of a membrane to the other. Short-chain fatty acids are fatty acids with a chain length of less than C6." [GOC:mah] -synonym: "short-chain fatty acid transporter activity" RELATED [] -synonym: "short-chain fatty acid uptake transporter activity" RELATED [] -is_a: GO:0015245 ! fatty acid transmembrane transporter activity -intersection_of: GO:0005215 ! transporter activity -intersection_of: has_primary_input CHEBI:58951 ! short-chain fatty acid anion -intersection_of: results_in_transport_across GO:0016020 ! membrane -relationship: has_primary_input CHEBI:58951 ! short-chain fatty acid anion -relationship: part_of GO:0015912 ! short-chain fatty acid transport - -[Term] -id: GO:0015665 -name: alcohol transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of an alcohol from one side of a membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group." [ISBN:0198506732] -is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:30879 ! alcohol -relationship: has_primary_input CHEBI:30879 ! alcohol - [Term] id: GO:0015669 name: gas transport @@ -68913,48 +57135,18 @@ namespace: biological_process def: "The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0015669 ! gas transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:15379 ! dioxygen -relationship: has_primary_input CHEBI:15379 ! dioxygen - -[Term] -id: GO:0015695 -name: organic cation transport -namespace: biological_process -def: "The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage." [GOC:ai] -is_a: GO:0071702 ! organic substance transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:25697 ! organic cation -relationship: has_primary_input CHEBI:25697 ! organic cation - -[Term] -id: GO:0015698 -name: inorganic anion transport -namespace: biological_process -def: "The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." [GOC:krc] -is_a: GO:0006810 ! transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:24834 ! inorganic anion -relationship: has_primary_input CHEBI:24834 ! inorganic anion +intersection_of: has_primary_input CHEBI:15379 +relationship: has_primary_input CHEBI:15379 [Term] id: GO:0015701 name: bicarbonate transport namespace: biological_process def: "The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] -is_a: GO:0015711 ! organic anion transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:17544 ! hydrogencarbonate -relationship: has_primary_input CHEBI:17544 ! hydrogencarbonate - -[Term] -id: GO:0015711 -name: organic anion transport -namespace: biological_process -def: "The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." [GOC:ai, GOC:krc] -is_a: GO:0071702 ! organic substance transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:25696 ! organic anion -relationship: has_primary_input CHEBI:25696 ! organic anion +intersection_of: has_primary_input CHEBI:17544 +relationship: has_primary_input CHEBI:17544 [Term] id: GO:0015718 @@ -68963,8 +57155,8 @@ namespace: biological_process def: "The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0046942 ! carboxylic acid transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:35757 ! monocarboxylic acid anion -relationship: has_primary_input CHEBI:35757 ! monocarboxylic acid anion +intersection_of: has_primary_input CHEBI:35757 +relationship: has_primary_input CHEBI:35757 [Term] id: GO:0015721 @@ -68975,56 +57167,20 @@ synonym: "bile acid transport" NARROW [] synonym: "bile salt transport" NARROW [] is_a: GO:0006869 ! lipid transport is_a: GO:0015718 ! monocarboxylic acid transport -is_a: GO:0015849 ! organic acid transport is_a: GO:0015850 ! organic hydroxy compound transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:3098 ! bile acid -relationship: has_primary_input CHEBI:3098 ! bile acid - -[Term] -id: GO:0015723 -name: bilirubin transport -namespace: biological_process -def: "The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] -is_a: GO:0006835 ! dicarboxylic acid transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:57977 ! bilirubin(2-) -relationship: has_primary_input CHEBI:57977 ! bilirubin(2-) - -[Term] -id: GO:0015724 -name: formate transport -namespace: biological_process -def: "The directed movement of formate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] -is_a: GO:0015718 ! monocarboxylic acid transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:15740 ! formate -relationship: has_primary_input CHEBI:15740 ! formate - -[Term] -id: GO:0015749 -name: monosaccharide transmembrane transport -namespace: biological_process -alt_id: GO:1905950 -def: "The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." [GO_REF:0000069, GOC:TermGenie, GOC:vw] -synonym: "monosaccharide transport" RELATED [] -is_a: GO:0034219 ! carbohydrate transmembrane transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:35381 ! monosaccharide -intersection_of: results_in_transport_across GO:0016020 ! membrane -relationship: has_primary_input CHEBI:35381 ! monosaccharide -created_by: vw -creation_date: 2017-02-19T10:41:27Z +intersection_of: has_primary_input CHEBI:3098 +relationship: has_primary_input CHEBI:3098 [Term] id: GO:0015774 name: polysaccharide transport namespace: biological_process def: "The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:ai] -is_a: GO:0008643 ! carbohydrate transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:18154 ! polysaccharide -relationship: has_primary_input CHEBI:18154 ! polysaccharide +intersection_of: has_primary_input CHEBI:18154 +relationship: has_primary_input CHEBI:18154 relationship: part_of GO:0033037 ! polysaccharide localization [Term] @@ -69035,21 +57191,18 @@ def: "The directed movement of acidic amino acids, amino acids with a pH below 7 is_a: GO:0006865 ! amino acid transport [Term] -id: GO:0015804 -name: neutral amino acid transport +id: GO:0015802 +name: basic amino acid transport namespace: biological_process -def: "The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +def: "The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0006865 ! amino acid transport [Term] -id: GO:0015807 -name: L-amino acid transport +id: GO:0015804 +name: neutral amino acid transport namespace: biological_process -def: "The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, GOC:jsg, GOC:mah] -is_a: GO:0071702 ! organic substance transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:59869 ! L-alpha-amino acid zwitterion -relationship: has_primary_input CHEBI:59869 ! L-alpha-amino acid zwitterion +def: "The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0006865 ! amino acid transport [Term] id: GO:0015812 @@ -69060,10 +57213,24 @@ comment: See also the biological process term 'neurotransmitter transport ; GO:0 synonym: "4-aminobutanoate transport" EXACT [] synonym: "4-aminobutyrate transport" EXACT [] synonym: "GABA transport" EXACT [] -is_a: GO:0071702 ! organic substance transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:59888 ! gamma-aminobutyric acid zwitterion -relationship: has_primary_input CHEBI:59888 ! gamma-aminobutyric acid zwitterion +intersection_of: has_primary_input CHEBI:59888 +relationship: has_primary_input CHEBI:59888 + +[Term] +id: GO:0015813 +name: L-glutamate transmembrane transport +namespace: biological_process +alt_id: GO:0089711 +def: "The directed movement of L-glutamate across a membrane." [PMID:21307582] +synonym: "L-glutamate transport" BROAD [] +synonym: "mitochondrial aspartate/glutamate transport" RELATED [] +is_a: GO:0003333 ! amino acid transmembrane transport +is_a: GO:0051938 ! L-glutamate import +intersection_of: GO:0015800 ! acidic amino acid transport +intersection_of: has_primary_input CHEBI:29985 +intersection_of: results_in_transport_across GO:0016020 ! membrane [Term] id: GO:0015816 @@ -69072,8 +57239,8 @@ namespace: biological_process def: "The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0015804 ! neutral amino acid transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:57305 ! glycine zwitterion -relationship: has_primary_input CHEBI:57305 ! glycine zwitterion +intersection_of: has_primary_input CHEBI:57305 +relationship: has_primary_input CHEBI:57305 [Term] id: GO:0015833 @@ -69084,8 +57251,8 @@ subset: goslim_pir is_a: GO:0042886 ! amide transport is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:16670 ! peptide -relationship: has_primary_input CHEBI:16670 ! peptide +intersection_of: has_primary_input CHEBI:16670 +relationship: has_primary_input CHEBI:16670 [Term] id: GO:0015837 @@ -69094,23 +57261,10 @@ namespace: biological_process def: "The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, ISBN:0198506732] subset: goslim_pir synonym: "amine/polyamine transport" RELATED [] -is_a: GO:0071702 ! organic substance transport -is_a: GO:0071705 ! nitrogen compound transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:32952 ! amine -relationship: has_primary_input CHEBI:32952 ! amine - -[Term] -id: GO:0015844 -name: monoamine transport -namespace: biological_process -alt_id: GO:0015873 -def: "The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] -is_a: GO:0071702 ! organic substance transport -is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:63534 ! monoamine -relationship: has_primary_input CHEBI:63534 ! monoamine +intersection_of: has_primary_input CHEBI:32952 +relationship: has_primary_input CHEBI:32952 [Term] id: GO:0015849 @@ -69118,10 +57272,10 @@ name: organic acid transport namespace: biological_process def: "The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [ISBN:0198506732] subset: goslim_pir -is_a: GO:0071702 ! organic substance transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:64709 ! organic acid -relationship: has_primary_input CHEBI:64709 ! organic acid +intersection_of: has_primary_input CHEBI:64709 +relationship: has_primary_input CHEBI:64709 [Term] id: GO:0015850 @@ -69131,42 +57285,28 @@ def: "The directed movement of an organic hydroxy compound (organic alcohol) int synonym: "organic alcohol transport" EXACT [] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:33822 ! organic hydroxy compound -relationship: has_primary_input CHEBI:33822 ! organic hydroxy compound - -[Term] -id: GO:0015851 -name: nucleobase transport -namespace: biological_process -def: "The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [ISBN:0198506732] -synonym: "nucleobase transmembrane transport" EXACT [GOC:mah] -is_a: GO:0071702 ! organic substance transport -is_a: GO:0071705 ! nitrogen compound transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:18282 ! nucleobase -relationship: has_primary_input CHEBI:18282 ! nucleobase +intersection_of: has_primary_input CHEBI:33822 +relationship: has_primary_input CHEBI:33822 [Term] id: GO:0015870 name: acetylcholine transport namespace: biological_process def: "The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai] -is_a: GO:0015695 ! organic cation transport -is_a: GO:0071705 ! nitrogen compound transport -is_a: GO:1901374 ! acetate ester transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:15355 ! acetylcholine -relationship: has_primary_input CHEBI:15355 ! acetylcholine +intersection_of: has_primary_input CHEBI:15355 +relationship: has_primary_input CHEBI:15355 [Term] id: GO:0015872 name: dopamine transport namespace: biological_process def: "The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." [GOC:ai] -is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:59905 ! dopaminium(1+) -relationship: has_primary_input CHEBI:59905 ! dopaminium(1+) +intersection_of: has_primary_input CHEBI:59905 +relationship: has_primary_input CHEBI:59905 [Term] id: GO:0015874 @@ -69175,55 +57315,10 @@ namespace: biological_process def: "The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." [GOC:ai, ISBN:0198506732] synonym: "levarterenol transport" EXACT [] synonym: "noradrenaline transport" EXACT [] -is_a: GO:0015695 ! organic cation transport is_a: GO:0051937 ! catecholamine transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) -relationship: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) - -[Term] -id: GO:0015895 -name: alkane transport -namespace: biological_process -def: "The directed movement of alkanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanes are saturated aliphatic hydrocarbon compounds." [GOC:ai] -is_a: GO:0071702 ! organic substance transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:18310 ! alkane -relationship: has_primary_input CHEBI:18310 ! alkane - -[Term] -id: GO:0015908 -name: fatty acid transport -namespace: biological_process -def: "The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis." [GOC:ai] -is_a: GO:0006869 ! lipid transport -is_a: GO:0015718 ! monocarboxylic acid transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:28868 ! fatty acid anion -relationship: has_primary_input CHEBI:28868 ! fatty acid anion - -[Term] -id: GO:0015912 -name: short-chain fatty acid transport -namespace: biological_process -def: "The directed movement of short-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Short-chain fatty acids are fatty acids with a chain length of less than C6." [GOC:ai] -is_a: GO:0015908 ! fatty acid transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:58951 ! short-chain fatty acid anion -relationship: has_primary_input CHEBI:58951 ! short-chain fatty acid anion - -[Term] -id: GO:0015913 -name: short-chain fatty acid transmembrane transport -namespace: biological_process -def: "The directed movement of short-chain fatty acids into a cell or organelle. Short-chain fatty acids are fatty acids with a chain length of less than C6." [GOC:ai] -synonym: "short-chain fatty acid import" RELATED [] -synonym: "short-chain fatty acid uptake" EXACT [] -is_a: GO:0015912 ! short-chain fatty acid transport -is_a: GO:1902001 ! fatty acid transmembrane transport -intersection_of: GO:0055085 ! transmembrane transport -intersection_of: has_primary_input CHEBI:58951 ! short-chain fatty acid anion -property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24587" xsd:anyURI +intersection_of: has_primary_input CHEBI:72587 +relationship: has_primary_input CHEBI:72587 [Term] id: GO:0015931 @@ -69233,11 +57328,10 @@ def: "The directed movement of nucleobases, nucleosides, nucleotides and nucleic subset: goslim_pir subset: goslim_yeast synonym: "nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb] -is_a: GO:0071702 ! organic substance transport -is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity -relationship: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity +intersection_of: has_primary_input CHEBI:61120 +relationship: has_primary_input CHEBI:61120 [Term] id: GO:0015932 @@ -69247,38 +57341,10 @@ def: "Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic synonym: "nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity" RELATED [GOC:dph, GOC:tb] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity -relationship: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity +intersection_of: has_primary_input CHEBI:61120 +relationship: has_primary_input CHEBI:61120 relationship: part_of GO:0015931 ! nucleobase-containing compound transport -[Term] -id: GO:0015942 -name: formate metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid." [ISBN:0198506732] -synonym: "formate metabolism" EXACT [] -is_a: GO:0032787 ! monocarboxylic acid metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:15740 ! formate -relationship: has_primary_input_or_output CHEBI:15740 ! formate - -[Term] -id: GO:0015943 -name: formate biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid." [ISBN:0198506732] -synonym: "formate anabolism" EXACT [] -synonym: "formate biosynthesis" EXACT [] -synonym: "formate formation" EXACT [] -synonym: "formate synthesis" EXACT [] -synonym: "formic acid biosynthesis" EXACT [] -synonym: "formic acid biosynthetic process" EXACT [] -is_a: GO:0015942 ! formate metabolic process -is_a: GO:0072330 ! monocarboxylic acid biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:15740 ! formate -relationship: has_primary_output CHEBI:15740 ! formate - [Term] id: GO:0015979 name: photosynthesis @@ -69345,10 +57411,10 @@ synonym: "multicellular organism lipid catabolic process" NARROW [] synonym: "multicellular organismal lipid catabolic process" NARROW [] xref: Wikipedia:Lipid_catabolism is_a: GO:0006629 ! lipid metabolic process -is_a: GO:1901575 ! organic substance catabolic process +is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:18059 ! lipid -relationship: has_primary_input CHEBI:18059 ! lipid +intersection_of: has_primary_input CHEBI:18059 +relationship: has_primary_input CHEBI:18059 [Term] id: GO:0016043 @@ -69434,10 +57500,10 @@ synonym: "carbohydrate biosynthesis" EXACT [] synonym: "carbohydrate formation" EXACT [] synonym: "carbohydrate synthesis" EXACT [] is_a: GO:0005975 ! carbohydrate metabolic process -is_a: GO:1901576 ! organic substance biosynthetic process +is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:16646 ! carbohydrate -relationship: has_primary_output CHEBI:16646 ! carbohydrate +intersection_of: has_primary_output CHEBI:16646 +relationship: has_primary_output CHEBI:16646 [Term] id: GO:0016052 @@ -69455,10 +57521,10 @@ synonym: "catabolic carbohydrate metabolism" EXACT [] synonym: "multicellular organismal carbohydrate catabolic process" NARROW [] synonym: "single-organism carbohydrate catabolic process" RELATED [] is_a: GO:0005975 ! carbohydrate metabolic process -is_a: GO:1901575 ! organic substance catabolic process +is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:16646 ! carbohydrate -relationship: has_primary_input CHEBI:16646 ! carbohydrate +intersection_of: has_primary_input CHEBI:16646 +relationship: has_primary_input CHEBI:16646 created_by: jl creation_date: 2012-10-23T16:34:39Z @@ -69476,8 +57542,8 @@ is_a: GO:0044249 ! cellular biosynthetic process is_a: GO:0044283 ! small molecule biosynthetic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:64709 ! organic acid -relationship: has_primary_output CHEBI:64709 ! organic acid +intersection_of: has_primary_output CHEBI:64709 +relationship: has_primary_output CHEBI:64709 [Term] id: GO:0016054 @@ -69490,10 +57556,9 @@ synonym: "organic acid degradation" EXACT [] is_a: GO:0006082 ! organic acid metabolic process is_a: GO:0044248 ! cellular catabolic process is_a: GO:0044282 ! small molecule catabolic process -is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:64709 ! organic acid -relationship: has_primary_input CHEBI:64709 ! organic acid +intersection_of: has_primary_input CHEBI:64709 +relationship: has_primary_input CHEBI:64709 [Term] id: GO:0016057 @@ -69525,10 +57590,10 @@ subset: goslim_metagenomics subset: goslim_pir subset: prokaryote_subset synonym: "RNA metabolism" EXACT [] -is_a: GO:0090304 ! nucleic acid metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:33697 ! ribonucleic acid -relationship: has_primary_input_or_output CHEBI:33697 ! ribonucleic acid +intersection_of: has_primary_input_or_output CHEBI:33697 +relationship: has_primary_input_or_output CHEBI:33697 [Term] id: GO:0016079 @@ -69546,65 +57611,6 @@ relationship: occurs_in GO:0098793 ! presynapse relationship: part_of GO:0007269 ! neurotransmitter secretion relationship: part_of GO:0099504 ! synaptic vesicle cycle -[Term] -id: GO:0016106 -name: sesquiterpenoid biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units." [GOC:go_curators] -synonym: "sesquiterpenoid anabolism" EXACT [] -synonym: "sesquiterpenoid biosynthesis" EXACT [] -synonym: "sesquiterpenoid formation" EXACT [] -synonym: "sesquiterpenoid synthesis" EXACT [] -is_a: GO:0006714 ! sesquiterpenoid metabolic process -is_a: GO:0016114 ! terpenoid biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:26658 ! sesquiterpenoid -relationship: has_primary_output CHEBI:26658 ! sesquiterpenoid - -[Term] -id: GO:0016107 -name: sesquiterpenoid catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units." [GOC:go_curators] -synonym: "sesquiterpenoid breakdown" EXACT [] -synonym: "sesquiterpenoid catabolism" EXACT [] -synonym: "sesquiterpenoid degradation" EXACT [] -is_a: GO:0006714 ! sesquiterpenoid metabolic process -is_a: GO:0016115 ! terpenoid catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:26658 ! sesquiterpenoid -relationship: has_primary_input CHEBI:26658 ! sesquiterpenoid - -[Term] -id: GO:0016114 -name: terpenoid biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure." [GOC:ai] -synonym: "terpenoid anabolism" EXACT [] -synonym: "terpenoid biosynthesis" EXACT [] -synonym: "terpenoid formation" EXACT [] -synonym: "terpenoid synthesis" EXACT [] -xref: Wikipedia:Terpenoid -is_a: GO:0006721 ! terpenoid metabolic process -is_a: GO:0008299 ! isoprenoid biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:26873 ! terpenoid -relationship: has_primary_output CHEBI:26873 ! terpenoid - -[Term] -id: GO:0016115 -name: terpenoid catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure." [GOC:ai] -synonym: "terpenoid breakdown" EXACT [] -synonym: "terpenoid catabolism" EXACT [] -synonym: "terpenoid degradation" EXACT [] -is_a: GO:0006721 ! terpenoid metabolic process -is_a: GO:0008300 ! isoprenoid catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:26873 ! terpenoid -relationship: has_primary_input CHEBI:26873 ! terpenoid - [Term] id: GO:0016192 name: vesicle-mediated transport @@ -69833,9 +57839,10 @@ is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus- id: GO:0016477 name: cell migration namespace: biological_process -def: "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms." [GOC:cjm, GOC:dph, GOC:ems, GOC:pf, Wikipedia:Cell_migration] +def: "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues." [GOC:cjm, GOC:dph, GOC:ems, GOC:pf, Wikipedia:Cell_migration] xref: Wikipedia:Cell_migration is_a: GO:0048870 ! cell motility +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24787" xsd:anyURI [Term] id: GO:0016485 @@ -69856,12 +57863,11 @@ id: GO:0016486 name: peptide hormone processing namespace: biological_process def: "The generation of a mature peptide hormone by posttranslational processing of a prohormone." [GOC:mah] -is_a: GO:0006518 ! peptide metabolic process is_a: GO:0042445 ! hormone metabolic process is_a: GO:0140448 ! signaling receptor ligand precursor processing intersection_of: GO:0016485 ! protein processing -intersection_of: has_primary_input_or_output CHEBI:25905 ! peptide hormone -relationship: has_primary_input_or_output CHEBI:25905 ! peptide hormone +intersection_of: has_primary_input_or_output CHEBI:25905 +relationship: has_primary_input_or_output CHEBI:25905 [Term] id: GO:0016500 @@ -69931,8 +57937,8 @@ synonym: "aminoethanoic acid binding" EXACT [] synonym: "Gly binding" EXACT [] is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:57305 ! glycine zwitterion -relationship: has_input CHEBI:57305 ! glycine zwitterion +intersection_of: has_input CHEBI:57305 +relationship: has_input CHEBI:57305 [Term] id: GO:0016595 @@ -69940,10 +57946,10 @@ name: glutamate binding namespace: molecular_function def: "Binding to glutamate, the anion of 2-aminopentanedioic acid." [GOC:ai] synonym: "glutamic acid binding" EXACT [] -is_a: GO:0031406 ! carboxylic acid binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:14321 ! glutamate(1-) -relationship: has_input CHEBI:14321 ! glutamate(1-) +intersection_of: has_input CHEBI:14321 +relationship: has_input CHEBI:14321 [Term] id: GO:0016597 @@ -69952,10 +57958,10 @@ namespace: molecular_function def: "Binding to an amino acid, organic acids containing one or more amino substituents." [GOC:ai] subset: goslim_metagenomics subset: goslim_pir -is_a: GO:0043177 ! organic acid binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:33709 ! amino acid -relationship: has_input CHEBI:33709 ! amino acid +intersection_of: has_input CHEBI:33709 +relationship: has_input CHEBI:33709 [Term] id: GO:0016740 @@ -69979,6 +57985,34 @@ xref: Reactome:R-HSA-5668414 "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2 xref: Reactome:R-HSA-8868783 "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248" is_a: GO:0003824 ! catalytic activity +[Term] +id: GO:0016746 +name: acyltransferase activity +namespace: molecular_function +alt_id: GO:0008415 +def: "Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732] +subset: goslim_chembl +subset: goslim_drosophila +synonym: "transferase activity, transferring acyl groups" EXACT [] +xref: EC:2.3.-.- +xref: Reactome:R-HSA-159431 "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine" +xref: Reactome:R-HSA-192312 "Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate" +xref: Reactome:R-HSA-193491 "Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate" +xref: Reactome:R-HSA-6792572 "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs" +xref: Reactome:R-HSA-8858298 "HRASLS transfer acyl group from PC to PE to form NAPE" +is_a: GO:0016740 ! transferase activity +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI + +[Term] +id: GO:0016755 +name: aminoacyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor)." [GOC:jl] +synonym: "transferase activity, transferring amino-acyl groups" EXACT [] +xref: EC:2.3.2.- +is_a: GO:0016746 ! acyltransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + [Term] id: GO:0016772 name: transferase activity, transferring phosphorus-containing groups @@ -70140,7 +58174,7 @@ is_a: GO:0008227 ! G protein-coupled amine receptor activity is_a: GO:0015464 ! acetylcholine receptor activity is_a: GO:0099528 ! G protein-coupled neurotransmitter receptor activity intersection_of: GO:0004930 ! G protein-coupled receptor activity -intersection_of: has_input CHEBI:15355 ! acetylcholine +intersection_of: has_input CHEBI:15355 relationship: part_of GO:0007213 ! G protein-coupled acetylcholine receptor signaling pathway [Term] @@ -70157,8 +58191,8 @@ synonym: "gamma-aminobutyric acid binding" EXACT [] synonym: "gamma-aminobutyric acid receptor activity" EXACT [] is_a: GO:0004888 ! transmembrane signaling receptor activity intersection_of: GO:0038023 ! signaling receptor activity -intersection_of: has_input CHEBI:59888 ! gamma-aminobutyric acid zwitterion -relationship: has_input CHEBI:59888 ! gamma-aminobutyric acid zwitterion +intersection_of: has_input CHEBI:59888 +relationship: has_input CHEBI:59888 [Term] id: GO:0017046 @@ -70166,30 +58200,10 @@ name: peptide hormone binding namespace: molecular_function def: "Binding to a peptide with hormonal activity in animals." [GOC:jl, ISBN:0198506732] synonym: "polypeptide hormone binding" EXACT [] -is_a: GO:0042277 ! peptide binding is_a: GO:0042562 ! hormone binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:25905 ! peptide hormone -relationship: has_input CHEBI:25905 ! peptide hormone - -[Term] -id: GO:0017080 -name: sodium channel regulator activity -namespace: molecular_function -def: "Binds to and modulates the activity of a sodium channel." [GOC:mah] -is_a: GO:0099106 ! ion channel regulator activity -intersection_of: GO:0098772 ! molecular function regulator activity -intersection_of: directly_regulates GO:0005272 ! sodium channel activity -relationship: directly_regulates GO:0005272 ! sodium channel activity - -[Term] -id: GO:0017085 -name: response to insecticide -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects." [GOC:curators] -synonym: "insecticide resistance" RELATED [] -synonym: "insecticide susceptibility/resistance" RELATED [] -is_a: GO:0009636 ! response to toxic substance +intersection_of: has_input CHEBI:25905 +relationship: has_input CHEBI:25905 [Term] id: GO:0017111 @@ -70262,10 +58276,9 @@ synonym: "negative regulation of protein synthesis" EXACT [] synonym: "protein biosynthesis inhibitor activity" RELATED [] synonym: "protein biosynthetic process inhibitor activity" RELATED [] is_a: GO:0006417 ! regulation of translation +is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0010629 ! negative regulation of gene expression -is_a: GO:0034249 ! negative regulation of amide metabolic process is_a: GO:0051248 ! negative regulation of protein metabolic process -is_a: GO:2000113 ! negative regulation of cellular macromolecule biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006412 ! translation relationship: negatively_regulates GO:0006412 ! translation @@ -70302,8 +58315,8 @@ synonym: "heterocycle synthesis" EXACT [] is_a: GO:0044249 ! cellular biosynthetic process is_a: GO:0046483 ! heterocycle metabolic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:5686 ! heterocyclic compound -relationship: has_primary_output CHEBI:5686 ! heterocyclic compound +intersection_of: has_primary_output CHEBI:5686 +relationship: has_primary_output CHEBI:5686 [Term] id: GO:0018146 @@ -70317,12 +58330,11 @@ synonym: "keratan sulfate synthesis" EXACT [] synonym: "keratan sulphate biosynthesis" EXACT [] synonym: "keratan sulphate biosynthetic process" EXACT [] xref: RESID:AA0247 -is_a: GO:0006024 ! glycosaminoglycan biosynthetic process +is_a: GO:0009058 ! biosynthetic process is_a: GO:0042339 ! keratan sulfate metabolic process -is_a: GO:0044272 ! sulfur compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:60924 ! keratan sulfate -relationship: has_primary_output CHEBI:60924 ! keratan sulfate +intersection_of: has_primary_output CHEBI:60924 +relationship: has_primary_output CHEBI:60924 [Term] id: GO:0018193 @@ -70331,7 +58343,7 @@ namespace: biological_process def: "The alteration of an amino acid residue in a peptide." [GOC:mah] subset: goslim_yeast is_a: GO:0036211 ! protein modification process -relationship: has_input CHEBI:33708 ! amino-acid residue +relationship: has_input CHEBI:33708 [Term] id: GO:0018212 @@ -70356,8 +58368,8 @@ is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901615 ! organic hydroxy compound metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:33853 ! phenols -relationship: has_primary_input_or_output CHEBI:33853 ! phenols +intersection_of: has_primary_input_or_output CHEBI:33853 +relationship: has_primary_input_or_output CHEBI:33853 [Term] id: GO:0019098 @@ -70444,19 +58456,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006629 ! lipid metabolic process relationship: regulates GO:0006629 ! lipid metabolic process -[Term] -id: GO:0019217 -name: regulation of fatty acid metabolic process -namespace: biological_process -alt_id: GO:0006632 -def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids." [GOC:go_curators] -synonym: "regulation of fatty acid metabolism" EXACT [] -is_a: GO:0010565 ! regulation of cellular ketone metabolic process -is_a: GO:0019216 ! regulation of lipid metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0006631 ! fatty acid metabolic process -relationship: regulates GO:0006631 ! fatty acid metabolic process - [Term] id: GO:0019218 name: regulation of steroid metabolic process @@ -70488,7 +58487,7 @@ name: regulation of phosphate metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators] synonym: "regulation of phosphate metabolism" EXACT [] -is_a: GO:0051174 ! regulation of phosphorus metabolic process +is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006796 ! phosphate-containing compound metabolic process relationship: regulates GO:0006796 ! phosphate-containing compound metabolic process @@ -70575,10 +58574,10 @@ name: hexose metabolic process namespace: biological_process def: "The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732] synonym: "hexose metabolism" EXACT [] -is_a: GO:0005996 ! monosaccharide metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:18133 ! hexose -relationship: has_primary_input_or_output CHEBI:18133 ! hexose +intersection_of: has_primary_input_or_output CHEBI:18133 +relationship: has_primary_input_or_output CHEBI:18133 [Term] id: GO:0019319 @@ -70589,11 +58588,11 @@ synonym: "hexose anabolism" EXACT [] synonym: "hexose biosynthesis" EXACT [] synonym: "hexose formation" EXACT [] synonym: "hexose synthesis" EXACT [] +is_a: GO:0009058 ! biosynthetic process is_a: GO:0019318 ! hexose metabolic process -is_a: GO:0046364 ! monosaccharide biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:18133 ! hexose -relationship: has_primary_output CHEBI:18133 ! hexose +intersection_of: has_primary_output CHEBI:18133 +relationship: has_primary_output CHEBI:18133 [Term] id: GO:0019320 @@ -70603,11 +58602,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of hexose, synonym: "hexose breakdown" EXACT [] synonym: "hexose catabolism" EXACT [] synonym: "hexose degradation" EXACT [] +is_a: GO:0009056 ! catabolic process is_a: GO:0019318 ! hexose metabolic process -is_a: GO:0046365 ! monosaccharide catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:18133 ! hexose -relationship: has_primary_input CHEBI:18133 ! hexose +intersection_of: has_primary_input CHEBI:18133 +relationship: has_primary_input CHEBI:18133 [Term] id: GO:0019336 @@ -70618,43 +58617,11 @@ synonym: "phenol-containing compound breakdown" EXACT [] synonym: "phenol-containing compound catabolism" EXACT [] synonym: "phenol-containing compound degradation" EXACT [] xref: MetaCyc:PHENOLDEG-PWY +is_a: GO:0009056 ! catabolic process is_a: GO:0018958 ! phenol-containing compound metabolic process -is_a: GO:0019439 ! aromatic compound catabolic process -is_a: GO:1901361 ! organic cyclic compound catabolic process -is_a: GO:1901616 ! organic hydroxy compound catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:33853 ! phenols -relationship: has_primary_input CHEBI:33853 ! phenols - -[Term] -id: GO:0019377 -name: glycolipid catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide)." [GOC:go_curators] -synonym: "glycolipid breakdown" EXACT [] -synonym: "glycolipid catabolism" EXACT [] -synonym: "glycolipid degradation" EXACT [] -is_a: GO:0006664 ! glycolipid metabolic process -is_a: GO:0046466 ! membrane lipid catabolic process -is_a: GO:1901136 ! carbohydrate derivative catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:33563 ! glycolipid -relationship: has_primary_input CHEBI:33563 ! glycolipid - -[Term] -id: GO:0019413 -name: acetate biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid." [GOC:go_curators] -synonym: "acetate anabolism" EXACT [] -synonym: "acetate biosynthesis" EXACT [] -synonym: "acetate formation" EXACT [] -synonym: "acetate synthesis" EXACT [] -is_a: GO:0006083 ! acetate metabolic process -is_a: GO:0072330 ! monocarboxylic acid biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:30089 ! acetate -relationship: has_primary_output CHEBI:30089 ! acetate +intersection_of: has_primary_input CHEBI:33853 +relationship: has_primary_input CHEBI:33853 [Term] id: GO:0019438 @@ -70670,8 +58637,8 @@ synonym: "aromatic hydrocarbon biosynthetic process" NARROW [] is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0044249 ! cellular biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:33655 ! aromatic compound -relationship: has_primary_output CHEBI:33655 ! aromatic compound +intersection_of: has_primary_output CHEBI:33655 +relationship: has_primary_output CHEBI:33655 [Term] id: GO:0019439 @@ -70686,8 +58653,8 @@ synonym: "aromatic hydrocarbon catabolism" NARROW [] is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0044248 ! cellular catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:33655 ! aromatic compound -relationship: has_primary_input CHEBI:33655 ! aromatic compound +intersection_of: has_primary_input CHEBI:33655 +relationship: has_primary_input CHEBI:33655 [Term] id: GO:0019538 @@ -70709,30 +58676,12 @@ synonym: "protein metabolic process and modification" EXACT [] synonym: "protein metabolism" EXACT [] synonym: "protein metabolism and modification" EXACT [] xref: Wikipedia:Protein_metabolism -is_a: GO:0043170 ! macromolecule metabolic process is_a: GO:0044238 ! primary metabolic process -is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output PR:000000001 ! protein relationship: has_primary_input_or_output PR:000000001 ! protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI -[Term] -id: GO:0019605 -name: butyrate metabolic process -namespace: biological_process -alt_id: GO:0043437 -def: "The chemical reactions and pathways involving any butyrate, the anions of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid." [ISBN:0198506732] -synonym: "butanoic acid metabolic process" EXACT [] -synonym: "butanoic acid metabolism" EXACT [] -synonym: "butyrate metabolism" EXACT [] -synonym: "butyric acid metabolic process" EXACT [] -synonym: "butyric acid metabolism" EXACT [] -is_a: GO:0046459 ! short-chain fatty acid metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:17968 ! butyrate -relationship: has_primary_input_or_output CHEBI:17968 ! butyrate - [Term] id: GO:0019614 name: catechol-containing compound catabolic process @@ -70742,51 +58691,11 @@ synonym: "catechol breakdown" RELATED [] synonym: "catechol catabolic process" RELATED [] synonym: "catechol catabolism" RELATED [] synonym: "catechol degradation" RELATED [] +is_a: GO:0009056 ! catabolic process is_a: GO:0009712 ! catechol-containing compound metabolic process -is_a: GO:0019336 ! phenol-containing compound catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:33566 ! catechols -relationship: has_primary_input CHEBI:33566 ! catechols - -[Term] -id: GO:0019626 -name: short-chain fatty acid catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of fatty acids with a chain length of less than C6." [ISBN:0198506732] -synonym: "short-chain fatty acid breakdown" EXACT [] -synonym: "short-chain fatty acid catabolism" EXACT [] -synonym: "short-chain fatty acid degradation" EXACT [] -xref: MetaCyc:ACETOACETATE-DEG-PWY -is_a: GO:0009062 ! fatty acid catabolic process -is_a: GO:0046459 ! short-chain fatty acid metabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:58951 ! short-chain fatty acid anion -relationship: has_primary_input CHEBI:58951 ! short-chain fatty acid anion - -[Term] -id: GO:0019654 -name: acetate fermentation -namespace: biological_process -def: "The anaerobic chemical reactions and pathways resulting in the breakdown of acetate, yielding energy in the form of ATP." [GOC:jl, MetaCyc:P142-PWY] -xref: MetaCyc:P142-PWY -is_a: GO:0006083 ! acetate metabolic process -is_a: GO:0006113 ! fermentation -intersection_of: GO:0006113 ! fermentation -intersection_of: has_primary_input CHEBI:30089 ! acetate -relationship: has_primary_input CHEBI:30089 ! acetate -relationship: never_in_taxon NCBITaxon:4895 ! Schizosaccharomyces - -[Term] -id: GO:0019666 -name: nitrogenous compound fermentation -namespace: biological_process -def: "The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP." [GOC:mah] -synonym: "nitrogenous compound catabolic process" BROAD [] -is_a: GO:0006113 ! fermentation -is_a: GO:0006807 ! nitrogen compound metabolic process -intersection_of: GO:0006113 ! fermentation -intersection_of: has_primary_input CHEBI:51143 ! nitrogen molecular entity -relationship: has_primary_input CHEBI:51143 ! nitrogen molecular entity +intersection_of: has_primary_input CHEBI:33566 +relationship: has_primary_input CHEBI:33566 [Term] id: GO:0019722 @@ -70842,18 +58751,6 @@ def: "An immune response against microbes mediated through a body fluid. Example is_a: GO:0006959 ! humoral immune response is_a: GO:0098542 ! defense response to other organism -[Term] -id: GO:0019747 -name: regulation of isoprenoid metabolic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids." [GOC:go_curators] -synonym: "regulation of isoprenoid metabolism" EXACT [] -is_a: GO:0019216 ! regulation of lipid metabolic process -is_a: GO:0031323 ! regulation of cellular metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0006720 ! isoprenoid metabolic process -relationship: regulates GO:0006720 ! isoprenoid metabolic process - [Term] id: GO:0019748 name: secondary metabolic process @@ -70877,19 +58774,8 @@ def: "The chemical reactions and pathways involving carboxylic acids, any organi synonym: "carboxylic acid metabolism" EXACT [] is_a: GO:0043436 ! oxoacid metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:29067 ! carboxylic acid anion -relationship: has_primary_input_or_output CHEBI:29067 ! carboxylic acid anion - -[Term] -id: GO:0019755 -name: one-carbon compound transport -namespace: biological_process -def: "The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] -synonym: "one carbon compound transport" EXACT [] -is_a: GO:0071702 ! organic substance transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:64708 ! one-carbon compound -relationship: has_primary_input CHEBI:64708 ! one-carbon compound +intersection_of: has_primary_input_or_output CHEBI:29067 +relationship: has_primary_input_or_output CHEBI:29067 [Term] id: GO:0019777 @@ -70963,8 +58849,8 @@ synonym: "ubiquitin-like conjugating enzyme activity" NARROW [] synonym: "ubiquitin-like-protein ligase activity" NARROW [] xref: Reactome:R-HSA-5678490 "ATG16L1 complex transfers LC3 from ATG3 to PE" xref: Reactome:R-HSA-688137 "RIP2 is K63 polyubiquitinated" -is_a: GO:0016740 ! transferase activity -is_a: GO:0140096 ! catalytic activity, acting on a protein +is_a: GO:0016755 ! aminoacyltransferase activity +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24697" xsd:anyURI [Term] id: GO:0019814 @@ -71004,8 +58890,8 @@ synonym: "cytochrome P450" NARROW [] synonym: "cytochrome P450 activity" RELATED [] is_a: GO:0036094 ! small molecule binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:15379 ! dioxygen -relationship: has_input CHEBI:15379 ! dioxygen +intersection_of: has_input CHEBI:15379 +relationship: has_input CHEBI:15379 [Term] id: GO:0019827 @@ -71019,24 +58905,13 @@ intersection_of: GO:0098727 ! maintenance of cell number intersection_of: acts_on_population_of CL:0000034 ! stem cell relationship: acts_on_population_of CL:0000034 ! stem cell -[Term] -id: GO:0019840 -name: isoprenoid binding -namespace: molecular_function -def: "Binding to an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." [GOC:jl] -subset: goslim_pir -is_a: GO:0008289 ! lipid binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:24913 ! isoprenoid -relationship: has_input CHEBI:24913 ! isoprenoid - [Term] id: GO:0019855 name: calcium channel inhibitor activity namespace: molecular_function def: "Binds to and stops, prevents, or reduces the activity of a calcium channel." [GOC:mah] is_a: GO:0005246 ! calcium channel regulator activity -is_a: GO:0008200 ! ion channel inhibitor activity +is_a: GO:0016248 ! channel inhibitor activity intersection_of: GO:0098772 ! molecular function regulator activity intersection_of: directly_negatively_regulates GO:0005262 ! calcium channel activity relationship: directly_negatively_regulates GO:0005262 ! calcium channel activity @@ -71049,18 +58924,6 @@ def: "The external membrane of Gram-negative bacteria or certain organelles such subset: goslim_metagenomics is_a: GO:0016020 ! membrane -[Term] -id: GO:0019871 -name: sodium channel inhibitor activity -namespace: molecular_function -alt_id: GO:0019868 -def: "Binds to and stops, prevents, or reduces the activity of a sodium channel." [GOC:mah] -is_a: GO:0008200 ! ion channel inhibitor activity -is_a: GO:0017080 ! sodium channel regulator activity -intersection_of: GO:0098772 ! molecular function regulator activity -intersection_of: directly_negatively_regulates GO:0005272 ! sodium channel activity -relationship: directly_negatively_regulates GO:0005272 ! sodium channel activity - [Term] id: GO:0019882 name: antigen processing and presentation @@ -73764,17 +61627,6 @@ xref: Reactome:R-HSA-429767 "Passive I- efflux mediated by SMCT1" xref: Wikipedia:Facilitated_diffusion is_a: GO:0022857 ! transmembrane transporter activity -[Term] -id: GO:0022804 -name: active transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport, ISBN:0815340729] -synonym: "active carrier activity" EXACT [] -synonym: "carrier activity" EXACT [] -synonym: "permease activity" EXACT [] -synonym: "pump activity" EXACT [] -is_a: GO:0022857 ! transmembrane transporter activity - [Term] id: GO:0022824 name: transmitter-gated monoatomic ion channel activity @@ -73828,7 +61680,7 @@ synonym: "ion gated channel activity" BROAD [] is_a: GO:0005216 ! monoatomic ion channel activity is_a: GO:0022836 ! gated channel activity intersection_of: GO:0022836 ! gated channel activity -intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion +intersection_of: has_primary_input CHEBI:24867 [Term] id: GO:0022843 @@ -73838,10 +61690,10 @@ def: "Enables the transmembrane transfer of a cation by a voltage-gated channel. synonym: "voltage-gated cation channel activity" BROAD [] xref: Reactome:R-HSA-2534378 "Hv1 Mediated H+ Permeability" xref: Reactome:R-HSA-6788999 "HV1-mediated H+ transfer" -is_a: GO:0005244 ! voltage-gated monoatomic ion channel activity is_a: GO:0005261 ! monoatomic cation channel activity +is_a: GO:0022832 ! voltage-gated channel activity intersection_of: GO:0022832 ! voltage-gated channel activity -intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation +intersection_of: has_primary_input CHEBI:23906 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI [Term] @@ -73862,7 +61714,7 @@ is_a: GO:0005231 ! excitatory extracellular ligand-gated monoatomic ion channel is_a: GO:0099094 ! ligand-gated monoatomic cation channel activity is_a: GO:1904315 ! transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential intersection_of: GO:0022834 ! ligand-gated channel activity -intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation +intersection_of: has_primary_input CHEBI:23906 intersection_of: regulated_by GO:0042166 ! acetylcholine binding relationship: regulated_by GO:0042166 ! acetylcholine binding @@ -73883,23 +61735,11 @@ is_a: GO:0022824 ! transmitter-gated monoatomic ion channel activity is_a: GO:0099094 ! ligand-gated monoatomic cation channel activity is_a: GO:0099589 ! serotonin receptor activity intersection_of: GO:0022834 ! ligand-gated channel activity -intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation +intersection_of: has_primary_input CHEBI:23906 intersection_of: regulated_by GO:0051378 ! serotonin binding relationship: part_of GO:0007210 ! serotonin receptor signaling pathway relationship: regulated_by GO:0051378 ! serotonin binding -[Term] -id: GO:0022853 -name: active monoatomic ion transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport, ISBN:0815340729] -synonym: "active ion transmembrane transporter activity" BROAD [] -is_a: GO:0015075 ! monoatomic ion transmembrane transporter activity -is_a: GO:0022804 ! active transmembrane transporter activity -intersection_of: GO:0022804 ! active transmembrane transporter activity -intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion -property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI - [Term] id: GO:0022857 name: transmembrane transporter activity @@ -73936,26 +61776,8 @@ namespace: molecular_function def: "Enables the transfer of a macromolecule from one side of a membrane to the other." [GOC:mtg_transport, ISBN:0815340729] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:33694 ! biomacromolecule -relationship: has_primary_input CHEBI:33694 ! biomacromolecule - -[Term] -id: GO:0022890 -name: inorganic cation transmembrane transporter activity -namespace: molecular_function -alt_id: GO:0015077 -alt_id: GO:0015082 -alt_id: GO:0072509 -alt_id: GO:0072510 -def: "Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] -synonym: "di-, tri-valent inorganic cation transmembrane transporter activity" NARROW [GOC:mah] -synonym: "divalent inorganic cation transmembrane transporter activity" NARROW [] -synonym: "monovalent inorganic cation transmembrane transporter activity" NARROW [] -synonym: "trivalent inorganic cation transmembrane transporter activity" NARROW [] -is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:36915 ! inorganic cation -relationship: has_primary_input CHEBI:36915 ! inorganic cation +intersection_of: has_primary_input CHEBI:33694 +relationship: has_primary_input CHEBI:33694 [Term] id: GO:0022898 @@ -74043,7 +61865,7 @@ synonym: "signaling process" EXACT [] synonym: "signalling" EXACT [] synonym: "signalling process" RELATED [GOC:mah] synonym: "single organism signaling" RELATED [] -is_a: GO:0008150 ! biological_process +is_a: GO:0050789 ! regulation of biological process created_by: jl creation_date: 2010-02-16T09:30:50Z @@ -74087,25 +61909,6 @@ intersection_of: part_of GO:0007267 ! cell-cell signaling relationship: part_of GO:0007267 ! cell-cell signaling creation_date: 2010-02-16T09:30:50Z -[Term] -id: GO:0030001 -name: metal ion transport -namespace: biological_process -alt_id: GO:0070838 -alt_id: GO:0070839 -def: "The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] -synonym: "divalent metal ion export" NARROW [] -synonym: "divalent metal ion transport" NARROW [] -synonym: "heavy metal ion transport" NARROW [] -synonym: "metal ion export" NARROW [] -is_a: GO:0006812 ! monoatomic cation transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:25213 ! metal cation -relationship: has_primary_input CHEBI:25213 ! metal cation -property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23033" xsd:anyURI -created_by: mah -creation_date: 2009-07-31T01:07:46Z - [Term] id: GO:0030003 name: intracellular monoatomic cation homeostasis @@ -74113,10 +61916,10 @@ namespace: biological_process def: "A homeostatic process involved in the maintenance of a steady state level of monoatomic cations within a cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom." [GOC:ceb, GOC:mah] synonym: "cellular cation homeostasis" BROAD [] synonym: "cellular monoatomic cation homeostasis" EXACT [] -is_a: GO:0006873 ! intracellular monoatomic ion homeostasis -is_a: GO:0055080 ! monoatomic cation homeostasis +is_a: GO:0019725 ! cellular homeostasis intersection_of: GO:0019725 ! cellular homeostasis -intersection_of: regulates_levels_of CHEBI:23906 ! monoatomic cation +intersection_of: regulates_levels_of CHEBI:23906 +relationship: regulates_levels_of CHEBI:23906 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24455" xsd:anyURI [Term] @@ -74266,8 +62069,8 @@ def: "The regulated release of a peptide hormone from a cell." [GOC:mah] is_a: GO:0002790 ! peptide secretion is_a: GO:0046879 ! hormone secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:25905 ! peptide hormone -relationship: has_primary_input CHEBI:25905 ! peptide hormone +intersection_of: has_primary_input CHEBI:25905 +relationship: has_primary_input CHEBI:25905 [Term] id: GO:0030073 @@ -74355,22 +62158,8 @@ namespace: biological_process def: "The regulated release of vasopressin from secretory granules into the blood." [GOC:mah] is_a: GO:0030072 ! peptide hormone secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:9937 ! vasopressin -relationship: has_primary_input CHEBI:9937 ! vasopressin - -[Term] -id: GO:0030104 -name: water homeostasis -namespace: biological_process -alt_id: GO:0018987 -def: "Any process involved in the maintenance of an internal steady state of water within an organism or cell." [GOC:dph, GOC:mah, GOC:tb] -synonym: "osmoregulation" RELATED [] -synonym: "regulation of osmotic pressure" EXACT [] -xref: Wikipedia:Osmoregulation -is_a: GO:0048878 ! chemical homeostasis -intersection_of: GO:0048878 ! chemical homeostasis -intersection_of: regulates_levels_of CHEBI:15377 ! water -relationship: regulates_levels_of CHEBI:15377 ! water +intersection_of: has_primary_input CHEBI:9937 +relationship: has_primary_input CHEBI:9937 [Term] id: GO:0030133 @@ -74407,43 +62196,11 @@ is_a: GO:0099503 ! secretory vesicle relationship: never_in_taxon NCBITaxon:4890 ! Ascomycota relationship: part_of GO:0012505 ! endomembrane system -[Term] -id: GO:0030148 -name: sphingolipid biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [GOC:mah, ISBN:0198506732] -synonym: "sphingolipid anabolism" EXACT [] -synonym: "sphingolipid biosynthesis" EXACT [] -synonym: "sphingolipid formation" EXACT [] -synonym: "sphingolipid synthesis" EXACT [] -xref: MetaCyc:PWY-5129 -is_a: GO:0006665 ! sphingolipid metabolic process -is_a: GO:0046467 ! membrane lipid biosynthetic process -is_a: GO:1901566 ! organonitrogen compound biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:26739 ! sphingolipid -relationship: has_primary_output CHEBI:26739 ! sphingolipid - -[Term] -id: GO:0030149 -name: sphingolipid catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [GOC:mah, ISBN:0198506732] -synonym: "sphingolipid breakdown" EXACT [] -synonym: "sphingolipid catabolism" EXACT [] -synonym: "sphingolipid degradation" EXACT [] -is_a: GO:0006665 ! sphingolipid metabolic process -is_a: GO:0046466 ! membrane lipid catabolic process -is_a: GO:1901565 ! organonitrogen compound catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:26739 ! sphingolipid -relationship: has_primary_input CHEBI:26739 ! sphingolipid - [Term] id: GO:0030154 name: cell differentiation namespace: biological_process -def: "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [ISBN:0198506732] +def: "The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [ISBN:0198506732] subset: goslim_agr subset: goslim_chembl subset: goslim_drosophila @@ -74455,6 +62212,7 @@ is_a: GO:0048869 ! cellular developmental process intersection_of: GO:0048869 ! cellular developmental process intersection_of: results_in_acquisition_of_features_of CL:0000000 ! cell relationship: results_in_acquisition_of_features_of CL:0000000 ! cell +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI [Term] id: GO:0030155 @@ -74502,9 +62260,8 @@ synonym: "protein breakdown" EXACT [] synonym: "protein catabolism" EXACT [] synonym: "protein degradation" EXACT [] xref: Wikipedia:Protein_catabolism -is_a: GO:0009057 ! macromolecule catabolic process +is_a: GO:0009056 ! catabolic process is_a: GO:0019538 ! protein metabolic process -is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input PR:000000001 ! protein relationship: has_primary_input PR:000000001 ! protein @@ -74520,10 +62277,10 @@ synonym: "proteoglycan biosynthesis" EXACT [] synonym: "proteoglycan formation" EXACT [] synonym: "proteoglycan synthesis" EXACT [] is_a: GO:0006029 ! proteoglycan metabolic process -is_a: GO:0009101 ! glycoprotein biosynthetic process +is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:37396 ! proteoglycan -relationship: has_primary_output CHEBI:37396 ! proteoglycan +intersection_of: has_primary_output CHEBI:37396 +relationship: has_primary_output CHEBI:37396 [Term] id: GO:0030167 @@ -74534,10 +62291,10 @@ synonym: "proteoglycan breakdown" EXACT [] synonym: "proteoglycan catabolism" EXACT [] synonym: "proteoglycan degradation" EXACT [] is_a: GO:0006029 ! proteoglycan metabolic process -is_a: GO:0006516 ! glycoprotein catabolic process +is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:37396 ! proteoglycan -relationship: has_primary_input CHEBI:37396 ! proteoglycan +intersection_of: has_primary_input CHEBI:37396 +relationship: has_primary_input CHEBI:37396 [Term] id: GO:0030168 @@ -74584,10 +62341,10 @@ id: GO:0030184 name: nitric oxide transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of nitric oxide, nitrogen monoxide, from one side of a membrane to the other." [GOC:mah] -is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity +is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:16480 ! nitric oxide -relationship: has_primary_input CHEBI:16480 ! nitric oxide +intersection_of: has_primary_input CHEBI:16480 +relationship: has_primary_input CHEBI:16480 relationship: part_of GO:0030185 ! nitric oxide transport [Term] @@ -74595,10 +62352,10 @@ id: GO:0030185 name: nitric oxide transport namespace: biological_process def: "The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] -is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:16480 ! nitric oxide -relationship: has_primary_input CHEBI:16480 ! nitric oxide +intersection_of: has_primary_input CHEBI:16480 +relationship: has_primary_input CHEBI:16480 [Term] id: GO:0030186 @@ -74610,8 +62367,8 @@ is_a: GO:0042430 ! indole-containing compound metabolic process is_a: GO:0042445 ! hormone metabolic process is_a: GO:0043603 ! amide metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:16796 ! melatonin -relationship: has_primary_input_or_output CHEBI:16796 ! melatonin +intersection_of: has_primary_input_or_output CHEBI:16796 +relationship: has_primary_input_or_output CHEBI:16796 [Term] id: GO:0030187 @@ -74627,8 +62384,8 @@ is_a: GO:0042435 ! indole-containing compound biosynthetic process is_a: GO:0042446 ! hormone biosynthetic process is_a: GO:0043604 ! amide biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:16796 ! melatonin -relationship: has_primary_output CHEBI:16796 ! melatonin +intersection_of: has_primary_output CHEBI:16796 +relationship: has_primary_output CHEBI:16796 [Term] id: GO:0030193 @@ -74715,11 +62472,10 @@ namespace: biological_process def: "The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues." [GOC:mah, ISBN:0198506732] synonym: "heparan sulfate metabolic process" RELATED [] synonym: "heparin metabolism" EXACT [] -is_a: GO:0006790 ! sulfur compound metabolic process -is_a: GO:1903510 ! mucopolysaccharide metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:24505 ! heparins -relationship: has_primary_input_or_output CHEBI:24505 ! heparins +intersection_of: has_primary_input_or_output CHEBI:24505 +relationship: has_primary_input_or_output CHEBI:24505 [Term] id: GO:0030203 @@ -74727,10 +62483,10 @@ name: glycosaminoglycan metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glycosaminoglycans, any of a group of polysaccharides that contain amino sugars." [ISBN:0192800981] synonym: "glycosaminoglycan metabolism" EXACT [] -is_a: GO:0006022 ! aminoglycan metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:18085 ! glycosaminoglycan -relationship: has_primary_input_or_output CHEBI:18085 ! glycosaminoglycan +intersection_of: has_primary_input_or_output CHEBI:18085 +relationship: has_primary_input_or_output CHEBI:18085 [Term] id: GO:0030204 @@ -74740,11 +62496,10 @@ def: "The chemical reactions and pathways involving chondroitin sulfate, any mem synonym: "chondroitin sulfate metabolism" EXACT [] synonym: "chondroitin sulphate metabolic process" EXACT [] synonym: "chondroitin sulphate metabolism" EXACT [] -is_a: GO:0006790 ! sulfur compound metabolic process -is_a: GO:1903510 ! mucopolysaccharide metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:37397 ! chondroitin sulfate -relationship: has_primary_input_or_output CHEBI:37397 ! chondroitin sulfate +intersection_of: has_primary_input_or_output CHEBI:37397 +relationship: has_primary_input_or_output CHEBI:37397 relationship: part_of GO:0050654 ! chondroitin sulfate proteoglycan metabolic process [Term] @@ -74758,12 +62513,11 @@ synonym: "chondroitin sulfate formation" EXACT [] synonym: "chondroitin sulfate synthesis" EXACT [] synonym: "chondroitin sulphate biosynthesis" EXACT [] synonym: "chondroitin sulphate biosynthetic process" EXACT [] -is_a: GO:0006024 ! glycosaminoglycan biosynthetic process +is_a: GO:0009058 ! biosynthetic process is_a: GO:0030204 ! chondroitin sulfate metabolic process -is_a: GO:0044272 ! sulfur compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:37397 ! chondroitin sulfate -relationship: has_primary_output CHEBI:37397 ! chondroitin sulfate +intersection_of: has_primary_output CHEBI:37397 +relationship: has_primary_output CHEBI:37397 relationship: part_of GO:0050650 ! chondroitin sulfate proteoglycan biosynthetic process [Term] @@ -74776,12 +62530,11 @@ synonym: "chondroitin sulfate catabolism" EXACT [] synonym: "chondroitin sulfate degradation" EXACT [] synonym: "chondroitin sulphate catabolic process" EXACT [] synonym: "chondroitin sulphate catabolism" EXACT [] -is_a: GO:0006027 ! glycosaminoglycan catabolic process +is_a: GO:0009056 ! catabolic process is_a: GO:0030204 ! chondroitin sulfate metabolic process -is_a: GO:0044273 ! sulfur compound catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:37397 ! chondroitin sulfate -relationship: has_primary_input CHEBI:37397 ! chondroitin sulfate +intersection_of: has_primary_input CHEBI:37397 +relationship: has_primary_input CHEBI:37397 [Term] id: GO:0030210 @@ -74793,12 +62546,11 @@ synonym: "heparin anabolism" EXACT [] synonym: "heparin biosynthesis" EXACT [] synonym: "heparin formation" EXACT [] synonym: "heparin synthesis" EXACT [] -is_a: GO:0006024 ! glycosaminoglycan biosynthetic process +is_a: GO:0009058 ! biosynthetic process is_a: GO:0030202 ! heparin metabolic process -is_a: GO:0044272 ! sulfur compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:24505 ! heparins -relationship: has_primary_output CHEBI:24505 ! heparins +intersection_of: has_primary_output CHEBI:24505 +relationship: has_primary_output CHEBI:24505 [Term] id: GO:0030211 @@ -74809,12 +62561,11 @@ synonym: "heparan sulfate catabolic process" RELATED [] synonym: "heparin breakdown" EXACT [] synonym: "heparin catabolism" EXACT [] synonym: "heparin degradation" EXACT [] -is_a: GO:0006027 ! glycosaminoglycan catabolic process +is_a: GO:0009056 ! catabolic process is_a: GO:0030202 ! heparin metabolic process -is_a: GO:0044273 ! sulfur compound catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:24505 ! heparins -relationship: has_primary_input CHEBI:24505 ! heparins +intersection_of: has_primary_input CHEBI:24505 +relationship: has_primary_input CHEBI:24505 [Term] id: GO:0030212 @@ -74822,10 +62573,10 @@ name: hyaluronan metabolic process namespace: biological_process def: "The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." [GOC:mah, ISBN:0198506732] synonym: "hyaluronan metabolism" EXACT [] -is_a: GO:1903510 ! mucopolysaccharide metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:16336 ! hyaluronic acid -relationship: has_primary_input_or_output CHEBI:16336 ! hyaluronic acid +intersection_of: has_primary_input_or_output CHEBI:16336 +relationship: has_primary_input_or_output CHEBI:16336 [Term] id: GO:0030213 @@ -74836,11 +62587,11 @@ synonym: "hyaluronan anabolism" EXACT [] synonym: "hyaluronan biosynthesis" EXACT [] synonym: "hyaluronan formation" EXACT [] synonym: "hyaluronan synthesis" EXACT [] -is_a: GO:0006024 ! glycosaminoglycan biosynthetic process +is_a: GO:0009058 ! biosynthetic process is_a: GO:0030212 ! hyaluronan metabolic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:16336 ! hyaluronic acid -relationship: has_primary_output CHEBI:16336 ! hyaluronic acid +intersection_of: has_primary_output CHEBI:16336 +relationship: has_primary_output CHEBI:16336 [Term] id: GO:0030214 @@ -74850,11 +62601,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of hyaluron synonym: "hyaluronan breakdown" EXACT [] synonym: "hyaluronan catabolism" EXACT [] synonym: "hyaluronan degradation" EXACT [] -is_a: GO:0006027 ! glycosaminoglycan catabolic process +is_a: GO:0009056 ! catabolic process is_a: GO:0030212 ! hyaluronan metabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:16336 ! hyaluronic acid -relationship: has_primary_input CHEBI:16336 ! hyaluronic acid +intersection_of: has_primary_input CHEBI:16336 +relationship: has_primary_input CHEBI:16336 [Term] id: GO:0030216 @@ -74988,17 +62739,6 @@ intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000235 ! macrophage relationship: results_in_acquisition_of_features_of CL:0000235 ! macrophage -[Term] -id: GO:0030226 -name: apolipoprotein receptor activity -namespace: molecular_function -def: "Combining with an apolipoprotein to initiate a change in cell activity." [GOC:mah, ISBN:0198506732] -is_a: GO:0038024 ! cargo receptor activity -intersection_of: GO:0038024 ! cargo receptor activity -intersection_of: has_input CHEBI:39015 ! apolipoprotein -relationship: has_input CHEBI:39015 ! apolipoprotein -relationship: has_part GO:0034185 ! apolipoprotein binding - [Term] id: GO:0030228 name: lipoprotein particle receptor activity @@ -75009,8 +62749,8 @@ synonym: "lipoprotein receptor activity" EXACT [GOC:dph] synonym: "plasma lipoprotein particle receptor activity" NARROW [GOC:BHF] is_a: GO:0038024 ! cargo receptor activity intersection_of: GO:0038024 ! cargo receptor activity -intersection_of: has_input CHEBI:6495 ! lipoprotein -relationship: has_input CHEBI:6495 ! lipoprotein +intersection_of: has_input CHEBI:6495 +relationship: has_input CHEBI:6495 relationship: has_part GO:0071813 ! lipoprotein particle binding [Term] @@ -75033,8 +62773,8 @@ synonym: "enzyme modulator" EXACT [] synonym: "metalloenzyme regulator activity" NARROW [] is_a: GO:0098772 ! molecular function regulator activity intersection_of: GO:0098772 ! molecular function regulator activity -intersection_of: regulates GO:0003824 ! catalytic activity -relationship: regulates GO:0003824 ! catalytic activity +intersection_of: directly_regulates GO:0003824 ! catalytic activity +relationship: directly_regulates GO:0003824 ! catalytic activity [Term] id: GO:0030239 @@ -75067,8 +62807,8 @@ synonym: "selectin" RELATED [] synonym: "sugar binding" EXACT [] is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:16646 ! carbohydrate -relationship: has_input CHEBI:16646 ! carbohydrate +intersection_of: has_input CHEBI:16646 +relationship: has_input CHEBI:16646 [Term] id: GO:0030247 @@ -75077,10 +62817,10 @@ namespace: molecular_function alt_id: GO:0002506 def: "Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:mah] synonym: "polysaccharide assembly with MHC class II protein complex" NARROW [] -is_a: GO:0030246 ! carbohydrate binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:18154 ! polysaccharide -relationship: has_input CHEBI:18154 ! polysaccharide +intersection_of: has_input CHEBI:18154 +relationship: has_input CHEBI:18154 [Term] id: GO:0030252 @@ -75178,10 +62918,10 @@ id: GO:0030291 name: protein serine/threonine kinase inhibitor activity namespace: molecular_function def: "Binds to and stops, prevents or reduces the activity of a protein serine/threonine kinase." [GOC:mah] -is_a: GO:0003674 ! molecular_function -intersection_of: GO:0003674 ! molecular_function -intersection_of: negatively_regulates GO:0004674 ! protein serine/threonine kinase activity -relationship: negatively_regulates GO:0004674 ! protein serine/threonine kinase activity +is_a: GO:0004860 ! protein kinase inhibitor activity +intersection_of: GO:0098772 ! molecular function regulator activity +intersection_of: directly_negatively_regulates GO:0004674 ! protein serine/threonine kinase activity +relationship: directly_negatively_regulates GO:0004674 ! protein serine/threonine kinase activity [Term] id: GO:0030292 @@ -75715,10 +63455,10 @@ synonym: "bile acid degradation" EXACT [] synonym: "cholate catabolic process" NARROW [] xref: MetaCyc:7ALPHADEHYDROX-PWY is_a: GO:0008206 ! bile acid metabolic process -is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:36235 ! bile acid anion -relationship: has_primary_input CHEBI:36235 ! bile acid anion +intersection_of: has_primary_input CHEBI:36235 +relationship: has_primary_input CHEBI:36235 [Term] id: GO:0030574 @@ -75765,44 +63505,6 @@ is_a: GO:0060326 ! cell chemotaxis intersection_of: GO:0006935 ! chemotaxis intersection_of: results_in_movement_of CL:0000738 ! leukocyte -[Term] -id: GO:0030642 -name: intracellular sulfate ion homeostasis -namespace: biological_process -def: "A homeostatic process involved in the maintenance of a steady state level of sulfate ions within a cell." [GOC:mah] -synonym: "cellular sulfate ion homeostasis" EXACT [] -synonym: "sulphate ion homeostasis" BROAD [] -is_a: GO:0055063 ! sulfate ion homeostasis -is_a: GO:0055082 ! intracellular chemical homeostasis -intersection_of: GO:0055082 ! intracellular chemical homeostasis -intersection_of: regulates_levels_of CHEBI:16189 ! sulfate - -[Term] -id: GO:0030643 -name: intracellular phosphate ion homeostasis -namespace: biological_process -def: "A homeostatic process involved in the maintenance of a steady state level of phosphate ions within a cell." [GOC:mah] -synonym: "cellular phosphate ion homeostasis" EXACT [] -is_a: GO:0055062 ! phosphate ion homeostasis -is_a: GO:0055082 ! intracellular chemical homeostasis -intersection_of: GO:0019725 ! cellular homeostasis -intersection_of: regulates_levels_of CHEBI:35780 ! phosphate ion - -[Term] -id: GO:0030645 -name: glucose catabolic process to butyrate -namespace: biological_process -def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glucose, with the production of acetic acid, butyric acid, carbon dioxide (CO2), and dihydrogen; effected by some saccharolytic species of Clostridium, e.g. C. butyricum." [ISBN:0198506732] -synonym: "butyrate fermentation" EXACT [] -synonym: "glucose fermentation to butyrate" EXACT [] -is_a: GO:0006007 ! glucose catabolic process -is_a: GO:0006113 ! fermentation -is_a: GO:0019605 ! butyrate metabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:17234 ! glucose -intersection_of: has_primary_output CHEBI:17968 ! butyrate -relationship: has_primary_output CHEBI:17968 ! butyrate - [Term] id: GO:0030658 name: transport vesicle membrane @@ -77160,6 +64862,7 @@ namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." [GOC:mah, GOC:tb] subset: goslim_yeast is_a: GO:0051246 ! regulation of protein metabolic process +is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0036211 ! protein modification process relationship: regulates GO:0036211 ! protein modification process @@ -77173,6 +64876,7 @@ synonym: "down regulation of protein modification" EXACT [] synonym: "down-regulation of protein modification" EXACT [] synonym: "downregulation of protein modification" EXACT [] synonym: "inhibition of protein modification" NARROW [] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0031399 ! regulation of protein modification process is_a: GO:0051248 ! negative regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation @@ -77189,33 +64893,23 @@ synonym: "stimulation of protein modification" NARROW [] synonym: "up regulation of protein modification" EXACT [] synonym: "up-regulation of protein modification" EXACT [] synonym: "upregulation of protein modification" EXACT [] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0031399 ! regulation of protein modification process is_a: GO:0051247 ! positive regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0036211 ! protein modification process relationship: positively_regulates GO:0036211 ! protein modification process -[Term] -id: GO:0031402 -name: sodium ion binding -namespace: molecular_function -def: "Binding to a sodium ion (Na+)." [GOC:mah] -synonym: "Na+ ion binding" EXACT [] -is_a: GO:0031420 ! alkali metal ion binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:29101 ! sodium(1+) -relationship: has_input CHEBI:29101 ! sodium(1+) - [Term] id: GO:0031406 name: carboxylic acid binding namespace: molecular_function def: "Binding to a carboxylic acid, an organic acid containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:mah, ISBN:0198506732] subset: goslim_pir -is_a: GO:0043168 ! anion binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:29067 ! carboxylic acid anion -relationship: has_input CHEBI:29067 ! carboxylic acid anion +intersection_of: has_input CHEBI:29067 +relationship: has_input CHEBI:29067 [Term] id: GO:0031410 @@ -77238,16 +64932,6 @@ intersection_of: GO:0031982 ! vesicle intersection_of: part_of GO:0005737 ! cytoplasm relationship: part_of GO:0005737 ! cytoplasm -[Term] -id: GO:0031420 -name: alkali metal ion binding -namespace: molecular_function -def: "Binding to an alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen." [GOC:mah] -is_a: GO:0046872 ! metal ion binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:33504 ! alkali metal cation -relationship: has_input CHEBI:33504 ! alkali metal cation - [Term] id: GO:0031424 name: keratinization @@ -77613,7 +65297,6 @@ namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids." [GOC:mah] is_a: GO:0031329 ! regulation of cellular catabolic process is_a: GO:0031943 ! regulation of glucocorticoid metabolic process -is_a: GO:0050994 ! regulation of lipid catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006713 ! glucocorticoid catabolic process relationship: regulates GO:0006713 ! glucocorticoid catabolic process @@ -77630,7 +65313,6 @@ synonym: "inhibition of glucocorticoid catabolic process" NARROW [] is_a: GO:0031330 ! negative regulation of cellular catabolic process is_a: GO:0031944 ! negative regulation of glucocorticoid metabolic process is_a: GO:0031949 ! regulation of glucocorticoid catabolic process -is_a: GO:0050995 ! negative regulation of lipid catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006713 ! glucocorticoid catabolic process relationship: negatively_regulates GO:0006713 ! glucocorticoid catabolic process @@ -77648,7 +65330,6 @@ synonym: "upregulation of glucocorticoid catabolic process" EXACT [] is_a: GO:0031331 ! positive regulation of cellular catabolic process is_a: GO:0031945 ! positive regulation of glucocorticoid metabolic process is_a: GO:0031949 ! regulation of glucocorticoid catabolic process -is_a: GO:0050996 ! positive regulation of lipid catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006713 ! glucocorticoid catabolic process relationship: positively_regulates GO:0006713 ! glucocorticoid catabolic process @@ -77661,17 +65342,6 @@ def: "The series of molecular signals initiated by corticosteroid binding to its synonym: "corticosteroid receptor signalling pathway" EXACT [] is_a: GO:0030518 ! intracellular steroid hormone receptor signaling pathway -[Term] -id: GO:0031960 -name: response to corticosteroid -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids." [GOC:mah, PMID:11027914] -synonym: "response to corticosteroid stimulus" EXACT [GOC:dos] -is_a: GO:0048545 ! response to steroid hormone -intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:50858 ! corticosteroid -relationship: has_input CHEBI:50858 ! corticosteroid - [Term] id: GO:0031965 name: nuclear membrane @@ -77775,41 +65445,10 @@ id: GO:0032052 name: bile acid binding namespace: molecular_function def: "Binding to a bile acid, a steroid carboxylic acids occurring in bile." [GOC:rph] -is_a: GO:0033293 ! monocarboxylic acid binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:36235 ! bile acid anion -relationship: has_input CHEBI:36235 ! bile acid anion - -[Term] -id: GO:0032055 -name: negative regulation of translation in response to stress -namespace: biological_process -def: "Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress." [GOC:mah] -synonym: "down regulation of translation in response to stress" EXACT [] -synonym: "down-regulation of translation in response to stress" EXACT [] -synonym: "downregulation of translation in response to stress" EXACT [] -synonym: "inhibition of translation in response to stress" NARROW [] -is_a: GO:0017148 ! negative regulation of translation -is_a: GO:0043555 ! regulation of translation in response to stress -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0006412 ! translation -intersection_of: part_of GO:0033554 ! cellular response to stress - -[Term] -id: GO:0032056 -name: positive regulation of translation in response to stress -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress." [GOC:mah] -synonym: "activation of translation in response to stress" NARROW [] -synonym: "stimulation of translation in response to stress" NARROW [] -synonym: "up regulation of translation in response to stress" EXACT [] -synonym: "up-regulation of translation in response to stress" EXACT [] -synonym: "upregulation of translation in response to stress" EXACT [] -is_a: GO:0043555 ! regulation of translation in response to stress -is_a: GO:0045727 ! positive regulation of translation -intersection_of: GO:0065007 ! biological regulation -intersection_of: part_of GO:0033554 ! cellular response to stress -intersection_of: positively_regulates GO:0006412 ! translation +intersection_of: has_input CHEBI:36235 +relationship: has_input CHEBI:36235 [Term] id: GO:0032057 @@ -77889,8 +65528,8 @@ synonym: "DNase regulator" RELATED [] is_a: GO:0032069 ! regulation of nuclease activity is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0004536 ! deoxyribonuclease activity -relationship: regulates GO:0004536 ! deoxyribonuclease activity +intersection_of: regulates GO:0004536 ! DNA nuclease activity +relationship: regulates GO:0004536 ! DNA nuclease activity [Term] id: GO:0032074 @@ -77942,8 +65581,8 @@ is_a: GO:0032070 ! regulation of deoxyribonuclease activity is_a: GO:0032074 ! negative regulation of nuclease activity is_a: GO:0051053 ! negative regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0004536 ! deoxyribonuclease activity -relationship: negatively_regulates GO:0004536 ! deoxyribonuclease activity +intersection_of: negatively_regulates GO:0004536 ! DNA nuclease activity +relationship: negatively_regulates GO:0004536 ! DNA nuclease activity [Term] id: GO:0032077 @@ -77961,8 +65600,8 @@ is_a: GO:0032070 ! regulation of deoxyribonuclease activity is_a: GO:0032075 ! positive regulation of nuclease activity is_a: GO:0051054 ! positive regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0004536 ! deoxyribonuclease activity -relationship: positively_regulates GO:0004536 ! deoxyribonuclease activity +intersection_of: positively_regulates GO:0004536 ! DNA nuclease activity +relationship: positively_regulates GO:0004536 ! DNA nuclease activity [Term] id: GO:0032091 @@ -78488,12 +66127,11 @@ synonym: "aldosterone metabolism" EXACT [] is_a: GO:0006081 ! cellular aldehyde metabolic process is_a: GO:0008207 ! C21-steroid hormone metabolic process is_a: GO:0008212 ! mineralocorticoid metabolic process -is_a: GO:0034308 ! primary alcohol metabolic process is_a: GO:0042180 ! cellular ketone metabolic process -is_a: GO:0120254 ! olefinic compound metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:27584 ! aldosterone -relationship: has_primary_input_or_output CHEBI:27584 ! aldosterone +intersection_of: has_primary_input_or_output CHEBI:27584 +relationship: has_primary_input_or_output CHEBI:27584 [Term] id: GO:0032342 @@ -78503,29 +66141,23 @@ def: "The chemical reactions and pathways resulting in the formation of aldoster is_a: GO:0006700 ! C21-steroid hormone biosynthetic process is_a: GO:0006705 ! mineralocorticoid biosynthetic process is_a: GO:0032341 ! aldosterone metabolic process -is_a: GO:0034309 ! primary alcohol biosynthetic process is_a: GO:0042181 ! ketone biosynthetic process is_a: GO:0046184 ! aldehyde biosynthetic process -is_a: GO:0120255 ! olefinic compound biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:27584 ! aldosterone -relationship: has_primary_output CHEBI:27584 ! aldosterone +intersection_of: has_primary_output CHEBI:27584 +relationship: has_primary_output CHEBI:27584 [Term] id: GO:0032343 name: aldosterone catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance." [PMID:16527843] -is_a: GO:0006712 ! mineralocorticoid catabolic process -is_a: GO:0008208 ! C21-steroid hormone catabolic process +is_a: GO:0009056 ! catabolic process is_a: GO:0032341 ! aldosterone metabolic process -is_a: GO:0034310 ! primary alcohol catabolic process -is_a: GO:0042182 ! ketone catabolic process -is_a: GO:0046185 ! aldehyde catabolic process -is_a: GO:0120256 ! olefinic compound catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:27584 ! aldosterone -relationship: has_primary_input CHEBI:27584 ! aldosterone +intersection_of: has_primary_input CHEBI:27584 +relationship: has_primary_input CHEBI:27584 [Term] id: GO:0032344 @@ -78587,7 +66219,6 @@ def: "Any process that modulates the frequency, rate or extent of the chemical r is_a: GO:0010566 ! regulation of ketone biosynthetic process is_a: GO:0032344 ! regulation of aldosterone metabolic process is_a: GO:0090030 ! regulation of steroid hormone biosynthetic process -is_a: GO:1902930 ! regulation of alcohol biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032342 ! aldosterone biosynthetic process relationship: regulates GO:0032342 ! aldosterone biosynthetic process @@ -78604,7 +66235,6 @@ synonym: "inhibition of aldosterone biosynthetic process" NARROW [] is_a: GO:0032345 ! negative regulation of aldosterone metabolic process is_a: GO:0032347 ! regulation of aldosterone biosynthetic process is_a: GO:0090032 ! negative regulation of steroid hormone biosynthetic process -is_a: GO:1902931 ! negative regulation of alcohol biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032342 ! aldosterone biosynthetic process relationship: negatively_regulates GO:0032342 ! aldosterone biosynthetic process @@ -78622,7 +66252,6 @@ synonym: "upregulation of aldosterone biosynthetic process" EXACT [] is_a: GO:0032346 ! positive regulation of aldosterone metabolic process is_a: GO:0032347 ! regulation of aldosterone biosynthetic process is_a: GO:0090031 ! positive regulation of steroid hormone biosynthetic process -is_a: GO:1902932 ! positive regulation of alcohol biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032342 ! aldosterone biosynthetic process relationship: positively_regulates GO:0032342 ! aldosterone biosynthetic process @@ -78695,12 +66324,10 @@ namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen." [GOC:mah, ISBN:0911910123] synonym: "response to E2 stimulus" EXACT [] synonym: "response to estradiol stimulus" EXACT [GOC:dos] -is_a: GO:0014070 ! response to organic cyclic compound -is_a: GO:0033993 ! response to lipid -is_a: GO:1901700 ! response to oxygen-containing compound +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:23965 ! estradiol -relationship: has_input CHEBI:23965 ! estradiol +intersection_of: has_input CHEBI:23965 +relationship: has_input CHEBI:23965 [Term] id: GO:0032364 @@ -78711,8 +66338,8 @@ synonym: "cellular oxygen homeostasis" EXACT [] synonym: "oxygen homeostasis" BROAD [] is_a: GO:0055082 ! intracellular chemical homeostasis intersection_of: GO:0055082 ! intracellular chemical homeostasis -intersection_of: regulates_levels_of CHEBI:15379 ! dioxygen -relationship: regulates_levels_of CHEBI:15379 ! dioxygen +intersection_of: regulates_levels_of CHEBI:15379 +relationship: regulates_levels_of CHEBI:15379 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24224" xsd:anyURI [Term] @@ -78723,7 +66350,7 @@ def: "The directed movement of lipids within cells." [GOC:mah] is_a: GO:0006869 ! lipid transport is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:18059 ! lipid +intersection_of: has_primary_input CHEBI:18059 intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure [Term] @@ -79037,6 +66664,8 @@ synonym: "Golgi calcium ion concentration regulation" EXACT [] synonym: "regulation of calcium ion concentration in Golgi" EXACT [] synonym: "regulation of Golgi calcium ion concentration" EXACT [] is_a: GO:0006874 ! intracellular calcium ion homeostasis +is_a: GO:0055074 ! calcium ion homeostasis +is_a: GO:0055082 ! intracellular chemical homeostasis intersection_of: GO:0055074 ! calcium ion homeostasis intersection_of: occurs_in GO:0005794 ! Golgi apparatus relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota @@ -79051,7 +66680,7 @@ def: "The directed movement of calcium ions (Ca2+) into, out of or within the Go synonym: "Golgi calcium transport" EXACT [] is_a: GO:0006816 ! calcium ion transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:29108 ! calcium(2+) +intersection_of: has_primary_input CHEBI:29108 intersection_of: results_in_transport_to_from_or_in GO:0005794 ! Golgi apparatus relationship: results_in_transport_to_from_or_in GO:0005794 ! Golgi apparatus @@ -79217,11 +66846,10 @@ name: response to progesterone namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus." [GOC:sl] synonym: "response to progesterone stimulus" EXACT [GOC:dos] -is_a: GO:0048545 ! response to steroid hormone -is_a: GO:1901654 ! response to ketone +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:17026 ! progesterone -relationship: has_input CHEBI:17026 ! progesterone +intersection_of: has_input CHEBI:17026 +relationship: has_input CHEBI:17026 [Term] id: GO:0032589 @@ -80337,6 +67965,7 @@ namespace: biological_process alt_id: GO:0062103 def: "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication." [GOC:mah, GOC:txnOH] comment: Note that, in some cases, viral RNA replication and viral transcription from RNA actually refer to the same process, but may be called differently depending on the focus of a specific research study. +subset: gocheck_do_not_annotate synonym: "double-stranded RNA biosynthesis" NARROW [] synonym: "double-stranded RNA biosynthetic process" NARROW [] synonym: "dsRNA biosynthesis" NARROW [] @@ -80345,12 +67974,11 @@ synonym: "RNA anabolism" EXACT [] synonym: "RNA biosynthesis" EXACT [] synonym: "RNA formation" EXACT [] synonym: "RNA synthesis" EXACT [] -is_a: GO:0009059 ! macromolecule biosynthetic process +is_a: GO:0009058 ! biosynthetic process is_a: GO:0016070 ! RNA metabolic process -is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:33697 ! ribonucleic acid -relationship: has_primary_output CHEBI:33697 ! ribonucleic acid +intersection_of: has_primary_output CHEBI:33697 +relationship: has_primary_output CHEBI:33697 [Term] id: GO:0032780 @@ -80394,11 +68022,10 @@ id: GO:0032782 name: bile acid secretion namespace: biological_process def: "The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue." [GOC:ecd] -is_a: GO:0015718 ! monocarboxylic acid transport is_a: GO:0046717 ! acid secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:36235 ! bile acid anion -relationship: has_primary_input CHEBI:36235 ! bile acid anion +intersection_of: has_primary_input CHEBI:36235 +relationship: has_primary_input CHEBI:36235 [Term] id: GO:0032787 @@ -80410,8 +68037,8 @@ synonym: "monocarboxylate metabolic process" EXACT [] synonym: "monocarboxylic acid metabolism" EXACT [] is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:35757 ! monocarboxylic acid anion -relationship: has_primary_input_or_output CHEBI:35757 ! monocarboxylic acid anion +intersection_of: has_primary_input_or_output CHEBI:35757 +relationship: has_primary_input_or_output CHEBI:35757 [Term] id: GO:0032790 @@ -80447,7 +68074,7 @@ synonym: "downregulation of epinephrine secretion" EXACT [] synonym: "inhibition of epinephrine secretion" NARROW [] synonym: "negative regulation of adrenaline secretion" EXACT [] is_a: GO:0014060 ! regulation of epinephrine secretion -is_a: GO:0033604 ! negative regulation of catecholamine secretion +is_a: GO:0051048 ! negative regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048242 ! epinephrine secretion relationship: negatively_regulates GO:0048242 ! epinephrine secretion @@ -80464,7 +68091,7 @@ synonym: "up regulation of epinephrine secretion" EXACT [] synonym: "up-regulation of epinephrine secretion" EXACT [] synonym: "upregulation of epinephrine secretion" EXACT [] is_a: GO:0014060 ! regulation of epinephrine secretion -is_a: GO:0033605 ! positive regulation of catecholamine secretion +is_a: GO:0051047 ! positive regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048242 ! epinephrine secretion relationship: positively_regulates GO:0048242 ! epinephrine secretion @@ -80900,8 +68527,8 @@ namespace: molecular_function def: "Binding to calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid." [GOC:ecd] is_a: GO:0097644 ! calcitonin family binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:3306 ! calcitonin -relationship: has_input CHEBI:3306 ! calcitonin +intersection_of: has_input CHEBI:3306 +relationship: has_input CHEBI:3306 [Term] id: GO:0032868 @@ -81076,8 +68703,8 @@ synonym: "down-regulation of superoxide release" EXACT [] synonym: "downregulation of superoxide release" EXACT [] synonym: "inhibition of superoxide release" NARROW [] synonym: "negative regulation of superoxide release" EXACT [GOC:dph, GOC:tb] +is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0032928 ! regulation of superoxide anion generation -is_a: GO:2000378 ! negative regulation of reactive oxygen species metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042554 ! superoxide anion generation relationship: negatively_regulates GO:0042554 ! superoxide anion generation @@ -81093,40 +68720,12 @@ synonym: "stimulation of superoxide release" NARROW [] synonym: "up regulation of superoxide release" EXACT [] synonym: "up-regulation of superoxide release" EXACT [] synonym: "upregulation of superoxide release" EXACT [] +is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0032928 ! regulation of superoxide anion generation -is_a: GO:2000379 ! positive regulation of reactive oxygen species metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042554 ! superoxide anion generation relationship: positively_regulates GO:0042554 ! superoxide anion generation -[Term] -id: GO:0032938 -name: negative regulation of translation in response to oxidative stress -namespace: biological_process -def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:mah] -is_a: GO:0032057 ! negative regulation of translational initiation in response to stress -is_a: GO:0043556 ! regulation of translation in response to oxidative stress -is_a: GO:0043558 ! regulation of translational initiation in response to stress -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0006413 ! translational initiation -intersection_of: part_of GO:0034599 ! cellular response to oxidative stress - -[Term] -id: GO:0032939 -name: positive regulation of translation in response to oxidative stress -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:mah] -synonym: "activation of translation in response to oxidative stress" NARROW [] -synonym: "stimulation of translation in response to oxidative stress" NARROW [] -synonym: "up regulation of translation in response to oxidative stress" EXACT [] -synonym: "up-regulation of translation in response to oxidative stress" EXACT [] -synonym: "upregulation of translation in response to oxidative stress" EXACT [] -is_a: GO:0032056 ! positive regulation of translation in response to stress -intersection_of: GO:0065007 ! biological regulation -intersection_of: part_of GO:0034599 ! cellular response to oxidative stress -intersection_of: positively_regulates GO:0006412 ! translation -relationship: part_of GO:0034599 ! cellular response to oxidative stress - [Term] id: GO:0032940 name: secretion by cell @@ -81405,7 +69004,7 @@ namespace: cellular_component def: "A macromolecular complex containing separate protein and lipid molecules. Separate in this context means not covalently bound to each other." [GOC:mah] comment: Macromolecular complexes in which the lipid component is all covalently bound to protein are not considered protein-lipid complexes. is_a: GO:0032991 ! protein-containing complex -relationship: has_part CHEBI:18059 ! lipid +relationship: has_part CHEBI:18059 [Term] id: GO:0032997 @@ -81511,59 +69110,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002279 ! mast cell activation involved in immune response relationship: positively_regulates GO:0002279 ! mast cell activation involved in immune response -[Term] -id: GO:0033013 -name: tetrapyrrole metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] -subset: goslim_pombe -subset: prokaryote_subset -synonym: "tetrapyrrole metabolism" EXACT [] -is_a: GO:0006725 ! cellular aromatic compound metabolic process -is_a: GO:0046483 ! heterocycle metabolic process -is_a: GO:1901360 ! organic cyclic compound metabolic process -is_a: GO:1901564 ! organonitrogen compound metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:26932 ! tetrapyrrole -relationship: has_primary_input_or_output CHEBI:26932 ! tetrapyrrole - -[Term] -id: GO:0033014 -name: tetrapyrrole biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] -synonym: "tetrapyrrole anabolism" EXACT [] -synonym: "tetrapyrrole biosynthesis" EXACT [] -synonym: "tetrapyrrole formation" EXACT [] -synonym: "tetrapyrrole synthesis" EXACT [] -is_a: GO:0018130 ! heterocycle biosynthetic process -is_a: GO:0019438 ! aromatic compound biosynthetic process -is_a: GO:0033013 ! tetrapyrrole metabolic process -is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process -is_a: GO:1901362 ! organic cyclic compound biosynthetic process -is_a: GO:1901566 ! organonitrogen compound biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:26932 ! tetrapyrrole -relationship: has_primary_output CHEBI:26932 ! tetrapyrrole - -[Term] -id: GO:0033015 -name: tetrapyrrole catabolic process -namespace: biological_process -def: "The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] -synonym: "tetrapyrrole breakdown" EXACT [] -synonym: "tetrapyrrole catabolism" EXACT [] -synonym: "tetrapyrrole degradation" EXACT [] -is_a: GO:0019439 ! aromatic compound catabolic process -is_a: GO:0033013 ! tetrapyrrole metabolic process -is_a: GO:0044270 ! cellular nitrogen compound catabolic process -is_a: GO:0046700 ! heterocycle catabolic process -is_a: GO:1901361 ! organic cyclic compound catabolic process -is_a: GO:1901565 ! organonitrogen compound catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:26932 ! tetrapyrrole -relationship: has_primary_input CHEBI:26932 ! tetrapyrrole - [Term] id: GO:0033023 name: mast cell homeostasis @@ -81762,8 +69308,8 @@ def: "Any process in which a polysaccharide is transported to, or maintained in, synonym: "polysaccharide localisation" EXACT [GOC:mah] is_a: GO:0033036 ! macromolecule localization intersection_of: GO:0033036 ! macromolecule localization -intersection_of: has_primary_input CHEBI:18154 ! polysaccharide -relationship: has_primary_input CHEBI:18154 ! polysaccharide +intersection_of: has_primary_input CHEBI:18154 +relationship: has_primary_input CHEBI:18154 [Term] id: GO:0033043 @@ -82103,11 +69649,12 @@ synonym: "iron assimilation" RELATED [] is_a: GO:0006826 ! iron ion transport is_a: GO:0006879 ! intracellular iron ion homeostasis is_a: GO:0051649 ! establishment of localization in cell -is_a: GO:0098657 ! import into cell intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:24875 ! iron cation +intersection_of: has_primary_input CHEBI:24875 intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure intersection_of: has_target_start_location GO:0005576 ! extracellular region +relationship: has_target_end_location GO:0005622 ! intracellular anatomical structure +relationship: has_target_start_location GO:0005576 ! extracellular region created_by: mah creation_date: 2009-05-01T04:19:14Z @@ -82119,8 +69666,8 @@ def: "Binding to an amide, any derivative of an oxoacid in which an acidic hydro subset: goslim_pir is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:32988 ! amide -relationship: has_input CHEBI:32988 ! amide +intersection_of: has_input CHEBI:32988 +relationship: has_input CHEBI:32988 [Term] id: GO:0033238 @@ -82129,7 +69676,7 @@ namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines." [GOC:mah] synonym: "regulation of amine metabolism" EXACT [] synonym: "regulation of cellular amine metabolic process" EXACT [] -is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009308 ! amine metabolic process relationship: regulates GO:0009308 ! amine metabolic process @@ -82141,8 +69688,8 @@ namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines." [GOC:mah] synonym: "negative regulation of amine metabolism" EXACT [] synonym: "negative regulation of cellular amine metabolic process" EXACT [] +is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0033238 ! regulation of amine metabolic process -is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009308 ! amine metabolic process relationship: negatively_regulates GO:0009308 ! amine metabolic process @@ -82154,8 +69701,8 @@ namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines." [GOC:mah] synonym: "positive regulation of amine metabolism" EXACT [] synonym: "positive regulation of cellular amine metabolic process" EXACT [] +is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0033238 ! regulation of amine metabolic process -is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009308 ! amine metabolic process relationship: positively_regulates GO:0009308 ! amine metabolic process @@ -82224,10 +69771,10 @@ id: GO:0033293 name: monocarboxylic acid binding namespace: molecular_function def: "Binding to a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-)." [GOC:mah] -is_a: GO:0031406 ! carboxylic acid binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:35757 ! monocarboxylic acid anion -relationship: has_input CHEBI:35757 ! monocarboxylic acid anion +intersection_of: has_input CHEBI:35757 +relationship: has_input CHEBI:35757 [Term] id: GO:0033326 @@ -82406,8 +69953,8 @@ synonym: "nitric oxide homeostasis" BROAD [] synonym: "NO homeostasis" BROAD [] is_a: GO:0055082 ! intracellular chemical homeostasis intersection_of: GO:0055082 ! intracellular chemical homeostasis -intersection_of: regulates_levels_of CHEBI:16480 ! nitric oxide -relationship: regulates_levels_of CHEBI:16480 ! nitric oxide +intersection_of: regulates_levels_of CHEBI:16480 +relationship: regulates_levels_of CHEBI:16480 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24224" xsd:anyURI [Term] @@ -82417,50 +69964,8 @@ namespace: biological_process def: "A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell." [GOC:mah] is_a: GO:0048878 ! chemical homeostasis intersection_of: GO:0048878 ! chemical homeostasis -intersection_of: regulates_levels_of CHEBI:16646 ! carbohydrate -relationship: regulates_levels_of CHEBI:16646 ! carbohydrate - -[Term] -id: GO:0033508 -name: glutamate catabolic process to butyrate -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including butyrate." [GOC:mah, MetaCyc:PWY-5087] -synonym: "glutamate breakdown to butyrate" EXACT [] -synonym: "glutamate degradation to butyrate" EXACT [] -xref: MetaCyc:PWY-5087 -is_a: GO:0006538 ! glutamate catabolic process -is_a: GO:0019605 ! butyrate metabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:14321 ! glutamate(1-) -intersection_of: has_primary_output CHEBI:17968 ! butyrate -relationship: has_primary_output CHEBI:17968 ! butyrate - -[Term] -id: GO:0033526 -name: tetrapyrrole biosynthetic process from glutamate -namespace: biological_process -def: "The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate." [GOC:mah, MetaCyc:PWY-5188] -synonym: "tetrapyrrole anabolism from glutamate" EXACT [] -synonym: "tetrapyrrole biosynthesis from glutamate" EXACT [] -synonym: "tetrapyrrole formation from glutamate" EXACT [] -synonym: "tetrapyrrole synthesis from glutamate" EXACT [] -xref: MetaCyc:PWY-5188 -is_a: GO:0006536 ! glutamate metabolic process -is_a: GO:0033014 ! tetrapyrrole biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_input CHEBI:14321 ! glutamate(1-) -intersection_of: has_primary_output CHEBI:26932 ! tetrapyrrole -relationship: has_primary_input CHEBI:14321 ! glutamate(1-) - -[Term] -id: GO:0033554 -name: cellular response to stress -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:mah] -comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. -subset: gocheck_do_not_manually_annotate -is_a: GO:0006950 ! response to stress -is_a: GO:0051716 ! cellular response to stimulus +intersection_of: regulates_levels_of CHEBI:16646 +relationship: regulates_levels_of CHEBI:16646 [Term] id: GO:0033568 @@ -82500,12 +70005,10 @@ name: response to testosterone namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus." [GOC:sl] synonym: "response to testosterone stimulus" EXACT [GOC:dos] -is_a: GO:0014070 ! response to organic cyclic compound -is_a: GO:0033993 ! response to lipid -is_a: GO:1901654 ! response to ketone +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:17347 ! testosterone -relationship: has_input CHEBI:17347 ! testosterone +intersection_of: has_input CHEBI:17347 +relationship: has_input CHEBI:17347 [Term] id: GO:0033602 @@ -82697,22 +70200,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0033687 ! osteoblast proliferation relationship: positively_regulates GO:0033687 ! osteoblast proliferation -[Term] -id: GO:0033692 -name: cellular polysaccharide biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, occurring at the level of an individual cell." [GOC:go_curators] -synonym: "cellular glycan biosynthesis" EXACT [] -synonym: "cellular glycan biosynthetic process" EXACT [] -synonym: "cellular polysaccharide anabolism" EXACT [] -synonym: "cellular polysaccharide biosynthesis" EXACT [] -synonym: "cellular polysaccharide formation" EXACT [] -synonym: "cellular polysaccharide synthesis" EXACT [] -is_a: GO:0000271 ! polysaccharide biosynthetic process -is_a: GO:0034637 ! cellular carbohydrate biosynthetic process -is_a: GO:0034645 ! cellular macromolecule biosynthetic process -is_a: GO:0044264 ! cellular polysaccharide metabolic process - [Term] id: GO:0033750 name: ribosome localization @@ -82733,20 +70220,20 @@ name: response to glucagon namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus." [GOC:sl] synonym: "response to glucagon stimulus" EXACT [GOC:dos] -is_a: GO:0043434 ! response to peptide hormone +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:5391 ! glucagon -relationship: has_input CHEBI:5391 ! glucagon +intersection_of: has_input CHEBI:5391 +relationship: has_input CHEBI:5391 [Term] id: GO:0033993 name: response to lipid namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus." [GOC:sl] -is_a: GO:0010033 ! response to organic substance +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:18059 ! lipid -relationship: has_input CHEBI:18059 ! lipid +intersection_of: has_input CHEBI:18059 +relationship: has_input CHEBI:18059 [Term] id: GO:0034067 @@ -82877,17 +70364,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0034102 ! erythrocyte clearance relationship: positively_regulates GO:0034102 ! erythrocyte clearance -[Term] -id: GO:0034185 -name: apolipoprotein binding -namespace: molecular_function -def: "Binding to an apolipoprotein, the protein component of a lipoprotein complex." [GOC:BHF, GOC:rl] -is_a: GO:0005515 ! protein binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:39015 ! apolipoprotein -relationship: has_input CHEBI:39015 ! apolipoprotein -relationship: never_in_taxon NCBITaxon:4751 ! Fungi - [Term] id: GO:0034219 name: carbohydrate transmembrane transport @@ -82899,7 +70375,7 @@ synonym: "transmembrane carbohydrate transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0008643 ! carbohydrate transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:16646 ! carbohydrate +intersection_of: has_primary_input CHEBI:16646 intersection_of: results_in_transport_across GO:0016020 ! membrane [Term] @@ -82916,7 +70392,7 @@ synonym: "transmembrane ion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0006811 ! monoatomic ion transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion +intersection_of: has_primary_input CHEBI:24867 intersection_of: results_in_transport_across GO:0016020 ! membrane [Term] @@ -82938,7 +70414,7 @@ namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "regulation of amide metabolism" EXACT [] synonym: "regulation of cellular amide metabolic process" EXACT [] -is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043603 ! amide metabolic process relationship: regulates GO:0043603 ! amide metabolic process @@ -82950,8 +70426,8 @@ namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "negative regulation of amide metabolism" EXACT [] synonym: "negative regulation of cellular amide metabolic process" EXACT [] +is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0034248 ! regulation of amide metabolic process -is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0043603 ! amide metabolic process relationship: negatively_regulates GO:0043603 ! amide metabolic process @@ -82963,8 +70439,8 @@ namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "positive regulation of amide metabolism" EXACT [] synonym: "positive regulation of cellular amide metabolic process" EXACT [] +is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0034248 ! regulation of amide metabolic process -is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043603 ! amide metabolic process relationship: positively_regulates GO:0043603 ! amide metabolic process @@ -83016,17 +70492,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043605 ! amide catabolic process relationship: positively_regulates GO:0043605 ! amide catabolic process -[Term] -id: GO:0034284 -name: response to monosaccharide -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus." [GOC:mah] -synonym: "response to monosaccharide stimulus" EXACT [GOC:dos] -is_a: GO:0009743 ! response to carbohydrate -intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:35381 ! monosaccharide -relationship: has_input CHEBI:35381 ! monosaccharide - [Term] id: GO:0034293 name: sexual sporulation @@ -83040,7 +70505,6 @@ is_a: GO:0043934 ! sporulation intersection_of: GO:0043934 ! sporulation intersection_of: part_of GO:0051321 ! meiotic cell cycle relationship: never_in_taxon NCBITaxon:33083 ! Dictyostelia -relationship: part_of GO:0019953 ! sexual reproduction relationship: part_of GO:0051321 ! meiotic cell cycle [Term] @@ -83094,49 +70558,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030437 ! ascospore formation relationship: regulates GO:0030437 ! ascospore formation -[Term] -id: GO:0034308 -name: primary alcohol metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." [GOC:mah] -synonym: "monohydric alcohol metabolic process" EXACT [] -synonym: "primary alcohol metabolism" EXACT [GOC:mah] -is_a: GO:0006066 ! alcohol metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:15734 ! primary alcohol -relationship: has_primary_input_or_output CHEBI:15734 ! primary alcohol - -[Term] -id: GO:0034309 -name: primary alcohol biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." [GOC:mah] -synonym: "monohydric alcohol biosynthetic process" EXACT [] -synonym: "primary alcohol anabolism" EXACT [GOC:mah] -synonym: "primary alcohol biosynthesis" EXACT [GOC:mah] -synonym: "primary alcohol formation" EXACT [GOC:mah] -synonym: "primary alcohol synthesis" EXACT [GOC:mah] -is_a: GO:0034308 ! primary alcohol metabolic process -is_a: GO:0046165 ! alcohol biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:15734 ! primary alcohol -relationship: has_primary_output CHEBI:15734 ! primary alcohol - -[Term] -id: GO:0034310 -name: primary alcohol catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." [GOC:mah] -synonym: "monohydric alcohol catabolic process" EXACT [] -synonym: "primary alcohol breakdown" EXACT [GOC:mah] -synonym: "primary alcohol catabolism" EXACT [GOC:mah] -synonym: "primary alcohol degradation" EXACT [GOC:mah] -is_a: GO:0034308 ! primary alcohol metabolic process -is_a: GO:0046164 ! alcohol catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:15734 ! primary alcohol -relationship: has_primary_input CHEBI:15734 ! primary alcohol - [Term] id: GO:0034329 name: cell junction assembly @@ -83295,11 +70716,10 @@ id: GO:0034436 name: glycoprotein transport namespace: biological_process def: "The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:mah, GOC:rl] -is_a: GO:0015031 ! protein transport -is_a: GO:1901264 ! carbohydrate derivative transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:17089 ! glycoprotein -relationship: has_primary_input CHEBI:17089 ! glycoprotein +intersection_of: has_primary_input CHEBI:17089 +relationship: has_primary_input CHEBI:17089 [Term] id: GO:0034486 @@ -83323,7 +70743,7 @@ comment: Note that this term is not intended for use in annotating lateral movem synonym: "vacuolar amino acid membrane transport" EXACT [] is_a: GO:0003333 ! amino acid transmembrane transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:33709 ! amino acid +intersection_of: has_primary_input CHEBI:33709 intersection_of: results_in_transport_across GO:0005774 ! vacuolar membrane relationship: results_in_transport_across GO:0005774 ! vacuolar membrane @@ -83367,41 +70787,6 @@ intersection_of: results_in_maturation_of UBERON:0001091 ! calcareous tooth relationship: part_of GO:0042476 ! odontogenesis relationship: results_in_maturation_of UBERON:0001091 ! calcareous tooth -[Term] -id: GO:0034599 -name: cellular response to oxidative stress -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:mah] -synonym: "adaptive response to oxidative stress" NARROW [GOC:add, GOC:vk] -is_a: GO:0006979 ! response to oxidative stress -is_a: GO:0062197 ! cellular response to chemical stress - -[Term] -id: GO:0034614 -name: cellular response to reactive oxygen species -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." [GOC:mah] -synonym: "cellular response to active oxygen species" EXACT [] -synonym: "cellular response to AOS" EXACT [] -synonym: "cellular response to reactive oxidative species" EXACT [] -synonym: "cellular response to reactive oxygen intermediate" EXACT [] -synonym: "cellular response to ROI" EXACT [] -synonym: "cellular response to ROS" EXACT [] -is_a: GO:0000302 ! response to reactive oxygen species -is_a: GO:0034599 ! cellular response to oxidative stress -is_a: GO:1901701 ! cellular response to oxygen-containing compound -intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:26523 ! reactive oxygen species - -[Term] -id: GO:0034637 -name: cellular carbohydrate biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells." [GOC:mah] -is_a: GO:0016051 ! carbohydrate biosynthetic process -is_a: GO:0044249 ! cellular biosynthetic process -is_a: GO:0044262 ! cellular carbohydrate metabolic process - [Term] id: GO:0034641 name: cellular nitrogen compound metabolic process @@ -83412,21 +70797,6 @@ synonym: "cellular nitrogen compound metabolism" EXACT [] is_a: GO:0006807 ! nitrogen compound metabolic process is_a: GO:0044237 ! cellular metabolic process -[Term] -id: GO:0034645 -name: cellular macromolecule biosynthetic process -namespace: biological_process -alt_id: GO:0034961 -def: "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells." [GOC:mah] -synonym: "cellular biopolymer biosynthetic process" EXACT [GOC:mtg_chebi_dec09] -synonym: "cellular macromolecule anabolism" EXACT [GOC:mah] -synonym: "cellular macromolecule biosynthesis" EXACT [GOC:mah] -synonym: "cellular macromolecule formation" EXACT [GOC:mah] -synonym: "cellular macromolecule synthesis" EXACT [GOC:mah] -is_a: GO:0009059 ! macromolecule biosynthetic process -is_a: GO:0044249 ! cellular biosynthetic process -is_a: GO:0044260 ! cellular macromolecule metabolic process - [Term] id: GO:0034654 name: nucleobase-containing compound biosynthetic process @@ -83437,13 +70807,10 @@ synonym: "nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis" EXAC synonym: "nucleobase, nucleoside, nucleotide and nucleic acid formation" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid synthesis" NARROW [] is_a: GO:0006139 ! nucleobase-containing compound metabolic process -is_a: GO:0018130 ! heterocycle biosynthetic process -is_a: GO:0019438 ! aromatic compound biosynthetic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process -is_a: GO:1901362 ! organic cyclic compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:61120 ! nucleobase-containing molecular entity -relationship: has_primary_output CHEBI:61120 ! nucleobase-containing molecular entity +intersection_of: has_primary_output CHEBI:61120 +relationship: has_primary_output CHEBI:61120 [Term] id: GO:0034655 @@ -83456,13 +70823,10 @@ synonym: "nucleobase, nucleoside, nucleotide and nucleic acid catabolic process" synonym: "nucleobase, nucleoside, nucleotide and nucleic acid catabolism" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid degradation" EXACT [] is_a: GO:0006139 ! nucleobase-containing compound metabolic process -is_a: GO:0019439 ! aromatic compound catabolic process is_a: GO:0044270 ! cellular nitrogen compound catabolic process -is_a: GO:0046700 ! heterocycle catabolic process -is_a: GO:1901361 ! organic cyclic compound catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity -relationship: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity +intersection_of: has_primary_input CHEBI:61120 +relationship: has_primary_input CHEBI:61120 [Term] id: GO:0034672 @@ -83477,20 +70841,21 @@ intersection_of: part_of GO:0048793 ! pronephros development [Term] id: GO:0034702 -name: ion channel complex +name: monoatomic ion channel complex namespace: cellular_component -def: "A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient." [GOC:mah, ISBN:071673706X] +def: "A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective monoatomic ion transport down its electrochemical gradient." [GOC:mah, ISBN:071673706X] is_a: GO:1902495 ! transmembrane transporter complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of GO:0005216 ! monoatomic ion channel activity relationship: capable_of GO:0005216 ! monoatomic ion channel activity +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20026" xsd:anyURI [Term] id: GO:0034703 name: cation channel complex namespace: cellular_component def: "An ion channel complex through which cations pass." [GOC:mah] -is_a: GO:0034702 ! ion channel complex +is_a: GO:0034702 ! monoatomic ion channel complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of GO:0005261 ! monoatomic cation channel activity relationship: capable_of GO:0005261 ! monoatomic cation channel activity @@ -83505,16 +70870,6 @@ intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of GO:0005262 ! calcium channel activity relationship: capable_of GO:0005262 ! calcium channel activity -[Term] -id: GO:0034706 -name: sodium channel complex -namespace: cellular_component -def: "An ion channel complex through which sodium ions pass." [GOC:mah] -is_a: GO:0034703 ! cation channel complex -intersection_of: GO:0032991 ! protein-containing complex -intersection_of: capable_of GO:0005272 ! sodium channel activity -relationship: capable_of GO:0005272 ! sodium channel activity - [Term] id: GO:0034755 name: iron ion transmembrane transport @@ -83539,8 +70894,7 @@ synonym: "low-affinity iron ion transmembrane transport" NARROW [] synonym: "low-affinity iron ion transport" NARROW [] synonym: "transmembrane iron transport" EXACT [] is_a: GO:0006826 ! iron ion transport -is_a: GO:0098655 ! monoatomic cation transmembrane transport -is_a: GO:0098662 ! inorganic cation transmembrane transport +is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006826 ! iron ion transport intersection_of: results_in_transport_across GO:0016020 ! membrane created_by: vw @@ -83556,7 +70910,7 @@ synonym: "regulation of Fe transport" EXACT [] synonym: "regulation of iron import" NARROW [GOC:TermGenie] synonym: "regulation of iron ion import" NARROW [] synonym: "regulation of iron transport" EXACT [] -is_a: GO:0010959 ! regulation of metal ion transport +is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006826 ! iron ion transport relationship: regulates GO:0006826 ! iron ion transport @@ -83574,7 +70928,7 @@ synonym: "downregulation of iron ion transport" EXACT [] synonym: "inhibition of iron ion transport" NARROW [] synonym: "negative regulation of iron transport" EXACT [] is_a: GO:0034756 ! regulation of iron ion transport -is_a: GO:0043271 ! negative regulation of monoatomic ion transport +is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006826 ! iron ion transport relationship: negatively_regulates GO:0006826 ! iron ion transport @@ -83591,7 +70945,7 @@ synonym: "up regulation of iron ion transport" EXACT [] synonym: "up-regulation of iron ion transport" EXACT [] synonym: "upregulation of iron ion transport" EXACT [] is_a: GO:0034756 ! regulation of iron ion transport -is_a: GO:0043270 ! positive regulation of monoatomic ion transport +is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006826 ! iron ion transport relationship: positively_regulates GO:0006826 ! iron ion transport @@ -83606,7 +70960,7 @@ synonym: "regulation of transmembrane Fe transport" EXACT [] synonym: "regulation of transmembrane iron ion transport" EXACT [GOC:dph, GOC:tb] synonym: "regulation of transmembrane iron transport" EXACT [] is_a: GO:0034756 ! regulation of iron ion transport -is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport +is_a: GO:0034762 ! regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0034755 ! iron ion transmembrane transport relationship: regulates GO:0034755 ! iron ion transmembrane transport @@ -83625,7 +70979,7 @@ synonym: "negative regulation of transmembrane iron ion transport" EXACT [GOC:dp synonym: "negative regulation of transmembrane iron transport" EXACT [] is_a: GO:0034757 ! negative regulation of iron ion transport is_a: GO:0034759 ! regulation of iron ion transmembrane transport -is_a: GO:1904063 ! negative regulation of cation transmembrane transport +is_a: GO:0034763 ! negative regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0034755 ! iron ion transmembrane transport relationship: negatively_regulates GO:0034755 ! iron ion transmembrane transport @@ -83645,7 +70999,7 @@ synonym: "up-regulation of transmembrane iron ion transport" EXACT [] synonym: "upregulation of transmembrane iron ion transport" EXACT [] is_a: GO:0034758 ! positive regulation of iron ion transport is_a: GO:0034759 ! regulation of iron ion transmembrane transport -is_a: GO:1904064 ! positive regulation of cation transmembrane transport +is_a: GO:0034764 ! positive regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0034755 ! iron ion transmembrane transport relationship: positively_regulates GO:0034755 ! iron ion transmembrane transport @@ -83772,10 +71126,10 @@ name: response to histamine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter." [GOC:BHF, GOC:mah, GOC:vk] synonym: "response to histamine stimulus" EXACT [] -is_a: GO:1901698 ! response to nitrogen compound +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:58432 ! histaminium -relationship: has_input CHEBI:58432 ! histaminium +intersection_of: has_input CHEBI:58432 +relationship: has_input CHEBI:58432 [Term] id: GO:0035010 @@ -84257,10 +71611,10 @@ id: GO:0035240 name: dopamine binding namespace: molecular_function def: "Binding to dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine." [ISBN:0198506732] -is_a: GO:0043169 ! cation binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:59905 ! dopaminium(1+) -relationship: has_input CHEBI:59905 ! dopaminium(1+) +intersection_of: has_input CHEBI:59905 +relationship: has_input CHEBI:59905 [Term] id: GO:0035249 @@ -84441,11 +71795,10 @@ id: GO:0035374 name: chondroitin sulfate binding namespace: molecular_function def: "Binding to chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc)." [GOC:kmv, ISBN:0198506732] -is_a: GO:0005539 ! glycosaminoglycan binding -is_a: GO:1901681 ! sulfur compound binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:37397 ! chondroitin sulfate -relationship: has_input CHEBI:37397 ! chondroitin sulfate +intersection_of: has_input CHEBI:37397 +relationship: has_input CHEBI:37397 created_by: bf creation_date: 2010-03-12T10:25:34Z @@ -84457,7 +71810,7 @@ def: "The directed movement of water (H2O) from one side of an epithelium to the is_a: GO:0006833 ! water transport is_a: GO:0042045 ! epithelial fluid transport intersection_of: GO:0042044 ! fluid transport -intersection_of: has_primary_input CHEBI:15377 ! water +intersection_of: has_primary_input CHEBI:15377 intersection_of: results_in_transport_across UBERON:0000483 ! epithelium created_by: bf creation_date: 2010-03-18T10:55:38Z @@ -84475,36 +71828,6 @@ relationship: has_target_end_location GO:0045202 ! synapse created_by: bf creation_date: 2010-03-29T10:58:53Z -[Term] -id: GO:0035433 -name: acetate transmembrane transport -namespace: biological_process -def: "The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid." [GOC:vw] -comment: Note that this term is not intended for use in annotating lateral movement within membranes. -synonym: "acetate membrane transport" EXACT [] -is_a: GO:0006846 ! acetate transport -is_a: GO:1905039 ! carboxylic acid transmembrane transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:30089 ! acetate -intersection_of: results_in_transport_across GO:0016020 ! membrane -created_by: bf -creation_date: 2010-04-08T10:59:01Z - -[Term] -id: GO:0035435 -name: phosphate ion transmembrane transport -namespace: biological_process -def: "The process in which a phosphate is transported across a membrane." [GOC:vw] -comment: Note that this term is not intended for use in annotating lateral movement within membranes. -synonym: "phosphate ion membrane transport" EXACT [] -is_a: GO:0006817 ! phosphate ion transport -is_a: GO:0098661 ! inorganic anion transmembrane transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:35780 ! phosphate ion -intersection_of: results_in_transport_across GO:0016020 ! membrane -created_by: bf -creation_date: 2010-04-08T11:24:06Z - [Term] id: GO:0035441 name: cell migration involved in vasculogenesis @@ -84895,21 +72218,6 @@ relationship: has_input CL:0000546 ! T-helper 2 cell created_by: bf creation_date: 2011-03-02T03:05:59Z -[Term] -id: GO:0035725 -name: sodium ion transmembrane transport -namespace: biological_process -def: "A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:vw] -comment: Note that this term is not intended for use in annotating lateral movement within membranes. -synonym: "sodium ion membrane transport" EXACT [] -is_a: GO:0006814 ! sodium ion transport -is_a: GO:0098655 ! monoatomic cation transmembrane transport -is_a: GO:0098662 ! inorganic cation transmembrane transport -intersection_of: GO:0055085 ! transmembrane transport -intersection_of: has_primary_input CHEBI:29101 ! sodium(1+) -created_by: bf -creation_date: 2011-03-10T02:52:36Z - [Term] id: GO:0035733 name: hepatic stellate cell activation @@ -85272,36 +72580,6 @@ is_a: GO:0050878 ! regulation of body fluid levels created_by: bf creation_date: 2011-04-20T01:17:38Z -[Term] -id: GO:0035834 -name: indole alkaloid metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton." [GOC:yaf] -synonym: "indole alkaloid metabolism" EXACT [GOC:bf] -is_a: GO:0009820 ! alkaloid metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:38958 ! indole alkaloid -relationship: has_primary_input_or_output CHEBI:38958 ! indole alkaloid -created_by: bf -creation_date: 2011-05-04T03:17:44Z - -[Term] -id: GO:0035835 -name: indole alkaloid biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton." [GOC:yaf] -synonym: "indole alkaloid anabolism" EXACT [GOC:bf] -synonym: "indole alkaloid biosynthesis" EXACT [GOC:bf] -synonym: "indole alkaloid formation" EXACT [GOC:bf] -synonym: "indole alkaloid synthesis" EXACT [GOC:bf] -is_a: GO:0009821 ! alkaloid biosynthetic process -is_a: GO:0035834 ! indole alkaloid metabolic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:38958 ! indole alkaloid -relationship: has_primary_output CHEBI:38958 ! indole alkaloid -created_by: bf -creation_date: 2011-05-04T03:18:31Z - [Term] id: GO:0035844 name: cloaca development @@ -85381,7 +72659,6 @@ namespace: biological_process def: "The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow." [CL:0000556, GOC:BHF, GOC:vk] synonym: "megakaryocyte cell development" EXACT [GOC:bf] is_a: GO:0061515 ! myeloid cell development -is_a: GO:0098751 ! bone cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of CL:0000556 ! megakaryocyte relationship: part_of GO:0030219 ! megakaryocyte differentiation @@ -85593,8 +72870,8 @@ def: "The regulated release of any steroid that acts as a hormone into the circu is_a: GO:0060986 ! endocrine hormone secretion is_a: GO:0140353 ! lipid export from cell intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:26764 ! steroid hormone -relationship: has_primary_input CHEBI:26764 ! steroid hormone +intersection_of: has_primary_input CHEBI:26764 +relationship: has_primary_input CHEBI:26764 created_by: bf creation_date: 2011-07-20T01:01:00Z @@ -85606,8 +72883,8 @@ def: "The regulated release of any corticosteroid hormone into the circulatory s synonym: "corticosteroid secretion" BROAD [GOC:bf] is_a: GO:0035929 ! steroid hormone secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:36699 ! corticosteroid hormone -relationship: has_primary_input CHEBI:36699 ! corticosteroid hormone +intersection_of: has_primary_input CHEBI:36699 +relationship: has_primary_input CHEBI:36699 created_by: bf creation_date: 2011-07-20T01:03:22Z @@ -85618,8 +72895,8 @@ namespace: biological_process def: "The regulated release of any mineralocorticoid into the circulatory system. Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism." [GOC:sl] is_a: GO:0035930 ! corticosteroid hormone secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:25354 ! mineralocorticoid -relationship: has_primary_input CHEBI:25354 ! mineralocorticoid +intersection_of: has_primary_input CHEBI:25354 +relationship: has_primary_input CHEBI:25354 created_by: bf creation_date: 2011-07-20T01:04:59Z @@ -85631,8 +72908,8 @@ def: "The regulated release of aldosterone into the circulatory system. Aldoster is_a: GO:0015850 ! organic hydroxy compound transport is_a: GO:0035931 ! mineralocorticoid secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:27584 ! aldosterone -relationship: has_primary_input CHEBI:27584 ! aldosterone +intersection_of: has_primary_input CHEBI:27584 +relationship: has_primary_input CHEBI:27584 created_by: bf creation_date: 2011-07-20T01:06:24Z @@ -85643,8 +72920,8 @@ namespace: biological_process def: "The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood." [GOC:sl] is_a: GO:0035930 ! corticosteroid hormone secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:24261 ! glucocorticoid -relationship: has_primary_input CHEBI:24261 ! glucocorticoid +intersection_of: has_primary_input CHEBI:24261 +relationship: has_primary_input CHEBI:24261 created_by: bf creation_date: 2011-07-20T01:08:37Z @@ -85662,39 +72939,23 @@ id: GO:0035936 name: testosterone secretion namespace: biological_process def: "The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5." [GOC:sl, PMID:12606499] -is_a: GO:0015850 ! organic hydroxy compound transport is_a: GO:0046879 ! hormone secretion -is_a: GO:0140353 ! lipid export from cell intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:17347 ! testosterone -relationship: has_primary_input CHEBI:17347 ! testosterone +intersection_of: has_primary_input CHEBI:17347 +relationship: has_primary_input CHEBI:17347 created_by: bf creation_date: 2011-07-20T01:13:13Z -[Term] -id: GO:0035937 -name: estrogen secretion -namespace: biological_process -def: "The regulated release of estrogen into the circulatory system. Estrogen is a steroid hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals." [GOC:sl] -synonym: "oestrogen secretion" RELATED [] -is_a: GO:0035929 ! steroid hormone secretion -intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:50114 ! estrogen -relationship: has_primary_input CHEBI:50114 ! estrogen -created_by: bf -creation_date: 2011-07-20T01:14:44Z - [Term] id: GO:0035938 name: estradiol secretion namespace: biological_process def: "The regulated release of estradiol into the circulatory system." [GOC:sl, PMID:21632818] synonym: "oestradiol secretion" EXACT [] -is_a: GO:0015850 ! organic hydroxy compound transport is_a: GO:0035929 ! steroid hormone secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:23965 ! estradiol -relationship: has_primary_input CHEBI:23965 ! estradiol +intersection_of: has_primary_input CHEBI:23965 +relationship: has_primary_input CHEBI:23965 created_by: bf creation_date: 2011-07-20T01:16:45Z @@ -85932,8 +73193,8 @@ namespace: biological_process def: "The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell." [GOC:cjm] is_a: GO:0030072 ! peptide hormone secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:3306 ! calcitonin -relationship: has_primary_input CHEBI:3306 ! calcitonin +intersection_of: has_primary_input CHEBI:3306 +relationship: has_primary_input CHEBI:3306 created_by: bf creation_date: 2012-03-26T01:30:32Z @@ -86001,7 +73262,6 @@ alt_id: GO:0006464 def: "The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." [GOC:bf, GOC:jl] subset: goslim_candida subset: goslim_chembl -subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: prokaryote_subset @@ -86072,8 +73332,8 @@ def: "The regulated release of ghrelin from a cell. Ghrelin is a 28 amino acid h synonym: "pancreatic ghrelin secretion" NARROW [GOC:cjm] is_a: GO:0030072 ! peptide hormone secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:75431 ! ghrelin -relationship: has_primary_input CHEBI:75431 ! ghrelin +intersection_of: has_primary_input CHEBI:75431 +relationship: has_primary_input CHEBI:75431 created_by: bf creation_date: 2012-09-04T14:16:43Z @@ -86319,7 +73579,7 @@ synonym: "SRIF signaling pathway" EXACT [Wikipedia:Somatostatin] synonym: "SST signaling pathway" EXACT [Wikipedia:Somatostatin] is_a: GO:0009755 ! hormone-mediated signaling pathway is_a: GO:0038169 ! somatostatin receptor signaling pathway -relationship: has_input CHEBI:64628 ! somatostatin +relationship: has_input CHEBI:64628 created_by: bf creation_date: 2012-06-12T10:33:21Z @@ -86762,7 +74022,7 @@ name: regulation of dopamine metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine." [GOC:go_curators] synonym: "regulation of dopamine metabolism" EXACT [] -is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042417 ! dopamine metabolic process relationship: regulates GO:0042417 ! dopamine metabolic process @@ -87167,10 +74427,10 @@ name: lipoprotein metabolic process namespace: biological_process def: "The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids." [ISBN:0198506732] synonym: "lipoprotein metabolism" EXACT [] -is_a: GO:0019538 ! protein metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:6495 ! lipoprotein -relationship: has_primary_input_or_output CHEBI:6495 ! lipoprotein +intersection_of: has_primary_input_or_output CHEBI:6495 +relationship: has_primary_input_or_output CHEBI:6495 [Term] id: GO:0042158 @@ -87182,12 +74442,11 @@ synonym: "lipoprotein anabolism" EXACT [] synonym: "lipoprotein biosynthesis" EXACT [] synonym: "lipoprotein formation" EXACT [] synonym: "lipoprotein synthesis" EXACT [] -is_a: GO:0034645 ! cellular macromolecule biosynthetic process +is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0042157 ! lipoprotein metabolic process -is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:6495 ! lipoprotein -relationship: has_primary_output CHEBI:6495 ! lipoprotein +intersection_of: has_primary_output CHEBI:6495 +relationship: has_primary_output CHEBI:6495 [Term] id: GO:0042159 @@ -87197,11 +74456,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of any conj synonym: "lipoprotein breakdown" EXACT [] synonym: "lipoprotein catabolism" EXACT [] synonym: "lipoprotein degradation" EXACT [] -is_a: GO:0030163 ! protein catabolic process +is_a: GO:0009056 ! catabolic process is_a: GO:0042157 ! lipoprotein metabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:6495 ! lipoprotein -relationship: has_primary_input CHEBI:6495 ! lipoprotein +intersection_of: has_primary_input CHEBI:6495 +relationship: has_primary_input CHEBI:6495 [Term] id: GO:0042165 @@ -87217,10 +74476,9 @@ name: acetylcholine binding namespace: molecular_function def: "Binding to acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai] is_a: GO:0042165 ! neurotransmitter binding -is_a: GO:0043169 ! cation binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:15355 ! acetylcholine -relationship: has_input CHEBI:15355 ! acetylcholine +intersection_of: has_input CHEBI:15355 +relationship: has_input CHEBI:15355 [Term] id: GO:0042173 @@ -87343,8 +74601,8 @@ is_a: GO:0044237 ! cellular metabolic process is_a: GO:0044281 ! small molecule metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:17087 ! ketone -relationship: has_primary_input_or_output CHEBI:17087 ! ketone +intersection_of: has_primary_input_or_output CHEBI:17087 +relationship: has_primary_input_or_output CHEBI:17087 [Term] id: GO:0042181 @@ -87360,8 +74618,8 @@ is_a: GO:0044249 ! cellular biosynthetic process is_a: GO:0044283 ! small molecule biosynthetic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:17087 ! ketone -relationship: has_primary_output CHEBI:17087 ! ketone +intersection_of: has_primary_output CHEBI:17087 +relationship: has_primary_output CHEBI:17087 [Term] id: GO:0042182 @@ -87374,38 +74632,9 @@ synonym: "ketone degradation" EXACT [] is_a: GO:0042180 ! cellular ketone metabolic process is_a: GO:0044248 ! cellular catabolic process is_a: GO:0044282 ! small molecule catabolic process -is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:17087 ! ketone -relationship: has_primary_input CHEBI:17087 ! ketone - -[Term] -id: GO:0042183 -name: formate catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid." [ISBN:0198506732] -synonym: "formate breakdown" EXACT [] -synonym: "formate catabolism" EXACT [] -synonym: "formate degradation" EXACT [] -synonym: "formic acid catabolic process" EXACT [] -synonym: "formic acid catabolism" EXACT [] -is_a: GO:0015942 ! formate metabolic process -is_a: GO:0072329 ! monocarboxylic acid catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:15740 ! formate -relationship: has_primary_input CHEBI:15740 ! formate - -[Term] -id: GO:0042214 -name: terpene metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups." [GOC:curators] -synonym: "terpene metabolism" EXACT [] -is_a: GO:0006720 ! isoprenoid metabolic process -is_a: GO:0120252 ! hydrocarbon metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:35186 ! terpene -relationship: has_primary_input_or_output CHEBI:35186 ! terpene +intersection_of: has_primary_input CHEBI:17087 +relationship: has_primary_input CHEBI:17087 [Term] id: GO:0042219 @@ -87423,10 +74652,10 @@ synonym: "cellular modified amino acid degradation" EXACT [GOC:mah] synonym: "modified amino acid catabolic process" EXACT [GOC:mah] synonym: "modified amino acid catabolism" EXACT [GOC:mah] is_a: GO:0006575 ! cellular modified amino acid metabolic process -is_a: GO:1901565 ! organonitrogen compound catabolic process +is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:83821 ! amino acid derivative -relationship: has_primary_input CHEBI:83821 ! amino acid derivative +intersection_of: has_primary_input CHEBI:83821 +relationship: has_primary_input CHEBI:83821 [Term] id: GO:0042221 @@ -87444,8 +74673,8 @@ synonym: "response to chemical stimulus" EXACT [GOC:dos] synonym: "response to chemical substance" EXACT [] is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:24431 ! chemical entity -relationship: has_input CHEBI:24431 ! chemical entity +intersection_of: has_input CHEBI:24431 +relationship: has_input CHEBI:24431 [Term] id: GO:0042246 @@ -87535,10 +74764,10 @@ namespace: molecular_function def: "Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds." [GOC:jl] subset: goslim_chembl subset: goslim_pir -is_a: GO:0033218 ! amide binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:16670 ! peptide -relationship: has_input CHEBI:16670 ! peptide +intersection_of: has_input CHEBI:16670 +relationship: has_input CHEBI:16670 [Term] id: GO:0042287 @@ -87550,16 +74779,6 @@ synonym: "major histocompatibility complex binding" EXACT [] synonym: "major histocompatibility complex ligand" NARROW [] is_a: GO:0005102 ! signaling receptor binding -[Term] -id: GO:0042301 -name: phosphate ion binding -namespace: molecular_function -def: "Binding to a phosphate ion." [GOC:jl] -is_a: GO:0043168 ! anion binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:35780 ! phosphate ion -relationship: has_input CHEBI:35780 ! phosphate ion - [Term] id: GO:0042303 name: molting cycle @@ -87569,22 +74788,6 @@ subset: goslim_drosophila subset: goslim_pir is_a: GO:0032501 ! multicellular organismal process -[Term] -id: GO:0042304 -name: regulation of fatty acid biosynthetic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils." [GOC:go_curators, GOC:jl] -synonym: "regulation of fatty acid anabolism" EXACT [] -synonym: "regulation of fatty acid biosynthesis" EXACT [] -synonym: "regulation of fatty acid formation" EXACT [] -synonym: "regulation of fatty acid synthesis" EXACT [] -is_a: GO:0019217 ! regulation of fatty acid metabolic process -is_a: GO:0031326 ! regulation of cellular biosynthetic process -is_a: GO:0046890 ! regulation of lipid biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0006633 ! fatty acid biosynthetic process -relationship: regulates GO:0006633 ! fatty acid biosynthetic process - [Term] id: GO:0042325 name: regulation of phosphorylation @@ -87644,11 +74847,10 @@ def: "The chemical reactions and pathways involving keratan sulfate, a glycosami synonym: "keratan sulfate metabolism" EXACT [] synonym: "keratan sulphate metabolic process" EXACT [] synonym: "keratan sulphate metabolism" EXACT [] -is_a: GO:0006790 ! sulfur compound metabolic process -is_a: GO:1903510 ! mucopolysaccharide metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:60924 ! keratan sulfate -relationship: has_primary_input_or_output CHEBI:60924 ! keratan sulfate +intersection_of: has_primary_input_or_output CHEBI:60924 +relationship: has_primary_input_or_output CHEBI:60924 [Term] id: GO:0042340 @@ -87660,12 +74862,11 @@ synonym: "keratan sulfate catabolism" EXACT [] synonym: "keratan sulfate degradation" EXACT [] synonym: "keratan sulphate catabolic process" EXACT [] synonym: "keratan sulphate catabolism" EXACT [] -is_a: GO:0006027 ! glycosaminoglycan catabolic process +is_a: GO:0009056 ! catabolic process is_a: GO:0042339 ! keratan sulfate metabolic process -is_a: GO:0044273 ! sulfur compound catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:60924 ! keratan sulfate -relationship: has_primary_input CHEBI:60924 ! keratan sulfate +intersection_of: has_primary_input CHEBI:60924 +relationship: has_primary_input CHEBI:60924 [Term] id: GO:0042379 @@ -87727,10 +74928,10 @@ synonym: "cellular modified amino acid biosynthesis" EXACT [GOC:mah] synonym: "cellular modified amino acid formation" EXACT [GOC:mah] synonym: "cellular modified amino acid synthesis" EXACT [GOC:mah] is_a: GO:0006575 ! cellular modified amino acid metabolic process -is_a: GO:1901566 ! organonitrogen compound biosynthetic process +is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:83821 ! amino acid derivative -relationship: has_primary_output CHEBI:83821 ! amino acid derivative +intersection_of: has_primary_output CHEBI:83821 +relationship: has_primary_output CHEBI:83821 [Term] id: GO:0042401 @@ -87773,10 +74974,10 @@ def: "The chemical reactions and pathways involving epinephrine, a hormone produ synonym: "adrenaline metabolic process" EXACT [] synonym: "adrenaline metabolism" EXACT [] synonym: "epinephrine metabolism" EXACT [] -is_a: GO:0006584 ! catecholamine metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:33568 ! adrenaline -relationship: has_primary_input_or_output CHEBI:33568 ! adrenaline +intersection_of: has_primary_input_or_output CHEBI:33568 +relationship: has_primary_input_or_output CHEBI:33568 [Term] id: GO:0042415 @@ -87788,11 +74989,10 @@ synonym: "levarterenol metabolism" EXACT [] synonym: "noradrenaline metabolic process" EXACT [] synonym: "noradrenaline metabolism" EXACT [] synonym: "norepinephrine metabolism" EXACT [] -is_a: GO:0006807 ! nitrogen compound metabolic process -is_a: GO:0071704 ! organic substance metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:72587 ! (R)-noradrenaline(1+) -relationship: has_primary_input_or_output CHEBI:72587 ! (R)-noradrenaline(1+) +intersection_of: has_primary_input_or_output CHEBI:72587 +relationship: has_primary_input_or_output CHEBI:72587 [Term] id: GO:0042416 @@ -87806,8 +75006,8 @@ synonym: "dopamine synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0042417 ! dopamine metabolic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:59905 ! dopaminium(1+) -relationship: has_primary_output CHEBI:59905 ! dopaminium(1+) +intersection_of: has_primary_output CHEBI:59905 +relationship: has_primary_output CHEBI:59905 [Term] id: GO:0042417 @@ -87815,10 +75015,10 @@ name: dopamine metabolic process namespace: biological_process def: "The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." [GOC:jl, ISBN:0198506732] synonym: "dopamine metabolism" EXACT [] -is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:59905 ! dopaminium(1+) -relationship: has_primary_input_or_output CHEBI:59905 ! dopaminium(1+) +intersection_of: has_primary_input_or_output CHEBI:59905 +relationship: has_primary_input_or_output CHEBI:59905 [Term] id: GO:0042418 @@ -87831,11 +75031,11 @@ synonym: "epinephrine anabolism" EXACT [] synonym: "epinephrine biosynthesis" EXACT [] synonym: "epinephrine formation" EXACT [] synonym: "epinephrine synthesis" EXACT [] +is_a: GO:0009058 ! biosynthetic process is_a: GO:0042414 ! epinephrine metabolic process -is_a: GO:0042423 ! catecholamine biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:33568 ! adrenaline -relationship: has_primary_output CHEBI:33568 ! adrenaline +intersection_of: has_primary_output CHEBI:33568 +relationship: has_primary_output CHEBI:33568 [Term] id: GO:0042419 @@ -87847,11 +75047,11 @@ synonym: "adrenaline catabolism" EXACT [] synonym: "epinephrine breakdown" EXACT [] synonym: "epinephrine catabolism" EXACT [] synonym: "epinephrine degradation" EXACT [] +is_a: GO:0009056 ! catabolic process is_a: GO:0042414 ! epinephrine metabolic process -is_a: GO:0042424 ! catecholamine catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:33568 ! adrenaline -relationship: has_primary_input CHEBI:33568 ! adrenaline +intersection_of: has_primary_input CHEBI:33568 +relationship: has_primary_input CHEBI:33568 [Term] id: GO:0042420 @@ -87864,8 +75064,8 @@ synonym: "dopamine degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0042417 ! dopamine metabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:59905 ! dopaminium(1+) -relationship: has_primary_input CHEBI:59905 ! dopaminium(1+) +intersection_of: has_primary_input CHEBI:59905 +relationship: has_primary_input CHEBI:59905 [Term] id: GO:0042421 @@ -87880,11 +75080,11 @@ synonym: "norepinephrine anabolism" EXACT [] synonym: "norepinephrine biosynthesis" EXACT [] synonym: "norepinephrine formation" EXACT [] synonym: "norepinephrine synthesis" EXACT [] +is_a: GO:0009058 ! biosynthetic process is_a: GO:0042415 ! norepinephrine metabolic process -is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:72587 ! (R)-noradrenaline(1+) -relationship: has_primary_output CHEBI:72587 ! (R)-noradrenaline(1+) +intersection_of: has_primary_output CHEBI:72587 +relationship: has_primary_output CHEBI:72587 [Term] id: GO:0042422 @@ -87899,11 +75099,11 @@ synonym: "norepinephrine breakdown" EXACT [] synonym: "norepinephrine catabolism" EXACT [] synonym: "norepinephrine degradation" EXACT [] xref: Wikipedia:Norepinephrine#Degradation +is_a: GO:0009056 ! catabolic process is_a: GO:0042415 ! norepinephrine metabolic process -is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) -relationship: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) +intersection_of: has_primary_input CHEBI:72587 +relationship: has_primary_input CHEBI:72587 [Term] id: GO:0042423 @@ -87916,11 +75116,10 @@ synonym: "catecholamine formation" EXACT [] synonym: "catecholamine synthesis" EXACT [] xref: Wikipedia:Catecholamines is_a: GO:0006584 ! catecholamine metabolic process -is_a: GO:0009713 ! catechol-containing compound biosynthetic process is_a: GO:0042401 ! biogenic amine biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:33567 ! catecholamine -relationship: has_primary_output CHEBI:33567 ! catecholamine +intersection_of: has_primary_output CHEBI:33567 +relationship: has_primary_output CHEBI:33567 [Term] id: GO:0042424 @@ -87931,11 +75130,10 @@ synonym: "catecholamine breakdown" EXACT [] synonym: "catecholamine catabolism" EXACT [] synonym: "catecholamine degradation" EXACT [] is_a: GO:0006584 ! catecholamine metabolic process -is_a: GO:0019614 ! catechol-containing compound catabolic process is_a: GO:0042402 ! cellular biogenic amine catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:33567 ! catecholamine -relationship: has_primary_input CHEBI:33567 ! catecholamine +intersection_of: has_primary_input CHEBI:33567 +relationship: has_primary_input CHEBI:33567 [Term] id: GO:0042427 @@ -87950,8 +75148,8 @@ xref: Wikipedia:Serotonin is_a: GO:0009058 ! biosynthetic process is_a: GO:0042428 ! serotonin metabolic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:350546 ! serotonin(1+) -relationship: has_primary_output CHEBI:350546 ! serotonin(1+) +intersection_of: has_primary_output CHEBI:350546 +relationship: has_primary_output CHEBI:350546 [Term] id: GO:0042428 @@ -87964,8 +75162,8 @@ is_a: GO:0042430 ! indole-containing compound metabolic process is_a: GO:0097164 ! ammonium ion metabolic process is_a: GO:1901160 ! primary amino compound metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:350546 ! serotonin(1+) -relationship: has_primary_input_or_output CHEBI:350546 ! serotonin(1+) +intersection_of: has_primary_input_or_output CHEBI:350546 +relationship: has_primary_input_or_output CHEBI:350546 [Term] id: GO:0042429 @@ -87978,8 +75176,8 @@ synonym: "serotonin degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0042428 ! serotonin metabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:350546 ! serotonin(1+) -relationship: has_primary_input CHEBI:350546 ! serotonin(1+) +intersection_of: has_primary_input CHEBI:350546 +relationship: has_primary_input CHEBI:350546 [Term] id: GO:0042430 @@ -88000,8 +75198,8 @@ is_a: GO:0046483 ! heterocycle metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:24828 ! indoles -relationship: has_primary_input_or_output CHEBI:24828 ! indoles +intersection_of: has_primary_input_or_output CHEBI:24828 +relationship: has_primary_input_or_output CHEBI:24828 [Term] id: GO:0042435 @@ -88021,8 +75219,8 @@ is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:24828 ! indoles -relationship: has_primary_output CHEBI:24828 ! indoles +intersection_of: has_primary_output CHEBI:24828 +relationship: has_primary_output CHEBI:24828 [Term] id: GO:0042436 @@ -88034,15 +75232,11 @@ synonym: "indole derivative catabolism" EXACT [] synonym: "indole-containing compound breakdown" EXACT [] synonym: "indole-containing compound catabolism" EXACT [] synonym: "indole-containing compound degradation" EXACT [] -is_a: GO:0019439 ! aromatic compound catabolic process is_a: GO:0042430 ! indole-containing compound metabolic process is_a: GO:0044270 ! cellular nitrogen compound catabolic process -is_a: GO:0046700 ! heterocycle catabolic process -is_a: GO:1901361 ! organic cyclic compound catabolic process -is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:24828 ! indoles -relationship: has_primary_input CHEBI:24828 ! indoles +intersection_of: has_primary_input CHEBI:24828 +relationship: has_primary_input CHEBI:24828 [Term] id: GO:0042442 @@ -88054,11 +75248,10 @@ synonym: "melatonin breakdown" EXACT [] synonym: "melatonin catabolism" EXACT [] synonym: "melatonin degradation" EXACT [] is_a: GO:0030186 ! melatonin metabolic process -is_a: GO:0042436 ! indole-containing compound catabolic process is_a: GO:0042447 ! hormone catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:16796 ! melatonin -relationship: has_primary_input CHEBI:16796 ! melatonin +intersection_of: has_primary_input CHEBI:16796 +relationship: has_primary_input CHEBI:16796 [Term] id: GO:0042445 @@ -88101,12 +75294,10 @@ name: progesterone metabolic process namespace: biological_process def: "The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants." [GOC:jl, http://www.cogsci.princeton.edu/] synonym: "progesterone metabolism" EXACT [] -is_a: GO:0008207 ! C21-steroid hormone metabolic process -is_a: GO:0042180 ! cellular ketone metabolic process -is_a: GO:0120254 ! olefinic compound metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:17026 ! progesterone -relationship: has_primary_input_or_output CHEBI:17026 ! progesterone +intersection_of: has_primary_input_or_output CHEBI:17026 +relationship: has_primary_input_or_output CHEBI:17026 [Term] id: GO:0042461 @@ -88455,6 +75646,9 @@ comment: Note that an immunoglobulin complex has the function of antigen binding synonym: "antibody" EXACT [GOC:add] xref: Wikipedia:Antibody is_a: GO:0019814 ! immunoglobulin complex +intersection_of: GO:0019814 ! immunoglobulin complex +intersection_of: output_of GO:0032940 ! secretion by cell +relationship: output_of GO:0032940 ! secretion by cell relationship: part_of GO:0005615 ! extracellular space [Term] @@ -88535,10 +75729,10 @@ id: GO:0042593 name: glucose homeostasis namespace: biological_process def: "Any process involved in the maintenance of an internal steady state of glucose within an organism or cell." [GOC:go_curators] -is_a: GO:0033500 ! carbohydrate homeostasis +is_a: GO:0048878 ! chemical homeostasis intersection_of: GO:0048878 ! chemical homeostasis -intersection_of: regulates_levels_of CHEBI:17234 ! glucose -relationship: regulates_levels_of CHEBI:17234 ! glucose +intersection_of: regulates_levels_of CHEBI:17234 +relationship: regulates_levels_of CHEBI:17234 [Term] id: GO:0042608 @@ -88742,8 +75936,8 @@ is_a: GO:0022412 ! cellular process involved in reproduction in multicellular or is_a: GO:0022602 ! ovulation cycle process is_a: GO:0035929 ! steroid hormone secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:17026 ! progesterone -relationship: has_primary_input CHEBI:17026 ! progesterone +intersection_of: has_primary_input CHEBI:17026 +relationship: has_primary_input CHEBI:17026 relationship: part_of GO:0001553 ! luteinization [Term] @@ -88785,19 +75979,6 @@ is_a: GO:0009617 ! response to bacterium intersection_of: GO:0006952 ! defense response intersection_of: has_input NCBITaxon:2 ! Bacteria -[Term] -id: GO:0042762 -name: regulation of sulfur metabolic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur." [GOC:go_curators] -synonym: "regulation of sulfur metabolism" EXACT [] -synonym: "regulation of sulphur metabolic process" EXACT [] -synonym: "regulation of sulphur metabolism" EXACT [] -is_a: GO:0031323 ! regulation of cellular metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0006790 ! sulfur compound metabolic process -relationship: regulates GO:0006790 ! sulfur compound metabolic process - [Term] id: GO:0042886 name: amide transport @@ -88806,8 +75987,8 @@ def: "The directed movement of an amide, any compound containing one, two, or th subset: goslim_pir is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:32988 ! amide -relationship: has_primary_input CHEBI:32988 ! amide +intersection_of: has_primary_input CHEBI:32988 +relationship: has_primary_input CHEBI:32988 [Term] id: GO:0042887 @@ -88817,8 +75998,8 @@ def: "Enables the transfer of an amide, any compound containing one, two, or thr synonym: "amine/amide/polyamine channel activity" NARROW [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:32988 ! amide -relationship: has_primary_input CHEBI:32988 ! amide +intersection_of: has_primary_input CHEBI:32988 +relationship: has_primary_input CHEBI:32988 relationship: part_of GO:0042886 ! amide transport [Term] @@ -88841,10 +76022,10 @@ id: GO:0042953 name: lipoprotein transport namespace: biological_process def: "The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, ISBN:0198506732] -is_a: GO:0015031 ! protein transport +is_a: GO:0006810 ! transport is_a: GO:0044872 ! lipoprotein localization intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:6495 ! lipoprotein +intersection_of: has_primary_input CHEBI:6495 [Term] id: GO:0042981 @@ -89096,11 +76277,10 @@ synonym: "peptide biosynthesis" EXACT [] synonym: "peptide formation" EXACT [] synonym: "peptide synthesis" EXACT [] is_a: GO:0006518 ! peptide metabolic process -is_a: GO:0043604 ! amide biosynthetic process -is_a: GO:1901566 ! organonitrogen compound biosynthetic process +is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:16670 ! peptide -relationship: has_primary_output CHEBI:16670 ! peptide +intersection_of: has_primary_output CHEBI:16670 +relationship: has_primary_output CHEBI:16670 [Term] id: GO:0043049 @@ -89356,56 +76536,22 @@ relationship: part_of GO:0006412 ! translation [Term] id: GO:0043158 -name: heterocyst differentiation +name: heterocyst development namespace: biological_process -def: "The process in which a relatively unspecialized cell acquires specialized features of a heterocyst, a differentiated cell in certain cyanobacteria whose purpose is to fix nitrogen." [GOC:jl] -synonym: "heterocyst biosynthesis" EXACT [] -synonym: "heterocyst cell differentiation" EXACT [] +def: "The cellular developmental process by which a cell becomes a heterocyst, a cell that carries out nitrogen fixation. This process involves changes to the cell wall, expression of nitrogenase and other proteins involved in nitrogen fixation, and degradation of photosystem II, which produces oxygen. This process is known to occur in some cyanobacteria." [PMID:11121783, PMID:35744626] +synonym: "heterocyst cell differentiation" RELATED [] +synonym: "heterocyst differentiation" RELATED [] synonym: "heterocyst formation" EXACT [] -is_a: GO:0030154 ! cell differentiation -intersection_of: GO:0030154 ! cell differentiation -intersection_of: results_in_acquisition_of_features_of CL:0000724 ! heterocyst -relationship: results_in_acquisition_of_features_of CL:0000724 ! heterocyst - -[Term] -id: GO:0043167 -name: ion binding -namespace: molecular_function -def: "Binding to an ion, a charged atoms or groups of atoms." [GOC:jl] -subset: goslim_chembl -subset: goslim_metagenomics -subset: goslim_pir -subset: goslim_yeast -synonym: "atom binding" RELATED [] -is_a: GO:0005488 ! binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:24870 ! ion -relationship: has_input CHEBI:24870 ! ion - -[Term] -id: GO:0043168 -name: anion binding -namespace: molecular_function -def: "Binding to an anion, a charged atom or group of atoms with a net negative charge." [GOC:jl] -is_a: GO:0043167 ! ion binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:22563 ! anion -relationship: has_input CHEBI:22563 ! anion - -[Term] -id: GO:0043169 -name: cation binding -namespace: molecular_function -def: "Binding to a cation, a charged atom or group of atoms with a net positive charge." [GOC:jl] -is_a: GO:0043167 ! ion binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:36916 ! cation -relationship: has_input CHEBI:36916 ! cation +is_a: GO:0048869 ! cellular developmental process +intersection_of: GO:0048869 ! cellular developmental process +intersection_of: results_in_developmental_progression_of CL:0000724 ! heterocyst +relationship: results_in_developmental_progression_of CL:0000724 ! heterocyst [Term] id: GO:0043170 name: macromolecule metabolic process namespace: biological_process +alt_id: GO:0034960 alt_id: GO:0043283 alt_id: GO:0044259 def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] @@ -89414,10 +76560,10 @@ synonym: "biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule metabolism" EXACT [] synonym: "multicellular organismal macromolecule metabolic process" NARROW [] synonym: "organismal macromolecule metabolism" EXACT [] -is_a: GO:0071704 ! organic substance metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:33694 ! biomacromolecule -relationship: has_primary_input_or_output CHEBI:33694 ! biomacromolecule +intersection_of: has_primary_input_or_output CHEBI:33694 +relationship: has_primary_input_or_output CHEBI:33694 [Term] id: GO:0043171 @@ -89429,10 +76575,9 @@ synonym: "peptide catabolism" EXACT [] synonym: "peptide degradation" EXACT [] is_a: GO:0006518 ! peptide metabolic process is_a: GO:0044248 ! cellular catabolic process -is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:16670 ! peptide -relationship: has_primary_input CHEBI:16670 ! peptide +intersection_of: has_primary_input CHEBI:16670 +relationship: has_primary_input CHEBI:16670 [Term] id: GO:0043176 @@ -89442,8 +76587,8 @@ def: "Binding to an amine, a weakly basic organic compound that contains an amin subset: goslim_pir is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:32952 ! amine -relationship: has_input CHEBI:32952 ! amine +intersection_of: has_input CHEBI:32952 +relationship: has_input CHEBI:32952 [Term] id: GO:0043177 @@ -89452,19 +76597,8 @@ namespace: molecular_function def: "Binding to an organic acid, any acidic compound containing carbon in covalent linkage." [GOC:jl, ISBN:0198506732] is_a: GO:0036094 ! small molecule binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:64709 ! organic acid -relationship: has_input CHEBI:64709 ! organic acid - -[Term] -id: GO:0043178 -name: alcohol binding -namespace: molecular_function -def: "Binding to an alcohol, any of a class of alkyl compounds containing a hydroxyl group." [GOC:jl, ISBN:0198506732] -subset: goslim_pir -is_a: GO:0036094 ! small molecule binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:30879 ! alcohol -relationship: has_input CHEBI:30879 ! alcohol +intersection_of: has_input CHEBI:64709 +relationship: has_input CHEBI:64709 [Term] id: GO:0043184 @@ -89494,17 +76628,6 @@ xref: NIF_Subcellular:sao187426937 is_a: GO:0098793 ! presynapse relationship: part_of GO:0043679 ! axon terminus -[Term] -id: GO:0043199 -name: sulfate binding -namespace: molecular_function -def: "Binding to sulfate, SO4(2-), a negatively charged small molecule." [GOC:mlg] -is_a: GO:0043168 ! anion binding -is_a: GO:1901681 ! sulfur compound binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:16189 ! sulfate -relationship: has_input CHEBI:16189 ! sulfate - [Term] id: GO:0043200 name: response to amino acid @@ -89513,11 +76636,9 @@ alt_id: GO:0010237 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups." [GOC:ef, GOC:mlg] synonym: "response to amino acid stimulus" EXACT [GOC:dos] is_a: GO:0001101 ! response to acid chemical -is_a: GO:0010243 ! response to organonitrogen compound -is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:33709 ! amino acid -relationship: has_input CHEBI:33709 ! amino acid +intersection_of: has_input CHEBI:33709 +relationship: has_input CHEBI:33709 [Term] id: GO:0043207 @@ -89532,11 +76653,10 @@ id: GO:0043208 name: glycosphingolipid binding namespace: molecular_function def: "Binding to glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide." [GOC:jl] -is_a: GO:0046625 ! sphingolipid binding -is_a: GO:0051861 ! glycolipid binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:24402 ! glycosphingolipid -relationship: has_input CHEBI:24402 ! glycosphingolipid +intersection_of: has_input CHEBI:24402 +relationship: has_input CHEBI:24402 [Term] id: GO:0043209 @@ -89810,16 +76930,6 @@ synonym: "efferocytosis" EXACT [PMID:17548650] synonym: "programmed cell clearance" EXACT [] is_a: GO:0006909 ! phagocytosis -[Term] -id: GO:0043279 -name: response to alkaloid -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active." [GOC:jl] -is_a: GO:0010243 ! response to organonitrogen compound -intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:22315 ! alkaloid -relationship: has_input CHEBI:22315 ! alkaloid - [Term] id: GO:0043282 name: pharyngeal muscle development @@ -90663,11 +77773,10 @@ id: GO:0043394 name: proteoglycan binding namespace: molecular_function def: "Binding to a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans." [ISBN:0198506732] -is_a: GO:0005515 ! protein binding -is_a: GO:0097367 ! carbohydrate derivative binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:37396 ! proteoglycan -relationship: has_input CHEBI:37396 ! proteoglycan +intersection_of: has_input CHEBI:37396 +relationship: has_input CHEBI:37396 [Term] id: GO:0043401 @@ -90758,10 +77867,9 @@ def: "Any process that results in a change in state or activity of a cell or an synonym: "response to peptide hormone stimulus" EXACT [GOC:dos] synonym: "response to polypeptide hormone stimulus" EXACT [] is_a: GO:0009725 ! response to hormone -is_a: GO:1901652 ! response to peptide intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:25905 ! peptide hormone -relationship: has_input CHEBI:25905 ! peptide hormone +intersection_of: has_input CHEBI:25905 +relationship: has_input CHEBI:25905 [Term] id: GO:0043436 @@ -90777,52 +77885,8 @@ synonym: "oxo acid metabolism" EXACT [] synonym: "oxoacid metabolism" EXACT [] is_a: GO:0006082 ! organic acid metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:35406 ! oxoanion -relationship: has_primary_input_or_output CHEBI:35406 ! oxoanion - -[Term] -id: GO:0043446 -name: cellular alkane metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, as carried out by individual cells." [GOC:jl, Wikipedia:Alkane] -subset: goslim_pir -synonym: "alkane metabolism" EXACT [] -is_a: GO:0044237 ! cellular metabolic process -is_a: GO:0120252 ! hydrocarbon metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:18310 ! alkane -relationship: has_primary_input_or_output CHEBI:18310 ! alkane - -[Term] -id: GO:0043447 -name: alkane biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2." [GOC:jl, Wikipedia:Alkane] -synonym: "alkane anabolism" EXACT [] -synonym: "alkane biosynthesis" EXACT [] -synonym: "alkane formation" EXACT [] -synonym: "alkane synthesis" EXACT [] -is_a: GO:0043446 ! cellular alkane metabolic process -is_a: GO:0044249 ! cellular biosynthetic process -is_a: GO:0120251 ! hydrocarbon biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:18310 ! alkane -relationship: has_primary_output CHEBI:18310 ! alkane - -[Term] -id: GO:0043448 -name: alkane catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2." [GOC:jl, Wikipedia:Alkane] -synonym: "alkane breakdown" EXACT [] -synonym: "alkane catabolism" EXACT [] -synonym: "alkane degradation" EXACT [] -is_a: GO:0043446 ! cellular alkane metabolic process -is_a: GO:0044248 ! cellular catabolic process -is_a: GO:0120253 ! hydrocarbon catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:18310 ! alkane -relationship: has_primary_input CHEBI:18310 ! alkane +intersection_of: has_primary_input_or_output CHEBI:35406 +relationship: has_primary_input_or_output CHEBI:35406 [Term] id: GO:0043455 @@ -90848,16 +77912,6 @@ intersection_of: regulates GO:0140657 ! ATP-dependent activity relationship: regulates GO:0140657 ! ATP-dependent activity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22371" xsd:anyURI -[Term] -id: GO:0043465 -name: regulation of fermentation -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of fermentation, the anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, resulting in energy in the form of adenosine triphosphate (ATP)." [GOC:jl] -is_a: GO:0043467 ! regulation of generation of precursor metabolites and energy -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0006113 ! fermentation -relationship: regulates GO:0006113 ! fermentation - [Term] id: GO:0043467 name: regulation of generation of precursor metabolites and energy @@ -90879,19 +77933,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016052 ! carbohydrate catabolic process relationship: regulates GO:0016052 ! carbohydrate catabolic process -[Term] -id: GO:0043471 -name: regulation of cellular carbohydrate catabolic process -namespace: biological_process -def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates, carried out by individual cells." [GOC:jl] -is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process -is_a: GO:0031329 ! regulation of cellular catabolic process -is_a: GO:0043470 ! regulation of carbohydrate catabolic process -is_a: GO:0060255 ! regulation of macromolecule metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0044275 ! cellular carbohydrate catabolic process -relationship: regulates GO:0044275 ! cellular carbohydrate catabolic process - [Term] id: GO:0043473 name: pigmentation @@ -91076,41 +78117,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016301 ! kinase activity relationship: regulates GO:0016301 ! kinase activity -[Term] -id: GO:0043555 -name: regulation of translation in response to stress -namespace: biological_process -def: "Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:jl] -synonym: "translational stress response" EXACT [] -is_a: GO:0006417 ! regulation of translation -intersection_of: GO:0065007 ! biological regulation -intersection_of: part_of GO:0033554 ! cellular response to stress -intersection_of: regulates GO:0006412 ! translation -relationship: part_of GO:0033554 ! cellular response to stress - -[Term] -id: GO:0043556 -name: regulation of translation in response to oxidative stress -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:jl] -is_a: GO:0032055 ! negative regulation of translation in response to stress -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0006412 ! translation -intersection_of: part_of GO:0034599 ! cellular response to oxidative stress -relationship: part_of GO:0034599 ! cellular response to oxidative stress - -[Term] -id: GO:0043558 -name: regulation of translational initiation in response to stress -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress." [GOC:jl] -synonym: "regulation of translation initiation in response to stress" EXACT [GOC:dph, GOC:hjd, GOC:tb] -is_a: GO:0006446 ! regulation of translational initiation -is_a: GO:0043555 ! regulation of translation in response to stress -intersection_of: GO:0065007 ! biological regulation -intersection_of: part_of GO:0033554 ! cellular response to stress -intersection_of: regulates GO:0006413 ! translational initiation - [Term] id: GO:0043559 name: insulin binding @@ -91225,10 +78231,10 @@ def: "The chemical reactions and pathways involving an amide, any derivative of subset: goslim_pir synonym: "amide metabolism" EXACT [] synonym: "cellular amide metabolic process" EXACT [] -is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:32988 ! amide -relationship: has_primary_input_or_output CHEBI:32988 ! amide +intersection_of: has_primary_input_or_output CHEBI:32988 +relationship: has_primary_input_or_output CHEBI:32988 [Term] id: GO:0043604 @@ -91238,8 +78244,8 @@ def: "The chemical reactions and pathways resulting in the formation of an amide is_a: GO:0043603 ! amide metabolic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:32988 ! amide -relationship: has_primary_output CHEBI:32988 ! amide +intersection_of: has_primary_output CHEBI:32988 +relationship: has_primary_output CHEBI:32988 [Term] id: GO:0043605 @@ -91250,8 +78256,8 @@ synonym: "cellular amide catabolic process" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0043603 ! amide metabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_output CHEBI:32988 ! amide -relationship: has_primary_output CHEBI:32988 ! amide +intersection_of: has_primary_output CHEBI:32988 +relationship: has_primary_output CHEBI:32988 [Term] id: GO:0043615 @@ -91286,8 +78292,8 @@ synonym: "dicarboxylate metabolism" EXACT [] synonym: "dicarboxylic acid metabolism" EXACT [] is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:35693 ! dicarboxylic acid anion -relationship: has_primary_input_or_output CHEBI:35693 ! dicarboxylic acid anion +intersection_of: has_primary_input_or_output CHEBI:35693 +relationship: has_primary_input_or_output CHEBI:35693 [Term] id: GO:0043649 @@ -91299,11 +78305,11 @@ synonym: "dicarboxylate catabolism" EXACT [] synonym: "dicarboxylic acid breakdown" EXACT [] synonym: "dicarboxylic acid catabolism" EXACT [] synonym: "dicarboxylic acid degradation" EXACT [] +is_a: GO:0009056 ! catabolic process is_a: GO:0043648 ! dicarboxylic acid metabolic process -is_a: GO:0046395 ! carboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:35693 ! dicarboxylic acid anion -relationship: has_primary_input CHEBI:35693 ! dicarboxylic acid anion +intersection_of: has_primary_input CHEBI:35693 +relationship: has_primary_input CHEBI:35693 [Term] id: GO:0043650 @@ -91316,11 +78322,11 @@ synonym: "dicarboxylic acid anabolism" EXACT [] synonym: "dicarboxylic acid biosynthesis" EXACT [] synonym: "dicarboxylic acid formation" EXACT [] synonym: "dicarboxylic acid synthesis" EXACT [] +is_a: GO:0009058 ! biosynthetic process is_a: GO:0043648 ! dicarboxylic acid metabolic process -is_a: GO:0046394 ! carboxylic acid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:35693 ! dicarboxylic acid anion -relationship: has_primary_output CHEBI:35693 ! dicarboxylic acid anion +intersection_of: has_primary_output CHEBI:35693 +relationship: has_primary_output CHEBI:35693 [Term] id: GO:0043679 @@ -91484,10 +78490,10 @@ name: glucan metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues." [GOC:jl] synonym: "glucan metabolism" EXACT [] -is_a: GO:0005976 ! polysaccharide metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:37163 ! glucan -relationship: has_primary_input_or_output CHEBI:37163 ! glucan +intersection_of: has_primary_input_or_output CHEBI:37163 +relationship: has_primary_input_or_output CHEBI:37163 [Term] id: GO:0044057 @@ -91649,6 +78655,7 @@ id: GO:0044237 name: cellular metabolic process namespace: biological_process def: "The chemical reactions and pathways by which individual cells transform chemical substances." [GOC:go_curators] +comment: This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term. subset: gocheck_do_not_annotate synonym: "cellular metabolism" EXACT [] synonym: "intermediary metabolism" RELATED [GOC:mah] @@ -91664,30 +78671,6 @@ subset: goslim_pir synonym: "primary metabolism" EXACT [] is_a: GO:0008152 ! metabolic process -[Term] -id: GO:0044242 -name: cellular lipid catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells." [GOC:jl] -synonym: "cellular lipid breakdown" EXACT [] -synonym: "cellular lipid catabolism" EXACT [] -synonym: "cellular lipid degradation" EXACT [] -is_a: GO:0016042 ! lipid catabolic process -is_a: GO:0044248 ! cellular catabolic process -is_a: GO:0044255 ! cellular lipid metabolic process - -[Term] -id: GO:0044247 -name: cellular polysaccharide catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, as carried out by individual cells." [GOC:jl] -synonym: "cellular polysaccharide breakdown" EXACT [] -synonym: "cellular polysaccharide catabolism" EXACT [] -synonym: "cellular polysaccharide degradation" EXACT [] -is_a: GO:0000272 ! polysaccharide catabolic process -is_a: GO:0044264 ! cellular polysaccharide metabolic process -is_a: GO:0044275 ! cellular carbohydrate catabolic process - [Term] id: GO:0044248 name: cellular catabolic process @@ -91711,16 +78694,6 @@ synonym: "cellular synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0044237 ! cellular metabolic process -[Term] -id: GO:0044255 -name: cellular lipid metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving lipids, as carried out by individual cells." [GOC:jl] -subset: goslim_pir -synonym: "cellular lipid metabolism" EXACT [] -is_a: GO:0006629 ! lipid metabolic process -is_a: GO:0044237 ! cellular metabolic process - [Term] id: GO:0044258 name: intestinal lipid catabolic process @@ -91734,55 +78707,6 @@ intersection_of: GO:0016042 ! lipid catabolic process intersection_of: occurs_in UBERON:0000160 ! intestine relationship: occurs_in UBERON:0000160 ! intestine -[Term] -id: GO:0044260 -name: cellular macromolecule metabolic process -namespace: biological_process -alt_id: GO:0034960 -def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells." [GOC:mah] -synonym: "cellular biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09] -synonym: "cellular macromolecule metabolism" EXACT [] -is_a: GO:0043170 ! macromolecule metabolic process -is_a: GO:0044237 ! cellular metabolic process - -[Term] -id: GO:0044262 -name: cellular carbohydrate metabolic process -namespace: biological_process -alt_id: GO:0006092 -def: "The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells." [GOC:jl] -synonym: "cellular carbohydrate metabolism" EXACT [] -synonym: "main pathways of carbohydrate metabolic process" NARROW [] -synonym: "main pathways of carbohydrate metabolism" NARROW [] -is_a: GO:0005975 ! carbohydrate metabolic process -is_a: GO:0044237 ! cellular metabolic process - -[Term] -id: GO:0044264 -name: cellular polysaccharide metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, as carried out by individual cells." [GOC:jl] -synonym: "cellular glycan metabolic process" EXACT [] -synonym: "cellular glycan metabolism" EXACT [] -synonym: "cellular polysaccharide metabolism" EXACT [] -is_a: GO:0005976 ! polysaccharide metabolic process -is_a: GO:0044260 ! cellular macromolecule metabolic process -is_a: GO:0044262 ! cellular carbohydrate metabolic process - -[Term] -id: GO:0044265 -name: cellular macromolecule catabolic process -namespace: biological_process -alt_id: GO:0034962 -def: "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells." [GOC:jl] -synonym: "cellular biopolymer catabolic process" EXACT [GOC:mtg_chebi_dec09] -synonym: "cellular macromolecule breakdown" EXACT [] -synonym: "cellular macromolecule catabolism" EXACT [] -synonym: "cellular macromolecule degradation" EXACT [] -is_a: GO:0009057 ! macromolecule catabolic process -is_a: GO:0044248 ! cellular catabolic process -is_a: GO:0044260 ! cellular macromolecule metabolic process - [Term] id: GO:0044270 name: cellular nitrogen compound catabolic process @@ -91806,51 +78730,6 @@ synonym: "nitrogen compound synthesis" BROAD [] is_a: GO:0034641 ! cellular nitrogen compound metabolic process is_a: GO:0044249 ! cellular biosynthetic process -[Term] -id: GO:0044272 -name: sulfur compound biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:jl] -synonym: "sulfur biosynthesis" NARROW [] -synonym: "sulfur biosynthetic process" NARROW [] -synonym: "sulfur compound anabolism" EXACT [] -synonym: "sulfur compound biosynthesis" EXACT [] -synonym: "sulfur compound formation" EXACT [] -synonym: "sulfur compound synthesis" EXACT [] -is_a: GO:0006790 ! sulfur compound metabolic process -is_a: GO:0044249 ! cellular biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:26835 ! sulfur molecular entity -relationship: has_primary_output CHEBI:26835 ! sulfur molecular entity - -[Term] -id: GO:0044273 -name: sulfur compound catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:jl] -synonym: "sulfur catabolic process" NARROW [] -synonym: "sulfur catabolism" NARROW [] -synonym: "sulfur compound breakdown" EXACT [] -synonym: "sulfur compound catabolism" EXACT [] -synonym: "sulfur compound degradation" EXACT [] -is_a: GO:0006790 ! sulfur compound metabolic process -is_a: GO:0044248 ! cellular catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:26835 ! sulfur molecular entity -relationship: has_primary_input CHEBI:26835 ! sulfur molecular entity - -[Term] -id: GO:0044275 -name: cellular carbohydrate catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells." [GOC:jl] -synonym: "cellular carbohydrate breakdown" EXACT [] -synonym: "cellular carbohydrate catabolism" EXACT [] -synonym: "cellular carbohydrate degradation" EXACT [] -is_a: GO:0016052 ! carbohydrate catabolic process -is_a: GO:0044248 ! cellular catabolic process -is_a: GO:0044262 ! cellular carbohydrate metabolic process - [Term] id: GO:0044281 name: small molecule metabolic process @@ -92029,18 +78908,6 @@ relationship: results_in_assembly_of GO:0031514 ! motile cilium created_by: krc creation_date: 2015-02-06T17:23:23Z -[Term] -id: GO:0044550 -name: secondary metabolite biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." [GOC:jl] -subset: prokaryote_subset -synonym: "secondary metabolite biosynthesis" EXACT [] -is_a: GO:0009058 ! biosynthetic process -is_a: GO:0019748 ! secondary metabolic process -created_by: jl -creation_date: 2012-03-29T01:55:18Z - [Term] id: GO:0044565 name: dendritic cell proliferation @@ -92135,10 +79002,10 @@ id: GO:0044872 name: lipoprotein localization namespace: biological_process def: "Any process in which a lipoprotein is transported to, or maintained in, a specific location." [GOC:jl] -is_a: GO:0008104 ! protein localization +is_a: GO:0033036 ! macromolecule localization intersection_of: GO:0051179 ! localization -intersection_of: has_primary_input CHEBI:6495 ! lipoprotein -relationship: has_primary_input CHEBI:6495 ! lipoprotein +intersection_of: has_primary_input CHEBI:6495 +relationship: has_primary_input CHEBI:6495 created_by: jl creation_date: 2014-11-25T16:27:06Z @@ -92148,7 +79015,7 @@ name: lipoprotein localization to membrane namespace: biological_process def: "A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane." [GOC:jl] is_a: GO:0044872 ! lipoprotein localization -is_a: GO:0072657 ! protein localization to membrane +is_a: GO:0051668 ! localization within membrane intersection_of: GO:0044872 ! lipoprotein localization intersection_of: has_target_end_location GO:0016020 ! membrane created_by: jl @@ -92204,6 +79071,7 @@ synonym: "negative regulation of nitric oxide formation" EXACT [] synonym: "negative regulation of nitric oxide synthesis" EXACT [] is_a: GO:0031327 ! negative regulation of cellular biosynthetic process is_a: GO:0045428 ! regulation of nitric oxide biosynthetic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process is_a: GO:1904406 ! negative regulation of nitric oxide metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006809 ! nitric oxide biosynthetic process @@ -92404,20 +79272,6 @@ namespace: cellular_component def: "Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell." [ISBN:0716731363] is_a: GO:0005856 ! cytoskeleton -[Term] -id: GO:0045117 -name: azole transmembrane transport -namespace: biological_process -def: "The directed movement of azoles, heterocyclic compounds found in many biologically important substances, across a lipid bilayer, across a membrane." [GOC:go_curators, ISBN:3527307206, Wikipedia:Azole] -synonym: "azole transport" RELATED [] -is_a: GO:0055085 ! transmembrane transport -is_a: GO:0071702 ! organic substance transport -is_a: GO:0071705 ! nitrogen compound transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:68452 ! azole -intersection_of: results_in_transport_across GO:0016020 ! membrane -relationship: has_primary_input CHEBI:68452 ! azole - [Term] id: GO:0045120 name: pronucleus @@ -92475,10 +79329,11 @@ relationship: part_of GO:0007135 ! meiosis II id: GO:0045165 name: cell fate commitment namespace: biological_process -def: "The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [ISBN:0716731185] +def: "The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate." [ISBN:0716731185] comment: Note that this term was 'cell fate determination' but the term name was changed to better match its existing definition and the child term 'cell fate determination; GO:0001709' was also created. is_a: GO:0048869 ! cellular developmental process relationship: part_of GO:0030154 ! cell differentiation +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI [Term] id: GO:0045168 @@ -92525,7 +79380,7 @@ synonym: "protein recruitment" EXACT [] is_a: GO:0008104 ! protein localization is_a: GO:0051234 ! establishment of localization intersection_of: GO:0051234 ! establishment of localization -intersection_of: has_primary_input CHEBI:36080 ! protein +intersection_of: has_primary_input CHEBI:36080 [Term] id: GO:0045190 @@ -92649,6 +79504,7 @@ synonym: "CD4 biosynthesis" EXACT [] synonym: "CD4 formation" EXACT [] synonym: "CD4 synthesis" EXACT [] is_a: GO:0009101 ! glycoprotein biosynthetic process +is_a: GO:0019538 ! protein metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output PR:000001004 ! CD4 molecule relationship: has_primary_output PR:000001004 ! CD4 molecule @@ -92664,6 +79520,7 @@ synonym: "regulation of CD4 biosynthetic process" EXACT [] synonym: "regulation of CD4 formation" EXACT [] synonym: "regulation of CD4 synthesis" EXACT [] is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process +is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045222 ! CD4 biosynthetic process relationship: regulates GO:0045222 ! CD4 biosynthetic process @@ -92685,6 +79542,7 @@ synonym: "up-regulation of CD4 biosynthetic process" EXACT [] synonym: "upregulation of CD4 biosynthetic process" EXACT [] is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process is_a: GO:0045223 ! regulation of CD4 production +is_a: GO:0051247 ! positive regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045222 ! CD4 biosynthetic process relationship: positively_regulates GO:0045222 ! CD4 biosynthetic process @@ -92705,6 +79563,7 @@ synonym: "negative regulation of CD4 formation" EXACT [] synonym: "negative regulation of CD4 synthesis" EXACT [] is_a: GO:0010561 ! negative regulation of glycoprotein biosynthetic process is_a: GO:0045223 ! regulation of CD4 production +is_a: GO:0051248 ! negative regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045222 ! CD4 biosynthetic process relationship: negatively_regulates GO:0045222 ! CD4 biosynthetic process @@ -92816,6 +79675,7 @@ synonym: "regulation of nitric oxide biosynthesis" EXACT [] synonym: "regulation of nitric oxide formation" EXACT [] synonym: "regulation of nitric oxide synthesis" EXACT [] is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process is_a: GO:0080164 ! regulation of nitric oxide metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006809 ! nitric oxide biosynthetic process @@ -92837,6 +79697,7 @@ synonym: "up-regulation of nitric oxide biosynthetic process" EXACT [] synonym: "upregulation of nitric oxide biosynthetic process" EXACT [] is_a: GO:0031328 ! positive regulation of cellular biosynthetic process is_a: GO:0045428 ! regulation of nitric oxide biosynthetic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process is_a: GO:1904407 ! positive regulation of nitric oxide metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006809 ! nitric oxide biosynthetic process @@ -92847,12 +79708,10 @@ id: GO:0045443 name: juvenile hormone secretion namespace: biological_process def: "The regulated release of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis." [GOC:go_curators, ISBN:0198547684] -is_a: GO:0046865 ! terpenoid transport is_a: GO:0060986 ! endocrine hormone secretion -is_a: GO:0140353 ! lipid export from cell intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:24943 ! juvenile hormone -relationship: has_primary_input CHEBI:24943 ! juvenile hormone +intersection_of: has_primary_input CHEBI:24943 +relationship: has_primary_input CHEBI:24943 [Term] id: GO:0045444 @@ -92906,12 +79765,11 @@ name: ecdysteroid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids ubiquitous in insects and other arthropods, in which they initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females." [ISBN:0198506732] synonym: "ecdysteroid metabolism" EXACT [] -is_a: GO:0008202 ! steroid metabolic process is_a: GO:0042180 ! cellular ketone metabolic process is_a: GO:0042445 ! hormone metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:23897 ! ecdysteroid -relationship: has_primary_input_or_output CHEBI:23897 ! ecdysteroid +intersection_of: has_primary_input_or_output CHEBI:23897 +relationship: has_primary_input_or_output CHEBI:23897 relationship: part_of GO:0002165 ! instar larval or pupal development [Term] @@ -92923,13 +79781,12 @@ synonym: "ecdysteroid anabolism" EXACT [] synonym: "ecdysteroid biosynthesis" EXACT [] synonym: "ecdysteroid formation" EXACT [] synonym: "ecdysteroid synthesis" EXACT [] -is_a: GO:0006694 ! steroid biosynthetic process is_a: GO:0042181 ! ketone biosynthetic process is_a: GO:0042446 ! hormone biosynthetic process is_a: GO:0045455 ! ecdysteroid metabolic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:23897 ! ecdysteroid -relationship: has_primary_output CHEBI:23897 ! ecdysteroid +intersection_of: has_primary_output CHEBI:23897 +relationship: has_primary_output CHEBI:23897 [Term] id: GO:0045457 @@ -92938,8 +79795,8 @@ namespace: biological_process def: "The regulated release of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development." [GOC:go_curators] is_a: GO:0035929 ! steroid hormone secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:23897 ! ecdysteroid -relationship: has_primary_input CHEBI:23897 ! ecdysteroid +intersection_of: has_primary_input CHEBI:23897 +relationship: has_primary_input CHEBI:23897 [Term] id: GO:0045463 @@ -94797,27 +81654,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007289 ! spermatid nucleus differentiation relationship: positively_regulates GO:0007289 ! spermatid nucleus differentiation -[Term] -id: GO:0045717 -name: negative regulation of fatty acid biosynthetic process -namespace: biological_process -def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids." [GOC:go_curators] -synonym: "down regulation of fatty acid biosynthetic process" EXACT [] -synonym: "down-regulation of fatty acid biosynthetic process" EXACT [] -synonym: "downregulation of fatty acid biosynthetic process" EXACT [] -synonym: "inhibition of fatty acid biosynthetic process" NARROW [] -synonym: "negative regulation of fatty acid anabolism" EXACT [] -synonym: "negative regulation of fatty acid biosynthesis" EXACT [] -synonym: "negative regulation of fatty acid formation" EXACT [] -synonym: "negative regulation of fatty acid synthesis" EXACT [] -is_a: GO:0031327 ! negative regulation of cellular biosynthetic process -is_a: GO:0042304 ! regulation of fatty acid biosynthetic process -is_a: GO:0045922 ! negative regulation of fatty acid metabolic process -is_a: GO:0051055 ! negative regulation of lipid biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0006633 ! fatty acid biosynthetic process -relationship: negatively_regulates GO:0006633 ! fatty acid biosynthetic process - [Term] id: GO:0045719 name: negative regulation of glycogen biosynthetic process @@ -94832,8 +81668,8 @@ synonym: "negative regulation of glycogen biosynthesis" EXACT [] synonym: "negative regulation of glycogen formation" EXACT [] synonym: "negative regulation of glycogen synthesis" EXACT [] is_a: GO:0005979 ! regulation of glycogen biosynthetic process +is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0070874 ! negative regulation of glycogen metabolic process -is_a: GO:2000113 ! negative regulation of cellular macromolecule biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0005978 ! glycogen biosynthetic process relationship: negatively_regulates GO:0005978 ! glycogen biosynthetic process @@ -94848,9 +81684,8 @@ synonym: "down-regulation of gluconeogenesis" EXACT [] synonym: "downregulation of gluconeogenesis" EXACT [] synonym: "inhibition of gluconeogenesis" NARROW [] is_a: GO:0006111 ! regulation of gluconeogenesis -is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process is_a: GO:0031327 ! negative regulation of cellular biosynthetic process -is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006094 ! gluconeogenesis relationship: negatively_regulates GO:0006094 ! gluconeogenesis @@ -94872,28 +81707,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006094 ! gluconeogenesis relationship: positively_regulates GO:0006094 ! gluconeogenesis -[Term] -id: GO:0045723 -name: positive regulation of fatty acid biosynthetic process -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids." [GOC:go_curators] -synonym: "activation of fatty acid biosynthetic process" NARROW [] -synonym: "positive regulation of fatty acid anabolism" EXACT [] -synonym: "positive regulation of fatty acid biosynthesis" EXACT [] -synonym: "positive regulation of fatty acid formation" EXACT [] -synonym: "positive regulation of fatty acid synthesis" EXACT [] -synonym: "stimulation of fatty acid biosynthetic process" NARROW [] -synonym: "up regulation of fatty acid biosynthetic process" EXACT [] -synonym: "up-regulation of fatty acid biosynthetic process" EXACT [] -synonym: "upregulation of fatty acid biosynthetic process" EXACT [] -is_a: GO:0031328 ! positive regulation of cellular biosynthetic process -is_a: GO:0042304 ! regulation of fatty acid biosynthetic process -is_a: GO:0045923 ! positive regulation of fatty acid metabolic process -is_a: GO:0046889 ! positive regulation of lipid biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0006633 ! fatty acid biosynthetic process -relationship: positively_regulates GO:0006633 ! fatty acid biosynthetic process - [Term] id: GO:0045724 name: positive regulation of cilium assembly @@ -94954,8 +81767,6 @@ synonym: "upregulation of protein biosynthetic process" EXACT [] is_a: GO:0006417 ! regulation of translation is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0010628 ! positive regulation of gene expression -is_a: GO:0031328 ! positive regulation of cellular biosynthetic process -is_a: GO:0034250 ! positive regulation of amide metabolic process is_a: GO:0051247 ! positive regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006412 ! translation @@ -95032,36 +81843,6 @@ intersection_of: positively_regulates GO:0030163 ! protein catabolic process relationship: positively_regulates GO:0030163 ! protein catabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI -[Term] -id: GO:0045733 -name: acetate catabolic process -namespace: biological_process -alt_id: GO:0019663 -def: "The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." [GOC:go_curators] -synonym: "acetate breakdown" EXACT [] -synonym: "acetate catabolism" EXACT [] -synonym: "acetate degradation" EXACT [] -synonym: "homoacetate catabolic process" RELATED [] -is_a: GO:0006083 ! acetate metabolic process -is_a: GO:0072329 ! monocarboxylic acid catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:30089 ! acetate -relationship: has_primary_input CHEBI:30089 ! acetate - -[Term] -id: GO:0045734 -name: regulation of acetate catabolic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." [GOC:go_curators] -synonym: "regulation of acetate breakdown" EXACT [] -synonym: "regulation of acetate catabolism" EXACT [] -synonym: "regulation of acetate degradation" EXACT [] -is_a: GO:0010565 ! regulation of cellular ketone metabolic process -is_a: GO:0031329 ! regulation of cellular catabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0045733 ! acetate catabolic process -relationship: regulates GO:0045733 ! acetate catabolic process - [Term] id: GO:0045744 name: negative regulation of G protein-coupled receptor signaling pathway @@ -95108,45 +81889,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007186 ! G protein-coupled receptor signaling pathway relationship: positively_regulates GO:0007186 ! G protein-coupled receptor signaling pathway -[Term] -id: GO:0045753 -name: negative regulation of acetate catabolic process -namespace: biological_process -def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] -synonym: "down regulation of acetate catabolic process" EXACT [] -synonym: "down-regulation of acetate catabolic process" EXACT [] -synonym: "downregulation of acetate catabolic process" EXACT [] -synonym: "inhibition of acetate catabolic process" NARROW [] -synonym: "negative regulation of acetate breakdown" EXACT [] -synonym: "negative regulation of acetate catabolism" EXACT [] -synonym: "negative regulation of acetate degradation" EXACT [] -is_a: GO:0031330 ! negative regulation of cellular catabolic process -is_a: GO:0045734 ! regulation of acetate catabolic process -is_a: GO:0062014 ! negative regulation of small molecule metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0045733 ! acetate catabolic process -relationship: negatively_regulates GO:0045733 ! acetate catabolic process - -[Term] -id: GO:0045754 -name: positive regulation of acetate catabolic process -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] -synonym: "activation of acetate catabolic process" NARROW [] -synonym: "positive regulation of acetate breakdown" EXACT [] -synonym: "positive regulation of acetate catabolism" EXACT [] -synonym: "positive regulation of acetate degradation" EXACT [] -synonym: "stimulation of acetate catabolic process" NARROW [] -synonym: "up regulation of acetate catabolic process" EXACT [] -synonym: "up-regulation of acetate catabolic process" EXACT [] -synonym: "upregulation of acetate catabolic process" EXACT [] -is_a: GO:0031331 ! positive regulation of cellular catabolic process -is_a: GO:0045734 ! regulation of acetate catabolic process -is_a: GO:0062013 ! positive regulation of small molecule metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0045733 ! acetate catabolic process -relationship: positively_regulates GO:0045733 ! acetate catabolic process - [Term] id: GO:0045759 name: negative regulation of action potential @@ -95191,6 +81933,7 @@ synonym: "negative regulation of amino acid metabolism" EXACT [] is_a: GO:0006521 ! regulation of cellular amino acid metabolic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0033239 ! negative regulation of amine metabolic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process is_a: GO:0062014 ! negative regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006520 ! amino acid metabolic process @@ -95211,6 +81954,7 @@ synonym: "upregulation of amino acid metabolic process" EXACT [] is_a: GO:0006521 ! regulation of cellular amino acid metabolic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0033240 ! positive regulation of amine metabolic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process is_a: GO:0062013 ! positive regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006520 ! amino acid metabolic process @@ -95498,41 +82242,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045087 ! innate immune response relationship: negatively_regulates GO:0045087 ! innate immune response -[Term] -id: GO:0045827 -name: negative regulation of isoprenoid metabolic process -namespace: biological_process -def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid." [GOC:go_curators] -synonym: "down regulation of isoprenoid metabolic process" EXACT [] -synonym: "down-regulation of isoprenoid metabolic process" EXACT [] -synonym: "downregulation of isoprenoid metabolic process" EXACT [] -synonym: "inhibition of isoprenoid metabolic process" NARROW [] -synonym: "negative regulation of isoprenoid metabolism" EXACT [] -is_a: GO:0019747 ! regulation of isoprenoid metabolic process -is_a: GO:0031324 ! negative regulation of cellular metabolic process -is_a: GO:0045833 ! negative regulation of lipid metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0006720 ! isoprenoid metabolic process -relationship: negatively_regulates GO:0006720 ! isoprenoid metabolic process - -[Term] -id: GO:0045828 -name: positive regulation of isoprenoid metabolic process -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid." [GOC:go_curators] -synonym: "activation of isoprenoid metabolic process" NARROW [] -synonym: "positive regulation of isoprenoid metabolism" EXACT [] -synonym: "stimulation of isoprenoid metabolic process" NARROW [] -synonym: "up regulation of isoprenoid metabolic process" EXACT [] -synonym: "up-regulation of isoprenoid metabolic process" EXACT [] -synonym: "upregulation of isoprenoid metabolic process" EXACT [] -is_a: GO:0019747 ! regulation of isoprenoid metabolic process -is_a: GO:0031325 ! positive regulation of cellular metabolic process -is_a: GO:0045834 ! positive regulation of lipid metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0006720 ! isoprenoid metabolic process -relationship: positively_regulates GO:0006720 ! isoprenoid metabolic process - [Term] id: GO:0045829 name: negative regulation of isotype switching @@ -96023,43 +82732,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006887 ! exocytosis relationship: positively_regulates GO:0006887 ! exocytosis -[Term] -id: GO:0045922 -name: negative regulation of fatty acid metabolic process -namespace: biological_process -def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids." [GOC:go_curators] -synonym: "down regulation of fatty acid metabolic process" EXACT [] -synonym: "down-regulation of fatty acid metabolic process" EXACT [] -synonym: "downregulation of fatty acid metabolic process" EXACT [] -synonym: "inhibition of fatty acid metabolic process" NARROW [] -synonym: "negative regulation of fatty acid metabolism" EXACT [] -is_a: GO:0019217 ! regulation of fatty acid metabolic process -is_a: GO:0031324 ! negative regulation of cellular metabolic process -is_a: GO:0045833 ! negative regulation of lipid metabolic process -is_a: GO:0062014 ! negative regulation of small molecule metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0006631 ! fatty acid metabolic process -relationship: negatively_regulates GO:0006631 ! fatty acid metabolic process - -[Term] -id: GO:0045923 -name: positive regulation of fatty acid metabolic process -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids." [GOC:go_curators] -synonym: "activation of fatty acid metabolic process" NARROW [] -synonym: "positive regulation of fatty acid metabolism" EXACT [] -synonym: "stimulation of fatty acid metabolic process" NARROW [] -synonym: "up regulation of fatty acid metabolic process" EXACT [] -synonym: "up-regulation of fatty acid metabolic process" EXACT [] -synonym: "upregulation of fatty acid metabolic process" EXACT [] -is_a: GO:0019217 ! regulation of fatty acid metabolic process -is_a: GO:0031325 ! positive regulation of cellular metabolic process -is_a: GO:0045834 ! positive regulation of lipid metabolic process -is_a: GO:0062013 ! positive regulation of small molecule metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0006631 ! fatty acid metabolic process -relationship: positively_regulates GO:0006631 ! fatty acid metabolic process - [Term] id: GO:0045926 name: negative regulation of growth @@ -96103,7 +82775,6 @@ synonym: "inhibition of juvenile hormone metabolic process" NARROW [] synonym: "negative regulation of juvenile hormone metabolism" EXACT [] is_a: GO:0007556 ! regulation of juvenile hormone metabolic process is_a: GO:0032351 ! negative regulation of hormone metabolic process -is_a: GO:0045827 ! negative regulation of isoprenoid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006716 ! juvenile hormone metabolic process relationship: negatively_regulates GO:0006716 ! juvenile hormone metabolic process @@ -96121,7 +82792,6 @@ synonym: "up-regulation of juvenile hormone metabolic process" EXACT [] synonym: "upregulation of juvenile hormone metabolic process" EXACT [] is_a: GO:0007556 ! regulation of juvenile hormone metabolic process is_a: GO:0032352 ! positive regulation of hormone metabolic process -is_a: GO:0045828 ! positive regulation of isoprenoid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006716 ! juvenile hormone metabolic process relationship: positively_regulates GO:0006716 ! juvenile hormone metabolic process @@ -96239,7 +82909,7 @@ synonym: "down-regulation of phosphate metabolic process" EXACT [] synonym: "downregulation of phosphate metabolic process" EXACT [] synonym: "inhibition of phosphate metabolic process" NARROW [] synonym: "negative regulation of phosphate metabolism" EXACT [] -is_a: GO:0010563 ! negative regulation of phosphorus metabolic process +is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0019220 ! regulation of phosphate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006796 ! phosphate-containing compound metabolic process @@ -96256,7 +82926,7 @@ synonym: "stimulation of phosphate metabolic process" NARROW [] synonym: "up regulation of phosphate metabolic process" EXACT [] synonym: "up-regulation of phosphate metabolic process" EXACT [] synonym: "upregulation of phosphate metabolic process" EXACT [] -is_a: GO:0010562 ! positive regulation of phosphorus metabolic process +is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0019220 ! regulation of phosphate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006796 ! phosphate-containing compound metabolic process @@ -96306,6 +82976,7 @@ synonym: "downregulation of translational initiation" EXACT [] synonym: "inhibition of translational initiation" NARROW [] is_a: GO:0006446 ! regulation of translational initiation is_a: GO:0017148 ! negative regulation of translation +is_a: GO:0031324 ! negative regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006413 ! translational initiation relationship: negatively_regulates GO:0006413 ! translational initiation @@ -96321,6 +82992,7 @@ synonym: "up regulation of translational initiation" EXACT [] synonym: "up-regulation of translational initiation" EXACT [] synonym: "upregulation of translational initiation" EXACT [] is_a: GO:0006446 ! regulation of translational initiation +is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0045727 ! positive regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006413 ! translational initiation @@ -96335,8 +83007,7 @@ synonym: "regulation of juvenile hormone breakdown" EXACT [] synonym: "regulation of juvenile hormone catabolism" EXACT [] synonym: "regulation of juvenile hormone degradation" EXACT [] is_a: GO:0007556 ! regulation of juvenile hormone metabolic process -is_a: GO:0031329 ! regulation of cellular catabolic process -is_a: GO:0050994 ! regulation of lipid catabolic process +is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006719 ! juvenile hormone catabolic process relationship: regulates GO:0006719 ! juvenile hormone catabolic process @@ -96398,8 +83069,8 @@ synonym: "down-regulation of dopamine metabolic process" EXACT [] synonym: "downregulation of dopamine metabolic process" EXACT [] synonym: "inhibition of dopamine metabolic process" NARROW [] synonym: "negative regulation of dopamine metabolism" EXACT [] +is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0042053 ! regulation of dopamine metabolic process -is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042417 ! dopamine metabolic process relationship: negatively_regulates GO:0042417 ! dopamine metabolic process @@ -96415,8 +83086,8 @@ synonym: "stimulation of dopamine metabolic process" NARROW [] synonym: "up regulation of dopamine metabolic process" EXACT [] synonym: "up-regulation of dopamine metabolic process" EXACT [] synonym: "upregulation of dopamine metabolic process" EXACT [] +is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0042053 ! regulation of dopamine metabolic process -is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042417 ! dopamine metabolic process relationship: positively_regulates GO:0042417 ! dopamine metabolic process @@ -96434,7 +83105,6 @@ synonym: "negative regulation of ecdysteroid metabolism" EXACT [] is_a: GO:0007553 ! regulation of ecdysteroid metabolic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0032351 ! negative regulation of hormone metabolic process -is_a: GO:0045939 ! negative regulation of steroid metabolic process is_a: GO:0062014 ! negative regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045455 ! ecdysteroid metabolic process @@ -96454,7 +83124,6 @@ synonym: "upregulation of ecdysteroid metabolic process" EXACT [] is_a: GO:0007553 ! regulation of ecdysteroid metabolic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0032352 ! positive regulation of hormone metabolic process -is_a: GO:0045940 ! positive regulation of steroid metabolic process is_a: GO:0062013 ! positive regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045455 ! ecdysteroid metabolic process @@ -96476,7 +83145,6 @@ synonym: "negative regulation of juvenile hormone synthesis" EXACT [] is_a: GO:0007557 ! regulation of juvenile hormone biosynthetic process is_a: GO:0032353 ! negative regulation of hormone biosynthetic process is_a: GO:0045928 ! negative regulation of juvenile hormone metabolic process -is_a: GO:0051055 ! negative regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006718 ! juvenile hormone biosynthetic process relationship: negatively_regulates GO:0006718 ! juvenile hormone biosynthetic process @@ -96498,7 +83166,6 @@ synonym: "upregulation of juvenile hormone biosynthetic process" EXACT [] is_a: GO:0007557 ! regulation of juvenile hormone biosynthetic process is_a: GO:0045929 ! positive regulation of juvenile hormone metabolic process is_a: GO:0046886 ! positive regulation of hormone biosynthetic process -is_a: GO:0046889 ! positive regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006718 ! juvenile hormone biosynthetic process relationship: positively_regulates GO:0006718 ! juvenile hormone biosynthetic process @@ -96515,10 +83182,9 @@ synonym: "inhibition of juvenile hormone catabolic process" NARROW [] synonym: "negative regulation of juvenile hormone breakdown" EXACT [] synonym: "negative regulation of juvenile hormone catabolism" EXACT [] synonym: "negative regulation of juvenile hormone degradation" EXACT [] -is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0045928 ! negative regulation of juvenile hormone metabolic process is_a: GO:0045952 ! regulation of juvenile hormone catabolic process -is_a: GO:0050995 ! negative regulation of lipid catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006719 ! juvenile hormone catabolic process relationship: negatively_regulates GO:0006719 ! juvenile hormone catabolic process @@ -96536,10 +83202,9 @@ synonym: "stimulation of juvenile hormone catabolic process" NARROW [] synonym: "up regulation of juvenile hormone catabolic process" EXACT [] synonym: "up-regulation of juvenile hormone catabolic process" EXACT [] synonym: "upregulation of juvenile hormone catabolic process" EXACT [] -is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0045929 ! positive regulation of juvenile hormone metabolic process is_a: GO:0045952 ! regulation of juvenile hormone catabolic process -is_a: GO:0050996 ! positive regulation of lipid catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006719 ! juvenile hormone catabolic process relationship: positively_regulates GO:0006719 ! juvenile hormone catabolic process @@ -96554,7 +83219,6 @@ synonym: "down-regulation of juvenile hormone secretion" EXACT [] synonym: "downregulation of juvenile hormone secretion" EXACT [] synonym: "inhibition of juvenile hormone secretion" NARROW [] is_a: GO:0007558 ! regulation of juvenile hormone secretion -is_a: GO:0032369 ! negative regulation of lipid transport is_a: GO:0046888 ! negative regulation of hormone secretion is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation @@ -96572,7 +83236,6 @@ synonym: "up regulation of juvenile hormone secretion" EXACT [] synonym: "up-regulation of juvenile hormone secretion" EXACT [] synonym: "upregulation of juvenile hormone secretion" EXACT [] is_a: GO:0007558 ! regulation of juvenile hormone secretion -is_a: GO:0032370 ! positive regulation of lipid transport is_a: GO:0046887 ! positive regulation of hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045443 ! juvenile hormone secretion @@ -96772,70 +83435,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001777 ! T cell homeostatic proliferation relationship: negatively_regulates GO:0001777 ! T cell homeostatic proliferation -[Term] -id: GO:0046112 -name: nucleobase biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." [GOC:ai] -synonym: "nucleobase anabolism" EXACT [] -synonym: "nucleobase biosynthesis" EXACT [] -synonym: "nucleobase formation" EXACT [] -synonym: "nucleobase synthesis" EXACT [] -is_a: GO:0009112 ! nucleobase metabolic process -is_a: GO:0018130 ! heterocycle biosynthetic process -is_a: GO:1901362 ! organic cyclic compound biosynthetic process -is_a: GO:1901566 ! organonitrogen compound biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:18282 ! nucleobase -relationship: has_primary_output CHEBI:18282 ! nucleobase - -[Term] -id: GO:0046113 -name: nucleobase catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." [GOC:ai] -synonym: "nucleobase breakdown" EXACT [] -synonym: "nucleobase catabolism" EXACT [] -synonym: "nucleobase degradation" EXACT [] -is_a: GO:0009112 ! nucleobase metabolic process -is_a: GO:0046700 ! heterocycle catabolic process -is_a: GO:1901361 ! organic cyclic compound catabolic process -is_a: GO:1901565 ! organonitrogen compound catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:18282 ! nucleobase -relationship: has_primary_input CHEBI:18282 ! nucleobase - -[Term] -id: GO:0046164 -name: alcohol catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom." [GOC:ai] -synonym: "alcohol breakdown" EXACT [] -synonym: "alcohol catabolism" EXACT [] -synonym: "alcohol degradation" EXACT [] -is_a: GO:0006066 ! alcohol metabolic process -is_a: GO:0044282 ! small molecule catabolic process -is_a: GO:1901616 ! organic hydroxy compound catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:30879 ! alcohol -relationship: has_primary_input CHEBI:30879 ! alcohol - -[Term] -id: GO:0046165 -name: alcohol biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom." [GOC:ai] -synonym: "alcohol anabolism" EXACT [] -synonym: "alcohol biosynthesis" EXACT [] -synonym: "alcohol formation" EXACT [] -synonym: "alcohol synthesis" EXACT [] -is_a: GO:0006066 ! alcohol metabolic process -is_a: GO:0044283 ! small molecule biosynthetic process -is_a: GO:1901617 ! organic hydroxy compound biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:30879 ! alcohol -relationship: has_primary_output CHEBI:30879 ! alcohol - [Term] id: GO:0046184 name: aldehyde biosynthetic process @@ -96849,8 +83448,8 @@ is_a: GO:0006081 ! cellular aldehyde metabolic process is_a: GO:0044249 ! cellular biosynthetic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:17478 ! aldehyde -relationship: has_primary_output CHEBI:17478 ! aldehyde +intersection_of: has_primary_output CHEBI:17478 +relationship: has_primary_output CHEBI:17478 [Term] id: GO:0046185 @@ -96862,10 +83461,9 @@ synonym: "aldehyde catabolism" EXACT [] synonym: "aldehyde degradation" EXACT [] is_a: GO:0006081 ! cellular aldehyde metabolic process is_a: GO:0044248 ! cellular catabolic process -is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:17478 ! aldehyde -relationship: has_primary_input CHEBI:17478 ! aldehyde +intersection_of: has_primary_input CHEBI:17478 +relationship: has_primary_input CHEBI:17478 [Term] id: GO:0046189 @@ -96876,13 +83474,11 @@ synonym: "phenol-containing compound anabolism" EXACT [] synonym: "phenol-containing compound biosynthesis" EXACT [] synonym: "phenol-containing compound formation" EXACT [] synonym: "phenol-containing compound synthesis" EXACT [] +is_a: GO:0009058 ! biosynthetic process is_a: GO:0018958 ! phenol-containing compound metabolic process -is_a: GO:0019438 ! aromatic compound biosynthetic process -is_a: GO:1901362 ! organic cyclic compound biosynthetic process -is_a: GO:1901617 ! organic hydroxy compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:33853 ! phenols -relationship: has_primary_output CHEBI:33853 ! phenols +intersection_of: has_primary_output CHEBI:33853 +relationship: has_primary_output CHEBI:33853 [Term] id: GO:0046209 @@ -96890,10 +83486,10 @@ name: nitric oxide metabolic process namespace: biological_process def: "The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water." [GOC:ai] synonym: "nitric oxide metabolism" EXACT [] -is_a: GO:2001057 ! reactive nitrogen species metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:16480 ! nitric oxide -relationship: has_primary_input_or_output CHEBI:16480 ! nitric oxide +intersection_of: has_primary_input_or_output CHEBI:16480 +relationship: has_primary_input_or_output CHEBI:16480 [Term] id: GO:0046210 @@ -96906,55 +83502,8 @@ synonym: "nitric oxide degradation" EXACT [] is_a: GO:0044270 ! cellular nitrogen compound catabolic process is_a: GO:0046209 ! nitric oxide metabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:16480 ! nitric oxide -relationship: has_primary_input CHEBI:16480 ! nitric oxide - -[Term] -id: GO:0046219 -name: indolalkylamine biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." [GOC:curators] -synonym: "indolalkylamine anabolism" EXACT [] -synonym: "indolalkylamine biosynthesis" EXACT [] -synonym: "indolalkylamine formation" EXACT [] -synonym: "indolalkylamine synthesis" EXACT [] -is_a: GO:0006586 ! indolalkylamine metabolic process -is_a: GO:0042401 ! biogenic amine biosynthetic process -is_a: GO:0042435 ! indole-containing compound biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:38631 ! aminoalkylindole -relationship: has_primary_output CHEBI:38631 ! aminoalkylindole - -[Term] -id: GO:0046246 -name: terpene biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of terpenes, any of a large group of hydrocarbons made up of isoprene units." [GOC:ai] -synonym: "terpene anabolism" EXACT [] -synonym: "terpene biosynthesis" EXACT [] -synonym: "terpene formation" EXACT [] -synonym: "terpene synthesis" EXACT [] -is_a: GO:0008299 ! isoprenoid biosynthetic process -is_a: GO:0042214 ! terpene metabolic process -is_a: GO:0120251 ! hydrocarbon biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:35186 ! terpene -relationship: has_primary_output CHEBI:35186 ! terpene - -[Term] -id: GO:0046247 -name: terpene catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units." [GOC:ai] -synonym: "terpene breakdown" EXACT [] -synonym: "terpene catabolism" EXACT [] -synonym: "terpene degradation" EXACT [] -is_a: GO:0008300 ! isoprenoid catabolic process -is_a: GO:0042214 ! terpene metabolic process -is_a: GO:0120253 ! hydrocarbon catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:35186 ! terpene -relationship: has_primary_input CHEBI:35186 ! terpene +intersection_of: has_primary_input CHEBI:16480 +relationship: has_primary_input CHEBI:16480 [Term] id: GO:0046344 @@ -96964,84 +83513,12 @@ def: "The chemical reactions and pathways resulting in the breakdown of ecdyster synonym: "ecdysteroid breakdown" EXACT [] synonym: "ecdysteroid catabolism" EXACT [] synonym: "ecdysteroid degradation" EXACT [] -is_a: GO:0006706 ! steroid catabolic process is_a: GO:0042182 ! ketone catabolic process is_a: GO:0042447 ! hormone catabolic process is_a: GO:0045455 ! ecdysteroid metabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:23897 ! ecdysteroid -relationship: has_primary_input CHEBI:23897 ! ecdysteroid - -[Term] -id: GO:0046358 -name: butyrate biosynthetic process -namespace: biological_process -alt_id: GO:0043439 -def: "The chemical reactions and pathways resulting in the formation of butyrate, the anion of butyric acid." [ISBN:0198506732] -synonym: "butanoic acid anabolism" EXACT [] -synonym: "butanoic acid biosynthesis" EXACT [] -synonym: "butanoic acid biosynthetic process" EXACT [] -synonym: "butanoic acid formation" EXACT [] -synonym: "butanoic acid synthesis" EXACT [] -synonym: "butyrate anabolism" EXACT [] -synonym: "butyrate biosynthesis" EXACT [] -synonym: "butyrate formation" EXACT [] -synonym: "butyrate synthesis" EXACT [] -is_a: GO:0019605 ! butyrate metabolic process -is_a: GO:0051790 ! short-chain fatty acid biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:17968 ! butyrate -relationship: has_primary_output CHEBI:17968 ! butyrate - -[Term] -id: GO:0046359 -name: butyrate catabolic process -namespace: biological_process -alt_id: GO:0043440 -def: "The chemical reactions and pathways resulting in the breakdown of butyrate, the anion of butyric acid." [ISBN:0198506732] -synonym: "butanoic acid breakdown" EXACT [] -synonym: "butanoic acid catabolic process" EXACT [] -synonym: "butanoic acid catabolism" EXACT [] -synonym: "butanoic acid degradation" EXACT [] -synonym: "butyrate breakdown" EXACT [] -synonym: "butyrate catabolism" EXACT [] -synonym: "butyrate degradation" EXACT [] -is_a: GO:0019605 ! butyrate metabolic process -is_a: GO:0019626 ! short-chain fatty acid catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:17968 ! butyrate -relationship: has_primary_input CHEBI:17968 ! butyrate - -[Term] -id: GO:0046364 -name: monosaccharide biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." [ISBN:0198506732] -synonym: "monosaccharide anabolism" EXACT [] -synonym: "monosaccharide biosynthesis" EXACT [] -synonym: "monosaccharide formation" EXACT [] -synonym: "monosaccharide synthesis" EXACT [] -is_a: GO:0005996 ! monosaccharide metabolic process -is_a: GO:0016051 ! carbohydrate biosynthetic process -is_a: GO:0044283 ! small molecule biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:35381 ! monosaccharide -relationship: has_primary_output CHEBI:35381 ! monosaccharide - -[Term] -id: GO:0046365 -name: monosaccharide catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." [ISBN:0198506732] -synonym: "monosaccharide breakdown" EXACT [] -synonym: "monosaccharide catabolism" EXACT [] -synonym: "monosaccharide degradation" EXACT [] -is_a: GO:0005996 ! monosaccharide metabolic process -is_a: GO:0016052 ! carbohydrate catabolic process -is_a: GO:0044282 ! small molecule catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:35381 ! monosaccharide -relationship: has_primary_input CHEBI:35381 ! monosaccharide +intersection_of: has_primary_input CHEBI:23897 +relationship: has_primary_input CHEBI:23897 [Term] id: GO:0046394 @@ -97055,8 +83532,8 @@ synonym: "carboxylic acid synthesis" EXACT [] is_a: GO:0016053 ! organic acid biosynthetic process is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:29067 ! carboxylic acid anion -relationship: has_primary_output CHEBI:29067 ! carboxylic acid anion +intersection_of: has_primary_output CHEBI:29067 +relationship: has_primary_output CHEBI:29067 [Term] id: GO:0046395 @@ -97069,44 +83546,8 @@ synonym: "carboxylic acid degradation" EXACT [] is_a: GO:0016054 ! organic acid catabolic process is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:29067 ! carboxylic acid anion -relationship: has_primary_input CHEBI:29067 ! carboxylic acid anion - -[Term] -id: GO:0046459 -name: short-chain fatty acid metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving fatty acids with a chain length of less than C6." [Wikipedia:Fatty_acid_metabolism] -synonym: "short-chain fatty acid metabolism" EXACT [] -is_a: GO:0006631 ! fatty acid metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:58951 ! short-chain fatty acid anion -relationship: has_primary_input_or_output CHEBI:58951 ! short-chain fatty acid anion - -[Term] -id: GO:0046466 -name: membrane lipid catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane." [GOC:ai] -synonym: "membrane lipid breakdown" EXACT [] -synonym: "membrane lipid catabolism" EXACT [] -synonym: "membrane lipid degradation" EXACT [] -synonym: "membrane lipid peroxidation" BROAD [GOC:tb] -is_a: GO:0006643 ! membrane lipid metabolic process -is_a: GO:0044242 ! cellular lipid catabolic process - -[Term] -id: GO:0046467 -name: membrane lipid biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane." [GOC:ai] -synonym: "membrane lipid anabolism" EXACT [] -synonym: "membrane lipid biosynthesis" EXACT [] -synonym: "membrane lipid formation" EXACT [] -synonym: "membrane lipid synthesis" EXACT [] -is_a: GO:0006643 ! membrane lipid metabolic process -is_a: GO:0008610 ! lipid biosynthetic process -is_a: GO:0044249 ! cellular biosynthetic process +intersection_of: has_primary_input CHEBI:29067 +relationship: has_primary_input CHEBI:29067 [Term] id: GO:0046479 @@ -97117,11 +83558,10 @@ synonym: "glycosphingolipid breakdown" EXACT [] synonym: "glycosphingolipid catabolism" EXACT [] synonym: "glycosphingolipid degradation" EXACT [] is_a: GO:0006687 ! glycosphingolipid metabolic process -is_a: GO:0019377 ! glycolipid catabolic process -is_a: GO:0030149 ! sphingolipid catabolic process +is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:24402 ! glycosphingolipid -relationship: has_primary_input CHEBI:24402 ! glycosphingolipid +intersection_of: has_primary_input CHEBI:24402 +relationship: has_primary_input CHEBI:24402 [Term] id: GO:0046483 @@ -97132,8 +83572,8 @@ subset: goslim_pir synonym: "heterocycle metabolism" EXACT [] is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:5686 ! heterocyclic compound -relationship: has_primary_input_or_output CHEBI:5686 ! heterocyclic compound +intersection_of: has_primary_input_or_output CHEBI:5686 +relationship: has_primary_input_or_output CHEBI:5686 [Term] id: GO:0046530 @@ -97288,27 +83728,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035265 ! organ growth relationship: positively_regulates GO:0035265 ! organ growth -[Term] -id: GO:0046624 -name: sphingolipid transporter activity -namespace: molecular_function -def: "Enables the directed movement of sphingolipids into, out of or within a cell, or between cells. Sphingolipids are a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [GOC:ai, ISBN:0198506732] -xref: Reactome:R-HSA-9695890 "SPNS2 transports S1P from cytosol to extracellular region" -is_a: GO:0005319 ! lipid transporter activity -intersection_of: GO:0005215 ! transporter activity -intersection_of: has_primary_input CHEBI:26739 ! sphingolipid -relationship: has_primary_input CHEBI:26739 ! sphingolipid - -[Term] -id: GO:0046625 -name: sphingolipid binding -namespace: molecular_function -def: "Binding to a sphingolipid, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [ISBN:0198506732] -is_a: GO:0008289 ! lipid binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:26739 ! sphingolipid -relationship: has_input CHEBI:26739 ! sphingolipid - [Term] id: GO:0046626 name: regulation of insulin receptor signaling pathway @@ -97861,20 +84280,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030073 ! insulin secretion relationship: negatively_regulates GO:0030073 ! insulin secretion -[Term] -id: GO:0046681 -name: response to carbamate -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase." [ISBN:0721662544] -synonym: "carbamate resistance" RELATED [] -synonym: "carbamate susceptibility/resistance" RELATED [] -is_a: GO:0010243 ! response to organonitrogen compound -is_a: GO:0017085 ! response to insecticide -is_a: GO:1901700 ! response to oxygen-containing compound -intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:13941 ! carbamate -relationship: has_input CHEBI:13941 ! carbamate - [Term] id: GO:0046700 name: heterocycle catabolic process @@ -97886,8 +84291,8 @@ synonym: "heterocycle degradation" EXACT [] is_a: GO:0044248 ! cellular catabolic process is_a: GO:0046483 ! heterocycle metabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:5686 ! heterocyclic compound -relationship: has_primary_input CHEBI:5686 ! heterocyclic compound +intersection_of: has_primary_input CHEBI:5686 +relationship: has_primary_input CHEBI:5686 [Term] id: GO:0046716 @@ -97910,17 +84315,6 @@ namespace: biological_process def: "The controlled release of acid by a cell or a tissue." [GOC:ai] is_a: GO:0046903 ! secretion -[Term] -id: GO:0046721 -name: formic acid secretion -namespace: biological_process -def: "The controlled release of formic acid, HCOOH, by a cell or a tissue." [GOC:ai] -synonym: "formate secretion" EXACT [] -is_a: GO:0015724 ! formate transport -is_a: GO:0046717 ! acid secretion -intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:15740 ! formate - [Term] id: GO:0046785 name: microtubule polymerization @@ -97936,17 +84330,6 @@ intersection_of: results_in_assembly_of GO:0005874 ! microtubule relationship: results_in_assembly_of GO:0005874 ! microtubule relationship: starts_with GO:0007020 ! microtubule nucleation -[Term] -id: GO:0046836 -name: glycolipid transport -namespace: biological_process -def: "The directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] -is_a: GO:0006869 ! lipid transport -is_a: GO:1901264 ! carbohydrate derivative transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:33563 ! glycolipid -relationship: has_primary_input CHEBI:33563 ! glycolipid - [Term] id: GO:0046848 name: hydroxyapatite binding @@ -97955,8 +84338,8 @@ def: "Binding to hydroxyapatite, the calcium phosphate mineral of formula Ca10(P synonym: "hydroxylapatite binding" EXACT [GOC:vk] is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:52255 ! hydroxylapatite -relationship: has_input CHEBI:52255 ! hydroxylapatite +intersection_of: has_input CHEBI:52255 +relationship: has_input CHEBI:52255 [Term] id: GO:0046849 @@ -98008,61 +84391,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046849 ! bone remodeling relationship: positively_regulates GO:0046849 ! bone remodeling -[Term] -id: GO:0046864 -name: isoprenoid transport -namespace: biological_process -def: "The directed movement of isoprenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Isoprenoids comprise a group of compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." [GOC:ai] -subset: goslim_pir -is_a: GO:0006869 ! lipid transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:24913 ! isoprenoid -relationship: has_primary_input CHEBI:24913 ! isoprenoid - -[Term] -id: GO:0046865 -name: terpenoid transport -namespace: biological_process -def: "The directed movement of terpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Terpenoids are a class of compounds characterized by an isoprenoid chemical structure and include derivatives with various functional groups." [GOC:ai] -is_a: GO:0046864 ! isoprenoid transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:26873 ! terpenoid -relationship: has_primary_input CHEBI:26873 ! terpenoid - -[Term] -id: GO:0046872 -name: metal ion binding -namespace: molecular_function -def: "Binding to a metal ion." [GOC:ai] -subset: goslim_agr -subset: goslim_drosophila -subset: goslim_flybase_ribbon -subset: goslim_metagenomics -synonym: "heavy metal binding" NARROW [] -synonym: "metal binding" EXACT [] -is_a: GO:0043169 ! cation binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:25213 ! metal cation -relationship: has_input CHEBI:25213 ! metal cation - -[Term] -id: GO:0046873 -name: metal ion transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of metal ions from one side of a membrane to the other." [GOC:ai] -synonym: "heavy metal ion porter activity" NARROW [] -synonym: "heavy metal ion transporter activity" NARROW [] -synonym: "heavy metal ion:hydrogen symporter activity" NARROW [] -synonym: "heavy metal-exporting ATPase activity" NARROW [] -synonym: "high affinity metal ion uptake transporter activity" NARROW [] -synonym: "low affinity metal ion uptake transporter activity" NARROW [] -is_a: GO:0008324 ! monoatomic cation transmembrane transporter activity -is_a: GO:0022890 ! inorganic cation transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:25213 ! metal cation -relationship: has_primary_input CHEBI:25213 ! metal cation -relationship: part_of GO:0030001 ! metal ion transport - [Term] id: GO:0046877 name: regulation of saliva secretion @@ -98230,20 +84558,6 @@ def: "The controlled release of a substance by a cell or a tissue." [GOC:ai] subset: goslim_pir is_a: GO:0006810 ! transport -[Term] -id: GO:0046906 -name: tetrapyrrole binding -namespace: molecular_function -def: "Binding to a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position." [GOC:curators, ISBN:0198506732] -subset: goslim_metagenomics -subset: goslim_pir -synonym: "porphyrin binding" NARROW [] -is_a: GO:0097159 ! organic cyclic compound binding -is_a: GO:1901363 ! heterocyclic compound binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:26932 ! tetrapyrrole -relationship: has_input CHEBI:26932 ! tetrapyrrole - [Term] id: GO:0046907 name: intracellular transport @@ -98261,27 +84575,6 @@ relationship: occurs_in GO:0005622 ! intracellular anatomical structure created_by: jl creation_date: 2013-12-18T14:04:50Z -[Term] -id: GO:0046914 -name: transition metal ion binding -namespace: molecular_function -def: "Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver." [ISBN:0198506732] -is_a: GO:0046872 ! metal ion binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:33515 ! transition element cation -relationship: has_input CHEBI:33515 ! transition element cation - -[Term] -id: GO:0046915 -name: transition metal ion transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver." [ISBN:0198506732] -is_a: GO:0046873 ! metal ion transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:33515 ! transition element cation -relationship: has_primary_input CHEBI:33515 ! transition element cation -relationship: part_of GO:0000041 ! transition metal ion transport - [Term] id: GO:0046928 name: regulation of neurotransmitter secretion @@ -98316,10 +84609,10 @@ id: GO:0046942 name: carboxylic acid transport namespace: biological_process def: "The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:ai] -is_a: GO:0015711 ! organic anion transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:29067 ! carboxylic acid anion -relationship: has_primary_input CHEBI:29067 ! carboxylic acid anion +intersection_of: has_primary_input CHEBI:29067 +relationship: has_primary_input CHEBI:29067 [Term] id: GO:0046943 @@ -98327,10 +84620,10 @@ name: carboxylic acid transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:ai] xref: Reactome:R-HSA-390347 "Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane" -is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:29067 ! carboxylic acid anion -relationship: has_primary_input CHEBI:29067 ! carboxylic acid anion +intersection_of: has_primary_input CHEBI:29067 +relationship: has_primary_input CHEBI:29067 relationship: part_of GO:1905039 ! carboxylic acid transmembrane transport [Term] @@ -98364,17 +84657,6 @@ synonym: "beta chemokine receptor ligand" NARROW [] synonym: "CCR chemokine receptor ligand" NARROW [] is_a: GO:0042379 ! chemokine receptor binding -[Term] -id: GO:0048029 -name: monosaccharide binding -namespace: molecular_function -def: "Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." [GOC:jid] -is_a: GO:0030246 ! carbohydrate binding -is_a: GO:0036094 ! small molecule binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:35381 ! monosaccharide -relationship: has_input CHEBI:35381 ! monosaccharide - [Term] id: GO:0048048 name: embryonic eye morphogenesis @@ -98663,10 +84945,10 @@ name: epinephrine transport namespace: biological_process def: "The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jid] synonym: "adrenaline transport" EXACT [] -is_a: GO:0051937 ! catecholamine transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:33568 ! adrenaline -relationship: has_primary_input CHEBI:33568 ! adrenaline +intersection_of: has_primary_input CHEBI:33568 +relationship: has_primary_input CHEBI:33568 [Term] id: GO:0048242 @@ -98674,10 +84956,10 @@ name: epinephrine secretion namespace: biological_process def: "The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system." [GOC:ef, GOC:jid] synonym: "adrenaline secretion" EXACT [] +is_a: GO:0046903 ! secretion is_a: GO:0048241 ! epinephrine transport -is_a: GO:0050432 ! catecholamine secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:33568 ! adrenaline +intersection_of: has_primary_input CHEBI:33568 [Term] id: GO:0048243 @@ -98689,7 +84971,7 @@ is_a: GO:0015874 ! norepinephrine transport is_a: GO:0023061 ! signal release is_a: GO:0050432 ! catecholamine secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) +intersection_of: has_primary_input CHEBI:72587 [Term] id: GO:0048245 @@ -99052,7 +85334,7 @@ relationship: results_in_formation_of UBERON:0003064 ! intermediate mesoderm id: GO:0048468 name: cell development namespace: biological_process -def: "The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:go_curators] +def: "The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place." [GOC:go_curators] subset: goslim_candida synonym: "terminal differentiation" RELATED [GOC:dph, GOC:tb] is_a: GO:0048856 ! anatomical structure development @@ -99061,12 +85343,13 @@ intersection_of: GO:0008150 ! biological_process intersection_of: results_in_development_of CL:0000000 ! cell relationship: part_of GO:0030154 ! cell differentiation relationship: results_in_development_of CL:0000000 ! cell +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI [Term] id: GO:0048469 name: cell maturation namespace: biological_process -def: "A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state." [GOC:go_curators] +def: "The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state." [GOC:go_curators] subset: goslim_pir synonym: "functional differentiation" RELATED [GOC:dph] is_a: GO:0021700 ! developmental maturation @@ -99075,6 +85358,7 @@ intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000000 ! cell relationship: part_of GO:0048468 ! cell development relationship: results_in_maturation_of CL:0000000 ! cell +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI [Term] id: GO:0048477 @@ -99406,11 +85690,9 @@ namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus." [GOC:go_curators] synonym: "response to steroid hormone stimulus" EXACT [GOC:dos] is_a: GO:0009725 ! response to hormone -is_a: GO:0014070 ! response to organic cyclic compound -is_a: GO:0033993 ! response to lipid intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:26764 ! steroid hormone -relationship: has_input CHEBI:26764 ! steroid hormone +intersection_of: has_input CHEBI:26764 +relationship: has_input CHEBI:26764 [Term] id: GO:0048546 @@ -101026,8 +87308,8 @@ def: "Any biological process involved in the maintenance of an internal steady s subset: goslim_drosophila is_a: GO:0042592 ! homeostatic process intersection_of: GO:0042592 ! homeostatic process -intersection_of: regulates_levels_of CHEBI:24431 ! chemical entity -relationship: regulates_levels_of CHEBI:24431 ! chemical entity +intersection_of: regulates_levels_of CHEBI:24431 +relationship: regulates_levels_of CHEBI:24431 [Term] id: GO:0048880 @@ -101521,7 +87803,7 @@ def: "The regulated release of catecholamines by a cell. The catecholamines are is_a: GO:0032940 ! secretion by cell is_a: GO:0051937 ! catecholamine transport intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:33567 ! catecholamine +intersection_of: has_primary_input CHEBI:33567 [Term] id: GO:0050433 @@ -101563,21 +87845,21 @@ id: GO:0050657 name: nucleic acid transport namespace: biological_process def: "The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, ISBN:0198506732] -is_a: GO:0015931 ! nucleobase-containing compound transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:33696 ! nucleic acid -relationship: has_primary_input CHEBI:33696 ! nucleic acid +intersection_of: has_primary_input CHEBI:33696 +relationship: has_primary_input CHEBI:33696 [Term] id: GO:0050658 name: RNA transport namespace: biological_process def: "The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] -is_a: GO:0050657 ! nucleic acid transport +is_a: GO:0006810 ! transport is_a: GO:0051236 ! establishment of RNA localization intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:33697 ! ribonucleic acid -relationship: has_primary_input CHEBI:33697 ! ribonucleic acid +intersection_of: has_primary_input CHEBI:33697 +relationship: has_primary_input CHEBI:33697 [Term] id: GO:0050670 @@ -101863,7 +88145,6 @@ namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids." [GOC:ai] synonym: "regulation of lipoprotein metabolism" EXACT [] is_a: GO:0031323 ! regulation of cellular metabolic process -is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042157 ! lipoprotein metabolic process relationship: regulates GO:0042157 ! lipoprotein metabolic process @@ -101881,7 +88162,6 @@ synonym: "up-regulation of lipoprotein metabolic process" EXACT [] synonym: "upregulation of lipoprotein metabolic process" EXACT [] is_a: GO:0031328 ! positive regulation of cellular biosynthetic process is_a: GO:0050746 ! regulation of lipoprotein metabolic process -is_a: GO:0051247 ! positive regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042157 ! lipoprotein metabolic process relationship: positively_regulates GO:0042157 ! lipoprotein metabolic process @@ -101898,7 +88178,6 @@ synonym: "inhibition of lipoprotein metabolic process" NARROW [] synonym: "negative regulation of lipoprotein metabolism" EXACT [] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0050746 ! regulation of lipoprotein metabolic process -is_a: GO:0051248 ! negative regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042157 ! lipoprotein metabolic process relationship: negatively_regulates GO:0042157 ! lipoprotein metabolic process @@ -101908,7 +88187,7 @@ id: GO:0050764 name: regulation of phagocytosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material." [GOC:ai] -is_a: GO:0060627 ! regulation of vesicle-mediated transport +is_a: GO:0030100 ! regulation of endocytosis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006909 ! phagocytosis relationship: never_in_taxon NCBITaxon:147537 ! Saccharomycotina @@ -101923,8 +88202,8 @@ synonym: "down regulation of phagocytosis" EXACT [] synonym: "down-regulation of phagocytosis" EXACT [] synonym: "downregulation of phagocytosis" EXACT [] synonym: "inhibition of phagocytosis" NARROW [] +is_a: GO:0045806 ! negative regulation of endocytosis is_a: GO:0050764 ! regulation of phagocytosis -is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006909 ! phagocytosis relationship: negatively_regulates GO:0006909 ! phagocytosis @@ -101939,8 +88218,8 @@ synonym: "stimulation of phagocytosis" NARROW [] synonym: "up regulation of phagocytosis" EXACT [] synonym: "up-regulation of phagocytosis" EXACT [] synonym: "upregulation of phagocytosis" EXACT [] +is_a: GO:0045807 ! positive regulation of endocytosis is_a: GO:0050764 ! regulation of phagocytosis -is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006909 ! phagocytosis relationship: positively_regulates GO:0006909 ! phagocytosis @@ -102207,8 +88486,8 @@ synonym: "negative regulation of crystal formation" RELATED [] synonym: "regulation of ion homeostasis" RELATED [] is_a: GO:0048878 ! chemical homeostasis intersection_of: GO:0048878 ! chemical homeostasis -intersection_of: regulates_levels_of CHEBI:24867 ! monoatomic ion -relationship: regulates_levels_of CHEBI:24867 ! monoatomic ion +intersection_of: regulates_levels_of CHEBI:24867 +relationship: regulates_levels_of CHEBI:24867 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24455" xsd:anyURI [Term] @@ -102717,11 +88996,11 @@ namespace: biological_process def: "A chemical homeostatic process involved in the maintenance of a steady state level of water within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell." [GOC:dph, GOC:tb] synonym: "body fluid osmoregulation" RELATED [GOC:dph, GOC:tb] synonym: "multicellular organismal water homeostasis" EXACT [] -is_a: GO:0030104 ! water homeostasis +is_a: GO:0048871 ! multicellular organismal-level homeostasis is_a: GO:0050878 ! regulation of body fluid levels -is_a: GO:0140962 ! multicellular organismal-level chemical homeostasis intersection_of: GO:0048871 ! multicellular organismal-level homeostasis -intersection_of: regulates_levels_of CHEBI:15377 ! water +intersection_of: regulates_levels_of CHEBI:15377 +relationship: regulates_levels_of CHEBI:15377 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24554" xsd:anyURI [Term] @@ -103471,21 +89750,20 @@ id: GO:0051027 name: DNA transport namespace: biological_process def: "The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] -is_a: GO:0050657 ! nucleic acid transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:16991 ! deoxyribonucleic acid -relationship: has_primary_input CHEBI:16991 ! deoxyribonucleic acid +intersection_of: has_primary_input CHEBI:16991 +relationship: has_primary_input CHEBI:16991 [Term] id: GO:0051032 name: nucleic acid transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information." [GOC:ai] -is_a: GO:0015932 ! nucleobase-containing compound transmembrane transporter activity -is_a: GO:0022884 ! macromolecule transmembrane transporter activity +is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:33696 ! nucleic acid -relationship: has_primary_input CHEBI:33696 ! nucleic acid +intersection_of: has_primary_input CHEBI:33696 +relationship: has_primary_input CHEBI:33696 relationship: part_of GO:0050657 ! nucleic acid transport [Term] @@ -103494,10 +89772,10 @@ name: RNA transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other." [GOC:ai] xref: Reactome:R-HSA-203906 "Exportin complex translocates pre-miRNA to cytosol" -is_a: GO:0051032 ! nucleic acid transmembrane transporter activity +is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:33697 ! ribonucleic acid -relationship: has_primary_input CHEBI:33697 ! ribonucleic acid +intersection_of: has_primary_input CHEBI:33697 +relationship: has_primary_input CHEBI:33697 relationship: part_of GO:0050658 ! RNA transport [Term] @@ -103505,10 +89783,10 @@ id: GO:0051035 name: DNA transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other." [GOC:ai] -is_a: GO:0051032 ! nucleic acid transmembrane transporter activity +is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:16991 ! deoxyribonucleic acid -relationship: has_primary_input CHEBI:16991 ! deoxyribonucleic acid +intersection_of: has_primary_input CHEBI:16991 +relationship: has_primary_input CHEBI:16991 relationship: part_of GO:0051027 ! DNA transport [Term] @@ -103601,7 +89879,6 @@ namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai] subset: goslim_yeast synonym: "regulation of DNA metabolism" EXACT [] -is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006259 ! DNA metabolic process @@ -103618,7 +89895,6 @@ synonym: "downregulation of DNA metabolic process" EXACT [] synonym: "inhibition of DNA metabolic process" NARROW [] synonym: "negative regulation of DNA metabolism" EXACT [] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process -is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006259 ! DNA metabolic process @@ -103636,7 +89912,6 @@ synonym: "up regulation of DNA metabolic process" EXACT [] synonym: "up-regulation of DNA metabolic process" EXACT [] synonym: "upregulation of DNA metabolic process" EXACT [] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process -is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006259 ! DNA metabolic process @@ -103798,17 +90073,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003677 ! DNA binding relationship: regulates GO:0003677 ! DNA binding -[Term] -id: GO:0051119 -name: sugar transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] -synonym: "sugar/polyol channel activity" NARROW [] -xref: Reactome:R-HSA-428779 "GLUT7 and GLUT11 transport glucose and fructose" -xref: Reactome:R-HSA-8875902 "SLC45A3 transports Glc from extracellular region to cytosol" -xref: Reactome:R-HSA-8876319 "SLC50A1 transports Glc from cytosol to extracellular region" -is_a: GO:0015144 ! carbohydrate transmembrane transporter activity - [Term] id: GO:0051128 name: regulation of cellular component organization @@ -104277,54 +90541,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006807 ! nitrogen compound metabolic process relationship: positively_regulates GO:0006807 ! nitrogen compound metabolic process -[Term] -id: GO:0051174 -name: regulation of phosphorus metabolic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:ai] -synonym: "regulation of phosphorus metabolism" EXACT [] -is_a: GO:0031323 ! regulation of cellular metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0006793 ! phosphorus metabolic process -relationship: regulates GO:0006793 ! phosphorus metabolic process - -[Term] -id: GO:0051175 -name: negative regulation of sulfur metabolic process -namespace: biological_process -def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." [GOC:ai] -synonym: "down regulation of sulfur metabolic process" EXACT [] -synonym: "down-regulation of sulfur metabolic process" EXACT [] -synonym: "downregulation of sulfur metabolic process" EXACT [] -synonym: "inhibition of sulfur metabolic process" NARROW [] -synonym: "negative regulation of sulfur metabolism" EXACT [] -synonym: "negative regulation of sulphur metabolic process" EXACT [] -synonym: "negative regulation of sulphur metabolism" EXACT [] -is_a: GO:0031324 ! negative regulation of cellular metabolic process -is_a: GO:0042762 ! regulation of sulfur metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0006790 ! sulfur compound metabolic process -relationship: negatively_regulates GO:0006790 ! sulfur compound metabolic process - -[Term] -id: GO:0051176 -name: positive regulation of sulfur metabolic process -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." [GOC:ai] -synonym: "activation of sulfur metabolic process" NARROW [] -synonym: "positive regulation of sulfur metabolism" EXACT [] -synonym: "positive regulation of sulphur metabolic process" EXACT [] -synonym: "positive regulation of sulphur metabolism" EXACT [] -synonym: "stimulation of sulfur metabolic process" NARROW [] -synonym: "up regulation of sulfur metabolic process" EXACT [] -synonym: "up-regulation of sulfur metabolic process" EXACT [] -synonym: "upregulation of sulfur metabolic process" EXACT [] -is_a: GO:0031325 ! positive regulation of cellular metabolic process -is_a: GO:0042762 ! regulation of sulfur metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0006790 ! sulfur compound metabolic process -relationship: positively_regulates GO:0006790 ! sulfur compound metabolic process - [Term] id: GO:0051179 name: localization @@ -104480,8 +90696,6 @@ def: "Any process that modulates the frequency, rate or extent of the chemical r synonym: "regulation of cellular protein metabolic process" RELATED [] synonym: "regulation of cellular protein metabolism" RELATED [] synonym: "regulation of protein metabolism" EXACT [] -is_a: GO:0051171 ! regulation of nitrogen compound metabolic process -is_a: GO:0060255 ! regulation of macromolecule metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0019538 ! protein metabolic process @@ -104507,8 +90721,7 @@ synonym: "up-regulation of cellular protein metabolic process" EXACT [] synonym: "up-regulation of protein metabolic process" EXACT [] synonym: "upregulation of cellular protein metabolic process" EXACT [] synonym: "upregulation of protein metabolic process" EXACT [] -is_a: GO:0010604 ! positive regulation of macromolecule metabolic process -is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0019538 ! protein metabolic process @@ -104532,8 +90745,7 @@ synonym: "inhibition of protein metabolic process" NARROW [] synonym: "negative regulation of cellular protein metabolic process" EXACT [] synonym: "negative regulation of cellular protein metabolism" EXACT [] synonym: "negative regulation of protein metabolism" EXACT [] -is_a: GO:0010605 ! negative regulation of macromolecule metabolic process -is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0019538 ! protein metabolic process @@ -104587,8 +90799,7 @@ name: regulation of RNA metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] synonym: "regulation of RNA metabolism" EXACT [] -is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process -is_a: GO:0060255 ! regulation of macromolecule metabolic process +is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016070 ! RNA metabolic process relationship: regulates GO:0016070 ! RNA metabolic process @@ -104603,8 +90814,7 @@ synonym: "down-regulation of RNA metabolic process" EXACT [] synonym: "downregulation of RNA metabolic process" EXACT [] synonym: "inhibition of RNA metabolic process" NARROW [] synonym: "negative regulation of RNA metabolism" EXACT [] -is_a: GO:0010605 ! negative regulation of macromolecule metabolic process -is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process +is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0051252 ! regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016070 ! RNA metabolic process @@ -104621,8 +90831,7 @@ synonym: "stimulation of RNA metabolic process" NARROW [] synonym: "up regulation of RNA metabolic process" EXACT [] synonym: "up-regulation of RNA metabolic process" EXACT [] synonym: "upregulation of RNA metabolic process" EXACT [] -is_a: GO:0010604 ! positive regulation of macromolecule metabolic process -is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process +is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0051252 ! regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016070 ! RNA metabolic process @@ -104728,6 +90937,8 @@ intersection_of: has_part GO:0140013 ! meiotic nuclear division relationship: has_part GO:0140013 ! meiotic nuclear division relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota +relationship: part_of GO:0019953 ! sexual reproduction +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24599" xsd:anyURI [Term] id: GO:0051336 @@ -104899,11 +91110,10 @@ name: serotonin binding namespace: molecular_function def: "Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:ai] synonym: "5-hydroxytryptamine binding" EXACT [] -is_a: GO:0043169 ! cation binding is_a: GO:0043176 ! amine binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:350546 ! serotonin(1+) -relationship: has_input CHEBI:350546 ! serotonin(1+) +intersection_of: has_input CHEBI:350546 +relationship: has_input CHEBI:350546 [Term] id: GO:0051379 @@ -104911,10 +91121,10 @@ name: epinephrine binding namespace: molecular_function def: "Binding to epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine." [GOC:ai] synonym: "adrenaline binding" EXACT [] -is_a: GO:1901338 ! catecholamine binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:33568 ! adrenaline -relationship: has_input CHEBI:33568 ! adrenaline +intersection_of: has_input CHEBI:33568 +relationship: has_input CHEBI:33568 [Term] id: GO:0051380 @@ -104922,20 +91132,20 @@ name: norepinephrine binding namespace: molecular_function def: "Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." [GOC:ai] synonym: "noradrenaline binding" EXACT [] -is_a: GO:0043169 ! cation binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:72587 ! (R)-noradrenaline(1+) -relationship: has_input CHEBI:72587 ! (R)-noradrenaline(1+) +intersection_of: has_input CHEBI:72587 +relationship: has_input CHEBI:72587 [Term] id: GO:0051381 name: histamine binding namespace: molecular_function def: "Binding to histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans." [GOC:ai] -is_a: GO:0043169 ! cation binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:58432 ! histaminium -relationship: has_input CHEBI:58432 ! histaminium +intersection_of: has_input CHEBI:58432 +relationship: has_input CHEBI:58432 [Term] id: GO:0051384 @@ -104943,10 +91153,10 @@ name: response to glucocorticoid namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects." [GOC:ai, PMID:9884123] synonym: "response to glucocorticoid stimulus" EXACT [GOC:dos] -is_a: GO:0031960 ! response to corticosteroid +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:24261 ! glucocorticoid -relationship: has_input CHEBI:24261 ! glucocorticoid +intersection_of: has_input CHEBI:24261 +relationship: has_input CHEBI:24261 [Term] id: GO:0051385 @@ -104954,10 +91164,10 @@ name: response to mineralocorticoid namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance." [GOC:ai, PMID:9884123] synonym: "response to mineralocorticoid stimulus" EXACT [GOC:dos] -is_a: GO:0031960 ! response to corticosteroid +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:25354 ! mineralocorticoid -relationship: has_input CHEBI:25354 ! mineralocorticoid +intersection_of: has_input CHEBI:25354 +relationship: has_input CHEBI:25354 [Term] id: GO:0051402 @@ -104988,8 +91198,8 @@ synonym: "detoxification of nitrogenous compound" EXACT [] synonym: "nitric oxide (NO) detoxification" NARROW [] is_a: GO:0098754 ! detoxification intersection_of: GO:0098754 ! detoxification -intersection_of: has_input CHEBI:51143 ! nitrogen molecular entity -relationship: has_input CHEBI:51143 ! nitrogen molecular entity +intersection_of: has_input CHEBI:51143 +relationship: has_input CHEBI:51143 relationship: part_of GO:1901698 ! response to nitrogen compound [Term] @@ -105080,8 +91290,8 @@ synonym: "corticotropic hormone secretion" EXACT [] is_a: GO:0030072 ! peptide hormone secretion is_a: GO:0060986 ! endocrine hormone secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:3892 ! corticotropin -relationship: has_primary_input CHEBI:3892 ! corticotropin +intersection_of: has_primary_input CHEBI:3892 +relationship: has_primary_input CHEBI:3892 [Term] id: GO:0051459 @@ -105306,10 +91516,10 @@ name: response to calcium ion namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus." [GOC:ai] synonym: "response to Ca2+ ion" EXACT [] -is_a: GO:0010038 ! response to metal ion +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:29108 ! calcium(2+) -relationship: has_input CHEBI:29108 ! calcium(2+) +intersection_of: has_input CHEBI:29108 +relationship: has_input CHEBI:29108 [Term] id: GO:0051602 @@ -105369,10 +91579,10 @@ id: GO:0051608 name: histamine transport namespace: biological_process def: "The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans." [GOC:ai] -is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:58432 ! histaminium -relationship: has_primary_input CHEBI:58432 ! histaminium +intersection_of: has_primary_input CHEBI:58432 +relationship: has_primary_input CHEBI:58432 [Term] id: GO:0051620 @@ -105388,7 +91598,7 @@ synonym: "norepinephrine reuptake" EXACT [] is_a: GO:0015874 ! norepinephrine transport is_a: GO:0090493 ! catecholamine uptake intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) +intersection_of: has_primary_input CHEBI:72587 intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure intersection_of: has_target_start_location GO:0005576 ! extracellular region @@ -105451,11 +91661,12 @@ synonym: "adrenaline uptake" EXACT [] synonym: "epinephrine import" EXACT [GOC:dph, GOC:tb] synonym: "epinephrine reuptake" EXACT [] is_a: GO:0048241 ! epinephrine transport -is_a: GO:0090493 ! catecholamine uptake intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:33568 ! adrenaline +intersection_of: has_primary_input CHEBI:33568 intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure intersection_of: has_target_start_location GO:0005576 ! extracellular region +relationship: has_target_end_location GO:0005622 ! intracellular anatomical structure +relationship: has_target_start_location GO:0005576 ! extracellular region [Term] id: GO:0051626 @@ -105510,11 +91721,12 @@ namespace: biological_process def: "The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:ai] synonym: "acetylcholine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0015870 ! acetylcholine transport -is_a: GO:0098657 ! import into cell intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:15355 ! acetylcholine +intersection_of: has_primary_input CHEBI:15355 intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure intersection_of: has_target_start_location GO:0005576 ! extracellular region +relationship: has_target_end_location GO:0005622 ! intracellular anatomical structure +relationship: has_target_start_location GO:0005576 ! extracellular region [Term] id: GO:0051631 @@ -105771,39 +91983,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007049 ! cell cycle relationship: regulates GO:0007049 ! cell cycle -[Term] -id: GO:0051761 -name: sesquiterpene metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene." [GOC:ai] -synonym: "sesquiterpene metabolism" EXACT [] -is_a: GO:0042214 ! terpene metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:35189 ! sesquiterpene -relationship: has_primary_input_or_output CHEBI:35189 ! sesquiterpene - -[Term] -id: GO:0051762 -name: sesquiterpene biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene." [GOC:ai] -is_a: GO:0046246 ! terpene biosynthetic process -is_a: GO:0051761 ! sesquiterpene metabolic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:35189 ! sesquiterpene -relationship: has_primary_output CHEBI:35189 ! sesquiterpene - -[Term] -id: GO:0051763 -name: sesquiterpene catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene." [GOC:ai] -is_a: GO:0046247 ! terpene catabolic process -is_a: GO:0051761 ! sesquiterpene metabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:35189 ! sesquiterpene -relationship: has_primary_input CHEBI:35189 ! sesquiterpene - [Term] id: GO:0051767 name: nitric-oxide synthase biosynthetic process @@ -105991,23 +92170,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0000280 ! nuclear division relationship: positively_regulates GO:0000280 ! nuclear division -[Term] -id: GO:0051790 -name: short-chain fatty acid biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of fatty acids with a chain length of less than C6." [Wikipedia:Fatty_acid_metabolism] -synonym: "short chain fatty acid biosynthesis" EXACT [] -synonym: "short chain fatty acid biosynthetic process" EXACT [] -synonym: "short-chain fatty acid anabolism" EXACT [] -synonym: "short-chain fatty acid biosynthesis" EXACT [] -synonym: "short-chain fatty acid formation" EXACT [] -synonym: "short-chain fatty acid synthesis" EXACT [] -is_a: GO:0006633 ! fatty acid biosynthetic process -is_a: GO:0046459 ! short-chain fatty acid metabolic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:58951 ! short-chain fatty acid anion -relationship: has_primary_output CHEBI:58951 ! short-chain fatty acid anion - [Term] id: GO:0051797 name: regulation of hair follicle development @@ -106052,17 +92214,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001942 ! hair follicle development relationship: negatively_regulates GO:0001942 ! hair follicle development -[Term] -id: GO:0051861 -name: glycolipid binding -namespace: molecular_function -def: "Binding to a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate." [PMID:19635802] -is_a: GO:0008289 ! lipid binding -is_a: GO:0097367 ! carbohydrate derivative binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:33563 ! glycolipid -relationship: has_input CHEBI:33563 ! glycolipid - [Term] id: GO:0051875 name: pigment granule localization @@ -106153,7 +92304,7 @@ name: regulation of calcium ion transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "regulation of calcium transport" EXACT [] -is_a: GO:0010959 ! regulation of metal ion transport +is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006816 ! calcium ion transport relationship: regulates GO:0006816 ! calcium ion transport @@ -106168,7 +92319,7 @@ synonym: "down-regulation of calcium ion transport" EXACT [] synonym: "downregulation of calcium ion transport" EXACT [] synonym: "inhibition of calcium ion transport" NARROW [] synonym: "negative regulation of calcium transport" EXACT [] -is_a: GO:0043271 ! negative regulation of monoatomic ion transport +is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051924 ! regulation of calcium ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006816 ! calcium ion transport @@ -106185,7 +92336,7 @@ synonym: "stimulation of calcium ion transport" NARROW [] synonym: "up regulation of calcium ion transport" EXACT [] synonym: "up-regulation of calcium ion transport" EXACT [] synonym: "upregulation of calcium ion transport" EXACT [] -is_a: GO:0043270 ! positive regulation of monoatomic ion transport +is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051924 ! regulation of calcium ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006816 ! calcium ion transport @@ -106221,7 +92372,7 @@ synonym: "synaptic transmission, GABA mediated" EXACT [] synonym: "synaptic transmission, gamma-aminobutyric acid mediated" EXACT [] synonym: "synaptic transmission, gamma-aminobutyric acid-ergic" EXACT [] is_a: GO:0007268 ! chemical synaptic transmission -relationship: has_participant CHEBI:59888 ! gamma-aminobutyric acid zwitterion +relationship: has_participant CHEBI:59888 relationship: has_participant CL:0000617 ! GABAergic neuron [Term] @@ -106229,11 +92380,21 @@ id: GO:0051937 name: catecholamine transport namespace: biological_process def: "The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:ai, ISBN:0198506732] -is_a: GO:0015844 ! monoamine transport -is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:33567 ! catecholamine -relationship: has_primary_input CHEBI:33567 ! catecholamine +intersection_of: has_primary_input CHEBI:33567 +relationship: has_primary_input CHEBI:33567 + +[Term] +id: GO:0051938 +name: L-glutamate import +namespace: biological_process +def: "The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle." [GOC:ai, GOC:jsg, GOC:mah] +synonym: "L-glutamate uptake" EXACT [GOC:dph, GOC:tb] +is_a: GO:0015800 ! acidic amino acid transport +intersection_of: GO:0006810 ! transport +intersection_of: has_primary_input CHEBI:29985 +relationship: has_primary_input CHEBI:29985 [Term] id: GO:0051939 @@ -106247,7 +92408,7 @@ synonym: "gamma-aminobutyric acid uptake" EXACT [GOC:dph, GOC:tb] is_a: GO:0015800 ! acidic amino acid transport is_a: GO:0015812 ! gamma-aminobutyric acid transport intersection_of: GO:0015800 ! acidic amino acid transport -intersection_of: has_primary_input CHEBI:59888 ! gamma-aminobutyric acid zwitterion +intersection_of: has_primary_input CHEBI:59888 [Term] id: GO:0051952 @@ -106295,7 +92456,6 @@ id: GO:0051955 name: regulation of amino acid transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] -is_a: GO:0032890 ! regulation of organic acid transport is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006865 ! amino acid transport @@ -106311,7 +92471,6 @@ synonym: "down-regulation of amino acid transport" EXACT [] synonym: "downregulation of amino acid transport" EXACT [] synonym: "inhibition of amino acid transport" NARROW [] synonym: "negative regulation of amino acid transmembrane transport" EXACT [GOC:mah] -is_a: GO:0032891 ! negative regulation of organic acid transport is_a: GO:0051953 ! negative regulation of amine transport is_a: GO:0051955 ! regulation of amino acid transport intersection_of: GO:0065007 ! biological regulation @@ -106329,7 +92488,6 @@ synonym: "stimulation of amino acid transport" NARROW [] synonym: "up regulation of amino acid transport" EXACT [] synonym: "up-regulation of amino acid transport" EXACT [] synonym: "upregulation of amino acid transport" EXACT [] -is_a: GO:0032892 ! positive regulation of organic acid transport is_a: GO:0051954 ! positive regulation of amine transport is_a: GO:0051955 ! regulation of amino acid transport intersection_of: GO:0065007 ! biological regulation @@ -106584,8 +92742,8 @@ is_a: GO:0046483 ! heterocycle metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:24780 ! imidazoles -relationship: has_primary_input_or_output CHEBI:24780 ! imidazoles +intersection_of: has_primary_input_or_output CHEBI:24780 +relationship: has_primary_input_or_output CHEBI:24780 [Term] id: GO:0052805 @@ -106595,15 +92753,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of imidazol synonym: "imidazole breakdown" EXACT [] synonym: "imidazole catabolism" EXACT [] synonym: "imidazole degradation" EXACT [] -is_a: GO:0019439 ! aromatic compound catabolic process is_a: GO:0044270 ! cellular nitrogen compound catabolic process -is_a: GO:0046700 ! heterocycle catabolic process is_a: GO:0052803 ! imidazole-containing compound metabolic process -is_a: GO:1901361 ! organic cyclic compound catabolic process -is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:24780 ! imidazoles -relationship: has_primary_input CHEBI:24780 ! imidazoles +intersection_of: has_primary_input CHEBI:24780 +relationship: has_primary_input CHEBI:24780 [Term] id: GO:0055001 @@ -106932,63 +93086,16 @@ is_a: GO:0055057 ! neuroblast division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: has_input CL:0000031 ! neuroblast (sensu Vertebrata) -[Term] -id: GO:0055062 -name: phosphate ion homeostasis -namespace: biological_process -def: "Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell." [GOC:jid, GOC:mah] -is_a: GO:0098771 ! inorganic ion homeostasis -intersection_of: GO:0048878 ! chemical homeostasis -intersection_of: regulates_levels_of CHEBI:35780 ! phosphate ion -relationship: regulates_levels_of CHEBI:35780 ! phosphate ion - -[Term] -id: GO:0055063 -name: sulfate ion homeostasis -namespace: biological_process -alt_id: GO:0080174 -def: "Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell." [GOC:jid, GOC:mah] -synonym: "sulfate homeostasis" EXACT [] -synonym: "sulphate ion homeostasis" EXACT [] -is_a: GO:0098771 ! inorganic ion homeostasis -intersection_of: GO:0048878 ! chemical homeostasis -intersection_of: regulates_levels_of CHEBI:16189 ! sulfate -relationship: regulates_levels_of CHEBI:16189 ! sulfate - -[Term] -id: GO:0055072 -name: iron ion homeostasis -namespace: biological_process -def: "Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah] -synonym: "iron homeostasis" BROAD [] -is_a: GO:0055080 ! monoatomic cation homeostasis -is_a: GO:0098771 ! inorganic ion homeostasis -intersection_of: GO:0048878 ! chemical homeostasis -intersection_of: regulates_levels_of CHEBI:24875 ! iron cation -relationship: regulates_levels_of CHEBI:24875 ! iron cation - [Term] id: GO:0055074 name: calcium ion homeostasis namespace: biological_process def: "Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell." [GOC:ceb, GOC:jid, GOC:mah] synonym: "regulation of calcium ion concentration" EXACT [] -is_a: GO:0055080 ! monoatomic cation homeostasis -is_a: GO:0098771 ! inorganic ion homeostasis -intersection_of: GO:0048878 ! chemical homeostasis -intersection_of: regulates_levels_of CHEBI:29108 ! calcium(2+) -relationship: regulates_levels_of CHEBI:29108 ! calcium(2+) - -[Term] -id: GO:0055078 -name: sodium ion homeostasis -namespace: biological_process -def: "Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah] -is_a: GO:0055080 ! monoatomic cation homeostasis -is_a: GO:0098771 ! inorganic ion homeostasis +is_a: GO:0048878 ! chemical homeostasis intersection_of: GO:0048878 ! chemical homeostasis -intersection_of: regulates_levels_of CHEBI:29101 ! sodium(1+) -relationship: regulates_levels_of CHEBI:29101 ! sodium(1+) +intersection_of: regulates_levels_of CHEBI:29108 +relationship: regulates_levels_of CHEBI:29108 [Term] id: GO:0055080 @@ -106996,10 +93103,10 @@ name: monoatomic cation homeostasis namespace: biological_process def: "Any process involved in the maintenance of an internal steady state of monoatomic cations within an organism or cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom." [GOC:ceb, GOC:jid, GOC:mah] synonym: "cation homeostasis" BROAD [] -is_a: GO:0050801 ! monoatomic ion homeostasis +is_a: GO:0048878 ! chemical homeostasis intersection_of: GO:0048878 ! chemical homeostasis -intersection_of: regulates_levels_of CHEBI:23906 ! monoatomic cation -relationship: regulates_levels_of CHEBI:23906 ! monoatomic cation +intersection_of: regulates_levels_of CHEBI:23906 +relationship: regulates_levels_of CHEBI:23906 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24455" xsd:anyURI [Term] @@ -107011,7 +93118,7 @@ synonym: "cellular chemical homeostasis" EXACT [] is_a: GO:0019725 ! cellular homeostasis is_a: GO:0048878 ! chemical homeostasis intersection_of: GO:0019725 ! cellular homeostasis -intersection_of: regulates_levels_of CHEBI:24431 ! chemical entity +intersection_of: regulates_levels_of CHEBI:24431 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24514" xsd:anyURI [Term] @@ -107036,21 +93143,6 @@ relationship: results_in_transport_across GO:0016020 ! membrane created_by: tb creation_date: 2015-10-21T13:22:47Z -[Term] -id: GO:0055086 -name: nucleobase-containing small molecule metabolic process -namespace: biological_process -def: "The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide." [GOC:vw] -subset: goslim_drosophila -subset: goslim_generic -subset: goslim_pombe -subset: goslim_yeast -subset: prokaryote_subset -synonym: "nucleobase, nucleoside and nucleotide metabolic process" RELATED [] -synonym: "nucleobase, nucleoside and nucleotide metabolism" EXACT [] -is_a: GO:0006139 ! nucleobase-containing compound metabolic process -is_a: GO:0044281 ! small molecule metabolic process - [Term] id: GO:0055088 name: lipid homeostasis @@ -107058,18 +93150,8 @@ namespace: biological_process def: "Any process involved in the maintenance of an internal steady state of lipid within an organism or cell." [GOC:BHF, GOC:rl] is_a: GO:0048878 ! chemical homeostasis intersection_of: GO:0048878 ! chemical homeostasis -intersection_of: regulates_levels_of CHEBI:18059 ! lipid -relationship: regulates_levels_of CHEBI:18059 ! lipid - -[Term] -id: GO:0055089 -name: fatty acid homeostasis -namespace: biological_process -def: "Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell." [GOC:BHF, GOC:rl] -is_a: GO:0055088 ! lipid homeostasis -intersection_of: GO:0048878 ! chemical homeostasis -intersection_of: regulates_levels_of CHEBI:28868 ! fatty acid anion -relationship: regulates_levels_of CHEBI:28868 ! fatty acid anion +intersection_of: regulates_levels_of CHEBI:18059 +relationship: regulates_levels_of CHEBI:18059 [Term] id: GO:0055094 @@ -107078,10 +93160,9 @@ namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus." [GOC:BHF, GOC:rl] synonym: "response to lipoprotein particle stimulus" EXACT [GOC:dos] is_a: GO:0009719 ! response to endogenous stimulus -is_a: GO:0010243 ! response to organonitrogen compound intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:6495 ! lipoprotein -relationship: has_input CHEBI:6495 ! lipoprotein +intersection_of: has_input CHEBI:6495 +relationship: has_input CHEBI:6495 [Term] id: GO:0055103 @@ -107251,7 +93332,7 @@ namespace: biological_process def: "The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:dos] synonym: "glycinergic synaptic transmission" EXACT [] is_a: GO:0007268 ! chemical synaptic transmission -relationship: has_participant CHEBI:57305 ! glycine zwitterion +relationship: has_participant CHEBI:57305 [Term] id: GO:0060014 @@ -107696,6 +93777,8 @@ def: "The regulated release of serotonin by a cell, in which released serotonin synonym: "serotonin release, neurotransmission" RELATED [GOC:tb] is_a: GO:0001820 ! serotonin secretion is_a: GO:0007269 ! neurotransmitter secretion +intersection_of: GO:0007269 ! neurotransmitter secretion +intersection_of: has_primary_input CHEBI:350546 [Term] id: GO:0060113 @@ -108659,11 +94742,10 @@ namespace: biological_process alt_id: GO:1903717 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23509267] synonym: "response to ammonia" EXACT [] -is_a: GO:0010035 ! response to inorganic substance -is_a: GO:1901698 ! response to nitrogen compound +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:28938 ! ammonium -relationship: has_input CHEBI:28938 ! ammonium +intersection_of: has_input CHEBI:28938 +relationship: has_input CHEBI:28938 [Term] id: GO:0060363 @@ -109790,7 +95872,6 @@ name: regulation of peptide hormone processing namespace: biological_process def: "Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone." [GOC:dph, GOC:tb] is_a: GO:0032350 ! regulation of hormone metabolic process -is_a: GO:0034248 ! regulation of amide metabolic process is_a: GO:0070613 ! regulation of protein processing intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016486 ! peptide hormone processing @@ -109805,7 +95886,6 @@ namespace: biological_process def: "Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone." [GOC:dph, GOC:tb] is_a: GO:0010954 ! positive regulation of protein processing is_a: GO:0032352 ! positive regulation of hormone metabolic process -is_a: GO:0034250 ! positive regulation of amide metabolic process is_a: GO:0060568 ! regulation of peptide hormone processing intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016486 ! peptide hormone processing @@ -109820,7 +95900,6 @@ namespace: biological_process def: "Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone." [GOC:dph, GOC:tb] is_a: GO:0010955 ! negative regulation of protein processing is_a: GO:0032351 ! negative regulation of hormone metabolic process -is_a: GO:0034249 ! negative regulation of amide metabolic process is_a: GO:0060568 ! regulation of peptide hormone processing intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016486 ! peptide hormone processing @@ -109936,10 +96015,10 @@ name: multicellular organismal-level iron ion homeostasis namespace: biological_process def: "A chemical homeostatic process involved in the maintenance of a steady state level of iron within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell." [PMID:31431773] synonym: "multicellular organismal iron ion homeostasis" EXACT [] -is_a: GO:0055072 ! iron ion homeostasis -is_a: GO:0140962 ! multicellular organismal-level chemical homeostasis +is_a: GO:0048871 ! multicellular organismal-level homeostasis intersection_of: GO:0048871 ! multicellular organismal-level homeostasis -intersection_of: regulates_levels_of CHEBI:24875 ! iron cation +intersection_of: regulates_levels_of CHEBI:24875 +relationship: regulates_levels_of CHEBI:24875 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24554" xsd:anyURI created_by: dph creation_date: 2009-05-08T02:18:21Z @@ -110561,8 +96640,8 @@ def: "Binds to and stops, prevents or reduces the activity of deoxyribonuclease. synonym: "DNase inhibitor activity" RELATED [GOC:dph, GOC:tb] is_a: GO:0140721 ! nuclease inhibitor activity intersection_of: GO:0098772 ! molecular function regulator activity -intersection_of: directly_negatively_regulates GO:0004536 ! deoxyribonuclease activity -relationship: directly_negatively_regulates GO:0004536 ! deoxyribonuclease activity +intersection_of: directly_negatively_regulates GO:0004536 ! DNA nuclease activity +relationship: directly_negatively_regulates GO:0004536 ! DNA nuclease activity created_by: dph creation_date: 2009-06-08T03:00:35Z @@ -112551,6 +98630,7 @@ name: stomach neuroendocrine cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium." [GOC:dph, PMID:18173746] synonym: "gastric neuroendocrine cell differentiation" RELATED [GOC:dph] +is_a: GO:0035883 ! enteroendocrine cell differentiation is_a: GO:0061101 ! neuroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000222 ! stomach neuroendocrine cell @@ -114165,13 +100245,10 @@ id: GO:0061370 name: testosterone biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5." [GOC:dph, GOC:yaf] -is_a: GO:0006694 ! steroid biosynthetic process -is_a: GO:0042181 ! ketone biosynthetic process -is_a: GO:0120255 ! olefinic compound biosynthetic process -is_a: GO:1901617 ! organic hydroxy compound biosynthetic process +is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:17347 ! testosterone -relationship: has_primary_output CHEBI:17347 ! testosterone +intersection_of: has_primary_output CHEBI:17347 +relationship: has_primary_output CHEBI:17347 created_by: dph creation_date: 2010-10-27T02:50:48Z @@ -114567,7 +100644,7 @@ def: "The regulated release of acetylcholine by a cell." [GOC:dph] is_a: GO:0015870 ! acetylcholine transport is_a: GO:0023061 ! signal release intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:15355 ! acetylcholine +intersection_of: has_primary_input CHEBI:15355 created_by: dph creation_date: 2013-06-21T15:40:39Z @@ -114578,10 +100655,25 @@ namespace: biological_process def: "The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter." [GOC:dph] is_a: GO:0007269 ! neurotransmitter secretion is_a: GO:0099124 ! axonal dopamine secretion +intersection_of: GO:0007269 ! neurotransmitter secretion +intersection_of: has_primary_input CHEBI:59905 relationship: part_of GO:0001963 ! synaptic transmission, dopaminergic created_by: dph creation_date: 2013-06-21T15:43:15Z +[Term] +id: GO:0061529 +name: epinephrine secretion, neurotransmission +namespace: biological_process +def: "The regulated release of epinephrine by a cell in which the epinephrine acts as a neurotransmitter." [GOC:dph] +synonym: "adrenaline secretion, neurotransmission" EXACT [GOC:dph] +is_a: GO:0007269 ! neurotransmitter secretion +is_a: GO:0048242 ! epinephrine secretion +intersection_of: GO:0007269 ! neurotransmitter secretion +intersection_of: has_primary_input CHEBI:33568 +created_by: dph +creation_date: 2013-06-21T15:47:22Z + [Term] id: GO:0061533 name: norepinephrine secretion, neurotransmission @@ -114590,6 +100682,8 @@ def: "The regulated release of norepinephrine by a cell, in which the norepineph synonym: "noradrenaline secretion, neurotransmission" EXACT [GOC:dph] is_a: GO:0048243 ! norepinephrine secretion is_a: GO:0160043 ! catecholamine secretion, neurotransmission +intersection_of: GO:0007269 ! neurotransmitter secretion +intersection_of: has_primary_input CHEBI:72587 created_by: dph creation_date: 2013-06-21T16:05:08Z @@ -114600,6 +100694,8 @@ namespace: biological_process def: "The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter." [GOC:dph] is_a: GO:0007269 ! neurotransmitter secretion is_a: GO:0014051 ! gamma-aminobutyric acid secretion +intersection_of: GO:0007269 ! neurotransmitter secretion +intersection_of: has_primary_input CHEBI:59888 relationship: part_of GO:0051932 ! synaptic transmission, GABAergic created_by: dph creation_date: 2013-06-21T16:10:50Z @@ -114611,6 +100707,9 @@ namespace: biological_process def: "The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter." [GOC:dph] is_a: GO:0007269 ! neurotransmitter secretion is_a: GO:0014047 ! glutamate secretion +is_a: GO:0051938 ! L-glutamate import +intersection_of: GO:0007269 ! neurotransmitter secretion +intersection_of: has_primary_input CHEBI:29985 relationship: part_of GO:0035249 ! synaptic transmission, glutamatergic created_by: dph creation_date: 2013-06-21T16:14:47Z @@ -114623,7 +100722,7 @@ def: "The controlled release of glycine by a cell." [GOC:dph] is_a: GO:0015816 ! glycine transport is_a: GO:0032940 ! secretion by cell intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:57305 ! glycine zwitterion +intersection_of: has_primary_input CHEBI:57305 created_by: dph creation_date: 2013-06-21T16:18:23Z @@ -114634,6 +100733,8 @@ namespace: biological_process def: "The controlled release of glycine by a cell, in which glycine acts as a neurotransmitter." [GOC:dph] is_a: GO:0007269 ! neurotransmitter secretion is_a: GO:0061536 ! glycine secretion +intersection_of: GO:0007269 ! neurotransmitter secretion +intersection_of: has_primary_input CHEBI:57305 relationship: part_of GO:0060012 ! synaptic transmission, glycinergic created_by: dph creation_date: 2013-06-21T16:19:02Z @@ -114645,6 +100746,9 @@ namespace: biological_process def: "The controlled release of histamine by a cell, in which the histamine acts as a neurotransmitter." [GOC:dph] is_a: GO:0001821 ! histamine secretion is_a: GO:0007269 ! neurotransmitter secretion +intersection_of: GO:0007269 ! neurotransmitter secretion +intersection_of: has_primary_input CHEBI:57595 +relationship: has_primary_input CHEBI:57595 created_by: dph creation_date: 2013-06-21T16:21:21Z @@ -115040,8 +101144,8 @@ namespace: biological_process def: "Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds." [GOC:vw] is_a: GO:0098754 ! detoxification intersection_of: GO:0098754 ! detoxification -intersection_of: has_input CHEBI:24835 ! inorganic molecular entity -relationship: has_input CHEBI:24835 ! inorganic molecular entity +intersection_of: has_input CHEBI:24835 +relationship: has_input CHEBI:24835 created_by: dph creation_date: 2015-03-09T09:16:23Z @@ -115157,7 +101261,7 @@ def: "A process in which a calcium ion is transported from one side of a Golgi m is_a: GO:0032472 ! Golgi calcium ion transport is_a: GO:0070588 ! calcium ion transmembrane transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:29108 ! calcium(2+) +intersection_of: has_primary_input CHEBI:29108 intersection_of: results_in_transport_across GO:0016020 ! membrane intersection_of: results_in_transport_to_from_or_in GO:0005794 ! Golgi apparatus created_by: dph @@ -115480,16 +101584,6 @@ relationship: part_of GO:0019233 ! sensory perception of pain created_by: dph creation_date: 2019-09-13T13:48:47Z -[Term] -id: GO:0062197 -name: cellular response to chemical stress -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress." [PMID:26653712] -is_a: GO:0033554 ! cellular response to stress -is_a: GO:0070887 ! cellular response to chemical stimulus -created_by: dph -creation_date: 2019-12-10T14:42:03Z - [Term] id: GO:0062236 name: ionocyte differentiation @@ -115626,19 +101720,6 @@ intersection_of: GO:0031974 ! membrane-enclosed lumen intersection_of: part_of GO:0043229 ! intracellular organelle relationship: part_of GO:0043229 ! intracellular organelle -[Term] -id: GO:0070026 -name: nitric oxide binding -namespace: molecular_function -def: "Binding to nitric oxide (NO)." [GOC:ecd] -synonym: "nitrogen monoxide binding" EXACT [] -synonym: "nitrosyl binding" EXACT [CHEBI:16480] -synonym: "NO binding" EXACT [] -is_a: GO:0005488 ! binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:35196 ! nitrogen oxide -relationship: has_input CHEBI:35196 ! nitrogen oxide - [Term] id: GO:0070050 name: neuron cellular homeostasis @@ -115678,8 +101759,8 @@ namespace: biological_process def: "The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans)." [GOC:BHF, GOC:rl] is_a: GO:0030072 ! peptide hormone secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:5391 ! glucagon -relationship: has_primary_input CHEBI:5391 ! glucagon +intersection_of: has_primary_input CHEBI:5391 +relationship: has_primary_input CHEBI:5391 [Term] id: GO:0070092 @@ -116115,8 +102196,8 @@ namespace: biological_process def: "The regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:mah] is_a: GO:0030072 ! peptide hormone secretion intersection_of: GO:0046903 ! secretion -intersection_of: has_primary_input CHEBI:64628 ! somatostatin -relationship: has_primary_input CHEBI:64628 ! somatostatin +intersection_of: has_primary_input CHEBI:64628 +relationship: has_primary_input CHEBI:64628 [Term] id: GO:0070254 @@ -116487,10 +102568,10 @@ name: ammonium ion binding namespace: molecular_function def: "Binding to ammonium ions (NH4+)." [CHEBI:28938, GOC:ecd] synonym: "ammonium binding" RELATED [] -is_a: GO:0043169 ! cation binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:28938 ! ammonium -relationship: has_input CHEBI:28938 ! ammonium +intersection_of: has_input CHEBI:28938 +relationship: has_input CHEBI:28938 [Term] id: GO:0070444 @@ -116584,17 +102665,6 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000226 ! microtubule cytoskeleton organization relationship: regulates GO:0000226 ! microtubule cytoskeleton organization -[Term] -id: GO:0070542 -name: response to fatty acid -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus." [GOC:lp] -is_a: GO:0033993 ! response to lipid -is_a: GO:1901700 ! response to oxygen-containing compound -intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:28868 ! fatty acid anion -relationship: has_input CHEBI:28868 ! fatty acid anion - [Term] id: GO:0070560 name: protein secretion by platelet @@ -116619,10 +102689,9 @@ comment: Note that this term is not intended for use in annotating lateral movem synonym: "calcium ion membrane transport" EXACT [] synonym: "transmembrane calcium transport" EXACT [GOC:mah] is_a: GO:0006816 ! calcium ion transport -is_a: GO:0098655 ! monoatomic cation transmembrane transport -is_a: GO:0098662 ! inorganic cation transmembrane transport +is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0055085 ! transmembrane transport -intersection_of: has_primary_input CHEBI:29108 ! calcium(2+) +intersection_of: has_primary_input CHEBI:29108 created_by: mah creation_date: 2009-04-28T10:44:09Z @@ -116659,10 +102728,9 @@ name: transepithelial ammonium transport namespace: biological_process def: "The directed movement of ammonium ions from one side of an epithelium to the other." [GOC:mah, GOC:yaf] is_a: GO:0070633 ! transepithelial transport -is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0070633 ! transepithelial transport -intersection_of: has_primary_input CHEBI:28938 ! ammonium -relationship: has_primary_input CHEBI:28938 ! ammonium +intersection_of: has_primary_input CHEBI:28938 +relationship: has_primary_input CHEBI:28938 created_by: mah creation_date: 2009-05-06T03:34:43Z @@ -116929,7 +102997,6 @@ name: regulation of glycogen metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah] synonym: "regulation of glycogen metabolism" EXACT [GOC:mah] -is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process is_a: GO:0032881 ! regulation of polysaccharide metabolic process is_a: GO:0043467 ! regulation of generation of precursor metabolites and energy intersection_of: GO:0065007 ! biological regulation @@ -116945,7 +103012,8 @@ namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah] synonym: "negative regulation of glycogen metabolism" EXACT [GOC:mah] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process -is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0005977 ! glycogen metabolic process @@ -116961,6 +103029,7 @@ def: "Any process that activates or increases the frequency, rate or extent of t synonym: "positive regulation of glycogen metabolism" EXACT [GOC:mah] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0010907 ! positive regulation of glucose metabolic process +is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0005977 ! glycogen metabolic process @@ -117168,10 +103237,9 @@ namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups." [GOC:mah] synonym: "cellular response to amino acid" EXACT [GOC:mah] is_a: GO:0043200 ! response to amino acid -is_a: GO:0071417 ! cellular response to organonitrogen compound -is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:33709 ! amino acid +intersection_of: has_input CHEBI:33709 created_by: mah creation_date: 2009-12-03T02:08:11Z @@ -117193,39 +103261,12 @@ alt_id: GO:1903718 def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23509267] synonym: "cellular response to ammonia" EXACT [] is_a: GO:0060359 ! response to ammonium ion -is_a: GO:1901699 ! cellular response to nitrogen compound +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:28938 ! ammonium +intersection_of: has_input CHEBI:28938 created_by: mah creation_date: 2009-12-03T02:39:40Z -[Term] -id: GO:0071248 -name: cellular response to metal ion -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus." [GOC:mah] -synonym: "cellular response to heavy metal" NARROW [GOC:mah] -synonym: "cellular response to metal" EXACT [GOC:mah] -is_a: GO:0010038 ! response to metal ion -is_a: GO:0071241 ! cellular response to inorganic substance -intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:25213 ! metal cation -created_by: mah -creation_date: 2009-12-03T02:46:31Z - -[Term] -id: GO:0071277 -name: cellular response to calcium ion -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus." [GOC:mah] -synonym: "cellular response to Ca2+ ion" EXACT [GOC:mah] -is_a: GO:0051592 ! response to calcium ion -is_a: GO:0071248 ! cellular response to metal ion -intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:39124 ! calcium ion -created_by: mah -creation_date: 2009-12-10T03:55:01Z - [Term] id: GO:0071281 name: cellular response to iron ion @@ -117233,9 +103274,9 @@ namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus." [GOC:mah] synonym: "cellular response to iron" EXACT [GOC:mah] is_a: GO:0010039 ! response to iron ion -is_a: GO:0071248 ! cellular response to metal ion +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:24875 ! iron cation +intersection_of: has_input CHEBI:24875 created_by: mah creation_date: 2009-12-10T03:57:22Z @@ -117249,31 +103290,6 @@ is_a: GO:0070887 ! cellular response to chemical stimulus created_by: mah creation_date: 2009-12-10T04:46:04Z -[Term] -id: GO:0071311 -name: cellular response to acetate -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus." [GOC:mah] -is_a: GO:0010034 ! response to acetate -is_a: GO:0071310 ! cellular response to organic substance -is_a: GO:1901701 ! cellular response to oxygen-containing compound -intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:30089 ! acetate -created_by: mah -creation_date: 2009-12-10T04:48:16Z - -[Term] -id: GO:0071312 -name: cellular response to alkaloid -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active." [GOC:mah] -is_a: GO:0043279 ! response to alkaloid -is_a: GO:0071417 ! cellular response to organonitrogen compound -intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:22315 ! alkaloid -created_by: mah -creation_date: 2009-12-10T04:50:58Z - [Term] id: GO:0071322 name: cellular response to carbohydrate stimulus @@ -117281,33 +103297,20 @@ namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus." [GOC:mah] is_a: GO:0009743 ! response to carbohydrate is_a: GO:0071310 ! cellular response to organic substance -is_a: GO:1901701 ! cellular response to oxygen-containing compound intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:16646 ! carbohydrate +intersection_of: has_input CHEBI:16646 created_by: mah creation_date: 2009-12-10T05:13:33Z -[Term] -id: GO:0071326 -name: cellular response to monosaccharide stimulus -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus." [GOC:mah] -is_a: GO:0034284 ! response to monosaccharide -is_a: GO:0071322 ! cellular response to carbohydrate stimulus -intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:35381 ! monosaccharide -created_by: mah -creation_date: 2009-12-10T05:27:18Z - [Term] id: GO:0071331 name: cellular response to hexose stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus." [GOC:mah] is_a: GO:0009746 ! response to hexose -is_a: GO:0071326 ! cellular response to monosaccharide stimulus +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:18133 ! hexose +intersection_of: has_input CHEBI:18133 created_by: mah creation_date: 2009-12-10T05:37:00Z @@ -117318,9 +103321,9 @@ namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus." [GOC:mah] is_a: GO:0001678 ! intracellular glucose homeostasis is_a: GO:0009749 ! response to glucose -is_a: GO:0071331 ! cellular response to hexose stimulus +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:17234 ! glucose +intersection_of: has_input CHEBI:17234 created_by: mah creation_date: 2009-12-10T05:38:03Z @@ -117341,9 +103344,9 @@ namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals." [GOC:mah] synonym: "cellular response to polypeptide hormone stimulus" EXACT [GOC:mah] is_a: GO:0043434 ! response to peptide hormone -is_a: GO:1901653 ! cellular response to peptide +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:25905 ! peptide hormone +intersection_of: has_input CHEBI:25905 created_by: mah creation_date: 2009-12-11T03:24:18Z @@ -117353,9 +103356,9 @@ name: cellular response to glucagon stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus." [GOC:mah] is_a: GO:0033762 ! response to glucagon -is_a: GO:0071375 ! cellular response to peptide hormone stimulus +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:5391 ! glucagon +intersection_of: has_input CHEBI:5391 created_by: mah creation_date: 2009-12-11T03:25:07Z @@ -117365,10 +103368,9 @@ name: cellular response to steroid hormone stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus." [GOC:mah] is_a: GO:0048545 ! response to steroid hormone -is_a: GO:0071396 ! cellular response to lipid -is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:26764 ! steroid hormone +intersection_of: has_input CHEBI:26764 created_by: mah creation_date: 2009-12-11T03:49:02Z @@ -117377,11 +103379,10 @@ id: GO:0071384 name: cellular response to corticosteroid stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids." [GOC:mah] -is_a: GO:0031960 ! response to corticosteroid -is_a: GO:0071383 ! cellular response to steroid hormone stimulus +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:36699 ! corticosteroid hormone -relationship: has_input CHEBI:36699 ! corticosteroid hormone +intersection_of: has_input CHEBI:36699 +relationship: has_input CHEBI:36699 created_by: mah creation_date: 2009-12-11T03:52:07Z @@ -117391,9 +103392,9 @@ name: cellular response to glucocorticoid stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects." [GOC:mah] is_a: GO:0051384 ! response to glucocorticoid -is_a: GO:0071384 ! cellular response to corticosteroid stimulus +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:24261 ! glucocorticoid +intersection_of: has_input CHEBI:24261 created_by: mah creation_date: 2009-12-11T03:53:56Z @@ -117403,9 +103404,9 @@ name: cellular response to mineralocorticoid stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance." [GOC:mah] is_a: GO:0051385 ! response to mineralocorticoid -is_a: GO:0071384 ! cellular response to corticosteroid stimulus +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:25354 ! mineralocorticoid +intersection_of: has_input CHEBI:25354 created_by: mah creation_date: 2009-12-11T03:59:02Z @@ -117416,11 +103417,9 @@ namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen." [GOC:mah] synonym: "cellular response to E2 stimulus" EXACT [GOC:mah] is_a: GO:0032355 ! response to estradiol -is_a: GO:0071396 ! cellular response to lipid -is_a: GO:0071407 ! cellular response to organic cyclic compound -is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:23965 ! estradiol +intersection_of: has_input CHEBI:23965 created_by: mah creation_date: 2009-12-11T04:10:31Z @@ -117430,10 +103429,9 @@ name: cellular response to progesterone stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus." [GOC:mah] is_a: GO:0032570 ! response to progesterone -is_a: GO:0071383 ! cellular response to steroid hormone stimulus -is_a: GO:1901655 ! cellular response to ketone +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:17026 ! progesterone +intersection_of: has_input CHEBI:17026 created_by: mah creation_date: 2009-12-11T04:11:13Z @@ -117443,11 +103441,9 @@ name: cellular response to testosterone stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus." [GOC:mah] is_a: GO:0033574 ! response to testosterone -is_a: GO:0071396 ! cellular response to lipid -is_a: GO:0071407 ! cellular response to organic cyclic compound -is_a: GO:1901655 ! cellular response to ketone +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:17347 ! testosterone +intersection_of: has_input CHEBI:17347 created_by: mah creation_date: 2009-12-11T04:11:29Z @@ -117459,23 +103455,10 @@ def: "Any process that results in a change in state or activity of a cell (in te is_a: GO:0033993 ! response to lipid is_a: GO:0071310 ! cellular response to organic substance intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:18059 ! lipid +intersection_of: has_input CHEBI:18059 created_by: mah creation_date: 2009-12-11T04:37:10Z -[Term] -id: GO:0071398 -name: cellular response to fatty acid -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus." [GOC:mah] -is_a: GO:0070542 ! response to fatty acid -is_a: GO:0071396 ! cellular response to lipid -is_a: GO:1901701 ! cellular response to oxygen-containing compound -intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:28868 ! fatty acid anion -created_by: mah -creation_date: 2009-12-11T04:39:56Z - [Term] id: GO:0071402 name: cellular response to lipoprotein particle stimulus @@ -117497,7 +103480,7 @@ synonym: "cellular response to organic cyclic substance" EXACT [GOC:mah] is_a: GO:0014070 ! response to organic cyclic compound is_a: GO:0071310 ! cellular response to organic substance intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:33832 ! organic cyclic compound +intersection_of: has_input CHEBI:33832 created_by: mah creation_date: 2009-12-14T02:55:58Z @@ -117510,9 +103493,8 @@ synonym: "cellular response to organic nitrogen" EXACT [GOC:mah] is_a: GO:0010243 ! response to organonitrogen compound is_a: GO:0071310 ! cellular response to organic substance is_a: GO:0071495 ! cellular response to endogenous stimulus -is_a: GO:1901699 ! cellular response to nitrogen compound intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:35352 ! organonitrogen compound +intersection_of: has_input CHEBI:35352 created_by: mah creation_date: 2009-12-14T04:07:27Z @@ -117522,9 +103504,9 @@ name: cellular response to amine stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." [GOC:mah] is_a: GO:0014075 ! response to amine -is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:32952 ! amine +intersection_of: has_input CHEBI:32952 created_by: mah creation_date: 2009-12-14T04:08:17Z @@ -117535,9 +103517,9 @@ namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter." [GOC:mah] synonym: "cellular response to histamine stimulus" EXACT [GOC:mah] is_a: GO:0034776 ! response to histamine -is_a: GO:1901699 ! cellular response to nitrogen compound +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:58432 ! histaminium +intersection_of: has_input CHEBI:58432 created_by: mah creation_date: 2009-12-14T04:09:25Z @@ -117555,27 +103537,15 @@ relationship: part_of GO:0030097 ! hemopoiesis created_by: mah creation_date: 2009-12-16T10:22:52Z -[Term] -id: GO:0071450 -name: cellular response to oxygen radical -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion." [GOC:mah] -is_a: GO:0000305 ! response to oxygen radical -is_a: GO:0034614 ! cellular response to reactive oxygen species -intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:61073 ! oxygen radical -created_by: mah -creation_date: 2009-12-16T04:38:52Z - [Term] id: GO:0071451 name: cellular response to superoxide namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion." [GOC:mah] is_a: GO:0000303 ! response to superoxide -is_a: GO:0071450 ! cellular response to oxygen radical +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:18421 ! superoxide +intersection_of: has_input CHEBI:18421 created_by: mah creation_date: 2009-12-16T04:39:14Z @@ -117588,7 +103558,7 @@ is_a: GO:0009415 ! response to water is_a: GO:0071214 ! cellular response to abiotic stimulus is_a: GO:1901701 ! cellular response to oxygen-containing compound intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:15377 ! water +intersection_of: has_input CHEBI:15377 created_by: mah creation_date: 2009-12-18T11:32:44Z @@ -117936,8 +103906,8 @@ namespace: biological_process def: "The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon." [GOC:mah] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:50860 ! organic molecular entity -relationship: has_primary_input CHEBI:50860 ! organic molecular entity +intersection_of: has_primary_input CHEBI:50860 +relationship: has_primary_input CHEBI:50860 created_by: mah creation_date: 2010-03-08T02:15:14Z @@ -117951,8 +103921,8 @@ synonym: "organic molecular entity metabolism" EXACT [] synonym: "organic substance metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:50860 ! organic molecular entity -relationship: has_primary_input_or_output CHEBI:50860 ! organic molecular entity +intersection_of: has_primary_input_or_output CHEBI:50860 +relationship: has_primary_input_or_output CHEBI:50860 created_by: mah creation_date: 2010-03-08T03:32:18Z @@ -117963,8 +103933,8 @@ namespace: biological_process def: "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:51143 ! nitrogen molecular entity -relationship: has_primary_input CHEBI:51143 ! nitrogen molecular entity +intersection_of: has_primary_input CHEBI:51143 +relationship: has_primary_input CHEBI:51143 created_by: mah creation_date: 2010-03-08T03:56:28Z @@ -118038,12 +104008,10 @@ id: GO:0071731 name: response to nitric oxide namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus." [GOC:mah, GOC:yaf] -is_a: GO:0010035 ! response to inorganic substance -is_a: GO:1901698 ! response to nitrogen compound -is_a: GO:1901700 ! response to oxygen-containing compound +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:16480 ! nitric oxide -relationship: has_input CHEBI:16480 ! nitric oxide +intersection_of: has_input CHEBI:16480 +relationship: has_input CHEBI:16480 created_by: mah creation_date: 2010-03-17T04:03:38Z @@ -118054,10 +104022,8 @@ namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus." [GOC:mah, GOC:yaf] is_a: GO:0071241 ! cellular response to inorganic substance is_a: GO:0071731 ! response to nitric oxide -is_a: GO:1901701 ! cellular response to oxygen-containing compound -is_a: GO:1902170 ! cellular response to reactive nitrogen species intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:16480 ! nitric oxide +intersection_of: has_input CHEBI:16480 created_by: mah creation_date: 2010-03-17T04:12:52Z @@ -118228,7 +104194,7 @@ synonym: "protein membrane transport" EXACT [] is_a: GO:0015031 ! protein transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:36080 ! protein +intersection_of: has_primary_input CHEBI:36080 intersection_of: results_in_transport_across GO:0016020 ! membrane created_by: mah creation_date: 2010-09-03T02:54:26Z @@ -118303,43 +104269,16 @@ is_a: GO:0009987 ! cellular process created_by: mah creation_date: 2010-09-10T01:39:16Z -[Term] -id: GO:0071867 -name: response to monoamine -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." [GOC:mah] -synonym: "response to monoamine stimulus" EXACT [GOC:dos] -is_a: GO:0010243 ! response to organonitrogen compound -intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:63534 ! monoamine -relationship: has_input CHEBI:63534 ! monoamine -created_by: mah -creation_date: 2010-09-13T02:36:37Z - -[Term] -id: GO:0071868 -name: cellular response to monoamine stimulus -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." [GOC:mah] -is_a: GO:0071417 ! cellular response to organonitrogen compound -is_a: GO:0071867 ! response to monoamine -intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:63534 ! monoamine -created_by: mah -creation_date: 2010-09-13T02:38:52Z - [Term] id: GO:0071869 name: response to catecholamine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." [GOC:BHF, GOC:mah] synonym: "response to catecholamine stimulus" EXACT [GOC:dos] -is_a: GO:0014070 ! response to organic cyclic compound -is_a: GO:0071867 ! response to monoamine -is_a: GO:1901700 ! response to oxygen-containing compound +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:33567 ! catecholamine -relationship: has_input CHEBI:33567 ! catecholamine +intersection_of: has_input CHEBI:33567 +relationship: has_input CHEBI:33567 created_by: mah creation_date: 2010-09-13T02:51:13Z @@ -118348,12 +104287,10 @@ id: GO:0071870 name: cellular response to catecholamine stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." [GOC:BHF, GOC:mah] -is_a: GO:0071407 ! cellular response to organic cyclic compound -is_a: GO:0071868 ! cellular response to monoamine stimulus +is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:0071869 ! response to catecholamine -is_a: GO:1901701 ! cellular response to oxygen-containing compound intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:33567 ! catecholamine +intersection_of: has_input CHEBI:33567 created_by: mah creation_date: 2010-09-13T02:54:50Z @@ -118365,10 +104302,10 @@ def: "Any process that results in a change in state or activity of a cell or an comment: Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors. synonym: "response to adrenaline stimulus" EXACT [GOC:mah] synonym: "response to epinephrine stimulus" EXACT [GOC:dos] -is_a: GO:0071869 ! response to catecholamine +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:33568 ! adrenaline -relationship: has_input CHEBI:33568 ! adrenaline +intersection_of: has_input CHEBI:33568 +relationship: has_input CHEBI:33568 created_by: mah creation_date: 2010-09-13T03:27:48Z @@ -118379,10 +104316,10 @@ namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system." [GOC:BHF, GOC:mah] comment: Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors. synonym: "cellular response to adrenaline stimulus" EXACT [GOC:mah] -is_a: GO:0071870 ! cellular response to catecholamine stimulus +is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:0071871 ! response to epinephrine intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:33568 ! adrenaline +intersection_of: has_input CHEBI:33568 created_by: mah creation_date: 2010-09-13T03:31:40Z @@ -118394,11 +104331,10 @@ def: "Any process that results in a change in state or activity of a cell or an comment: Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors. synonym: "response to noradrenaline stimulus" EXACT [GOC:mah] synonym: "response to norepinephrine stimulus" EXACT [GOC:dos] -is_a: GO:0010033 ! response to organic substance -is_a: GO:1901698 ! response to nitrogen compound +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:72587 ! (R)-noradrenaline(1+) -relationship: has_input CHEBI:72587 ! (R)-noradrenaline(1+) +intersection_of: has_input CHEBI:72587 +relationship: has_input CHEBI:72587 created_by: mah creation_date: 2010-09-13T03:31:53Z @@ -118409,10 +104345,10 @@ namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system." [GOC:BHF, GOC:mah] comment: Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors. synonym: "cellular response to noradrenaline stimulus" EXACT [GOC:mah] +is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:0071873 ! response to norepinephrine -is_a: GO:1901699 ! cellular response to nitrogen compound intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:72587 ! (R)-noradrenaline(1+) +intersection_of: has_input CHEBI:72587 created_by: mah creation_date: 2010-09-13T03:33:32Z @@ -118457,10 +104393,10 @@ namespace: molecular_function def: "Binding to bicarbonate ions (CHO3-)." [GOC:curators] synonym: "CHO3- ion binding binding" EXACT [] synonym: "hydrogencarbonate binding" EXACT [CHEBI:17544] -is_a: GO:0043168 ! anion binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:17544 ! hydrogencarbonate -relationship: has_input CHEBI:17544 ! hydrogencarbonate +intersection_of: has_input CHEBI:17544 +relationship: has_input CHEBI:17544 created_by: mah creation_date: 2010-09-14T01:47:43Z @@ -118486,11 +104422,10 @@ synonym: "DNA biosynthesis" EXACT [GOC:mah] synonym: "DNA formation" EXACT [GOC:mah] synonym: "DNA synthesis" EXACT [GOC:mah] is_a: GO:0006259 ! DNA metabolic process -is_a: GO:0009059 ! macromolecule biosynthetic process -is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process +is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:16991 ! deoxyribonucleic acid -relationship: has_primary_output CHEBI:16991 ! deoxyribonucleic acid +intersection_of: has_primary_output CHEBI:16991 +relationship: has_primary_output CHEBI:16991 created_by: mah creation_date: 2010-09-15T02:14:33Z @@ -118550,7 +104485,7 @@ creation_date: 2010-09-30T05:21:03Z id: GO:0071944 name: cell periphery namespace: cellular_component -def: "The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures." [GOC:mah] +def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] subset: goslim_flybase_ribbon is_a: GO:0110165 ! cellular anatomical entity created_by: mah @@ -121291,11 +107226,11 @@ id: GO:0072329 name: monocarboxylic acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group." [GOC:mah] +is_a: GO:0009056 ! catabolic process is_a: GO:0032787 ! monocarboxylic acid metabolic process -is_a: GO:0046395 ! carboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:35757 ! monocarboxylic acid anion -relationship: has_primary_input CHEBI:35757 ! monocarboxylic acid anion +intersection_of: has_primary_input CHEBI:35757 +relationship: has_primary_input CHEBI:35757 created_by: mah creation_date: 2010-11-02T04:41:55Z @@ -121311,8 +107246,8 @@ synonym: "monocarboxylic acid synthesis" EXACT [GOC:mah] is_a: GO:0032787 ! monocarboxylic acid metabolic process is_a: GO:0046394 ! carboxylic acid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:35757 ! monocarboxylic acid anion -relationship: has_primary_output CHEBI:35757 ! monocarboxylic acid anion +intersection_of: has_primary_output CHEBI:35757 +relationship: has_primary_output CHEBI:35757 created_by: mah creation_date: 2010-11-02T04:51:32Z @@ -121322,11 +107257,10 @@ name: modified amino acid transport namespace: biological_process def: "The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "amino acid derivative transport" EXACT [] -is_a: GO:0071702 ! organic substance transport -is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:83821 ! amino acid derivative -relationship: has_primary_input CHEBI:83821 ! amino acid derivative +intersection_of: has_primary_input CHEBI:83821 +relationship: has_primary_input CHEBI:83821 created_by: mah creation_date: 2010-11-04T12:18:23Z @@ -121338,8 +107272,8 @@ def: "Binding to a modified amino acid." [GOC:mah] synonym: "amino acid derivative binding" EXACT [] is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:83821 ! amino acid derivative -relationship: has_input CHEBI:83821 ! amino acid derivative +intersection_of: has_input CHEBI:83821 +relationship: has_input CHEBI:83821 created_by: mah creation_date: 2010-11-04T05:45:32Z @@ -121355,19 +107289,6 @@ relationship: acts_on_population_of CL:0002410 ! pancreatic stellate cell created_by: mah creation_date: 2010-11-05T03:04:50Z -[Term] -id: GO:0072348 -name: sulfur compound transport -namespace: biological_process -def: "The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] -synonym: "sulfur-containing compound transport" EXACT [GOC:mah] -is_a: GO:0006810 ! transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:26835 ! sulfur molecular entity -relationship: has_primary_input CHEBI:26835 ! sulfur molecular entity -created_by: mah -creation_date: 2010-11-11T11:43:56Z - [Term] id: GO:0072349 name: modified amino acid transmembrane transporter activity @@ -121377,8 +107298,8 @@ synonym: "amino acid derivative transmembrane transporter activity" EXACT [] synonym: "modified amino acid transporter activity" BROAD [GOC:mah] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:83821 ! amino acid derivative -relationship: has_primary_input CHEBI:83821 ! amino acid derivative +intersection_of: has_primary_input CHEBI:83821 +relationship: has_primary_input CHEBI:83821 relationship: part_of GO:0072337 ! modified amino acid transport created_by: mah creation_date: 2010-11-11T11:50:31Z @@ -121435,12 +107356,11 @@ comment: Note that this term is not intended for use in annotating lateral movem synonym: "ammonia transport" BROAD [] synonym: "ammonium membrane transport" EXACT [] synonym: "ammonium transport" BROAD [] -is_a: GO:0071705 ! nitrogen compound transport -is_a: GO:0098662 ! inorganic cation transmembrane transport +is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:28938 ! ammonium +intersection_of: has_primary_input CHEBI:28938 intersection_of: results_in_transport_across GO:0016020 ! membrane -relationship: has_primary_input CHEBI:28938 ! ammonium +relationship: has_primary_input CHEBI:28938 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22228" xsd:anyURI created_by: mah creation_date: 2010-12-10T10:29:57Z @@ -121591,25 +107511,11 @@ synonym: "diatomic oxygen metabolic process" EXACT [CHEBI:33263] synonym: "oxygen metabolism" EXACT [GOC:mah] is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:15379 ! dioxygen -relationship: has_primary_input_or_output CHEBI:15379 ! dioxygen +intersection_of: has_primary_input_or_output CHEBI:15379 +relationship: has_primary_input_or_output CHEBI:15379 created_by: mah creation_date: 2011-02-11T10:46:51Z -[Term] -id: GO:0072593 -name: reactive oxygen species metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers." [GOC:mah] -synonym: "reactive oxygen species metabolism" EXACT [GOC:mah] -synonym: "ROS metabolic process" EXACT [CHEBI:26523, GOC:mah] -is_a: GO:0044237 ! cellular metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:26523 ! reactive oxygen species -relationship: has_primary_input_or_output CHEBI:26523 ! reactive oxygen species -created_by: mah -creation_date: 2011-02-11T10:50:06Z - [Term] id: GO:0072594 name: establishment of protein localization to organelle @@ -121899,19 +107805,6 @@ relationship: regulates GO:0006950 ! response to stress created_by: dhl creation_date: 2009-05-06T04:51:28Z -[Term] -id: GO:0080135 -name: regulation of cellular response to stress -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:dhl] -is_a: GO:0050794 ! regulation of cellular process -is_a: GO:0080134 ! regulation of response to stress -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0033554 ! cellular response to stress -relationship: regulates GO:0033554 ! cellular response to stress -created_by: dhl -creation_date: 2009-05-06T05:02:52Z - [Term] id: GO:0080144 name: intracellular amino acid homeostasis @@ -121921,8 +107814,8 @@ synonym: "amino acid homeostasis" BROAD [] synonym: "cellular amino acid homeostasis" EXACT [] is_a: GO:0055082 ! intracellular chemical homeostasis intersection_of: GO:0055082 ! intracellular chemical homeostasis -intersection_of: regulates_levels_of CHEBI:33709 ! amino acid -relationship: regulates_levels_of CHEBI:33709 ! amino acid +intersection_of: regulates_levels_of CHEBI:33709 +relationship: regulates_levels_of CHEBI:33709 created_by: dhl creation_date: 2010-01-27T04:47:27Z @@ -121943,7 +107836,7 @@ id: GO:0080164 name: regulation of nitric oxide metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water." [GOC:DHL] -is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046209 ! nitric oxide metabolic process relationship: regulates GO:0046209 ! nitric oxide metabolic process @@ -122434,6 +108327,17 @@ relationship: part_of GO:0003015 ! heart process created_by: bf creation_date: 2012-03-19T01:28:23Z +[Term] +id: GO:0089709 +name: L-histidine transmembrane transport +namespace: biological_process +def: "The directed movement of L-histidine across a membrane." [PMID:21307582] +is_a: GO:0055085 ! transmembrane transport +intersection_of: GO:0006810 ! transport +intersection_of: has_primary_input CHEBI:57595 +intersection_of: results_in_transport_across GO:0016020 ! membrane +relationship: has_primary_input CHEBI:57595 + [Term] id: GO:0090009 name: primitive streak formation @@ -122709,7 +108613,7 @@ name: pancreatic epsilon cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic epsilon cell. A pancreatic epsilon cell is a cell in the pancreas that secretes ghrelin." [GOC:dph, GOC:tb] synonym: "pancreatic E cell differentiation" EXACT [] -is_a: GO:0030154 ! cell differentiation +is_a: GO:0035883 ! enteroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0005019 ! pancreatic epsilon cell relationship: part_of GO:0031018 ! endocrine pancreas development @@ -122722,7 +108626,7 @@ id: GO:0090105 name: pancreatic E cell development namespace: biological_process def: "The process whose specific outcome is the progression of a pancreatic E cell over time, from its formation to the mature structure." [GOC:dph, GOC:tb] -is_a: GO:0048468 ! cell development +is_a: GO:0002068 ! glandular epithelial cell development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0005019 ! pancreatic epsilon cell relationship: part_of GO:0090104 ! pancreatic epsilon cell differentiation @@ -122785,69 +108689,6 @@ intersection_of: has_target_end_location GO:0016020 ! membrane created_by: tb creation_date: 2009-12-08T03:18:51Z -[Term] -id: GO:0090153 -name: regulation of sphingolipid biosynthetic process -namespace: biological_process -def: "Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [GOC:ascb_2009, GOC:dph, GOC:tb] -is_a: GO:0010556 ! regulation of macromolecule biosynthetic process -is_a: GO:0031326 ! regulation of cellular biosynthetic process -is_a: GO:0044087 ! regulation of cellular component biogenesis -is_a: GO:0046890 ! regulation of lipid biosynthetic process -is_a: GO:0051171 ! regulation of nitrogen compound metabolic process -is_a: GO:1905038 ! regulation of membrane lipid metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0030148 ! sphingolipid biosynthetic process -relationship: regulates GO:0030148 ! sphingolipid biosynthetic process -created_by: tb -creation_date: 2009-12-08T03:25:49Z - -[Term] -id: GO:0090154 -name: positive regulation of sphingolipid biosynthetic process -namespace: biological_process -def: "Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [GOC:ascb_2009, GOC:dph, GOC:tb] -is_a: GO:0031328 ! positive regulation of cellular biosynthetic process -is_a: GO:0046889 ! positive regulation of lipid biosynthetic process -is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process -is_a: GO:0090153 ! regulation of sphingolipid biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0030148 ! sphingolipid biosynthetic process -relationship: positively_regulates GO:0030148 ! sphingolipid biosynthetic process -created_by: tb -creation_date: 2009-12-08T03:27:33Z - -[Term] -id: GO:0090155 -name: negative regulation of sphingolipid biosynthetic process -namespace: biological_process -alt_id: GO:0090157 -def: "Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [GOC:ascb_2009, GOC:dph, GOC:tb] -synonym: "negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis" RELATED [] -is_a: GO:0031327 ! negative regulation of cellular biosynthetic process -is_a: GO:0051055 ! negative regulation of lipid biosynthetic process -is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process -is_a: GO:0090153 ! regulation of sphingolipid biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0030148 ! sphingolipid biosynthetic process -relationship: negatively_regulates GO:0030148 ! sphingolipid biosynthetic process -created_by: tb -creation_date: 2009-12-08T03:33:39Z - -[Term] -id: GO:0090156 -name: intracellular sphingolipid homeostasis -namespace: biological_process -def: "A homeostatic process involved in the maintenance of a steady state level of sphingolipids within a cell." [GOC:ascb_2009, GOC:dph, GOC:tb] -synonym: "cellular sphingolipid homeostasis" EXACT [] -is_a: GO:0055082 ! intracellular chemical homeostasis -is_a: GO:0055088 ! lipid homeostasis -intersection_of: GO:0019725 ! cellular homeostasis -intersection_of: regulates_levels_of CHEBI:26739 ! sphingolipid -relationship: regulates_levels_of CHEBI:26739 ! sphingolipid -created_by: tb -creation_date: 2009-12-08T08:21:36Z - [Term] id: GO:0090162 name: establishment of epithelial cell polarity @@ -123246,11 +109087,10 @@ id: GO:0090304 name: nucleic acid metabolic process namespace: biological_process def: "Any cellular metabolic process involving nucleic acids." [GOC:dph, GOC:tb] -is_a: GO:0006139 ! nucleobase-containing compound metabolic process -is_a: GO:0043170 ! macromolecule metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:33696 ! nucleic acid -relationship: has_primary_input_or_output CHEBI:33696 ! nucleic acid +intersection_of: has_primary_input_or_output CHEBI:33696 +relationship: has_primary_input_or_output CHEBI:33696 created_by: tb creation_date: 2010-04-07T10:18:47Z @@ -123288,7 +109128,7 @@ name: regulation of superoxide metabolic process namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of superoxide metabolism, the chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species." [GOC:tb] synonym: "regulation of superoxide metabolism" EXACT [GOC:tb] -is_a: GO:2000377 ! regulation of reactive oxygen species metabolic process +is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006801 ! superoxide metabolic process relationship: regulates GO:0006801 ! superoxide metabolic process @@ -123408,10 +109248,10 @@ namespace: biological_process def: "A homeostatic process involved in the maintenance of a steady state level of glutamate within a cell." [GOC:tb] synonym: "cellular glutamate homeostasis" EXACT [] synonym: "glutamate homeostasis" EXACT [] -is_a: GO:0055082 ! intracellular chemical homeostasis +is_a: GO:0019725 ! cellular homeostasis intersection_of: GO:0019725 ! cellular homeostasis -intersection_of: regulates_levels_of CHEBI:14321 ! glutamate(1-) -relationship: regulates_levels_of CHEBI:14321 ! glutamate(1-) +intersection_of: regulates_levels_of CHEBI:14321 +relationship: regulates_levels_of CHEBI:14321 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24220" xsd:anyURI created_by: tb creation_date: 2012-09-24T14:22:02Z @@ -123422,11 +109262,12 @@ name: catecholamine uptake namespace: biological_process def: "The directed movement of catecholamine into a cell." [GOC:dph, GOC:tb] is_a: GO:0051937 ! catecholamine transport -is_a: GO:0098657 ! import into cell intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:33567 ! catecholamine +intersection_of: has_primary_input CHEBI:33567 intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure intersection_of: has_target_start_location GO:0005576 ! extracellular region +relationship: has_target_end_location GO:0005622 ! intracellular anatomical structure +relationship: has_target_start_location GO:0005576 ! extracellular region created_by: tb creation_date: 2012-10-17T11:06:17Z @@ -123436,11 +109277,12 @@ name: dopamine uptake namespace: biological_process def: "The directed movement of dopamine into a cell." [GOC:dph, GOC:tb] is_a: GO:0015872 ! dopamine transport -is_a: GO:0098657 ! import into cell intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:59905 ! dopaminium(1+) +intersection_of: has_primary_input CHEBI:59905 intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure intersection_of: has_target_start_location GO:0005576 ! extracellular region +relationship: has_target_end_location GO:0005622 ! intracellular anatomical structure +relationship: has_target_start_location GO:0005576 ! extracellular region created_by: tb creation_date: 2012-10-17T11:12:09Z @@ -123693,6 +109535,22 @@ relationship: occurs_in CL:0000169 ! type B pancreatic cell created_by: pr creation_date: 2011-05-04T02:24:38Z +[Term] +id: GO:0097054 +name: L-glutamate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid." [GOC:yaf] +synonym: "L-glutamate anabolism" EXACT [] +synonym: "L-glutamate biosynthesis" EXACT [] +synonym: "L-glutamate formation" EXACT [] +synonym: "L-glutamate synthesis" EXACT [] +is_a: GO:0006537 ! glutamate biosynthetic process +intersection_of: GO:0008152 ! metabolic process +intersection_of: has_primary_input_or_output CHEBI:29985 +relationship: has_primary_input_or_output CHEBI:29985 +created_by: pr +creation_date: 2011-05-24T04:30:38Z + [Term] id: GO:0097060 name: synaptic membrane @@ -123823,8 +109681,8 @@ namespace: molecular_function def: "Binding to an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure." [GOC:sjw, PMID:7583672] is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:33832 ! organic cyclic compound -relationship: has_input CHEBI:33832 ! organic cyclic compound +intersection_of: has_input CHEBI:33832 +relationship: has_input CHEBI:33832 created_by: pr creation_date: 2011-09-23T02:31:01Z @@ -123837,8 +109695,8 @@ synonym: "ammonium ion metabolism" EXACT [] synonym: "ammonium metabolic process" RELATED [] is_a: GO:0006807 ! nitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:28938 ! ammonium -relationship: has_primary_input_or_output CHEBI:28938 ! ammonium +intersection_of: has_primary_input_or_output CHEBI:28938 +relationship: has_primary_input_or_output CHEBI:28938 created_by: pr creation_date: 2011-09-28T04:21:30Z @@ -123960,10 +109818,10 @@ name: ammonium homeostasis namespace: biological_process def: "Any biological process involved in the maintenance of an internal steady state of ammonium." [GOC:yaf, PMID:12695560] synonym: "ammonia homeostasis" EXACT [] -is_a: GO:0098771 ! inorganic ion homeostasis +is_a: GO:0048878 ! chemical homeostasis intersection_of: GO:0048878 ! chemical homeostasis -intersection_of: regulates_levels_of CHEBI:28938 ! ammonium -relationship: regulates_levels_of CHEBI:28938 ! ammonium +intersection_of: regulates_levels_of CHEBI:28938 +relationship: regulates_levels_of CHEBI:28938 created_by: pr creation_date: 2012-03-22T02:51:22Z @@ -123977,7 +109835,7 @@ synonym: "cellular ammonium homeostasis" EXACT [] is_a: GO:0055082 ! intracellular chemical homeostasis is_a: GO:0097272 ! ammonium homeostasis intersection_of: GO:0055082 ! intracellular chemical homeostasis -intersection_of: regulates_levels_of CHEBI:28938 ! ammonium +intersection_of: regulates_levels_of CHEBI:28938 created_by: pr creation_date: 2012-03-22T02:54:38Z @@ -124008,34 +109866,6 @@ relationship: occurs_in CL:0000182 ! hepatocyte created_by: pr creation_date: 2012-03-29T10:23:21Z -[Term] -id: GO:0097305 -name: response to alcohol -namespace: biological_process -alt_id: GO:1990335 -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus." [GOC:pr, PMID:24014527] -synonym: "process resulting in tolerance to alcohol" NARROW [] -is_a: GO:0010033 ! response to organic substance -is_a: GO:1901700 ! response to oxygen-containing compound -intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:30879 ! alcohol -relationship: has_input CHEBI:30879 ! alcohol -created_by: pr -creation_date: 2012-05-15T03:48:45Z - -[Term] -id: GO:0097306 -name: cellular response to alcohol -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus." [GOC:pr] -is_a: GO:0071310 ! cellular response to organic substance -is_a: GO:0097305 ! response to alcohol -is_a: GO:1901701 ! cellular response to oxygen-containing compound -intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:30879 ! alcohol -created_by: pr -creation_date: 2012-05-15T03:49:51Z - [Term] id: GO:0097324 name: melanocyte migration @@ -124082,8 +109912,8 @@ subset: goslim_agr subset: goslim_mouse is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:63299 ! carbohydrate derivative -relationship: has_input CHEBI:63299 ! carbohydrate derivative +intersection_of: has_input CHEBI:63299 +relationship: has_input CHEBI:63299 created_by: pr creation_date: 2012-08-02T13:03:39Z @@ -124830,9 +110660,9 @@ def: "The process in which a monoatomic cation is transported across a membrane. synonym: "ATP hydrolysis coupled cation transmembrane transport" NARROW [] synonym: "cation transmembrane transport" BROAD [] is_a: GO:0006812 ! monoatomic cation transport -is_a: GO:0034220 ! monoatomic ion transmembrane transport +is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation +intersection_of: has_primary_input CHEBI:23906 intersection_of: results_in_transport_across GO:0016020 ! membrane [Term] @@ -124843,59 +110673,13 @@ def: "The directed movement of some substance from outside of a cell into a cell synonym: "uptake" BROAD [] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:24431 ! chemical entity +intersection_of: has_primary_input CHEBI:24431 intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure intersection_of: has_target_start_location GO:0005576 ! extracellular region -relationship: has_primary_input CHEBI:24431 ! chemical entity +relationship: has_primary_input CHEBI:24431 relationship: has_target_end_location GO:0005622 ! intracellular anatomical structure relationship: has_target_start_location GO:0005576 ! extracellular region -[Term] -id: GO:0098660 -name: inorganic ion transmembrane transport -namespace: biological_process -def: "The process in which an inorganic ion is transported across a membrane." [GOC:mah] -comment: Note that this term is not intended for use in annotating lateral movement within membranes. -synonym: "inorganic ion membrane transport" EXACT [] -synonym: "transmembrane inorganic ion transport" EXACT [GOC:dph, GOC:tb] -is_a: GO:0055085 ! transmembrane transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:36914 ! inorganic ion -intersection_of: results_in_transport_across GO:0016020 ! membrane -relationship: has_primary_input CHEBI:36914 ! inorganic ion - -[Term] -id: GO:0098661 -name: inorganic anion transmembrane transport -namespace: biological_process -def: "The process in which an inorganic anion is transported across a membrane." [GOC:mah] -comment: Note that this term is not intended for use in annotating lateral movement within membranes. -synonym: "inorganic anion membrane transport" EXACT [] -synonym: "transmembrane inorganic anion transport" EXACT [GOC:dph, GOC:tb] -is_a: GO:0015698 ! inorganic anion transport -is_a: GO:0098660 ! inorganic ion transmembrane transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:24834 ! inorganic anion -intersection_of: results_in_transport_across GO:0016020 ! membrane - -[Term] -id: GO:0098662 -name: inorganic cation transmembrane transport -namespace: biological_process -alt_id: GO:0015672 -alt_id: GO:0072511 -def: "A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah] -comment: Note that this term is not intended for use in annotating lateral movement within membranes. -synonym: "divalent inorganic cation transport" NARROW [] -synonym: "inorganic cation membrane transport" EXACT [] -synonym: "monovalent inorganic cation transport" NARROW [] -synonym: "transmembrane inorganic cation transport" EXACT [GOC:dph, GOC:tb] -is_a: GO:0098660 ! inorganic ion transmembrane transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:36915 ! inorganic cation -intersection_of: results_in_transport_across GO:0016020 ! membrane -relationship: has_primary_input CHEBI:36915 ! inorganic cation - [Term] id: GO:0098664 name: G protein-coupled serotonin receptor signaling pathway @@ -125063,17 +110847,6 @@ subset: prokaryote_subset is_a: GO:0008150 ! biological_process relationship: part_of GO:0009636 ! response to toxic substance -[Term] -id: GO:0098771 -name: inorganic ion homeostasis -namespace: biological_process -def: "Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell." [GOC:dos] -is_a: GO:0048878 ! chemical homeostasis -intersection_of: GO:0042592 ! homeostatic process -intersection_of: regulates_levels_of CHEBI:36914 ! inorganic ion -relationship: regulates_levels_of CHEBI:36914 ! inorganic ion -property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24455" xsd:anyURI - [Term] id: GO:0098772 name: molecular function regulator activity @@ -125506,7 +111279,7 @@ is_a: GO:0099541 ! trans-synaptic signaling by lipid intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: has_end_location GO:0098793 ! presynapse intersection_of: has_start_location GO:0098794 ! postsynapse -intersection_of: process_has_causal_agent CHEBI:18059 ! lipid +intersection_of: process_has_causal_agent CHEBI:18059 [Term] id: GO:0098923 @@ -125531,7 +111304,7 @@ is_a: GO:0099548 ! trans-synaptic signaling by nitric oxide intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: has_end_location GO:0098793 ! presynapse intersection_of: has_start_location GO:0098794 ! postsynapse -intersection_of: process_has_causal_agent CHEBI:16480 ! nitric oxide +intersection_of: process_has_causal_agent CHEBI:16480 [Term] id: GO:0098925 @@ -125545,7 +111318,7 @@ is_a: GO:0099555 ! trans-synaptic signaling by nitric oxide, modulating synaptic intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: has_end_location GO:0098793 ! presynapse intersection_of: has_start_location GO:0098794 ! postsynapse -intersection_of: process_has_causal_agent CHEBI:16480 ! nitric oxide +intersection_of: process_has_causal_agent CHEBI:16480 intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] @@ -125640,7 +111413,7 @@ is_a: GO:0099548 ! trans-synaptic signaling by nitric oxide intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: has_end_location GO:0098794 ! postsynapse intersection_of: has_start_location GO:0098793 ! presynapse -intersection_of: process_has_causal_agent CHEBI:16480 ! nitric oxide +intersection_of: process_has_causal_agent CHEBI:16480 [Term] id: GO:0098960 @@ -125800,7 +111573,7 @@ synonym: "G-protein coupled glutamate receptor activity" EXACT [] is_a: GO:0004930 ! G protein-coupled receptor activity is_a: GO:0008066 ! glutamate receptor activity intersection_of: GO:0004930 ! G protein-coupled receptor activity -intersection_of: has_input CHEBI:14321 ! glutamate(1-) +intersection_of: has_input CHEBI:14321 [Term] id: GO:0099003 @@ -125879,7 +111652,7 @@ is_a: GO:0099540 ! trans-synaptic signaling by neuropeptide intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: has_end_location GO:0098793 ! presynapse intersection_of: has_start_location GO:0098794 ! postsynapse -intersection_of: process_has_causal_agent CHEBI:16670 ! peptide +intersection_of: process_has_causal_agent CHEBI:16670 [Term] id: GO:0099083 @@ -125893,7 +111666,7 @@ is_a: GO:0099551 ! trans-synaptic signaling by neuropeptide, modulating synaptic intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: has_end_location GO:0098793 ! presynapse intersection_of: has_start_location GO:0098794 ! postsynapse -intersection_of: process_has_causal_agent CHEBI:16670 ! peptide +intersection_of: process_has_causal_agent CHEBI:16670 intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] @@ -125903,9 +111676,9 @@ namespace: molecular_function def: "Enables the transmembrane transfer of an inorganic cation by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] synonym: "ligand-gated cation channel activity" BROAD [] is_a: GO:0005261 ! monoatomic cation channel activity -is_a: GO:0015276 ! ligand-gated monoatomic ion channel activity +is_a: GO:0022834 ! ligand-gated channel activity intersection_of: GO:0022834 ! ligand-gated channel activity -intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation +intersection_of: has_primary_input CHEBI:23906 [Term] id: GO:0099096 @@ -125989,7 +111762,7 @@ is_a: GO:0006886 ! intracellular protein transport is_a: GO:0099118 ! microtubule-based protein transport intersection_of: GO:0046907 ! intracellular transport intersection_of: has_part GO:0046785 ! microtubule polymerization -intersection_of: has_primary_input CHEBI:36080 ! protein +intersection_of: has_primary_input CHEBI:36080 intersection_of: process_has_causal_agent GO:0005874 ! microtubule relationship: has_part GO:0046785 ! microtubule polymerization @@ -126124,8 +111897,8 @@ def: "Cell-cell signaling to or from a synapse, mediated by nitric oxide." [GOC: subset: goslim_synapse is_a: GO:0099536 ! synaptic signaling intersection_of: GO:0099536 ! synaptic signaling -intersection_of: process_has_causal_agent CHEBI:16480 ! nitric oxide -relationship: process_has_causal_agent CHEBI:16480 ! nitric oxide +intersection_of: process_has_causal_agent CHEBI:16480 +relationship: process_has_causal_agent CHEBI:16480 [Term] id: GO:0099170 @@ -126448,8 +112221,8 @@ def: "Cell-cell signaling to or from a synapse, mediated by a peptide." [GOC:dos subset: goslim_synapse is_a: GO:0099536 ! synaptic signaling intersection_of: GO:0099536 ! synaptic signaling -intersection_of: process_has_causal_agent CHEBI:16670 ! peptide -relationship: process_has_causal_agent CHEBI:16670 ! peptide +intersection_of: process_has_causal_agent CHEBI:16670 +relationship: process_has_causal_agent CHEBI:16670 [Term] id: GO:0099540 @@ -126460,7 +112233,7 @@ subset: goslim_synapse is_a: GO:0099537 ! trans-synaptic signaling is_a: GO:0099538 ! synaptic signaling via neuropeptide intersection_of: GO:0099537 ! trans-synaptic signaling -intersection_of: process_has_causal_agent CHEBI:16670 ! peptide +intersection_of: process_has_causal_agent CHEBI:16670 [Term] id: GO:0099541 @@ -126470,8 +112243,8 @@ def: "Cell-cell signaling from post to pre-synapse, across the synaptic cleft, m subset: goslim_synapse is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling -intersection_of: process_has_causal_agent CHEBI:18059 ! lipid -relationship: process_has_causal_agent CHEBI:18059 ! lipid +intersection_of: process_has_causal_agent CHEBI:18059 +relationship: process_has_causal_agent CHEBI:18059 [Term] id: GO:0099543 @@ -126490,7 +112263,7 @@ comment: Note that this term was created for the SynGO project, and will be obso subset: goslim_synapse is_a: GO:0140246 ! protein catabolic process at synapse intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:36080 ! protein +intersection_of: has_primary_input CHEBI:36080 intersection_of: occurs_in GO:0045202 ! synapse intersection_of: regulates GO:0007268 ! chemical synaptic transmission relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa @@ -126520,7 +112293,7 @@ subset: goslim_synapse is_a: GO:0099163 ! synaptic signaling by nitric oxide is_a: GO:0099543 ! trans-synaptic signaling by soluble gas intersection_of: GO:0099537 ! trans-synaptic signaling -intersection_of: process_has_causal_agent CHEBI:16480 ! nitric oxide +intersection_of: process_has_causal_agent CHEBI:16480 [Term] id: GO:0099550 @@ -126529,10 +112302,10 @@ namespace: biological_process def: "Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse +is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: regulates GO:0007268 ! chemical synaptic transmission -relationship: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099551 @@ -126544,7 +112317,7 @@ subset: goslim_synapse is_a: GO:0099540 ! trans-synaptic signaling by neuropeptide is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission intersection_of: GO:0099537 ! trans-synaptic signaling -intersection_of: process_has_causal_agent CHEBI:16670 ! peptide +intersection_of: process_has_causal_agent CHEBI:16670 intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] @@ -126557,7 +112330,7 @@ subset: goslim_synapse is_a: GO:0099541 ! trans-synaptic signaling by lipid is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission intersection_of: GO:0099537 ! trans-synaptic signaling -intersection_of: process_has_causal_agent CHEBI:18059 ! lipid +intersection_of: process_has_causal_agent CHEBI:18059 intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] @@ -126580,7 +112353,7 @@ subset: goslim_synapse is_a: GO:0099548 ! trans-synaptic signaling by nitric oxide is_a: GO:0099554 ! trans-synaptic signaling by soluble gas, modulating synaptic transmission intersection_of: GO:0099537 ! trans-synaptic signaling -intersection_of: process_has_causal_agent CHEBI:16480 ! nitric oxide +intersection_of: process_has_causal_agent CHEBI:16480 intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] @@ -126641,7 +112414,7 @@ subset: goslim_synapse is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0140250 ! regulation protein catabolic process at synapse intersection_of: GO:0065007 ! biological regulation -intersection_of: has_input CHEBI:36080 ! protein +intersection_of: has_input CHEBI:36080 intersection_of: occurs_in GO:0045202 ! synapse intersection_of: regulates GO:0007268 ! chemical synaptic transmission intersection_of: regulates GO:0009056 ! catabolic process @@ -126723,8 +112496,8 @@ namespace: molecular_function def: "Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates." [GOC:dos] is_a: GO:0004888 ! transmembrane signaling receptor activity intersection_of: GO:0004888 ! transmembrane signaling receptor activity -intersection_of: has_input CHEBI:350546 ! serotonin(1+) -relationship: has_input CHEBI:350546 ! serotonin(1+) +intersection_of: has_input CHEBI:350546 +relationship: has_input CHEBI:350546 [Term] id: GO:0099601 @@ -126753,9 +112526,9 @@ name: ligand-gated calcium channel activity namespace: molecular_function def: "Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts." [GOC:dos] is_a: GO:0005262 ! calcium channel activity -is_a: GO:0099094 ! ligand-gated monoatomic cation channel activity +is_a: GO:0022834 ! ligand-gated channel activity intersection_of: GO:0022834 ! ligand-gated channel activity -intersection_of: has_primary_input CHEBI:29108 ! calcium(2+) +intersection_of: has_primary_input CHEBI:29108 relationship: part_of GO:0019722 ! calcium-mediated signaling [Term] @@ -127347,8 +113120,8 @@ namespace: biological_process def: "Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." [GOC:vw, PMID:25656103] is_a: GO:1990748 ! cellular detoxification intersection_of: GO:1990748 ! cellular detoxification -intersection_of: has_input CHEBI:17478 ! aldehyde -relationship: has_input CHEBI:17478 ! aldehyde +intersection_of: has_primary_input CHEBI:17478 +relationship: has_primary_input CHEBI:17478 relationship: part_of GO:0110096 ! cellular response to aldehyde created_by: kmv creation_date: 2018-02-16T21:19:20Z @@ -127358,11 +113131,10 @@ id: GO:0110096 name: cellular response to aldehyde namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus." [GOC:vw, PMID:25656103] -is_a: GO:0010033 ! response to organic substance -is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:17478 ! aldehyde -relationship: has_input CHEBI:17478 ! aldehyde +intersection_of: has_input CHEBI:17478 +relationship: has_input CHEBI:17478 created_by: kmv creation_date: 2018-02-16T21:29:18Z @@ -127579,10 +113351,10 @@ id: GO:0120023 name: somatostatin binding namespace: molecular_function def: "Binding to somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatostatin." [GOC:cvs, PMID:20472043] -is_a: GO:0017046 ! peptide hormone binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:64628 ! somatostatin -relationship: has_input CHEBI:64628 ! somatostatin +intersection_of: has_input CHEBI:64628 +relationship: has_input CHEBI:64628 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13143" xsd:anyURI created_by: krc creation_date: 2017-03-17T14:54:21Z @@ -127717,8 +113489,8 @@ namespace: biological_process def: "The formation of mature glucagon by proteolysis of the precursor proglucagon." [PMID:28719828] is_a: GO:0016486 ! peptide hormone processing intersection_of: GO:0016485 ! protein processing -intersection_of: has_primary_input_or_output CHEBI:5391 ! glucagon -relationship: has_primary_input_or_output CHEBI:5391 ! glucagon +intersection_of: has_primary_input_or_output CHEBI:5391 +relationship: has_primary_input_or_output CHEBI:5391 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14505" xsd:anyURI created_by: krc creation_date: 2017-11-08T19:31:42Z @@ -127752,8 +113524,8 @@ namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." [GOC:krc, GOC:nln] is_a: GO:0006694 ! steroid biosynthetic process intersection_of: GO:0006694 ! steroid biosynthetic process -intersection_of: has_output CHEBI:26764 ! steroid hormone -relationship: has_output CHEBI:26764 ! steroid hormone +intersection_of: has_output CHEBI:26764 +relationship: has_output CHEBI:26764 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16000" xsd:anyURI created_by: krc creation_date: 2019-05-20T22:34:00Z @@ -127916,107 +113688,6 @@ property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/ created_by: krc creation_date: 2020-06-05T23:43:04Z -[Term] -id: GO:0120251 -name: hydrocarbon biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of a hydrocarbon, a compound consisting of carbon and hydrogen only." [GOC:krc, Wikipedia:Hydrocarbon] -synonym: "hydrocarbon anabolism" EXACT [GOC:krc] -synonym: "hydrocarbon biosynthesis" EXACT [GOC:krc] -synonym: "hydrocarbon formation" EXACT [GOC:krc] -synonym: "hydrocarbon synthesis" EXACT [GOC:krc] -is_a: GO:0120252 ! hydrocarbon metabolic process -is_a: GO:1901576 ! organic substance biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:24632 ! hydrocarbon -relationship: has_primary_output CHEBI:24632 ! hydrocarbon -property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19842" xsd:anyURI -created_by: krc -creation_date: 2020-09-02T20:35:53Z - -[Term] -id: GO:0120252 -name: hydrocarbon metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only." [GOC:krc, Wikipedia:Hydrocarbon] -synonym: "hydrocarbon metabolism" EXACT [GOC:krc] -is_a: GO:0071704 ! organic substance metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:24632 ! hydrocarbon -relationship: has_primary_input_or_output CHEBI:24632 ! hydrocarbon -property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19842" xsd:anyURI -created_by: krc -creation_date: 2020-09-02T20:47:28Z - -[Term] -id: GO:0120253 -name: hydrocarbon catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of a hydrocarbon, a compound consisting of carbon and hydrogen only." [GOC:krc, Wikipedia:Hydrocarbon] -synonym: "hydrocarbon breakdown" EXACT [GOC:krc] -synonym: "hydrocarbon catabolism" EXACT [GOC:krc] -synonym: "hydrocarbon degradation" EXACT [GOC:krc] -is_a: GO:0120252 ! hydrocarbon metabolic process -is_a: GO:1901575 ! organic substance catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:24632 ! hydrocarbon -relationship: has_primary_input CHEBI:24632 ! hydrocarbon -property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19842" xsd:anyURI -created_by: krc -creation_date: 2020-09-02T20:58:57Z - -[Term] -id: GO:0120254 -name: olefinic compound metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C)." [GOC:krc] -synonym: "alkene substituted compound metabolic process" EXACT [] -synonym: "alkene substituted compound metabolism" EXACT [] -is_a: GO:0071704 ! organic substance metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:78840 ! olefinic compound -relationship: has_primary_input_or_output CHEBI:78840 ! olefinic compound -property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19936" xsd:anyURI -created_by: krc -creation_date: 2020-09-02T23:13:44Z - -[Term] -id: GO:0120255 -name: olefinic compound biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C)." [GOC:krc] -synonym: "alkene substituted compound anabolic process" EXACT [GOC:krc] -synonym: "alkene substituted compound anabolism" EXACT [GOC:krc] -synonym: "alkene substituted compound biosynthesis" EXACT [GOC:krc] -synonym: "alkene substituted compound biosynthetic process" EXACT [GOC:krc] -synonym: "alkene substituted compound synthesis" EXACT [GOC:krc] -is_a: GO:0120254 ! olefinic compound metabolic process -is_a: GO:1901576 ! organic substance biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:78840 ! olefinic compound -relationship: has_primary_output CHEBI:78840 ! olefinic compound -property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19936" xsd:anyURI -created_by: krc -creation_date: 2020-09-02T23:30:20Z - -[Term] -id: GO:0120256 -name: olefinic compound catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C)." [GOC:krc] -synonym: "alkene substituted compound breakdown" EXACT [GOC:krc] -synonym: "alkene substituted compound catabolic process" EXACT [GOC:krc] -synonym: "alkene substituted compound catabolism" EXACT [GOC:krc] -synonym: "alkene substituted compound degradation" EXACT [GOC:krc] -is_a: GO:0120254 ! olefinic compound metabolic process -is_a: GO:1901575 ! organic substance catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:78840 ! olefinic compound -relationship: has_primary_input CHEBI:78840 ! olefinic compound -property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19936" xsd:anyURI -created_by: krc -creation_date: 2020-09-02T23:30:41Z - [Term] id: GO:0120275 name: cerebral blood circulation @@ -128201,7 +113872,7 @@ id: GO:0140075 name: regulation of lipoprotein transport namespace: biological_process def: "Any process that controls lipoprotein transport." [GOC:BHF, GOC:BHF_miRNA, GOC:RPH, PMID:26501192] -is_a: GO:0051223 ! regulation of protein transport +is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042953 ! lipoprotein transport relationship: regulates GO:0042953 ! lipoprotein transport @@ -128213,7 +113884,7 @@ id: GO:0140076 name: negative regulation of lipoprotein transport namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lipoprotein transport." [GOC:BHF, GOC:BHF_miRNA, GOC:RPH, PMID:26501192] -is_a: GO:0051224 ! negative regulation of protein transport +is_a: GO:0051051 ! negative regulation of transport is_a: GO:0140075 ! regulation of lipoprotein transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042953 ! lipoprotein transport @@ -128226,7 +113897,7 @@ id: GO:0140077 name: positive regulation of lipoprotein transport namespace: biological_process def: "Any process that activates or increases the rate or extent of lipoprotein transport." [GOC:BHF, GOC:BHF_miRNA, GOC:RPH, PMID:26501192] -is_a: GO:0051222 ! positive regulation of protein transport +is_a: GO:0051050 ! positive regulation of transport is_a: GO:0140075 ! regulation of lipoprotein transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042953 ! lipoprotein transport @@ -128256,10 +113927,10 @@ namespace: molecular_function def: "Catalytic activity that acts to modify DNA." [GOC:molecular_function_refactoring, GOC:pdt] subset: goslim_generic subset: prokaryote_subset -is_a: GO:0140640 ! catalytic activity, acting on a nucleic acid +is_a: GO:0003824 ! catalytic activity intersection_of: GO:0003824 ! catalytic activity -intersection_of: has_input CHEBI:16991 ! deoxyribonucleic acid -relationship: has_input CHEBI:16991 ! deoxyribonucleic acid +intersection_of: has_input CHEBI:16991 +relationship: has_input CHEBI:16991 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI created_by: pg creation_date: 2017-09-14T12:03:51Z @@ -128271,10 +113942,10 @@ namespace: molecular_function def: "Catalytic activity that acts to modify RNA, driven by ATP hydrolysis." [GOC:molecular_function_refactoring, GOC:pdt] subset: goslim_generic subset: prokaryote_subset -is_a: GO:0140640 ! catalytic activity, acting on a nucleic acid +is_a: GO:0003824 ! catalytic activity intersection_of: GO:0003824 ! catalytic activity -intersection_of: has_input CHEBI:33697 ! ribonucleic acid -relationship: has_input CHEBI:33697 ! ribonucleic acid +intersection_of: has_input CHEBI:33697 +relationship: has_input CHEBI:33697 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21612" xsd:anyURI created_by: pg @@ -128285,10 +113956,10 @@ id: GO:0140103 name: catalytic activity, acting on a glycoprotein namespace: molecular_function def: "Catalysis of a biochemical reaction at physiological temperatures in which one of the substrates is a glycoprotein." [GOC:molecular_function_refactoring, GOC:pdt] -is_a: GO:0140096 ! catalytic activity, acting on a protein +is_a: GO:0003824 ! catalytic activity intersection_of: GO:0003824 ! catalytic activity -intersection_of: has_input CHEBI:17089 ! glycoprotein -relationship: has_input CHEBI:17089 ! glycoprotein +intersection_of: has_input CHEBI:17089 +relationship: has_input CHEBI:17089 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI created_by: pg creation_date: 2017-09-15T19:27:54Z @@ -128510,7 +114181,7 @@ comment: Note that this term was created for the SynGO project, and will be obso subset: goslim_synapse is_a: GO:0030163 ! protein catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:36080 ! protein +intersection_of: has_primary_input CHEBI:36080 intersection_of: occurs_in GO:0045202 ! synapse relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in GO:0045202 ! synapse @@ -128528,7 +114199,7 @@ comment: Note that this term was created for the SynGO project, and will be obso subset: goslim_synapse is_a: GO:0140246 ! protein catabolic process at synapse intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:36080 ! protein +intersection_of: has_primary_input CHEBI:36080 intersection_of: occurs_in GO:0098793 ! presynapse relationship: occurs_in GO:0098793 ! presynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI @@ -128544,7 +114215,7 @@ comment: Note that this term was created for the SynGO project, and will be obso subset: goslim_synapse is_a: GO:0140246 ! protein catabolic process at synapse intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:36080 ! protein +intersection_of: has_primary_input CHEBI:36080 intersection_of: occurs_in GO:0098794 ! postsynapse relationship: occurs_in GO:0098794 ! postsynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI @@ -128560,10 +114231,10 @@ comment: Note that this term was created for the SynGO project, and will be obso subset: goslim_synapse is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation -intersection_of: has_input CHEBI:36080 ! protein +intersection_of: has_input CHEBI:36080 intersection_of: occurs_in GO:0045202 ! synapse intersection_of: regulates GO:0009056 ! catabolic process -relationship: has_input CHEBI:36080 ! protein +relationship: has_input CHEBI:36080 relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in GO:0045202 ! synapse relationship: only_in_taxon NCBITaxon:33208 ! Metazoa @@ -128580,7 +114251,7 @@ comment: Note that this term was created for the SynGO project, and will be obso subset: goslim_synapse is_a: GO:0140250 ! regulation protein catabolic process at synapse intersection_of: GO:0065007 ! biological regulation -intersection_of: has_input CHEBI:36080 ! protein +intersection_of: has_input CHEBI:36080 intersection_of: occurs_in GO:0098793 ! presynapse intersection_of: regulates GO:0009056 ! catabolic process relationship: occurs_in GO:0098793 ! presynapse @@ -128597,7 +114268,7 @@ comment: Note that this term was created for the SynGO project, and will be obso subset: goslim_synapse is_a: GO:0140250 ! regulation protein catabolic process at synapse intersection_of: GO:0065007 ! biological regulation -intersection_of: has_input CHEBI:36080 ! protein +intersection_of: has_input CHEBI:36080 intersection_of: occurs_in GO:0098794 ! postsynapse intersection_of: regulates GO:0009056 ! catabolic process relationship: occurs_in GO:0098794 ! postsynapse @@ -128677,7 +114348,7 @@ synonym: "lipid efflux" BROAD [] is_a: GO:0006869 ! lipid transport is_a: GO:0140352 ! export from cell intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:18059 ! lipid +intersection_of: has_primary_input CHEBI:18059 intersection_of: has_target_end_location GO:0005576 ! extracellular region intersection_of: has_target_start_location GO:0005622 ! intracellular anatomical structure created_by: pg @@ -128690,11 +114361,12 @@ namespace: biological_process def: "The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." [GOC:pg] synonym: "lipid uptake" BROAD [] is_a: GO:0006869 ! lipid transport -is_a: GO:0098657 ! import into cell intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:18059 ! lipid +intersection_of: has_primary_input CHEBI:18059 intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure intersection_of: has_target_start_location GO:0005576 ! extracellular region +relationship: has_target_end_location GO:0005622 ! intracellular anatomical structure +relationship: has_target_start_location GO:0005576 ! extracellular region created_by: pg creation_date: 2019-05-22T11:38:15Z @@ -128754,8 +114426,8 @@ namespace: molecular_function def: "Catalytic activity that acts to modify a nucleic acid." [GOC:pg] is_a: GO:0003824 ! catalytic activity intersection_of: GO:0003824 ! catalytic activity -intersection_of: has_input CHEBI:33696 ! nucleic acid -relationship: has_input CHEBI:33696 ! nucleic acid +intersection_of: has_input CHEBI:33696 +relationship: has_input CHEBI:33696 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21402" xsd:anyURI created_by: pg creation_date: 2021-05-11T06:31:07Z @@ -128903,26 +114575,12 @@ def: "The elimination of ammonium ions from an excretory cell." [PMID:25740900] synonym: "ammonia excretion" RELATED [] is_a: GO:0007588 ! excretion intersection_of: GO:0007588 ! excretion -intersection_of: has_primary_input CHEBI:28938 ! ammonium -relationship: has_primary_input CHEBI:28938 ! ammonium +intersection_of: has_primary_input CHEBI:28938 +relationship: has_primary_input CHEBI:28938 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22368" xsd:anyURI created_by: pg creation_date: 2021-11-24T17:55:51Z -[Term] -id: GO:0140961 -name: cellular detoxification of metal ion -namespace: biological_process -def: "Any process carried out at the cellular level that reduces or removes the toxicity of a metal ion." [PMID:26729300, PMID:33046888, PMID:34442707] -synonym: "cellular detoxification of metal cation" EXACT [] -is_a: GO:0061687 ! detoxification of inorganic compound -is_a: GO:1990748 ! cellular detoxification -intersection_of: GO:1990748 ! cellular detoxification -intersection_of: has_primary_input CHEBI:25213 ! metal cation -relationship: has_primary_input CHEBI:25213 ! metal cation -created_by: pg -creation_date: 2022-12-07T15:35:18Z - [Term] id: GO:0140962 name: multicellular organismal-level chemical homeostasis @@ -128933,7 +114591,7 @@ synonym: "organismal level chemical homeostasis" EXACT [] is_a: GO:0048871 ! multicellular organismal-level homeostasis is_a: GO:0048878 ! chemical homeostasis intersection_of: GO:0048871 ! multicellular organismal-level homeostasis -intersection_of: regulates_levels_of CHEBI:24431 ! chemical entity +intersection_of: regulates_levels_of CHEBI:24431 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24554" xsd:anyURI created_by: pg creation_date: 2022-12-12T09:11:06Z @@ -129342,7 +115000,7 @@ def: "The regulated release of catecholamine by a cell in which the catecholamin is_a: GO:0007269 ! neurotransmitter secretion is_a: GO:0050432 ! catecholamine secretion intersection_of: GO:0007269 ! neurotransmitter secretion -intersection_of: has_primary_input CHEBI:33567 ! catecholamine +intersection_of: has_primary_input CHEBI:33567 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23804" xsd:anyURI created_by: rynl creation_date: 2022-08-17T00:36:44Z @@ -129762,7 +115420,6 @@ synonym: "regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process -is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030213 ! hyaluronan biosynthetic process relationship: regulates GO:0030213 ! hyaluronan biosynthetic process @@ -129798,9 +115455,8 @@ synonym: "negative regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] -is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process +is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process -is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process is_a: GO:1900125 ! regulation of hyaluronan biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030213 ! hyaluronan biosynthetic process @@ -129837,9 +115493,8 @@ synonym: "upregulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan synthesis" EXACT [GOC:TermGenie] -is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process -is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process is_a: GO:1900125 ! regulation of hyaluronan biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030213 ! hyaluronan biosynthetic process @@ -130757,124 +116412,6 @@ relationship: positively_regulates GO:0002213 ! defense response to insect created_by: dhl creation_date: 2012-04-12T04:44:10Z -[Term] -id: GO:1900376 -name: regulation of secondary metabolite biosynthetic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] -synonym: "regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] -is_a: GO:0009889 ! regulation of biosynthetic process -is_a: GO:0043455 ! regulation of secondary metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0044550 ! secondary metabolite biosynthetic process -relationship: regulates GO:0044550 ! secondary metabolite biosynthetic process -created_by: di -creation_date: 2012-04-17T01:55:23Z - -[Term] -id: GO:1900377 -name: negative regulation of secondary metabolite biosynthetic process -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] -synonym: "down regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] -synonym: "down regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] -synonym: "down-regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] -synonym: "down-regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] -synonym: "downregulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] -synonym: "downregulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] -synonym: "inhibition of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] -synonym: "inhibition of secondary metabolite biosynthetic process" NARROW [GOC:TermGenie] -synonym: "negative regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] -is_a: GO:0009890 ! negative regulation of biosynthetic process -is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0044550 ! secondary metabolite biosynthetic process -relationship: negatively_regulates GO:0044550 ! secondary metabolite biosynthetic process -created_by: di -creation_date: 2012-04-17T01:55:32Z - -[Term] -id: GO:1900378 -name: positive regulation of secondary metabolite biosynthetic process -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] -synonym: "activation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] -synonym: "activation of secondary metabolite biosynthetic process" NARROW [GOC:TermGenie] -synonym: "positive regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] -synonym: "up regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] -synonym: "up regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] -synonym: "up-regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] -synonym: "up-regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] -synonym: "upregulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] -synonym: "upregulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] -is_a: GO:0009891 ! positive regulation of biosynthetic process -is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0044550 ! secondary metabolite biosynthetic process -relationship: positively_regulates GO:0044550 ! secondary metabolite biosynthetic process -created_by: di -creation_date: 2012-04-17T01:55:41Z - -[Term] -id: GO:1900407 -name: regulation of cellular response to oxidative stress -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of cellular response to oxidative stress." [GOC:mah, GOC:TermGenie] -synonym: "regulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] -is_a: GO:0080135 ! regulation of cellular response to stress -is_a: GO:1902882 ! regulation of response to oxidative stress -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0034599 ! cellular response to oxidative stress -relationship: regulates GO:0034599 ! cellular response to oxidative stress -created_by: mah -creation_date: 2012-04-20T03:30:52Z - -[Term] -id: GO:1900408 -name: negative regulation of cellular response to oxidative stress -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress." [GOC:mah, GOC:TermGenie] -synonym: "down regulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] -synonym: "down regulation of cellular response to oxidative stress" EXACT [GOC:TermGenie] -synonym: "down-regulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] -synonym: "down-regulation of cellular response to oxidative stress" EXACT [GOC:TermGenie] -synonym: "downregulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] -synonym: "downregulation of cellular response to oxidative stress" EXACT [GOC:TermGenie] -synonym: "inhibition of adaptive response to oxidative stress" NARROW [GOC:TermGenie] -synonym: "inhibition of cellular response to oxidative stress" NARROW [GOC:TermGenie] -synonym: "negative regulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] -is_a: GO:0048523 ! negative regulation of cellular process -is_a: GO:1900407 ! regulation of cellular response to oxidative stress -is_a: GO:1902883 ! negative regulation of response to oxidative stress -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0034599 ! cellular response to oxidative stress -relationship: negatively_regulates GO:0034599 ! cellular response to oxidative stress -created_by: mah -creation_date: 2012-04-20T03:31:05Z - -[Term] -id: GO:1900409 -name: positive regulation of cellular response to oxidative stress -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress." [GOC:mah, GOC:TermGenie] -synonym: "activation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] -synonym: "activation of cellular response to oxidative stress" NARROW [GOC:TermGenie] -synonym: "positive regulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] -synonym: "up regulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] -synonym: "up regulation of cellular response to oxidative stress" EXACT [GOC:TermGenie] -synonym: "up-regulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] -synonym: "up-regulation of cellular response to oxidative stress" EXACT [GOC:TermGenie] -synonym: "upregulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] -synonym: "upregulation of cellular response to oxidative stress" EXACT [GOC:TermGenie] -is_a: GO:0048522 ! positive regulation of cellular process -is_a: GO:1900407 ! regulation of cellular response to oxidative stress -is_a: GO:1902884 ! positive regulation of response to oxidative stress -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0034599 ! cellular response to oxidative stress -relationship: positively_regulates GO:0034599 ! cellular response to oxidative stress -created_by: mah -creation_date: 2012-04-20T03:31:16Z - [Term] id: GO:1900424 name: regulation of defense response to bacterium @@ -131059,40 +116596,6 @@ relationship: positively_regulates GO:0007215 ! glutamate receptor signaling pat created_by: rl creation_date: 2012-04-27T03:46:03Z -[Term] -id: GO:1900619 -name: acetate ester metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid." [GOC:TermGenie] -synonym: "acetate ester metabolism" EXACT [GOC:TermGenie] -synonym: "acetyl ester metabolic process" EXACT [CHEBI:47622] -synonym: "acetyl ester metabolism" EXACT [CHEBI:47622] -is_a: GO:0071704 ! organic substance metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:47622 ! acetate ester -relationship: has_primary_input_or_output CHEBI:47622 ! acetate ester -created_by: bf -creation_date: 2012-05-16T12:29:51Z - -[Term] -id: GO:1900620 -name: acetate ester biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of an acetate esteran acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid." [GOC:TermGenie, PMID:15042596] -synonym: "acetate ester anabolism" EXACT [GOC:TermGenie] -synonym: "acetate ester biosynthesis" EXACT [GOC:TermGenie] -synonym: "acetate ester formation" EXACT [GOC:TermGenie] -synonym: "acetate ester synthesis" EXACT [GOC:TermGenie] -synonym: "acetyl ester biosynthesis" EXACT [CHEBI:47622] -synonym: "acetyl ester biosynthetic process" EXACT [CHEBI:47622] -is_a: GO:1900619 ! acetate ester metabolic process -is_a: GO:1901576 ! organic substance biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:47622 ! acetate ester -relationship: has_primary_output CHEBI:47622 ! acetate ester -created_by: bf -creation_date: 2012-05-16T12:30:12Z - [Term] id: GO:1900825 name: regulation of membrane depolarization during cardiac muscle cell action potential @@ -131139,29 +116642,12 @@ relationship: positively_regulates GO:0086012 ! membrane depolarization during c created_by: rl creation_date: 2012-06-06T04:15:48Z -[Term] -id: GO:1901003 -name: negative regulation of fermentation -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of fermentation." [GOC:TermGenie] -synonym: "down regulation of fermentation" EXACT [GOC:TermGenie] -synonym: "down-regulation of fermentation" EXACT [GOC:TermGenie] -synonym: "downregulation of fermentation" EXACT [GOC:TermGenie] -synonym: "inhibition of fermentation" NARROW [GOC:TermGenie] -is_a: GO:0031324 ! negative regulation of cellular metabolic process -is_a: GO:0043465 ! regulation of fermentation -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0006113 ! fermentation -relationship: negatively_regulates GO:0006113 ! fermentation -created_by: al -creation_date: 2012-06-15T08:21:31Z - [Term] id: GO:1901019 name: regulation of calcium ion transmembrane transporter activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity." [GOC:BHF, GOC:TermGenie] -is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity +is_a: GO:0022898 ! regulation of transmembrane transporter activity is_a: GO:1903169 ! regulation of calcium ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0015085 ! calcium ion transmembrane transporter activity @@ -131178,7 +116664,7 @@ synonym: "down regulation of calcium ion transmembrane transporter activity" EXA synonym: "down-regulation of calcium ion transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "downregulation of calcium ion transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "inhibition of calcium ion transmembrane transporter activity" NARROW [GOC:TermGenie] -is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity +is_a: GO:0032410 ! negative regulation of transporter activity is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity is_a: GO:1903170 ! negative regulation of calcium ion transmembrane transport intersection_of: GO:0065007 ! biological regulation @@ -131196,7 +116682,7 @@ synonym: "activation of calcium ion transmembrane transporter activity" NARROW [ synonym: "up regulation of calcium ion transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "up-regulation of calcium ion transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "upregulation of calcium ion transmembrane transporter activity" EXACT [GOC:TermGenie] -is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity +is_a: GO:0032411 ! positive regulation of transporter activity is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity is_a: GO:1904427 ! positive regulation of calcium ion transmembrane transport intersection_of: GO:0065007 ! biological regulation @@ -131205,131 +116691,6 @@ relationship: positively_regulates GO:0015085 ! calcium ion transmembrane transp created_by: rl creation_date: 2012-06-15T07:54:40Z -[Term] -id: GO:1901031 -name: regulation of response to reactive oxygen species -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of response to reactive oxygen species." [GOC:kmv, GOC:TermGenie] -synonym: "regulation of response to active oxygen species" EXACT [GOC:TermGenie] -synonym: "regulation of response to AOS" EXACT [GOC:TermGenie] -synonym: "regulation of response to reactive oxidative species" EXACT [GOC:TermGenie] -synonym: "regulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] -synonym: "regulation of response to ROI" EXACT [GOC:TermGenie] -synonym: "regulation of response to ROS" EXACT [GOC:TermGenie] -is_a: GO:1902882 ! regulation of response to oxidative stress -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0000302 ! response to reactive oxygen species -relationship: regulates GO:0000302 ! response to reactive oxygen species -created_by: kmv -creation_date: 2012-06-20T07:47:06Z - -[Term] -id: GO:1901032 -name: negative regulation of response to reactive oxygen species -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species." [GOC:kmv, GOC:TermGenie] -synonym: "down regulation of response to active oxygen species" EXACT [GOC:TermGenie] -synonym: "down regulation of response to AOS" EXACT [GOC:TermGenie] -synonym: "down regulation of response to reactive oxidative species" EXACT [GOC:TermGenie] -synonym: "down regulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] -synonym: "down regulation of response to reactive oxygen species" EXACT [GOC:TermGenie] -synonym: "down regulation of response to ROI" EXACT [GOC:TermGenie] -synonym: "down regulation of response to ROS" EXACT [GOC:TermGenie] -synonym: "down-regulation of response to active oxygen species" EXACT [GOC:TermGenie] -synonym: "down-regulation of response to AOS" EXACT [GOC:TermGenie] -synonym: "down-regulation of response to reactive oxidative species" EXACT [GOC:TermGenie] -synonym: "down-regulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] -synonym: "down-regulation of response to reactive oxygen species" EXACT [GOC:TermGenie] -synonym: "down-regulation of response to ROI" EXACT [GOC:TermGenie] -synonym: "down-regulation of response to ROS" EXACT [GOC:TermGenie] -synonym: "downregulation of response to active oxygen species" EXACT [GOC:TermGenie] -synonym: "downregulation of response to AOS" EXACT [GOC:TermGenie] -synonym: "downregulation of response to reactive oxidative species" EXACT [GOC:TermGenie] -synonym: "downregulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] -synonym: "downregulation of response to reactive oxygen species" EXACT [GOC:TermGenie] -synonym: "downregulation of response to ROI" EXACT [GOC:TermGenie] -synonym: "downregulation of response to ROS" EXACT [GOC:TermGenie] -synonym: "inhibition of response to active oxygen species" EXACT [GOC:TermGenie] -synonym: "inhibition of response to AOS" EXACT [GOC:TermGenie] -synonym: "inhibition of response to reactive oxidative species" EXACT [GOC:TermGenie] -synonym: "inhibition of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] -synonym: "inhibition of response to reactive oxygen species" NARROW [GOC:TermGenie] -synonym: "inhibition of response to ROI" EXACT [GOC:TermGenie] -synonym: "inhibition of response to ROS" EXACT [GOC:TermGenie] -synonym: "negative regulation of response to active oxygen species" EXACT [GOC:TermGenie] -synonym: "negative regulation of response to AOS" EXACT [GOC:TermGenie] -synonym: "negative regulation of response to reactive oxidative species" EXACT [GOC:TermGenie] -synonym: "negative regulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] -synonym: "negative regulation of response to ROI" EXACT [GOC:TermGenie] -synonym: "negative regulation of response to ROS" EXACT [GOC:TermGenie] -is_a: GO:1901031 ! regulation of response to reactive oxygen species -is_a: GO:1902883 ! negative regulation of response to oxidative stress -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0000302 ! response to reactive oxygen species -relationship: negatively_regulates GO:0000302 ! response to reactive oxygen species -created_by: kmv -creation_date: 2012-06-20T07:47:28Z - -[Term] -id: GO:1901033 -name: positive regulation of response to reactive oxygen species -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species." [GOC:kmv, GOC:TermGenie] -synonym: "activation of response to active oxygen species" EXACT [GOC:TermGenie] -synonym: "activation of response to AOS" EXACT [GOC:TermGenie] -synonym: "activation of response to reactive oxidative species" EXACT [GOC:TermGenie] -synonym: "activation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] -synonym: "activation of response to reactive oxygen species" NARROW [GOC:TermGenie] -synonym: "activation of response to ROI" EXACT [GOC:TermGenie] -synonym: "activation of response to ROS" EXACT [GOC:TermGenie] -synonym: "positive regulation of response to active oxygen species" EXACT [GOC:TermGenie] -synonym: "positive regulation of response to AOS" EXACT [GOC:TermGenie] -synonym: "positive regulation of response to reactive oxidative species" EXACT [GOC:TermGenie] -synonym: "positive regulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] -synonym: "positive regulation of response to ROI" EXACT [GOC:TermGenie] -synonym: "positive regulation of response to ROS" EXACT [GOC:TermGenie] -synonym: "up regulation of response to active oxygen species" EXACT [GOC:TermGenie] -synonym: "up regulation of response to AOS" EXACT [GOC:TermGenie] -synonym: "up regulation of response to reactive oxidative species" EXACT [GOC:TermGenie] -synonym: "up regulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] -synonym: "up regulation of response to reactive oxygen species" EXACT [GOC:TermGenie] -synonym: "up regulation of response to ROI" EXACT [GOC:TermGenie] -synonym: "up regulation of response to ROS" EXACT [GOC:TermGenie] -synonym: "up-regulation of response to active oxygen species" EXACT [GOC:TermGenie] -synonym: "up-regulation of response to AOS" EXACT [GOC:TermGenie] -synonym: "up-regulation of response to reactive oxidative species" EXACT [GOC:TermGenie] -synonym: "up-regulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] -synonym: "up-regulation of response to reactive oxygen species" EXACT [GOC:TermGenie] -synonym: "up-regulation of response to ROI" EXACT [GOC:TermGenie] -synonym: "up-regulation of response to ROS" EXACT [GOC:TermGenie] -synonym: "upregulation of response to active oxygen species" EXACT [GOC:TermGenie] -synonym: "upregulation of response to AOS" EXACT [GOC:TermGenie] -synonym: "upregulation of response to reactive oxidative species" EXACT [GOC:TermGenie] -synonym: "upregulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] -synonym: "upregulation of response to reactive oxygen species" EXACT [GOC:TermGenie] -synonym: "upregulation of response to ROI" EXACT [GOC:TermGenie] -synonym: "upregulation of response to ROS" EXACT [GOC:TermGenie] -is_a: GO:1901031 ! regulation of response to reactive oxygen species -is_a: GO:1902884 ! positive regulation of response to oxidative stress -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0000302 ! response to reactive oxygen species -relationship: positively_regulates GO:0000302 ! response to reactive oxygen species -created_by: kmv -creation_date: 2012-06-20T07:47:35Z - -[Term] -id: GO:1901089 -name: acetate ester metabolic process involved in fermentation -namespace: biological_process -def: "Any acetate ester metabolic process that is involved in fermentation." [GOC:sgd_curators, GOC:TermGenie] -synonym: "acetate ester metabolic process during fermentation" EXACT [GOC:sgd_curators] -is_a: GO:1900619 ! acetate ester metabolic process -intersection_of: GO:1900619 ! acetate ester metabolic process -intersection_of: part_of GO:0006113 ! fermentation -relationship: part_of GO:0006113 ! fermentation -created_by: rb -creation_date: 2012-07-05T11:47:17Z - [Term] id: GO:1901135 name: carbohydrate derivative metabolic process @@ -131340,10 +116701,10 @@ subset: goslim_generic subset: goslim_mouse subset: prokaryote_subset synonym: "carbohydrate derivative metabolism" EXACT [GOC:TermGenie] -is_a: GO:0071704 ! organic substance metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:63299 ! carbohydrate derivative -relationship: has_primary_input_or_output CHEBI:63299 ! carbohydrate derivative +intersection_of: has_primary_input_or_output CHEBI:63299 +relationship: has_primary_input_or_output CHEBI:63299 created_by: bf creation_date: 2012-07-12T04:05:09Z @@ -131355,11 +116716,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of carbohyd synonym: "carbohydrate derivative breakdown" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative catabolism" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative degradation" EXACT [GOC:TermGenie] +is_a: GO:0009056 ! catabolic process is_a: GO:1901135 ! carbohydrate derivative metabolic process -is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:63299 ! carbohydrate derivative -relationship: has_primary_input CHEBI:63299 ! carbohydrate derivative +intersection_of: has_primary_input CHEBI:63299 +relationship: has_primary_input CHEBI:63299 created_by: bf creation_date: 2012-07-12T04:05:31Z @@ -131372,11 +116733,11 @@ synonym: "carbohydrate derivative anabolism" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative biosynthesis" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative formation" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009058 ! biosynthetic process is_a: GO:1901135 ! carbohydrate derivative metabolic process -is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:63299 ! carbohydrate derivative -relationship: has_primary_output CHEBI:63299 ! carbohydrate derivative +intersection_of: has_primary_output CHEBI:63299 +relationship: has_primary_output CHEBI:63299 created_by: bf creation_date: 2012-07-12T04:05:39Z @@ -131470,8 +116831,8 @@ def: "The chemical reactions and pathways involving primary amino compound." [GO synonym: "primary amino compound metabolism" EXACT [GOC:TermGenie] is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:50994 ! primary amino compound -relationship: has_primary_input_or_output CHEBI:50994 ! primary amino compound +intersection_of: has_primary_input_or_output CHEBI:50994 +relationship: has_primary_input_or_output CHEBI:50994 created_by: bf creation_date: 2012-07-18T04:44:39Z @@ -131483,11 +116844,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of primary synonym: "primary amino compound breakdown" EXACT [GOC:TermGenie] synonym: "primary amino compound catabolism" EXACT [GOC:TermGenie] synonym: "primary amino compound degradation" EXACT [GOC:TermGenie] +is_a: GO:0009056 ! catabolic process is_a: GO:1901160 ! primary amino compound metabolic process -is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:50994 ! primary amino compound -relationship: has_primary_input CHEBI:50994 ! primary amino compound +intersection_of: has_primary_input CHEBI:50994 +relationship: has_primary_input CHEBI:50994 created_by: bf creation_date: 2012-07-18T04:45:06Z @@ -131500,11 +116861,11 @@ synonym: "primary amino compound anabolism" EXACT [GOC:TermGenie] synonym: "primary amino compound biosynthesis" EXACT [GOC:TermGenie] synonym: "primary amino compound formation" EXACT [GOC:TermGenie] synonym: "primary amino compound synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009058 ! biosynthetic process is_a: GO:1901160 ! primary amino compound metabolic process -is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:50994 ! primary amino compound -relationship: has_primary_output CHEBI:50994 ! primary amino compound +intersection_of: has_primary_output CHEBI:50994 +relationship: has_primary_output CHEBI:50994 created_by: bf creation_date: 2012-07-18T04:45:14Z @@ -131630,31 +116991,6 @@ relationship: positively_regulates GO:0001677 ! formation of translation initiat created_by: ss creation_date: 2012-07-25T02:27:29Z -[Term] -id: GO:1901197 -name: positive regulation of calcium-mediated signaling involved in cellular response to calcium ion -namespace: biological_process -def: "Any positive regulation of calcium-mediated signaling that is involved in cellular response to calcium ion." [GOC:TermGenie] -synonym: "activation of calcium-mediated signaling involved in cellular response to Ca2+ ion" NARROW [GOC:TermGenie] -synonym: "activation of calcium-mediated signaling involved in cellular response to calcium ion" NARROW [GOC:TermGenie] -synonym: "positive regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion" EXACT [GOC:TermGenie] -synonym: "positive regulation of calcium-mediated signalling involved in cellular response to Ca2+ ion" EXACT [GOC:TermGenie] -synonym: "positive regulation of calcium-mediated signalling involved in cellular response to calcium ion" EXACT [GOC:TermGenie] -synonym: "stimulation of calcium-mediated signaling involved in cellular response to Ca2+ ion" NARROW [GOC:TermGenie] -synonym: "stimulation of calcium-mediated signaling involved in cellular response to calcium ion" NARROW [GOC:TermGenie] -synonym: "up regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion" EXACT [GOC:TermGenie] -synonym: "up regulation of calcium-mediated signaling involved in cellular response to calcium ion" EXACT [GOC:TermGenie] -synonym: "up-regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion" EXACT [GOC:TermGenie] -synonym: "up-regulation of calcium-mediated signaling involved in response to calcium ion" EXACT [GOC:TermGenie] -synonym: "upregulation of calcium-mediated signaling involved in cellular response to Ca2+ ion" EXACT [GOC:TermGenie] -synonym: "upregulation of calcium-mediated signaling involved in cellular response to calcium ion" EXACT [GOC:TermGenie] -is_a: GO:0050850 ! positive regulation of calcium-mediated signaling -intersection_of: GO:0050850 ! positive regulation of calcium-mediated signaling -intersection_of: part_of GO:0071277 ! cellular response to calcium ion -relationship: part_of GO:0071277 ! cellular response to calcium ion -created_by: al -creation_date: 2012-07-27T10:57:56Z - [Term] id: GO:1901201 name: regulation of extracellular matrix assembly @@ -131999,10 +117335,10 @@ id: GO:1901264 name: carbohydrate derivative transport namespace: biological_process def: "The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf, GOC:jl, GOC:TermGenie] -is_a: GO:0071702 ! organic substance transport +is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:63299 ! carbohydrate derivative -relationship: has_primary_input CHEBI:63299 ! carbohydrate derivative +intersection_of: has_primary_input CHEBI:63299 +relationship: has_primary_input CHEBI:63299 created_by: bf creation_date: 2012-08-16T14:51:22Z @@ -132097,10 +117433,10 @@ id: GO:1901338 name: catecholamine binding namespace: molecular_function def: "Binding to catecholamine." [GOC:TermGenie] -is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:33567 ! catecholamine -relationship: has_input CHEBI:33567 ! catecholamine +intersection_of: has_input CHEBI:33567 +relationship: has_input CHEBI:33567 created_by: bf creation_date: 2012-09-03T14:08:44Z @@ -132148,8 +117484,8 @@ def: "The chemical reactions and pathways involving organic cyclic compound." [G synonym: "organic cyclic compound metabolism" EXACT [GOC:TermGenie] is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:33832 ! organic cyclic compound -relationship: has_primary_input_or_output CHEBI:33832 ! organic cyclic compound +intersection_of: has_primary_input_or_output CHEBI:33832 +relationship: has_primary_input_or_output CHEBI:33832 created_by: bf creation_date: 2012-09-14T09:03:51Z @@ -132161,11 +117497,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of organic synonym: "organic cyclic compound breakdown" EXACT [GOC:TermGenie] synonym: "organic cyclic compound catabolism" EXACT [GOC:TermGenie] synonym: "organic cyclic compound degradation" EXACT [GOC:TermGenie] +is_a: GO:0009056 ! catabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process -is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:33832 ! organic cyclic compound -relationship: has_primary_input CHEBI:33832 ! organic cyclic compound +intersection_of: has_primary_input CHEBI:33832 +relationship: has_primary_input CHEBI:33832 created_by: bf creation_date: 2012-09-14T09:05:04Z @@ -132181,8 +117517,8 @@ synonym: "organic cyclic compound synthesis" EXACT [GOC:TermGenie] is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:33832 ! organic cyclic compound -relationship: has_primary_output CHEBI:33832 ! organic cyclic compound +intersection_of: has_primary_output CHEBI:33832 +relationship: has_primary_output CHEBI:33832 created_by: bf creation_date: 2012-09-14T09:05:22Z @@ -132193,36 +117529,11 @@ namespace: molecular_function def: "Binding to heterocyclic compound." [GOC:TermGenie] is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:5686 ! heterocyclic compound -relationship: has_input CHEBI:5686 ! heterocyclic compound +intersection_of: has_input CHEBI:5686 +relationship: has_input CHEBI:5686 created_by: bf creation_date: 2012-09-14T13:53:50Z -[Term] -id: GO:1901374 -name: acetate ester transport -namespace: biological_process -def: "The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:TermGenie] -is_a: GO:0071702 ! organic substance transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:47622 ! acetate ester -relationship: has_primary_input CHEBI:47622 ! acetate ester -created_by: bf -creation_date: 2012-09-28T10:42:13Z - -[Term] -id: GO:1901375 -name: acetate ester transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of an acetate ester from one side of a membrane to the other." [GOC:TermGenie] -is_a: GO:0022857 ! transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:47622 ! acetate ester -relationship: has_primary_input CHEBI:47622 ! acetate ester -relationship: part_of GO:1901374 ! acetate ester transport -created_by: bf -creation_date: 2012-09-28T10:47:08Z - [Term] id: GO:1901382 name: regulation of chorionic trophoblast cell proliferation @@ -132284,7 +117595,6 @@ synonym: "regulation of voltage-dependent calcium channel activity" EXACT [GOC:T synonym: "regulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] synonym: "regulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity -is_a: GO:2001257 ! regulation of cation channel activity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005245 ! voltage-gated calcium channel activity relationship: regulates GO:0005245 ! voltage-gated calcium channel activity @@ -132347,7 +117657,6 @@ synonym: "negative regulation of voltage-gated calcium ion channel activity" EXA synonym: "negative regulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] is_a: GO:1901020 ! negative regulation of calcium ion transmembrane transporter activity is_a: GO:1901385 ! regulation of voltage-gated calcium channel activity -is_a: GO:2001258 ! negative regulation of cation channel activity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0005245 ! voltage-gated calcium channel activity relationship: negatively_regulates GO:0005245 ! voltage-gated calcium channel activity @@ -132410,507 +117719,12 @@ synonym: "upregulation of voltage-gated calcium ion channel activity" EXACT [GOC synonym: "upregulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] is_a: GO:1901021 ! positive regulation of calcium ion transmembrane transporter activity is_a: GO:1901385 ! regulation of voltage-gated calcium channel activity -is_a: GO:2001259 ! positive regulation of cation channel activity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0005245 ! voltage-gated calcium channel activity relationship: positively_regulates GO:0005245 ! voltage-gated calcium channel activity created_by: vk creation_date: 2012-10-01T10:35:32Z -[Term] -id: GO:1901401 -name: regulation of tetrapyrrole metabolic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie] -synonym: "regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] -is_a: GO:0031323 ! regulation of cellular metabolic process -is_a: GO:0051171 ! regulation of nitrogen compound metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0033013 ! tetrapyrrole metabolic process -relationship: regulates GO:0033013 ! tetrapyrrole metabolic process -created_by: tt -creation_date: 2012-10-01T14:34:03Z - -[Term] -id: GO:1901402 -name: negative regulation of tetrapyrrole metabolic process -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie] -synonym: "down regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] -synonym: "down regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] -synonym: "down-regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] -synonym: "down-regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] -synonym: "downregulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] -synonym: "downregulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] -synonym: "inhibition of tetrapyrrole metabolic process" NARROW [GOC:TermGenie] -synonym: "inhibition of tetrapyrrole metabolism" EXACT [GOC:TermGenie] -synonym: "negative regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] -is_a: GO:0031324 ! negative regulation of cellular metabolic process -is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process -is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0033013 ! tetrapyrrole metabolic process -relationship: negatively_regulates GO:0033013 ! tetrapyrrole metabolic process -created_by: tt -creation_date: 2012-10-01T14:35:11Z - -[Term] -id: GO:1901403 -name: positive regulation of tetrapyrrole metabolic process -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie] -synonym: "activation of tetrapyrrole metabolic process" NARROW [GOC:TermGenie] -synonym: "activation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] -synonym: "positive regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] -synonym: "up regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] -synonym: "up regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] -synonym: "up-regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] -synonym: "up-regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] -synonym: "upregulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] -synonym: "upregulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] -is_a: GO:0031325 ! positive regulation of cellular metabolic process -is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process -is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0033013 ! tetrapyrrole metabolic process -relationship: positively_regulates GO:0033013 ! tetrapyrrole metabolic process -created_by: tt -creation_date: 2012-10-01T14:35:29Z - -[Term] -id: GO:1901404 -name: regulation of tetrapyrrole catabolic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] -synonym: "regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] -synonym: "regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] -synonym: "regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] -is_a: GO:0031329 ! regulation of cellular catabolic process -is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0033015 ! tetrapyrrole catabolic process -relationship: regulates GO:0033015 ! tetrapyrrole catabolic process -created_by: tt -creation_date: 2012-10-01T14:38:12Z - -[Term] -id: GO:1901405 -name: negative regulation of tetrapyrrole catabolic process -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] -synonym: "down regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] -synonym: "down regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] -synonym: "down regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] -synonym: "down regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] -synonym: "down-regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] -synonym: "down-regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] -synonym: "down-regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] -synonym: "down-regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] -synonym: "downregulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] -synonym: "downregulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] -synonym: "downregulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] -synonym: "downregulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] -synonym: "inhibition of tetrapyrrole breakdown" EXACT [GOC:TermGenie] -synonym: "inhibition of tetrapyrrole catabolic process" NARROW [GOC:TermGenie] -synonym: "inhibition of tetrapyrrole catabolism" EXACT [GOC:TermGenie] -synonym: "inhibition of tetrapyrrole degradation" EXACT [GOC:TermGenie] -synonym: "negative regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] -synonym: "negative regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] -synonym: "negative regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] -is_a: GO:0031330 ! negative regulation of cellular catabolic process -is_a: GO:1901402 ! negative regulation of tetrapyrrole metabolic process -is_a: GO:1901404 ! regulation of tetrapyrrole catabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0033015 ! tetrapyrrole catabolic process -relationship: negatively_regulates GO:0033015 ! tetrapyrrole catabolic process -created_by: tt -creation_date: 2012-10-01T14:39:22Z - -[Term] -id: GO:1901406 -name: positive regulation of tetrapyrrole catabolic process -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] -synonym: "activation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] -synonym: "activation of tetrapyrrole catabolic process" NARROW [GOC:TermGenie] -synonym: "activation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] -synonym: "activation of tetrapyrrole degradation" EXACT [GOC:TermGenie] -synonym: "positive regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] -synonym: "positive regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] -synonym: "positive regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] -synonym: "up regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] -synonym: "up regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] -synonym: "up regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] -synonym: "up regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] -synonym: "up-regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] -synonym: "up-regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] -synonym: "up-regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] -synonym: "up-regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] -synonym: "upregulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] -synonym: "upregulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] -synonym: "upregulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] -synonym: "upregulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] -is_a: GO:0031331 ! positive regulation of cellular catabolic process -is_a: GO:1901403 ! positive regulation of tetrapyrrole metabolic process -is_a: GO:1901404 ! regulation of tetrapyrrole catabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0033015 ! tetrapyrrole catabolic process -relationship: positively_regulates GO:0033015 ! tetrapyrrole catabolic process -created_by: tt -creation_date: 2012-10-01T14:39:40Z - -[Term] -id: GO:1901410 -name: regulation of tetrapyrrole biosynthetic process from glutamate -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate." [GOC:mengo_curators, GOC:TermGenie] -synonym: "regulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] -synonym: "regulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "regulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] -synonym: "regulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] -is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process -is_a: GO:2000211 ! regulation of glutamate metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0033526 ! tetrapyrrole biosynthetic process from glutamate -relationship: regulates GO:0033526 ! tetrapyrrole biosynthetic process from glutamate -created_by: tt -creation_date: 2012-10-01T16:20:56Z - -[Term] -id: GO:1901411 -name: negative regulation of tetrapyrrole biosynthetic process from glutamate -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate." [GOC:mengo_curators, GOC:TermGenie] -synonym: "down regulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] -synonym: "down regulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "down regulation of tetrapyrrole biosynthetic process from glutamate" EXACT [GOC:TermGenie] -synonym: "down regulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] -synonym: "down regulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "down-regulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] -synonym: "down-regulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "down-regulation of tetrapyrrole biosynthetic process from glutamate" EXACT [GOC:TermGenie] -synonym: "down-regulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] -synonym: "down-regulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "downregulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] -synonym: "downregulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "downregulation of tetrapyrrole biosynthetic process from glutamate" EXACT [GOC:TermGenie] -synonym: "downregulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] -synonym: "downregulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "inhibition of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] -synonym: "inhibition of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "inhibition of tetrapyrrole biosynthetic process from glutamate" NARROW [GOC:TermGenie] -synonym: "inhibition of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] -synonym: "inhibition of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "negative regulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] -synonym: "negative regulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "negative regulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] -synonym: "negative regulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] -is_a: GO:1901410 ! regulation of tetrapyrrole biosynthetic process from glutamate -is_a: GO:1901464 ! negative regulation of tetrapyrrole biosynthetic process -is_a: GO:2000212 ! negative regulation of glutamate metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0033526 ! tetrapyrrole biosynthetic process from glutamate -relationship: negatively_regulates GO:0033526 ! tetrapyrrole biosynthetic process from glutamate -created_by: tt -creation_date: 2012-10-01T16:22:03Z - -[Term] -id: GO:1901412 -name: positive regulation of tetrapyrrole biosynthetic process from glutamate -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate." [GOC:mengo_curators, GOC:TermGenie] -synonym: "activation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] -synonym: "activation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "activation of tetrapyrrole biosynthetic process from glutamate" NARROW [GOC:TermGenie] -synonym: "activation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] -synonym: "activation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "positive regulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] -synonym: "positive regulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "positive regulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] -synonym: "positive regulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "up regulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] -synonym: "up regulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "up regulation of tetrapyrrole biosynthetic process from glutamate" EXACT [GOC:TermGenie] -synonym: "up regulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] -synonym: "up regulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "up-regulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] -synonym: "up-regulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "up-regulation of tetrapyrrole biosynthetic process from glutamate" EXACT [GOC:TermGenie] -synonym: "up-regulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] -synonym: "up-regulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "upregulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] -synonym: "upregulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] -synonym: "upregulation of tetrapyrrole biosynthetic process from glutamate" EXACT [GOC:TermGenie] -synonym: "upregulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] -synonym: "upregulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] -is_a: GO:1901410 ! regulation of tetrapyrrole biosynthetic process from glutamate -is_a: GO:1901465 ! positive regulation of tetrapyrrole biosynthetic process -is_a: GO:2000213 ! positive regulation of glutamate metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0033526 ! tetrapyrrole biosynthetic process from glutamate -relationship: positively_regulates GO:0033526 ! tetrapyrrole biosynthetic process from glutamate -created_by: tt -creation_date: 2012-10-01T16:22:21Z - -[Term] -id: GO:1901419 -name: regulation of response to alcohol -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of response to alcohol." [GOC:mengo_curators, GOC:TermGenie] -is_a: GO:0048583 ! regulation of response to stimulus -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0097305 ! response to alcohol -relationship: regulates GO:0097305 ! response to alcohol -created_by: tt -creation_date: 2012-10-01T16:52:13Z - -[Term] -id: GO:1901420 -name: negative regulation of response to alcohol -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol." [GOC:mengo_curators, GOC:TermGenie] -synonym: "down regulation of response to alcohol" EXACT [GOC:TermGenie] -synonym: "down-regulation of response to alcohol" EXACT [GOC:TermGenie] -synonym: "downregulation of response to alcohol" EXACT [GOC:TermGenie] -synonym: "inhibition of response to alcohol" NARROW [GOC:TermGenie] -is_a: GO:0048585 ! negative regulation of response to stimulus -is_a: GO:1901419 ! regulation of response to alcohol -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0097305 ! response to alcohol -relationship: negatively_regulates GO:0097305 ! response to alcohol -created_by: tt -creation_date: 2012-10-01T16:53:25Z - -[Term] -id: GO:1901421 -name: positive regulation of response to alcohol -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of response to alcohol." [GOC:mengo_curators, GOC:TermGenie] -synonym: "activation of response to alcohol" NARROW [GOC:TermGenie] -synonym: "up regulation of response to alcohol" EXACT [GOC:TermGenie] -synonym: "up-regulation of response to alcohol" EXACT [GOC:TermGenie] -synonym: "upregulation of response to alcohol" EXACT [GOC:TermGenie] -is_a: GO:0048584 ! positive regulation of response to stimulus -is_a: GO:1901419 ! regulation of response to alcohol -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0097305 ! response to alcohol -relationship: positively_regulates GO:0097305 ! response to alcohol -created_by: tt -creation_date: 2012-10-01T16:53:42Z - -[Term] -id: GO:1901425 -name: response to formic acid -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formic acid stimulus." [GOC:mengo_curators, GOC:TermGenie] -is_a: GO:0010033 ! response to organic substance -is_a: GO:1901700 ! response to oxygen-containing compound -intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:15740 ! formate -relationship: has_input CHEBI:15740 ! formate -created_by: tt -creation_date: 2012-10-01T18:43:05Z - -[Term] -id: GO:1901457 -name: regulation of response to acetate -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] -is_a: GO:0048583 ! regulation of response to stimulus -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0010034 ! response to acetate -relationship: regulates GO:0010034 ! response to acetate -created_by: tt -creation_date: 2012-10-02T14:25:06Z - -[Term] -id: GO:1901458 -name: negative regulation of response to acetate -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] -synonym: "down regulation of response to acetate" EXACT [GOC:TermGenie] -synonym: "down-regulation of response to acetate" EXACT [GOC:TermGenie] -synonym: "downregulation of response to acetate" EXACT [GOC:TermGenie] -synonym: "inhibition of response to acetate" NARROW [GOC:TermGenie] -is_a: GO:0048585 ! negative regulation of response to stimulus -is_a: GO:1901457 ! regulation of response to acetate -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0010034 ! response to acetate -relationship: negatively_regulates GO:0010034 ! response to acetate -created_by: tt -creation_date: 2012-10-02T14:26:15Z - -[Term] -id: GO:1901459 -name: positive regulation of response to acetate -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] -synonym: "activation of response to acetate" NARROW [GOC:TermGenie] -synonym: "up regulation of response to acetate" EXACT [GOC:TermGenie] -synonym: "up-regulation of response to acetate" EXACT [GOC:TermGenie] -synonym: "upregulation of response to acetate" EXACT [GOC:TermGenie] -is_a: GO:0048584 ! positive regulation of response to stimulus -is_a: GO:1901457 ! regulation of response to acetate -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0010034 ! response to acetate -relationship: positively_regulates GO:0010034 ! response to acetate -created_by: tt -creation_date: 2012-10-02T14:26:34Z - -[Term] -id: GO:1901460 -name: regulation of response to formic acid -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of response to formic acid." [GOC:mengo_curators, GOC:TermGenie] -is_a: GO:0048583 ! regulation of response to stimulus -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:1901425 ! response to formic acid -relationship: regulates GO:1901425 ! response to formic acid -created_by: tt -creation_date: 2012-10-02T14:27:54Z - -[Term] -id: GO:1901461 -name: negative regulation of response to formic acid -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to formic acid." [GOC:mengo_curators, GOC:TermGenie] -synonym: "down regulation of response to formic acid" EXACT [GOC:TermGenie] -synonym: "down-regulation of response to formic acid" EXACT [GOC:TermGenie] -synonym: "downregulation of response to formic acid" EXACT [GOC:TermGenie] -synonym: "inhibition of response to formic acid" NARROW [GOC:TermGenie] -is_a: GO:0048585 ! negative regulation of response to stimulus -is_a: GO:1901460 ! regulation of response to formic acid -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:1901425 ! response to formic acid -relationship: negatively_regulates GO:1901425 ! response to formic acid -created_by: tt -creation_date: 2012-10-02T14:29:02Z - -[Term] -id: GO:1901462 -name: positive regulation of response to formic acid -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of response to formic acid." [GOC:mengo_curators, GOC:TermGenie] -synonym: "activation of response to formic acid" NARROW [GOC:TermGenie] -synonym: "up regulation of response to formic acid" EXACT [GOC:TermGenie] -synonym: "up-regulation of response to formic acid" EXACT [GOC:TermGenie] -synonym: "upregulation of response to formic acid" EXACT [GOC:TermGenie] -is_a: GO:0048584 ! positive regulation of response to stimulus -is_a: GO:1901460 ! regulation of response to formic acid -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:1901425 ! response to formic acid -relationship: positively_regulates GO:1901425 ! response to formic acid -created_by: tt -creation_date: 2012-10-02T14:29:20Z - -[Term] -id: GO:1901463 -name: regulation of tetrapyrrole biosynthetic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] -synonym: "regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] -synonym: "regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] -synonym: "regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] -synonym: "regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] -is_a: GO:0031326 ! regulation of cellular biosynthetic process -is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0033014 ! tetrapyrrole biosynthetic process -relationship: regulates GO:0033014 ! tetrapyrrole biosynthetic process -created_by: tt -creation_date: 2012-10-02T14:34:14Z - -[Term] -id: GO:1901464 -name: negative regulation of tetrapyrrole biosynthetic process -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] -synonym: "down regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] -synonym: "down regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] -synonym: "down regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] -synonym: "down regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] -synonym: "down regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] -synonym: "down-regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] -synonym: "down-regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] -synonym: "down-regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] -synonym: "down-regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] -synonym: "down-regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] -synonym: "downregulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] -synonym: "downregulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] -synonym: "downregulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] -synonym: "downregulation of tetrapyrrole formation" EXACT [GOC:TermGenie] -synonym: "downregulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] -synonym: "inhibition of tetrapyrrole anabolism" EXACT [GOC:TermGenie] -synonym: "inhibition of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] -synonym: "inhibition of tetrapyrrole biosynthetic process" NARROW [GOC:TermGenie] -synonym: "inhibition of tetrapyrrole formation" EXACT [GOC:TermGenie] -synonym: "inhibition of tetrapyrrole synthesis" EXACT [GOC:TermGenie] -synonym: "negative regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] -synonym: "negative regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] -synonym: "negative regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] -synonym: "negative regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] -is_a: GO:0031327 ! negative regulation of cellular biosynthetic process -is_a: GO:1901402 ! negative regulation of tetrapyrrole metabolic process -is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0033014 ! tetrapyrrole biosynthetic process -relationship: negatively_regulates GO:0033014 ! tetrapyrrole biosynthetic process -created_by: tt -creation_date: 2012-10-02T14:35:26Z - -[Term] -id: GO:1901465 -name: positive regulation of tetrapyrrole biosynthetic process -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] -synonym: "activation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] -synonym: "activation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] -synonym: "activation of tetrapyrrole biosynthetic process" NARROW [GOC:TermGenie] -synonym: "activation of tetrapyrrole formation" EXACT [GOC:TermGenie] -synonym: "activation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] -synonym: "positive regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] -synonym: "positive regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] -synonym: "positive regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] -synonym: "positive regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] -synonym: "up regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] -synonym: "up regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] -synonym: "up regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] -synonym: "up regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] -synonym: "up regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] -synonym: "up-regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] -synonym: "up-regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] -synonym: "up-regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] -synonym: "up-regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] -synonym: "up-regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] -synonym: "upregulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] -synonym: "upregulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] -synonym: "upregulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] -synonym: "upregulation of tetrapyrrole formation" EXACT [GOC:TermGenie] -synonym: "upregulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] -is_a: GO:0031328 ! positive regulation of cellular biosynthetic process -is_a: GO:1901403 ! positive regulation of tetrapyrrole metabolic process -is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0033014 ! tetrapyrrole biosynthetic process -relationship: positively_regulates GO:0033014 ! tetrapyrrole biosynthetic process -created_by: tt -creation_date: 2012-10-02T14:35:43Z - -[Term] -id: GO:1901474 -name: azole transmembrane transporter activity -namespace: molecular_function -alt_id: GO:0045118 -def: "Enables the directed movement of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other." [GOC:go_curators, ISBN:3527307206, Wikipedia:Azole] -synonym: "azole transporter activity" RELATED [] -is_a: GO:0022857 ! transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:68452 ! azole -relationship: has_primary_input CHEBI:68452 ! azole -relationship: part_of GO:0045117 ! azole transmembrane transport -created_by: tb -creation_date: 2012-10-04T20:00:27Z - [Term] id: GO:1901490 name: regulation of lymphangiogenesis @@ -132976,8 +117790,8 @@ def: "Enables the transfer of carbohydrate derivative from one side of a membran synonym: "carbohydrate derivative transporter activity" RELATED [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:63299 ! carbohydrate derivative -relationship: has_primary_input CHEBI:63299 ! carbohydrate derivative +intersection_of: has_primary_input CHEBI:63299 +relationship: has_primary_input CHEBI:63299 relationship: part_of GO:1901264 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! carbohydrate derivative transport created_by: pr creation_date: 2012-10-17T10:31:22Z @@ -133130,8 +117944,8 @@ synonym: "organonitrogen compound metabolism" EXACT [GOC:TermGenie] is_a: GO:0006807 ! nitrogen compound metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:35352 ! organonitrogen compound -relationship: has_primary_input_or_output CHEBI:35352 ! organonitrogen compound +intersection_of: has_primary_input_or_output CHEBI:35352 +relationship: has_primary_input_or_output CHEBI:35352 created_by: pr creation_date: 2012-11-04T15:17:52Z @@ -133143,11 +117957,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of organoni synonym: "organonitrogen compound breakdown" EXACT [GOC:TermGenie] synonym: "organonitrogen compound catabolism" EXACT [GOC:TermGenie] synonym: "organonitrogen compound degradation" EXACT [GOC:TermGenie] +is_a: GO:0009056 ! catabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process -is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:35352 ! organonitrogen compound -relationship: has_primary_input CHEBI:35352 ! organonitrogen compound +intersection_of: has_primary_input CHEBI:35352 +relationship: has_primary_input CHEBI:35352 created_by: pr creation_date: 2012-11-04T15:17:56Z @@ -133163,8 +117977,8 @@ synonym: "organonitrogen compound synthesis" EXACT [GOC:TermGenie] is_a: GO:1901564 ! organonitrogen compound metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:35352 ! organonitrogen compound -relationship: has_primary_output CHEBI:35352 ! organonitrogen compound +intersection_of: has_primary_output CHEBI:35352 +relationship: has_primary_output CHEBI:35352 created_by: pr creation_date: 2012-11-04T15:18:00Z @@ -133183,8 +117997,8 @@ synonym: "organic substance degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:50860 ! organic molecular entity -relationship: has_primary_input CHEBI:50860 ! organic molecular entity +intersection_of: has_primary_input CHEBI:50860 +relationship: has_primary_input CHEBI:50860 created_by: pr creation_date: 2012-11-05T11:04:36Z @@ -133205,101 +118019,11 @@ synonym: "organic substance synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:50860 ! organic molecular entity -relationship: has_primary_output CHEBI:50860 ! organic molecular entity +intersection_of: has_primary_output CHEBI:50860 +relationship: has_primary_output CHEBI:50860 created_by: pr creation_date: 2012-11-05T11:04:40Z -[Term] -id: GO:1901577 -name: regulation of alkane biosynthetic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of alkane biosynthetic process." [GOC:TermGenie] -synonym: "regulation of alkane anabolism" EXACT [GOC:TermGenie] -synonym: "regulation of alkane biosynthesis" EXACT [GOC:TermGenie] -synonym: "regulation of alkane formation" EXACT [GOC:TermGenie] -synonym: "regulation of alkane synthesis" EXACT [GOC:TermGenie] -is_a: GO:0031326 ! regulation of cellular biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0043447 ! alkane biosynthetic process -relationship: regulates GO:0043447 ! alkane biosynthetic process -created_by: dhl -creation_date: 2012-11-05T21:54:06Z - -[Term] -id: GO:1901578 -name: negative regulation of alkane biosynthetic process -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of alkane biosynthetic process." [GOC:TermGenie] -synonym: "down regulation of alkane anabolism" EXACT [GOC:TermGenie] -synonym: "down regulation of alkane biosynthesis" EXACT [GOC:TermGenie] -synonym: "down regulation of alkane biosynthetic process" EXACT [GOC:TermGenie] -synonym: "down regulation of alkane formation" EXACT [GOC:TermGenie] -synonym: "down regulation of alkane synthesis" EXACT [GOC:TermGenie] -synonym: "down-regulation of alkane anabolism" EXACT [GOC:TermGenie] -synonym: "down-regulation of alkane biosynthesis" EXACT [GOC:TermGenie] -synonym: "down-regulation of alkane biosynthetic process" EXACT [GOC:TermGenie] -synonym: "down-regulation of alkane formation" EXACT [GOC:TermGenie] -synonym: "down-regulation of alkane synthesis" EXACT [GOC:TermGenie] -synonym: "downregulation of alkane anabolism" EXACT [GOC:TermGenie] -synonym: "downregulation of alkane biosynthesis" EXACT [GOC:TermGenie] -synonym: "downregulation of alkane biosynthetic process" EXACT [GOC:TermGenie] -synonym: "downregulation of alkane formation" EXACT [GOC:TermGenie] -synonym: "downregulation of alkane synthesis" EXACT [GOC:TermGenie] -synonym: "inhibition of alkane anabolism" EXACT [GOC:TermGenie] -synonym: "inhibition of alkane biosynthesis" EXACT [GOC:TermGenie] -synonym: "inhibition of alkane biosynthetic process" NARROW [GOC:TermGenie] -synonym: "inhibition of alkane formation" EXACT [GOC:TermGenie] -synonym: "inhibition of alkane synthesis" EXACT [GOC:TermGenie] -synonym: "negative regulation of alkane anabolism" EXACT [GOC:TermGenie] -synonym: "negative regulation of alkane biosynthesis" EXACT [GOC:TermGenie] -synonym: "negative regulation of alkane formation" EXACT [GOC:TermGenie] -synonym: "negative regulation of alkane synthesis" EXACT [GOC:TermGenie] -is_a: GO:0031327 ! negative regulation of cellular biosynthetic process -is_a: GO:1901577 ! regulation of alkane biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0043447 ! alkane biosynthetic process -relationship: negatively_regulates GO:0043447 ! alkane biosynthetic process -created_by: dhl -creation_date: 2012-11-05T21:54:11Z - -[Term] -id: GO:1901579 -name: positive regulation of alkane biosynthetic process -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of alkane biosynthetic process." [GOC:TermGenie] -synonym: "activation of alkane anabolism" EXACT [GOC:TermGenie] -synonym: "activation of alkane biosynthesis" EXACT [GOC:TermGenie] -synonym: "activation of alkane biosynthetic process" NARROW [GOC:TermGenie] -synonym: "activation of alkane formation" EXACT [GOC:TermGenie] -synonym: "activation of alkane synthesis" EXACT [GOC:TermGenie] -synonym: "positive regulation of alkane anabolism" EXACT [GOC:TermGenie] -synonym: "positive regulation of alkane biosynthesis" EXACT [GOC:TermGenie] -synonym: "positive regulation of alkane formation" EXACT [GOC:TermGenie] -synonym: "positive regulation of alkane synthesis" EXACT [GOC:TermGenie] -synonym: "up regulation of alkane anabolism" EXACT [GOC:TermGenie] -synonym: "up regulation of alkane biosynthesis" EXACT [GOC:TermGenie] -synonym: "up regulation of alkane biosynthetic process" EXACT [GOC:TermGenie] -synonym: "up regulation of alkane formation" EXACT [GOC:TermGenie] -synonym: "up regulation of alkane synthesis" EXACT [GOC:TermGenie] -synonym: "up-regulation of alkane anabolism" EXACT [GOC:TermGenie] -synonym: "up-regulation of alkane biosynthesis" EXACT [GOC:TermGenie] -synonym: "up-regulation of alkane biosynthetic process" EXACT [GOC:TermGenie] -synonym: "up-regulation of alkane formation" EXACT [GOC:TermGenie] -synonym: "up-regulation of alkane synthesis" EXACT [GOC:TermGenie] -synonym: "upregulation of alkane anabolism" EXACT [GOC:TermGenie] -synonym: "upregulation of alkane biosynthesis" EXACT [GOC:TermGenie] -synonym: "upregulation of alkane biosynthetic process" EXACT [GOC:TermGenie] -synonym: "upregulation of alkane formation" EXACT [GOC:TermGenie] -synonym: "upregulation of alkane synthesis" EXACT [GOC:TermGenie] -is_a: GO:0031328 ! positive regulation of cellular biosynthetic process -is_a: GO:1901577 ! regulation of alkane biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0043447 ! alkane biosynthetic process -relationship: positively_regulates GO:0043447 ! alkane biosynthetic process -created_by: dhl -creation_date: 2012-11-05T21:54:19Z - [Term] id: GO:1901588 name: dendritic microtubule @@ -133339,8 +118063,8 @@ def: "The chemical reactions and pathways involving an alpha-amino acid." [GOC:T synonym: "alpha-amino acid metabolism" EXACT [GOC:TermGenie] is_a: GO:0006520 ! amino acid metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:78608 ! alpha-amino acid zwitterion -relationship: has_primary_input_or_output CHEBI:78608 ! alpha-amino acid zwitterion +intersection_of: has_primary_input_or_output CHEBI:78608 +relationship: has_primary_input_or_output CHEBI:78608 created_by: tb creation_date: 2012-11-08T17:39:50Z @@ -133352,11 +118076,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of an alpha synonym: "alpha-amino acid breakdown" EXACT [GOC:TermGenie] synonym: "alpha-amino acid catabolism" EXACT [GOC:TermGenie] synonym: "alpha-amino acid degradation" EXACT [GOC:TermGenie] -is_a: GO:1901575 ! organic substance catabolic process +is_a: GO:0009056 ! catabolic process is_a: GO:1901605 ! alpha-amino acid metabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:78608 ! alpha-amino acid zwitterion -relationship: has_primary_input CHEBI:78608 ! alpha-amino acid zwitterion +intersection_of: has_primary_input CHEBI:78608 +relationship: has_primary_input CHEBI:78608 created_by: tb creation_date: 2012-11-08T17:39:54Z @@ -133372,8 +118096,8 @@ synonym: "alpha-amino acid synthesis" EXACT [GOC:TermGenie] is_a: GO:0008652 ! amino acid biosynthetic process is_a: GO:1901605 ! alpha-amino acid metabolic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:78608 ! alpha-amino acid zwitterion -relationship: has_primary_output CHEBI:78608 ! alpha-amino acid zwitterion +intersection_of: has_primary_output CHEBI:78608 +relationship: has_primary_output CHEBI:78608 created_by: tb creation_date: 2012-11-08T17:39:58Z @@ -133526,8 +118250,8 @@ def: "The chemical reactions and pathways involving organic hydroxy compound." [ synonym: "organic hydroxy compound metabolism" EXACT [GOC:TermGenie] is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:33822 ! organic hydroxy compound -relationship: has_primary_input_or_output CHEBI:33822 ! organic hydroxy compound +intersection_of: has_primary_input_or_output CHEBI:33822 +relationship: has_primary_input_or_output CHEBI:33822 created_by: pr creation_date: 2012-11-13T12:54:27Z @@ -133539,11 +118263,11 @@ def: "The chemical reactions and pathways resulting in the breakdown of organic synonym: "organic hydroxy compound breakdown" EXACT [GOC:TermGenie] synonym: "organic hydroxy compound catabolism" EXACT [GOC:TermGenie] synonym: "organic hydroxy compound degradation" EXACT [GOC:TermGenie] -is_a: GO:1901575 ! organic substance catabolic process +is_a: GO:0009056 ! catabolic process is_a: GO:1901615 ! organic hydroxy compound metabolic process intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:33822 ! organic hydroxy compound -relationship: has_primary_input CHEBI:33822 ! organic hydroxy compound +intersection_of: has_primary_input CHEBI:33822 +relationship: has_primary_input CHEBI:33822 created_by: pr creation_date: 2012-11-13T12:54:31Z @@ -133559,8 +118283,8 @@ synonym: "organic hydroxy compound synthesis" EXACT [GOC:TermGenie] is_a: GO:1901576 ! organic substance biosynthetic process is_a: GO:1901615 ! organic hydroxy compound metabolic process intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:33822 ! organic hydroxy compound -relationship: has_primary_output CHEBI:33822 ! organic hydroxy compound +intersection_of: has_primary_output CHEBI:33822 +relationship: has_primary_output CHEBI:33822 created_by: pr creation_date: 2012-11-13T12:54:36Z @@ -133571,8 +118295,8 @@ namespace: molecular_function def: "Enables the transfer of organic hydroxy compound from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:33822 ! organic hydroxy compound -relationship: has_primary_input CHEBI:33822 ! organic hydroxy compound +intersection_of: has_primary_input CHEBI:33822 +relationship: has_primary_input CHEBI:33822 created_by: pr creation_date: 2012-11-13T12:59:01Z @@ -133718,11 +118442,10 @@ id: GO:1901652 name: response to peptide namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus." [GOC:pr, GOC:TermGenie] -is_a: GO:0010243 ! response to organonitrogen compound -is_a: GO:1901700 ! response to oxygen-containing compound +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:16670 ! peptide -relationship: has_input CHEBI:16670 ! peptide +intersection_of: has_input CHEBI:16670 +relationship: has_input CHEBI:16670 created_by: pr creation_date: 2012-11-20T09:45:15Z @@ -133731,11 +118454,10 @@ id: GO:1901653 name: cellular response to peptide namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus." [GOC:pr, GOC:TermGenie] -is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:1901652 ! response to peptide -is_a: GO:1901701 ! cellular response to oxygen-containing compound intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:16670 ! peptide +intersection_of: has_input CHEBI:16670 created_by: pr creation_date: 2012-11-20T09:45:19Z @@ -133747,10 +118469,9 @@ alt_id: GO:1990369 def: "A response that results in a state of tolerance to ketone." [GOC:mengo_curators, PMID:23356676] synonym: "process resulting in tolerance to ketone" NARROW [] is_a: GO:0010033 ! response to organic substance -is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:17087 ! ketone -relationship: has_input CHEBI:17087 ! ketone +intersection_of: has_input CHEBI:17087 +relationship: has_input CHEBI:17087 created_by: pr creation_date: 2012-11-20T10:55:47Z @@ -133759,10 +118480,10 @@ id: GO:1901655 name: cellular response to ketone namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus." [GOC:pr, GOC:TermGenie] +is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:1901654 ! response to ketone -is_a: GO:1901701 ! cellular response to oxygen-containing compound intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:17087 ! ketone +intersection_of: has_input CHEBI:17087 created_by: pr creation_date: 2012-11-20T10:55:51Z @@ -133784,32 +118505,6 @@ relationship: negatively_regulates GO:0014901 ! satellite cell activation involv created_by: dph creation_date: 2012-11-21T16:21:11Z -[Term] -id: GO:1901681 -name: sulfur compound binding -namespace: molecular_function -def: "Binding to a sulfur compound." [GOC:pr, GOC:TermGenie] -synonym: "sulfur molecular entity binding" EXACT [] -is_a: GO:0005488 ! binding -intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:26835 ! sulfur molecular entity -relationship: has_input CHEBI:26835 ! sulfur molecular entity -created_by: pr -creation_date: 2012-11-26T20:45:23Z - -[Term] -id: GO:1901682 -name: sulfur compound transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of a sulfur compound from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] -synonym: "sulfur molecular entity transmembrane transporter activity" EXACT [] -is_a: GO:0022857 ! transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:26835 ! sulfur molecular entity -relationship: has_primary_input CHEBI:26835 ! sulfur molecular entity -created_by: pr -creation_date: 2012-11-26T20:45:29Z - [Term] id: GO:1901692 name: regulation of compound eye retinal cell apoptotic process @@ -133865,10 +118560,10 @@ name: response to nitrogen compound namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus." [GOC:pr, GOC:TermGenie] synonym: "response to nitrogen molecular entity" EXACT [] -is_a: GO:0042221 ! response to chemical +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:51143 ! nitrogen molecular entity -relationship: has_input CHEBI:51143 ! nitrogen molecular entity +intersection_of: has_input CHEBI:51143 +relationship: has_input CHEBI:51143 created_by: pr creation_date: 2012-12-13T15:06:08Z @@ -133881,7 +118576,7 @@ synonym: "cellular response to nitrogen molecular entity" EXACT [] is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:51143 ! nitrogen molecular entity +intersection_of: has_input CHEBI:51143 created_by: pr creation_date: 2012-12-13T15:06:13Z @@ -133893,8 +118588,8 @@ def: "Any process that results in a change in state or activity of a cell or an synonym: "response to oxygen molecular entity" EXACT [] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:25806 ! oxygen molecular entity -relationship: has_input CHEBI:25806 ! oxygen molecular entity +intersection_of: has_input CHEBI:25806 +relationship: has_input CHEBI:25806 created_by: pr creation_date: 2012-12-13T15:11:37Z @@ -133907,22 +118602,10 @@ synonym: "cellular response to oxygen molecular entity" EXACT [] is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:25806 ! oxygen molecular entity +intersection_of: has_input CHEBI:25806 created_by: pr creation_date: 2012-12-13T15:11:42Z -[Term] -id: GO:1901702 -name: salt transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of salt from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] -is_a: GO:0022857 ! transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:24866 ! salt -relationship: has_primary_input CHEBI:24866 ! salt -created_by: pr -creation_date: 2012-12-13T15:14:47Z - [Term] id: GO:1901706 name: mesenchymal cell differentiation involved in bone development @@ -134399,19 +119082,6 @@ relationship: positively_regulates GO:0061325 ! cell proliferation involved in o created_by: dph creation_date: 2013-02-20T20:30:31Z -[Term] -id: GO:1902001 -name: fatty acid transmembrane transport -namespace: biological_process -def: "The process in which a fatty acid is transported across a membrane." [GOC:rb, GOC:TermGenie, PMID:9395310] -is_a: GO:0015908 ! fatty acid transport -is_a: GO:1905039 ! carboxylic acid transmembrane transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:28868 ! fatty acid anion -intersection_of: results_in_transport_across GO:0016020 ! membrane -created_by: pr -creation_date: 2013-03-21T09:57:00Z - [Term] id: GO:1902017 name: regulation of cilium assembly @@ -134488,6 +119158,18 @@ relationship: negatively_regulates GO:0060285 ! cilium-dependent cell motility created_by: jl creation_date: 2013-03-27T14:42:42Z +[Term] +id: GO:1902024 +name: L-histidine transport +namespace: biological_process +def: "The directed movement of a L-histidine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:kmv, GOC:TermGenie, PMID:22822152] +is_a: GO:0015802 ! basic amino acid transport +intersection_of: GO:0015802 ! basic amino acid transport +intersection_of: has_primary_input CHEBI:57595 +relationship: has_primary_input CHEBI:57595 +created_by: kmv +creation_date: 2013-03-27T16:09:15Z + [Term] id: GO:1902033 name: regulation of hematopoietic stem cell proliferation @@ -134629,30 +119311,16 @@ created_by: ss creation_date: 2013-04-02T05:19:19Z [Term] -id: GO:1902074 -name: response to salt +id: GO:1902065 +name: response to L-glutamate namespace: biological_process -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus." [GOC:mls, GOC:TermGenie, PMID:16666921] -synonym: "response to salinity" NARROW [GOC:mls] -is_a: GO:0042221 ! response to chemical +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus." [GOC:TermGenie, PMID:23574009] +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:24866 ! salt -relationship: has_input CHEBI:24866 ! salt -created_by: mls -creation_date: 2013-04-22T15:41:57Z - -[Term] -id: GO:1902075 -name: cellular response to salt -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus." [GOC:mls, GOC:TermGenie, PMID:16666921] -synonym: "cellular response to salinity" NARROW [GOC:mls] -is_a: GO:0070887 ! cellular response to chemical stimulus -is_a: GO:1902074 ! response to salt -intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:24866 ! salt -created_by: mls -creation_date: 2013-04-22T15:42:02Z +intersection_of: has_input CHEBI:29985 +relationship: has_input CHEBI:29985 +created_by: tb +creation_date: 2013-04-16T21:21:14Z [Term] id: GO:1902076 @@ -134841,19 +119509,6 @@ relationship: positively_regulates GO:0070925 ! organelle assembly created_by: pr creation_date: 2013-05-14T09:43:36Z -[Term] -id: GO:1902170 -name: cellular response to reactive nitrogen species -namespace: biological_process -alt_id: GO:1990106 -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus." [GOC:sl, GOC:TermGenie, PMID:22504638] -is_a: GO:1901699 ! cellular response to nitrogen compound -intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:62764 ! reactive nitrogen species -relationship: has_input CHEBI:62764 ! reactive nitrogen species -created_by: tb -creation_date: 2013-05-23T00:23:59Z - [Term] id: GO:1902172 name: regulation of keratinocyte apoptotic process @@ -135195,66 +119850,6 @@ relationship: regulates GO:0006325 ! chromatin organization created_by: bf creation_date: 2013-07-01T13:21:52Z -[Term] -id: GO:1902305 -name: regulation of sodium ion transmembrane transport -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] -synonym: "regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] -is_a: GO:0002028 ! regulation of sodium ion transport -is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0035725 ! sodium ion transmembrane transport -relationship: regulates GO:0035725 ! sodium ion transmembrane transport -created_by: rl -creation_date: 2013-07-18T13:33:53Z - -[Term] -id: GO:1902306 -name: negative regulation of sodium ion transmembrane transport -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] -synonym: "down regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] -synonym: "down regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] -synonym: "down-regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] -synonym: "down-regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] -synonym: "downregulation of sodium ion membrane transport" EXACT [GOC:TermGenie] -synonym: "downregulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] -synonym: "inhibition of sodium ion membrane transport" NARROW [GOC:TermGenie] -synonym: "inhibition of sodium ion transmembrane transport" NARROW [GOC:TermGenie] -synonym: "negative regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] -is_a: GO:0010766 ! negative regulation of sodium ion transport -is_a: GO:1902305 ! regulation of sodium ion transmembrane transport -is_a: GO:1904063 ! negative regulation of cation transmembrane transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0035725 ! sodium ion transmembrane transport -relationship: negatively_regulates GO:0035725 ! sodium ion transmembrane transport -created_by: rl -creation_date: 2013-07-18T13:34:01Z - -[Term] -id: GO:1902307 -name: positive regulation of sodium ion transmembrane transport -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] -synonym: "activation of sodium ion membrane transport" NARROW [GOC:TermGenie] -synonym: "activation of sodium ion transmembrane transport" NARROW [GOC:TermGenie] -synonym: "positive regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] -synonym: "up regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] -synonym: "up regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] -synonym: "up-regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] -synonym: "up-regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] -synonym: "upregulation of sodium ion membrane transport" EXACT [GOC:TermGenie] -synonym: "upregulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] -is_a: GO:0010765 ! positive regulation of sodium ion transport -is_a: GO:1902305 ! regulation of sodium ion transmembrane transport -is_a: GO:1904064 ! positive regulation of cation transmembrane transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0035725 ! sodium ion transmembrane transport -relationship: positively_regulates GO:0035725 ! sodium ion transmembrane transport -created_by: rl -creation_date: 2013-07-18T13:34:18Z - [Term] id: GO:1902337 name: regulation of apoptotic process involved in morphogenesis @@ -135361,18 +119956,6 @@ relationship: negatively_regulates GO:0030261 ! chromosome condensation created_by: dgf creation_date: 2013-07-29T20:54:14Z -[Term] -id: GO:1902358 -name: sulfate transmembrane transport -namespace: biological_process -def: "The directed movement of sulfate across a membrane." [GOC:dph, GOC:TermGenie, PMID:9055073] -is_a: GO:0008272 ! sulfate transport -is_a: GO:0098661 ! inorganic anion transmembrane transport -intersection_of: GO:0055085 ! transmembrane transport -intersection_of: has_primary_input CHEBI:16189 ! sulfate -created_by: dph -creation_date: 2013-08-14T14:46:04Z - [Term] id: GO:1902362 name: melanocyte apoptotic process @@ -135412,7 +119995,8 @@ synonym: "inhibition of RNA degradation" NARROW [GOC:TermGenie] synonym: "negative regulation of RNA breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA degradation" EXACT [GOC:TermGenie] -is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0009895 ! negative regulation of catabolic process +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0051253 ! negative regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006401 ! RNA catabolic process @@ -135607,18 +120191,6 @@ relationship: positively_regulates GO:0035418 ! protein localization to synapse created_by: kmv creation_date: 2013-10-25T15:09:18Z -[Term] -id: GO:1902475 -name: L-alpha-amino acid transmembrane transport -namespace: biological_process -def: "The directed movement of L-alpha-amino acid across a membrane." [GOC:kmv, GOC:TermGenie, PMID:14668347] -is_a: GO:0015807 ! L-amino acid transport -is_a: GO:0055085 ! transmembrane transport -intersection_of: GO:0055085 ! transmembrane transport -intersection_of: has_primary_input CHEBI:59869 ! L-alpha-amino acid zwitterion -created_by: kmv -creation_date: 2013-10-25T15:17:39Z - [Term] id: GO:1902482 name: regulatory T cell apoptotic process @@ -136253,8 +120825,7 @@ synonym: "negative regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA synthesis" EXACT [GOC:TermGenie] -is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process -is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0051253 ! negative regulation of RNA metabolic process is_a: GO:2001141 ! regulation of RNA biosynthetic process intersection_of: GO:0065007 ! biological regulation @@ -136292,8 +120863,7 @@ synonym: "upregulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of RNA formation" EXACT [GOC:TermGenie] synonym: "upregulation of RNA synthesis" EXACT [GOC:TermGenie] -is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process -is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0051254 ! positive regulation of RNA metabolic process is_a: GO:2001141 ! regulation of RNA biosynthetic process intersection_of: GO:0065007 ! biological regulation @@ -136528,7 +121098,7 @@ synonym: "negative regulation of proteoglycan anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of proteoglycan biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of proteoglycan formation" EXACT [GOC:TermGenie] synonym: "negative regulation of proteoglycan synthesis" EXACT [GOC:TermGenie] -is_a: GO:0010561 ! negative regulation of glycoprotein biosynthetic process +is_a: GO:0009890 ! negative regulation of biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030166 ! proteoglycan biosynthetic process relationship: negatively_regulates GO:0030166 ! proteoglycan biosynthetic process @@ -136564,7 +121134,7 @@ synonym: "upregulation of proteoglycan biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of proteoglycan biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of proteoglycan formation" EXACT [GOC:TermGenie] synonym: "upregulation of proteoglycan synthesis" EXACT [GOC:TermGenie] -is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process +is_a: GO:0009891 ! positive regulation of biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030166 ! proteoglycan biosynthetic process relationship: positively_regulates GO:0030166 ! proteoglycan biosynthetic process @@ -136726,30 +121296,6 @@ relationship: results_in_movement_of CL:0000594 ! skeletal muscle satellite cell created_by: mr creation_date: 2014-03-10T15:20:28Z -[Term] -id: GO:1902778 -name: response to alkane -namespace: biological_process -alt_id: GO:1990373 -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus." [GO_REF:0000071, GOC:mengo_curators, GOC:TermGenie, PMID:22958739, PMID:23826995] -synonym: "process resulting in tolerance to alkane" NARROW [] -is_a: GO:0010033 ! response to organic substance -intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:18310 ! alkane -relationship: has_input CHEBI:18310 ! alkane - -[Term] -id: GO:1902779 -name: cellular response to alkane -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus." [GO_REF:0000071, GOC:mengo_curators, GOC:TermGenie, PMID:22958739, PMID:23826995] -is_a: GO:0070887 ! cellular response to chemical stimulus -is_a: GO:1902778 ! response to alkane -intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:18310 ! alkane -created_by: tt -creation_date: 2014-03-21T03:18:04Z - [Term] id: GO:1902809 name: regulation of skeletal muscle fiber differentiation @@ -137262,52 +121808,6 @@ relationship: positively_regulates GO:0009880 ! embryonic pattern specification created_by: mr creation_date: 2014-04-03T15:25:26Z -[Term] -id: GO:1902882 -name: regulation of response to oxidative stress -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of response to oxidative stress." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:16899554] -is_a: GO:0080134 ! regulation of response to stress -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0006979 ! response to oxidative stress -relationship: regulates GO:0006979 ! response to oxidative stress -created_by: kmv -creation_date: 2014-04-03T20:29:52Z - -[Term] -id: GO:1902883 -name: negative regulation of response to oxidative stress -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:16899554] -synonym: "down regulation of response to oxidative stress" EXACT [GOC:TermGenie] -synonym: "down-regulation of response to oxidative stress" EXACT [GOC:TermGenie] -synonym: "downregulation of response to oxidative stress" EXACT [GOC:TermGenie] -synonym: "inhibition of response to oxidative stress" NARROW [GOC:TermGenie] -is_a: GO:0048585 ! negative regulation of response to stimulus -is_a: GO:1902882 ! regulation of response to oxidative stress -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0006979 ! response to oxidative stress -relationship: negatively_regulates GO:0006979 ! response to oxidative stress -created_by: kmv -creation_date: 2014-04-03T20:30:20Z - -[Term] -id: GO:1902884 -name: positive regulation of response to oxidative stress -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of response to oxidative stress." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:16899554] -synonym: "activation of response to oxidative stress" NARROW [GOC:TermGenie] -synonym: "up regulation of response to oxidative stress" EXACT [GOC:TermGenie] -synonym: "up-regulation of response to oxidative stress" EXACT [GOC:TermGenie] -synonym: "upregulation of response to oxidative stress" EXACT [GOC:TermGenie] -is_a: GO:0048584 ! positive regulation of response to stimulus -is_a: GO:1902882 ! regulation of response to oxidative stress -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0006979 ! response to oxidative stress -relationship: positively_regulates GO:0006979 ! response to oxidative stress -created_by: kmv -creation_date: 2014-04-03T20:30:47Z - [Term] id: GO:1902902 name: negative regulation of autophagosome assembly @@ -137485,102 +121985,6 @@ relationship: positively_regulates GO:0060563 ! neuroepithelial cell differentia created_by: mr creation_date: 2014-04-18T21:06:42Z -[Term] -id: GO:1902930 -name: regulation of alcohol biosynthetic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of alcohol biosynthetic process." [GO_REF:0000058, GOC:mengo_curators, GOC:TermGenie, PMID:23332010] -synonym: "regulation of alcohol anabolism" EXACT [GOC:TermGenie] -synonym: "regulation of alcohol biosynthesis" EXACT [GOC:TermGenie] -synonym: "regulation of alcohol formation" EXACT [GOC:TermGenie] -synonym: "regulation of alcohol synthesis" EXACT [GOC:TermGenie] -synonym: "regulation of solventogenesis" BROAD [] -is_a: GO:0009889 ! regulation of biosynthetic process -is_a: GO:0062012 ! regulation of small molecule metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0046165 ! alcohol biosynthetic process -relationship: regulates GO:0046165 ! alcohol biosynthetic process -created_by: tt -creation_date: 2014-04-22T21:55:03Z - -[Term] -id: GO:1902931 -name: negative regulation of alcohol biosynthetic process -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process." [GO_REF:0000058, GOC:mengo_curators, GOC:TermGenie, PMID:23332010] -synonym: "down regulation of alcohol anabolism" EXACT [GOC:TermGenie] -synonym: "down regulation of alcohol biosynthesis" EXACT [GOC:TermGenie] -synonym: "down regulation of alcohol biosynthetic process" EXACT [GOC:TermGenie] -synonym: "down regulation of alcohol formation" EXACT [GOC:TermGenie] -synonym: "down regulation of alcohol synthesis" EXACT [GOC:TermGenie] -synonym: "down-regulation of alcohol anabolism" EXACT [GOC:TermGenie] -synonym: "down-regulation of alcohol biosynthesis" EXACT [GOC:TermGenie] -synonym: "down-regulation of alcohol biosynthetic process" EXACT [GOC:TermGenie] -synonym: "down-regulation of alcohol formation" EXACT [GOC:TermGenie] -synonym: "down-regulation of alcohol synthesis" EXACT [GOC:TermGenie] -synonym: "downregulation of alcohol anabolism" EXACT [GOC:TermGenie] -synonym: "downregulation of alcohol biosynthesis" EXACT [GOC:TermGenie] -synonym: "downregulation of alcohol biosynthetic process" EXACT [GOC:TermGenie] -synonym: "downregulation of alcohol formation" EXACT [GOC:TermGenie] -synonym: "downregulation of alcohol synthesis" EXACT [GOC:TermGenie] -synonym: "inhibition of alcohol anabolism" NARROW [GOC:TermGenie] -synonym: "inhibition of alcohol biosynthesis" NARROW [GOC:TermGenie] -synonym: "inhibition of alcohol biosynthetic process" NARROW [GOC:TermGenie] -synonym: "inhibition of alcohol formation" NARROW [GOC:TermGenie] -synonym: "inhibition of alcohol synthesis" NARROW [GOC:TermGenie] -synonym: "negative regulation of alcohol anabolism" EXACT [GOC:TermGenie] -synonym: "negative regulation of alcohol biosynthesis" EXACT [GOC:TermGenie] -synonym: "negative regulation of alcohol formation" EXACT [GOC:TermGenie] -synonym: "negative regulation of alcohol synthesis" EXACT [GOC:TermGenie] -synonym: "negative regulation of solventogenesis" BROAD [] -is_a: GO:0009890 ! negative regulation of biosynthetic process -is_a: GO:0062014 ! negative regulation of small molecule metabolic process -is_a: GO:1902930 ! regulation of alcohol biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0046165 ! alcohol biosynthetic process -relationship: negatively_regulates GO:0046165 ! alcohol biosynthetic process -created_by: tt -creation_date: 2014-04-22T21:55:13Z - -[Term] -id: GO:1902932 -name: positive regulation of alcohol biosynthetic process -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process." [GO_REF:0000058, GOC:mengo_curators, GOC:TermGenie, PMID:23332010] -synonym: "activation of alcohol anabolism" NARROW [GOC:TermGenie] -synonym: "activation of alcohol biosynthesis" NARROW [GOC:TermGenie] -synonym: "activation of alcohol biosynthetic process" NARROW [GOC:TermGenie] -synonym: "activation of alcohol formation" NARROW [GOC:TermGenie] -synonym: "activation of alcohol synthesis" NARROW [GOC:TermGenie] -synonym: "positive regulation of alcohol anabolism" EXACT [GOC:TermGenie] -synonym: "positive regulation of alcohol biosynthesis" EXACT [GOC:TermGenie] -synonym: "positive regulation of alcohol formation" EXACT [GOC:TermGenie] -synonym: "positive regulation of alcohol synthesis" EXACT [GOC:TermGenie] -synonym: "positive regulation of solventogenesis" BROAD [] -synonym: "up regulation of alcohol anabolism" EXACT [GOC:TermGenie] -synonym: "up regulation of alcohol biosynthesis" EXACT [GOC:TermGenie] -synonym: "up regulation of alcohol biosynthetic process" EXACT [GOC:TermGenie] -synonym: "up regulation of alcohol formation" EXACT [GOC:TermGenie] -synonym: "up regulation of alcohol synthesis" EXACT [GOC:TermGenie] -synonym: "up-regulation of alcohol anabolism" EXACT [GOC:TermGenie] -synonym: "up-regulation of alcohol biosynthesis" EXACT [GOC:TermGenie] -synonym: "up-regulation of alcohol biosynthetic process" EXACT [GOC:TermGenie] -synonym: "up-regulation of alcohol formation" EXACT [GOC:TermGenie] -synonym: "up-regulation of alcohol synthesis" EXACT [GOC:TermGenie] -synonym: "upregulation of alcohol anabolism" EXACT [GOC:TermGenie] -synonym: "upregulation of alcohol biosynthesis" EXACT [GOC:TermGenie] -synonym: "upregulation of alcohol biosynthetic process" EXACT [GOC:TermGenie] -synonym: "upregulation of alcohol formation" EXACT [GOC:TermGenie] -synonym: "upregulation of alcohol synthesis" EXACT [GOC:TermGenie] -is_a: GO:0009891 ! positive regulation of biosynthetic process -is_a: GO:0062013 ! positive regulation of small molecule metabolic process -is_a: GO:1902930 ! regulation of alcohol biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0046165 ! alcohol biosynthetic process -relationship: positively_regulates GO:0046165 ! alcohol biosynthetic process -created_by: tt -creation_date: 2014-04-22T21:55:19Z - [Term] id: GO:1903000 name: regulation of lipid transport across blood-brain barrier @@ -137704,8 +122108,7 @@ namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein synonym: "regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] -is_a: GO:0031323 ! regulation of cellular metabolic process -is_a: GO:0051246 ! regulation of protein metabolic process +is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009100 ! glycoprotein metabolic process relationship: regulates GO:0009100 ! glycoprotein metabolic process @@ -137727,8 +122130,7 @@ synonym: "downregulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "inhibition of glycoprotein metabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of glycoprotein metabolism" NARROW [GOC:TermGenie] synonym: "negative regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] -is_a: GO:0031324 ! negative regulation of cellular metabolic process -is_a: GO:0051248 ! negative regulation of protein metabolic process +is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:1903018 ! regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009100 ! glycoprotein metabolic process @@ -137751,8 +122153,7 @@ synonym: "up-regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "upregulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of glycoprotein metabolism" EXACT [GOC:TermGenie] -is_a: GO:0031325 ! positive regulation of cellular metabolic process -is_a: GO:0051247 ! positive regulation of protein metabolic process +is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:1903018 ! regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009100 ! glycoprotein metabolic process @@ -137987,6 +122388,7 @@ id: GO:1903048 name: regulation of acetylcholine-gated cation channel activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of acetylcholine-gated cation channel activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21718690] +is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity is_a: GO:0098815 ! modulation of excitatory postsynaptic potential is_a: GO:0098962 ! regulation of postsynaptic neurotransmitter receptor activity is_a: GO:2001257 ! regulation of cation channel activity @@ -138005,6 +122407,7 @@ synonym: "down regulation of acetylcholine-gated cation channel activity" EXACT synonym: "down-regulation of acetylcholine-gated cation channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine-gated cation channel activity" EXACT [GOC:TermGenie] synonym: "inhibition of acetylcholine-gated cation channel activity" NARROW [GOC:TermGenie] +is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity is_a: GO:1903048 ! regulation of acetylcholine-gated cation channel activity is_a: GO:2000272 ! negative regulation of signaling receptor activity is_a: GO:2001258 ! negative regulation of cation channel activity @@ -138461,8 +122864,8 @@ def: "Any process that modulates the frequency, rate or extent of calcium ion tr comment: human HRC regulates RYR2 and thus regulates transmembrane transport of calcium from SR to cytosol synonym: "regulation of calcium ion membrane transport" EXACT [GOC:TermGenie] synonym: "regulation of transmembrane calcium transport" EXACT [GOC:TermGenie] +is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0051924 ! regulation of calcium ion transport -is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070588 ! calcium ion transmembrane transport relationship: regulates GO:0070588 ! calcium ion transmembrane transport @@ -138489,9 +122892,9 @@ synonym: "inhibition of calcium ion transmembrane transport" NARROW [GOC:TermGen synonym: "inhibition of transmembrane calcium transport" NARROW [GOC:TermGenie] synonym: "negative regulation of calcium ion membrane transport" EXACT [GOC:TermGenie] synonym: "negative regulation of transmembrane calcium transport" EXACT [GOC:TermGenie] +is_a: GO:0034763 ! negative regulation of transmembrane transport is_a: GO:0051926 ! negative regulation of calcium ion transport is_a: GO:1903169 ! regulation of calcium ion transmembrane transport -is_a: GO:1904063 ! negative regulation of cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070588 ! calcium ion transmembrane transport relationship: negatively_regulates GO:0070588 ! calcium ion transmembrane transport @@ -139003,10 +123406,10 @@ id: GO:1903350 name: response to dopamine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:11118945] -is_a: GO:1901698 ! response to nitrogen compound +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:59905 ! dopaminium(1+) -relationship: has_input CHEBI:59905 ! dopaminium(1+) +intersection_of: has_input CHEBI:59905 +relationship: has_input CHEBI:59905 created_by: mr creation_date: 2014-08-19T19:33:26Z @@ -139015,10 +123418,10 @@ id: GO:1903351 name: cellular response to dopamine namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:11118945] -is_a: GO:1901699 ! cellular response to nitrogen compound +is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:1903350 ! response to dopamine intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:59905 ! dopaminium(1+) +intersection_of: has_input CHEBI:59905 created_by: mr creation_date: 2014-08-19T19:33:35Z @@ -139147,37 +123550,15 @@ relationship: positively_regulates GO:0007076 ! mitotic chromosome condensation created_by: al creation_date: 2014-08-26T13:57:29Z -[Term] -id: GO:1903409 -name: reactive oxygen species biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen." [GO_REF:0000068, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24252804] -synonym: "reactive oxygen species anabolism" EXACT [GOC:TermGenie] -synonym: "reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] -synonym: "reactive oxygen species formation" EXACT [GOC:TermGenie] -synonym: "reactive oxygen species generation" RELATED [PMID:24252804] -synonym: "reactive oxygen species synthesis" EXACT [GOC:TermGenie] -synonym: "ROS formation" RELATED [] -synonym: "ROS generation" RELATED [PMID:24252804] -is_a: GO:0009058 ! biosynthetic process -is_a: GO:0072593 ! reactive oxygen species metabolic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:26523 ! reactive oxygen species -relationship: has_primary_output CHEBI:26523 ! reactive oxygen species -created_by: bf -creation_date: 2014-09-03T09:19:13Z - [Term] id: GO:1903412 name: response to bile acid namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus." [GO_REF:0000071, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21757002] -is_a: GO:0014070 ! response to organic cyclic compound -is_a: GO:0033993 ! response to lipid -is_a: GO:1901700 ! response to oxygen-containing compound +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:3098 ! bile acid -relationship: has_input CHEBI:3098 ! bile acid +intersection_of: has_input CHEBI:3098 +relationship: has_input CHEBI:3098 created_by: rl creation_date: 2014-09-03T12:45:43Z @@ -139186,142 +123567,13 @@ id: GO:1903413 name: cellular response to bile acid namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus." [GO_REF:0000071, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21757002] -is_a: GO:0071396 ! cellular response to lipid -is_a: GO:0071407 ! cellular response to organic cyclic compound -is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:1903412 ! response to bile acid intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:3098 ! bile acid +intersection_of: has_input CHEBI:3098 created_by: rl creation_date: 2014-09-03T12:45:51Z -[Term] -id: GO:1903426 -name: regulation of reactive oxygen species biosynthetic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24252804] -synonym: "regulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] -synonym: "regulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] -synonym: "regulation of reactive oxygen species formation" EXACT [GOC:TermGenie] -synonym: "regulation of reactive oxygen species generation" RELATED [GOC:TermGenie] -synonym: "regulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] -synonym: "regulation of ROS formation" RELATED [GOC:TermGenie] -synonym: "regulation of ROS generation" RELATED [GOC:TermGenie] -is_a: GO:0009889 ! regulation of biosynthetic process -is_a: GO:2000377 ! regulation of reactive oxygen species metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:1903409 ! reactive oxygen species biosynthetic process -relationship: regulates GO:1903409 ! reactive oxygen species biosynthetic process -created_by: bf -creation_date: 2014-09-11T10:01:47Z - -[Term] -id: GO:1903427 -name: negative regulation of reactive oxygen species biosynthetic process -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24252804] -synonym: "down regulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] -synonym: "down regulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] -synonym: "down regulation of reactive oxygen species biosynthetic process" EXACT [GOC:TermGenie] -synonym: "down regulation of reactive oxygen species formation" EXACT [GOC:TermGenie] -synonym: "down regulation of reactive oxygen species generation" RELATED [GOC:TermGenie] -synonym: "down regulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] -synonym: "down regulation of ROS formation" RELATED [GOC:TermGenie] -synonym: "down regulation of ROS generation" RELATED [GOC:TermGenie] -synonym: "down-regulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] -synonym: "down-regulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] -synonym: "down-regulation of reactive oxygen species biosynthetic process" EXACT [GOC:TermGenie] -synonym: "down-regulation of reactive oxygen species formation" EXACT [GOC:TermGenie] -synonym: "down-regulation of reactive oxygen species generation" RELATED [GOC:TermGenie] -synonym: "down-regulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] -synonym: "down-regulation of ROS formation" RELATED [GOC:TermGenie] -synonym: "down-regulation of ROS generation" RELATED [GOC:TermGenie] -synonym: "downregulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] -synonym: "downregulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] -synonym: "downregulation of reactive oxygen species biosynthetic process" EXACT [GOC:TermGenie] -synonym: "downregulation of reactive oxygen species formation" EXACT [GOC:TermGenie] -synonym: "downregulation of reactive oxygen species generation" RELATED [GOC:TermGenie] -synonym: "downregulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] -synonym: "downregulation of ROS formation" RELATED [GOC:TermGenie] -synonym: "downregulation of ROS generation" RELATED [GOC:TermGenie] -synonym: "inhibition of reactive oxygen species anabolism" NARROW [GOC:TermGenie] -synonym: "inhibition of reactive oxygen species biosynthesis" NARROW [GOC:TermGenie] -synonym: "inhibition of reactive oxygen species biosynthetic process" NARROW [GOC:TermGenie] -synonym: "inhibition of reactive oxygen species formation" NARROW [GOC:TermGenie] -synonym: "inhibition of reactive oxygen species generation" RELATED [GOC:TermGenie] -synonym: "inhibition of reactive oxygen species synthesis" NARROW [GOC:TermGenie] -synonym: "inhibition of ROS formation" RELATED [GOC:TermGenie] -synonym: "inhibition of ROS generation" RELATED [GOC:TermGenie] -synonym: "negative regulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] -synonym: "negative regulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] -synonym: "negative regulation of reactive oxygen species formation" EXACT [GOC:TermGenie] -synonym: "negative regulation of reactive oxygen species generation" RELATED [GOC:TermGenie] -synonym: "negative regulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] -synonym: "negative regulation of ROS formation" RELATED [GOC:TermGenie] -synonym: "negative regulation of ROS generation" RELATED [GOC:TermGenie] -synonym: "prevention of ROS generation" EXACT [PMID:24252804] -is_a: GO:0009890 ! negative regulation of biosynthetic process -is_a: GO:1903426 ! regulation of reactive oxygen species biosynthetic process -is_a: GO:2000378 ! negative regulation of reactive oxygen species metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:1903409 ! reactive oxygen species biosynthetic process -relationship: negatively_regulates GO:1903409 ! reactive oxygen species biosynthetic process -created_by: bf -creation_date: 2014-09-11T10:01:56Z - -[Term] -id: GO:1903428 -name: positive regulation of reactive oxygen species biosynthetic process -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24252804] -synonym: "activation of reactive oxygen species anabolism" NARROW [GOC:TermGenie] -synonym: "activation of reactive oxygen species biosynthesis" NARROW [GOC:TermGenie] -synonym: "activation of reactive oxygen species biosynthetic process" NARROW [GOC:TermGenie] -synonym: "activation of reactive oxygen species formation" NARROW [GOC:TermGenie] -synonym: "activation of reactive oxygen species generation" RELATED [GOC:TermGenie] -synonym: "activation of reactive oxygen species synthesis" NARROW [GOC:TermGenie] -synonym: "activation of ROS formation" RELATED [GOC:TermGenie] -synonym: "activation of ROS generation" RELATED [GOC:TermGenie] -synonym: "positive regulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] -synonym: "positive regulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] -synonym: "positive regulation of reactive oxygen species formation" EXACT [GOC:TermGenie] -synonym: "positive regulation of reactive oxygen species generation" RELATED [GOC:TermGenie] -synonym: "positive regulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] -synonym: "positive regulation of ROS formation" RELATED [GOC:TermGenie] -synonym: "positive regulation of ROS generation" RELATED [GOC:TermGenie] -synonym: "up regulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] -synonym: "up regulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] -synonym: "up regulation of reactive oxygen species biosynthetic process" EXACT [GOC:TermGenie] -synonym: "up regulation of reactive oxygen species formation" EXACT [GOC:TermGenie] -synonym: "up regulation of reactive oxygen species generation" RELATED [GOC:TermGenie] -synonym: "up regulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] -synonym: "up regulation of ROS formation" RELATED [GOC:TermGenie] -synonym: "up regulation of ROS generation" RELATED [GOC:TermGenie] -synonym: "up-regulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] -synonym: "up-regulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] -synonym: "up-regulation of reactive oxygen species biosynthetic process" EXACT [GOC:TermGenie] -synonym: "up-regulation of reactive oxygen species formation" EXACT [GOC:TermGenie] -synonym: "up-regulation of reactive oxygen species generation" RELATED [GOC:TermGenie] -synonym: "up-regulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] -synonym: "up-regulation of ROS formation" RELATED [GOC:TermGenie] -synonym: "up-regulation of ROS generation" RELATED [GOC:TermGenie] -synonym: "upregulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] -synonym: "upregulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] -synonym: "upregulation of reactive oxygen species biosynthetic process" EXACT [GOC:TermGenie] -synonym: "upregulation of reactive oxygen species formation" EXACT [GOC:TermGenie] -synonym: "upregulation of reactive oxygen species generation" RELATED [GOC:TermGenie] -synonym: "upregulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] -synonym: "upregulation of ROS formation" RELATED [GOC:TermGenie] -synonym: "upregulation of ROS generation" RELATED [GOC:TermGenie] -is_a: GO:0009891 ! positive regulation of biosynthetic process -is_a: GO:1903426 ! regulation of reactive oxygen species biosynthetic process -is_a: GO:2000379 ! positive regulation of reactive oxygen species metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:1903409 ! reactive oxygen species biosynthetic process -relationship: positively_regulates GO:1903409 ! reactive oxygen species biosynthetic process -created_by: bf -creation_date: 2014-09-11T10:02:05Z - [Term] id: GO:1903429 name: regulation of cell maturation @@ -139500,30 +123752,16 @@ relationship: capable_of GO:0042030 ! ATPase inhibitor activity created_by: bhm creation_date: 2014-09-30T13:55:37Z -[Term] -id: GO:1903509 -name: liposaccharide metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving liposaccharide." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:9452964] -synonym: "liposaccharide metabolism" EXACT [GOC:TermGenie] -is_a: GO:0006629 ! lipid metabolic process -is_a: GO:1901135 ! carbohydrate derivative metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:35740 ! liposaccharide -relationship: has_primary_input_or_output CHEBI:35740 ! liposaccharide -created_by: dph -creation_date: 2014-10-01T21:52:52Z - [Term] id: GO:1903510 name: mucopolysaccharide metabolic process namespace: biological_process def: "The chemical reactions and pathways involving mucopolysaccharide." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:4236091] synonym: "mucopolysaccharide metabolism" EXACT [GOC:TermGenie] -is_a: GO:0030203 ! glycosaminoglycan metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:37395 ! mucopolysaccharide -relationship: has_primary_input_or_output CHEBI:37395 ! mucopolysaccharide +intersection_of: has_primary_input_or_output CHEBI:37395 +relationship: has_primary_input_or_output CHEBI:37395 created_by: dph creation_date: 2014-10-01T21:55:47Z @@ -139795,30 +124033,6 @@ relationship: positively_regulates GO:1990182 ! exosomal secretion created_by: pga creation_date: 2014-10-14T11:39:10Z -[Term] -id: GO:1903544 -name: response to butyrate -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:9734870] -is_a: GO:0070542 ! response to fatty acid -intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:17968 ! butyrate -relationship: has_input CHEBI:17968 ! butyrate -created_by: mr -creation_date: 2014-10-17T13:57:25Z - -[Term] -id: GO:1903545 -name: cellular response to butyrate -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:9734870] -is_a: GO:0071398 ! cellular response to fatty acid -is_a: GO:1903544 ! response to butyrate -intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:17968 ! butyrate -created_by: mr -creation_date: 2014-10-17T13:57:35Z - [Term] id: GO:1903551 name: regulation of extracellular exosome assembly @@ -140194,7 +124408,7 @@ def: "Any process that modulates the frequency, rate or extent of DNA catabolic synonym: "regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "regulation of DNA degradation" EXACT [GOC:TermGenie] -is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006308 ! DNA catabolic process @@ -140226,7 +124440,7 @@ synonym: "inhibition of DNA degradation" NARROW [GOC:TermGenie] synonym: "negative regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of DNA degradation" EXACT [GOC:TermGenie] -is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0051053 ! negative regulation of DNA metabolic process is_a: GO:1903624 ! regulation of DNA catabolic process intersection_of: GO:0065007 ! biological regulation @@ -140259,7 +124473,7 @@ synonym: "upregulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of DNA degradation" EXACT [GOC:TermGenie] -is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0051054 ! positive regulation of DNA metabolic process is_a: GO:1903624 ! regulation of DNA catabolic process intersection_of: GO:0065007 ! biological regulation @@ -140653,74 +124867,6 @@ relationship: regulates GO:0003333 ! amino acid transmembrane transport created_by: al creation_date: 2015-01-08T17:42:18Z -[Term] -id: GO:1903795 -name: regulation of inorganic anion transmembrane transport -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802] -synonym: "regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] -synonym: "regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] -is_a: GO:0034762 ! regulation of transmembrane transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0098661 ! inorganic anion transmembrane transport -relationship: regulates GO:0098661 ! inorganic anion transmembrane transport -created_by: sl -creation_date: 2015-01-14T21:44:49Z - -[Term] -id: GO:1903796 -name: negative regulation of inorganic anion transmembrane transport -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802] -synonym: "down regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] -synonym: "down regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] -synonym: "down regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] -synonym: "down-regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] -synonym: "down-regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] -synonym: "down-regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] -synonym: "downregulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] -synonym: "downregulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] -synonym: "downregulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] -synonym: "inhibition of inorganic anion membrane transport" NARROW [GOC:TermGenie] -synonym: "inhibition of inorganic anion transmembrane transport" NARROW [GOC:TermGenie] -synonym: "inhibition of transmembrane inorganic anion transport" NARROW [GOC:TermGenie] -synonym: "negative regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] -synonym: "negative regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] -is_a: GO:0034763 ! negative regulation of transmembrane transport -is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0098661 ! inorganic anion transmembrane transport -relationship: negatively_regulates GO:0098661 ! inorganic anion transmembrane transport -created_by: sl -creation_date: 2015-01-14T21:44:59Z - -[Term] -id: GO:1903797 -name: positive regulation of inorganic anion transmembrane transport -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802] -synonym: "activation of inorganic anion membrane transport" NARROW [GOC:TermGenie] -synonym: "activation of inorganic anion transmembrane transport" NARROW [GOC:TermGenie] -synonym: "activation of transmembrane inorganic anion transport" NARROW [GOC:TermGenie] -synonym: "positive regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] -synonym: "positive regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] -synonym: "up regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] -synonym: "up regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] -synonym: "up regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] -synonym: "up-regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] -synonym: "up-regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] -synonym: "up-regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] -synonym: "upregulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] -synonym: "upregulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] -synonym: "upregulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] -is_a: GO:0034764 ! positive regulation of transmembrane transport -is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0098661 ! inorganic anion transmembrane transport -relationship: positively_regulates GO:0098661 ! inorganic anion transmembrane transport -created_by: sl -creation_date: 2015-01-14T21:45:08Z - [Term] id: GO:1903825 name: organic acid transmembrane transport @@ -140729,7 +124875,7 @@ def: "The process in which an organic acid is transported across a membrane." [G is_a: GO:0015849 ! organic acid transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:64709 ! organic acid +intersection_of: has_primary_input CHEBI:64709 intersection_of: results_in_transport_across GO:0016020 ! membrane created_by: vw creation_date: 2015-01-20T10:20:58Z @@ -140971,10 +125117,10 @@ id: GO:1903924 name: estradiol binding namespace: molecular_function def: "Binding to estradiol." [GO_REF:0000067, GOC:TermGenie, PMID:9048584] -is_a: GO:0005496 ! steroid binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:23965 ! estradiol -relationship: has_input CHEBI:23965 ! estradiol +intersection_of: has_input CHEBI:23965 +relationship: has_input CHEBI:23965 created_by: sl creation_date: 2015-02-11T00:11:34Z @@ -141362,10 +125508,10 @@ id: GO:1904014 name: response to serotonin namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:1505525] -is_a: GO:1901698 ! response to nitrogen compound +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:350546 ! serotonin(1+) -relationship: has_input CHEBI:350546 ! serotonin(1+) +intersection_of: has_input CHEBI:350546 +relationship: has_input CHEBI:350546 created_by: sl creation_date: 2015-03-06T19:33:54Z @@ -141374,10 +125520,10 @@ id: GO:1904015 name: cellular response to serotonin namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:1505525] -is_a: GO:1901699 ! cellular response to nitrogen compound +is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:1904014 ! response to serotonin intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:350546 ! serotonin(1+) +intersection_of: has_input CHEBI:350546 created_by: sl creation_date: 2015-03-06T19:34:00Z @@ -141576,12 +125722,10 @@ id: GO:1904044 name: response to aldosterone namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:17644563] -is_a: GO:0051385 ! response to mineralocorticoid -is_a: GO:0097305 ! response to alcohol -is_a: GO:1901654 ! response to ketone +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:27584 ! aldosterone -relationship: has_input CHEBI:27584 ! aldosterone +intersection_of: has_input CHEBI:27584 +relationship: has_input CHEBI:27584 created_by: sl creation_date: 2015-03-16T23:07:53Z @@ -141590,13 +125734,10 @@ id: GO:1904045 name: cellular response to aldosterone namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:17644563] -is_a: GO:0071389 ! cellular response to mineralocorticoid stimulus -is_a: GO:0097306 ! cellular response to alcohol -is_a: GO:0110096 ! cellular response to aldehyde -is_a: GO:1901655 ! cellular response to ketone +is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:1904044 ! response to aldosterone intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:27584 ! aldosterone +intersection_of: has_input CHEBI:27584 created_by: sl creation_date: 2015-03-16T23:07:59Z @@ -141717,7 +125858,7 @@ name: regulation of monoatomic cation transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482] synonym: "regulation of cation transmembrane transport" BROAD [] -is_a: GO:0034765 ! regulation of monoatomic ion transmembrane transport +is_a: GO:0034762 ! regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0098655 ! monoatomic cation transmembrane transport relationship: regulates GO:0098655 ! monoatomic cation transmembrane transport @@ -141733,7 +125874,7 @@ synonym: "down regulation of cation transmembrane transport" EXACT [GOC:TermGeni synonym: "down-regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "inhibition of cation transmembrane transport" NARROW [GOC:TermGenie] -is_a: GO:0034766 ! negative regulation of monoatomic ion transmembrane transport +is_a: GO:0034763 ! negative regulation of transmembrane transport is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0098655 ! monoatomic cation transmembrane transport @@ -141750,7 +125891,7 @@ synonym: "activation of cation transmembrane transport" NARROW [GOC:TermGenie] synonym: "up regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of cation transmembrane transport" EXACT [GOC:TermGenie] -is_a: GO:0034767 ! positive regulation of monoatomic ion transmembrane transport +is_a: GO:0034764 ! positive regulation of transmembrane transport is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0098655 ! monoatomic cation transmembrane transport @@ -141964,10 +126105,10 @@ id: GO:1904116 name: response to vasopressin namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22811487] -is_a: GO:0043434 ! response to peptide hormone +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:9937 ! vasopressin -relationship: has_input CHEBI:9937 ! vasopressin +intersection_of: has_input CHEBI:9937 +relationship: has_input CHEBI:9937 created_by: sl creation_date: 2015-04-06T19:39:42Z @@ -141976,10 +126117,10 @@ id: GO:1904117 name: cellular response to vasopressin namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22811487] -is_a: GO:0071375 ! cellular response to peptide hormone stimulus +is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:1904116 ! response to vasopressin intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:9937 ! vasopressin +intersection_of: has_input CHEBI:9937 created_by: sl creation_date: 2015-04-06T19:39:48Z @@ -142621,7 +126762,7 @@ def: "Any process that modulates the frequency, rate or extent of an iron transm synonym: "regulation of iron cation channel activity" EXACT [GOC:TermGenie] synonym: "regulation of iron channel activity" EXACT [] synonym: "regulation of iron-specific channel activity" EXACT [GOC:TermGenie] -is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity +is_a: GO:0022898 ! regulation of transmembrane transporter activity is_a: GO:0034759 ! regulation of iron ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005381 ! iron ion transmembrane transporter activity @@ -142649,7 +126790,7 @@ synonym: "inhibition of iron-specific channel activity" NARROW [GOC:TermGenie] synonym: "negative regulation of iron cation channel activity" EXACT [GOC:TermGenie] synonym: "negative regulation of iron channel activity" EXACT [] synonym: "negative regulation of iron-specific channel activity" EXACT [GOC:TermGenie] -is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity +is_a: GO:0032410 ! negative regulation of transporter activity is_a: GO:0034760 ! negative regulation of iron ion transmembrane transport is_a: GO:1904254 ! regulation of iron ion transmembrane transporter activity intersection_of: GO:0065007 ! biological regulation @@ -142679,7 +126820,7 @@ synonym: "up-regulation of iron-specific channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of iron cation channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of iron channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of iron-specific channel activity" EXACT [GOC:TermGenie] -is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity +is_a: GO:0032411 ! positive regulation of transporter activity is_a: GO:0034761 ! positive regulation of iron ion transmembrane transport is_a: GO:1904254 ! regulation of iron ion transmembrane transporter activity intersection_of: GO:0065007 ! biological regulation @@ -143386,7 +127527,7 @@ synonym: "downregulation of nitric oxide metabolism" EXACT [GOC:TermGenie] synonym: "inhibition of nitric oxide metabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of nitric oxide metabolism" NARROW [GOC:TermGenie] synonym: "negative regulation of nitric oxide metabolism" EXACT [GOC:TermGenie] -is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0080164 ! regulation of nitric oxide metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046209 ! nitric oxide metabolic process @@ -143408,7 +127549,7 @@ synonym: "up-regulation of nitric oxide metabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of nitric oxide metabolism" EXACT [GOC:TermGenie] synonym: "upregulation of nitric oxide metabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of nitric oxide metabolism" EXACT [GOC:TermGenie] -is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0080164 ! regulation of nitric oxide metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046209 ! nitric oxide metabolic process @@ -143421,12 +127562,10 @@ id: GO:1904408 name: melatonin binding namespace: molecular_function def: "Binding to melatonin." [GO_REF:0000067, GOC:mr, GOC:TermGenie, PMID:10379923] -is_a: GO:0033218 ! amide binding -is_a: GO:0097159 ! organic cyclic compound binding -is_a: GO:1901363 ! heterocyclic compound binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:16796 ! melatonin -relationship: has_input CHEBI:16796 ! melatonin +intersection_of: has_input CHEBI:16796 +relationship: has_input CHEBI:16796 created_by: mr creation_date: 2015-06-25T19:19:53Z @@ -143565,9 +127704,9 @@ synonym: "up-regulation of transmembrane calcium transport" EXACT [GOC:TermGenie synonym: "upregulation of calcium ion membrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of calcium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of transmembrane calcium transport" EXACT [GOC:TermGenie] +is_a: GO:0034764 ! positive regulation of transmembrane transport is_a: GO:0051928 ! positive regulation of calcium ion transport is_a: GO:1903169 ! regulation of calcium ion transmembrane transport -is_a: GO:1904064 ! positive regulation of cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070588 ! calcium ion transmembrane transport relationship: positively_regulates GO:0070588 ! calcium ion transmembrane transport @@ -143815,11 +127954,10 @@ name: response to glycoprotein namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:14597422] synonym: "response to glycoproteins" EXACT [] -is_a: GO:0010243 ! response to organonitrogen compound -is_a: GO:1901700 ! response to oxygen-containing compound +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:17089 ! glycoprotein -relationship: has_input CHEBI:17089 ! glycoprotein +intersection_of: has_input CHEBI:17089 +relationship: has_input CHEBI:17089 created_by: sl creation_date: 2015-08-20T16:46:24Z @@ -143829,11 +127967,10 @@ name: cellular response to glycoprotein namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:14597422] synonym: "cellular response to glycoproteins" EXACT [] -is_a: GO:0071417 ! cellular response to organonitrogen compound -is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:1904587 ! response to glycoprotein intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:17089 ! glycoprotein +intersection_of: has_input CHEBI:17089 created_by: sl creation_date: 2015-08-20T16:46:30Z @@ -144210,11 +128347,11 @@ namespace: biological_process alt_id: GO:0015758 def: "The process in which glucose is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:9090050] synonym: "glucose transport" RELATED [] -is_a: GO:0008645 ! hexose transmembrane transport +is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:17234 ! glucose +intersection_of: has_primary_input CHEBI:17234 intersection_of: results_in_transport_across GO:0016020 ! membrane -relationship: has_primary_input CHEBI:17234 ! glucose +relationship: has_primary_input CHEBI:17234 created_by: vw creation_date: 2015-09-04T17:20:16Z @@ -144352,11 +128489,11 @@ def: "Enables the transfer of a peptide from one side of a membrane to the other synonym: "peptide transporter activity" RELATED [] synonym: "peptide uptake permease activity" RELATED [] xref: Reactome:R-HSA-1500817 "Glutathione is taken up by the bacterium" -is_a: GO:0042887 ! amide transmembrane transporter activity +is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0005215 ! transporter activity -intersection_of: has_primary_input CHEBI:16670 ! peptide +intersection_of: has_primary_input CHEBI:16670 intersection_of: results_in_transport_across GO:0016020 ! membrane -relationship: has_primary_input CHEBI:16670 ! peptide +relationship: has_primary_input CHEBI:16670 created_by: tb creation_date: 2015-09-22T18:50:41Z @@ -146257,20 +130394,6 @@ relationship: results_in_organization_of GO:0005776 ! autophagosome created_by: bf creation_date: 2016-03-08T14:18:10Z -[Term] -id: GO:1905038 -name: regulation of membrane lipid metabolic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of membrane lipid metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:25954280] -synonym: "regulation of membrane lipid metabolism" EXACT [GOC:TermGenie] -is_a: GO:0019216 ! regulation of lipid metabolic process -is_a: GO:0031323 ! regulation of cellular metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0006643 ! membrane lipid metabolic process -relationship: regulates GO:0006643 ! membrane lipid metabolic process -created_by: tb -creation_date: 2016-03-08T20:41:32Z - [Term] id: GO:1905039 name: carboxylic acid transmembrane transport @@ -146279,7 +130402,7 @@ def: "The process in which carboxylic acid is transported across a membrane." [G is_a: GO:0046942 ! carboxylic acid transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:29067 ! carboxylic acid anion +intersection_of: has_primary_input CHEBI:29067 intersection_of: results_in_transport_across GO:0016020 ! membrane created_by: vw creation_date: 2016-03-09T15:33:53Z @@ -146743,12 +130866,10 @@ id: GO:1905144 name: response to acetylcholine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21238497] -is_a: GO:0010033 ! response to organic substance -is_a: GO:1901698 ! response to nitrogen compound -is_a: GO:1901700 ! response to oxygen-containing compound +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:15355 ! acetylcholine -relationship: has_input CHEBI:15355 ! acetylcholine +intersection_of: has_input CHEBI:15355 +relationship: has_input CHEBI:15355 created_by: dos creation_date: 2016-04-14T08:54:49Z @@ -146757,11 +130878,10 @@ id: GO:1905145 name: cellular response to acetylcholine namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21238497] -is_a: GO:1901699 ! cellular response to nitrogen compound -is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:1905144 ! response to acetylcholine intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:15355 ! acetylcholine +intersection_of: has_input CHEBI:15355 created_by: dos creation_date: 2016-04-14T08:54:58Z @@ -147254,6 +131374,19 @@ relationship: results_in_morphogenesis_of UBERON:0002348 ! epicardium created_by: rl creation_date: 2016-06-07T10:02:32Z +[Term] +id: GO:1905232 +name: cellular response to L-glutamate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:25962137] +synonym: "cellular response to L-glutamate(1-)" RELATED [] +is_a: GO:0070887 ! cellular response to chemical stimulus +is_a: GO:1902065 ! response to L-glutamate +intersection_of: GO:0070887 ! cellular response to chemical stimulus +intersection_of: has_input CHEBI:29985 +created_by: sl +creation_date: 2016-06-07T17:30:08Z + [Term] id: GO:1905268 name: negative regulation of chromatin organization @@ -148313,10 +132446,10 @@ synonym: "response to aminoacetic acid" EXACT [] synonym: "response to aminoethanoic acid" EXACT [] synonym: "response to Gly" EXACT [] synonym: "response to glycin" EXACT [] -is_a: GO:0010033 ! response to organic substance +is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_input CHEBI:57305 ! glycine zwitterion -relationship: has_input CHEBI:57305 ! glycine zwitterion +intersection_of: has_input CHEBI:57305 +relationship: has_input CHEBI:57305 created_by: sl creation_date: 2016-09-08T22:09:15Z @@ -148332,7 +132465,7 @@ synonym: "cellular response to glycin" EXACT [] is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:1905429 ! response to glycine intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_input CHEBI:57305 ! glycine zwitterion +intersection_of: has_input CHEBI:57305 created_by: sl creation_date: 2016-09-08T22:09:23Z @@ -150783,55 +134916,6 @@ relationship: positively_regulates GO:0061154 ! endothelial tube morphogenesis created_by: rph creation_date: 2017-02-21T15:17:39Z -[Term] -id: GO:1905957 -name: regulation of cellular response to alcohol -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of cellular response to alcohol." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] -is_a: GO:0050794 ! regulation of cellular process -is_a: GO:1901419 ! regulation of response to alcohol -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0097306 ! cellular response to alcohol -relationship: regulates GO:0097306 ! cellular response to alcohol -created_by: hbye -creation_date: 2017-02-22T12:03:00Z - -[Term] -id: GO:1905958 -name: negative regulation of cellular response to alcohol -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] -synonym: "down regulation of cellular response to alcohol" EXACT [GOC:TermGenie] -synonym: "down-regulation of cellular response to alcohol" EXACT [GOC:TermGenie] -synonym: "downregulation of cellular response to alcohol" EXACT [GOC:TermGenie] -synonym: "inhibition of cellular response to alcohol" NARROW [GOC:TermGenie] -is_a: GO:0048523 ! negative regulation of cellular process -is_a: GO:1901420 ! negative regulation of response to alcohol -is_a: GO:1905957 ! regulation of cellular response to alcohol -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0097306 ! cellular response to alcohol -relationship: negatively_regulates GO:0097306 ! cellular response to alcohol -created_by: hbye -creation_date: 2017-02-22T12:03:08Z - -[Term] -id: GO:1905959 -name: positive regulation of cellular response to alcohol -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of cellular response to alcohol." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] -synonym: "activation of cellular response to alcohol" NARROW [GOC:TermGenie] -synonym: "up regulation of cellular response to alcohol" EXACT [GOC:TermGenie] -synonym: "up-regulation of cellular response to alcohol" EXACT [GOC:TermGenie] -synonym: "upregulation of cellular response to alcohol" EXACT [GOC:TermGenie] -is_a: GO:0048522 ! positive regulation of cellular process -is_a: GO:1901421 ! positive regulation of response to alcohol -is_a: GO:1905957 ! regulation of cellular response to alcohol -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0097306 ! cellular response to alcohol -relationship: positively_regulates GO:0097306 ! cellular response to alcohol -created_by: hbye -creation_date: 2017-02-22T12:03:16Z - [Term] id: GO:1905962 name: glutamatergic neuron differentiation @@ -150934,8 +135018,8 @@ def: "Binding to a steroid hormone." [GOC:ln] is_a: GO:0005496 ! steroid binding is_a: GO:0042562 ! hormone binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:26764 ! steroid hormone -relationship: has_input CHEBI:26764 ! steroid hormone +intersection_of: has_input CHEBI:26764 +relationship: has_input CHEBI:26764 created_by: pr creation_date: 2013-11-15T09:26:18Z @@ -151037,7 +135121,7 @@ synonym: "lipid transport across blood brain barrier" EXACT [] is_a: GO:0006869 ! lipid transport is_a: GO:0150104 ! transport across blood-brain barrier intersection_of: GO:0150104 ! transport across blood-brain barrier -intersection_of: has_primary_input CHEBI:18059 ! lipid +intersection_of: has_primary_input CHEBI:18059 intersection_of: results_in_transport_across UBERON:0000120 ! blood brain barrier relationship: in_taxon NCBITaxon:6072 {all_only="true"} ! Eumetazoa created_by: sjp @@ -151048,10 +135132,10 @@ id: GO:1990461 name: detoxification of iron ion namespace: biological_process def: "Any process that reduces or removes the toxicity of iron ion. These include transport of iron away from sensitive areas and to compartments or complexes whose purpose is sequestration of iron ion." [GOC:sart, PMID:23064556] -is_a: GO:0061687 ! detoxification of inorganic compound +is_a: GO:0098754 ! detoxification intersection_of: GO:0098754 ! detoxification -intersection_of: has_input CHEBI:24875 ! iron cation -relationship: has_input CHEBI:24875 ! iron cation +intersection_of: has_input CHEBI:24875 +relationship: has_input CHEBI:24875 relationship: part_of GO:0010039 ! response to iron ion created_by: sart creation_date: 2014-08-19T10:12:46Z @@ -151208,6 +135292,18 @@ relationship: has_part GO:0015276 ! ligand-gated monoatomic ion channel activity created_by: bhm creation_date: 2015-07-20T12:09:56Z +[Term] +id: GO:1990822 +name: basic amino acid transmembrane transport +namespace: biological_process +def: "The directed movement of basic amino acids from one side of a membrane to the other." [GOC:dph, GOC:vw] +is_a: GO:0003333 ! amino acid transmembrane transport +is_a: GO:0015802 ! basic amino acid transport +intersection_of: GO:0015802 ! basic amino acid transport +intersection_of: results_in_transport_across GO:0016020 ! membrane +created_by: vw +creation_date: 2015-08-19T07:47:00Z + [Term] id: GO:1990845 name: adaptive thermogenesis @@ -151277,7 +135373,7 @@ synonym: "RNA-protein complex" EXACT [] synonym: "RNP" EXACT [] xref: Wikipedia:Ribonucleoprotein is_a: GO:0032991 ! protein-containing complex -relationship: has_part CHEBI:33697 ! ribonucleic acid +relationship: has_part CHEBI:33697 created_by: pr creation_date: 2015-11-19T12:26:37Z @@ -151800,43 +135896,6 @@ relationship: positively_regulates GO:0071888 ! macrophage apoptotic process created_by: mah creation_date: 2010-09-15T01:44:21Z -[Term] -id: GO:2000112 -name: regulation of cellular macromolecule biosynthetic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process." [GOC:obol] -synonym: "regulation of cellular biopolymer biosynthetic process" EXACT [GOC:obol] -synonym: "regulation of cellular macromolecule anabolism" EXACT [GOC:obol] -synonym: "regulation of cellular macromolecule biosynthesis" EXACT [GOC:obol] -synonym: "regulation of cellular macromolecule formation" EXACT [GOC:obol] -synonym: "regulation of cellular macromolecule synthesis" EXACT [GOC:obol] -is_a: GO:0010556 ! regulation of macromolecule biosynthetic process -is_a: GO:0031326 ! regulation of cellular biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0034645 ! cellular macromolecule biosynthetic process -relationship: regulates GO:0034645 ! cellular macromolecule biosynthetic process -created_by: tb -creation_date: 2010-09-15T08:55:45Z - -[Term] -id: GO:2000113 -name: negative regulation of cellular macromolecule biosynthetic process -namespace: biological_process -def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cellular macromolecule biosynthetic process." [GOC:obol] -synonym: "negative regulation of cellular biopolymer biosynthetic process" EXACT [GOC:obol] -synonym: "negative regulation of cellular macromolecule anabolism" EXACT [GOC:obol] -synonym: "negative regulation of cellular macromolecule biosynthesis" EXACT [GOC:obol] -synonym: "negative regulation of cellular macromolecule formation" EXACT [GOC:obol] -synonym: "negative regulation of cellular macromolecule synthesis" EXACT [GOC:obol] -is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process -is_a: GO:0031327 ! negative regulation of cellular biosynthetic process -is_a: GO:2000112 ! regulation of cellular macromolecule biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0034645 ! cellular macromolecule biosynthetic process -relationship: negatively_regulates GO:0034645 ! cellular macromolecule biosynthetic process -created_by: tb -creation_date: 2010-09-15T08:55:48Z - [Term] id: GO:2000114 name: regulation of establishment of cell polarity @@ -152097,9 +136156,7 @@ synonym: "regulation of progesterone anabolism" EXACT [GOC:obol] synonym: "regulation of progesterone biosynthesis" EXACT [GOC:obol] synonym: "regulation of progesterone formation" EXACT [GOC:obol] synonym: "regulation of progesterone synthesis" EXACT [GOC:obol] -is_a: GO:0010566 ! regulation of ketone biosynthetic process -is_a: GO:0046885 ! regulation of hormone biosynthetic process -is_a: GO:0050810 ! regulation of steroid biosynthetic process +is_a: GO:0009889 ! regulation of biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006701 ! progesterone biosynthetic process relationship: regulates GO:0006701 ! progesterone biosynthetic process @@ -152115,9 +136172,7 @@ synonym: "negative regulation of progesterone anabolism" EXACT [GOC:obol] synonym: "negative regulation of progesterone biosynthesis" EXACT [GOC:obol] synonym: "negative regulation of progesterone formation" EXACT [GOC:obol] synonym: "negative regulation of progesterone synthesis" EXACT [GOC:obol] -is_a: GO:0010894 ! negative regulation of steroid biosynthetic process -is_a: GO:0032353 ! negative regulation of hormone biosynthetic process -is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:2000182 ! regulation of progesterone biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006701 ! progesterone biosynthetic process @@ -152134,9 +136189,7 @@ synonym: "positive regulation of progesterone anabolism" EXACT [GOC:obol] synonym: "positive regulation of progesterone biosynthesis" EXACT [GOC:obol] synonym: "positive regulation of progesterone formation" EXACT [GOC:obol] synonym: "positive regulation of progesterone synthesis" EXACT [GOC:obol] -is_a: GO:0010893 ! positive regulation of steroid biosynthetic process -is_a: GO:0046886 ! positive regulation of hormone biosynthetic process -is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:2000182 ! regulation of progesterone biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006701 ! progesterone biosynthetic process @@ -152144,86 +136197,6 @@ relationship: positively_regulates GO:0006701 ! progesterone biosynthetic proces created_by: dph creation_date: 2010-10-14T07:36:14Z -[Term] -id: GO:2000185 -name: regulation of phosphate transmembrane transport -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol] -synonym: "regulation of phosphate membrane transport" EXACT [] -is_a: GO:0010966 ! regulation of phosphate transport -is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0035435 ! phosphate ion transmembrane transport -relationship: regulates GO:0035435 ! phosphate ion transmembrane transport -created_by: vw -creation_date: 2010-10-15T11:33:04Z - -[Term] -id: GO:2000186 -name: negative regulation of phosphate transmembrane transport -namespace: biological_process -def: "Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol] -synonym: "negative regulation of phosphate membrane transport" EXACT [] -is_a: GO:1903796 ! negative regulation of inorganic anion transmembrane transport -is_a: GO:2000185 ! regulation of phosphate transmembrane transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0035435 ! phosphate ion transmembrane transport -relationship: negatively_regulates GO:0035435 ! phosphate ion transmembrane transport -created_by: vw -creation_date: 2010-10-15T11:33:08Z - -[Term] -id: GO:2000187 -name: positive regulation of phosphate transmembrane transport -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol] -synonym: "positive regulation of phosphate membrane transport" EXACT [] -is_a: GO:1903797 ! positive regulation of inorganic anion transmembrane transport -is_a: GO:2000185 ! regulation of phosphate transmembrane transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0035435 ! phosphate ion transmembrane transport -relationship: positively_regulates GO:0035435 ! phosphate ion transmembrane transport -created_by: vw -creation_date: 2010-10-15T11:33:10Z - -[Term] -id: GO:2000191 -name: regulation of fatty acid transport -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of fatty acid transport." [GOC:BHF] -is_a: GO:0032368 ! regulation of lipid transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0015908 ! fatty acid transport -relationship: regulates GO:0015908 ! fatty acid transport -created_by: rl -creation_date: 2010-10-18T10:37:13Z - -[Term] -id: GO:2000192 -name: negative regulation of fatty acid transport -namespace: biological_process -def: "Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport." [GOC:BHF] -is_a: GO:0032369 ! negative regulation of lipid transport -is_a: GO:2000191 ! regulation of fatty acid transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0015908 ! fatty acid transport -relationship: negatively_regulates GO:0015908 ! fatty acid transport -created_by: rl -creation_date: 2010-10-18T10:37:15Z - -[Term] -id: GO:2000193 -name: positive regulation of fatty acid transport -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of fatty acid transport." [GOC:BHF] -is_a: GO:0032370 ! positive regulation of lipid transport -is_a: GO:2000191 ! regulation of fatty acid transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0015908 ! fatty acid transport -relationship: positively_regulates GO:0015908 ! fatty acid transport -created_by: rl -creation_date: 2010-10-18T10:37:17Z - [Term] id: GO:2000194 name: regulation of female gonad development @@ -152321,8 +136294,7 @@ id: GO:2000224 name: regulation of testosterone biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of testosterone biosynthetic process." [GOC:obol, GOC:yaf] -is_a: GO:0010566 ! regulation of ketone biosynthetic process -is_a: GO:0050810 ! regulation of steroid biosynthetic process +is_a: GO:0009889 ! regulation of biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061370 ! testosterone biosynthetic process relationship: regulates GO:0061370 ! testosterone biosynthetic process @@ -152334,9 +136306,7 @@ id: GO:2000225 name: negative regulation of testosterone biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of testosterone biosynthetic process." [GOC:obol, GOC:yaf] -is_a: GO:0010894 ! negative regulation of steroid biosynthetic process -is_a: GO:0031327 ! negative regulation of cellular biosynthetic process -is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:2000224 ! regulation of testosterone biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061370 ! testosterone biosynthetic process @@ -152595,8 +136565,7 @@ synonym: "regulation of DNA anabolism" EXACT [GOC:obol] synonym: "regulation of DNA biosynthesis" EXACT [GOC:obol] synonym: "regulation of DNA formation" EXACT [GOC:obol] synonym: "regulation of DNA synthesis" EXACT [GOC:obol] -is_a: GO:0010556 ! regulation of macromolecule biosynthetic process -is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0071897 ! DNA biosynthetic process @@ -152613,8 +136582,7 @@ synonym: "negative regulation of DNA anabolism" EXACT [GOC:obol] synonym: "negative regulation of DNA biosynthesis" EXACT [GOC:obol] synonym: "negative regulation of DNA formation" EXACT [GOC:obol] synonym: "negative regulation of DNA synthesis" EXACT [GOC:obol] -is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process -is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0051053 ! negative regulation of DNA metabolic process is_a: GO:2000278 ! regulation of DNA biosynthetic process intersection_of: GO:0065007 ! biological regulation @@ -152634,7 +136602,7 @@ synonym: "regulation of cellular amino acid biosynthesis" EXACT [GOC:obol] synonym: "regulation of cellular amino acid formation" EXACT [GOC:obol] synonym: "regulation of cellular amino acid synthesis" EXACT [GOC:obol] is_a: GO:0006521 ! regulation of cellular amino acid metabolic process -is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0009889 ! regulation of biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008652 ! amino acid biosynthetic process relationship: regulates GO:0008652 ! amino acid biosynthetic process @@ -152651,7 +136619,7 @@ synonym: "negative regulation of amino acid biosynthesis" EXACT [GOC:obol] synonym: "negative regulation of amino acid formation" EXACT [GOC:obol] synonym: "negative regulation of amino acid synthesis" EXACT [GOC:obol] synonym: "negative regulation of cellular amino acid biosynthetic process" EXACT [GOC:obol] -is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0045763 ! negative regulation of cellular amino acid metabolic process is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process intersection_of: GO:0065007 ! biological regulation @@ -152670,7 +136638,7 @@ synonym: "positive regulation of amino acid biosynthesis" EXACT [GOC:obol] synonym: "positive regulation of amino acid formation" EXACT [GOC:obol] synonym: "positive regulation of amino acid synthesis" EXACT [GOC:obol] synonym: "positive regulation of cellular amino acid biosynthetic process" EXACT [GOC:obol] -is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0045764 ! positive regulation of amino acid metabolic process is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process intersection_of: GO:0065007 ! biological regulation @@ -153083,50 +137051,6 @@ relationship: positively_regulates GO:0072592 ! oxygen metabolic process created_by: mah creation_date: 2011-02-11T02:03:52Z -[Term] -id: GO:2000377 -name: regulation of reactive oxygen species metabolic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process." [GOC:mah] -synonym: "regulation of reactive oxygen species metabolism" EXACT [GOC:obol] -synonym: "regulation of ROS metabolic process" EXACT [GOC:obol] -is_a: GO:0031323 ! regulation of cellular metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0072593 ! reactive oxygen species metabolic process -relationship: regulates GO:0072593 ! reactive oxygen species metabolic process -created_by: mah -creation_date: 2011-02-11T02:06:36Z - -[Term] -id: GO:2000378 -name: negative regulation of reactive oxygen species metabolic process -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process." [GOC:mah] -synonym: "negative regulation of reactive oxygen species metabolism" EXACT [GOC:obol] -synonym: "negative regulation of ROS metabolic process" EXACT [GOC:obol] -is_a: GO:0031324 ! negative regulation of cellular metabolic process -is_a: GO:2000377 ! regulation of reactive oxygen species metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0072593 ! reactive oxygen species metabolic process -relationship: negatively_regulates GO:0072593 ! reactive oxygen species metabolic process -created_by: mah -creation_date: 2011-02-11T02:06:49Z - -[Term] -id: GO:2000379 -name: positive regulation of reactive oxygen species metabolic process -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process." [GOC:mah] -synonym: "positive regulation of reactive oxygen species metabolism" EXACT [GOC:obol] -synonym: "positive regulation of ROS metabolic process" EXACT [GOC:obol] -is_a: GO:0031325 ! positive regulation of cellular metabolic process -is_a: GO:2000377 ! regulation of reactive oxygen species metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0072593 ! reactive oxygen species metabolic process -relationship: positively_regulates GO:0072593 ! reactive oxygen species metabolic process -created_by: mah -creation_date: 2011-02-11T02:06:57Z - [Term] id: GO:2000380 name: regulation of mesoderm development @@ -154310,8 +138234,7 @@ synonym: "positive regulation of DNA anabolism" EXACT [GOC:obol] synonym: "positive regulation of DNA biosynthesis" EXACT [GOC:obol] synonym: "positive regulation of DNA formation" EXACT [GOC:obol] synonym: "positive regulation of DNA synthesis" EXACT [GOC:obol] -is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process -is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0051054 ! positive regulation of DNA metabolic process is_a: GO:2000278 ! regulation of DNA biosynthetic process intersection_of: GO:0065007 ! biological regulation @@ -154516,50 +138439,6 @@ relationship: positively_regulates GO:0072089 ! stem cell proliferation created_by: dph creation_date: 2011-04-27T01:04:25Z -[Term] -id: GO:2000649 -name: regulation of sodium ion transmembrane transporter activity -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] -synonym: "regulation of sodium transporter activity" EXACT [GOC:obol] -is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity -is_a: GO:1902305 ! regulation of sodium ion transmembrane transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0015081 ! sodium ion transmembrane transporter activity -relationship: regulates GO:0015081 ! sodium ion transmembrane transporter activity -created_by: yaf -creation_date: 2011-04-28T08:42:53Z - -[Term] -id: GO:2000650 -name: negative regulation of sodium ion transmembrane transporter activity -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] -synonym: "negative regulation of sodium transporter activity" EXACT [GOC:obol] -is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity -is_a: GO:1902306 ! negative regulation of sodium ion transmembrane transport -is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0015081 ! sodium ion transmembrane transporter activity -relationship: negatively_regulates GO:0015081 ! sodium ion transmembrane transporter activity -created_by: yaf -creation_date: 2011-04-28T08:42:57Z - -[Term] -id: GO:2000651 -name: positive regulation of sodium ion transmembrane transporter activity -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] -synonym: "positive regulation of sodium transporter activity" EXACT [GOC:obol] -is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity -is_a: GO:1902307 ! positive regulation of sodium ion transmembrane transport -is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0015081 ! sodium ion transmembrane transporter activity -relationship: positively_regulates GO:0015081 ! sodium ion transmembrane transporter activity -created_by: yaf -creation_date: 2011-04-28T08:43:00Z - [Term] id: GO:2000654 name: regulation of cellular response to testosterone stimulus @@ -154587,44 +138466,6 @@ relationship: negatively_regulates GO:0071394 ! cellular response to testosteron created_by: vk creation_date: 2011-05-02T03:23:59Z -[Term] -id: GO:2000656 -name: regulation of apolipoprotein binding -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of apolipoprotein binding." [GOC:BHF] -is_a: GO:0043393 ! regulation of protein binding -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0034185 ! apolipoprotein binding -relationship: regulates GO:0034185 ! apolipoprotein binding -created_by: vk -creation_date: 2011-05-02T05:33:41Z - -[Term] -id: GO:2000657 -name: negative regulation of apolipoprotein binding -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein binding." [GOC:BHF] -is_a: GO:0032091 ! negative regulation of protein binding -is_a: GO:2000656 ! regulation of apolipoprotein binding -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0034185 ! apolipoprotein binding -relationship: negatively_regulates GO:0034185 ! apolipoprotein binding -created_by: vk -creation_date: 2011-05-02T05:33:44Z - -[Term] -id: GO:2000658 -name: positive regulation of apolipoprotein binding -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of apolipoprotein binding." [GOC:BHF] -is_a: GO:0032092 ! positive regulation of protein binding -is_a: GO:2000656 ! regulation of apolipoprotein binding -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0034185 ! apolipoprotein binding -relationship: positively_regulates GO:0034185 ! apolipoprotein binding -created_by: vk -creation_date: 2011-05-02T05:33:46Z - [Term] id: GO:2000668 name: regulation of dendritic cell apoptotic process @@ -155327,7 +139168,6 @@ id: GO:2000843 name: regulation of testosterone secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of testosterone secretion." [GOC:sl] -is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0046883 ! regulation of hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035936 ! testosterone secretion @@ -155340,7 +139180,6 @@ id: GO:2000844 name: negative regulation of testosterone secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion." [GOC:sl] -is_a: GO:0032369 ! negative regulation of lipid transport is_a: GO:0046888 ! negative regulation of hormone secretion is_a: GO:2000843 ! regulation of testosterone secretion intersection_of: GO:0065007 ! biological regulation @@ -155354,7 +139193,6 @@ id: GO:2000845 name: positive regulation of testosterone secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of testosterone secretion." [GOC:sl] -is_a: GO:0032370 ! positive regulation of lipid transport is_a: GO:0046887 ! positive regulation of hormone secretion is_a: GO:2000843 ! regulation of testosterone secretion intersection_of: GO:0065007 ! biological regulation @@ -155518,47 +139356,6 @@ relationship: positively_regulates GO:0035932 ! aldosterone secretion created_by: bf creation_date: 2011-07-26T08:47:34Z -[Term] -id: GO:2000861 -name: regulation of estrogen secretion -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of estrogen secretion." [GOC:sl] -synonym: "regulation of oestrogen secretion" RELATED [GOC:obol] -is_a: GO:2000831 ! regulation of steroid hormone secretion -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0035937 ! estrogen secretion -relationship: regulates GO:0035937 ! estrogen secretion -created_by: bf -creation_date: 2011-07-26T08:48:24Z - -[Term] -id: GO:2000862 -name: negative regulation of estrogen secretion -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of estrogen secretion." [GOC:sl] -synonym: "negative regulation of oestrogen secretion" RELATED [GOC:obol] -is_a: GO:2000832 ! negative regulation of steroid hormone secretion -is_a: GO:2000861 ! regulation of estrogen secretion -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0035937 ! estrogen secretion -relationship: negatively_regulates GO:0035937 ! estrogen secretion -created_by: bf -creation_date: 2011-07-26T08:48:28Z - -[Term] -id: GO:2000863 -name: positive regulation of estrogen secretion -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of estrogen secretion." [GOC:sl] -synonym: "positive regulation of oestrogen secretion" RELATED [GOC:obol] -is_a: GO:2000833 ! positive regulation of steroid hormone secretion -is_a: GO:2000861 ! regulation of estrogen secretion -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0035937 ! estrogen secretion -relationship: positively_regulates GO:0035937 ! estrogen secretion -created_by: bf -creation_date: 2011-07-26T08:48:31Z - [Term] id: GO:2000864 name: regulation of estradiol secretion @@ -156034,21 +139831,6 @@ relationship: positively_regulates GO:0097152 ! mesenchymal cell apoptotic proce created_by: yaf creation_date: 2011-09-08T02:50:09Z -[Term] -id: GO:2001057 -name: reactive nitrogen species metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving a reactive nitrogen species." [GOC:obol] -synonym: "reactive nitrogen species metabolism" EXACT [GOC:obol] -synonym: "RNS metabolic process" EXACT [GOC:obol] -synonym: "RNS metabolism" EXACT [GOC:obol] -is_a: GO:0006807 ! nitrogen compound metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:62764 ! reactive nitrogen species -relationship: has_primary_input_or_output CHEBI:62764 ! reactive nitrogen species -created_by: jl -creation_date: 2011-09-09T01:29:13Z - [Term] id: GO:2001069 name: glycogen binding @@ -156056,10 +139838,10 @@ namespace: molecular_function def: "Binding to glycogen." [GOC:mengo_curators] synonym: "animal starch binding" RELATED [GOC:obol] synonym: "liver starch binding" RELATED [GOC:obol] -is_a: GO:0030247 ! polysaccharide binding +is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_input CHEBI:28087 ! glycogen -relationship: has_input CHEBI:28087 ! glycogen +intersection_of: has_input CHEBI:28087 +relationship: has_input CHEBI:28087 created_by: jl creation_date: 2011-09-14T12:01:06Z @@ -156072,8 +139854,7 @@ synonym: "regulation of RNA anabolism" EXACT [GOC:obol] synonym: "regulation of RNA biosynthesis" EXACT [GOC:obol] synonym: "regulation of RNA formation" EXACT [GOC:obol] synonym: "regulation of RNA synthesis" EXACT [GOC:obol] -is_a: GO:0010556 ! regulation of macromolecule biosynthetic process -is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0051252 ! regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032774 ! RNA biosynthetic process @@ -156471,7 +140252,7 @@ namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cation channel activity." [GOC:BHF] synonym: "regulation of cation diffusion facilitator activity" EXACT [GOC:obol] synonym: "regulation of nonselective cation channel activity" EXACT [GOC:obol] -is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity +is_a: GO:0022898 ! regulation of transmembrane transporter activity is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005261 ! monoatomic cation channel activity @@ -156486,7 +140267,7 @@ namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cation channel activity." [GOC:BHF] synonym: "negative regulation of cation diffusion facilitator activity" EXACT [GOC:obol] synonym: "negative regulation of nonselective cation channel activity" EXACT [GOC:obol] -is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity +is_a: GO:0032410 ! negative regulation of transporter activity is_a: GO:1904063 ! negative regulation of cation transmembrane transport is_a: GO:2001257 ! regulation of cation channel activity intersection_of: GO:0065007 ! biological regulation @@ -156502,7 +140283,7 @@ namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cation channel activity." [GOC:BHF] synonym: "positive regulation of cation diffusion facilitator activity" EXACT [GOC:obol] synonym: "positive regulation of nonselective cation channel activity" EXACT [GOC:obol] -is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity +is_a: GO:0032411 ! positive regulation of transporter activity is_a: GO:1904064 ! positive regulation of cation transmembrane transport is_a: GO:2001257 ! regulation of cation channel activity intersection_of: GO:0065007 ! biological regulation @@ -159911,7 +143692,7 @@ def: "An amino acid chain that is produced de novo by ribosome-mediated translat comment: The definition above excludes protein complexes, which some also consider a protein. Those who wish to refer to a class representing both senses of the word are directed to CHEBI:36080. Note that the definition allows for experimentally-manipulated genes, and allows for artifically-produced derivatives that mimic those found naturally. Proteins (in the sense defined here) that descended from a common ancestor can be classified into families and superfamilies composed of products of evolutionarily-related genes. The domain architecture of a protein is described by the order of its constituent domains. Proteins with the same domains in the same order are defined as homeomorphic [PRO:WCB]. synonym: "native protein" NARROW [IEDB:BP] synonym: "natural protein" EXACT [PRO:DAN] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 [Term] id: PR:000000680 @@ -159964,7 +143745,7 @@ synonym: "differentiation antigen CD19" EXACT [] synonym: "T-cell surface antigen Leu-12" EXACT [] xref: IUPHARobj:2764 xref: PIRSF:PIRSF016630 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -159976,7 +143757,7 @@ comment: Category=gene. Requested by=CL. synonym: "CD34" EXACT PRO-short-label [PRO:DNx] synonym: "hematopoietic progenitor cell antigen CD34" EXACT [] xref: PIRSF:PIRSF028749 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -159990,7 +143771,7 @@ synonym: "T-cell differentiation antigen L3T4" EXACT [] synonym: "T-cell surface antigen T4/Leu-3" EXACT [] synonym: "T-cell surface glycoprotein CD4" EXACT [] xref: PIRSF:PIRSF001977 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160018,7 +143799,7 @@ synonym: "PTPRC" EXACT PRO-short-label [PRO:DNx] synonym: "T200" BROAD [PRO:DNx] xref: IUPHARobj:1852 xref: PIRSF:PIRSF002004 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160129,7 +143910,7 @@ def: "A protein that has a core domain composition consisting of an extracellula comment: Category=family. synonym: "CD3 subunit with Ig-like domain" EXACT [] xref: PIRSF:PIRSF001993 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160152,7 +143933,7 @@ namespace: protein def: "A protein with a domain composition consisting of a large extracellular domain, including five Ig-like C2-type domains followed by two copies of the Fibronectin type-III domain (Pfam:PF00041), a single-pass transmembrane domain and a short cytoplasmic C-terminal domain." [PRO:CNA] comment: Category=family. xref: PIRSF:PIRSF002507 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160185,7 +143966,7 @@ namespace: protein def: "A protein that is a type I transmembrane receptor with an N-terminal cysteine-rich domain, a single Fibronectin type II (FNII) domain (Pfam:PF00040) and eight to ten copies of the Lectin C-type domain (Pfam:PF00059) (CTLDs). The presence of multiple copies of the CTLD domain is a hallmark of this class." [PMID:12223280] comment: Category=family. xref: PIRSF:PIRSF002427 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160222,7 +144003,7 @@ synonym: "T-cell surface antigen T11/Leu-5" EXACT [] synonym: "T-cell surface glycoprotein CD2" EXACT [] xref: IUPHARobj:2600 xref: PIRSF:PIRSF001984 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160238,7 +144019,7 @@ synonym: "Lyt2" RELATED Gene-based [] synonym: "MAL" RELATED Gene-based [] synonym: "T-cell surface glycoprotein Lyt-2" EXACT [] synonym: "T-lymphocyte differentiation antigen T8/Leu-2" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160256,7 +144037,7 @@ synonym: "Lyt3" RELATED Gene-based [] synonym: "T-cell membrane glycoprotein Ly-3" EXACT [] synonym: "T-cell surface glycoprotein Lyt-3" EXACT [] xref: PIRSF:PIRSF002020 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160704,7 +144485,7 @@ namespace: protein def: "A protein that contains the ADP-ribosyl cyclase domain (Pfam:PF02267)." [PRO:WCB] comment: Category=family. xref: PIRSF:PIRSF005736 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160722,7 +144503,7 @@ synonym: "siglec-2" EXACT [] synonym: "SIGLEC2" RELATED Gene-based [] synonym: "T-cell surface antigen Leu-14" EXACT [] xref: IUPHARobj:2786 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160744,7 +144525,7 @@ synonym: "MS4A1" EXACT PRO-short-label [PRO:DNx] synonym: "Ms4a2" RELATED Gene-based [] xref: IUPHARobj:2628 xref: PIRSF:PIRSF001995 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160753,7 +144534,7 @@ name: B7-related protein namespace: protein def: "A protein that is a member of a family that includes translation products of genes CD86, CD276, ICOSLG, and others. These are membrane-anchored proteins with a small intracellular domain and an extracellular domain with signal sequence, an Immunoglobulin V-set domain (Pfam:PF07686), and a CD80-like C2-set immunoglobulin domain (Pfam:PF08205)." [PRO:WCB] comment: Category=family. -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160774,7 +144555,7 @@ synonym: "dendritic lectin" EXACT [] synonym: "DLEC" RELATED Gene-based [] synonym: "HECL" RELATED Gene-based [] synonym: "UNQ9361/PRO34150" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160786,7 +144567,7 @@ comment: Category=gene. Requested by=CL. synonym: "CD207" EXACT PRO-short-label [PRO:DNx] synonym: "CLEC4K" RELATED Gene-based [] synonym: "langerin" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160803,7 +144584,7 @@ synonym: "DC-SIGN" RELATED [] synonym: "DC-SIGN1" EXACT [] synonym: "dendritic cell-specific ICAM-3-grabbing non-integrin 1" EXACT [] xref: IUPHARobj:2930 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160833,7 +144614,7 @@ synonym: "PGP-1" EXACT [] synonym: "PGP-I" RELATED [] synonym: "phagocytic glycoprotein 1" EXACT [] synonym: "phagocytic glycoprotein I" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160859,7 +144640,7 @@ synonym: "SLAM family member 2" EXACT [] synonym: "SLAMF2" EXACT [] synonym: "TCT.1" EXACT [] xref: PIRSF:PIRSF001973 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160872,7 +144653,7 @@ synonym: "B-cell activation protein" EXACT [] synonym: "CD83" EXACT PRO-short-label [PRO:DNx] synonym: "CD83 antigen" EXACT [] synonym: "cell surface protein HB15" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160899,7 +144680,7 @@ synonym: "lymphocyte surface MEL-14 antigen" EXACT [] synonym: "SELL" EXACT PRO-short-label [PRO:DNx] synonym: "TQ1" EXACT [] xref: PIRSF:PIRSF002421 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160914,7 +144695,7 @@ synonym: "hly9-beta" EXACT [] synonym: "leukocyte differentiation antigen CD84" EXACT [] synonym: "signaling lymphocytic activation molecule 5" EXACT [] synonym: "SLAMF5" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160924,7 +144705,7 @@ namespace: protein def: "A protein that is a stand alone version of the Glycosyltransferase family 10 (fucosyltransferase) (Pfam:PF00852) domain. Proteins in this class may catalyze alpha-1,3 glycosidic linkages." [PMID:9451017] comment: Category=family. xref: PIRSF:PIRSF005726 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160939,7 +144720,7 @@ synonym: "CD317" EXACT [] synonym: "HM1.24 antigen" EXACT [] synonym: "tetherin" EXACT [] xref: PIRSF:PIRSF023920 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160949,7 +144730,7 @@ namespace: protein def: "A protein that has a core domain structure of signal sequence, propeptide, five Cadherin domains (Pfam:PF00028), a transmembrane region, and a Cadherin cytoplasmic region (Pfam:PF01049). Cadherins function as adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in solid tissues." [PRO:WCB] comment: Category=family. xref: PIRSF:PIRSF002504 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160964,7 +144745,7 @@ synonym: "CD67 antigen" EXACT [] synonym: "CEACAM8" EXACT PRO-short-label [PRO:DNx] synonym: "CGM6" RELATED Gene-based [] synonym: "non-specific cross-reacting antigen NCA-95" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160977,7 +144758,7 @@ synonym: "C3b/C4b receptor" EXACT [] synonym: "C3BR" RELATED Gene-based [] synonym: "CD35" EXACT [] synonym: "CR1" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -160994,7 +144775,7 @@ synonym: "Cr2" EXACT [] synonym: "EBV receptor" EXACT [] synonym: "epstein-Barr virus receptor" EXACT [] xref: PIRSF:PIRSF002484 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161015,7 +144796,7 @@ synonym: "early T-cell activation antigen p60" EXACT [] synonym: "GP32/28" EXACT [] synonym: "leukocyte surface antigen Leu-23" EXACT [] synonym: "MLR-3" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161032,7 +144813,7 @@ synonym: "PD-Ibeta" EXACT [] synonym: "PDNP3" RELATED Gene-based [] synonym: "phosphodiesterase I beta" EXACT [] synonym: "phosphodiesterase I/nucleotide pyrophosphatase 3" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161048,7 +144829,7 @@ synonym: "END" RELATED Gene-based [] synonym: "ENG" EXACT PRO-short-label [PRO:DNx] xref: IUPHARobj:2895 xref: PIRSF:PIRSF038746 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161061,7 +144842,7 @@ synonym: "FOXP3" EXACT PRO-short-label [PRO:DNx] synonym: "IPEX" RELATED Gene-based [] synonym: "JM2" RELATED Gene-based [] synonym: "scurfin" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161071,7 +144852,7 @@ namespace: protein def: "A protein that contains an extracellular Glycophorin A domain (Pfam:PF01102), followed by a single-pass transmembrane region and a small intracellular domain. A protein that is an integral protein of the red cell membrane. Proteins in this class are responsible for the molecular basis of the blood group antigens, surface markers on the outside of the red blood cell membrane." [InterPro:IPR001195, PRO:CNA] comment: Category=family. xref: PIRSF:PIRSF002466 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161081,7 +144862,7 @@ namespace: protein def: "A protein with a core domain architecture consisting of an extracellular domain containing two copies of the Immunoglobulin domain (Pfam:PF00047), followed by a single-pass transmembrane region and a small intracellular domain. The active protein is a low affinity receptor for immunoglobulin gamma chain Fc region. Human II-a, II-b, and II-c represent a recent gene expansion and are equally related to mouse II, III, and IV. Human III-A and III-B are closely related and closer to mouse IV than to mouse III." [PRO:WCB] comment: Category=family. xref: PIRSF:PIRSF001980 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161092,7 +144873,7 @@ def: "A protein with a core domain architecture consisting of an extracellular d comment: Category=family. Note: The active protein is a low affinity receptor for immunoglobulin gamma chain Fc region. It comprises the translation products of the FCGR1 gene (mouse) or one of the closely related FCGR1A, FCGR1B, or FCGR1C genes (human). FCGR1C may be a pseudogene in human. synonym: "Fc-gamma receptor" RELATED [] xref: PIRSF:PIRSF001981 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161112,7 +144893,7 @@ synonym: "p55" BROAD [PRO:DNx] synonym: "TAC antigen" EXACT [] xref: IUPHARobj:1695 xref: PIRSF:PIRSF001954 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161131,7 +144912,7 @@ synonym: "IL2RB" EXACT PRO-short-label [PRO:DNx] synonym: "p70-75" EXACT [] synonym: "p75" BROAD [PRO:DNx] xref: IUPHARobj:1696 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161160,7 +144941,7 @@ synonym: "KLRD1" EXACT PRO-short-label [PRO:DNx] synonym: "KP43" EXACT [] synonym: "natural killer cells antigen CD94" EXACT [] synonym: "NK cell receptor" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161170,7 +144951,7 @@ namespace: protein def: "A protein with four transmembrane domains, small intracellular amino- and carboxyl-terminal regions, and two extracellular loops, a small one (EC1) and a larger one (EC2) of about 100 residues. The EC2 loop contains at least 4 cysteine residues, including a highly conserved 'CCG' motif." [PRO:WCB, Wikipedia:Tetraspanin] comment: Category=family. xref: PIRSF:PIRSF002419 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161441,7 +145222,7 @@ def: "A protein that has a core domain composition consisting of a Rel homology comment: Category=family. synonym: "transcription factor NF-kappa-B" RELATED [] xref: PIRSF:PIRSF036310 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161452,7 +145233,7 @@ def: "A protein with core architecture consisting of one Prominin (Pfam:PF05478) comment: Category=family. xref: PANTHER:PTHR22730 xref: PIRSF:PIRSF017831 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161486,7 +145267,7 @@ synonym: "dectin-2" EXACT [] synonym: "DECTIN2" RELATED Gene-based [] synonym: "dendritic cell-associated C-type lectin 2" EXACT [] xref: IUPHARobj:2928 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161507,7 +145288,7 @@ synonym: "DECTIN1" RELATED Gene-based [] synonym: "dendritic cell-associated C-type lectin 1" EXACT [] synonym: "UNQ539/PRO1082" RELATED Gene-based [] xref: IUPHARobj:2927 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161518,7 +145299,7 @@ def: "A protein that is a translation product of the human CD59 gene, a 1:1 orth comment: Category=gene. Requested by=CL. Pro-orthology refers to, in this case, after-speciation gene duplication in the non-human species (aka 1:many orthology). This gene is present as a single copy in human and has undergone a lineage-specific duplication in mouse. CD59 antigen has a core architecture consisting of one UPAR/Ly-6 domain (Pfam:PF00021), a small domain of about 70 amino acids and containing 5 conserved disulfide bonds. It is both N- and O-glycosylated and is a GPI-anchored protein that releases soluble forms in some tissues. synonym: "CD59-like" EXACT PRO-short-label [PRO:DNx] xref: PIRSF:PIRSF038782 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161528,7 +145309,7 @@ namespace: protein def: "A protein with core architecture consisting of asignal sequence, 5 Ig-like domains, followed by a transmembrane sequence, followed by a Protein tyrosine kinase domain (Pfam:PF07714). However, only 1-3 of the Ig domains are detected by the Pfam HMMs in most of the sequences. Pfam:PF00047 is most common, but other members of the Ig domain clan, Pfam:PF07679 and Pfam:PF07686 can be identified instead. The fourth Ig domain lacks the disulfide-bonded cysteines." [PRO:WCB] comment: Category=family. xref: PIRSF:PIRSF000615 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161556,7 +145337,7 @@ namespace: protein def: "A protein with core architecture consisting of a signal sequence, a Class II histocompatibility antigen, alpha domain (Pfam:PF00993) and an Immunoglobulin C1-set domain (Pfam:PF07654); these form the extracellular domain and are followed by a single-pass transmembrane region and a small cytoplasmic region." [PRO:WCB, Wikipedia:Human_leukocyte_antigen] comment: Category=family. Note: There are three major and two minor class II MHC (major histocompatability complex) alpha chain genes in human. Designations for the MHC complex loci are species specific: HLA (human leukocyte antigen) in human, H-2 in mouse. MHC class II loci are characterized by large numbers of allelic variants. In contrast to MHC Class I alpha chain genes, orthologies can be seen between some human and mouse genes. MHC class II alpha chains form heterodimers with MHLC class II beta chains. synonym: "MHCcIIalpha" EXACT PRO-short-label [PRO:DAN] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161566,7 +145347,7 @@ namespace: protein def: "A protein with core architecture consisting of a signal sequence, one Immunoglobulin V-set domain (Pfam:PF07686), two Immunoglobulin C1-set domains (Pfam:PF07654), a single-pass transmembrane region and a very small cytoplasmic region." [PRO:WCB] comment: Category=family. xref: PIRSF:PIRSF038063 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161580,7 +145361,7 @@ synonym: "CDw150" EXACT [] synonym: "IPO-3" EXACT [] synonym: "SLAM" RELATED Gene-based [] synonym: "SLAMF1" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161595,7 +145376,7 @@ synonym: "TBET" RELATED Gene-based [] synonym: "TBLYM" RELATED Gene-based [] synonym: "TBX21" EXACT PRO-short-label [PRO:DNx] synonym: "transcription factor TBLYM" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161611,7 +145392,7 @@ synonym: "T-cell leukemia antigen" EXACT [] synonym: "T-cell surface antigen Leu-9" EXACT [] synonym: "TP41" EXACT [] xref: PIRSF:PIRSF038791 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161622,7 +145403,7 @@ def: "A protein with core architecture consisting of a signal sequence, an extra comment: Category=family. synonym: "CD1" EXACT PRO-short-label [PRO:DAN] xref: PIRSF:PIRSF038798 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161637,7 +145418,7 @@ synonym: "ly-1" EXACT [] synonym: "lymphocyte antigen 1" EXACT [] synonym: "lymphocyte antigen T1/Leu-1" EXACT [] synonym: "Lyt-1" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161649,7 +145430,7 @@ comment: Category=gene. Requested by=CL. synonym: "CD28" EXACT PRO-short-label [PRO:DNx] synonym: "TP44" EXACT [] xref: IUPHARobj:2863 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161664,7 +145445,7 @@ synonym: "Thy-1" RELATED Gene-based [] synonym: "Thy-1 antigen" EXACT [] synonym: "THY1" EXACT PRO-short-label [PRO:DNx] xref: PIRSF:PIRSF038777 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161677,7 +145458,7 @@ synonym: "ARG1" EXACT PRO-short-label [PRO:DNx] synonym: "liver-type arginase" EXACT [] synonym: "type I arginase" EXACT [] xref: IUPHARobj:1244 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161706,7 +145487,7 @@ synonym: "CTLA-4" EXACT [] synonym: "CTLA4" EXACT PRO-short-label [PRO:DNx] synonym: "cytotoxic T-lymphocyte-associated antigen 4" EXACT [] xref: IUPHARobj:2743 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161723,7 +145504,7 @@ synonym: "VPREB" RELATED Gene-based [] synonym: "VpreB protein" EXACT [] synonym: "VPREB1" EXACT PRO-short-label [PRO:DNx] xref: PIRSF:PIRSF038787 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161740,7 +145521,7 @@ synonym: "IGL1" RELATED Gene-based [] synonym: "IGLL1" EXACT PRO-short-label [PRO:DNx] synonym: "immunoglobulin omega polypeptide" EXACT [] synonym: "immunoglobulin-related protein 14.1" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161758,7 +145539,7 @@ synonym: "CD28-related protein 1" EXACT [] synonym: "CRP-1" RELATED [] synonym: "ICOS" EXACT PRO-short-label [PRO:DNx] xref: IUPHARobj:2939 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161768,7 +145549,7 @@ namespace: protein def: "A protein with core architecture consisting of a large extracellular region containing one Integrin, beta chain domain (Pfam:PF00362), up to four EGF-like domains (Pfam:PF07974), and an Integrin beta tail domain (Pfam:PF07965), followed by a single-pass transmembrane region and a small cytoplasmic region often containing an Integrin beta cytoplasmic domain (Pfam:PF08725)." [PRO:WCB] comment: Category=family. xref: PIRSF:PIRSF002512 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161787,7 +145568,7 @@ synonym: "IL3RA" EXACT PRO-short-label [PRO:DNx] synonym: "interleukin-3 receptor class II alpha chain" EXACT [] synonym: "Sut-1" RELATED Gene-based [] xref: IUPHARobj:1705 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161806,7 +145587,7 @@ synonym: "IL5R" RELATED Gene-based [] synonym: "IL5RA" EXACT PRO-short-label [PRO:DNx] xref: IUPHARobj:1706 xref: PIRSF:PIRSF018419 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161824,7 +145605,7 @@ synonym: "IL-7RA" EXACT [] synonym: "IL7R" EXACT PRO-short-label [PRO:DNx] xref: IUPHARobj:1698 xref: PIRSF:PIRSF001960 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161834,7 +145615,7 @@ namespace: protein def: "A protein that is a translation product of the KLRB1 gene or its closely related paralogs (KLRB1A-F). There are lineage-specific expansions in mouse and rat." [PRO:WCB] comment: Category=family. Requested by=CL. xref: PIRSF:PIRSF038804 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161853,7 +145634,7 @@ synonym: "lymphocyte antigen 48" EXACT [] synonym: "sialophorin" EXACT [] synonym: "SPN" EXACT PRO-short-label [PRO:DNx] xref: PIRSF:PIRSF001994 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161876,7 +145657,7 @@ synonym: "immunoglobulin E-binding factor" EXACT [] synonym: "lymphocyte IgE receptor" EXACT [] xref: IUPHARobj:2935 xref: PIRSF:PIRSF002426 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161886,7 +145667,7 @@ namespace: protein def: "A protein with core architecture consisting of a Lysosome-associated membrane glycoprotein (Pfam:PF01299) domain. It is a single-pass type I membrane protein that shuttles between lysosomes, endosomes, and the plasma membrane." [PRO:WCB] comment: Category=family. xref: PIRSF:PIRSF002462 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161899,7 +145680,7 @@ synonym: "macrophage receptor with collagenous structure" EXACT [] synonym: "MARCO" EXACT PRO-short-label [PRO:DNx] synonym: "SCARA2" RELATED Gene-based [] synonym: "scavenger receptor class A member 2" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161916,7 +145697,7 @@ synonym: "scavenger receptor class A member 1" EXACT [] synonym: "scavenger receptor type A" EXACT [] synonym: "Scvr" RELATED Gene-based [] synonym: "SR-A" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161926,7 +145707,7 @@ namespace: protein def: "A protein with core architecture consisting of a Peptidase family M1 domain (Pfam:PF01433)." [PRO:WCB] comment: Category=family. xref: PIRSF:PIRSF005502 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161939,7 +145720,7 @@ synonym: "CD14" EXACT PRO-short-label [PRO:DNx] synonym: "monocyte differentiation antigen CD14" EXACT [] synonym: "myeloid cell-specific leucine-rich glycoprotein" EXACT [] xref: PIRSF:PIRSF002017 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161955,7 +145736,7 @@ synonym: "sialic acid-binding Ig-like lectin 3" EXACT [] synonym: "siglec-3" EXACT [] synonym: "SIGLEC3" RELATED Gene-based [] xref: IUPHARobj:2601 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161975,7 +145756,7 @@ synonym: "NCR1" EXACT PRO-short-label [PRO:DNx] synonym: "NK cell-activating receptor" BROAD [PRO:DNx] synonym: "NK-p46" EXACT [] synonym: "NKp46" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -161993,7 +145774,7 @@ synonym: "NK cell-activating receptor" BROAD [PRO:DNx] synonym: "NK-p44" EXACT [] synonym: "NKp44" EXACT [] xref: PIRSF:PIRSF037963 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162013,7 +145794,7 @@ synonym: "non-MHC restricted killing associated" EXACT [] synonym: "signaling lymphocytic activation molecule 4" EXACT [] synonym: "SLAM family member 4" EXACT [] synonym: "SLAMF4" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162023,7 +145804,7 @@ namespace: protein def: "A protein with core architecture consisting of an as yet unnamed domain in the amino-terminal half and a carboxyl-terminal Lectin C-type domain (Pfam:PF00059)." [PRO:WCB] comment: Category=family. xref: PIRSF:PIRSF005558 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162046,7 +145827,7 @@ synonym: "SFE" EXACT [] synonym: "skin fibroblast elastase" EXACT [] xref: IUPHARobj:1611 xref: PIRSF:PIRSF501074 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162067,7 +145848,7 @@ synonym: "Thor" RELATED Gene-based [] synonym: "thymus orphan receptor" EXACT [] synonym: "TOR" EXACT [] xref: IUPHARobj:600 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162080,7 +145861,7 @@ synonym: "B-cell-specific transcription factor" EXACT [] synonym: "BSAP" EXACT [] synonym: "Pax-5" RELATED Gene-based [] synonym: "PAX5" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162103,7 +145884,7 @@ synonym: "PAS-4" EXACT [] synonym: "platelet collagen receptor" EXACT [] synonym: "platelet glycoprotein IV" EXACT [] synonym: "thrombospondin receptor" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162120,7 +145901,7 @@ synonym: "GP1BA" EXACT PRO-short-label [PRO:DNx] synonym: "GPIb-alpha" EXACT [] synonym: "GPIbA" EXACT [] xref: PIRSF:PIRSF002493 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162136,7 +145917,7 @@ synonym: "PDCD1" EXACT PRO-short-label [PRO:DNx] synonym: "protein PD-1" EXACT [] xref: IUPHARobj:2760 xref: PIRSF:PIRSF018380 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162148,7 +145929,7 @@ comment: Category=gene. Requested by=CL. synonym: "CD163" EXACT PRO-short-label [PRO:DNx] synonym: "hemoglobin scavenger receptor" EXACT [] synonym: "M130" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162169,7 +145950,7 @@ synonym: "siglec-5" EXACT [] synonym: "siglec-F" EXACT [] synonym: "SIGLEC5" EXACT PRO-short-label [PRO:DNx] synonym: "Siglecf" RELATED [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162188,7 +145969,7 @@ synonym: "OBBP1" RELATED Gene-based [] synonym: "obesity-binding protein 1" EXACT [] synonym: "siglec-6" EXACT [] synonym: "SIGLEC6" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162205,7 +145986,7 @@ synonym: "sialic acid-binding Ig-like lectin 1" EXACT [] synonym: "siglec-1" EXACT [] synonym: "SIGLEC1" EXACT PRO-short-label [PRO:DNx] synonym: "SN" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162224,7 +146005,7 @@ synonym: "nectadrin" EXACT [] synonym: "R13-Ag" EXACT [] synonym: "small cell lung carcinoma cluster 4 antigen" EXACT [] synonym: "X62 heat stable antigen" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162239,7 +146020,7 @@ synonym: "SDC1" EXACT PRO-short-label [PRO:DNx] synonym: "Synd-1" RELATED Gene-based [] synonym: "SYND1" EXACT [] xref: PIRSF:PIRSF015854 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162256,7 +146037,7 @@ synonym: "Trap" RELATED Gene-based [] synonym: "TrATPase" EXACT [] synonym: "type 5 acid phosphatase" EXACT [] xref: PIRSF:PIRSF000898 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162266,7 +146047,7 @@ namespace: protein def: "A protein with core architecture consisting of a signal sequence, a Lectin C-type domain (Pfam:PF00059), 5 or 6 EGF-like domains (Pfam:PF00008, Pfam:PF09064, or Pfam:PF07645), a transmembrane region, and a small cytoplasmic region (36-51 amino acids)." [PRO:WCB] comment: Category=family. xref: PIRSF:PIRSF001775 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162278,7 +146059,7 @@ comment: Category=gene. Requested by=CL. synonym: "Gata-3" RELATED Gene-based [] synonym: "GATA-binding factor 3" EXACT [] synonym: "GATA3" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162292,7 +146073,7 @@ synonym: "SFFV proviral integration 1 protein" EXACT [] synonym: "Sfpi-1" RELATED Gene-based [] synonym: "Sfpi1" RELATED Gene-based [] synonym: "SPI1" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162309,7 +146090,7 @@ synonym: "TfR1" EXACT [] synonym: "TFRC" EXACT PRO-short-label [PRO:DNx] synonym: "TR" RELATED [] synonym: "Trfr" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162327,7 +146108,7 @@ synonym: "TNF-related activation protein" EXACT [] synonym: "TNFSF5" RELATED Gene-based [] synonym: "TRAP" BROAD Gene-based [PRO:DNx] xref: PIRSF:PIRSF016527 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162344,7 +146125,7 @@ synonym: "receptor activator of NF-KB" EXACT [] synonym: "TNFRSF11A" EXACT PRO-short-label [PRO:DNx] xref: IUPHARobj:1881 xref: PIRSF:PIRSF038806 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162361,7 +146142,7 @@ synonym: "TNFRSF7" RELATED Gene-based [] synonym: "tumor necrosis factor receptor superfamily member 7" EXACT [] xref: IUPHARobj:1876 xref: PIRSF:PIRSF001966 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162410,7 +146191,7 @@ synonym: "U-PAR" EXACT [] synonym: "UPAR" RELATED Gene-based [] synonym: "uPAR" EXACT [] xref: PIRSF:PIRSF002022 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162420,7 +146201,7 @@ namespace: protein def: "A protein with core architecture consisting of a signal sequence, followed by 7 Ig-like domains (Pfam:PF00047, Pfam:PF07679, or Pfam:PF07686), a transmembrane region, and a cytoplasmic Protein tyrosine kinase domain." [PRO:WCB] comment: Category=family. xref: PIRSF:PIRSF038502 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162698,7 +146479,7 @@ namespace: protein def: "A protein that is the translation product of any of the LY6 genes (LY6A-LY6I)." [PRO:CNA] comment: Category=family. xref: PIRSF:PIRSF002021 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162775,7 +146556,7 @@ name: collagen alpha chain namespace: protein def: "A protein that is a component of collagen. Collagens are trimeric molecules in which each chain comprises a repeating Gly-X-Y triplet, in which X and Y can be any residue but are usually proline and hydroxyproline, respectively. This results in a left-handed helix that combines with other two to form a triple-helical structure." [Pfam:PF01391, PMID:15788652, PMID:1639194] comment: Category=family. -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162815,7 +146596,7 @@ synonym: "zinc finger and BTB domain-containing protein 27" EXACT [] synonym: "zinc finger protein 51" EXACT [] synonym: "ZNF51" RELATED Gene-based [] xref: IUPHARobj:2957 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162837,7 +146618,7 @@ synonym: "RAG-1" EXACT [] synonym: "RAG1" EXACT PRO-short-label [PRO:DNx] synonym: "RING finger protein 74" EXACT [] synonym: "RNF74" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162848,7 +146629,7 @@ def: "A protein that is a translation product of the human RAG2 gene or a 1:1 or comment: Category=gene. Requested by=CL. synonym: "RAG-2" EXACT [] synonym: "RAG2" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162875,7 +146656,7 @@ synonym: "lymphocyte pore-forming protein" EXACT [] synonym: "P1" RELATED [] synonym: "PFP" RELATED Gene-based [] synonym: "PRF1" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162892,7 +146673,7 @@ synonym: "Krox-20" RELATED Gene-based [] synonym: "KROX20" RELATED Gene-based [] synonym: "Zfp-25" RELATED Gene-based [] synonym: "zinc finger protein Krox-20" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162935,7 +146716,7 @@ namespace: protein def: "A protein that contains one copy of the T-box domain (Pfam:PF00907) and it is involved in the anterior neural specification." [PMID:10750050, PMID:12210112] comment: Category=family. synonym: "Eomes/Tbr1/Tbx21 family protein" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162955,7 +146736,7 @@ synonym: "Gb3 synthase" EXACT [] synonym: "globotriaosylceramide synthase" EXACT [] synonym: "P1/Pk synthase" EXACT [] synonym: "UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162970,7 +146751,7 @@ synonym: "AXL" EXACT PRO-short-label [PRO:DNx] synonym: "AXL oncogene" EXACT [] synonym: "UFO" RELATED Gene-based [] xref: IUPHARobj:1835 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162982,7 +146763,7 @@ comment: Category=gene. synonym: "BEST4" EXACT PRO-short-label [PRO:DNx] synonym: "vitelliform macular dystrophy 2-like protein 2" EXACT [] synonym: "VMD2L2" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -162992,7 +146773,7 @@ namespace: protein def: "A protein that is a translation product of the human CCK gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "CCK" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163025,7 +146806,7 @@ comment: Category=gene. Requested by=CL. synonym: "C/EBP alpha" EXACT [] synonym: "CEBP" RELATED Gene-based [] synonym: "CEBPA" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163037,7 +146818,7 @@ comment: Category=gene. Requested by=CL. synonym: "C/EBP epsilon" EXACT [] synonym: "CEBPE" EXACT PRO-short-label [PRO:DNx] synonym: "Gm294" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163051,7 +146832,7 @@ synonym: "CHODL" EXACT PRO-short-label [PRO:DNx] synonym: "PRED12" RELATED Gene-based [] synonym: "transmembrane protein MT75" EXACT [] synonym: "UNQ872/PRO1890" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163078,7 +146859,7 @@ synonym: "CD200 receptor-like 3" EXACT [] synonym: "Cd200r3" EXACT PRO-short-label [PRO:DNx] synonym: "CD200RLb" EXACT [] synonym: "cell surface glycoprotein OX2 receptor 3" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163091,7 +146872,7 @@ synonym: "Cd209b" EXACT PRO-short-label [PRO:DNx] synonym: "DC-SIGN-related protein 1" EXACT [] synonym: "DC-SIGNR1" EXACT [] synonym: "OtB7" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163105,7 +146886,7 @@ synonym: "TDT" RELATED Gene-based [] synonym: "terminal addition enzyme" EXACT [] synonym: "terminal deoxynucleotidyltransferase" EXACT [] synonym: "terminal transferase" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163118,7 +146899,7 @@ synonym: "EPER" RELATED Gene-based [] synonym: "EPO" BROAD Gene-based [PRO:DNx] synonym: "EPP" RELATED Gene-based [] synonym: "EPX" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163147,7 +146928,7 @@ synonym: "FGF-8" EXACT [] synonym: "FGF8" EXACT PRO-short-label [PRO:DNx] synonym: "HBGF-8" RELATED [] synonym: "heparin-binding growth factor 8" RELATED [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163162,7 +146943,7 @@ synonym: "G0/G1 switch regulatory protein 7" EXACT [] synonym: "G0S7" RELATED Gene-based [] synonym: "proto-oncogene protein c-fos" EXACT [] synonym: "transcription factor AP-1 subunit c-Fos" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163181,7 +146962,7 @@ synonym: "RONU" RELATED Gene-based [] synonym: "WHN" RELATED Gene-based [] synonym: "winged-helix transcription factor nude" EXACT [] xref: IUPHARobj:2958 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163198,7 +146979,7 @@ synonym: "GATA1" EXACT PRO-short-label [PRO:DNx] synonym: "GF-1" RELATED [] synonym: "GF1" RELATED Gene-based [] synonym: "NF-E1 DNA-binding protein" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163209,7 +146990,7 @@ def: "A protein that is a translation product of the human GATA2 gene or a 1:1 o comment: Category=gene. Requested by=CL. synonym: "GATA-binding protein 2" EXACT [] synonym: "GATA2" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163219,7 +147000,7 @@ namespace: protein def: "A protein that is a translation product of the human GFAP gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. Requested by=CL. synonym: "GFAP" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163280,7 +147061,7 @@ synonym: "IL17Rh1" EXACT [] synonym: "interleukin-17B receptor" EXACT [] synonym: "UNQ2501/PRO19612" RELATED Gene-based [] xref: IUPHARobj:1739 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163299,7 +147080,7 @@ synonym: "ST2" RELATED Gene-based [] synonym: "Ste2" RELATED Gene-based [] synonym: "T1" RELATED Gene-based [] xref: IUPHARobj:1735 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163367,7 +147148,7 @@ comment: Category=gene. synonym: "KISS1" EXACT PRO-short-label [PRO:DNx] synonym: "kisspeptin-1" EXACT [] synonym: "PP5098" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163385,7 +147166,7 @@ synonym: "MAFA-like receptor" EXACT [] synonym: "MAFAL" RELATED Gene-based [] synonym: "mast cell function-associated antigen" EXACT [] synonym: "mast cell function-associated antigen 2F1" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163401,7 +147182,7 @@ synonym: "Ly49" RELATED Gene-based [] synonym: "Ly49A" RELATED Gene-based [] synonym: "lymphocyte antigen 49a" EXACT [] synonym: "T lymphocyte antigen A1" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163416,7 +147197,7 @@ synonym: "ly-49c" EXACT [] synonym: "Ly49C" RELATED Gene-based [] synonym: "lymphocyte antigen 49c" EXACT [] synonym: "T-cell surface glycoprotein Ly-49C" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163431,7 +147212,7 @@ synonym: "Ly49-d" RELATED Gene-based [] synonym: "Ly49d" RELATED Gene-based [] synonym: "lymphocyte antigen 49d" EXACT [] synonym: "T-cell surface glycoprotein Ly-49D" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163446,7 +147227,7 @@ synonym: "Ly49-h" RELATED Gene-based [] synonym: "Ly49H" RELATED Gene-based [] synonym: "lymphocyte antigen 49h" EXACT [] synonym: "T-cell surface glycoprotein Ly-49H" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163463,7 +147244,7 @@ synonym: "NGAL" RELATED Gene-based [] synonym: "oncogene 24p3" EXACT [] synonym: "p25" BROAD [PRO:DNx] synonym: "SV-40-induced 24P3 protein" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163486,7 +147267,7 @@ synonym: "lectin galactoside-binding soluble 1" EXACT [] synonym: "LGALS1" EXACT PRO-short-label [PRO:DNx] synonym: "putative MAPK-activating protein PM12" EXACT [] synonym: "S-Lac lectin 1" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163502,7 +147283,7 @@ synonym: "LIM homeobox protein 3" EXACT [] synonym: "Lim-3" RELATED Gene-based [] synonym: "Lim3" RELATED Gene-based [] synonym: "Plim" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163516,7 +147297,7 @@ synonym: "lactoferrin" EXACT [] synonym: "LF" RELATED Gene-based [] synonym: "LTF" EXACT PRO-short-label [PRO:DNx] synonym: "talalactoferrin" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163531,7 +147312,7 @@ synonym: "Lcn" RELATED Gene-based [] synonym: "LDC" RELATED Gene-based [] synonym: "LUM" EXACT PRO-short-label [PRO:DNx] synonym: "SLRR2D" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163544,7 +147325,7 @@ synonym: "Meis1-related protein 1" EXACT [] synonym: "MEIS2" EXACT PRO-short-label [PRO:DNx] synonym: "MRG1" RELATED Gene-based [] synonym: "Stra10" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163559,7 +147340,7 @@ synonym: "proto-oncogene c-Mer" EXACT [] synonym: "proto-oncogene tyrosine-protein kinase MER" EXACT [] synonym: "receptor tyrosine kinase MerTK" EXACT [] xref: IUPHARobj:1837 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163570,7 +147351,7 @@ def: "A protein that is a translation product of the human MPO gene or a 1:1 ort comment: Category=gene. Requested by=CL. synonym: "MPO" EXACT PRO-short-label [PRO:DNx] xref: IUPHARobj:2789 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163581,7 +147362,7 @@ def: "A protein that is a translation product of the human MYB gene or a 1:1 ort comment: Category=gene. Requested by=CL. synonym: "MYB" EXACT PRO-short-label [PRO:DNx] synonym: "proto-oncogene c-Myb" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163593,7 +147374,7 @@ comment: Category=gene. synonym: "brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1" EXACT [] synonym: "BTCL1" RELATED Gene-based [] synonym: "NETO1" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163623,7 +147404,7 @@ synonym: "laminet-1" EXACT [] synonym: "LMNT1" RELATED Gene-based [] synonym: "NTNG1" EXACT PRO-short-label [PRO:DNx] synonym: "UNQ571/PRO1133" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163635,7 +147416,7 @@ comment: Category=gene. synonym: "beta-neoendorphin-dynorphin" EXACT [] synonym: "PDYN" EXACT PRO-short-label [PRO:DNx] synonym: "preprodynorphin" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163649,7 +147430,7 @@ synonym: "MBP" RELATED Gene-based [] synonym: "Mbp-1" RELATED Gene-based [] synonym: "PRG2" EXACT PRO-short-label [PRO:DNx] synonym: "proteoglycan 2" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163669,7 +147450,7 @@ def: "A protein that is a translation product of the human PVALB gene or a 1:1 o comment: Category=gene. synonym: "Pva" RELATED Gene-based [] synonym: "PVALB" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163681,7 +147462,7 @@ comment: Category=gene. synonym: "reeler protein" EXACT [] synonym: "RELN" EXACT PRO-short-label [PRO:DNx] synonym: "Rl" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163712,7 +147493,7 @@ synonym: "RNase 2" EXACT [] synonym: "RNase UpI-2" EXACT [] synonym: "RNASE2" EXACT PRO-short-label [PRO:DNx] synonym: "RNS2" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163726,7 +147507,7 @@ synonym: "ribonuclease 3" RELATED [] synonym: "RNase 3" EXACT [] synonym: "RNASE3" EXACT PRO-short-label [PRO:DNx] synonym: "RNS3" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163748,7 +147529,7 @@ synonym: "polyomavirus enhancer-binding protein 2 alpha B subunit" EXACT [] synonym: "RUNX1" EXACT PRO-short-label [PRO:DNx] synonym: "SL3-3 enhancer factor 1 alpha B subunit" EXACT [] synonym: "SL3/AKV core-binding factor alpha B subunit" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163774,7 +147555,7 @@ synonym: "UP1" EXACT [] synonym: "urinary protein 1" EXACT [] synonym: "urine protein 1" EXACT [] synonym: "Utg" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163788,7 +147569,7 @@ synonym: "Hhg1" RELATED Gene-based [] synonym: "SHH" EXACT PRO-short-label [PRO:DNx] synonym: "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains" EXACT [] synonym: "ShhNC" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163805,7 +147586,7 @@ synonym: "PRSN" RELATED Gene-based [] synonym: "SNCG" EXACT PRO-short-label [PRO:DNx] synonym: "SR" EXACT [] synonym: "synoretin" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163816,7 +147597,7 @@ def: "A protein that is a translation product of the human SOX2 gene or a 1:1 or comment: Category=gene. synonym: "Sox-2" RELATED Gene-based [] synonym: "SOX2" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163828,7 +147609,7 @@ comment: Category=gene. synonym: "KIAA2036" RELATED Gene-based [] synonym: "SSPO" EXACT PRO-short-label [PRO:DNx] synonym: "SSPOP" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163840,7 +147621,7 @@ comment: Category=gene. synonym: "growth hormone release-inhibiting factor" EXACT [] synonym: "Smst" RELATED Gene-based [] synonym: "SST" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163857,7 +147638,7 @@ synonym: "Tac2" RELATED Gene-based [] synonym: "TAC3" EXACT PRO-short-label [PRO:DNx] synonym: "UNQ585/PRO1155" RELATED Gene-based [] synonym: "ZNEUROK1" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163875,7 +147656,7 @@ synonym: "T-cell leukemia/lymphoma protein 5" EXACT [] synonym: "TAL-1" EXACT [] synonym: "TAL1" EXACT PRO-short-label [PRO:DNx] synonym: "TCL5" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163888,7 +147669,7 @@ synonym: "TH" EXACT PRO-short-label [PRO:DNx] synonym: "TYH" RELATED Gene-based [] synonym: "tyrosine 3-hydroxylase" EXACT [] xref: IUPHARobj:1243 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163904,7 +147685,7 @@ synonym: "p24 family protein gamma-1" EXACT [] synonym: "p24gamma1" EXACT [] synonym: "putative T1/ST2 receptor-binding protein" EXACT [] synonym: "TMED1" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163917,7 +147698,7 @@ synonym: "vasoactive intestinal peptides" EXACT [PRO:DNx] synonym: "vasoactive intestinal polypeptides" EXACT [PRO:DNx] synonym: "vasoactive intestinal polypeptides precursor" EXACT [] synonym: "VIP" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -163928,8 +147709,8 @@ def: "An organic amino compound that consists of amino acid residues (unmodified comment: Category=polymer. synonym: "peptide" NARROW [PRO:DAN] synonym: "polypeptide" NARROW [PRO:DAN] -is_a: CHEBI:50047 ! organic amino compound -relationship: has_constituent_monomer CHEBI:33708 {minCardinality="2"} ! amino-acid residue +is_a: CHEBI:50047 +relationship: has_constituent_monomer CHEBI:33708 {minCardinality="2"} [Term] id: PR:000018264 @@ -163939,7 +147720,7 @@ def: "A protein that is produced as the result of proteolytic processing of a lo synonym: "ClvPrd" EXACT PRO-short-label [PRO:DAN] synonym: "peptide" NARROW [PRO:DAN] synonym: "polypeptide" NARROW [PRO:DAN] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein intersection_of: PR:000000001 ! protein intersection_of: output_of GO:0016485 ! protein processing @@ -164420,7 +148201,7 @@ name: integrin alpha namespace: protein def: "A protein that is composed of a long N-terminal extracellular domain, a transmembrane domain and a short cytoplasmic C-terminal domain. The N-terminal domain contains beta-propeller repeats (interrupted by an A domain in a subset of integrins alpha), while the C-terminal domain contains a GFFxR motif." [PMID:19693543] comment: Category=family. Integrins are heterodimeric complexes of an alpha and a beta subunit. They are a structurally elaborate family of adhesion molecules that transmit signals bidirectionally across the plasma membrane by undergoing large-scale structural rearrangements. By regulating cell-cell and cell-matrix contacts, integrins participate in a wide-range of biological interactions including development, tissue repair, angiogenesis, inflammation and hemostasis. [PMID:10402956, PMID:11988479, PMID:9676575]. -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -164440,7 +148221,7 @@ namespace: protein def: "A protein that in active form is a serine protease that cleaves peptide bonds on the carboxyl side of lysine or arginine amino acids within amino acid chains." [PRO:DAN, Wikipedia:Trypsin] comment: Category=family. synonym: "PRSS" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -164485,7 +148266,7 @@ synonym: "iroquois homeobox protein 6" EXACT [] synonym: "IRX6" EXACT PRO-short-label [PRO:DNx] synonym: "IRX7" RELATED Gene-based [] synonym: "IRXB3" RELATED Gene-based [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -164495,7 +148276,7 @@ namespace: protein def: "A protein that is a standalone version of the Hormone_1 domain (Pfam:PF00103). In the immature form, the domain is preceded by a signal peptide." [PRO:DAN] comment: Category=family. synonym: "fam:GH1" EXACT PRO-short-label [PRO:DNx] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -164508,7 +148289,7 @@ synonym: "7TM receptor" BROAD [IUPHARfam:694] synonym: "fam:GPCR" EXACT PRO-short-label [PRO:DAN] synonym: "seven-transmembrane receptor" BROAD [IUPHARfam:694] xref: IUPHARfam:694 -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein intersection_of: PR:000000001 ! protein intersection_of: capable_of GO:0004930 ! G protein-coupled receptor activity @@ -164527,7 +148308,7 @@ synonym: "C20orf103" RELATED Gene-based [] synonym: "LAMP-5" EXACT [] synonym: "LAMP5" EXACT PRO-short-label [PRO:DNx] synonym: "lysosome-associated membrane protein 5" EXACT [] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -164554,7 +148335,7 @@ name: eukaryotic protein namespace: protein def: "A protein that is encoded in the genome of some Eukaryota." [PRO:DAN] synonym: "Eukaryota protein" EXACT [PRO:DAN] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein intersection_of: PR:000000001 ! protein intersection_of: only_in_taxon NCBITaxon:2759 ! Eukaryota @@ -164583,7 +148364,7 @@ comment: Category=modification. synonym: "glycated protein" EXACT [PRO:DAN] synonym: "glycosylated protein" EXACT [PRO:DAN] synonym: "Prot/GlycoRes+" EXACT PRO-short-label [PRO:DAN] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -164663,7 +148444,7 @@ synonym: "fam:chan" EXACT PRO-short-label [PRO:DAN] synonym: "nonselective channel protein" EXACT [PRO:XQ] synonym: "pore class transporter protein" EXACT [PRO:XQ] synonym: "pore protein" EXACT [PRO:XQ] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein intersection_of: PR:000000001 ! protein intersection_of: capable_of GO:0015267 ! channel activity @@ -164675,7 +148456,7 @@ name: leukocyte immunoglobulin-like receptor subfamily member namespace: protein comment: Category=family. Requested by=HPO/MPO. synonym: "fam:LILR" EXACT PRO-short-label [PRO:DAN] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -164685,7 +148466,7 @@ namespace: protein def: "A protein that is a translation product of a gene that encodes a standalone Insulin (Pfam:PF00049) domain preceded by a signal peptide." [PRO:DAN] comment: Category=family. synonym: "fam:INS" EXACT PRO-short-label [PRO:DAN] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -164708,7 +148489,7 @@ namespace: protein def: "A protein that is a translation product of the mouse Ren1 or Ren2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:DAN] comment: Category=family. synonym: "fam:angiotensinogenase" EXACT PRO-short-label [PRO:DAN] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -164740,7 +148521,7 @@ namespace: protein def: "A protein that is a translation product of the human HBA1, HBA2, HBB, HBD, HBE1, HBG1, HBG2, HBM, HBQ1, or HBZ genes, 1:1 orthologs thereof, or semi-orthologs thereof." [PRO:DAN] comment: Category=family. synonym: "fam:Hb" EXACT PRO-short-label [PRO:DAN] -is_a: CHEBI:36080 ! protein +is_a: CHEBI:36080 is_a: PR:000000001 ! protein [Term] @@ -172463,7 +156244,7 @@ name: system def: "A material entity consisting of multiple components that are causally integrated." [] is_a: BFO:0000040 ! material entity property_value: editor_note "May be replaced by a BFO class, as discussed in http://www.jbiomedsem.com/content/4/1/43" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "http://www.jbiomedsem.com/content/4/1/43" xsd:string [Term] @@ -173512,9 +157293,8 @@ xref: NCIT:C52556 xref: UMLS:C1709369 {source="ncithesaurus:Ovarian_Follicle_Fluid"} xref: Wikipedia:Follicular_fluid is_a: CARO:0000000 ! anatomical entity -is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000463 ! organism substance -relationship: has_part CHEBI:17089 ! glycoprotein +relationship: has_part CHEBI:17089 relationship: has_part UBERON:0000456 ! secretion of exocrine gland relationship: has_part UBERON:0007779 ! transudate relationship: located_in UBERON:0000039 ! follicular antrum @@ -174649,10 +158429,9 @@ xref: UMLS:C0043519 {source="ncithesaurus:Zona_Pellucida"} xref: VHOG:0000720 xref: Wikipedia:Zona_pellucida xref: ZFA:0001111 -is_a: PR:000050567 ! protein-containing material entity -is_a: UBERON:0000476 ! acellular anatomical structure +is_a: UBERON:0005764 ! acellular membrane relationship: bounding_layer_of CL:0000023 ! oocyte -relationship: has_part CHEBI:17089 ! glycoprotein +relationship: has_part CHEBI:17089 relationship: part_of UBERON:0000992 ! ovary relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/81/Gray3.png" xsd:anyURI @@ -175980,7 +159759,6 @@ id: UBERON:0000202 name: glial blood brain barrier namespace: uberon def: "A blood brain barrier composed of glial cells." [https://orcid.org/0000-0002-6601-2165] -xref: FBbt:00007091 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000120 ! blood brain barrier intersection_of: UBERON:0000120 ! blood brain barrier @@ -178813,7 +162591,7 @@ xref: UMLS:C0026727 {source="ncithesaurus:Mucus"} xref: Wikipedia:Mucus is_a: UBERON:0000456 ! secretion of exocrine gland is_a: UBERON:0006314 ! bodily fluid -relationship: has_part CHEBI:37395 ! mucopolysaccharide +relationship: has_part CHEBI:37395 relationship: has_quality PATO:0000998 ! viscous relationship: produced_by UBERON:0000344 ! mucosa property_value: UBPROP:0000007 "mucoid" xsd:string @@ -179931,14 +163709,14 @@ property_value: UBPROP:0000008 "Compared to terrestial animals, the cornea of ze id: UBERON:0000965 name: lens of camera-type eye namespace: uberon -def: "Transparent part of camera-type eye that helps to refract light to be focused on the retina." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Lens_(anatomy)] -comment: The lens is avascular and nourished by diffusion from the aqueous and vitreous +def: "A transparent and refractive lens located posterior to the iris. The lens of camera-type eye refracts light to be focused on the retina." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Lens_(anatomy)] +comment: The lens is avascular and nourished by diffusion from the aqueous and vitreous humors. subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "camera-type eye lens" EXACT [GO:0002088] -synonym: "crystalline lens" RELATED [BTO:0000723] +synonym: "crystalline lens" RELATED [BTO:0000723, PMID:36055924] synonym: "eye lens" EXACT SENSU [] synonym: "lens" EXACT SENSU [] synonym: "lens crystallina" EXACT [Wikipedia:Lens_(anatomy)] @@ -182834,7 +166612,7 @@ is_a: UBERON:0007779 ! transudate is_a: UBERON:0007794 {source="FMA"} ! secretion of serous gland intersection_of: UBERON:0007779 ! transudate intersection_of: produced_by CL:0000214 ! synovial cell -relationship: has_part CHEBI:16336 ! hyaluronic acid +relationship: has_part CHEBI:16336 relationship: located_in UBERON:0007617 ! synovial cavity of joint relationship: produced_by CL:0000214 ! synovial cell property_value: UBPROP:0000001 "Portion of organism substance that is a clear fluid that occupies the space in synovial joints.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005154", ontology="TAO", source="ZFIN:curator"} @@ -183540,7 +167318,7 @@ xref: ncithesaurus:Heart_Muscle xref: TAO:0005280 xref: Wikipedia:Cardiac_muscle xref: ZFA:0005280 -is_a: UBERON:0002036 ! striated muscle tissue +is_a: UBERON:8600006 ! visceral striated muscle tissue intersection_of: UBERON:0002036 ! striated muscle tissue intersection_of: has_part CL:0000746 ! cardiac muscle cell disjoint_from: UBERON:0001134 ! skeletal muscle tissue @@ -187906,7 +171684,6 @@ xref: UMLS:C0018120 {source="ncithesaurus:Ovarian_Follicle"} xref: VHOG:0001536 xref: Wikipedia:Ovarian_follicle xref: ZFA:0001110 -is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:8450001 ! egg follicle relationship: develops_from UBERON:0005296 {source="Wikipedia"} ! ovary sex cord @@ -188479,7 +172256,6 @@ is_a: UBERON:0005904 ! duct of male reproductive system relationship: channel_for CL:0000019 ! sperm relationship: channels_into UBERON:0003959 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! rete testis relationship: contains_process GO:0007283 ! spermatogenesis -relationship: contains_process GO:0051321 ! meiotic cell cycle relationship: develops_from UBERON:0005297 {source="Wikipedia"} ! testis sex cord relationship: part_of UBERON:0000473 ! testis property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/49/Seminiferous_tubule_and_sperm_low_mag.jpg" xsd:anyURI @@ -194362,7 +178138,7 @@ xref: Wikipedia:Enamel_organ xref: XAO:0004198 is_a: UBERON:0010365 {source="VSAO"} ! odontoid tissue is_a: UBERON:4000013 ! mineralized skeletal tissue -relationship: composed_primarily_of CHEBI:52255 {proportion="85", source="Wikipedia:ENAM"} ! hydroxylapatite +relationship: composed_primarily_of CHEBI:52255 {proportion="85", source="Wikipedia:ENAM"} relationship: develops_from UBERON:0011588 {source="VSAO"} ! pre-enamel relationship: never_in_taxon NCBITaxon:9359 {source="PMID:19730686"} relationship: never_in_taxon NCBITaxon:9816 {source="PMID:19730686"} @@ -195905,7 +179681,7 @@ intersection_of: UBERON:0000476 ! acellular anatomical structure intersection_of: bounding_layer_of UBERON:0000965 ! lens of camera-type eye relationship: bounding_layer_of UBERON:0000965 ! lens of camera-type eye relationship: develops_from UBERON:0005614 {source="EHDAA2"} ! lens anterior epithelium -relationship: has_part CHEBI:35722 ! sulfated glycosaminoglycan +relationship: has_part CHEBI:35722 relationship: has_part GO:0005587 ! collagen type IV trimer relationship: has_quality PATO:0000964 ! transparent property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/55/Gray883.png" xsd:anyURI @@ -197110,7 +180886,7 @@ xref: Wikipedia:Sebaceous_glands#Sebum is_a: UBERON:0000456 ! secretion of exocrine gland intersection_of: UBERON:0000456 ! secretion of exocrine gland intersection_of: produced_by UBERON:0001821 ! sebaceous gland -relationship: has_part CHEBI:15440 ! squalene +relationship: has_part CHEBI:15440 relationship: produced_by UBERON:0001821 ! sebaceous gland property_value: UBPROP:0000008 "The composition of sebum varies across species. In humans, the lipid content is as follows: 25% wax monoesters, 41% triglycerides, 16% free fatty acids, 12% squalene; Sapienic acid is a sebum fatty acid that is unique to humans." xsd:string property_value: UBPROP:0000009 "waterproofs skin" xsd:string @@ -198370,7 +182146,7 @@ xref: Wikipedia:Breast_milk is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0006314 ! bodily fluid is_a: UBERON:0006539 ! mammary gland fluid/secretion -relationship: has_part CHEBI:18059 ! lipid +relationship: has_part CHEBI:18059 relationship: has_part PR:000028527 ! casein derived peptide relationship: output_of GO:0007595 ! lactation property_value: editor_note "to axiomatize the different forms of mammary gland secretion an ontology of the phases of pregnancy/lactation is required. Using the existing GO def of lactation is circular." xsd:string @@ -198404,6 +182180,7 @@ id: UBERON:0001916 name: endothelium of arteriole namespace: uberon def: "An endothelium that is part of an arteriole [Automatically generated definition]." [OBOL:automatic] +subset: human_reference_atlas synonym: "arteriole endothelium" EXACT [] xref: EMAPA:36286 xref: FMA:62115 @@ -198415,6 +182192,7 @@ is_a: UBERON:0008339 ! microvascular endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001980 ! arteriole relationship: part_of UBERON:0001980 ! arteriole +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0001917 @@ -199218,9 +182996,9 @@ is_a: UBERON:0006314 ! bodily fluid intersection_of: UBERON:0000456 ! secretion of exocrine gland intersection_of: produced_by UBERON:0002107 ! liver relationship: capable_of_part_of GO:0007586 ! digestion -relationship: has_part CHEBI:16990 {composition="0.3% in humans"} ! bilirubin IXalpha -relationship: has_part CHEBI:22868 ! bile salt -relationship: has_part CHEBI:36277 ! bile acid salt +relationship: has_part CHEBI:16990 {composition="0.3% in humans"} +relationship: has_part CHEBI:22868 +relationship: has_part CHEBI:36277 relationship: has_quality PATO:0001735 ! liquid configuration relationship: produced_by UBERON:0002107 ! liver property_value: UBPROP:0000008 "In many species, bile is stored in the gallbladder and upon eating is discharged into the duodenum." xsd:string @@ -199471,6 +183249,7 @@ name: blood vessel namespace: uberon def: "A vessel through which blood circulates in the body." [BTO:0001102, Wikipedia:Blood_vessel] subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core @@ -199513,6 +183292,7 @@ relationship: has_part CL:0000071 {source="AEO"} ! blood vessel endothelial cell relationship: has_part UBERON:0007500 {source="EHDAA2"} ! epithelial tube open at both ends relationship: has_quality PATO:0002045 ! dendritic relationship: part_of UBERON:0004537 ! blood vasculature +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg" xsd:anyURI property_value: editor_note "consider adopting the EMAPA superclass 'vascular element', which includes microvasculature (e.g. capillaries), vascular plexus" xsd:string property_value: UBPROP:0000001 "Any of the vessels through which blood circulates in the body. [XAO:0001011_][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001250", ontology="VHOG", source="http://bgee.unil.ch/"} @@ -204456,6 +188236,32 @@ relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: surrounded_by UBERON:0001484 ! articular capsule property_value: UBPROP:0000001 "Is a joint that is located at the point of contact of articulating bones allowing movement. The joint has a capsule containing synovial fluid surrounding the articulating bone surfaces.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005153", ontology="TAO", source="ZFIN:Curator"} +[Term] +id: UBERON:0002222 +name: perichondrium +namespace: uberon +def: "Fibrous connective tissue that surrounds cartilage." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/26, PSPUB:0000170, VSAO:0000036] +subset: pheno_slim +subset: uberon_slim +subset: vertebrate_core +synonym: "cartilage connective tissue" RELATED [] +synonym: "perichondral region of cartilage" RELATED [] +synonym: "perichondral region of cartilage element" RELATED [] +xref: AAO:0010445 +xref: BTO:0005089 +xref: EMAPA:35676 +xref: FMA:75446 +xref: MA:0003008 +xref: SCTID:11881003 +xref: TAO:0001643 +xref: VSAO:0000036 +xref: Wikipedia:Perichondrium +xref: XAO:0004049 +xref: ZFA:0001634 +is_a: UBERON:0002384 {source="VSAO"} ! connective tissue +relationship: bounding_layer_of UBERON:0007844 ! cartilage element +property_value: UBPROP:0000001 "Portion of connective tissue which surrounds cartilage.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001643", ontology="TAO", source="TAO:wd"} + [Term] id: UBERON:0002224 name: thoracic cavity @@ -204737,8 +188543,8 @@ is_a: UBERON:0002384 ! connective tissue is_a: UBERON:0004121 ! ectoderm-derived structure relationship: contributes_to_morphology_of UBERON:0001066 ! intervertebral disk relationship: develops_from UBERON:0002328 {editor="mah", source="ISBN:0073040584", source="Wikipedia"} ! notochord -relationship: has_part CHEBI:37397 ! chondroitin sulfate -relationship: has_part CHEBI:60924 ! keratan sulfate +relationship: has_part CHEBI:37397 +relationship: has_part CHEBI:60924 relationship: has_part CL:0000138 ! chondrocyte relationship: has_part UBERON:0011860 ! collection of collagen fibrils relationship: part_of UBERON:0001066 ! intervertebral disk @@ -205567,6 +189373,7 @@ id: UBERON:0002303 name: juxtaglomerular apparatus namespace: uberon def: "An anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate[GO]. a microscopic structure in the kidney, which regulates the function of each nephron. The juxtaglomerular apparatus is named for its proximity to the glomerulus: it is found between the vascular pole of the renal corpuscle and the returning distal convoluted tubule of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells (also known as granular cells)[WP]." [GO:0072206, Wikipedia:Juxtaglomerular_apparatus] +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "complexus juxtaglomerularis" EXACT LATIN [] @@ -205589,6 +189396,7 @@ relationship: has_part CL:0000648 ! kidney granular cell relationship: has_part CL:0002173 ! extraglomerular mesangial cell relationship: has_part UBERON:0002335 ! macula densa relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0002304 @@ -208683,7 +192491,7 @@ xref: ZFA:0005622 is_a: UBERON:0004755 ! skeletal tissue disjoint_from: UBERON:0002481 {source="https://github.com/obophenotype/uberon/issues/117"} ! bone tissue relationship: contributes_to_morphology_of UBERON:0001434 ! skeletal system -relationship: has_part CHEBI:18085 ! glycosaminoglycan +relationship: has_part CHEBI:18085 relationship: has_part CL:0000138 ! chondrocyte relationship: only_in_taxon NCBITaxon:33213 ! Bilateria property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ee/Hypertrophic_Zone_of_Epiphyseal_Plate.jpg" xsd:anyURI @@ -212150,8 +195958,6 @@ xref: Wikipedia:Blood_island_of_umbilical_vesicle xref: XAO:0000067 xref: ZFA:0000094 is_a: UBERON:0006598 ! presumptive structure -relationship: contains_process GO:0001525 {source="ISBN:0073040584"} ! angiogenesis -relationship: contains_process GO:0030097 {source="ISBN:0073040584"} ! hemopoiesis relationship: develops_from UBERON:0003081 ! lateral plate mesoderm relationship: has_potential_to_develop_into UBERON:0002390 ! hematopoietic system property_value: UBPROP:0000001 "Nests of developing blood cells arising late in the segmentation period from the intermediate mass, and located in the anterior-ventral tail, just posterior to the yolk extension. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000094", ontology="TAO", source="ZFIN:curator"} @@ -214903,6 +198709,7 @@ id: UBERON:0003315 name: mesenchyme of ovary namespace: uberon def: "Mesenchyme that is part of a developing ovary [Automatically generated definition]." [OBOL:automatic] +subset: human_reference_atlas synonym: "female reproductive system gonad mesenchyme" EXACT [OBOL:automatic] synonym: "female reproductive system gonada mesenchyme" EXACT [OBOL:automatic] synonym: "gonad of female reproductive system mesenchyme" EXACT [OBOL:automatic] @@ -214919,6 +198726,7 @@ is_a: UBERON:0003855 ! gonad mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0000992 ! ovary relationship: part_of UBERON:0000992 ! ovary +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0003316 @@ -215296,6 +199104,7 @@ id: UBERON:0003336 name: serosa of duodenum namespace: uberon def: "A serous membrane that is part of a duodenum [Automatically generated definition]." [OBOL:automatic] +subset: human_reference_atlas synonym: "doudenal serosa" EXACT [FMA:14948] synonym: "duodenal serosa" EXACT [FMA:14948] synonym: "duodenum serosa" EXACT [OBOL:automatic] @@ -215310,6 +199119,7 @@ is_a: UBERON:0001206 ! serosa of small intestine intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0002114 ! duodenum +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: UBPROP:0000010 "1st part serosa, 2nd - 4th adventitia" xsd:string [Term] @@ -215748,6 +199558,7 @@ id: UBERON:0003379 name: cardiac muscle of right atrium namespace: uberon def: "A portion of cardiac muscle tissue that is part of a right atrium [Automatically generated definition]." [OBOL:automatic] +subset: human_reference_atlas synonym: "cardiac muscle of cardiac right atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle of heart right atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle tissue of heart right atrium" EXACT [OBOL:automatic] @@ -215768,6 +199579,7 @@ is_a: UBERON:0004490 ! cardiac muscle tissue of atrium intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002078 ! right cardiac atrium relationship: part_of UBERON:0002078 ! right cardiac atrium +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0003380 @@ -215834,6 +199646,7 @@ id: UBERON:0003383 name: cardiac muscle tissue of interventricular septum namespace: uberon def: "A portion of cardiac muscle tissue that is part of an interventricular septum [Automatically generated definition]." [OBOL:automatic] +subset: human_reference_atlas synonym: "cardiac muscle of interventricular septum" EXACT [] synonym: "cardiac muscle tissue of interventricular septum" EXACT [FMA:84084] synonym: "interventricular septum cardiac muscle" EXACT [VHOG:0000999] @@ -215848,6 +199661,7 @@ is_a: UBERON:0004492 ! cardiac muscle tissue of cardiac septum is_a: UBERON:0004667 ! interventricular septum muscular part intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002094 ! interventricular septum +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0003384 @@ -216245,7 +200059,7 @@ is_a: UBERON:0003104 ! mesenchyme is_a: UBERON:0005292 ! extraembryonic tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002331 ! umbilical cord -relationship: has_part CHEBI:37395 {source="Wikipedia"} ! mucopolysaccharide +relationship: has_part CHEBI:37395 {source="Wikipedia"} relationship: part_of UBERON:0002331 ! umbilical cord relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: editor_note "TODO - check" xsd:string @@ -217723,6 +201537,7 @@ id: UBERON:0003517 name: kidney blood vessel namespace: uberon def: "A blood vessel that is part of a kidney [Automatically generated definition]." [OBOL:automatic] +subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core synonym: "blood vessel of kidney" EXACT [OBOL:automatic] @@ -217735,6 +201550,7 @@ is_a: UBERON:0003497 ! abdomen blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002113 ! kidney relationship: part_of UBERON:0006544 ! kidney vasculature +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0003519 @@ -217861,6 +201677,7 @@ id: UBERON:0003527 name: kidney capillary namespace: uberon def: "A capillary that is part of a kidney [Automatically generated definition]." [OBOL:automatic] +subset: human_reference_atlas subset: pheno_slim synonym: "blood capillary of kidney" EXACT [OBOL:automatic] synonym: "capillary of kidney" EXACT [OBOL:automatic] @@ -217875,6 +201692,7 @@ is_a: UBERON:0001982 ! capillary is_a: UBERON:0003517 ! kidney blood vessel intersection_of: UBERON:0001982 ! capillary intersection_of: part_of UBERON:0002113 ! kidney +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0003528 @@ -220761,8 +204579,6 @@ namespace: uberon def: "The middle limb segment of the pelvic free limb, between the autopod and stylopod segments. Includes as parts the hindlimb zeugopodial skeleton, which includes as parts the tibia and fibula, or their cartilage precursors, or evolutionary variants." [PHENOSCAPE:curators] subset: efo_slim subset: pheno_slim -synonym: "calf" NARROW [] -synonym: "calf of leg" EXACT [FMA:24984] synonym: "crus" EXACT [VSAO:0005060] synonym: "crus of hindlimb" EXACT [] synonym: "hind epipodium" RELATED INCONSISTENT [] @@ -220781,15 +204597,7 @@ synonym: "lower extremity zeugopod" EXACT [OBOL:automatic] synonym: "lower leg" EXACT HUMAN_PREFERRED [MA:0000051] synonym: "middle limb segment of hind limb" EXACT [OBOL:automatic] synonym: "middle limb segment of hindlimb" EXACT [https://orcid.org/0000-0002-6601-2165] -synonym: "posterior curral region" EXACT [FMA:24984] -synonym: "posterior leg region" EXACT [FMA:24984] -synonym: "posterior part of leg" EXACT [FMA:24984] -synonym: "posterior region of leg" EXACT [FMA:24984] -synonym: "regio cruris posterior" EXACT LATIN [FMA:24984, FMA:TA] -synonym: "regio surae" EXACT LATIN [FMA:24984, FMA:TA] synonym: "shank" EXACT [VSAO:0005060] -synonym: "sura" EXACT LATIN [FMA:24984, FMA:TA] -synonym: "sural region" EXACT [FMA:24984] synonym: "zeugopod of hind limb" EXACT [OBOL:automatic] synonym: "zeugopod of hindlimb" EXACT [OBOL:automatic] xref: EFO:0003051 @@ -220798,7 +204606,6 @@ xref: EHDAA:5165 xref: EHDAA:6190 xref: EMAPA:17496 xref: FMA:24979 -xref: FMA:24984 xref: galen:Leg xref: MA:0000051 xref: MESH:D007866 @@ -222069,7 +205876,6 @@ id: UBERON:0003918 name: kidney mesenchyme namespace: uberon def: "Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney[GO]." [GO:0072074] -subset: human_reference_atlas subset: pheno_slim synonym: "mesenchyme of kidney" EXACT [] is_a: CARO:0000000 ! anatomical entity @@ -222077,7 +205883,6 @@ is_a: UBERON:0003104 ! mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: has_potential_to_develop_into UBERON:0002113 ! kidney relationship: has_potential_to_develop_into UBERON:0002113 ! kidney -relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: editor_note "check this" xsd:string [Term] @@ -229599,59 +213404,6 @@ intersection_of: has_part UBERON:0004755 ! skeletal tissue relationship: develops_from UBERON:0002067 ! dermis relationship: has_part UBERON:0004755 ! skeletal tissue -[Term] -id: UBERON:0004757 -name: rectal salt gland -namespace: uberon -def: "An evagination of the terminal portion of the intestine that is capable of secreting high concentrations of excess sodium chloride." [http://www.briancoad.com/dictionary/complete%20dictionary.htm, UBERON:cjm] -subset: organ_slim -synonym: "digitiform gland" BROAD [http://www.briancoad.com/dictionary/complete%20dictionary.htm] -synonym: "glandula rectalis" BROAD LATIN [http://www.briancoad.com/dictionary/complete%20dictionary.htm] -synonym: "rectal gland" BROAD [] -xref: BTO:0001157 -xref: SCTID:80455007 -is_a: UBERON:0003408 ! gland of digestive tract -is_a: UBERON:0004758 ! salt gland -intersection_of: UBERON:0002530 ! gland -intersection_of: capable_of GO:0055078 ! sodium ion homeostasis -intersection_of: part_of UBERON:0001052 ! rectum -relationship: never_in_taxon NCBITaxon:32523 ! Tetrapoda -relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata -relationship: part_of UBERON:0001052 ! rectum -relationship: present_in_taxon NCBITaxon:118072 -relationship: present_in_taxon NCBITaxon:119203 -property_value: UBPROP:0000009 "shark liver produces copious amounts of urea, making the shark hyperosmotic to seawater, & thus a shark acts like a fresh water fish, constantly gaining water. Excess salts are concentrated by the rectal gland and secreted" xsd:string - -[Term] -id: UBERON:0004758 -name: salt gland -namespace: uberon -def: "An organ for excreting excess salts. It is found in elasmobranchs, seabirds, and some reptiles.[WP]." [Wikipedia:Salt_gland] -subset: functional_classification -subset: organ_slim -xref: BTO:0001204 -xref: GAID:1235 -xref: MESH:D012491 -xref: Wikipedia:Salt_gland -is_a: UBERON:0002530 ! gland -intersection_of: UBERON:0002530 ! gland -intersection_of: capable_of GO:0055078 ! sodium ion homeostasis -relationship: capable_of GO:0055078 ! sodium ion homeostasis -relationship: never_in_taxon NCBITaxon:40674 ! Mammalia -relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata -property_value: UBPROP:0000008 "In sharks, salt glands are found in the rectum, but in birds and reptiles, they are found in or on the skull, in the area of the eyes, nostrils or mouth. In crocodiles, the salt is excreted through the tongue. Such glands work by active transport via sodium-potassium pump that moves salt from the blood into the gland, where it can be excreted as a concentrated solution. Salt glands function to keep salt balance, and allow marine vertebrates to drink seawater" xsd:string - -[Term] -id: UBERON:0004759 -name: cranial salt gland -namespace: uberon -def: "A salt gland located in the cranium or head region." [OBOL:automatic] -subset: organ_slim -is_a: UBERON:0004758 ! salt gland -intersection_of: UBERON:0004758 ! salt gland -intersection_of: part_of UBERON:0000033 ! head -relationship: part_of UBERON:0000033 ! head - [Term] id: UBERON:0004760 name: gland of anal canal @@ -243745,7 +227497,6 @@ namespace: uberon def: "A subdivision of a the reproductive tract in a female organism that is the site of embryo development." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "uterus" BROAD SENSU [FBbt:00004924] -xref: FBbt:00004924 xref: TADS:0000421 xref: WBbt:0006760 is_a: UBERON:0005156 ! reproductive structure @@ -248039,6 +231790,27 @@ is_a: UBERON:0005423 ! developing anatomical structure relationship: develops_from UBERON:0005087 ! tooth placode relationship: part_of UBERON:0011595 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! jaw region +[Term] +id: UBERON:0008304 +name: inner chondrogenic layer of perichondrium +namespace: uberon +def: "The perichondrium consists of two separate layers: an outer fibrous layer and inner chondrogenic layer. The chondrogenic layer remains undifferentiated and can form chondroblasts or chondrocytes." [Wikipedia:The_Free_Encyclopedia] +xref: BTO:0005090 +xref: Wikipedia:The_Free_Encyclopedia +is_a: UBERON:0002384 ! connective tissue +relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata +relationship: part_of UBERON:0002222 {source="BTO"} ! perichondrium + +[Term] +id: UBERON:0008305 +name: outer fibrous layer of perichondrium +namespace: uberon +def: "The perichondrium consists of two separate layers: an outer fibrous layer and inner chondrogenic layer. The fibrous layer contains fibroblasts, which produce collagenous fibers." [Wikipedia:The_Free_Encyclopedia] +xref: BTO:0005091 +xref: Wikipedia:The_Free_Encyclopedia +is_a: UBERON:0002384 ! connective tissue +relationship: part_of UBERON:0002222 {source="BTO"} ! perichondrium + [Term] id: UBERON:0008307 name: heart endothelium @@ -248677,11 +232449,10 @@ xref: MESH:D011663 xref: NCIT:C13273 xref: UMLS:C0034085 {source="ncithesaurus:Lung_Surfactant"} xref: Wikipedia:Pulmonary_surfactant -is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0006538 ! respiratory system fluid/secretion intersection_of: UBERON:0006538 ! respiratory system fluid/secretion intersection_of: produced_by CL:0002063 ! type II pneumocyte -relationship: has_part CHEBI:6495 ! lipoprotein +relationship: has_part CHEBI:6495 relationship: produced_by CL:0002063 ! type II pneumocyte property_value: UBPROP:0000009 "surfactant" xsd:string @@ -267260,9 +251031,9 @@ synonym: "respiratory system air" EXACT [] xref: FMA:84581 is_a: UBERON:0034947 ! gas in respiratory system intersection_of: UBERON:0034873 ! bodily gas -intersection_of: composed_primarily_of CHEBI:25805 ! oxygen atom +intersection_of: composed_primarily_of CHEBI:25805 intersection_of: located_in UBERON:0001004 ! respiratory system -relationship: composed_primarily_of CHEBI:25805 ! oxygen atom +relationship: composed_primarily_of CHEBI:25805 [Term] id: UBERON:0034875 @@ -270171,7 +253942,7 @@ is_a: UBERON:4000013 ! mineralized skeletal tissue intersection_of: UBERON:0002481 ! bone tissue intersection_of: has_quality PATO:0002444 ! mineralized relationship: develops_from UBERON:0008883 ! osteoid -relationship: has_part CHEBI:52255 ! hydroxylapatite +relationship: has_part CHEBI:52255 relationship: has_part UBERON:4000020 ! mineralized extracellular matrix property_value: UBPROP:0000004 "This class was sourced from an external ontology (vertebrate_skeletal_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/vsao.owl"} @@ -271396,7 +255167,7 @@ synonym: "floor of capsule of lymph node" EXACT [] synonym: "subcapsular sinus of lymph node ceiling" EXACT [] is_a: UBERON:0000064 ! organ part relationship: adjacent_to UBERON:0005463 ! subcapsular sinus of lymph node -relationship: dc-contributor http://orcid.org/0000-0002-2825-0621 +relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0002194 ! capsule of lymph node relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: dcterms-date "2022-02-22T17:04:49Z" xsd:dateTime @@ -271412,7 +255183,7 @@ synonym: "floor of subcapsular sinus of lymph node" EXACT [] synonym: "subcapsular sinus of lymph node floor" EXACT [] is_a: UBERON:0000064 ! organ part relationship: adjacent_to UBERON:0005463 ! subcapsular sinus of lymph node -relationship: dc-contributor http://orcid.org/0000-0002-2825-0621 +relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0002006 ! cortex of lymph node relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: dcterms-date "2022-02-22T17:16:40Z" xsd:dateTime @@ -271429,7 +255200,7 @@ is_a: UBERON:0011148 ! submucosal gland is_a: UBERON:0036225 ! respiratory system gland intersection_of: UBERON:0011148 ! submucosal gland intersection_of: part_of UBERON:0000065 ! respiratory tract -relationship: dc-contributor http://orcid.org/0000-0002-2825-0621 +relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0000065 ! respiratory tract property_value: dcterms-date "2022-03-24T14:21:59Z" xsd:dateTime @@ -271541,7 +255312,7 @@ intersection_of: UBERON:0035014 ! functional part of brain intersection_of: capable_of_part_of GO:0007601 ! visual perception intersection_of: part_of UBERON:0000956 ! cerebral cortex relationship: capable_of_part_of GO:0007601 ! visual perception -relationship: dc-contributor http://orcid.org/0000-0001-7258-9596 +relationship: dc-contributor https://orcid.org/0000-0001-7258-9596 relationship: part_of UBERON:0000956 ! cerebral cortex [Term] @@ -271559,7 +255330,7 @@ namespace: uberon def: "A structure embedded in the superior olivary complex that is driven by input pathways from the octopus cells in the cochlear nucleus and the neurons of the medial nucleus of the trapezoid body." [DOI:10.1093/oxfordhb/9780190849061.013.11] synonym: "SPON" EXACT [DOI:10.1093/oxfordhb/9780190849061.013.11] is_a: UBERON:0007247 ! nucleus of superior olivary complex -relationship: dc-contributor http://orcid.org/0000-0001-7258-9596 +relationship: dc-contributor https://orcid.org/0000-0001-7258-9596 [Term] id: UBERON:8450001 @@ -271568,7 +255339,7 @@ namespace: uberon def: "An individual reproductive unit containing a single oocyte and one or several layers of support cells (Armstrong et al., 2020)." [DOI:10.1530/REP-18-0593] is_a: UBERON:0000064 ! organ part is_a: UBERON:0005156 ! reproductive structure -relationship: dc-contributor http://orcid.org/0000-0002-6095-8718 +relationship: dc-contributor https://orcid.org/0000-0002-6095-8718 relationship: part_of UBERON:0000992 ! ovary property_value: dcterms-date "2022-04-19T11:08:10Z" xsd:dateTime property_value: seeAlso "https://github.com/obophenotype/uberon/issues/476" xsd:anyURI @@ -271593,7 +255364,7 @@ def: "Blood located in the placenta." [http://orcid.org/0000-0001-6595-0902, htt is_a: UBERON:0000178 ! blood intersection_of: UBERON:0000178 ! blood intersection_of: located_in UBERON:0001987 ! placenta -relationship: dc-contributor http://orcid.org/0000-0002-1773-2692 +relationship: dc-contributor https://orcid.org/0000-0002-1773-2692 relationship: located_in UBERON:0001987 ! placenta property_value: dcterms-date "2022-04-04T11:06:09Z" xsd:dateTime @@ -271605,7 +255376,7 @@ def: "A portion of smooth muscle tissue that is part of an iliac vein." [https:/ is_a: UBERON:0004696 ! venous system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0005610 ! iliac vein -relationship: dc-contributor http://orcid.org/0000-0002-0819-0473 +relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0005610 ! iliac vein property_value: dcterms-date "2022-06-17T14:34:50Z" xsd:dateTime @@ -271618,7 +255389,7 @@ is_a: UBERON:0001982 ! capillary is_a: UBERON:0003499 ! brain blood vessel intersection_of: UBERON:0001982 ! capillary intersection_of: part_of UBERON:0000955 ! brain -relationship: dc-contributor http://orcid.org/0000-0002-0819-0473 +relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 property_value: dcterms-date "2022-06-24T09:28:31Z" xsd:dateTime [Term] @@ -271629,7 +255400,7 @@ def: "A portion of smooth muscle tissue that is part of the thoracic aorta." [ht is_a: UBERON:0004178 ! aorta smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001515 ! thoracic aorta -relationship: dc-contributor http://orcid.org/0000-0002-0819-0473 +relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0001515 ! thoracic aorta property_value: dcterms-date "2022-06-24T09:30:54Z" xsd:dateTime @@ -271641,7 +255412,7 @@ def: "A portion of smooth muscle tissue that is part of an iliac artery." [https is_a: UBERON:0002111 ! artery smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0005609 ! iliac artery -relationship: dc-contributor http://orcid.org/0000-0002-0819-0473 +relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0005609 ! iliac artery property_value: dcterms-date "2022-06-24T09:32:07Z" xsd:dateTime @@ -271653,7 +255424,7 @@ def: "An endothelium that is part of an iliac vein." [https://orcid.org/0000-000 is_a: UBERON:0001919 ! endothelium of vein intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0005610 ! iliac vein -relationship: dc-contributor http://orcid.org/0000-0002-0819-0473 +relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0005610 ! iliac vein property_value: dcterms-date "2022-06-24T09:33:18Z" xsd:dateTime @@ -271667,7 +255438,7 @@ is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0005292 ! extraembryonic tissue intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:8480007 ! placental artery -relationship: dc-contributor http://orcid.org/0000-0002-0819-0473 +relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:8480007 ! placental artery property_value: dcterms-date "2022-06-24T09:34:25Z" xsd:dateTime @@ -271679,7 +255450,7 @@ def: "Lymphatic vessel that is part of the mesentery." [https://orcid.org/0000-0 is_a: UBERON:0001473 ! lymphatic vessel intersection_of: UBERON:0001473 ! lymphatic vessel intersection_of: part_of UBERON:0002095 ! mesentery -relationship: dc-contributor http://orcid.org/0000-0002-0819-0473 +relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0002095 ! mesentery property_value: dcterms-date "2022-06-24T09:35:29Z" xsd:dateTime @@ -271692,7 +255463,7 @@ is_a: UBERON:0001637 ! artery is_a: UBERON:0022358 ! placenta blood vessel intersection_of: UBERON:0001637 ! artery intersection_of: part_of UBERON:0001987 ! placenta -relationship: dc-contributor http://orcid.org/0000-0002-0819-0473 +relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 property_value: dcterms-date "2022-06-24T11:25:24Z" xsd:dateTime [Term] @@ -271704,7 +255475,7 @@ is_a: UBERON:0001638 ! vein is_a: UBERON:0022358 ! placenta blood vessel intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0001987 ! placenta -relationship: dc-contributor http://orcid.org/0000-0002-0819-0473 +relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 property_value: dcterms-date "2022-06-27T09:30:52Z" xsd:dateTime [Term] @@ -271715,7 +255486,7 @@ def: "A zone of skin that is above the clavicle zone in the pectoral girdle regi is_a: UBERON:0000014 ! zone of skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001421 ! pectoral girdle region -relationship: dc-contributor http://orcid.org/0000-0002-0819-0473 +relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0001421 ! pectoral girdle region property_value: dcterms-date "2022-08-29T14:17:12Z" xsd:dateTime @@ -271728,7 +255499,7 @@ synonym: "skin of posterior iliac crest region" BROAD [] is_a: UBERON:0001415 ! skin of pelvis intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0007830 ! pelvic girdle bone/zone -relationship: dc-contributor http://orcid.org/0000-0002-0819-0473 +relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0007830 ! pelvic girdle bone/zone property_value: dcterms-date "2022-08-29T14:19:16Z" xsd:dateTime @@ -271741,7 +255512,7 @@ is_a: UBERON:0000014 ! zone of skin is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0004176 ! external genitalia -relationship: dc-contributor http://orcid.org/0000-0002-0819-0473 +relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0004176 ! external genitalia property_value: dcterms-date "2022-08-30T06:55:06Z" xsd:dateTime @@ -271753,7 +255524,7 @@ def: "A zone of skin that is part of the breast." [https://orcid.org/0000-0002-0 is_a: UBERON:0001868 ! skin of chest intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0000310 ! breast -relationship: dc-contributor http://orcid.org/0000-0002-0819-0473 +relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0000310 ! breast property_value: dcterms-date "2022-08-29T14:03:54Z" xsd:dateTime @@ -271768,7 +255539,7 @@ is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0012375 ! subserosa intersection_of: UBERON:0012375 ! subserosa intersection_of: part_of UBERON:0003889 ! fallopian tube -relationship: dc-contributor http://orcid.org/0000-0002-0819-0473 +relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0003889 ! fallopian tube property_value: dcterms-date "2022-10-21T08:55:11Z" xsd:dateTime @@ -271779,7 +255550,7 @@ namespace: uberon def: "A conductive airway that branches into terminal bronchioles." [PMID:16543587, PMID:27611890] synonym: "preterminal bronchiole" EXACT [PMID:16543587] is_a: UBERON:0002186 ! bronchiole -relationship: dc-contributor http://orcid.org/0000-0001-6677-8489 +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 property_value: dcterms-date "2023-02-08T13:31:12Z" xsd:dateTime [Term] @@ -271792,7 +255563,7 @@ synonym: "lobular bronchiole epithelium" EXACT [FMA:62497] is_a: UBERON:0002051 ! epithelium of bronchiole intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:8600000 ! lobular bronchiole -relationship: dc-contributor http://orcid.org/0000-0001-6677-8489 +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: part_of UBERON:8600000 ! lobular bronchiole property_value: dcterms-date "2023-02-10T14:26:09Z" xsd:dateTime @@ -271804,7 +255575,7 @@ def: "A mucosa that is part of a lobular bronchiole." [FMA:263230] is_a: UBERON:0005039 ! mucosa of bronchiole intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:8600000 ! lobular bronchiole -relationship: dc-contributor http://orcid.org/0000-0001-6677-8489 +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: part_of UBERON:8600000 ! lobular bronchiole property_value: dcterms-date "2023-02-10T14:48:35Z" xsd:dateTime @@ -271816,10 +255587,33 @@ def: "A smooth muscle tissue that is part of a lobular bronchiole." [FMA:261081] is_a: UBERON:0004515 ! smooth muscle tissue of bronchiole intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:8600000 ! lobular bronchiole -relationship: dc-contributor http://orcid.org/0000-0001-6677-8489 +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: part_of UBERON:8600000 ! lobular bronchiole property_value: dcterms-date "2023-02-10T14:54:06Z" xsd:dateTime +[Term] +id: UBERON:8600004 +name: visceral muscle tissue +namespace: uberon +def: "A muscle tissue that is associated with soft internal organs (viscera)." [BTO:0002780, CLAO:0001295] +comment: It is quite common to refer to visceral muscles as smooth muscles, by analogy with vertebrates; however, most visceral muscles in arthropods are actually striated. {xref="https://en.wikipedia.org/wiki/Smooth_muscle", xref="FBbt:00005070", comment="PMID:8720463"} +synonym: "visceral muscle" EXACT [] {comment="BTO:0002780"} +is_a: UBERON:0002385 ! muscle tissue +relationship: composed_primarily_of CL:0008007 ! visceral muscle cell +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +property_value: dcterms-date "2023-02-16T10:17:46Z" xsd:dateTime + +[Term] +id: UBERON:8600006 +name: visceral striated muscle tissue +namespace: uberon +def: "A striated muscle tissue that is associated with soft internal organs (viscera)." [https://pressbooks.pub/rbtallitsch/chapter/chapter-6-muscle-tissue/, PMID:8720463] +synonym: "striated visceral muscle tissue" EXACT [] +is_a: UBERON:0002036 ! striated muscle tissue +is_a: UBERON:8600004 ! visceral muscle tissue +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +property_value: dcterms-date "2023-02-16T10:34:43Z" xsd:dateTime + [Term] id: http://purl.obolibrary.org/obo/D96882F1-8709-49AB-BCA9-772A67EA6C33 name: obsolete D96882F1-8709-49AB-BCA9-772A67EA6C33 @@ -271827,6 +255621,20 @@ comment: ID was moved to the CL namespace. Use CL:0017509. is_obsolete: true replaced_by: CL:0017509 +[Typedef] +id: CL:4030044 +name: has_not_completed + +[Typedef] +id: CL:4030045 +name: lacks_part +expand_expression_to: "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y" [] + +[Typedef] +id: CL:4030046 +name: lacks_plasma_membrane_part +expand_expression_to: "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)" [] + [Typedef] id: RO:0000052 name: characteristic of @@ -271977,7 +255785,7 @@ inverse_of: has_boundary ! has_boundary id: RO:0002006 name: has synaptic terminal of property_value: http://purl.org/spar/cito/citesAsAuthority http://www.ncbi.nlm.nih.gov/pubmed/22402613 -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 is_a: overlaps ! overlaps inverse_of: RO:0002130 ! has synaptic terminal in @@ -272076,11 +255884,11 @@ is_a: RO:0002222 ! temporally related to id: RO:0002100 name: has soma location namespace: fly_anatomy.ontology -def: "Relation between a neuron and an anatomical structure that its soma is part of." [FBC:DOS] def: "Relation between a neuron and an anatomical structure that its soma is part of." [] +def: "Relation between a neuron and an anatomical structure that its soma is part of." [https://orcid.org/0000-0002-7073-9172] xref: RO:0002100 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: RO:0001900 RO:0001901 domain: CL:0000540 ! neuron range: CARO:0000003 ! connected anatomical structure @@ -272093,12 +255901,12 @@ expand_expression_to: "BFO_0000051 some (GO_0043025 and BFO_0000050 some ?Y)" [] id: RO:0002101 name: fasciculates with namespace: fly_anatomy.ontology -def: "Relation between a neuron and the neuron projection bundle it fasciculates with. FOL: x fasciculates_with y iff: exists some 'neuron ; CL_0000540'(x), some 'neuron projection bundle ; CARO_0001001'(y), some 'neuron projection ; GO_0043005'(np), np part_of x AND np overlaps y AND np aligned_with y" [FBC:DOS] +def: "Relation between a neuron and the neuron projection bundle it fasciculates with. FOL: x fasciculates_with y iff: exists some 'neuron ; CL_0000540'(x), some 'neuron projection bundle ; CARO_0001001'(y), some 'neuron projection ; GO_0043005'(np), np part_of x AND np overlaps y AND np aligned_with y" [https://orcid.org/0000-0002-7073-9172] def: "relationship between a neuron and a neuron projection bundle (e.g.- tract or nerve bundle) that one or more of its projections travels through.\n" [] xref: RO:0002101 property_value: http://purl.org/spar/cito/citesAsAuthority http://www.ncbi.nlm.nih.gov/pubmed/22402613 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000118 "fasciculates with" xsd:string property_value: IAO:0000426 "(forall (?x ?y) \n (iff \n (fasciculates_with ?x ?y)\n (exists (?nps ?npbs)\n (and \n (\"neuron ; CL_0000540\" ?x)\n (\"neuron projection bundle ; CARO_0001001\" ?y) \n (\"neuron projection segment ; CARO_0001502\" ?nps)\n (\"neuron projection bundle segment ; CARO_0001500' \" ?npbs)\n (part_of ?npbs ?y) \n (part_of ?nps ?x)\n (part_of ?nps ?npbs)\n (forall (?npbss)\n (if\n (and \n (\"neuron projection bundle subsegment ; CARO_0001501\" ?npbss)\n (part_of ?npbss ?npbs) \n )\n (overlaps ?nps ?npbss)\n ))))))" xsd:string property_value: RO:0001900 RO:0001901 @@ -272113,9 +255921,8 @@ name: axon synapses in def: "Relation between a neuron and some structure its axon forms (chemical) synapses in." [] property_value: http://purl.org/spar/cito/citesAsAuthority http://www.ncbi.nlm.nih.gov/pubmed/22402613 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: RO:0001900 RO:0001901 domain: CL:0000540 ! neuron is_a: RO:0002113 ! has presynaptic terminal in @@ -272127,12 +255934,12 @@ id: RO:0002103 name: synapsed by namespace: fly_anatomy.ontology def: "Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it. " [] -def: "Relation between an anatomical structure and a neuron that chemically synapses to it." [FBC:DOS] +def: "Relation between an anatomical structure and a neuron that chemically synapses to it." [https://orcid.org/0000-0002-7073-9172] xref: RO:0002103 property_value: http://purl.org/spar/cito/citesAsAuthority http://www.ncbi.nlm.nih.gov/pubmed/22402613 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: RO:0001900 RO:0001901 is_a: RO:0002485 ! receives input from inverse_of: RO:0002120 ! synapsed to @@ -272145,9 +255952,9 @@ name: has plasma membrane part def: "Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part." [] property_value: IAO:0000112 "Every B cell[CL_0000236] has plasma membrane part some immunoglobulin complex[GO_0019814]" xsd:string property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Alexander Diehl" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string -property_value: IAO:0000117 "Lindsay Cowell" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0001-9990-8331 +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0003-1617-8244 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/19243617 property_value: RO:0001900 RO:0001901 domain: CARO:0000006 ! material anatomical entity @@ -272164,8 +255971,8 @@ comment: Relation between a neuron and the structure in which its dendrite recei xref: RO:0002110 property_value: http://purl.org/spar/cito/citesAsAuthority http://www.ncbi.nlm.nih.gov/pubmed/22402613 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000118 "synapsed in" xsd:string property_value: RO:0001900 RO:0001901 domain: CL:0000540 ! neuron @@ -272196,13 +256003,13 @@ id: RO:0002120 name: synapsed to namespace: fly_anatomy.ontology def: " Relation between a neuron and an anatomical structure (including cells) that it chemically synapses to.\n " [] -def: "Relation between a neuron and an anatomical structure that it chemically synapses to." [FBC:DOS] +def: "Relation between a neuron and an anatomical structure that it chemically synapses to." [https://orcid.org/0000-0002-7073-9172] comment: N1 synapsed_to some N2 \nExpands to:\nN1 SubclassOf ( \n has_part some (\n ‘pre-synaptic membrane ; GO:0042734’ that part_of some ( \n ‘synapse ; GO:0045202’ that has_part some (\n ‘post-synaptic membrane ; GO:0045211’ that part_of some N2)))) xref: RO:0002120 property_value: http://purl.org/spar/cito/citesAsAuthority http://www.ncbi.nlm.nih.gov/pubmed/22402613 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: RO:0001900 RO:0001901 is_a: RO:0002486 ! sends output to expand_expression_to: "BFO_0000051 some (GO_0042734 that BFO_0000050 some (GO_0045202 that BFO_0000051 some (GO_0045211 that BFO_0000050 some ?Y)))" [] @@ -272213,12 +256020,12 @@ id: RO:0002130 name: has synaptic terminal in namespace: fly_anatomy.ontology def: "A general relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input." [] -def: "A relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input." [FBC:DOS] +def: "A relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input." [https://orcid.org/0000-0002-7073-9172] comment: expands to - X overlaps some ('synapse ; GO_0045202' that part_of some ?Y) xref: RO:0002130 property_value: http://purl.org/spar/cito/citesAsAuthority http://www.ncbi.nlm.nih.gov/pubmed/22402613 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000118 "has synapse in" xsd:string property_value: RO:0001900 RO:0001901 domain: CL:0000540 ! neuron @@ -272233,7 +256040,7 @@ name: has fasciculating neuron projection def: "The relation between a neuron projection bundle and a neuron projection that is fasciculated with it." [] property_value: http://purl.org/spar/cito/citesAsAuthority http://www.ncbi.nlm.nih.gov/pubmed/22402613 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000118 "has fasciculating component" xsd:string property_value: IAO:0000426 "(forall (?x ?y) \n (iff \n (has_fasciculating_neuron_projection ?x ?y)\n (exists (?nps ?npbs) \n (and \n (\"neuron projection bundle ; CARO_0001001\" ?x)\n (\"neuron projection ; GO0043005\" ?y)\n (\"neuron projection segment ; CARO_0001502\" ?nps)\n (\"neuron projection bundle segment ; CARO_0001500\" ?npbs)\n (part_of ?nps ?y)\n (part_of ?npbs ?x)\n (part_of ?nps ?npbs)\n (forall (?npbss)\n (if\n (and \n (\"neuron projection bundle subsegment ; CARO_0001501\" ?npbss)\n (part_of ?npbss ?npbs) \n )\n (overlaps ?nps ?npbss)\n ))))))\n\n\n" xsd:string property_value: RO:0001900 RO:0001901 @@ -272247,7 +256054,7 @@ def: "A is spatially_disjoint_from B if and only if they have no parts in common subset: ro-eco property_value: editor_note "There are two ways to encode this as a shortcut relation. The other possibility to use an annotation assertion between two classes, and expand this to a disjointness axiom. " xsd:string property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/22293552 property_value: IAO:0000232 "Note that it would be possible to use the relation to label the relationship between a near infinite number of structures - between the rings of saturn and my left earlobe. The intent is that this is used for parsiomoniously for disambiguation purposes - for example, between siblings in a jointly exhaustive pairwise disjointness hierarchy" xsd:string property_value: RO:0001900 RO:0001901 @@ -272261,9 +256068,9 @@ name: develops into def: "inverse of develops from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string -property_value: IAO:0000117 "Terry Meehan" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 +property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 is_transitive: true is_a: has_potential_to_develop_into ! has potential to develop into is_a: RO:0002286 ! developmentally succeeded by @@ -272275,7 +256082,7 @@ name: expressed in def: "x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process" [] property_value: IAO:0000112 "'neural crest cell' SubClassOf expresses some 'Wnt1 gene'" xsd:string property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 domain: BFO:0000002 ! continuant range: CARO:0000006 ! material anatomical entity is_a: RO:0002330 ! genomically related to @@ -272298,7 +256105,7 @@ comment: A relation that holds between two occurrents. This is a grouping relati subset: ro-eco property_value: http://purl.org/dc/terms/source "https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1" xsd:anyURI property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 https://en.wikipedia.org/wiki/Allen%27s_interval_algebra property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends." xsd:string domain: BFO:0000003 ! occurrent @@ -272310,7 +256117,7 @@ name: developmentally contributes to def: "inverse of has developmental contribution from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: RO:0002203 part_of is_a: has_potential_to_developmentally_contribute_to ! has potential to developmentally contribute to is_a: RO:0002286 ! developmentally succeeded by @@ -272320,7 +256127,7 @@ id: RO:0002257 name: developmentally induces def: "Inverse of developmentally induced by" [] property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: RO:0002286 ! developmentally succeeded by is_a: RO:0002386 ! has potential to developmentally induce @@ -272331,7 +256138,7 @@ def: "Candidate definition: x developmentally related to y if and only if there comment: This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from property_value: editor_note "false" xsd:boolean property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "In general you should not use this relation to make assertions - use one of the more specific relations below this one" xsd:string domain: BFO:0000002 ! continuant range: BFO:0000002 ! continuant @@ -272364,7 +256171,7 @@ id: RO:0002286 name: developmentally succeeded by def: "Inverse of developmentally preceded by" [] property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: RO:0002384 ! has developmental potential involving [Typedef] @@ -272372,7 +256179,7 @@ id: RO:0002287 name: part of developmental precursor of property_value: IAO:0000112 "'hypopharyngeal eminence' SubClassOf 'part of precursor of' some tongue" xsd:string property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: part_of RO:0002210 is_a: RO:0002286 ! developmentally succeeded by @@ -272381,7 +256188,7 @@ id: RO:0002292 name: expresses def: "Inverse of 'expressed in'" [] property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: RO:0002330 ! genomically related to [Typedef] @@ -272389,7 +256196,7 @@ id: RO:0002314 name: characteristic of part of def: "q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w." [] property_value: editor_note "Because part_of is transitive, inheres in is a sub-relation of characteristic of part of" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "inheres in part of" xsd:string property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20064205 property_value: RO:0001900 RO:0001901 @@ -272402,14 +256209,14 @@ transitive_over: part_of ! part_of id: RO:0002320 name: evolutionarily related to def: "A relationship that holds via some environmental process" [] -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the process of evolution." xsd:string [Typedef] id: RO:0002323 name: mereotopologically related to def: "A mereological relationship or a topological relationship" [] -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships" xsd:string property_value: RO:0001900 RO:0001901 @@ -272417,7 +256224,7 @@ property_value: RO:0001900 RO:0001901 id: RO:0002324 name: developmentally related to def: "A relationship that holds between entities participating in some developmental process (GO:0032502)" [] -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development" xsd:string [Typedef] @@ -272426,7 +256233,7 @@ name: enables def: "c enables p iff c is capable of p and c acts to execute p." [] subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term property_value: IAO:0000112 "a particular instances of akt-2 enables some instance of protein kinase activity" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "catalyzes" xsd:string property_value: IAO:0000118 "executes" xsd:string property_value: IAO:0000118 "has" xsd:string @@ -272442,7 +256249,7 @@ transitive_over: RO:0002017 ! has component activity id: RO:0002329 name: part of structure that is capable of def: "this relation holds between c and p when c is part of some c', and c' is capable of p." [] -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "false" xsd:boolean holds_over_chain: part_of capable_of {http://purl.obolibrary.org/obo/RO_0002581="true"} is_a: functionally_related_to ! functionally related to @@ -272451,7 +256258,7 @@ is_a: functionally_related_to ! functionally related to id: RO:0002330 name: genomically related to def: "holds between two entities when some genome-level process such as gene expression is involved. This includes transcriptional, spliceosomal events. These relations can be used between either macromolecule entities (such as regions of nucleic acid) or between their abstract informational counterparts." [] -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving the genome of an organism" xsd:string domain: BFO:0000002 ! continuant range: BFO:0000002 ! continuant @@ -272460,7 +256267,7 @@ range: BFO:0000002 ! continuant id: RO:0002331 name: involved in def: "c involved_in p if and only if c enables some process p', and p' is part of p" [] -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "actively involved in" xsd:string property_value: IAO:0000118 "enables part of" xsd:string property_value: seeAlso Involved:in @@ -272474,7 +256281,7 @@ id: RO:0002333 name: enabled by def: "inverse of enables" [] subset: http://purl.obolibrary.org/obo/valid_for_gocam -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: functionally_related_to ! functionally related to is_a: has_participant ! has participant @@ -272482,7 +256289,7 @@ is_a: has_participant ! has participant id: RO:0002337 name: related via localization to def: "A relationship that holds via some process of localization" [] -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is a grouping relation." xsd:string domain: BFO:0000015 ! process range: BFO:0000002 ! continuant @@ -272502,14 +256309,14 @@ inverse_of: has_member ! has member [Typedef] id: RO:0002354 name: formed as result of -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: output_of ! output of [Typedef] id: RO:0002360 name: has dendrite location property_value: http://purl.org/dc/terms/source "http://neurolex.org/wiki/Property:DendriteLocation" xsd:anyURI -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: overlaps ! overlaps [Typedef] @@ -272517,7 +256324,7 @@ id: RO:0002375 name: in branching relationship with def: "A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network." [] property_value: IAO:0000114 IAO:0000428 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving branching relationships" xsd:string property_value: IAO:0000232 "This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (plant branches and roots, leaf veins, animal veins, arteries, nerves)" xsd:string property_value: RO:0004036 BFO:0000050 @@ -272532,7 +256339,7 @@ id: RO:0002379 name: spatially coextensive with def: "x spatially_coextensive_with y if and inly if x and y have the same location" [] property_value: IAO:0000112 "A lump of clay and a statue" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "This relation is added for formal completeness. It is unlikely to be used in many practical scenarios" xsd:string is_a: overlaps ! overlaps @@ -272541,7 +256348,7 @@ id: RO:0002384 name: has developmental potential involving def: "x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction)." [] property_value: IAO:0000114 IAO:0000428 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 domain: CARO:0000000 ! anatomical entity range: CARO:0000000 ! anatomical entity is_a: RO:0002324 ! developmentally related to @@ -272551,7 +256358,7 @@ id: RO:0002386 name: has potential to developmentally induce def: "x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y" [] property_value: IAO:0000114 IAO:0000428 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: RO:0002384 ! has developmental potential involving [Typedef] @@ -272559,14 +256366,14 @@ id: RO:0002388 name: has potential to directly develop into def: "x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y" [] property_value: IAO:0000114 IAO:0000428 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: has_potential_to_develop_into ! has potential to develop into [Typedef] id: RO:0002407 name: indirectly positively regulates def: "p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q." [] -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "indirectly activates" xsd:string property_value: RO:0002579 RO:0002213 holds_over_chain: directly_positively_regulates directly_positively_regulates @@ -272581,7 +256388,7 @@ transitive_over: directly_positively_regulates ! directly positively regulates id: RO:0002409 name: indirectly negatively regulates def: "p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q." [] -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "indirectly inhibits" xsd:string property_value: RO:0002579 RO:0002212 holds_over_chain: directly_negatively_regulates directly_negatively_regulates @@ -272596,14 +256403,14 @@ id: RO:0002410 name: causally related to def: "relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause." [https://en.wikipedia.org/wiki/Causality] property_value: editor_note "This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.\n\nTo define causal relations in an activity-flow type network, we make use of 3 primitives:\n\n * Temporal: how do the intervals of the two occurrents relate? \n * Is the causal relation regulatory?\n * Is the influence positive or negative?\n\nThe first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.\n\nFor the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.\n\nFor the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.\n\nEach of these 3 primitives can be composed to yield a cross-product of different relation types." xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string [Typedef] id: RO:0002428 name: involved in regulation of def: "c involved in regulation of p if c is involved in some p' and p' regulates some p" [] -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: RO:0002327 regulates holds_over_chain: RO:0002331 regulates is_a: RO:0002263 ! acts upstream of @@ -272613,7 +256420,7 @@ is_a: RO:0002431 ! involved in or involved in regulation of id: RO:0002429 name: involved in positive regulation of def: "c involved in regulation of p if c is involved in some p' and p' positively regulates some p" [] -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: RO:0004049 RO:0002428 holds_over_chain: RO:0002327 positively_regulates holds_over_chain: RO:0002331 positively_regulates @@ -272623,7 +256430,7 @@ is_a: RO:0002428 ! involved in regulation of id: RO:0002430 name: involved in negative regulation of def: "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p" [] -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: RO:0004050 RO:0002428 holds_over_chain: RO:0002327 negatively_regulates holds_over_chain: RO:0002331 negatively_regulates @@ -272634,7 +256441,7 @@ id: RO:0002431 name: involved in or involved in regulation of def: "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p" [] property_value: editor_note "OWL does not allow defining object properties via a Union" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "involved in or reguates" xsd:string is_a: functionally_related_to ! functionally related to is_a: RO:0002264 ! acts upstream of or within @@ -272646,7 +256453,7 @@ name: is active in def: "c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure." [GOC:cjm, GOC:dos] synonym: "enables activity in" EXACT [] property_value: IAO:0000112 "A protein that enables activity in a cytosol." xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "executes activity in" xsd:string holds_over_chain: RO:0002327 occurs_in {http://purl.obolibrary.org/obo/RO_0002581="true"} is_a: functionally_related_to ! functionally related to @@ -272661,7 +256468,7 @@ synonym: "in pairwise interaction with" EXACT [] property_value: closeMatch "http://purl.obolibrary.org/obo/MI_0914" xsd:anyURI property_value: editor_note "Considering relabeling as 'pairwise interacts with'" xsd:anyURI property_value: editor_note "This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact." xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules." xsd:string property_value: seeAlso "http://purl.obolibrary.org/obo/ro/docs/interaction-relations/" xsd:anyURI domain: BFO:0000040 ! material entity @@ -272673,7 +256480,7 @@ id: RO:0002436 name: molecularly interacts with def: "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other." [] property_value: closeMatch "http://purl.obolibrary.org/obo/MI_0915" xsd:anyURI -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "binds" xsd:string property_value: IAO:0000118 "molecularly binds with" xsd:string property_value: seeAlso ECO:0000353 @@ -272684,7 +256491,7 @@ is_a: RO:0002434 ! interacts with id: RO:0002447 name: phosphorylates property_value: editor_note "Axiomatization to GO to be added later" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y." xsd:string is_a: RO:0002436 ! molecularly interacts with @@ -272693,8 +256500,8 @@ id: RO:0002448 name: directly regulates activity of def: "The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.\n\nA and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B." [] synonym: "molecularly controls" EXACT [] -property_value: IAO:0000117 "Chris Mungall" xsd:string -property_value: IAO:0000117 "Vasundra Touré" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431 domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_a: RO:0002436 ! molecularly interacts with @@ -272705,8 +256512,8 @@ id: RO:0002449 name: directly negatively regulates activity of def: "The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B." [] synonym: "molecularly decreases activity of" EXACT [] -property_value: IAO:0000117 "Chris Mungall" xsd:string -property_value: IAO:0000117 "Vasundra Touré" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431 property_value: IAO:0000118 "directly inhibits" xsd:string domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity @@ -272717,8 +256524,8 @@ id: RO:0002450 name: directly positively regulates activity of def: "The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B." [] synonym: "molecularly increases activity of" EXACT [] -property_value: IAO:0000117 "Chris Mungall" xsd:string -property_value: IAO:0000117 "Vasundra Touré" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431 property_value: IAO:0000118 "directly activates" xsd:string domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity @@ -272727,7 +256534,7 @@ is_a: RO:0002448 ! directly regulates activity of [Typedef] id: RO:0002464 name: helper property (not for use in curation) -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning." xsd:string [Typedef] @@ -272735,7 +256542,7 @@ id: RO:0002479 name: has part that occurs in def: "p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c." [] subset: ro-eco -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 domain: BFO:0000003 ! occurrent range: BFO:0000004 ! independent continuant holds_over_chain: has_part occurs_in {http://purl.obolibrary.org/obo/RO_0002581="true"} @@ -272743,14 +256550,14 @@ holds_over_chain: has_part occurs_in {http://purl.obolibrary.org/obo/RO_0002581= [Typedef] id: RO:0002481 name: is kinase activity -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: RO:0002564 ! molecular interaction relation helper property [Typedef] id: RO:0002485 name: receives input from property_value: editor_note "See notes for inverse relation" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: connected_to ! connected to inverse_of: RO:0002486 ! sends output to @@ -272758,13 +256565,13 @@ inverse_of: RO:0002486 ! sends output to id: RO:0002486 name: sends output to property_value: editor_note "This is an exploratory relation. The label is taken from the FMA. It needs aligned with the neuron-specific relations such as has postsynaptic terminal in." xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: connected_to ! connected to [Typedef] id: RO:0002487 name: relation between physical entity and a process or stage -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, typically connecting an anatomical entity to a biological process or developmental stage." xsd:string domain: BFO:0000004 ! independent continuant range: BFO:0000003 ! occurrent @@ -272774,7 +256581,7 @@ id: RO:0002490 name: existence overlaps def: "x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y))" [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: RO:0002487 ! relation between physical entity and a process or stage [Typedef] @@ -272789,7 +256596,7 @@ inverse_of: process_has_causal_agent ! process has causal agent id: RO:0002501 name: causal relation between processes def: "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q." [] -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string domain: BFO:0000003 ! occurrent @@ -272799,14 +256606,14 @@ is_a: RO:0002410 ! causally related to [Typedef] id: RO:0002502 name: depends on -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: seeAlso BFO:0000169 [Typedef] id: RO:0002506 name: causal relation between entities property_value: editor_note "The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string domain: BFO:0000002 ! continuant @@ -272816,7 +256623,7 @@ is_a: RO:0002410 ! causally related to [Typedef] id: RO:0002559 name: causally influenced by -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "causally influenced by (entity-centric)" xsd:string is_a: RO:0002506 ! causal relation between entities @@ -272825,7 +256632,7 @@ inverse_of: RO:0002566 ! causally influences [Typedef] id: RO:0002563 name: interaction relation helper property -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: seeAlso http://ontologydesignpatterns.org/wiki/Submissions:N-Ary_Relation_Pattern_%28OWL_2%29 property_value: seeAlso "http://purl.obolibrary.org/obo/ro/docs/interaction-relations/" xsd:anyURI is_a: RO:0002464 ! helper property (not for use in curation) @@ -272833,15 +256640,15 @@ is_a: RO:0002464 ! helper property (not for use in curation) [Typedef] id: RO:0002564 name: molecular interaction relation helper property -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: RO:0002563 ! interaction relation helper property [Typedef] id: RO:0002566 name: causally influences def: "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size)." [] -property_value: IAO:0000117 "Chris Mungall" xsd:string -property_value: IAO:0000117 "Vasundra Touré" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "causally influences (entity-centric)" xsd:string domain: BFO:0000002 ! continuant @@ -272852,7 +256659,7 @@ is_a: RO:0002506 ! causal relation between entities id: RO:0002567 name: biomechanically related to def: "A relation that holds between elements of a musculoskeletal system or its analogs." [] -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the biomechanical processes." xsd:string domain: CARO:0000003 ! connected anatomical structure range: CARO:0000003 ! connected anatomical structure @@ -272863,7 +256670,7 @@ id: RO:0002584 name: has part structure that is capable of def: "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p" [] property_value: IAO:0000112 "gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: has_part capable_of is_a: functionally_related_to ! functionally related to is_a: RO:0002595 ! causal relation between material entity and a process @@ -272879,7 +256686,7 @@ id: RO:0002595 name: causal relation between material entity and a process def: "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity." [] property_value: editor_note "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations domain: BFO:0000040 ! material entity range: BFO:0000015 ! process @@ -272917,7 +256724,7 @@ name: enables subfunction def: "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P." [] holds_over_chain: RO:0002327 has_part is_a: functionally_related_to ! functionally related to -created_by: cjm +created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-01-25T23:20:13Z [Typedef] @@ -272928,7 +256735,7 @@ property_value: RO:0004049 RO:0002264 property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within,_positive_effect holds_over_chain: RO:0002327 RO:0004047 is_a: RO:0002264 ! acts upstream of or within -created_by: cjm +created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-01-26T23:49:30Z [Typedef] @@ -272938,7 +256745,7 @@ subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term property_value: RO:0004050 RO:0002264 holds_over_chain: RO:0002327 RO:0004046 is_a: RO:0002264 ! acts upstream of or within -created_by: cjm +created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-01-26T23:49:51Z [Typedef] @@ -272951,7 +256758,7 @@ property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of, holds_over_chain: RO:0002327 causally_upstream_of,_positive_effect is_a: RO:0002263 ! acts upstream of is_a: RO:0004032 ! acts upstream of or within, positive effect -created_by: cjm +created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-01-26T23:53:14Z [Typedef] @@ -272964,7 +256771,7 @@ property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of, holds_over_chain: RO:0002327 causally_upstream_of,_negative_effect is_a: RO:0002263 ! acts upstream of is_a: RO:0004033 ! acts upstream of or within, negative effect -created_by: cjm +created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-01-26T23:53:22Z [Typedef] @@ -272972,7 +256779,7 @@ id: RO:0004046 name: causally upstream of or within, negative effect property_value: RO:0004050 RO:0002418 is_a: causally_upstream_of_or_within ! causally upstream of or within -created_by: cjm +created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-03-13T23:55:05Z [Typedef] @@ -272980,14 +256787,14 @@ id: RO:0004047 name: causally upstream of or within, positive effect property_value: RO:0004049 RO:0002418 is_a: causally_upstream_of_or_within ! causally upstream of or within -created_by: cjm +created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-03-13T23:55:19Z [Typedef] id: RO:0011002 name: regulates activity of def: "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B." [] -property_value: IAO:0000117 "Vasundra Touré" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431 domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_a: RO:0002566 ! causally influences @@ -273093,8 +256900,8 @@ name: device utilizes material def: "X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y." [] synonym: "utilizes" BROAD [] property_value: IAO:0000112 "A diagnostic testing device utilizes a specimen." xsd:string -property_value: IAO:0000117 "https://orcid.org/0000-0001-9625-1899" xsd:string -property_value: IAO:0000117 "https://orcid.org/0000-0003-2620-0345" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0001-9625-1899 +property_value: IAO:0000117 https://orcid.org/0000-0003-2620-0345 property_value: IAO:0000232 "A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input." xsd:string property_value: IAO:0000232 "See github ticket https://github.com/oborel/obo-relations/issues/497" xsd:string holds_over_chain: capable_of has_input @@ -273129,7 +256936,7 @@ property_value: IAO:0000112 "The epidermis layer of a vertebrate is adjacent to property_value: IAO:0000112 "The plasma membrane of a cell is adjacent to the cytoplasm, and also to the cell lumen which the cytoplasm occupies." xsd:string property_value: IAO:0000112 "The skin of the forelimb is adjacent to the skin of the torso if these are considered anatomical subdivisions with a defined border. Otherwise a relation such as continuous_with would be used." xsd:string property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: RO:0001900 RO:0001901 domain: BFO:0000004 ! independent continuant range: BFO:0000004 ! independent continuant @@ -273157,7 +256964,7 @@ namespace: uberon def: "a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a" [] subset: ro-eco xref: RO:0002371 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000589 "attached to (anatomical structure to anatomical structure)" xsd:string is_symmetric: true is_a: attaches_to_part_of ! attached to part of @@ -273202,7 +257009,7 @@ def: "X outer_layer_of Y iff:\n. X :continuant that bearer_of some PATO:laminar\ comment: A relationship that applies between a continuant and its outer, bounding layer. Examples include the relationship between a multicellular organism and its integument, between an animal cell and its plasma membrane, and between a membrane bound organelle and its outer/bounding membrane. subset: ro-eco xref: RO:0002007 -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 range: BFO:0000040 ! material entity is_a: part_of ! part_of @@ -273214,7 +257021,7 @@ def: "x is a branching part of y if and only if x is part of y and x is connecte subset: ro-eco xref: RO:0002380 property_value: IAO:0000112 "In the tree T depicted in https://oborel.github.io/obo-relations/branching_part_of.png, B1 is a (direct) branching part of T. B1-1, B1-2, and B1-3 are also branching parts of T, but these are considered indirect branching parts as they do not directly connect to the main stem S" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: seeAlso "FMA:85994" xsd:string property_value: seeAlso https://github.com/obophenotype/uberon/issues/2212 is_a: part_of ! part_of @@ -273231,7 +257038,7 @@ subset: ro-eco xref: RO:0002215 property_value: IAO:0000112 "mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)" xsd:string property_value: IAO:0000112 "osteoclast SubClassOf 'capable of' some 'bone resorption'" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "has function realized in" xsd:string property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20123131 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/21208450 @@ -273247,7 +257054,7 @@ namespace: external namespace: uberon def: "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p." [] xref: RO:0002216 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "has function in" xsd:string property_value: seeAlso http://purl.obolibrary.org/obo/ro/docs/reflexivity/ holds_over_chain: capable_of part_of {http://purl.obolibrary.org/obo/RO_0002582="true"} @@ -273261,7 +257068,7 @@ namespace: external def: "inverse of upstream of" [] xref: RO:0002404 property_value: IAO:0000114 IAO:0000428 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: causally_downstream_of_or_within ! causally downstream of or within is_a: preceded_by ! preceded by inverse_of: causally_upstream_of ! causally upstream of @@ -273273,7 +257080,7 @@ namespace: external def: "inverse of causally upstream of or within" [] subset: RO:0002259 xref: RO:0002427 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations is_transitive: true is_a: RO:0002501 ! causal relation between processes @@ -273286,7 +257093,7 @@ def: "p is causally upstream of q iff p is causally related to q, the end of p p subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002411 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_transitive: true is_a: causally_upstream_of_or_within ! causally upstream of or within is_a: precedes ! precedes @@ -273299,7 +257106,7 @@ def: "p is causally upstream of, negative effect q iff p is casually upstream of subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002305 -property_value: http://purl.org/dc/terms/creator "cjm" xsd:string +property_value: http://purl.org/dc/terms/creator https://orcid.org/0000-0002-6601-2165 property_value: RO:0004050 RO:0002411 is_a: causally_upstream_of ! causally upstream of is_a: RO:0004046 ! causally upstream of or within, negative effect @@ -273313,7 +257120,7 @@ comment: holds between x and y if and only if x is causally upstream of y and th subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002304 -property_value: http://purl.org/dc/terms/creator "cjm" xsd:string +property_value: http://purl.org/dc/terms/creator https://orcid.org/0000-0002-6601-2165 property_value: RO:0004049 RO:0002411 is_a: causally_upstream_of ! causally upstream of is_a: RO:0004047 ! causally upstream of or within, positive effect @@ -273326,7 +257133,7 @@ def: "p is 'causally upstream or within' q iff p is causally related to q, and t synonym: "affects" RELATED [] xref: RO:0002418 property_value: editor_note "We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "influences (processual)" xsd:string is_transitive: true is_a: RO:0002501 ! causal relation between processes @@ -273360,7 +257167,7 @@ def: "x composed_primarily_of y if and only if more than half of the mass of x i subset: ro-eco xref: RO:0002473 property_value: IAO:0000112 "'otolith organ' SubClassOf 'composed primarily of' some 'calcium carbonate'" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/22293552 property_value: RO:0001900 RO:0001901 domain: BFO:0000040 ! material entity @@ -273425,7 +257232,7 @@ namespace: uberon def: "X continuous_with Y if and only if X and Y share a fiat boundary." [] xref: RO:0002150 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000118 "connected to" xsd:string property_value: IAO:0000232 "The label for this relation was previously connected to. I relabeled this to \"continuous with\". The standard notion of connectedness does not imply shared boundaries - e.g. Glasgow connected_to Edinburgh via M8; my patella connected_to my femur (via patellar-femoral joint)" xsd:string property_value: RO:0001900 RO:0001901 @@ -273441,7 +257248,7 @@ name: contributes to morphology of namespace: uberon def: "p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm." [] xref: RO:0002433 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: overlaps ! overlaps [Typedef] @@ -273506,9 +257313,9 @@ namespace: uberon def: "t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor material anatomical entity type T to T', where T' develops_from T" [] xref: RO:0002256 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string -property_value: IAO:0000117 "Melissa Haendel" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0001-9114-8737 +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000118 "induced by" xsd:string property_value: IAO:0000119 " Developmental Biology, Gilbert, 8th edition, figure 6.5(F)" xsd:string property_value: IAO:0000119 "GO:0001759" xsd:string @@ -273527,7 +257334,7 @@ def: "x developmentally replaces y if and only if there is some developmental pr xref: RO:0002285 property_value: editor_note "This relation is intended for cases such as when we have a bone element replacing its cartilage element precursor. Currently most AOs represent this using 'develops from'. We need to decide whether 'develops from' will be generic and encompass replacement, or whether we need a new name for a generic relation that encompasses replacement and development-via-cell-lineage" xsd:string property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "replaces" xsd:string is_a: RO:0002258 ! developmentally preceded by @@ -273539,10 +257346,10 @@ def: "x develops from y if and only if either (a) x directly develops from y or comment: This is the transitive form of the develops from relation xref: RO:0002202 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string -property_value: IAO:0000117 "Melissa Haendel" xsd:string -property_value: IAO:0000117 "Terry Meehan" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0001-9114-8737 +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 +property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 domain: BFO:0000004 ! independent continuant range: BFO:0000004 ! independent continuant is_transitive: true @@ -273557,7 +257364,7 @@ namespace: uberon def: "x develops from part of y if and only if there exists some z such that x develops from z and z is part of y" [] xref: RO:0002225 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: directly_develops_from part_of is_a: develops_from ! develops from @@ -273568,7 +257375,7 @@ namespace: uberon def: "x develops_in y if x is located in y whilst x is developing" [] xref: RO:0002226 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "EHDAA2" xsd:string property_value: IAO:0000119 "Jonathan Bard, EHDAA2" xsd:string domain: CARO:0000000 ! anatomical entity @@ -273581,11 +257388,11 @@ name: directly develops from namespace: uberon def: "Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y." [] comment: TODO - add child relations from DOS +synonym: "has developmental precursor" EXACT [] xref: RO:0002207 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string -property_value: IAO:0000117 "has developmental precursor" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000119 "FBbt" xsd:string property_value: RO:0002575 RO:0002202 is_a: develops_from ! develops from @@ -273630,7 +257437,7 @@ subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002578 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "directly regulates (processual)" xsd:string property_value: RO:0002575 RO:0002211 @@ -273692,6 +257499,7 @@ subset: ro-eco xref: RO:0002229 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: part_of ! part_of is_a: RO:0002222 ! temporally related to inverse_of: ends_with ! ends with @@ -273706,6 +257514,7 @@ subset: ro-eco xref: RO:0002230 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "finished by" xsd:string is_transitive: true is_a: has_part ! has part @@ -273720,7 +257529,7 @@ def: "x existence ends during y if and only if the time point at which x ends is comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. synonym: "ceases_to_exist_during" EXACT [] xref: RO:0002492 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: existence_ends_during_or_before ! existence ends during or before is_a: RO:0002490 ! existence overlaps transitive_over: part_of ! part_of @@ -273732,7 +257541,7 @@ namespace: uberon def: "x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends." [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. xref: RO:0002497 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: part_of existence_ends_during_or_before holds_over_chain: RO:0002286 existence_ends_during_or_before is_a: RO:0002487 ! relation between physical entity and a process or stage @@ -273747,7 +257556,7 @@ namespace: uberon def: "x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y)." [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. xref: RO:0002493 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: existence_ends_during ! existence ends during [Typedef] @@ -273758,7 +257567,7 @@ def: "x exists during y if and only if: 1) the time point at which x begins to e comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. synonym: "exists during" EXACT [] xref: RO:0002491 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: existence_ends_during ! existence ends during is_a: existence_starts_during ! existence starts during @@ -273768,7 +257577,7 @@ name: existence starts during namespace: uberon def: "x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y)." [] xref: RO:0002488 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: existence_starts_during_or_after ! existence starts during or after is_a: RO:0002490 ! existence overlaps transitive_over: part_of ! part_of @@ -273780,7 +257589,7 @@ namespace: uberon def: "x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y)." [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. xref: RO:0002496 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: part_of existence_starts_during_or_after holds_over_chain: RO:0002258 existence_starts_during_or_after is_a: RO:0002487 ! relation between physical entity and a process or stage @@ -273794,7 +257603,7 @@ name: existence starts with namespace: uberon def: "x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y)." [] xref: RO:0002489 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: existence_starts_during ! existence starts during [Typedef] @@ -273819,7 +257628,7 @@ name: functionally related to namespace: uberon def: "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities." [] xref: RO:0002328 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "This is a grouping relation that collects relations used for the purpose of connecting structure and function" xsd:string [Typedef] @@ -273832,7 +257641,7 @@ xref: RO:0002002 property_value: editor_note "A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts." xsd:string property_value: editor_note "Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape." xsd:string property_value: IAO:0000112 "my body has 2D boundary the surface of my skin" xsd:string -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000118 "has boundary" xsd:string property_value: IAO:0000118 "has_2D_boundary" xsd:string property_value: RO:0001900 RO:0001901 @@ -273850,7 +257659,7 @@ def: "inverse of branching part of" [] subset: ro-eco subset: RO:0002259 xref: RO:0002569 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_transitive: true is_a: has_part ! has part is_a: RO:0002375 ! in branching relationship with @@ -273878,7 +257687,7 @@ def: "x has developmental contribution from y iff x has some part z such that z xref: RO:0002254 property_value: IAO:0000112 "Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]" xsd:string property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 domain: CARO:0000000 ! anatomical entity range: CARO:0000000 ! anatomical entity holds_over_chain: has_part develops_from @@ -273893,7 +257702,7 @@ def: "x 'has end location' y if and only if there exists some process z such tha subset: ro-eco xref: RO:0002232 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "ends with process that occurs in" xsd:string domain: BFO:0000015 ! process range: BFO:0000004 ! independent continuant @@ -273919,7 +257728,7 @@ subset: http://purl.obolibrary.org/obo/valid_for_gocam subset: ro-eco xref: RO:0002233 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "consumes" xsd:string domain: BFO:0000015 ! process holds_over_chain: starts_with has_input @@ -273950,7 +257759,7 @@ name: has muscle antagonist namespace: uberon def: "m1 has_muscle_antagonist m2 iff m1 has_muscle_insertion s, m2 has_muscle_insection s, m1 acts in opposition to m2, and m2 is responsible for returning the structure to its initial position." [] xref: RO:0002568 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "Wikipedia:Antagonist_(muscle)" xsd:string is_a: RO:0002567 ! biomechanically related to @@ -273960,7 +257769,7 @@ name: has muscle insertion namespace: uberon def: "m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone." [] xref: RO:0002373 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "Wikipedia:Insertion_(anatomy)" xsd:string property_value: seeAlso http://dbpedia.org/property/insertion domain: CARO:0000003 {http://purl.obolibrary.org/obo/IAO_0000116="We need to import uberon muscle into RO to use as a stricter domain constraint"} ! connected anatomical structure @@ -273973,7 +257782,7 @@ name: has muscle origin namespace: uberon def: "m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to." [] xref: RO:0002372 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "Wikipedia:Insertion_(anatomy)" xsd:string property_value: seeAlso http://dbpedia.org/property/origin domain: CARO:0000003 {comment="We need to import uberon muscle to create a stricter domain constraint"} ! connected anatomical structure @@ -273992,10 +257801,6 @@ is_a: negatively_regulated_by ! negatively regulated by created_by: dos creation_date: 2017-05-24T09:31:01Z -[Typedef] -id: has_not_completed -name: has_not_completed - [Typedef] id: has_ontology_root_term name: has ontology root term @@ -274015,7 +257820,7 @@ subset: http://purl.obolibrary.org/obo/valid_for_gocam subset: ro-eco xref: RO:0002234 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "produces" xsd:string holds_over_chain: ends_with has_output is_a: has_participant ! has participant @@ -274069,7 +257874,7 @@ namespace: uberon def: "x has the potential to develop into y iff x develops into y or if x is capable of developing into y" [] xref: RO:0002387 property_value: IAO:0000114 IAO:0000428 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: RO:0002384 ! has developmental potential involving [Typedef] @@ -274079,7 +257884,7 @@ namespace: uberon def: "x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y" [] xref: RO:0002385 property_value: IAO:0000114 IAO:0000428 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: RO:0002384 ! has developmental potential involving [Typedef] @@ -274091,7 +257896,7 @@ subset: http://purl.obolibrary.org/obo/valid_for_go_ontology xref: RO:0004009 is_a: has_input ! has input is_a: has_primary_input_or_output ! has primary input or output -created_by: cjm +created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-12-13T11:26:56Z [Typedef] @@ -274102,7 +257907,7 @@ def: "p 'has primary input ot output' c iff either (a) p 'has primary input' c o subset: http://purl.obolibrary.org/obo/valid_for_go_ontology xref: RO:0004007 is_a: has_participant ! has participant -created_by: cjm +created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-12-13T11:26:17Z [Typedef] @@ -274114,7 +257919,7 @@ subset: http://purl.obolibrary.org/obo/valid_for_go_ontology xref: RO:0004008 is_a: has_output ! has output is_a: has_primary_input_or_output ! has primary input or output -created_by: cjm +created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-12-13T11:26:32Z [Typedef] @@ -274147,7 +257952,7 @@ namespace: uberon def: "A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision." [] xref: RO:0002551 property_value: IAO:0000112 "Forelimb SubClassOf has_skeleton some 'Forelimb skeleton'" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "has supporting framework" xsd:string property_value: IAO:0000232 "The skeleton of a structure may be a true skeleton (for example, the bony skeleton of a hand) or any kind of support framework (the hydrostatic skeleton of a sea star, the exoskeleton of an insect, the cytoskeleton of a cell)." xsd:string domain: CARO:0000003 ! connected anatomical structure @@ -274166,7 +257971,7 @@ def: "x 'has starts location' y if and only if there exists some process z such subset: ro-eco xref: RO:0002231 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "starts with process that occurs in" xsd:string domain: BFO:0000015 ! process range: BFO:0000004 ! independent continuant @@ -274182,7 +257987,7 @@ subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002339 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: results_in_transport_to_from_or_in ! results in transport to from or in transitive_over: part_of ! part_of @@ -274195,7 +258000,7 @@ subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002338 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: results_in_transport_to_from_or_in ! results in transport to from or in transitive_over: part_of ! part_of @@ -274218,7 +258023,7 @@ name: immediate transformation of namespace: uberon def: "x immediate transformation of y iff x immediately succeeds y temporally at a time boundary t, and all of the matter present in x at t is present in y at t, and all the matter in y at t is present in x at t" [] xref: RO:0002495 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: RO:0002575 RO:0002494 is_a: directly_develops_from ! directly develops from is_a: transformation_of ! transformation of @@ -274229,7 +258034,7 @@ name: immediately causally downstream of namespace: external xref: RO:0002405 property_value: IAO:0000114 IAO:0000428 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: causally_downstream_of ! causally downstream of is_a: immediately_preceded_by ! immediately preceded by inverse_of: immediately_causally_upstream_of ! immediately causally upstream of @@ -274240,7 +258045,7 @@ name: immediately causally upstream of namespace: external def: "p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q." [] xref: RO:0002412 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: RO:0002575 RO:0002411 is_a: causally_upstream_of ! causally upstream of is_a: immediately_precedes ! immediately precedes @@ -274272,6 +258077,7 @@ comment: X immediately_precedes_Y iff: end(X) simultaneous_with start(Y) subset: ro-eco xref: RO:0002090 property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000118 "ends_at_start_of" xsd:string property_value: IAO:0000118 "meets" xsd:string property_value: RO:0002575 BFO:0000063 @@ -274347,12 +258153,12 @@ comment: Connects a biological entity to its taxon of origin. subset: ro-eco xref: RO:0002162 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string -property_value: IAO:0000117 "Jennifer Deegan" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0001-9227-417X +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/17921072 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20973947 property_value: seeAlso https://github.com/obophenotype/uberon/wiki/Taxon-constraints -range: CARO:0001010 ! organism or virus or viroid +range: CARO:0001010 ! organism holds_over_chain: attaches_to in_taxon holds_over_chain: capable_of in_taxon holds_over_chain: connected_to in_taxon @@ -274393,7 +258199,7 @@ name: innervated_by namespace: uberon xref: RO:0002005 property_value: http://purl.org/spar/cito/citesAsAuthority "http://www.ncbi.nlm.nih.gov/pubmed/22402613" xsd:anyURI -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 domain: CARO:0000003 ! connected anatomical structure range: CARO:0001001 ! neuron projection bundle inverse_of: innervates ! innervates @@ -274405,11 +258211,11 @@ name: innervates namespace: fly_anatomy.ontology namespace: uberon def: "Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input.\nT innervates some R\nExpands_to: T has_fasciculating_neuron_projection that synapse_in some R." [] -def: "Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R." [FBC:DOS] +def: "Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R." [https://orcid.org/0000-0002-7073-9172] xref: RO:0002134 property_value: http://purl.org/spar/cito/citesAsAuthority http://www.ncbi.nlm.nih.gov/pubmed/22402613 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: RO:0001900 RO:0001901 domain: CARO:0001001 ! neuron projection bundle transitive_over: part_of ! part_of @@ -274424,7 +258230,7 @@ def: "inverse of has input" [] subset: ro-eco subset: RO:0002259 xref: RO:0002352 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: functionally_related_to ! functionally related to is_a: participates_in ! participates in @@ -274434,16 +258240,6 @@ name: intersects midsagittal plane of namespace: uberon xref: BSPO:0005001 -[Typedef] -id: lacks_part -name: lacks_part -expand_expression_to: "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y" [] - -[Typedef] -id: lacks_plasma_membrane_part -name: lacks_plasma_membrane_part -expand_expression_to: "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)" [] - [Typedef] id: layer_part_of name: layer part of @@ -274492,7 +258288,7 @@ namespace: uberon def: "x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull." [] subset: ro-eco xref: RO:0002571 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "GOC:cjm" xsd:string range: BFO:0000040 ! material entity is_a: part_of ! part_of @@ -274504,7 +258300,7 @@ namespace: uberon def: "s is luminal space of x iff s is lumen_of x and s is an immaterial entity" [] subset: ro-eco xref: RO:0002572 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 domain: BFO:0000141 ! immaterial entity is_a: lumen_of ! lumen of @@ -274515,7 +258311,7 @@ namespace: external def: "inverse of negatively regulates" [] subset: RO:0002259 xref: RO:0002335 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: regulated_by ! regulated by [Typedef] @@ -274528,7 +258324,7 @@ subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002212 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "negatively regulates (process to process)" xsd:string property_value: RO:0004050 RO:0002211 @@ -274557,7 +258353,7 @@ def: "S never_in_taxon T iff: S SubClassOf in_taxon only not T." [PMID:20973947] def: "x never in taxon T if and only if T is a class, and x does not instantiate the class expression \"in taxon some T\". Note that this is a shortcut relation, and should be used as a hasValue restriction in OWL." [] xref: RO:0002161 property_value: IAO:0000112 "tooth SubClassOf 'never in taxon' value 'Aves'" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/17921072 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20973947 property_value: OMO:0002000 "PREFIX rdfs: \nPREFIX owl: \nPREFIX in_taxon: \nPREFIX never_in_taxon: \nCONSTRUCT {\n in_taxon: a owl:ObjectProperty .\n ?x owl:disjointWith [\n a owl:Restriction ;\n owl:onProperty in_taxon: ;\n owl:someValuesFrom ?taxon\n ] .\n ?x rdfs:subClassOf [\n a owl:Restriction ;\n owl:onProperty in_taxon: ;\n owl:someValuesFrom [\n a owl:Class ;\n owl:complementOf ?taxon\n ]\n ] .\n}\nWHERE {\n ?x never_in_taxon: ?taxon .\n}" xsd:string @@ -274598,7 +258394,7 @@ xref: RO:0002160 property_value: editor_note "The original intent was to treat this as a macro that expands to 'in taxon' only ?Y - however, this is not necessary if we instead have supplemental axioms that state that each pair of sibling tax have a disjointness axiom using the 'in taxon' property - e.g.\n\n 'in taxon' some Eukaryota DisjointWith 'in taxon' some Eubacteria" xsd:string property_value: IAO:0000112 "lactation SubClassOf 'only in taxon' some 'Mammalia'" xsd:string property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/17921072 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20973947 property_value: seeAlso https://github.com/obophenotype/uberon/wiki/Taxon-constraints @@ -274613,7 +258409,7 @@ def: "inverse of has output" [] subset: ro-eco subset: RO:0002259 xref: RO:0002353 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: functionally_related_to ! functionally related to is_a: participates_in ! participates in @@ -274696,7 +258492,7 @@ namespace: external def: "inverse of positively regulates" [] subset: RO:0002259 xref: RO:0002336 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: regulated_by ! regulated by [Typedef] @@ -274709,7 +258505,7 @@ subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002213 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "positively regulates (process to process)" xsd:string property_value: RO:0004049 RO:0002211 @@ -274801,7 +258597,7 @@ def: "S present_in_taxon T if some instance of T has some S. This does not means comment: The SPARQL expansion for this relation introduces new named classes into the ontology. For this reason it is likely that the expansion should only be performed during a QC pipeline; the expanded output should usually not be included in a published version of the ontology. synonym: "applicable for taxon" EXACT [] xref: RO:0002175 -property_value: IAO:0000117 "https://orcid.org/0000-0002-6601-2165" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/22293552 property_value: OMO:0002000 "PREFIX rdfs: \nPREFIX owl: \nPREFIX in_taxon: \nPREFIX present_in_taxon: \nCONSTRUCT {\n in_taxon: a owl:ObjectProperty .\n ?witness rdfs:label ?label .\n ?witness rdfs:subClassOf ?x .\n ?witness rdfs:subClassOf [\n a owl:Restriction ;\n owl:onProperty in_taxon: ;\n owl:someValuesFrom ?taxon\n ] .\n}\nWHERE {\n ?x present_in_taxon: ?taxon .\n BIND(IRI(CONCAT(\n \"http://purl.obolibrary.org/obo/RO_0002175#\",\n MD5(STR(?x)),\n \"-\",\n MD5(STR(?taxon))\n )) as ?witness)\n BIND(CONCAT(STR(?x), \" in taxon \", STR(?taxon)) AS ?label)\n}" xsd:string property_value: seeAlso https://github.com/obophenotype/uberon/wiki/Taxon-constraints @@ -274826,7 +258622,7 @@ def: "a produced_by b iff some process that occurs_in b has_output a." [] subset: ro-eco xref: RO:0003001 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Melissa Haendel" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0001-9114-8737 domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity @@ -274840,7 +258636,7 @@ comment: Note that this definition doesn't quite distinguish the output of a tra subset: ro-eco xref: RO:0003000 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Melissa Haendel" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0001-9114-8737 domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity inverse_of: produced_by ! produced by @@ -274878,7 +258674,7 @@ namespace: external def: "inverse of regulates" [] subset: RO:0002259 xref: RO:0002334 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000589 "regulated by (processual)" xsd:string domain: BFO:0000015 ! process range: BFO:0000015 ! process @@ -274895,9 +258691,9 @@ subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002211 -property_value: IAO:0000117 "Chris Mungall" xsd:string -property_value: IAO:0000117 "David Hill" xsd:string -property_value: IAO:0000117 "Tanya Berardini" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0001-7476-6306 +property_value: IAO:0000117 https://orcid.org/0000-0002-3837-8864 +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "GO" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000232 "Regulation precludes parthood; the regulatory process may not be within the regulated process." xsd:string @@ -274931,7 +258727,7 @@ namespace: external def: "p regulates levels of c if p regulates some amount (PATO:0000070) of c" [] xref: RO:0002332 property_value: IAO:0000112 "every cellular sphingolipid homeostasis process regulates_level_of some sphingolipid" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "regulates levels of (process to entity)" xsd:string domain: BFO:0000015 ! process @@ -274948,7 +258744,7 @@ subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002315 property_value: IAO:0000112 "an annotation of gene X to cell differentiation with results_in_maturation_of CL:0000057 (fibroblast) means that at the end of the process the input cell that did not have features of a fibroblast, now has the features of a fibroblast." xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "GOC:mtg_berkeley_2013" xsd:string range: CARO:0000003 ! connected anatomical structure is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure @@ -274972,7 +258768,7 @@ namespace: external def: "p has anatomical participant c iff p has participant c, and c is an anatomical entity" [] xref: RO:0040036 is_a: has_participant ! has participant -created_by: cjm +created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-09-26T01:08:58Z [Typedef] @@ -274986,7 +258782,7 @@ subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002296 property_value: IAO:0000112 "every flower development (GO:0009908) results in development of some flower (PO:0009046)" xsd:string property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "http://www.geneontology.org/GO.doc.development.shtml" xsd:anyURI is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure is_a: results_in_developmental_progression_of ! results in developmental progression of @@ -274999,7 +258795,7 @@ def: "p results in the developmental progression of s iff p is a developmental p xref: RO:0002295 property_value: editor_note "This property and its subproperties are being used primarily for the definition of GO developmental processes. The property hierarchy mirrors the core GO hierarchy. In future we may be able to make do with a more minimal set of properties, but due to the way GO is currently structured we require highly specific relations to avoid incorrect entailments. To avoid this, the corresponding genus terms in GO should be declared mutually disjoint." xsd:string property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: seeAlso Ontology:extensions domain: GO:0008150 ! biological_process range: CARO:0000000 ! anatomical entity @@ -275039,7 +258835,7 @@ xref: RO:0002297 property_value: IAO:0000112 "an annotation of gene X to anatomical structure formation with results_in_formation_of UBERON:0000007 (pituitary gland) means that at the beginning of the process a pituitary gland does not exist and at the end of the process a pituitary gland exists." xsd:string property_value: IAO:0000112 "every \"endocardial cushion formation\" (GO:0003272) results_in_formation_of some \"endocardial cushion\" (UBERON:0002062)" xsd:string property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "GOC:mtg_berkeley_2013" xsd:string is_a: has_output ! has output is_a: results_in_developmental_progression_of ! results in developmental progression of @@ -275063,7 +258859,7 @@ name: results in growth of namespace: external xref: RO:0002343 property_value: IAO:0000112 "'pollen tube growth' results_in growth_of some 'pollen tube'" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure is_a: results_in_developmental_progression_of ! results in developmental progression of @@ -275079,7 +258875,7 @@ xref: RO:0002299 property_value: IAO:0000112 " an annotation of gene X to cell maturation with results_in_maturation_of CL:0000057 (fibroblast) means that the fibroblast is mature at the end of the process" xsd:string property_value: IAO:0000112 "bone maturation (GO:0070977) results_in_maturation_of bone (UBERON:0001474)" xsd:string property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "GOC:mtg_berkeley_2013" xsd:string is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure is_a: results_in_developmental_progression_of ! results in developmental progression of @@ -275096,7 +258892,7 @@ xref: RO:0002298 property_value: IAO:0000112 "an annotation of gene X to cell morphogenesis with results_in_morphogenesis_of CL:0000540 (neuron) means that at the end of the process an input neuron has attained its shape." xsd:string property_value: IAO:0000112 "tongue morphogenesis (GO:0043587) results in morphogenesis of tongue (UBERON:0001723)" xsd:string property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "GOC:mtg_berkeley_2013" xsd:string is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure is_a: results_in_developmental_progression_of ! results in developmental progression of @@ -275110,7 +258906,7 @@ subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002565 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "" xsd:string is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure @@ -275130,7 +258926,7 @@ namespace: external def: "Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m." [] subset: http://purl.obolibrary.org/obo/valid_for_go_ontology xref: RO:0002342 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: results_in_transport_to_from_or_in ! results in transport to from or in is_a: RO:0002021 ! occurs across @@ -275140,7 +258936,7 @@ name: results in transport along namespace: external def: "Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l " [] xref: RO:0002341 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: RO:0002337 ! related via localization to [Typedef] @@ -275149,7 +258945,7 @@ name: results in transport to from or in namespace: external xref: RO:0002344 property_value: IAO:0000112 "'mitochondrial transport' results_in_transport_to_from_or_in some mitochondrion (GO:0005739)" xsd:string -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: RO:0002337 ! related via localization to [Typedef] @@ -275173,10 +258969,9 @@ comment: t1 simultaneous_with t2 iff:= t1 before_or_simultaneous_with t2 and n subset: ro-eco xref: RO:0002082 property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 is_transitive: true -is_a: ends ! ends is_a: RO:0002081 ! before or simultaneous with -is_a: starts ! starts [Typedef] id: site_of @@ -275192,7 +258987,7 @@ namespace: uberon def: "inverse of has skeleton" [] subset: RO:0002259 xref: RO:0002576 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 domain: CARO:0000003 ! connected anatomical structure range: CARO:0000003 ! connected anatomical structure is_a: part_of ! part_of @@ -275206,6 +259001,7 @@ subset: ro-eco xref: RO:0002223 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "Allen" xsd:string is_a: part_of ! part_of is_a: RO:0002222 ! temporally related to @@ -275222,6 +259018,7 @@ xref: RO:0002224 property_value: IAO:0000112 "Every insulin receptor signaling pathway starts with the binding of a ligand to the insulin receptor" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "started by" xsd:string is_transitive: true is_a: has_part ! has part @@ -275257,7 +259054,7 @@ namespace: uberon def: "x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x" [] xref: RO:0002219 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: RO:0001900 RO:0001901 is_a: adjacent_to ! adjacent to inverse_of: surrounds ! surrounds @@ -275270,7 +259067,7 @@ def: "inverse of surrounded by" [] subset: RO:0002259 xref: RO:0002221 property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: RO:0001900 RO:0001901 is_a: adjacent_to ! adjacent to @@ -275286,7 +259083,7 @@ name: transformation of namespace: uberon def: "x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships" [] xref: RO:0002494 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_transitive: true is_a: develops_from ! develops from @@ -275321,7 +259118,7 @@ xref: RO:0002376 property_value: IAO:0000112 "Deschutes River tributary_of Columbia River" xsd:string property_value: IAO:0000112 "inferior epigastric vein tributary_of external iliac vein" xsd:string property_value: IAO:0000114 IAO:0000428 -property_value: IAO:0000117 "Chris Mungall" xsd:string +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "drains into" xsd:string property_value: IAO:0000118 "drains to" xsd:string property_value: IAO:0000118 "tributary channel of" xsd:string diff --git a/patterns/definitions.owl b/patterns/definitions.owl index ba6a261ae..294add3fa 100644 --- a/patterns/definitions.owl +++ b/patterns/definitions.owl @@ -1,4 +1,4 @@ -Prefix(:=) +Prefix(:=) Prefix(owl:=) Prefix(rdf:=) Prefix(xml:=) @@ -7,8 +7,9 @@ Prefix(rdfs:=) Ontology( - -Annotation(owl:versionInfo "2023-02-10"^^xsd:string) + +Annotation(owl:versionInfo "2023-03-16") + ) \ No newline at end of file diff --git a/src/ontology/diffs/cl-diff.md b/src/ontology/diffs/cl-diff.md index 4ad7ed51f..c880394f8 100644 --- a/src/ontology/diffs/cl-diff.md +++ b/src/ontology/diffs/cl-diff.md @@ -2,12 +2,12 @@ ## Left - Ontology IRI: `http://purl.obolibrary.org/obo/cl.owl` -- Version IRI: `http://purl.obolibrary.org/obo/cl/releases/2023-01-09/cl.owl` +- Version IRI: `http://purl.obolibrary.org/obo/cl/releases/2023-02-19/cl.owl` - Loaded from: `http://purl.obolibrary.org/obo/cl.owl` ## Right - Ontology IRI: `http://purl.obolibrary.org/obo/cl.owl` -- Version IRI: `http://purl.obolibrary.org/obo/cl/releases/2023-02-15/cl.owl` +- Version IRI: `http://purl.obolibrary.org/obo/cl/releases/2023-03-21/cl.owl` - Loaded from: `file:/work/src/ontology/../../cl.owl` ### Ontology imports @@ -16,4026 +16,52822 @@ ### Ontology annotations #### Removed -- [versionInfo](http://www.w3.org/2002/07/owl#versionInfo) "2023-01-09"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [versionInfo](http://www.w3.org/2002/07/owl#versionInfo) "2023-02-19" #### Added -- [versionInfo](http://www.w3.org/2002/07/owl#versionInfo) "2023-02-15"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [versionInfo](http://www.w3.org/2002/07/owl#versionInfo) "2023-03-21" -### Axl+ dendritic cell, human `http://purl.obolibrary.org/obo/CL_0017009` +### (R)-noradrenaline `http://purl.obolibrary.org/obo/CHEBI_18357` +#### Removed +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB00368" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "norepinephrine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:LNR" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The R-enantiomer of noradrenaline." + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D00076" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:18357" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:2804840" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [label](http://www.w3.org/2000/01/rdf-schema#label) "(R)-noradrenaline" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "norepinefrina" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:4231961" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:1960" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Norepinephrine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(-)-arterenol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:1" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:51-41-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "SFLSHLFXELFNJZ-QMMMGPOBSA-N" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "L-NOREPINEPHRINE" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C8H11NO3" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:258884" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00547" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "169.07389" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "norepinephrinum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:25592" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:2804840" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00001424" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Norepinephrine" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(R)-norepinephrine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000216" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(-)-norepinephrine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(R)-(-)-norepinephrine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:51-41-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14668" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Arterenol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "L-Noradrenaline" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "norepinephrine" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WHO_MedNet" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:43725" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [mass](http://purl.obolibrary.org/obo/chebi/mass) "169.17780" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "NC[C@H](O)c1ccc(O)c(O)c1" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(-)-noradrenaline" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPHAR" + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Noradrenaline" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- Class: [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [alpha-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35569) + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [neurotransmitter](http://purl.obolibrary.org/obo/CHEBI_25512) + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) SubClassOf [is_enantiomer_of](http://purl.obolibrary.org/obo/chebi#is_enantiomer_of) some [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [vasoconstrictor agent](http://purl.obolibrary.org/obo/CHEBI_50514) + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) SubClassOf [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [sympathomimetic agent](http://purl.obolibrary.org/obo/CHEBI_35524) + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) + +- [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + + + +### (R)-noradrenaline(1+) `http://purl.obolibrary.org/obo/CHEBI_72587` +#### Removed +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C8H12NO3" + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+1" + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "SFLSHLFXELFNJZ-QMMMGPOBSA-O" + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [mass](http://purl.obolibrary.org/obo/chebi/mass) "170.187" + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An organic cation that is the conjugate acid of (R)-noradrenaline, obtained by protonation of the priamry amino group; major species at pH 7.3." + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:72587" + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(R)-noradrenalinium cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "(2R)-2-(3,4-dihydroxyphenyl)-2-hydroxyethanaminium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(R)-noradrenaline" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:E5E" + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "170.08117" + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1/t8-/m0/s1" + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C=1(C=CC(=CC1O)[C@H](C[NH3+])O)O" + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(R)-noradrenalinium(1+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [label](http://www.w3.org/2000/01/rdf-schema#label) "(R)-noradrenaline(1+)" + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(R)-noradrenaline cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) SubClassOf [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) + + + +### (S)-noradrenaline `http://purl.obolibrary.org/obo/CHEBI_33571` +#### Removed +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "SFLSHLFXELFNJZ-MRVPVSSYSA-N" + +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C8H11NO3" + +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:2937999" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) [label](http://www.w3.org/2000/01/rdf-schema#label) "(S)-noradrenaline" + +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) [mass](http://purl.obolibrary.org/obo/chebi/mass) "169.17788" + +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:2937999" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33571" + +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The S-enantiomer of noradrenaline." + +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "NC[C@@H](O)c1ccc(O)c(O)c1" + +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m1/s1" + +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LINCS:LSM-37072" + +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "169.07389" + +- Class: [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) + +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) SubClassOf [is_enantiomer_of](http://purl.obolibrary.org/obo/chebi#is_enantiomer_of) some [(R)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_18357) + +- [(S)-noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33571) SubClassOf [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) + + + +### 11-hydroxy steroid `http://purl.obolibrary.org/obo/CHEBI_36841` +#### Removed +- [11-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36841) [label](http://www.w3.org/2000/01/rdf-schema#label) "11-hydroxy steroid" + +- [11-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36841) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [11-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36841) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [11-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36841) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36841" + +- [11-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36841) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "11-hydroxy steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [11-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36841) + +- [11-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36841) SubClassOf [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) + + + +### 11beta-hydroxy steroid `http://purl.obolibrary.org/obo/CHEBI_35346` +#### Removed +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [label](http://www.w3.org/2000/01/rdf-schema#label) "11beta-hydroxy steroid" + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:19134" + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any 11-hydroxy steroid in which the hydroxy group at position 11 has beta- configuration." + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13774" + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "11beta-Hydroxysteroid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [mass](http://purl.obolibrary.org/obo/chebi/mass) "275.450" + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35346" + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "11beta-hydroxysteroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "275.23749" + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C12(CCCCC1CCC3C2[C@H](CC4(C3CCC4*)C)O)C" + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:738" + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "11beta-hydroxy steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C19H31OR" + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01058" + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "an 11beta-hydroxysteroid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- Class: [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) + +- [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) SubClassOf [11-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36841) + + + +### 17-hydroxy steroid `http://purl.obolibrary.org/obo/CHEBI_36838` +#### Removed +- [17-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36838) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [17-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36838) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "17-hydroxy steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [17-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36838) [label](http://www.w3.org/2000/01/rdf-schema#label) "17-hydroxy steroid" + +- [17-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36838) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [17-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36838) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36838" + +- [17-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36838) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A hydroxy steroid carrying a hydroxy group at position 17." + +- Class: [17-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36838) + +- [17-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36838) SubClassOf [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) + + + +### 17beta-hydroxy steroid `http://purl.obolibrary.org/obo/CHEBI_35343` +#### Removed +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [mass](http://purl.obolibrary.org/obo/chebi/mass) "261.423" + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "17beta-hydroxysteroid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35343" + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "17beta-hydroxy steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a 17beta-hydroxy steroid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "CC12CCC3C(CCC4CCCCC34[*])C1CC[C@@H]2O" + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C03051" + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:794" + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "261.22184" + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:17-beta-Hydroxysteroids" + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:19176" + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [label](http://www.w3.org/2000/01/rdf-schema#label) "17beta-hydroxy steroid" + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "17beta-hydroxysteroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C18H29OR" + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A 17-hydroxy steroid in which the hydroxy group at position 17 has a beta-configuration." + +- Class: [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) + +- [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) SubClassOf [17-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36838) + + + +### 18-oxo steroid `http://purl.obolibrary.org/obo/CHEBI_36887` +#### Removed +- [18-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36887) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [18-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36887) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36887" + +- [18-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36887) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "18-oxo steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [18-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36887) [label](http://www.w3.org/2000/01/rdf-schema#label) "18-oxo steroid" + +- [18-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36887) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [18-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36887) + +- [18-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36887) SubClassOf [oxo steroid](http://purl.obolibrary.org/obo/CHEBI_35789) + + + +### 2-carboxyethyl group `http://purl.obolibrary.org/obo/CHEBI_50329` +#### Removed +- [2-carboxyethyl group](http://purl.obolibrary.org/obo/CHEBI_50329) [label](http://www.w3.org/2000/01/rdf-schema#label) "2-carboxyethyl group" + +- [2-carboxyethyl group](http://purl.obolibrary.org/obo/CHEBI_50329) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "73.02895" + +- [2-carboxyethyl group](http://purl.obolibrary.org/obo/CHEBI_50329) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C3H5O2" + +- [2-carboxyethyl group](http://purl.obolibrary.org/obo/CHEBI_50329) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "2-carboxyethyl" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [2-carboxyethyl group](http://purl.obolibrary.org/obo/CHEBI_50329) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glutamic acid side-chain" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [2-carboxyethyl group](http://purl.obolibrary.org/obo/CHEBI_50329) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C(CC(=O)O)*" + +- [2-carboxyethyl group](http://purl.obolibrary.org/obo/CHEBI_50329) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [2-carboxyethyl group](http://purl.obolibrary.org/obo/CHEBI_50329) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50329" + +- [2-carboxyethyl group](http://purl.obolibrary.org/obo/CHEBI_50329) [mass](http://purl.obolibrary.org/obo/chebi/mass) "73.07060" + +- [2-carboxyethyl group](http://purl.obolibrary.org/obo/CHEBI_50329) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [2-carboxyethyl group](http://purl.obolibrary.org/obo/CHEBI_50329) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [2-carboxyethyl group](http://purl.obolibrary.org/obo/CHEBI_50329) + +- [2-carboxyethyl group](http://purl.obolibrary.org/obo/CHEBI_50329) SubClassOf [proteinogenic amino-acid side-chain group](http://purl.obolibrary.org/obo/CHEBI_50325) + + + +### 20-oxo steroid `http://purl.obolibrary.org/obo/CHEBI_36885` +#### Removed +- [20-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36885) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "20-oxo steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [20-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36885) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [20-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36885) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36885" + +- [20-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36885) [label](http://www.w3.org/2000/01/rdf-schema#label) "20-oxo steroid" + +- [20-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36885) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An oxo steroid carrying an oxo group at position 20." + +- [20-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36885) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [20-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36885) + +- [20-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36885) SubClassOf [oxo steroid](http://purl.obolibrary.org/obo/CHEBI_35789) + + + +### 21-hydroxy steroid `http://purl.obolibrary.org/obo/CHEBI_35344` +#### Removed +- [21-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35344) [label](http://www.w3.org/2000/01/rdf-schema#label) "21-hydroxy steroid" + +- [21-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35344) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35344" + +- [21-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35344) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "21-hydroxy steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [21-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35344) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:19803" + +- [21-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35344) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [21-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35344) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "21-Hydroxysteroid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [21-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35344) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:1300" + +- [21-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35344) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "21-hydroxysteroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [21-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35344) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [21-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35344) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C02506" + +- [21-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35344) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13596" + +- Class: [21-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35344) + +- [21-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35344) SubClassOf [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) + + + +### 24G7 epitope `http://purl.obolibrary.org/obo/CHEBI_142163` +#### Removed +- [24G7 epitope](http://purl.obolibrary.org/obo/CHEBI_142163) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "134.04801" + +- [24G7 epitope](http://purl.obolibrary.org/obo/CHEBI_142163) [mass](http://purl.obolibrary.org/obo/chebi/mass) "134.136" + +- [24G7 epitope](http://purl.obolibrary.org/obo/CHEBI_142163) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [24G7 epitope](http://purl.obolibrary.org/obo/CHEBI_142163) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C7H6N2O" + +- [24G7 epitope](http://purl.obolibrary.org/obo/CHEBI_142163) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [24G7 epitope](http://purl.obolibrary.org/obo/CHEBI_142163) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An antigenic epitope recognized by an anti-bilirubin monoclonal antibody designated 24G7. A substructure of bilirubin IXalpha, it is the region containing the oxo group at C-1, the methyl group at C-2, C-(4, 5, 6, 9), and N-21 and -22." + +- [24G7 epitope](http://purl.obolibrary.org/obo/CHEBI_142163) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:142163" + +- [24G7 epitope](http://purl.obolibrary.org/obo/CHEBI_142163) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C(=CC(NC(=*)*)=*)(NC(C(C)=*)=O)*" + +- [24G7 epitope](http://purl.obolibrary.org/obo/CHEBI_142163) [label](http://www.w3.org/2000/01/rdf-schema#label) "24G7 epitope" + +- [24G7 epitope](http://purl.obolibrary.org/obo/CHEBI_142163) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [24G7 epitope](http://purl.obolibrary.org/obo/CHEBI_142163) + +- [24G7 epitope](http://purl.obolibrary.org/obo/CHEBI_142163) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [epitope](http://purl.obolibrary.org/obo/CHEBI_53000) + +- [24G7 epitope](http://purl.obolibrary.org/obo/CHEBI_142163) SubClassOf [group](http://purl.obolibrary.org/obo/CHEBI_24433) + + + +### 3-hydroxy steroid `http://purl.obolibrary.org/obo/CHEBI_36834` +#### Removed +- [3-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36834) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [3-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36834) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [3-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36834) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3-hydroxy steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [3-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36834) [label](http://www.w3.org/2000/01/rdf-schema#label) "3-hydroxy steroid" + +- [3-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36834) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36834" + +- [3-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36834) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any hydroxy steroid carrying a hydroxy group at position 3." + +- Class: [3-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36834) + +- [3-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36834) SubClassOf [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) + + + +### 3-oxo steroid `http://purl.obolibrary.org/obo/CHEBI_47788` +#### Removed +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [label](http://www.w3.org/2000/01/rdf-schema#label) "3-oxo steroid" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "273.22184" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3-oxo steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:20182" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any oxo steroid where an oxo substituent is located at position 3." + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:71186" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:1653" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [mass](http://purl.obolibrary.org/obo/chebi/mass) "273.434" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3-Oxosteroid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3-oxosteroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:3-Oxosteroids" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9811880" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "SUBMITTER" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C19H29OR" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:47788" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13607" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C12C(C3C(C(CC3)*)(C)CC1)CCC4C2(CCC(C4)=O)C" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a 3-oxosteroid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01876" + +- Class: [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) SubClassOf [oxo steroid](http://purl.obolibrary.org/obo/CHEBI_35789) + +- [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) SubClassOf [cyclic ketone](http://purl.obolibrary.org/obo/CHEBI_3992) + + + +### 3-oxo-Delta(4) steroid `http://purl.obolibrary.org/obo/CHEBI_47909` +#### Removed +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a 3-oxo-Delta(4)-steroid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:3-Oxo-Delta-4-Steroids" + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:1626" + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3-oxo Delta(4)-steroid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:47909" + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3-oxo-Delta(4) steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [label](http://www.w3.org/2000/01/rdf-schema#label) "3-oxo-Delta(4) steroid" + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3-oxo Delta(4)-steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13604" + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3-Oxo-delta4-steroid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "271.20619" + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A 3-oxo steroid conjugated to a C=C double bond at the alpha,beta position." + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00619" + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:20157" + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [mass](http://purl.obolibrary.org/obo/chebi/mass) "271.418" + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C19H27OR" + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C12C(C3C(C(CC3)*)(C)CC1)CCC=4C2(CCC(C4)=O)C" + +- Class: [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [3-oxo-Delta(4)-steroid group](http://purl.obolibrary.org/obo/CHEBI_136849) + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) SubClassOf [3-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_47788) + +- [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) SubClassOf [enone](http://purl.obolibrary.org/obo/CHEBI_51689) + + + +### 3-oxo-Delta(4)-steroid group `http://purl.obolibrary.org/obo/CHEBI_136849` +#### Removed +- [3-oxo-Delta(4)-steroid group](http://purl.obolibrary.org/obo/CHEBI_136849) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [3-oxo-Delta(4)-steroid group](http://purl.obolibrary.org/obo/CHEBI_136849) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C6H6O" + +- [3-oxo-Delta(4)-steroid group](http://purl.obolibrary.org/obo/CHEBI_136849) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An organic group derived from any 3-oxo-Delta(4)-steroid." + +- [3-oxo-Delta(4)-steroid group](http://purl.obolibrary.org/obo/CHEBI_136849) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [3-oxo-Delta(4)-steroid group](http://purl.obolibrary.org/obo/CHEBI_136849) [label](http://www.w3.org/2000/01/rdf-schema#label) "3-oxo-Delta(4)-steroid group" + +- [3-oxo-Delta(4)-steroid group](http://purl.obolibrary.org/obo/CHEBI_136849) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [3-oxo-Delta(4)-steroid group](http://purl.obolibrary.org/obo/CHEBI_136849) [mass](http://purl.obolibrary.org/obo/chebi/mass) "94.111" + +- [3-oxo-Delta(4)-steroid group](http://purl.obolibrary.org/obo/CHEBI_136849) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "94.04186" + +- [3-oxo-Delta(4)-steroid group](http://purl.obolibrary.org/obo/CHEBI_136849) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C1=C(C*)*C(CC1=O)*" + +- [3-oxo-Delta(4)-steroid group](http://purl.obolibrary.org/obo/CHEBI_136849) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a 3-oxo-Delta4-steroid group" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [3-oxo-Delta(4)-steroid group](http://purl.obolibrary.org/obo/CHEBI_136849) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:136849" + +- Class: [3-oxo-Delta(4)-steroid group](http://purl.obolibrary.org/obo/CHEBI_136849) + +- [3-oxo-Delta(4)-steroid group](http://purl.obolibrary.org/obo/CHEBI_136849) SubClassOf [organic group](http://purl.obolibrary.org/obo/CHEBI_33247) + + + +### 5beta steroid `http://purl.obolibrary.org/obo/CHEBI_136889` +#### Removed +- [5beta steroid](http://purl.obolibrary.org/obo/CHEBI_136889) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "5beta-steroid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [5beta steroid](http://purl.obolibrary.org/obo/CHEBI_136889) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:136889" + +- [5beta steroid](http://purl.obolibrary.org/obo/CHEBI_136889) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "5beta-steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [5beta steroid](http://purl.obolibrary.org/obo/CHEBI_136889) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [5beta steroid](http://purl.obolibrary.org/obo/CHEBI_136889) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [5beta steroid](http://purl.obolibrary.org/obo/CHEBI_136889) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "5beta steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [5beta steroid](http://purl.obolibrary.org/obo/CHEBI_136889) [label](http://www.w3.org/2000/01/rdf-schema#label) "5beta steroid" + +- [5beta steroid](http://purl.obolibrary.org/obo/CHEBI_136889) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any steroid that has beta-configuration at position 5." + +- Class: [5beta steroid](http://purl.obolibrary.org/obo/CHEBI_136889) + +- [5beta steroid](http://purl.obolibrary.org/obo/CHEBI_136889) SubClassOf [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) + + + +### 5beta-cholane `http://purl.obolibrary.org/obo/CHEBI_20664` +#### Removed +- [5beta-cholane](http://purl.obolibrary.org/obo/CHEBI_20664) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "QSHQKIURKJITMZ-OBUPQJQESA-N" + +- [5beta-cholane](http://purl.obolibrary.org/obo/CHEBI_20664) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "330.32865" + +- [5beta-cholane](http://purl.obolibrary.org/obo/CHEBI_20664) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:20664" + +- [5beta-cholane](http://purl.obolibrary.org/obo/CHEBI_20664) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:2048472" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [5beta-cholane](http://purl.obolibrary.org/obo/CHEBI_20664) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C24H42/c1-5-8-17(2)20-12-13-21-19-11-10-18-9-6-7-15-23(18,3)22(19)14-16-24(20,21)4/h17-22H,5-16H2,1-4H3/t17-,18+,19+,20-,21+,22+,23+,24-/m1/s1" + +- [5beta-cholane](http://purl.obolibrary.org/obo/CHEBI_20664) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C24H42" + +- [5beta-cholane](http://purl.obolibrary.org/obo/CHEBI_20664) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "5beta-cholane" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [5beta-cholane](http://purl.obolibrary.org/obo/CHEBI_20664) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [5beta-cholane](http://purl.obolibrary.org/obo/CHEBI_20664) [mass](http://purl.obolibrary.org/obo/chebi/mass) "330.59028" + +- [5beta-cholane](http://purl.obolibrary.org/obo/CHEBI_20664) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [5beta-cholane](http://purl.obolibrary.org/obo/CHEBI_20664) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [5beta-cholane](http://purl.obolibrary.org/obo/CHEBI_20664) [label](http://www.w3.org/2000/01/rdf-schema#label) "5beta-cholane" + +- [5beta-cholane](http://purl.obolibrary.org/obo/CHEBI_20664) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H][C@@]12CCCC[C@]1(C)[C@@]1([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC2)[C@H](C)CCC" + +- Class: [5beta-cholane](http://purl.obolibrary.org/obo/CHEBI_20664) + +- [5beta-cholane](http://purl.obolibrary.org/obo/CHEBI_20664) SubClassOf [cholane](http://purl.obolibrary.org/obo/CHEBI_35519) + + + +### 5beta-cholanic acid `http://purl.obolibrary.org/obo/CHEBI_36238` +#### Removed +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H][C@@]12CCCC[C@]1(C)[C@@]1([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC2)[C@H](C)CCC(O)=O" + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "5beta-cholan-24-oic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "360.30283" + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(5beta)-cholan-24-oic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ursocholanic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36238" + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17+,18+,19-,20+,21+,23+,24-/m1/s1" + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "5beta-cholanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:546-18-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LIPID_MAPS_instance:LMST04010441" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "LIPID MAPS" + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [label](http://www.w3.org/2000/01/rdf-schema#label) "5beta-cholanic acid" + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "5beta-cholanic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(5beta,17beta)-gamma-methylandrostane-17-butanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [mass](http://purl.obolibrary.org/obo/chebi/mass) "360.57320" + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "RPKLZQLYODPWTM-LVVAJZGHSA-N" + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:3214794" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C24H40O2" + +- Class: [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) SubClassOf [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) + +- [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) SubClassOf [5beta-cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36248) + + + +### 5beta-cholanic acids `http://purl.obolibrary.org/obo/CHEBI_36248` +#### Removed +- [5beta-cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36248) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Members of the class of cholanic acids based on a 5beta-cholane skeleton." + +- [5beta-cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36248) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [5beta-cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36248) [label](http://www.w3.org/2000/01/rdf-schema#label) "5beta-cholanic acids" + +- [5beta-cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36248) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36248" + +- [5beta-cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36248) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [5beta-cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36248) + +- [5beta-cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36248) SubClassOf [5beta steroid](http://purl.obolibrary.org/obo/CHEBI_136889) + +- [5beta-cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36248) SubClassOf [cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36278) + +- [5beta-cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36248) SubClassOf [has_parent_hydride](http://purl.obolibrary.org/obo/chebi#has_parent_hydride) some [5beta-cholane](http://purl.obolibrary.org/obo/CHEBI_20664) + + + +### B-1b B cell `http://purl.obolibrary.org/obo/CL_0000821` +#### Removed +- [B-1b B cell](http://purl.obolibrary.org/obo/CL_0000821) EquivalentTo [B-1 B cell](http://purl.obolibrary.org/obo/CL_0000819) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) + +- [B-1b B cell](http://purl.obolibrary.org/obo/CL_0000821) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +#### Added +- [B-1b B cell](http://purl.obolibrary.org/obo/CL_0000821) EquivalentTo [B-1 B cell](http://purl.obolibrary.org/obo/CL_0000819) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) + +- [B-1b B cell](http://purl.obolibrary.org/obo/CL_0000821) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + + +### B-2 B cell `http://purl.obolibrary.org/obo/CL_0000822` +#### Removed +- [B-2 B cell](http://purl.obolibrary.org/obo/CL_0000822) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) + +- [B-2 B cell](http://purl.obolibrary.org/obo/CL_0000822) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879) + +#### Added +- [B-2 B cell](http://purl.obolibrary.org/obo/CL_0000822) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) + +- [B-2 B cell](http://purl.obolibrary.org/obo/CL_0000822) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879) + + +### BRAND_NAME `http://purl.obolibrary.org/obo/chebi#BRAND_NAME` +#### Removed +- AnnotationProperty: [BRAND_NAME](http://purl.obolibrary.org/obo/chebi#BRAND_NAME) + +- [BRAND_NAME](http://purl.obolibrary.org/obo/chebi#BRAND_NAME) SubPropertyOf: [synonym_type_property](http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty) + + + +### Bm1 B cell `http://purl.obolibrary.org/obo/CL_0000961` +#### Removed +- [Bm1 B cell](http://purl.obolibrary.org/obo/CL_0000961) EquivalentTo [follicular B cell](http://purl.obolibrary.org/obo/CL_0000843) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880)) + +- [Bm1 B cell](http://purl.obolibrary.org/obo/CL_0000961) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + +#### Added +- [Bm1 B cell](http://purl.obolibrary.org/obo/CL_0000961) EquivalentTo [follicular B cell](http://purl.obolibrary.org/obo/CL_0000843) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) + +- [Bm1 B cell](http://purl.obolibrary.org/obo/CL_0000961) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + + +### Bm2' B cell `http://purl.obolibrary.org/obo/CL_0000964` +#### Removed +- [Bm2' B cell](http://purl.obolibrary.org/obo/CL_0000964) EquivalentTo [germinal center B cell](http://purl.obolibrary.org/obo/CL_0000844) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [regulation of germinal center formation](http://purl.obolibrary.org/obo/GO_0002634)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880)) + +- [Bm2' B cell](http://purl.obolibrary.org/obo/CL_0000964) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880) + +#### Added +- [Bm2' B cell](http://purl.obolibrary.org/obo/CL_0000964) EquivalentTo [germinal center B cell](http://purl.obolibrary.org/obo/CL_0000844) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [regulation of germinal center formation](http://purl.obolibrary.org/obo/GO_0002634)) + +- [Bm2' B cell](http://purl.obolibrary.org/obo/CL_0000964) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880) + + +### Bm3 B cell `http://purl.obolibrary.org/obo/CL_0000965` +#### Removed +- [Bm3 B cell](http://purl.obolibrary.org/obo/CL_0000965) EquivalentTo [germinal center B cell](http://purl.obolibrary.org/obo/CL_0000844) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lactosylceramide 4-alpha-galactosyltransferase](http://purl.obolibrary.org/obo/PR_000003516)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [somatic hypermutation of immunoglobulin genes](http://purl.obolibrary.org/obo/GO_0016446)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) + +- [Bm3 B cell](http://purl.obolibrary.org/obo/CL_0000965) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738) + +#### Added +- [Bm3 B cell](http://purl.obolibrary.org/obo/CL_0000965) EquivalentTo [germinal center B cell](http://purl.obolibrary.org/obo/CL_0000844) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lactosylceramide 4-alpha-galactosyltransferase](http://purl.obolibrary.org/obo/PR_000003516)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [somatic hypermutation of immunoglobulin genes](http://purl.obolibrary.org/obo/GO_0016446)) + +- [Bm3 B cell](http://purl.obolibrary.org/obo/CL_0000965) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738) + + +### Bm3-delta B cell `http://purl.obolibrary.org/obo/CL_0000963` +#### Removed +- [Bm3-delta B cell](http://purl.obolibrary.org/obo/CL_0000963) EquivalentTo [germinal center B cell](http://purl.obolibrary.org/obo/CL_0000844) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) + +- [Bm3-delta B cell](http://purl.obolibrary.org/obo/CL_0000963) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753) + +#### Added +- [Bm3-delta B cell](http://purl.obolibrary.org/obo/CL_0000963) EquivalentTo [germinal center B cell](http://purl.obolibrary.org/obo/CL_0000844) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) + +- [Bm3-delta B cell](http://purl.obolibrary.org/obo/CL_0000963) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753) + + +### Bm4 B cell `http://purl.obolibrary.org/obo/CL_0000966` +#### Removed +- [Bm4 B cell](http://purl.obolibrary.org/obo/CL_0000966) EquivalentTo [germinal center B cell](http://purl.obolibrary.org/obo/CL_0000844) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [somatic hypermutation of immunoglobulin genes](http://purl.obolibrary.org/obo/GO_0016446)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lactosylceramide 4-alpha-galactosyltransferase](http://purl.obolibrary.org/obo/PR_000003516)) + +- [Bm4 B cell](http://purl.obolibrary.org/obo/CL_0000966) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lactosylceramide 4-alpha-galactosyltransferase](http://purl.obolibrary.org/obo/PR_000003516) + +- [Bm4 B cell](http://purl.obolibrary.org/obo/CL_0000966) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738) + +#### Added +- [Bm4 B cell](http://purl.obolibrary.org/obo/CL_0000966) EquivalentTo [germinal center B cell](http://purl.obolibrary.org/obo/CL_0000844) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lactosylceramide 4-alpha-galactosyltransferase](http://purl.obolibrary.org/obo/PR_000003516)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [somatic hypermutation of immunoglobulin genes](http://purl.obolibrary.org/obo/GO_0016446)) + +- [Bm4 B cell](http://purl.obolibrary.org/obo/CL_0000966) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lactosylceramide 4-alpha-galactosyltransferase](http://purl.obolibrary.org/obo/PR_000003516) + +- [Bm4 B cell](http://purl.obolibrary.org/obo/CL_0000966) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738) + + +### Bm5 B cell `http://purl.obolibrary.org/obo/CL_0000967` +#### Removed +- [Bm5 B cell](http://purl.obolibrary.org/obo/CL_0000967) EquivalentTo [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [germinal center B cell differentiation](http://purl.obolibrary.org/obo/GO_0002314)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [somatic hypermutation of immunoglobulin genes](http://purl.obolibrary.org/obo/GO_0016446)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) + +#### Added +- [Bm5 B cell](http://purl.obolibrary.org/obo/CL_0000967) EquivalentTo [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [germinal center B cell differentiation](http://purl.obolibrary.org/obo/GO_0002314)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [somatic hypermutation of immunoglobulin genes](http://purl.obolibrary.org/obo/GO_0016446)) + + +### Bronsted acid `http://purl.obolibrary.org/obo/CHEBI_39141` +#### Removed +- [Bronsted acid](http://purl.obolibrary.org/obo/CHEBI_39141) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acide de Bronsted" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [Bronsted acid](http://purl.obolibrary.org/obo/CHEBI_39141) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:39141" + +- [Bronsted acid](http://purl.obolibrary.org/obo/CHEBI_39141) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydron donor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [Bronsted acid](http://purl.obolibrary.org/obo/CHEBI_39141) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [Bronsted acid](http://purl.obolibrary.org/obo/CHEBI_39141) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Bronsted acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [Bronsted acid](http://purl.obolibrary.org/obo/CHEBI_39141) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "donneur d'hydron" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [Bronsted acid](http://purl.obolibrary.org/obo/CHEBI_39141) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Bronsted-Saeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Bronsted acid](http://purl.obolibrary.org/obo/CHEBI_39141) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [Bronsted acid](http://purl.obolibrary.org/obo/CHEBI_39141) [label](http://www.w3.org/2000/01/rdf-schema#label) "Bronsted acid" + +- [Bronsted acid](http://purl.obolibrary.org/obo/CHEBI_39141) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecular entity capable of donating a hydron to an acceptor (Bronsted base)." + +- Class: [Bronsted acid](http://purl.obolibrary.org/obo/CHEBI_39141) + +- [Bronsted acid](http://purl.obolibrary.org/obo/CHEBI_39141) SubClassOf [acid](http://purl.obolibrary.org/obo/CHEBI_37527) + +- [Bronsted acid](http://purl.obolibrary.org/obo/CHEBI_39141) SubClassOf [donor](http://purl.obolibrary.org/obo/CHEBI_17891) + + + +### Bronsted base `http://purl.obolibrary.org/obo/CHEBI_39142` +#### Removed +- [Bronsted base](http://purl.obolibrary.org/obo/CHEBI_39142) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Bronsted-Base" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Bronsted base](http://purl.obolibrary.org/obo/CHEBI_39142) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [Bronsted base](http://purl.obolibrary.org/obo/CHEBI_39142) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydron acceptor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [Bronsted base](http://purl.obolibrary.org/obo/CHEBI_39142) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Bronsted base" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [Bronsted base](http://purl.obolibrary.org/obo/CHEBI_39142) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "base de Bronsted" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [Bronsted base](http://purl.obolibrary.org/obo/CHEBI_39142) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [Bronsted base](http://purl.obolibrary.org/obo/CHEBI_39142) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:39142" + +- [Bronsted base](http://purl.obolibrary.org/obo/CHEBI_39142) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecular entity capable of accepting a hydron from a donor (Bronsted acid)." + +- [Bronsted base](http://purl.obolibrary.org/obo/CHEBI_39142) [label](http://www.w3.org/2000/01/rdf-schema#label) "Bronsted base" + +- [Bronsted base](http://purl.obolibrary.org/obo/CHEBI_39142) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "accepteur d'hydron" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- Class: [Bronsted base](http://purl.obolibrary.org/obo/CHEBI_39142) + +- [Bronsted base](http://purl.obolibrary.org/obo/CHEBI_39142) SubClassOf [base](http://purl.obolibrary.org/obo/CHEBI_22695) + +- [Bronsted base](http://purl.obolibrary.org/obo/CHEBI_39142) SubClassOf [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) + + + +### C19-steroid `http://purl.obolibrary.org/obo/CHEBI_131621` +#### Removed +- [C19-steroid](http://purl.obolibrary.org/obo/CHEBI_131621) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [C19-steroid](http://purl.obolibrary.org/obo/CHEBI_131621) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:131621" + +- [C19-steroid](http://purl.obolibrary.org/obo/CHEBI_131621) [label](http://www.w3.org/2000/01/rdf-schema#label) "C19-steroid" + +- [C19-steroid](http://purl.obolibrary.org/obo/CHEBI_131621) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [C19-steroid](http://purl.obolibrary.org/obo/CHEBI_131621) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "C19-steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [C19-steroid](http://purl.obolibrary.org/obo/CHEBI_131621) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A steroid compound with a structure based on a 19-carbon (androstane) skeleton." + +- Class: [C19-steroid](http://purl.obolibrary.org/obo/CHEBI_131621) + +- [C19-steroid](http://purl.obolibrary.org/obo/CHEBI_131621) SubClassOf [has_parent_hydride](http://purl.obolibrary.org/obo/chebi#has_parent_hydride) some [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) + +- [C19-steroid](http://purl.obolibrary.org/obo/CHEBI_131621) SubClassOf [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) + + + +### C21-steroid `http://purl.obolibrary.org/obo/CHEBI_61313` +#### Removed +- [C21-steroid](http://purl.obolibrary.org/obo/CHEBI_61313) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "288.28170" + +- [C21-steroid](http://purl.obolibrary.org/obo/CHEBI_61313) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [C21-steroid](http://purl.obolibrary.org/obo/CHEBI_61313) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [C21-steroid](http://purl.obolibrary.org/obo/CHEBI_61313) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [C21-steroid](http://purl.obolibrary.org/obo/CHEBI_61313) [mass](http://purl.obolibrary.org/obo/chebi/mass) "288.511" + +- [C21-steroid](http://purl.obolibrary.org/obo/CHEBI_61313) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C21H36/c1-4-15-9-11-18-17-10-8-16-7-5-6-13-20(16,2)19(17)12-14-21(15,18)3/h15-19H,4-14H2,1-3H3" + +- [C21-steroid](http://purl.obolibrary.org/obo/CHEBI_61313) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C21H36" + +- [C21-steroid](http://purl.obolibrary.org/obo/CHEBI_61313) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C1CCCC2C1(C3C(CC2)C4C(CC3)(C(CC4)CC)C)C" + +- [C21-steroid](http://purl.obolibrary.org/obo/CHEBI_61313) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:61313" + +- [C21-steroid](http://purl.obolibrary.org/obo/CHEBI_61313) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a C21-steroid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [C21-steroid](http://purl.obolibrary.org/obo/CHEBI_61313) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A steroid that has a structure based on a 21-carbon (pregnane) skeleton. Note that individual examples may have ring substituents at other positions and/or contain double bonds, aromatic A-rings, expanded/contracted rings etc., so the formula and mass may vary from that given for the generic structure." + +- [C21-steroid](http://purl.obolibrary.org/obo/CHEBI_61313) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "JWMFYGXQPXQEEM-UHFFFAOYSA-N" + +- [C21-steroid](http://purl.obolibrary.org/obo/CHEBI_61313) [label](http://www.w3.org/2000/01/rdf-schema#label) "C21-steroid" + +- Class: [C21-steroid](http://purl.obolibrary.org/obo/CHEBI_61313) + +- [C21-steroid](http://purl.obolibrary.org/obo/CHEBI_61313) SubClassOf [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) + + + +### C21-steroid hormone `http://purl.obolibrary.org/obo/CHEBI_64600` +#### Removed +- [C21-steroid hormone](http://purl.obolibrary.org/obo/CHEBI_64600) [label](http://www.w3.org/2000/01/rdf-schema#label) "C21-steroid hormone" + +- [C21-steroid hormone](http://purl.obolibrary.org/obo/CHEBI_64600) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:64600" + +- [C21-steroid hormone](http://purl.obolibrary.org/obo/CHEBI_64600) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A steroid compound with a structure based on a 21-carbon (pregnane) skeleton that acts as a hormone." + +- [C21-steroid hormone](http://purl.obolibrary.org/obo/CHEBI_64600) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [C21-steroid hormone](http://purl.obolibrary.org/obo/CHEBI_64600) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "C21-steroid hormones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [C21-steroid hormone](http://purl.obolibrary.org/obo/CHEBI_64600) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [C21-steroid hormone](http://purl.obolibrary.org/obo/CHEBI_64600) SubClassOf [steroid hormone](http://purl.obolibrary.org/obo/CHEBI_26764) + +- [C21-steroid hormone](http://purl.obolibrary.org/obo/CHEBI_64600) SubClassOf [C21-steroid](http://purl.obolibrary.org/obo/CHEBI_61313) + + + +### C21-steroid hormone biosynthetic process `http://purl.obolibrary.org/obo/GO_0006700` +#### Removed +- [C21-steroid hormone biosynthetic process](http://purl.obolibrary.org/obo/GO_0006700) SubClassOf [steroid hormone biosynthetic process](http://purl.obolibrary.org/obo/GO_0120178) + +#### Added +- [C21-steroid hormone biosynthetic process](http://purl.obolibrary.org/obo/GO_0006700) SubClassOf [steroid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006694) + + +### C21-steroid hormone catabolic process `http://purl.obolibrary.org/obo/GO_0008208` +#### Removed +- [C21-steroid hormone catabolic process](http://purl.obolibrary.org/obo/GO_0008208) SubClassOf [steroid catabolic process](http://purl.obolibrary.org/obo/GO_0006706) + + + +### CD103-negative, langerin-positive lymph node dendritic cell `http://purl.obolibrary.org/obo/CL_0002510` +#### Removed +- [CD103-negative, langerin-positive lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002510) EquivalentTo [langerin-positive lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002507) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010)) + +- [CD103-negative, langerin-positive lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002510) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010) + +#### Added +- [CD103-negative, langerin-positive lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002510) EquivalentTo [langerin-positive lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002507) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) + +- [CD103-negative, langerin-positive lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002510) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010) + + +### CD11c-low plasmacytoid dendritic cell `http://purl.obolibrary.org/obo/CL_0000989` +#### Removed +- [CD11c-low plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000989) EquivalentTo [plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000784) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) + +- [CD11c-low plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000989) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +#### Added +- [CD11c-low plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000989) EquivalentTo [plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000784) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) + +- [CD11c-low plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000989) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + + +### CD14-positive dermal dendritic cell `http://purl.obolibrary.org/obo/CL_0002526` +#### Removed +- [CD14-positive dermal dendritic cell](http://purl.obolibrary.org/obo/CL_0002526) EquivalentTo [dermal dendritic cell](http://purl.obolibrary.org/obo/CL_0001006) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [regulation of isotype switching](http://purl.obolibrary.org/obo/GO_0045191)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD1a](http://purl.obolibrary.org/obo/PR_000002025)) + +- [CD14-positive dermal dendritic cell](http://purl.obolibrary.org/obo/CL_0002526) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD1a](http://purl.obolibrary.org/obo/PR_000002025) + +#### Added +- [CD14-positive dermal dendritic cell](http://purl.obolibrary.org/obo/CL_0002526) EquivalentTo [dermal dendritic cell](http://purl.obolibrary.org/obo/CL_0001006) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD1a](http://purl.obolibrary.org/obo/PR_000002025)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [regulation of isotype switching](http://purl.obolibrary.org/obo/GO_0045191)) + +- [CD14-positive dermal dendritic cell](http://purl.obolibrary.org/obo/CL_0002526) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD1a](http://purl.obolibrary.org/obo/PR_000002025) + + +### CD14-positive monocyte `http://purl.obolibrary.org/obo/CL_0001054` +#### Removed +- [CD14-positive monocyte](http://purl.obolibrary.org/obo/CL_0001054) EquivalentTo [monocyte](http://purl.obolibrary.org/obo/CL_0000576) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) + +- [CD14-positive monocyte](http://purl.obolibrary.org/obo/CL_0001054) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [CD14-positive monocyte](http://purl.obolibrary.org/obo/CL_0001054) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [CD14-positive monocyte](http://purl.obolibrary.org/obo/CL_0001054) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +#### Added +- [CD14-positive monocyte](http://purl.obolibrary.org/obo/CL_0001054) EquivalentTo [monocyte](http://purl.obolibrary.org/obo/CL_0000576) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) + +- [CD14-positive monocyte](http://purl.obolibrary.org/obo/CL_0001054) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [CD14-positive monocyte](http://purl.obolibrary.org/obo/CL_0001054) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [CD14-positive monocyte](http://purl.obolibrary.org/obo/CL_0001054) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + + +### CD14-positive, CD16-negative classical monocyte `http://purl.obolibrary.org/obo/CL_0002057` +#### Removed +- [CD14-positive, CD16-negative classical monocyte](http://purl.obolibrary.org/obo/CL_0002057) EquivalentTo [classical monocyte](http://purl.obolibrary.org/obo/CL_0000860) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [high affinity immunoglobulin gamma Fc receptor I](http://purl.obolibrary.org/obo/PR_000001465)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [scavenger receptor cysteine-rich type 1 protein M130](http://purl.obolibrary.org/obo/PR_000001925)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) + +- [CD14-positive, CD16-negative classical monocyte](http://purl.obolibrary.org/obo/CL_0002057) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483) + +#### Added +- [CD14-positive, CD16-negative classical monocyte](http://purl.obolibrary.org/obo/CL_0002057) EquivalentTo [classical monocyte](http://purl.obolibrary.org/obo/CL_0000860) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [high affinity immunoglobulin gamma Fc receptor I](http://purl.obolibrary.org/obo/PR_000001465)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [scavenger receptor cysteine-rich type 1 protein M130](http://purl.obolibrary.org/obo/PR_000001925)) + +- [CD14-positive, CD16-negative classical monocyte](http://purl.obolibrary.org/obo/CL_0002057) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483) + + +### CD14-positive, CD16-positive monocyte `http://purl.obolibrary.org/obo/CL_0002397` +#### Removed +- [CD14-positive, CD16-positive monocyte](http://purl.obolibrary.org/obo/CL_0002397) EquivalentTo [CD14-positive monocyte](http://purl.obolibrary.org/obo/CL_0001054) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 2](http://purl.obolibrary.org/obo/PR_000001199)) + +- [CD14-positive, CD16-positive monocyte](http://purl.obolibrary.org/obo/CL_0002397) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 2](http://purl.obolibrary.org/obo/PR_000001199) + +#### Added +- [CD14-positive, CD16-positive monocyte](http://purl.obolibrary.org/obo/CL_0002397) EquivalentTo [CD14-positive monocyte](http://purl.obolibrary.org/obo/CL_0001054) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 2](http://purl.obolibrary.org/obo/PR_000001199)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) + +- [CD14-positive, CD16-positive monocyte](http://purl.obolibrary.org/obo/CL_0002397) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 2](http://purl.obolibrary.org/obo/PR_000001199) + + +### CD16-negative, CD56-bright natural killer cell, human `http://purl.obolibrary.org/obo/CL_0000938` +#### Removed +- [CD16-negative, CD56-bright natural killer cell, human](http://purl.obolibrary.org/obo/CL_0000938) EquivalentTo [mature natural killer cell](http://purl.obolibrary.org/obo/CL_0000824) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [SLAM family member 5](http://purl.obolibrary.org/obo/PR_000001319)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [type II interferon production](http://purl.obolibrary.org/obo/GO_0032609)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC class II histocompatibility antigen alpha chain DRA](http://purl.obolibrary.org/obo/PR_000002015)) + +- [CD16-negative, CD56-bright natural killer cell, human](http://purl.obolibrary.org/obo/CL_0000938) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483) + +- [CD16-negative, CD56-bright natural killer cell, human](http://purl.obolibrary.org/obo/CL_0000938) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC class II histocompatibility antigen alpha chain DRA](http://purl.obolibrary.org/obo/PR_000002015) + +#### Added +- [CD16-negative, CD56-bright natural killer cell, human](http://purl.obolibrary.org/obo/CL_0000938) EquivalentTo [mature natural killer cell](http://purl.obolibrary.org/obo/CL_0000824) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC class II histocompatibility antigen alpha chain DRA](http://purl.obolibrary.org/obo/PR_000002015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [SLAM family member 5](http://purl.obolibrary.org/obo/PR_000001319)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [type II interferon production](http://purl.obolibrary.org/obo/GO_0032609)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) + +- [CD16-negative, CD56-bright natural killer cell, human](http://purl.obolibrary.org/obo/CL_0000938) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC class II histocompatibility antigen alpha chain DRA](http://purl.obolibrary.org/obo/PR_000002015) + +- [CD16-negative, CD56-bright natural killer cell, human](http://purl.obolibrary.org/obo/CL_0000938) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483) + + +### CD16-positive, CD56-dim natural killer cell, human `http://purl.obolibrary.org/obo/CL_0000939` +#### Removed +- [CD16-positive, CD56-dim natural killer cell, human](http://purl.obolibrary.org/obo/CL_0000939) EquivalentTo [mature natural killer cell](http://purl.obolibrary.org/obo/CL_0000824) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [cytokine production](http://purl.obolibrary.org/obo/GO_0001816)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [natural killer cell mediated cytotoxicity](http://purl.obolibrary.org/obo/GO_0042267)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC class II histocompatibility antigen alpha chain DRA](http://purl.obolibrary.org/obo/PR_000002015)) + +- [CD16-positive, CD56-dim natural killer cell, human](http://purl.obolibrary.org/obo/CL_0000939) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC class II histocompatibility antigen alpha chain DRA](http://purl.obolibrary.org/obo/PR_000002015) + +#### Added +- [CD16-positive, CD56-dim natural killer cell, human](http://purl.obolibrary.org/obo/CL_0000939) EquivalentTo [mature natural killer cell](http://purl.obolibrary.org/obo/CL_0000824) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC class II histocompatibility antigen alpha chain DRA](http://purl.obolibrary.org/obo/PR_000002015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [cytokine production](http://purl.obolibrary.org/obo/GO_0001816)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [natural killer cell mediated cytotoxicity](http://purl.obolibrary.org/obo/GO_0042267)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) + +- [CD16-positive, CD56-dim natural killer cell, human](http://purl.obolibrary.org/obo/CL_0000939) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC class II histocompatibility antigen alpha chain DRA](http://purl.obolibrary.org/obo/PR_000002015) + + +### CD24-negative CD38-negative IgG-negative class switched memory B cell `http://purl.obolibrary.org/obo/CL_0002121` +#### Removed +- [CD24-negative CD38-negative IgG-negative class switched memory B cell](http://purl.obolibrary.org/obo/CL_0002121) EquivalentTo [CD38-negative IgG-negative class switched memory B cell](http://purl.obolibrary.org/obo/CL_0002118) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) + +- [CD24-negative CD38-negative IgG-negative class switched memory B cell](http://purl.obolibrary.org/obo/CL_0002121) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932) + +#### Added +- [CD24-negative CD38-negative IgG-negative class switched memory B cell](http://purl.obolibrary.org/obo/CL_0002121) EquivalentTo [CD38-negative IgG-negative class switched memory B cell](http://purl.obolibrary.org/obo/CL_0002118) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) + +- [CD24-negative CD38-negative IgG-negative class switched memory B cell](http://purl.obolibrary.org/obo/CL_0002121) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932) + + +### CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell `http://purl.obolibrary.org/obo/CL_4030038` + +#### Added +- [CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell](http://purl.obolibrary.org/obo/CL_4030038) [date](http://purl.org/dc/terms/date) "2023-03-07T14:17:39Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell](http://purl.obolibrary.org/obo/CL_4030038) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A CD24-positive, CD-133-positive, vimentin-positive cell found scattered throughout a renal proximal tubule and that may participate in tubular regeneration. Compared to other proximal tubular cell types, this cell contains less cytoplasm, fewer mitochondria and no brush border." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23124355" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21281815" + +- [CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell](http://purl.obolibrary.org/obo/CL_4030038) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "CD24+CD133+ tubular cell" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23124355" + +- [CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell](http://purl.obolibrary.org/obo/CL_4030038) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "CD24-positive tubular cell" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23124355" + +- [CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell](http://purl.obolibrary.org/obo/CL_4030038) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "After acute tubular injury, this cell type becomes more numerous. In healthy rat kidneys, this cell is not detectable, whereas after unilateral ureteral obstruction (renal injury), it may appear de novo, arguing against the notion that this cell type represents a pre-existing progenitor cell population. In at least one study, data indicate that this cell type represents transiently dedifferentiated tubular cells involved in regeneration." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23124355" + +- [CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell](http://purl.obolibrary.org/obo/CL_4030038) [label](http://www.w3.org/2000/01/rdf-schema#label) "CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell" + +- [CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell](http://purl.obolibrary.org/obo/CL_4030038) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "CD133+CD24+CD106- tubular cell" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://doi.org/10.1002/stem.1130" + +- Class: [CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell](http://purl.obolibrary.org/obo/CL_4030038) + +- [CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell](http://purl.obolibrary.org/obo/CL_4030038) SubClassOf [expresses](http://purl.obolibrary.org/obo/RO_0002292) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932) + +- [CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell](http://purl.obolibrary.org/obo/CL_4030038) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [proximal tubular epithelium](http://purl.obolibrary.org/obo/UBERON_0008404) + +- [CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell](http://purl.obolibrary.org/obo/CL_4030038) SubClassOf [epithelial cell of proximal tubule](http://purl.obolibrary.org/obo/CL_0002306) + +- [CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell](http://purl.obolibrary.org/obo/CL_4030038) SubClassOf [expresses](http://purl.obolibrary.org/obo/RO_0002292) some [prominin-1](http://purl.obolibrary.org/obo/PR_000001786) + + +### CD25+ mast cell `http://purl.obolibrary.org/obo/CL_0011023` + +#### Added +- [CD25+ mast cell](http://purl.obolibrary.org/obo/CL_0011023) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + + +### CD27-negative gamma-delta T cell `http://purl.obolibrary.org/obo/CL_0002125` +#### Removed +- [CD27-negative gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0002125) EquivalentTo [mature gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000800) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nuclear receptor ROR-gamma isoform 2](http://purl.obolibrary.org/obo/PR_000003455)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-17 production](http://purl.obolibrary.org/obo/GO_0032620)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) + +- [CD27-negative gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0002125) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963) + +#### Added +- [CD27-negative gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0002125) EquivalentTo [mature gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000800) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nuclear receptor ROR-gamma isoform 2](http://purl.obolibrary.org/obo/PR_000003455)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-17 production](http://purl.obolibrary.org/obo/GO_0032620)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) + +- [CD27-negative gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0002125) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963) + + +### CD34-negative, CD117-positive innate lymphoid cell, human `http://purl.obolibrary.org/obo/CL_0001072` +#### Removed +- [CD34-negative, CD117-positive innate lymphoid cell, human](http://purl.obolibrary.org/obo/CL_0001072) EquivalentTo [innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001065) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [immature](http://purl.obolibrary.org/obo/PATO_0001501)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor Kit (human)](http://purl.obolibrary.org/obo/PR_P10721)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [hematopoietic progenitor cell antigen CD34 (human)](http://purl.obolibrary.org/obo/PR_P28906)) + +- [CD34-negative, CD117-positive innate lymphoid cell, human](http://purl.obolibrary.org/obo/CL_0001072) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [hematopoietic progenitor cell antigen CD34 (human)](http://purl.obolibrary.org/obo/PR_P28906) + +#### Added +- [CD34-negative, CD117-positive innate lymphoid cell, human](http://purl.obolibrary.org/obo/CL_0001072) EquivalentTo [innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001065) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [hematopoietic progenitor cell antigen CD34 (human)](http://purl.obolibrary.org/obo/PR_P28906)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [immature](http://purl.obolibrary.org/obo/PATO_0001501)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor Kit (human)](http://purl.obolibrary.org/obo/PR_P10721)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) + +- [CD34-negative, CD117-positive innate lymphoid cell, human](http://purl.obolibrary.org/obo/CL_0001072) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [hematopoietic progenitor cell antigen CD34 (human)](http://purl.obolibrary.org/obo/PR_P28906) + + +### CD34-negative, CD41-positive, CD42-positive megakaryocyte cell `http://purl.obolibrary.org/obo/CL_0002026` +#### Removed +- [CD34-negative, CD41-positive, CD42-positive megakaryocyte cell](http://purl.obolibrary.org/obo/CL_0002026) EquivalentTo [megakaryocyte](http://purl.obolibrary.org/obo/CL_0000556) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [platelet glycoprotein Ib alpha chain](http://purl.obolibrary.org/obo/PR_000001907)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-IIb](http://purl.obolibrary.org/obo/PR_000009127)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) + +- [CD34-negative, CD41-positive, CD42-positive megakaryocyte cell](http://purl.obolibrary.org/obo/CL_0002026) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + +#### Added +- [CD34-negative, CD41-positive, CD42-positive megakaryocyte cell](http://purl.obolibrary.org/obo/CL_0002026) EquivalentTo [megakaryocyte](http://purl.obolibrary.org/obo/CL_0000556) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [platelet glycoprotein Ib alpha chain](http://purl.obolibrary.org/obo/PR_000001907)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-IIb](http://purl.obolibrary.org/obo/PR_000009127)) + +- [CD34-negative, CD41-positive, CD42-positive megakaryocyte cell](http://purl.obolibrary.org/obo/CL_0002026) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + +- [CD34-negative, CD41-positive, CD42-positive megakaryocyte cell](http://purl.obolibrary.org/obo/CL_0002026) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + + +### CD34-negative, GlyA-negative proerythroblast `http://purl.obolibrary.org/obo/CL_0002004` +#### Removed +- [CD34-negative, GlyA-negative proerythroblast](http://purl.obolibrary.org/obo/CL_0002004) EquivalentTo [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [glycophorin-A](http://purl.obolibrary.org/obo/PR_000001460)) + +- [CD34-negative, GlyA-negative proerythroblast](http://purl.obolibrary.org/obo/CL_0002004) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + +- [CD34-negative, GlyA-negative proerythroblast](http://purl.obolibrary.org/obo/CL_0002004) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [glycophorin-A](http://purl.obolibrary.org/obo/PR_000001460) + +#### Added +- [CD34-negative, GlyA-negative proerythroblast](http://purl.obolibrary.org/obo/CL_0002004) EquivalentTo [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [glycophorin-A](http://purl.obolibrary.org/obo/PR_000001460)) + +- [CD34-negative, GlyA-negative proerythroblast](http://purl.obolibrary.org/obo/CL_0002004) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [glycophorin-A](http://purl.obolibrary.org/obo/PR_000001460) + +- [CD34-negative, GlyA-negative proerythroblast](http://purl.obolibrary.org/obo/CL_0002004) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + + +### CD34-positive, CD38-negative hematopoietic stem cell `http://purl.obolibrary.org/obo/CL_0001024` +#### Removed +- [CD34-positive, CD38-negative hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001024) EquivalentTo [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [prominin-1](http://purl.obolibrary.org/obo/PR_000001786)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD59-like glycoprotein](http://purl.obolibrary.org/obo/PR_000001809)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [Thy-1 membrane glycoprotein](http://purl.obolibrary.org/obo/PR_000001843)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD33 molecule](http://purl.obolibrary.org/obo/PR_000001892)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) + +- [CD34-positive, CD38-negative hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001024) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483) + +- [CD34-positive, CD38-negative hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001024) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + +- [CD34-positive, CD38-negative hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001024) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD33 molecule](http://purl.obolibrary.org/obo/PR_000001892) + +- [CD34-positive, CD38-negative hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001024) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945) + +#### Added +- [CD34-positive, CD38-negative hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001024) EquivalentTo [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD33 molecule](http://purl.obolibrary.org/obo/PR_000001892)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [prominin-1](http://purl.obolibrary.org/obo/PR_000001786)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD59-like glycoprotein](http://purl.obolibrary.org/obo/PR_000001809)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [Thy-1 membrane glycoprotein](http://purl.obolibrary.org/obo/PR_000001843)) + +- [CD34-positive, CD38-negative hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001024) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD33 molecule](http://purl.obolibrary.org/obo/PR_000001892) + +- [CD34-positive, CD38-negative hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001024) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945) + +- [CD34-positive, CD38-negative hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001024) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483) + +- [CD34-positive, CD38-negative hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001024) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + + +### CD34-positive, CD38-negative multipotent progenitor cell `http://purl.obolibrary.org/obo/CL_0002043` +#### Removed +- [CD34-positive, CD38-negative multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002043) EquivalentTo [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [Thy-1 membrane glycoprotein](http://purl.obolibrary.org/obo/PR_000001843)) + +- [CD34-positive, CD38-negative multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002043) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + +- [CD34-positive, CD38-negative multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002043) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + +- [CD34-positive, CD38-negative multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002043) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [Thy-1 membrane glycoprotein](http://purl.obolibrary.org/obo/PR_000001843) + +#### Added +- [CD34-positive, CD38-negative multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002043) EquivalentTo [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [Thy-1 membrane glycoprotein](http://purl.obolibrary.org/obo/PR_000001843)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) + +- [CD34-positive, CD38-negative multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002043) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + +- [CD34-positive, CD38-negative multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002043) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [Thy-1 membrane glycoprotein](http://purl.obolibrary.org/obo/PR_000001843) + +- [CD34-positive, CD38-negative multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002043) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + + +### CD34-positive, CD38-positive common myeloid progenitor `http://purl.obolibrary.org/obo/CL_0001026` +#### Removed +- [CD34-positive, CD38-positive common myeloid progenitor](http://purl.obolibrary.org/obo/CL_0001026) EquivalentTo [common myeloid progenitor, CD34-positive](http://purl.obolibrary.org/obo/CL_0001059) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD7 molecule](http://purl.obolibrary.org/obo/PR_000001836)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-5 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001867)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neprilysin](http://purl.obolibrary.org/obo/PR_000001898)) + +- [CD34-positive, CD38-positive common myeloid progenitor](http://purl.obolibrary.org/obo/CL_0001026) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD7 molecule](http://purl.obolibrary.org/obo/PR_000001836) + +- [CD34-positive, CD38-positive common myeloid progenitor](http://purl.obolibrary.org/obo/CL_0001026) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-5 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001867) + +- [CD34-positive, CD38-positive common myeloid progenitor](http://purl.obolibrary.org/obo/CL_0001026) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + +- [CD34-positive, CD38-positive common myeloid progenitor](http://purl.obolibrary.org/obo/CL_0001026) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neprilysin](http://purl.obolibrary.org/obo/PR_000001898) + +#### Added +- [CD34-positive, CD38-positive common myeloid progenitor](http://purl.obolibrary.org/obo/CL_0001026) EquivalentTo [common myeloid progenitor, CD34-positive](http://purl.obolibrary.org/obo/CL_0001059) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD7 molecule](http://purl.obolibrary.org/obo/PR_000001836)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-5 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001867)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neprilysin](http://purl.obolibrary.org/obo/PR_000001898)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) + +- [CD34-positive, CD38-positive common myeloid progenitor](http://purl.obolibrary.org/obo/CL_0001026) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-5 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001867) + +- [CD34-positive, CD38-positive common myeloid progenitor](http://purl.obolibrary.org/obo/CL_0001026) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neprilysin](http://purl.obolibrary.org/obo/PR_000001898) + +- [CD34-positive, CD38-positive common myeloid progenitor](http://purl.obolibrary.org/obo/CL_0001026) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD7 molecule](http://purl.obolibrary.org/obo/PR_000001836) + +- [CD34-positive, CD38-positive common myeloid progenitor](http://purl.obolibrary.org/obo/CL_0001026) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + + +### CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell `http://purl.obolibrary.org/obo/CL_0002005` +#### Removed +- [CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002005) EquivalentTo [megakaryocyte-erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0000050) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) + +- [CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002005) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865) + +- [CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002005) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + +#### Added +- [CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002005) EquivalentTo [megakaryocyte-erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0000050) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) + +- [CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002005) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865) + +- [CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002005) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + + +### CD34-positive, CD41-positive, CD42-negative megakaryocyte progenitor cell `http://purl.obolibrary.org/obo/CL_0002025` +#### Removed +- [CD34-positive, CD41-positive, CD42-negative megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0002025) EquivalentTo [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-IIb](http://purl.obolibrary.org/obo/PR_000009127)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [platelet glycoprotein Ib alpha chain](http://purl.obolibrary.org/obo/PR_000001907)) + +- [CD34-positive, CD41-positive, CD42-negative megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0002025) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [platelet glycoprotein Ib alpha chain](http://purl.obolibrary.org/obo/PR_000001907) + +#### Added +- [CD34-positive, CD41-positive, CD42-negative megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0002025) EquivalentTo [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [platelet glycoprotein Ib alpha chain](http://purl.obolibrary.org/obo/PR_000001907)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-IIb](http://purl.obolibrary.org/obo/PR_000009127)) + +- [CD34-positive, CD41-positive, CD42-negative megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0002025) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [platelet glycoprotein Ib alpha chain](http://purl.obolibrary.org/obo/PR_000001907) + + +### CD34-positive, GlyA-negative erythroid progenitor cell `http://purl.obolibrary.org/obo/CL_0002003` +#### Removed +- [CD34-positive, GlyA-negative erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002003) EquivalentTo [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [glycophorin-A](http://purl.obolibrary.org/obo/PR_000001460)) + +- [CD34-positive, GlyA-negative erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002003) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [glycophorin-A](http://purl.obolibrary.org/obo/PR_000001460) + +#### Added +- [CD34-positive, GlyA-negative erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002003) EquivalentTo [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [glycophorin-A](http://purl.obolibrary.org/obo/PR_000001460)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) + +- [CD34-positive, GlyA-negative erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002003) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [glycophorin-A](http://purl.obolibrary.org/obo/PR_000001460) + + +### CD38-negative IgG memory B cell `http://purl.obolibrary.org/obo/CL_0002108` +#### Removed +- [CD38-negative IgG memory B cell](http://purl.obolibrary.org/obo/CL_0002108) EquivalentTo [IgG memory B cell](http://purl.obolibrary.org/obo/CL_0000979) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) + +- [CD38-negative IgG memory B cell](http://purl.obolibrary.org/obo/CL_0002108) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + +#### Added +- [CD38-negative IgG memory B cell](http://purl.obolibrary.org/obo/CL_0002108) EquivalentTo [IgG memory B cell](http://purl.obolibrary.org/obo/CL_0000979) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) + +- [CD38-negative IgG memory B cell](http://purl.obolibrary.org/obo/CL_0002108) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + + +### CD38-negative IgG-negative class switched memory B cell `http://purl.obolibrary.org/obo/CL_0002118` +#### Removed +- [CD38-negative IgG-negative class switched memory B cell](http://purl.obolibrary.org/obo/CL_0002118) EquivalentTo [IgG-negative class switched memory B cell](http://purl.obolibrary.org/obo/CL_0002117) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) + +- [CD38-negative IgG-negative class switched memory B cell](http://purl.obolibrary.org/obo/CL_0002118) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + +#### Added +- [CD38-negative IgG-negative class switched memory B cell](http://purl.obolibrary.org/obo/CL_0002118) EquivalentTo [IgG-negative class switched memory B cell](http://purl.obolibrary.org/obo/CL_0002117) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) + +- [CD38-negative IgG-negative class switched memory B cell](http://purl.obolibrary.org/obo/CL_0002118) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + + +### CD38-negative immature B cell `http://purl.obolibrary.org/obo/CL_0002055` +#### Removed +- [CD38-negative immature B cell](http://purl.obolibrary.org/obo/CL_0002055) EquivalentTo [immature B cell](http://purl.obolibrary.org/obo/CL_0000816) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [B-cell receptor CD22](http://purl.obolibrary.org/obo/PR_000001288)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [neprilysin](http://purl.obolibrary.org/obo/PR_000001898)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) + +- [CD38-negative immature B cell](http://purl.obolibrary.org/obo/CL_0002055) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + +#### Added +- [CD38-negative immature B cell](http://purl.obolibrary.org/obo/CL_0002055) EquivalentTo [immature B cell](http://purl.obolibrary.org/obo/CL_0000816) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [B-cell receptor CD22](http://purl.obolibrary.org/obo/PR_000001288)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [neprilysin](http://purl.obolibrary.org/obo/PR_000001898)) + +- [CD38-negative immature B cell](http://purl.obolibrary.org/obo/CL_0002055) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + + +### CD38-negative naive B cell `http://purl.obolibrary.org/obo/CL_0002102` +#### Removed +- [CD38-negative naive B cell](http://purl.obolibrary.org/obo/CL_0002102) EquivalentTo [naive B cell](http://purl.obolibrary.org/obo/CL_0000788) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) + +- [CD38-negative naive B cell](http://purl.obolibrary.org/obo/CL_0002102) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + +#### Added +- [CD38-negative naive B cell](http://purl.obolibrary.org/obo/CL_0002102) EquivalentTo [naive B cell](http://purl.obolibrary.org/obo/CL_0000788) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) + +- [CD38-negative naive B cell](http://purl.obolibrary.org/obo/CL_0002102) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + + +### CD38-negative unswitched memory B cell `http://purl.obolibrary.org/obo/CL_0002111` +#### Removed +- [CD38-negative unswitched memory B cell](http://purl.obolibrary.org/obo/CL_0002111) EquivalentTo [unswitched memory B cell](http://purl.obolibrary.org/obo/CL_0000970) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) + +- [CD38-negative unswitched memory B cell](http://purl.obolibrary.org/obo/CL_0002111) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + +#### Added +- [CD38-negative unswitched memory B cell](http://purl.obolibrary.org/obo/CL_0002111) EquivalentTo [unswitched memory B cell](http://purl.obolibrary.org/obo/CL_0000970) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) + +- [CD38-negative unswitched memory B cell](http://purl.obolibrary.org/obo/CL_0002111) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + + +### CD4 biosynthetic process `http://purl.obolibrary.org/obo/GO_0045222` + +#### Added +- [CD4 biosynthetic process](http://purl.obolibrary.org/obo/GO_0045222) SubClassOf [protein metabolic process](http://purl.obolibrary.org/obo/GO_0019538) + + +### CD4-negative CD8-negative gamma-delta intraepithelial T cell `http://purl.obolibrary.org/obo/CL_0000803` +#### Removed +- [CD4-negative CD8-negative gamma-delta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000803) EquivalentTo [gamma-delta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000801) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +- [CD4-negative CD8-negative gamma-delta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000803) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [CD4-negative CD8-negative gamma-delta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000803) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +#### Added +- [CD4-negative CD8-negative gamma-delta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000803) EquivalentTo [gamma-delta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000801) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +- [CD4-negative CD8-negative gamma-delta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000803) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [CD4-negative CD8-negative gamma-delta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000803) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + + +### CD4-negative, CD8-negative type I NK T cell `http://purl.obolibrary.org/obo/CL_0000924` +#### Removed +- [CD4-negative, CD8-negative type I NK T cell](http://purl.obolibrary.org/obo/CL_0000924) EquivalentTo [type I NK T cell](http://purl.obolibrary.org/obo/CL_0000921) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +- [CD4-negative, CD8-negative type I NK T cell](http://purl.obolibrary.org/obo/CL_0000924) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [CD4-negative, CD8-negative type I NK T cell](http://purl.obolibrary.org/obo/CL_0000924) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +#### Added +- [CD4-negative, CD8-negative type I NK T cell](http://purl.obolibrary.org/obo/CL_0000924) EquivalentTo [type I NK T cell](http://purl.obolibrary.org/obo/CL_0000921) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +- [CD4-negative, CD8-negative type I NK T cell](http://purl.obolibrary.org/obo/CL_0000924) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [CD4-negative, CD8-negative type I NK T cell](http://purl.obolibrary.org/obo/CL_0000924) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + + +### CD4-negative, CD8-negative type I NK T cell secreting interferon-gamma `http://purl.obolibrary.org/obo/CL_0000929` +#### Removed +- [CD4-negative, CD8-negative type I NK T cell secreting interferon-gamma](http://purl.obolibrary.org/obo/CL_0000929) EquivalentTo [type I NK T cell](http://purl.obolibrary.org/obo/CL_0000921) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of T-helper 1 type immune response](http://purl.obolibrary.org/obo/GO_0002827)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [type II interferon production](http://purl.obolibrary.org/obo/GO_0032609)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +#### Added +- [CD4-negative, CD8-negative type I NK T cell secreting interferon-gamma](http://purl.obolibrary.org/obo/CL_0000929) EquivalentTo [type I NK T cell](http://purl.obolibrary.org/obo/CL_0000921) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of T-helper 1 type immune response](http://purl.obolibrary.org/obo/GO_0002827)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [type II interferon production](http://purl.obolibrary.org/obo/GO_0032609)) + + +### CD4-negative, CD8-negative type I NK T cell secreting interleukin-4 `http://purl.obolibrary.org/obo/CL_0000930` +#### Removed +- [CD4-negative, CD8-negative type I NK T cell secreting interleukin-4](http://purl.obolibrary.org/obo/CL_0000930) EquivalentTo [type I NK T cell](http://purl.obolibrary.org/obo/CL_0000921) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of type 2 immune response](http://purl.obolibrary.org/obo/GO_0002830)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-4 production](http://purl.obolibrary.org/obo/GO_0032633)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +#### Added +- [CD4-negative, CD8-negative type I NK T cell secreting interleukin-4](http://purl.obolibrary.org/obo/CL_0000930) EquivalentTo [type I NK T cell](http://purl.obolibrary.org/obo/CL_0000921) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of type 2 immune response](http://purl.obolibrary.org/obo/GO_0002830)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-4 production](http://purl.obolibrary.org/obo/GO_0032633)) + + +### CD4-negative, CD8-negative, alpha-beta intraepithelial T cell `http://purl.obolibrary.org/obo/CL_0000935` +#### Removed +- [CD4-negative, CD8-negative, alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000935) EquivalentTo [alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000797) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain isoform 1](http://purl.obolibrary.org/obo/PR_000025403)) + +- [CD4-negative, CD8-negative, alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000935) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [CD4-negative, CD8-negative, alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000935) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain isoform 1](http://purl.obolibrary.org/obo/PR_000025403) + +#### Added +- [CD4-negative, CD8-negative, alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000935) EquivalentTo [alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000797) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain isoform 1](http://purl.obolibrary.org/obo/PR_000025403)) + +- [CD4-negative, CD8-negative, alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000935) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain isoform 1](http://purl.obolibrary.org/obo/PR_000025403) + +- [CD4-negative, CD8-negative, alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000935) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + + +### CD4-positive CD11b-positive dendritic cell `http://purl.obolibrary.org/obo/CL_0000999` +#### Removed +- [CD4-positive CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0000999) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [cytokine production](http://purl.obolibrary.org/obo/GO_0001816)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [negative regulation of inflammatory response](http://purl.obolibrary.org/obo/GO_0050728)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 75](http://purl.obolibrary.org/obo/PR_000001026)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +- [CD4-positive CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0000999) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 75](http://purl.obolibrary.org/obo/PR_000001026) + +- [CD4-positive CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0000999) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +#### Added +- [CD4-positive CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0000999) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 75](http://purl.obolibrary.org/obo/PR_000001026)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [cytokine production](http://purl.obolibrary.org/obo/GO_0001816)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [negative regulation of inflammatory response](http://purl.obolibrary.org/obo/GO_0050728)) + +- [CD4-positive CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0000999) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 75](http://purl.obolibrary.org/obo/PR_000001026) + +- [CD4-positive CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0000999) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + + +### CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0001051` +#### Removed +- [CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001051) EquivalentTo [CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000624) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207)) + +- [CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001051) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202) + +- [CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001051) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207) + +#### Added +- [CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001051) EquivalentTo [CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000624) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207)) + +- [CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001051) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207) + +- [CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001051) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202) + + +### CD4-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000624` +#### Removed +- [CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000624) EquivalentTo [mature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000791) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) + +- [CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000624) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402) + +#### Added +- [CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000624) EquivalentTo [mature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000791) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) + +- [CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000624) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402) + + +### CD4-positive, alpha-beta memory T cell, CD45RO-positive `http://purl.obolibrary.org/obo/CL_0001204` +#### Removed +- [CD4-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001204) EquivalentTo [CD4-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000897) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [interleukin-2 receptor subunit beta](http://purl.obolibrary.org/obo/PR_000001381)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) + +- [CD4-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001204) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + +#### Added +- [CD4-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001204) EquivalentTo [CD4-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000897) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [interleukin-2 receptor subunit beta](http://purl.obolibrary.org/obo/PR_000001381)) + +- [CD4-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001204) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + + +### CD4-positive, alpha-beta thymocyte `http://purl.obolibrary.org/obo/CL_0000810` +#### Removed +- [CD4-positive, alpha-beta thymocyte](http://purl.obolibrary.org/obo/CL_0000810) EquivalentTo [immature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000790) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [thymus](http://purl.obolibrary.org/obo/UBERON_0002370)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +- [CD4-positive, alpha-beta thymocyte](http://purl.obolibrary.org/obo/CL_0000810) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +#### Added +- [CD4-positive, alpha-beta thymocyte](http://purl.obolibrary.org/obo/CL_0000810) EquivalentTo [immature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000790) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [thymus](http://purl.obolibrary.org/obo/UBERON_0002370)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) + +- [CD4-positive, alpha-beta thymocyte](http://purl.obolibrary.org/obo/CL_0000810) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + + +### CD56-negative, CD161-positive immature natural killer cell, human `http://purl.obolibrary.org/obo/CL_0002344` +#### Removed +- [CD56-negative, CD161-positive immature natural killer cell, human](http://purl.obolibrary.org/obo/CL_0002344) EquivalentTo [immature natural killer cell](http://purl.obolibrary.org/obo/CL_0000823) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit beta](http://purl.obolibrary.org/obo/PR_000001381)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) + +- [CD56-negative, CD161-positive immature natural killer cell, human](http://purl.obolibrary.org/obo/CL_0002344) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [CD56-negative, CD161-positive immature natural killer cell, human](http://purl.obolibrary.org/obo/CL_0002344) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + +#### Added +- [CD56-negative, CD161-positive immature natural killer cell, human](http://purl.obolibrary.org/obo/CL_0002344) EquivalentTo [immature natural killer cell](http://purl.obolibrary.org/obo/CL_0000823) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit beta](http://purl.obolibrary.org/obo/PR_000001381)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) + +- [CD56-negative, CD161-positive immature natural killer cell, human](http://purl.obolibrary.org/obo/CL_0002344) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + +- [CD56-negative, CD161-positive immature natural killer cell, human](http://purl.obolibrary.org/obo/CL_0002344) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + + +### CD56-positive, CD161-positive immature natural killer cell, human `http://purl.obolibrary.org/obo/CL_0002338` +#### Removed +- [CD56-positive, CD161-positive immature natural killer cell, human](http://purl.obolibrary.org/obo/CL_0002338) EquivalentTo [immature natural killer cell](http://purl.obolibrary.org/obo/CL_0000823) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit beta](http://purl.obolibrary.org/obo/PR_000001381)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) + +- [CD56-positive, CD161-positive immature natural killer cell, human](http://purl.obolibrary.org/obo/CL_0002338) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + +#### Added +- [CD56-positive, CD161-positive immature natural killer cell, human](http://purl.obolibrary.org/obo/CL_0002338) EquivalentTo [immature natural killer cell](http://purl.obolibrary.org/obo/CL_0000823) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit beta](http://purl.obolibrary.org/obo/PR_000001381)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) + +- [CD56-positive, CD161-positive immature natural killer cell, human](http://purl.obolibrary.org/obo/CL_0002338) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + + +### CD7-negative lymphoid progenitor cell `http://purl.obolibrary.org/obo/CL_0001027` +#### Removed +- [CD7-negative lymphoid progenitor cell](http://purl.obolibrary.org/obo/CL_0001027) EquivalentTo [common lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0000051) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD7 molecule](http://purl.obolibrary.org/obo/PR_000001836)) + +- [CD7-negative lymphoid progenitor cell](http://purl.obolibrary.org/obo/CL_0001027) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD7 molecule](http://purl.obolibrary.org/obo/PR_000001836) + +- [CD7-negative lymphoid progenitor cell](http://purl.obolibrary.org/obo/CL_0001027) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + +#### Added +- [CD7-negative lymphoid progenitor cell](http://purl.obolibrary.org/obo/CL_0001027) EquivalentTo [common lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0000051) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD7 molecule](http://purl.obolibrary.org/obo/PR_000001836)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) + +- [CD7-negative lymphoid progenitor cell](http://purl.obolibrary.org/obo/CL_0001027) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD7 molecule](http://purl.obolibrary.org/obo/PR_000001836) + +- [CD7-negative lymphoid progenitor cell](http://purl.obolibrary.org/obo/CL_0001027) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + + +### CD7-positive lymphoid progenitor cell `http://purl.obolibrary.org/obo/CL_0001028` +#### Removed +- [CD7-positive lymphoid progenitor cell](http://purl.obolibrary.org/obo/CL_0001028) EquivalentTo [common lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0000051) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD7 molecule](http://purl.obolibrary.org/obo/PR_000001836)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) + +- [CD7-positive lymphoid progenitor cell](http://purl.obolibrary.org/obo/CL_0001028) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + +#### Added +- [CD7-positive lymphoid progenitor cell](http://purl.obolibrary.org/obo/CL_0001028) EquivalentTo [common lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0000051) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD7 molecule](http://purl.obolibrary.org/obo/PR_000001836)) + +- [CD7-positive lymphoid progenitor cell](http://purl.obolibrary.org/obo/CL_0001028) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + + +### CD71-negative, GlyA-positive orthochromatic erythroblast `http://purl.obolibrary.org/obo/CL_0002018` +#### Removed +- [CD71-negative, GlyA-positive orthochromatic erythroblast](http://purl.obolibrary.org/obo/CL_0002018) EquivalentTo [orthochromatic erythroblast](http://purl.obolibrary.org/obo/CL_0000552) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [glycophorin-A](http://purl.obolibrary.org/obo/PR_000001460)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) + +- [CD71-negative, GlyA-positive orthochromatic erythroblast](http://purl.obolibrary.org/obo/CL_0002018) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945) + +#### Added +- [CD71-negative, GlyA-positive orthochromatic erythroblast](http://purl.obolibrary.org/obo/CL_0002018) EquivalentTo [orthochromatic erythroblast](http://purl.obolibrary.org/obo/CL_0000552) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [glycophorin-A](http://purl.obolibrary.org/obo/PR_000001460)) + +- [CD71-negative, GlyA-positive orthochromatic erythroblast](http://purl.obolibrary.org/obo/CL_0002018) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945) + + +### CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell `http://purl.obolibrary.org/obo/CL_0000915` +#### Removed +- [CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000915) EquivalentTo [alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000797) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) + +- [CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000915) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000915) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +#### Added +- [CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000915) EquivalentTo [alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000797) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +- [CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000915) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000915) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + + +### CD8-positive, CD28-negative, alpha-beta regulatory T cell `http://purl.obolibrary.org/obo/CL_0000920` +#### Removed +- [CD8-positive, CD28-negative, alpha-beta regulatory T cell](http://purl.obolibrary.org/obo/CL_0000920) EquivalentTo [CD8-positive, alpha-beta regulatory T cell](http://purl.obolibrary.org/obo/CL_0000795) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [forkhead box protein P3](http://purl.obolibrary.org/obo/PR_000001350)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell-specific surface glycoprotein CD28](http://purl.obolibrary.org/obo/PR_000001841)) + +- [CD8-positive, CD28-negative, alpha-beta regulatory T cell](http://purl.obolibrary.org/obo/CL_0000920) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell-specific surface glycoprotein CD28](http://purl.obolibrary.org/obo/PR_000001841) + +#### Added +- [CD8-positive, CD28-negative, alpha-beta regulatory T cell](http://purl.obolibrary.org/obo/CL_0000920) EquivalentTo [CD8-positive, alpha-beta regulatory T cell](http://purl.obolibrary.org/obo/CL_0000795) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [forkhead box protein P3](http://purl.obolibrary.org/obo/PR_000001350)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell-specific surface glycoprotein CD28](http://purl.obolibrary.org/obo/PR_000001841)) + +- [CD8-positive, CD28-negative, alpha-beta regulatory T cell](http://purl.obolibrary.org/obo/CL_0000920) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell-specific surface glycoprotein CD28](http://purl.obolibrary.org/obo/PR_000001841) + + +### CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0001052` +#### Removed +- [CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001052) EquivalentTo [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207)) + +- [CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001052) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202) + +- [CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001052) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207) + +#### Added +- [CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001052) EquivalentTo [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207)) + +- [CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001052) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207) + +- [CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001052) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202) + + +### CD8-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000625` +#### Removed +- [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) EquivalentTo [mature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000791) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) + +- [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +#### Added +- [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) EquivalentTo [mature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000791) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) + +- [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + + +### CD8-positive, alpha-beta cytokine secreting effector T cell `http://purl.obolibrary.org/obo/CL_0000908` +#### Removed +- [CD8-positive, alpha-beta cytokine secreting effector T cell](http://purl.obolibrary.org/obo/CL_0000908) EquivalentTo [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD69 molecule](http://purl.obolibrary.org/obo/PR_000001343)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [cytokine production](http://purl.obolibrary.org/obo/GO_0001816)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) + +- [CD8-positive, alpha-beta cytokine secreting effector T cell](http://purl.obolibrary.org/obo/CL_0000908) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318) + +- [CD8-positive, alpha-beta cytokine secreting effector T cell](http://purl.obolibrary.org/obo/CL_0000908) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +#### Added +- [CD8-positive, alpha-beta cytokine secreting effector T cell](http://purl.obolibrary.org/obo/CL_0000908) EquivalentTo [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD69 molecule](http://purl.obolibrary.org/obo/PR_000001343)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [cytokine production](http://purl.obolibrary.org/obo/GO_0001816)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) + +- [CD8-positive, alpha-beta cytokine secreting effector T cell](http://purl.obolibrary.org/obo/CL_0000908) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318) + +- [CD8-positive, alpha-beta cytokine secreting effector T cell](http://purl.obolibrary.org/obo/CL_0000908) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + + +### CD8-positive, alpha-beta memory T cell, CD45RO-positive `http://purl.obolibrary.org/obo/CL_0001203` +#### Removed +- [CD8-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001203) EquivalentTo [CD8-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000909) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [interleukin-2 receptor subunit beta](http://purl.obolibrary.org/obo/PR_000001381)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) + +- [CD8-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001203) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + +#### Added +- [CD8-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001203) EquivalentTo [CD8-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000909) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [interleukin-2 receptor subunit beta](http://purl.obolibrary.org/obo/PR_000001381)) + +- [CD8-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001203) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + + +### CD8-positive, alpha-beta thymocyte `http://purl.obolibrary.org/obo/CL_0000811` +#### Removed +- [CD8-positive, alpha-beta thymocyte](http://purl.obolibrary.org/obo/CL_0000811) EquivalentTo [immature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000790) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [thymus](http://purl.obolibrary.org/obo/UBERON_0002370)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) + +- [CD8-positive, alpha-beta thymocyte](http://purl.obolibrary.org/obo/CL_0000811) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +#### Added +- [CD8-positive, alpha-beta thymocyte](http://purl.obolibrary.org/obo/CL_0000811) EquivalentTo [immature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000790) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [thymus](http://purl.obolibrary.org/obo/UBERON_0002370)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) + +- [CD8-positive, alpha-beta thymocyte](http://purl.obolibrary.org/obo/CL_0000811) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + + +### CD8_alpha-negative CD11b-negative dendritic cell `http://purl.obolibrary.org/obo/CL_0000998` +#### Removed +- [CD8_alpha-negative CD11b-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0000998) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 75](http://purl.obolibrary.org/obo/PR_000001026)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [antigen processing and presentation of peptide antigen via MHC class I](http://purl.obolibrary.org/obo/GO_0002474)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +- [CD8_alpha-negative CD11b-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0000998) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [CD8_alpha-negative CD11b-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0000998) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [CD8_alpha-negative CD11b-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0000998) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +#### Added +- [CD8_alpha-negative CD11b-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0000998) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 75](http://purl.obolibrary.org/obo/PR_000001026)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [antigen processing and presentation of peptide antigen via MHC class I](http://purl.obolibrary.org/obo/GO_0002474)) + +- [CD8_alpha-negative CD11b-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0000998) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [CD8_alpha-negative CD11b-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0000998) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [CD8_alpha-negative CD11b-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0000998) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + + +### CD8_alpha-negative plasmacytoid dendritic cell `http://purl.obolibrary.org/obo/CL_0002455` +#### Removed +- [CD8_alpha-negative plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0002455) EquivalentTo [CD11c-low plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000989) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +- [CD8_alpha-negative plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0002455) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +#### Added +- [CD8_alpha-negative plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0002455) EquivalentTo [CD11c-low plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000989) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) + +- [CD8_alpha-negative plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0002455) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + + +### CD8_alpha-positive CD11b-negative dendritic cell `http://purl.obolibrary.org/obo/CL_0001000` +#### Removed +- [CD8_alpha-positive CD11b-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0001000) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 75](http://purl.obolibrary.org/obo/PR_000001026)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [cytokine production](http://purl.obolibrary.org/obo/GO_0001816)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [antigen processing and presentation of exogenous peptide antigen via MHC class I](http://purl.obolibrary.org/obo/GO_0042590)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of inflammatory response](http://purl.obolibrary.org/obo/GO_0050729)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) + +- [CD8_alpha-positive CD11b-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0001000) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [CD8_alpha-positive CD11b-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0001000) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +#### Added +- [CD8_alpha-positive CD11b-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0001000) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 75](http://purl.obolibrary.org/obo/PR_000001026)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [cytokine production](http://purl.obolibrary.org/obo/GO_0001816)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [antigen processing and presentation of exogenous peptide antigen via MHC class I](http://purl.obolibrary.org/obo/GO_0042590)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of inflammatory response](http://purl.obolibrary.org/obo/GO_0050729)) + +- [CD8_alpha-positive CD11b-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0001000) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [CD8_alpha-positive CD11b-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0001000) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + + +### CD8alpha-negative thymic conventional dendritic cell `http://purl.obolibrary.org/obo/CL_0002460` +#### Removed +- [CD8alpha-negative thymic conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002460) EquivalentTo [thymic conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000941) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +- [CD8alpha-negative thymic conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002460) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +#### Added +- [CD8alpha-negative thymic conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002460) EquivalentTo [thymic conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000941) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +- [CD8alpha-negative thymic conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002460) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + + +### CD9-positive, CD41-positive megakaryocyte cell `http://purl.obolibrary.org/obo/CL_0002027` + +#### Added +- [CD9-positive, CD41-positive megakaryocyte cell](http://purl.obolibrary.org/obo/CL_0002027) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + + +### CD94-negative natural killer cell, mouse `http://purl.obolibrary.org/obo/CL_0002447` +#### Removed +- [CD94-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002447) EquivalentTo [NK1.1-positive natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002438) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [killer cell lectin-like receptor subfamily D member 1](http://purl.obolibrary.org/obo/PR_000001402)) + +- [CD94-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002447) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [killer cell lectin-like receptor subfamily D member 1](http://purl.obolibrary.org/obo/PR_000001402) + +#### Added +- [CD94-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002447) EquivalentTo [NK1.1-positive natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002438) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [killer cell lectin-like receptor subfamily D member 1](http://purl.obolibrary.org/obo/PR_000001402)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090)) + +- [CD94-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002447) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [killer cell lectin-like receptor subfamily D member 1](http://purl.obolibrary.org/obo/PR_000001402) + + +### CD94-negative, Ly49CI-negative natural killer cell, mouse `http://purl.obolibrary.org/obo/CL_0002442` +#### Removed +- [CD94-negative, Ly49CI-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002442) EquivalentTo [natural killer cell](http://purl.obolibrary.org/obo/CL_0000623) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [killer cell lectin-like receptor subfamily D member 1](http://purl.obolibrary.org/obo/PR_000001402)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [killer cell lectin-like receptor 3](http://purl.obolibrary.org/obo/PR_000009618)) + +- [CD94-negative, Ly49CI-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002442) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [killer cell lectin-like receptor subfamily D member 1](http://purl.obolibrary.org/obo/PR_000001402) + +- [CD94-negative, Ly49CI-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002442) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [killer cell lectin-like receptor 3](http://purl.obolibrary.org/obo/PR_000009618) + +#### Added +- [CD94-negative, Ly49CI-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002442) EquivalentTo [natural killer cell](http://purl.obolibrary.org/obo/CL_0000623) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [killer cell lectin-like receptor subfamily D member 1](http://purl.obolibrary.org/obo/PR_000001402)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [killer cell lectin-like receptor 3](http://purl.obolibrary.org/obo/PR_000009618)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090)) + +- [CD94-negative, Ly49CI-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002442) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [killer cell lectin-like receptor 3](http://purl.obolibrary.org/obo/PR_000009618) + +- [CD94-negative, Ly49CI-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002442) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [killer cell lectin-like receptor subfamily D member 1](http://purl.obolibrary.org/obo/PR_000001402) + + +### CHEBI_29985 `http://purl.obolibrary.org/obo/CHEBI_29985` + +#### Added +- Class: [CHEBI_29985](http://purl.obolibrary.org/obo/CHEBI_29985) + + +### CHEBI_57595 `http://purl.obolibrary.org/obo/CHEBI_57595` + +#### Added +- Class: [CHEBI_57595](http://purl.obolibrary.org/obo/CHEBI_57595) + + +### Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell `http://purl.obolibrary.org/obo/CL_0002454` +#### Removed +- [Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0002454) EquivalentTo [CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0002465) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +- [Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0002454) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0002454) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +#### Added +- [Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0002454) EquivalentTo [CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0002465) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +- [Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0002454) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0002454) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + + +### DN1 thymic pro-T cell `http://purl.obolibrary.org/obo/CL_0000894` +#### Removed +- [DN1 thymic pro-T cell](http://purl.obolibrary.org/obo/CL_0000894) EquivalentTo [pro-T cell](http://purl.obolibrary.org/obo/CL_0000827) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [thymus](http://purl.obolibrary.org/obo/UBERON_0002370)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) + +- [DN1 thymic pro-T cell](http://purl.obolibrary.org/obo/CL_0000894) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + +- [DN1 thymic pro-T cell](http://purl.obolibrary.org/obo/CL_0000894) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [DN1 thymic pro-T cell](http://purl.obolibrary.org/obo/CL_0000894) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +#### Added +- [DN1 thymic pro-T cell](http://purl.obolibrary.org/obo/CL_0000894) EquivalentTo [pro-T cell](http://purl.obolibrary.org/obo/CL_0000827) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [thymus](http://purl.obolibrary.org/obo/UBERON_0002370)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) + +- [DN1 thymic pro-T cell](http://purl.obolibrary.org/obo/CL_0000894) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + +- [DN1 thymic pro-T cell](http://purl.obolibrary.org/obo/CL_0000894) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [DN1 thymic pro-T cell](http://purl.obolibrary.org/obo/CL_0000894) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + + +### DN2 thymocyte `http://purl.obolibrary.org/obo/CL_0000806` +#### Removed +- [DN2 thymocyte](http://purl.obolibrary.org/obo/CL_0000806) EquivalentTo [thymocyte](http://purl.obolibrary.org/obo/CL_0000893) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) + +#### Added +- [DN2 thymocyte](http://purl.obolibrary.org/obo/CL_0000806) EquivalentTo [thymocyte](http://purl.obolibrary.org/obo/CL_0000893) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) + + +### DN3 thymocyte `http://purl.obolibrary.org/obo/CL_0000807` +#### Removed +- [DN3 thymocyte](http://purl.obolibrary.org/obo/CL_0000807) EquivalentTo [thymocyte](http://purl.obolibrary.org/obo/CL_0000893) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [pre-T cell receptor complex](http://purl.obolibrary.org/obo/GO_0043384)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) + +- [DN3 thymocyte](http://purl.obolibrary.org/obo/CL_0000807) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307) + +#### Added +- [DN3 thymocyte](http://purl.obolibrary.org/obo/CL_0000807) EquivalentTo [thymocyte](http://purl.obolibrary.org/obo/CL_0000893) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [pre-T cell receptor complex](http://purl.obolibrary.org/obo/GO_0043384)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) + +- [DN3 thymocyte](http://purl.obolibrary.org/obo/CL_0000807) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307) + + +### DN4 thymocyte `http://purl.obolibrary.org/obo/CL_0000808` +#### Removed +- [DN4 thymocyte](http://purl.obolibrary.org/obo/CL_0000808) EquivalentTo [thymocyte](http://purl.obolibrary.org/obo/CL_0000893) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [pre-T cell receptor complex](http://purl.obolibrary.org/obo/GO_0043384)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) + +- [DN4 thymocyte](http://purl.obolibrary.org/obo/CL_0000808) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307) + +- [DN4 thymocyte](http://purl.obolibrary.org/obo/CL_0000808) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + +#### Added +- [DN4 thymocyte](http://purl.obolibrary.org/obo/CL_0000808) EquivalentTo [thymocyte](http://purl.obolibrary.org/obo/CL_0000893) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [pre-T cell receptor complex](http://purl.obolibrary.org/obo/GO_0043384)) + +- [DN4 thymocyte](http://purl.obolibrary.org/obo/CL_0000808) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + +- [DN4 thymocyte](http://purl.obolibrary.org/obo/CL_0000808) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307) + + +### DNA binding `http://purl.obolibrary.org/obo/GO_0003677` +#### Removed +- [DNA binding](http://purl.obolibrary.org/obo/GO_0003677) SubClassOf [nucleic acid binding](http://purl.obolibrary.org/obo/GO_0003676) + +#### Added +- [DNA binding](http://purl.obolibrary.org/obo/GO_0003677) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### DNA biosynthetic process `http://purl.obolibrary.org/obo/GO_0071897` +#### Removed +- [DNA biosynthetic process](http://purl.obolibrary.org/obo/GO_0071897) SubClassOf [nucleobase-containing compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0034654) + +- [DNA biosynthetic process](http://purl.obolibrary.org/obo/GO_0071897) SubClassOf [macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0009059) + +#### Added +- [DNA biosynthetic process](http://purl.obolibrary.org/obo/GO_0071897) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### DNA catabolic process `http://purl.obolibrary.org/obo/GO_0006308` +#### Removed +- [DNA catabolic process](http://purl.obolibrary.org/obo/GO_0006308) SubClassOf [nucleobase-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0034655) + +- [DNA catabolic process](http://purl.obolibrary.org/obo/GO_0006308) SubClassOf [cellular macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0044265) + +#### Added +- [DNA catabolic process](http://purl.obolibrary.org/obo/GO_0006308) SubClassOf [macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0009057) + + +### DNA metabolic process `http://purl.obolibrary.org/obo/GO_0006259` +#### Removed +- [DNA metabolic process](http://purl.obolibrary.org/obo/GO_0006259) SubClassOf [cellular macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0044260) + +- [DNA metabolic process](http://purl.obolibrary.org/obo/GO_0006259) SubClassOf [nucleic acid metabolic process](http://purl.obolibrary.org/obo/GO_0090304) + +#### Added +- [DNA metabolic process](http://purl.obolibrary.org/obo/GO_0006259) SubClassOf [macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0043170) + + +### DNA nuclease activity `http://purl.obolibrary.org/obo/GO_0004536` +#### Removed +- [DNA nuclease activity](http://purl.obolibrary.org/obo/GO_0004536) [label](http://www.w3.org/2000/01/rdf-schema#label) "deoxyribonuclease activity" + +#### Added +- [DNA nuclease activity](http://purl.obolibrary.org/obo/GO_0004536) [label](http://www.w3.org/2000/01/rdf-schema#label) "DNA nuclease activity" + +- [DNA nuclease activity](http://purl.obolibrary.org/obo/GO_0004536) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "deoxyribonuclease activity" + + +### DNA transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0051035` +#### Removed +- [DNA transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051035) SubClassOf [nucleic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051032) + +#### Added +- [DNA transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051035) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + +### DNA transport `http://purl.obolibrary.org/obo/GO_0051027` +#### Removed +- [DNA transport](http://purl.obolibrary.org/obo/GO_0051027) SubClassOf [nucleic acid transport](http://purl.obolibrary.org/obo/GO_0050657) + +#### Added +- [DNA transport](http://purl.obolibrary.org/obo/GO_0051027) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### Daphnia magna metabolite `http://purl.obolibrary.org/obo/CHEBI_83056` +#### Removed +- [Daphnia magna metabolite](http://purl.obolibrary.org/obo/CHEBI_83056) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [Daphnia magna metabolite](http://purl.obolibrary.org/obo/CHEBI_83056) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [Daphnia magna metabolite](http://purl.obolibrary.org/obo/CHEBI_83056) [label](http://www.w3.org/2000/01/rdf-schema#label) "Daphnia magna metabolite" + +- [Daphnia magna metabolite](http://purl.obolibrary.org/obo/CHEBI_83056) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Daphnia magna metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Daphnia magna metabolite](http://purl.obolibrary.org/obo/CHEBI_83056) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:83056" + +- [Daphnia magna metabolite](http://purl.obolibrary.org/obo/CHEBI_83056) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A Daphnia metabolite produced by the species Daphnia magna." + +- Class: [Daphnia magna metabolite](http://purl.obolibrary.org/obo/CHEBI_83056) + +- [Daphnia magna metabolite](http://purl.obolibrary.org/obo/CHEBI_83056) SubClassOf [Daphnia metabolite](http://purl.obolibrary.org/obo/CHEBI_83057) + + + +### Daphnia metabolite `http://purl.obolibrary.org/obo/CHEBI_83057` +#### Removed +- [Daphnia metabolite](http://purl.obolibrary.org/obo/CHEBI_83057) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:83057" + +- [Daphnia metabolite](http://purl.obolibrary.org/obo/CHEBI_83057) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [Daphnia metabolite](http://purl.obolibrary.org/obo/CHEBI_83057) [label](http://www.w3.org/2000/01/rdf-schema#label) "Daphnia metabolite" + +- [Daphnia metabolite](http://purl.obolibrary.org/obo/CHEBI_83057) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Daphnia metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Daphnia metabolite](http://purl.obolibrary.org/obo/CHEBI_83057) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [Daphnia metabolite](http://purl.obolibrary.org/obo/CHEBI_83057) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Daphnia" + +- [Daphnia metabolite](http://purl.obolibrary.org/obo/CHEBI_83057) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia" + +- Class: [Daphnia metabolite](http://purl.obolibrary.org/obo/CHEBI_83057) + +- [Daphnia metabolite](http://purl.obolibrary.org/obo/CHEBI_83057) SubClassOf [crustacean metabolite](http://purl.obolibrary.org/obo/CHEBI_83039) + + + +### Dx5-negative, NK1.1-positive immature natural killer cell, mouse `http://purl.obolibrary.org/obo/CL_0002346` +#### Removed +- [Dx5-negative, NK1.1-positive immature natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002346) EquivalentTo [immature natural killer cell](http://purl.obolibrary.org/obo/CL_0000823) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [killer cell lectin-like receptor subfamily B member 1C](http://purl.obolibrary.org/obo/PR_000002977)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-2](http://purl.obolibrary.org/obo/PR_000001008)) + +- [Dx5-negative, NK1.1-positive immature natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002346) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-2](http://purl.obolibrary.org/obo/PR_000001008) + +#### Added +- [Dx5-negative, NK1.1-positive immature natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002346) EquivalentTo [immature natural killer cell](http://purl.obolibrary.org/obo/CL_0000823) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-2](http://purl.obolibrary.org/obo/PR_000001008)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [killer cell lectin-like receptor subfamily B member 1C](http://purl.obolibrary.org/obo/PR_000002977)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090)) + +- [Dx5-negative, NK1.1-positive immature natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002346) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-2](http://purl.obolibrary.org/obo/PR_000001008) + + +### EC 2.* (transferase) inhibitor `http://purl.obolibrary.org/obo/CHEBI_71300` +#### Removed +- [EC 2.* (transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_71300) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 2.* inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.* (transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_71300) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Transferase" + +- [EC 2.* (transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_71300) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "transferase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.* (transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_71300) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [EC 2.* (transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_71300) [label](http://www.w3.org/2000/01/rdf-schema#label) "EC 2.* (transferase) inhibitor" + +- [EC 2.* (transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_71300) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 2.* (transferase) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.* (transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_71300) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An enzyme inhibitor that inhibits the action of a transferase (EC 2.*)" + +- [EC 2.* (transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_71300) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [EC 2.* (transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_71300) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:71300" + +- [EC 2.* (transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_71300) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 2 inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.* (transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_71300) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 2 inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.* (transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_71300) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "transferase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.* (transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_71300) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 2.* inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [EC 2.* (transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_71300) + +- [EC 2.* (transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_71300) SubClassOf [enzyme inhibitor](http://purl.obolibrary.org/obo/CHEBI_23924) + + + +### EC 2.1.* (C1-transferase) inhibitor `http://purl.obolibrary.org/obo/CHEBI_76655` +#### Removed +- [EC 2.1.* (C1-transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76655) [label](http://www.w3.org/2000/01/rdf-schema#label) "EC 2.1.* (C1-transferase) inhibitor" + +- [EC 2.1.* (C1-transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76655) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "one-carbon-containing group transferase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.* (C1-transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76655) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [EC 2.1.* (C1-transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76655) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 2.1.* inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.* (C1-transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76655) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "one-carbon-containing group transferase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.* (C1-transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76655) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A transferase inhibitor inhibiting the action of transferase of a one-carbon-containing group (EC 2.1.*.*)." + +- [EC 2.1.* (C1-transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76655) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "C1-transferase (EC 2.1.*) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.* (C1-transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76655) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [EC 2.1.* (C1-transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76655) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "C1-transferase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.* (C1-transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76655) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "C1-transferase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.* (C1-transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76655) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 2.1.* (C1-transferase) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.* (C1-transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76655) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:76655" + +- [EC 2.1.* (C1-transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76655) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "C1-transferase (EC 2.1.*) inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.* (C1-transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76655) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 2.1.* inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [EC 2.1.* (C1-transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76655) + +- [EC 2.1.* (C1-transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76655) SubClassOf [EC 2.* (transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_71300) + + + +### EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor `http://purl.obolibrary.org/obo/CHEBI_76874` +#### Removed +- [EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76874) [label](http://www.w3.org/2000/01/rdf-schema#label) "EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor" + +- [EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76874) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76874) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydroxymethyl-, formyl- and related transferases (EC 2.1.2.*) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76874) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 2.1.2.* inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76874) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any hydroxymethyl-, formyl- and related transferase (EC 2.1.2.*)." + +- [EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76874) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydroxymethyl-, formyl- and related transferases (EC 2.1.2.*) inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76874) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 2.1.2.* inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76874) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76874) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76874) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:76874" + +- Class: [EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76874) + +- [EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76874) SubClassOf [EC 2.1.* (C1-transferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76655) + + + +### EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor `http://purl.obolibrary.org/obo/CHEBI_64570` +#### Removed +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glycine hydroxymethyltransferase (EC 2.1.2.1) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "serine aldolase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [label](http://www.w3.org/2000/01/rdf-schema#label) "EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "L-threonine aldolase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "serine aldolase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "serine hydroxymethyltransferase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 2.1.2.1 inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor that interferes with the action of glycine hydroxymethyltransferase (EC 2.1.2.1)." + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "serine hydroxymethylase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "serine transhydroxymethylase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Glycine_hydroxymethyltransferase" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "allothreonine aldolase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "threonine aldolase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glycine hydroxymethyltransferase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "threonine aldolase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glycine hydroxymethyltransferase (EC 2.1.2.1) inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "L-serine hydroxymethyltransferase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "serine hydroxymethylase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 2.1.2.1 inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "L-threonine aldolase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:64570" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glycine hydroxymethyltransferase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "serine hydroxymethyltransferase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "allothreonine aldolase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "L-serine hydroxymethyltransferase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "serine transhydroxymethylase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) + +- [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) SubClassOf [EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76874) + + + +### EC 3.* (hydrolase) inhibitor `http://purl.obolibrary.org/obo/CHEBI_76759` +#### Removed +- [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrolase (EC 3.*) inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrolase (EC 3.*) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hydrolase" + +- [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*)." + +- [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrolase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.*.*.* inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.* inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.* (hydrolase) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:76759" + +- [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) [label](http://www.w3.org/2000/01/rdf-schema#label) "EC 3.* (hydrolase) inhibitor" + +- [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.*.*.* inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.* inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrolase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) + +- [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) SubClassOf [enzyme inhibitor](http://purl.obolibrary.org/obo/CHEBI_23924) + + + +### EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor `http://purl.obolibrary.org/obo/CHEBI_76764` +#### Removed +- [EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76764) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.5.* inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76764) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76764) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76764) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76764) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76764) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76764) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*)." + +- [EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76764) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:76764" + +- [EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76764) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76764) [label](http://www.w3.org/2000/01/rdf-schema#label) "EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor" + +- [EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76764) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76764) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.5.* inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76764) + +- [EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76764) SubClassOf [EC 3.* (hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76759) + + + +### EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor `http://purl.obolibrary.org/obo/CHEBI_76807` +#### Removed +- [EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76807) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76807) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76807) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.5.1.* inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76807) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76807) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:76807" + +- [EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76807) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.5.1.* inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76807) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76807) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*)." + +- [EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76807) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76807) [label](http://www.w3.org/2000/01/rdf-schema#label) "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor" + +- Class: [EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76807) + +- [EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76807) SubClassOf [EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76764) + + + +### EC 3.5.1.4 (amidase) inhibitor `http://purl.obolibrary.org/obo/CHEBI_77941` +#### Removed +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "amidase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "deaminase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "deaminase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acylamide amidohydrolase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fatty acylamidase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Amidase" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "amidase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "N-acetylaminohydrolase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "amidase (EC 3.5.1.4) inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acylamidase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "amidohydrolase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:77941" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4)." + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [label](http://www.w3.org/2000/01/rdf-schema#label) "EC 3.5.1.4 (amidase) inhibitor" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "amidase (EC 3.5.1.4) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.5.1.4 inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "amidohydrolase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.5.1.4 inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fatty acylamidase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.5.1.4 (amidase) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acylamide amidohydrolase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acylamidase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "N-acetylaminohydrolase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) + +- [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) SubClassOf [EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76807) + + + +### EC 3.5.1.98 (histone deacetylase) inhibitor `http://purl.obolibrary.org/obo/CHEBI_61115` +#### Removed +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HDACis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "histone deacetylase (EC 3.5.1.98) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "histone amidohydrolase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "histone deacetylase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "histone deacetylase inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HDI" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:61115" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HDIs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HDAC inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HDACi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98)." + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HDAC inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "histone amidohydrolase inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [label](http://www.w3.org/2000/01/rdf-schema#label) "EC 3.5.1.98 (histone deacetylase) inhibitor" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.5.1.98 inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Histone_deacetylase_inhibitor" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.5.1.98 (histone deacetylase) inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "histone deacetylase (EC 3.5.1.98) inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EC 3.5.1.98 inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) + +- [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) SubClassOf [EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_76807) + + + +### Escherichia coli metabolite `http://purl.obolibrary.org/obo/CHEBI_76971` +#### Removed +- [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) [label](http://www.w3.org/2000/01/rdf-schema#label) "Escherichia coli metabolite" + +- [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "E.coli metabolite" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any bacterial metabolite produced during a metabolic reaction in Escherichia coli." + +- [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:76971" + +- [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "E.coli metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Escherichia coli metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) + +- [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) SubClassOf [bacterial metabolite](http://purl.obolibrary.org/obo/CHEBI_76969) + + + +### F4/80-negative adipose macrophage `http://purl.obolibrary.org/obo/CL_0002478` +#### Removed +- [F4/80-negative adipose macrophage](http://purl.obolibrary.org/obo/CL_0002478) EquivalentTo [adipose macrophage](http://purl.obolibrary.org/obo/CL_0002477) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) + +- [F4/80-negative adipose macrophage](http://purl.obolibrary.org/obo/CL_0002478) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813) + +#### Added +- [F4/80-negative adipose macrophage](http://purl.obolibrary.org/obo/CL_0002478) EquivalentTo [adipose macrophage](http://purl.obolibrary.org/obo/CL_0002477) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) + +- [F4/80-negative adipose macrophage](http://purl.obolibrary.org/obo/CL_0002478) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813) + + +### F4/80-positive adipose macrophage `http://purl.obolibrary.org/obo/CL_0002479` +#### Removed +- [F4/80-positive adipose macrophage](http://purl.obolibrary.org/obo/CL_0002479) EquivalentTo [adipose macrophage](http://purl.obolibrary.org/obo/CL_0002477) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) + +- [F4/80-positive adipose macrophage](http://purl.obolibrary.org/obo/CL_0002479) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613) + +#### Added +- [F4/80-positive adipose macrophage](http://purl.obolibrary.org/obo/CL_0002479) EquivalentTo [adipose macrophage](http://purl.obolibrary.org/obo/CL_0002477) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) + +- [F4/80-positive adipose macrophage](http://purl.obolibrary.org/obo/CL_0002479) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613) + + +### Fc-epsilon RIalpha-high basophil progenitor cell `http://purl.obolibrary.org/obo/CL_0002030` +#### Removed +- [Fc-epsilon RIalpha-high basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0002030) EquivalentTo [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) + +- [Fc-epsilon RIalpha-high basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0002030) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +#### Added +- [Fc-epsilon RIalpha-high basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0002030) EquivalentTo [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431)) + +- [Fc-epsilon RIalpha-high basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0002030) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + + +### Fc-epsilon RIalpha-low mast cell progenitor `http://purl.obolibrary.org/obo/CL_0002029` +#### Removed +- [Fc-epsilon RIalpha-low mast cell progenitor](http://purl.obolibrary.org/obo/CL_0002029) EquivalentTo [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C](http://purl.obolibrary.org/obo/PR_000001006)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin beta-7](http://purl.obolibrary.org/obo/PR_000009143)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) + +#### Added +- [Fc-epsilon RIalpha-low mast cell progenitor](http://purl.obolibrary.org/obo/CL_0002029) EquivalentTo [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C](http://purl.obolibrary.org/obo/PR_000001006)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin beta-7](http://purl.obolibrary.org/obo/PR_000009143)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431)) + + +### GCIs + +#### Added +- [endocrine cell](http://purl.obolibrary.org/obo/CL_0000163) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [stomach](http://purl.obolibrary.org/obo/UBERON_0000945)) SubClassOf [enteroendocrine cell](http://purl.obolibrary.org/obo/CL_0000164) + +- [endocrine cell](http://purl.obolibrary.org/obo/CL_0000163) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [pancreas](http://purl.obolibrary.org/obo/UBERON_0001264)) SubClassOf [enteroendocrine cell](http://purl.obolibrary.org/obo/CL_0000164) + +- [endocrine cell](http://purl.obolibrary.org/obo/CL_0000163) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [intestine](http://purl.obolibrary.org/obo/UBERON_0000160)) SubClassOf [enteroendocrine cell](http://purl.obolibrary.org/obo/CL_0000164) + +- [megakaryocyte](http://purl.obolibrary.org/obo/CL_0000556) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [lung connective tissue](http://purl.obolibrary.org/obo/UBERON_0000114)) SubClassOf [lung megakaryocyte](http://purl.obolibrary.org/obo/CL_4033018) + + +### GlyA-positive basophilic erythroblast `http://purl.obolibrary.org/obo/CL_0002013` +#### Removed +- [GlyA-positive basophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002013) EquivalentTo [basophilic erythroblast](http://purl.obolibrary.org/obo/CL_0000549) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [glycophorin-A](http://purl.obolibrary.org/obo/PR_000001460)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) + +- [GlyA-positive basophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002013) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + +#### Added +- [GlyA-positive basophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002013) EquivalentTo [basophilic erythroblast](http://purl.obolibrary.org/obo/CL_0000549) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [glycophorin-A](http://purl.obolibrary.org/obo/PR_000001460)) + +- [GlyA-positive basophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002013) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + + +### Golgi calcium ion homeostasis `http://purl.obolibrary.org/obo/GO_0032468` + +#### Added +- [Golgi calcium ion homeostasis](http://purl.obolibrary.org/obo/GO_0032468) SubClassOf [calcium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055074) + +- [Golgi calcium ion homeostasis](http://purl.obolibrary.org/obo/GO_0032468) SubClassOf [intracellular chemical homeostasis](http://purl.obolibrary.org/obo/GO_0055082) + + +### Gr1-high classical monocyte `http://purl.obolibrary.org/obo/CL_0002395` +#### Removed +- [Gr1-high classical monocyte](http://purl.obolibrary.org/obo/CL_0002395) EquivalentTo [classical monocyte](http://purl.obolibrary.org/obo/CL_0000860) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrophage colony-stimulating factor 1 receptor](http://purl.obolibrary.org/obo/PR_000002062)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) + +- [Gr1-high classical monocyte](http://purl.obolibrary.org/obo/CL_0002395) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014) + +- [Gr1-high classical monocyte](http://purl.obolibrary.org/obo/CL_0002395) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206) + +- [Gr1-high classical monocyte](http://purl.obolibrary.org/obo/CL_0002395) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879) + +#### Added +- [Gr1-high classical monocyte](http://purl.obolibrary.org/obo/CL_0002395) EquivalentTo [classical monocyte](http://purl.obolibrary.org/obo/CL_0000860) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrophage colony-stimulating factor 1 receptor](http://purl.obolibrary.org/obo/PR_000002062)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980)) + +- [Gr1-high classical monocyte](http://purl.obolibrary.org/obo/CL_0002395) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879) + +- [Gr1-high classical monocyte](http://purl.obolibrary.org/obo/CL_0002395) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014) + +- [Gr1-high classical monocyte](http://purl.obolibrary.org/obo/CL_0002395) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206) + + +### Gr1-high myeloid suppressor cell `http://purl.obolibrary.org/obo/CL_0002467` +#### Removed +- [Gr1-high myeloid suppressor cell](http://purl.obolibrary.org/obo/CL_0002467) EquivalentTo [myeloid suppressor cell](http://purl.obolibrary.org/obo/CL_0000889) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) + +- [Gr1-high myeloid suppressor cell](http://purl.obolibrary.org/obo/CL_0002467) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013) + +#### Added +- [Gr1-high myeloid suppressor cell](http://purl.obolibrary.org/obo/CL_0002467) EquivalentTo [myeloid suppressor cell](http://purl.obolibrary.org/obo/CL_0000889) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980)) + +- [Gr1-high myeloid suppressor cell](http://purl.obolibrary.org/obo/CL_0002467) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013) + + +### Gr1-low non-classical monocyte `http://purl.obolibrary.org/obo/CL_0002058` +#### Removed +- [Gr1-low non-classical monocyte](http://purl.obolibrary.org/obo/CL_0002058) EquivalentTo [non-classical monocyte](http://purl.obolibrary.org/obo/CL_0000875) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrophage colony-stimulating factor 1 receptor](http://purl.obolibrary.org/obo/PR_000002062)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [C-C chemokine receptor type 2](http://purl.obolibrary.org/obo/PR_000001199)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) + +- [Gr1-low non-classical monocyte](http://purl.obolibrary.org/obo/CL_0002058) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014) + +#### Added +- [Gr1-low non-classical monocyte](http://purl.obolibrary.org/obo/CL_0002058) EquivalentTo [non-classical monocyte](http://purl.obolibrary.org/obo/CL_0000875) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrophage colony-stimulating factor 1 receptor](http://purl.obolibrary.org/obo/PR_000002062)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [C-C chemokine receptor type 2](http://purl.obolibrary.org/obo/PR_000001199)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980)) + +- [Gr1-low non-classical monocyte](http://purl.obolibrary.org/obo/CL_0002058) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014) + + +### H1 horizontal cell `http://purl.obolibrary.org/obo/CL_0004217` +#### Removed +- [H1 horizontal cell](http://purl.obolibrary.org/obo/CL_0004217) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/pr#lacks_part) some [axon](http://purl.obolibrary.org/obo/GO_0030424) + +#### Added +- [H1 horizontal cell](http://purl.obolibrary.org/obo/CL_0004217) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [axon](http://purl.obolibrary.org/obo/GO_0030424) + + +### His-Purkinje system cell `http://purl.obolibrary.org/obo/CL_0010007` +#### Removed +- [His-Purkinje system cell](http://purl.obolibrary.org/obo/CL_0010007) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### INN `http://purl.obolibrary.org/obo/chebi#INN` +#### Removed +- AnnotationProperty: [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [INN](http://purl.obolibrary.org/obo/chebi#INN) SubPropertyOf: [synonym_type_property](http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty) + + + +### INN `http://purl.obolibrary.org/obo/fbbt#INN` +#### Removed +- AnnotationProperty: [INN](http://purl.obolibrary.org/obo/fbbt#INN) + +- [INN](http://purl.obolibrary.org/obo/fbbt#INN) SubPropertyOf: [synonym_type_property](http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty) + + + +### IUPAC_NAME `http://purl.obolibrary.org/obo/chebi#IUPAC_NAME` +#### Removed +- AnnotationProperty: [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) SubPropertyOf: [synonym_type_property](http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty) + + + +### IgD-negative CD38-positive IgG memory B cell `http://purl.obolibrary.org/obo/CL_0002107` +#### Removed +- [IgD-negative CD38-positive IgG memory B cell](http://purl.obolibrary.org/obo/CL_0002107) EquivalentTo [CD38-positive IgG memory B cell](http://purl.obolibrary.org/obo/CL_0002105) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) + +#### Added +- [IgD-negative CD38-positive IgG memory B cell](http://purl.obolibrary.org/obo/CL_0002107) EquivalentTo [CD38-positive IgG memory B cell](http://purl.obolibrary.org/obo/CL_0002105) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) + + +### IgD-negative memory B cell `http://purl.obolibrary.org/obo/CL_0001053` +#### Removed +- [IgD-negative memory B cell](http://purl.obolibrary.org/obo/CL_0001053) EquivalentTo [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) + +- [IgD-negative memory B cell](http://purl.obolibrary.org/obo/CL_0001053) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738) + +#### Added +- [IgD-negative memory B cell](http://purl.obolibrary.org/obo/CL_0001053) EquivalentTo [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) + +- [IgD-negative memory B cell](http://purl.obolibrary.org/obo/CL_0001053) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738) + + +### IgG-negative class switched memory B cell `http://purl.obolibrary.org/obo/CL_0002117` +#### Removed +- [IgG-negative class switched memory B cell](http://purl.obolibrary.org/obo/CL_0002117) EquivalentTo [class switched memory B cell](http://purl.obolibrary.org/obo/CL_0000972) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgG immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071735)) + +- [IgG-negative class switched memory B cell](http://purl.obolibrary.org/obo/CL_0002117) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgG immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071735) + +#### Added +- [IgG-negative class switched memory B cell](http://purl.obolibrary.org/obo/CL_0002117) EquivalentTo [class switched memory B cell](http://purl.obolibrary.org/obo/CL_0000972) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgG immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071735)) + +- [IgG-negative class switched memory B cell](http://purl.obolibrary.org/obo/CL_0002117) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgG immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071735) + + +### IgG-negative double negative memory B cell `http://purl.obolibrary.org/obo/CL_0002104` +#### Removed +- [IgG-negative double negative memory B cell](http://purl.obolibrary.org/obo/CL_0002104) EquivalentTo [double negative memory B cell](http://purl.obolibrary.org/obo/CL_0000981) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgG immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071735)) + +- [IgG-negative double negative memory B cell](http://purl.obolibrary.org/obo/CL_0002104) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgG immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071735) + +#### Added +- [IgG-negative double negative memory B cell](http://purl.obolibrary.org/obo/CL_0002104) EquivalentTo [double negative memory B cell](http://purl.obolibrary.org/obo/CL_0000981) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgG immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071735)) + +- [IgG-negative double negative memory B cell](http://purl.obolibrary.org/obo/CL_0002104) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgG immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071735) + + +### IgM memory B cell `http://purl.obolibrary.org/obo/CL_0000971` +#### Removed +- [IgM memory B cell](http://purl.obolibrary.org/obo/CL_0000971) EquivalentTo [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) + +#### Added +- [IgM memory B cell](http://purl.obolibrary.org/obo/CL_0000971) EquivalentTo [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) + + +### Kit and Sca1-positive hematopoietic stem cell `http://purl.obolibrary.org/obo/CL_0001008` +#### Removed +- [Kit and Sca1-positive hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001008) EquivalentTo [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD48 molecule](http://purl.obolibrary.org/obo/PR_000001308)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [natural killer cell receptor 2B4](http://purl.obolibrary.org/obo/PR_000001896)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [killer cell lectin-like receptor subfamily B member 1C](http://purl.obolibrary.org/obo/PR_000002977)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) + +- [Kit and Sca1-positive hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001008) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +- [Kit and Sca1-positive hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001008) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [killer cell lectin-like receptor subfamily B member 1C](http://purl.obolibrary.org/obo/PR_000002977) + +- [Kit and Sca1-positive hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001008) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [natural killer cell receptor 2B4](http://purl.obolibrary.org/obo/PR_000001896) + +- [Kit and Sca1-positive hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001008) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD48 molecule](http://purl.obolibrary.org/obo/PR_000001308) + +- [Kit and Sca1-positive hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001008) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014) + +#### Added +- [Kit and Sca1-positive hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001008) EquivalentTo [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD48 molecule](http://purl.obolibrary.org/obo/PR_000001308)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [natural killer cell receptor 2B4](http://purl.obolibrary.org/obo/PR_000001896)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [killer cell lectin-like receptor subfamily B member 1C](http://purl.obolibrary.org/obo/PR_000002977)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) + +- [Kit and Sca1-positive hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001008) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014) + +- [Kit and Sca1-positive hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001008) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [natural killer cell receptor 2B4](http://purl.obolibrary.org/obo/PR_000001896) + +- [Kit and Sca1-positive hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001008) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [killer cell lectin-like receptor subfamily B member 1C](http://purl.obolibrary.org/obo/PR_000002977) + +- [Kit and Sca1-positive hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001008) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +- [Kit and Sca1-positive hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001008) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD48 molecule](http://purl.obolibrary.org/obo/PR_000001308) + + +### Kit-low proerythroblast `http://purl.obolibrary.org/obo/CL_0002012` +#### Removed +- [Kit-low proerythroblast](http://purl.obolibrary.org/obo/CL_0002012) EquivalentTo [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) + +- [Kit-low proerythroblast](http://purl.obolibrary.org/obo/CL_0002012) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +- [Kit-low proerythroblast](http://purl.obolibrary.org/obo/CL_0002012) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +#### Added +- [Kit-low proerythroblast](http://purl.obolibrary.org/obo/CL_0002012) EquivalentTo [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) + +- [Kit-low proerythroblast](http://purl.obolibrary.org/obo/CL_0002012) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +- [Kit-low proerythroblast](http://purl.obolibrary.org/obo/CL_0002012) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + + +### Kit-low, CD34-positive eosinophil progenitor cell `http://purl.obolibrary.org/obo/CL_0002007` +#### Removed +- [Kit-low, CD34-positive eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0002007) EquivalentTo [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-5 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001867)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) + +- [Kit-low, CD34-positive eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0002007) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +#### Added +- [Kit-low, CD34-positive eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0002007) EquivalentTo [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-5 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001867)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) + +- [Kit-low, CD34-positive eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0002007) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + + +### Kit-negative, Ly-76 high basophilic erythroblast `http://purl.obolibrary.org/obo/CL_0002014` +#### Removed +- [Kit-negative, Ly-76 high basophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002014) EquivalentTo [basophilic erythroblast](http://purl.obolibrary.org/obo/CL_0000549) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) + +- [Kit-negative, Ly-76 high basophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002014) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +- [Kit-negative, Ly-76 high basophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002014) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +- [Kit-negative, Ly-76 high basophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002014) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065) + +#### Added +- [Kit-negative, Ly-76 high basophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002014) EquivalentTo [basophilic erythroblast](http://purl.obolibrary.org/obo/CL_0000549) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) + +- [Kit-negative, Ly-76 high basophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002014) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065) + +- [Kit-negative, Ly-76 high basophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002014) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +- [Kit-negative, Ly-76 high basophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002014) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + + +### Kit-negative, Ly-76 high orthochromatophilic erythroblasts `http://purl.obolibrary.org/obo/CL_0002017` +#### Removed +- [Kit-negative, Ly-76 high orthochromatophilic erythroblasts](http://purl.obolibrary.org/obo/CL_0002017) EquivalentTo [orthochromatic erythroblast](http://purl.obolibrary.org/obo/CL_0000552) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) + +- [Kit-negative, Ly-76 high orthochromatophilic erythroblasts](http://purl.obolibrary.org/obo/CL_0002017) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +- [Kit-negative, Ly-76 high orthochromatophilic erythroblasts](http://purl.obolibrary.org/obo/CL_0002017) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065) + +- [Kit-negative, Ly-76 high orthochromatophilic erythroblasts](http://purl.obolibrary.org/obo/CL_0002017) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +#### Added +- [Kit-negative, Ly-76 high orthochromatophilic erythroblasts](http://purl.obolibrary.org/obo/CL_0002017) EquivalentTo [orthochromatic erythroblast](http://purl.obolibrary.org/obo/CL_0000552) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) + +- [Kit-negative, Ly-76 high orthochromatophilic erythroblasts](http://purl.obolibrary.org/obo/CL_0002017) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +- [Kit-negative, Ly-76 high orthochromatophilic erythroblasts](http://purl.obolibrary.org/obo/CL_0002017) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065) + +- [Kit-negative, Ly-76 high orthochromatophilic erythroblasts](http://purl.obolibrary.org/obo/CL_0002017) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + + +### Kit-negative, Ly-76 high polychromatophilic erythroblast `http://purl.obolibrary.org/obo/CL_0002015` +#### Removed +- [Kit-negative, Ly-76 high polychromatophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002015) EquivalentTo [polychromatophilic erythroblast](http://purl.obolibrary.org/obo/CL_0000550) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) + +- [Kit-negative, Ly-76 high polychromatophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002015) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065) + +- [Kit-negative, Ly-76 high polychromatophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002015) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +- [Kit-negative, Ly-76 high polychromatophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002015) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +#### Added +- [Kit-negative, Ly-76 high polychromatophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002015) EquivalentTo [polychromatophilic erythroblast](http://purl.obolibrary.org/obo/CL_0000550) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) + +- [Kit-negative, Ly-76 high polychromatophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002015) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +- [Kit-negative, Ly-76 high polychromatophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002015) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065) + +- [Kit-negative, Ly-76 high polychromatophilic erythroblast](http://purl.obolibrary.org/obo/CL_0002015) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + + +### Kit-positive erythroid progenitor cell `http://purl.obolibrary.org/obo/CL_0002000` +#### Removed +- [Kit-positive erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002000) EquivalentTo [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [endoglin](http://purl.obolibrary.org/obo/PR_000001345)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [Fc-gamma receptor III complex](http://purl.obolibrary.org/obo/GO_0033001)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-IIb](http://purl.obolibrary.org/obo/PR_000009127)) + +- [Kit-positive erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002000) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865) + +- [Kit-positive erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002000) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-IIb](http://purl.obolibrary.org/obo/PR_000009127) + +- [Kit-positive erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002000) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [Fc-gamma receptor III complex](http://purl.obolibrary.org/obo/GO_0033001) + +- [Kit-positive erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002000) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833) + +- [Kit-positive erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002000) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +- [Kit-positive erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002000) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +#### Added +- [Kit-positive erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002000) EquivalentTo [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [Fc-gamma receptor III complex](http://purl.obolibrary.org/obo/GO_0033001)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-IIb](http://purl.obolibrary.org/obo/PR_000009127)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [endoglin](http://purl.obolibrary.org/obo/PR_000001345)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) + +- [Kit-positive erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002000) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865) + +- [Kit-positive erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002000) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833) + +- [Kit-positive erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002000) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +- [Kit-positive erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002000) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [Fc-gamma receptor III complex](http://purl.obolibrary.org/obo/GO_0033001) + +- [Kit-positive erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002000) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +- [Kit-positive erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002000) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-IIb](http://purl.obolibrary.org/obo/PR_000009127) + + +### Kit-positive granulocyte monocyte progenitor `http://purl.obolibrary.org/obo/CL_0002002` +#### Removed +- [Kit-positive granulocyte monocyte progenitor](http://purl.obolibrary.org/obo/CL_0002002) EquivalentTo [granulocyte monocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000557) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [Fc-gamma receptor III complex](http://purl.obolibrary.org/obo/GO_0033001)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [low affinity immunoglobulin gamma Fc region receptor II](http://purl.obolibrary.org/obo/PR_000001479)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [Thy-1 membrane glycoprotein](http://purl.obolibrary.org/obo/PR_000001843)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) + +- [Kit-positive granulocyte monocyte progenitor](http://purl.obolibrary.org/obo/CL_0002002) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +- [Kit-positive granulocyte monocyte progenitor](http://purl.obolibrary.org/obo/CL_0002002) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [Thy-1 membrane glycoprotein](http://purl.obolibrary.org/obo/PR_000001843) + +- [Kit-positive granulocyte monocyte progenitor](http://purl.obolibrary.org/obo/CL_0002002) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +- [Kit-positive granulocyte monocyte progenitor](http://purl.obolibrary.org/obo/CL_0002002) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206) + +#### Added +- [Kit-positive granulocyte monocyte progenitor](http://purl.obolibrary.org/obo/CL_0002002) EquivalentTo [granulocyte monocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000557) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [Thy-1 membrane glycoprotein](http://purl.obolibrary.org/obo/PR_000001843)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [Fc-gamma receptor III complex](http://purl.obolibrary.org/obo/GO_0033001)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [low affinity immunoglobulin gamma Fc region receptor II](http://purl.obolibrary.org/obo/PR_000001479)) + +- [Kit-positive granulocyte monocyte progenitor](http://purl.obolibrary.org/obo/CL_0002002) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206) + +- [Kit-positive granulocyte monocyte progenitor](http://purl.obolibrary.org/obo/CL_0002002) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +- [Kit-positive granulocyte monocyte progenitor](http://purl.obolibrary.org/obo/CL_0002002) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [Thy-1 membrane glycoprotein](http://purl.obolibrary.org/obo/PR_000001843) + +- [Kit-positive granulocyte monocyte progenitor](http://purl.obolibrary.org/obo/CL_0002002) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + + +### Kit-positive megakaryocyte progenitor cell `http://purl.obolibrary.org/obo/CL_0002024` +#### Removed +- [Kit-positive megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0002024) EquivalentTo [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD9 molecule](http://purl.obolibrary.org/obo/PR_000005178)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [low affinity immunoglobulin gamma Fc region receptor II](http://purl.obolibrary.org/obo/PR_000001479)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) + +- [Kit-positive megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0002024) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +- [Kit-positive megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0002024) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833) + +- [Kit-positive megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0002024) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +#### Added +- [Kit-positive megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0002024) EquivalentTo [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD9 molecule](http://purl.obolibrary.org/obo/PR_000005178)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [low affinity immunoglobulin gamma Fc region receptor II](http://purl.obolibrary.org/obo/PR_000001479)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) + +- [Kit-positive megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0002024) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833) + +- [Kit-positive megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0002024) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +- [Kit-positive megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0002024) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + + +### Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell `http://purl.obolibrary.org/obo/CL_0002006` +#### Removed +- [Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002006) EquivalentTo [megakaryocyte-erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0000050) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [Fc-gamma receptor III complex](http://purl.obolibrary.org/obo/GO_0033001)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor II](http://purl.obolibrary.org/obo/PR_000001479)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [Thy-1 membrane glycoprotein](http://purl.obolibrary.org/obo/PR_000001843)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) + +- [Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002006) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +- [Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002006) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + +- [Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002006) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [Thy-1 membrane glycoprotein](http://purl.obolibrary.org/obo/PR_000001843) + +- [Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002006) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor II](http://purl.obolibrary.org/obo/PR_000001479) + +- [Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002006) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +#### Added +- [Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002006) EquivalentTo [megakaryocyte-erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0000050) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor II](http://purl.obolibrary.org/obo/PR_000001479)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [Thy-1 membrane glycoprotein](http://purl.obolibrary.org/obo/PR_000001843)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [Fc-gamma receptor III complex](http://purl.obolibrary.org/obo/GO_0033001)) + +- [Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002006) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor II](http://purl.obolibrary.org/obo/PR_000001479) + +- [Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002006) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +- [Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002006) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + +- [Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002006) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [Thy-1 membrane glycoprotein](http://purl.obolibrary.org/obo/PR_000001843) + +- [Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0002006) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + + +### Kit-positive, CD34-positive common myeloid progenitor `http://purl.obolibrary.org/obo/CL_0001023` +#### Removed +- [Kit-positive, CD34-positive common myeloid progenitor](http://purl.obolibrary.org/obo/CL_0001023) EquivalentTo [common myeloid progenitor, CD34-positive](http://purl.obolibrary.org/obo/CL_0001059) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [Fc-gamma receptor III complex](http://purl.obolibrary.org/obo/GO_0033001)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [low affinity immunoglobulin gamma Fc region receptor II-b](http://purl.obolibrary.org/obo/PR_000001481)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) + +- [Kit-positive, CD34-positive common myeloid progenitor](http://purl.obolibrary.org/obo/CL_0001023) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +- [Kit-positive, CD34-positive common myeloid progenitor](http://purl.obolibrary.org/obo/CL_0001023) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +#### Added +- [Kit-positive, CD34-positive common myeloid progenitor](http://purl.obolibrary.org/obo/CL_0001023) EquivalentTo [common myeloid progenitor, CD34-positive](http://purl.obolibrary.org/obo/CL_0001059) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [Fc-gamma receptor III complex](http://purl.obolibrary.org/obo/GO_0033001)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [low affinity immunoglobulin gamma Fc region receptor II-b](http://purl.obolibrary.org/obo/PR_000001481)) + +- [Kit-positive, CD34-positive common myeloid progenitor](http://purl.obolibrary.org/obo/CL_0001023) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +- [Kit-positive, CD34-positive common myeloid progenitor](http://purl.obolibrary.org/obo/CL_0001023) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + + +### Kit-positive, Sca1-positive common lymphoid progenitor `http://purl.obolibrary.org/obo/CL_0001025` +#### Removed +- [Kit-positive, Sca1-positive common lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0001025) EquivalentTo [common lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0000051) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) + +- [Kit-positive, Sca1-positive common lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0001025) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014) + +#### Added +- [Kit-positive, Sca1-positive common lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0001025) EquivalentTo [common lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0000051) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) + +- [Kit-positive, Sca1-positive common lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0001025) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014) + + +### Kit-positive, integrin beta7-high basophil mast progenitor cell `http://purl.obolibrary.org/obo/CL_0002044` +#### Removed +- [Kit-positive, integrin beta7-high basophil mast progenitor cell](http://purl.obolibrary.org/obo/CL_0002044) EquivalentTo [basophil mast progenitor cell](http://purl.obolibrary.org/obo/CL_0002028) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [low affinity immunoglobulin gamma Fc region receptor II](http://purl.obolibrary.org/obo/PR_000001479)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [integrin beta-7](http://purl.obolibrary.org/obo/PR_000009143)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) + +- [Kit-positive, integrin beta7-high basophil mast progenitor cell](http://purl.obolibrary.org/obo/CL_0002044) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065) + +- [Kit-positive, integrin beta7-high basophil mast progenitor cell](http://purl.obolibrary.org/obo/CL_0002044) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +#### Added +- [Kit-positive, integrin beta7-high basophil mast progenitor cell](http://purl.obolibrary.org/obo/CL_0002044) EquivalentTo [basophil mast progenitor cell](http://purl.obolibrary.org/obo/CL_0002028) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [low affinity immunoglobulin gamma Fc region receptor II](http://purl.obolibrary.org/obo/PR_000001479)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [integrin beta-7](http://purl.obolibrary.org/obo/PR_000009143)) + +- [Kit-positive, integrin beta7-high basophil mast progenitor cell](http://purl.obolibrary.org/obo/CL_0002044) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +- [Kit-positive, integrin beta7-high basophil mast progenitor cell](http://purl.obolibrary.org/obo/CL_0002044) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065) + + +### L cone cell `http://purl.obolibrary.org/obo/CL_0003048` + +#### Added +- [L cone cell](http://purl.obolibrary.org/obo/CL_0003048) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "long wavelength sensitive cone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:31117170" + +- [L cone cell](http://purl.obolibrary.org/obo/CL_0003048) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "L-cone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:29603924" + +- [L cone cell](http://purl.obolibrary.org/obo/CL_0003048) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "L cone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32555229" + +- [L cone cell](http://purl.obolibrary.org/obo/CL_0003048) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "long-wavelength cone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://doi.org/10.1038/323623a0" + +- [L cone cell](http://purl.obolibrary.org/obo/CL_0003048) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "long- (L) wavelength-sensitive cone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://doi.org/10.7554/eLife.39166" + + +### L-alpha-amino acid `http://purl.obolibrary.org/obo/CHEBI_15705` +#### Removed +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "L-alpha-amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00151" + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [label](http://www.w3.org/2000/01/rdf-schema#label) "L-alpha-amino acid" + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:21224" + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "L-alpha-amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2H4NO2R" + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "L-alpha-amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:15705" + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:6175" + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13072" + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13797" + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any alpha-amino acid having L-configuration at the alpha-carbon." + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "L-2-Amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "74.02420" + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "N[C@@H]([*])C(O)=O" + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13243" + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [mass](http://purl.obolibrary.org/obo/chebi/mass) "74.05870" + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "L-Amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- Class: [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [L-alpha-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_59814) + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) SubClassOf [is_tautomer_of](http://purl.obolibrary.org/obo/chebi#is_tautomer_of) some [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) + +- [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) SubClassOf [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) + + + +### L-alpha-amino acid anion `http://purl.obolibrary.org/obo/CHEBI_59814` +#### Removed +- [L-alpha-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_59814) [label](http://www.w3.org/2000/01/rdf-schema#label) "L-alpha-amino acid anion" + +- [L-alpha-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_59814) [mass](http://purl.obolibrary.org/obo/chebi/mass) "73.051" + +- [L-alpha-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_59814) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "73.01638" + +- [L-alpha-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_59814) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[C@H](C(=O)[O-])(N)*" + +- [L-alpha-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_59814) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:59814" + +- [L-alpha-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_59814) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "L-alpha-amino carboxylate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [L-alpha-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_59814) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [L-alpha-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_59814) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [L-alpha-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_59814) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [L-alpha-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_59814) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Conjugate base of an L-alpha-amino acid arising from deprotonation of the C-1 carboxy group." + +- [L-alpha-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_59814) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2H3NO2R" + +- Class: [L-alpha-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_59814) + +- [L-alpha-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_59814) SubClassOf [alpha-amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_33558) + +- [L-alpha-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_59814) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) + + + +### L-alpha-amino acid transmembrane transport `http://purl.obolibrary.org/obo/GO_1902475` +#### Removed +- [L-alpha-amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902475) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2013-10-25T15:17:39Z" + +- [L-alpha-amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902475) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902475" + +- [L-alpha-amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902475) [label](http://www.w3.org/2000/01/rdf-schema#label) "L-alpha-amino acid transmembrane transport" + +- [L-alpha-amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902475) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of L-alpha-amino acid across a membrane." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:14668347" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:kmv" + +- [L-alpha-amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902475) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [L-alpha-amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902475) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "kmv" + +- Class: [L-alpha-amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902475) + +- [L-alpha-amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902475) EquivalentTo [transmembrane transport](http://purl.obolibrary.org/obo/GO_0055085) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869)) + +- [L-alpha-amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902475) SubClassOf [transmembrane transport](http://purl.obolibrary.org/obo/GO_0055085) + +- [L-alpha-amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902475) SubClassOf [L-amino acid transport](http://purl.obolibrary.org/obo/GO_0015807) + + + +### L-alpha-amino acid zwitterion `http://purl.obolibrary.org/obo/CHEBI_59869` +#### Removed +- [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "74.02420" + +- [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:59869" + +- [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[NH3+][C@@H]([*])C([O-])=O" + +- [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) [label](http://www.w3.org/2000/01/rdf-schema#label) "L-alpha-amino acid zwitterion" + +- [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) [mass](http://purl.obolibrary.org/obo/chebi/mass) "74.059" + +- [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Zwitterionic form of an L-alpha-amino acid having an anionic carboxy group and a protonated amino group." + +- [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2H4NO2R" + +- [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "L-alpha-amino acid zwitterions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "an L-alpha-amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) + +- [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) SubClassOf [alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_78608) + +- [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) SubClassOf [is_tautomer_of](http://purl.obolibrary.org/obo/chebi#is_tautomer_of) some [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) + + + +### L-amino acid transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015179` +#### Removed +- [L-amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015179) [label](http://www.w3.org/2000/01/rdf-schema#label) "L-amino acid transmembrane transporter activity" + +- [L-amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015179) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "L-amino acid transporter activity" + +- [L-amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015179) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0815340729" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_transport" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jsg" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [L-amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015179) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [L-amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015179) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015179" + +- [L-amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015179) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-212614" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "Glutamine transport from astrocytes" + +- Class: [L-amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015179) + +- [L-amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015179) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869)) + +- [L-amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015179) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [L-alpha-amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902475) + - [source](http://www.geneontology.org/formats/oboInOwl#http://purl.org/dc/terms/source) "GO_REF:0000090" + +- [L-amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015179) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) + +- [L-amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015179) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + + +### L-amino acid transport `http://purl.obolibrary.org/obo/GO_0015807` +#### Removed +- [L-amino acid transport](http://purl.obolibrary.org/obo/GO_0015807) [label](http://www.w3.org/2000/01/rdf-schema#label) "L-amino acid transport" + +- [L-amino acid transport](http://purl.obolibrary.org/obo/GO_0015807) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [L-amino acid transport](http://purl.obolibrary.org/obo/GO_0015807) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jsg" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [L-amino acid transport](http://purl.obolibrary.org/obo/GO_0015807) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015807" + +- Class: [L-amino acid transport](http://purl.obolibrary.org/obo/GO_0015807) + +- [L-amino acid transport](http://purl.obolibrary.org/obo/GO_0015807) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869)) + +- [L-amino acid transport](http://purl.obolibrary.org/obo/GO_0015807) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [L-alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59869) + +- [L-amino acid transport](http://purl.obolibrary.org/obo/GO_0015807) SubClassOf [organic substance transport](http://purl.obolibrary.org/obo/GO_0071702) + + + +### L-glutamate biosynthetic process `http://purl.obolibrary.org/obo/GO_0097054` + +#### Added +- [L-glutamate biosynthetic process](http://purl.obolibrary.org/obo/GO_0097054) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "L-glutamate synthesis" + +- [L-glutamate biosynthetic process](http://purl.obolibrary.org/obo/GO_0097054) [label](http://www.w3.org/2000/01/rdf-schema#label) "L-glutamate biosynthetic process" + +- [L-glutamate biosynthetic process](http://purl.obolibrary.org/obo/GO_0097054) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "L-glutamate anabolism" + +- [L-glutamate biosynthetic process](http://purl.obolibrary.org/obo/GO_0097054) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0097054" + +- [L-glutamate biosynthetic process](http://purl.obolibrary.org/obo/GO_0097054) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "pr" + +- [L-glutamate biosynthetic process](http://purl.obolibrary.org/obo/GO_0097054) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-05-24T04:30:38Z" + +- [L-glutamate biosynthetic process](http://purl.obolibrary.org/obo/GO_0097054) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [L-glutamate biosynthetic process](http://purl.obolibrary.org/obo/GO_0097054) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "L-glutamate biosynthesis" + +- [L-glutamate biosynthetic process](http://purl.obolibrary.org/obo/GO_0097054) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "L-glutamate formation" + +- [L-glutamate biosynthetic process](http://purl.obolibrary.org/obo/GO_0097054) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:yaf" + +- Class: [L-glutamate biosynthetic process](http://purl.obolibrary.org/obo/GO_0097054) + +- [L-glutamate biosynthetic process](http://purl.obolibrary.org/obo/GO_0097054) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [CHEBI_29985](http://purl.obolibrary.org/obo/CHEBI_29985)) + +- [L-glutamate biosynthetic process](http://purl.obolibrary.org/obo/GO_0097054) SubClassOf [glutamate biosynthetic process](http://purl.obolibrary.org/obo/GO_0006537) + +- [L-glutamate biosynthetic process](http://purl.obolibrary.org/obo/GO_0097054) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [CHEBI_29985](http://purl.obolibrary.org/obo/CHEBI_29985) + + +### L-glutamate import `http://purl.obolibrary.org/obo/GO_0051938` + +#### Added +- [L-glutamate import](http://purl.obolibrary.org/obo/GO_0051938) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jsg" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [L-glutamate import](http://purl.obolibrary.org/obo/GO_0051938) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [L-glutamate import](http://purl.obolibrary.org/obo/GO_0051938) [label](http://www.w3.org/2000/01/rdf-schema#label) "L-glutamate import" + +- [L-glutamate import](http://purl.obolibrary.org/obo/GO_0051938) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0051938" + +- [L-glutamate import](http://purl.obolibrary.org/obo/GO_0051938) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "L-glutamate uptake" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- Class: [L-glutamate import](http://purl.obolibrary.org/obo/GO_0051938) + +- [L-glutamate import](http://purl.obolibrary.org/obo/GO_0051938) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_29985](http://purl.obolibrary.org/obo/CHEBI_29985)) + +- [L-glutamate import](http://purl.obolibrary.org/obo/GO_0051938) SubClassOf [acidic amino acid transport](http://purl.obolibrary.org/obo/GO_0015800) + +- [L-glutamate import](http://purl.obolibrary.org/obo/GO_0051938) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_29985](http://purl.obolibrary.org/obo/CHEBI_29985) + + +### L-glutamate transmembrane transport `http://purl.obolibrary.org/obo/GO_0015813` + +#### Added +- [L-glutamate transmembrane transport](http://purl.obolibrary.org/obo/GO_0015813) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of L-glutamate across a membrane." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21307582" + +- [L-glutamate transmembrane transport](http://purl.obolibrary.org/obo/GO_0015813) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015813" + +- [L-glutamate transmembrane transport](http://purl.obolibrary.org/obo/GO_0015813) [label](http://www.w3.org/2000/01/rdf-schema#label) "L-glutamate transmembrane transport" + +- [L-glutamate transmembrane transport](http://purl.obolibrary.org/obo/GO_0015813) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mitochondrial aspartate/glutamate transport" + +- [L-glutamate transmembrane transport](http://purl.obolibrary.org/obo/GO_0015813) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0089711" + +- [L-glutamate transmembrane transport](http://purl.obolibrary.org/obo/GO_0015813) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "L-glutamate transport" + +- [L-glutamate transmembrane transport](http://purl.obolibrary.org/obo/GO_0015813) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [L-glutamate transmembrane transport](http://purl.obolibrary.org/obo/GO_0015813) + +- [L-glutamate transmembrane transport](http://purl.obolibrary.org/obo/GO_0015813) EquivalentTo [acidic amino acid transport](http://purl.obolibrary.org/obo/GO_0015800) and ([results in transport across](http://purl.obolibrary.org/obo/RO_0002342) some [membrane](http://purl.obolibrary.org/obo/GO_0016020)) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_29985](http://purl.obolibrary.org/obo/CHEBI_29985)) + +- [L-glutamate transmembrane transport](http://purl.obolibrary.org/obo/GO_0015813) SubClassOf [amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_0003333) + +- [L-glutamate transmembrane transport](http://purl.obolibrary.org/obo/GO_0015813) SubClassOf [L-glutamate import](http://purl.obolibrary.org/obo/GO_0051938) + + +### L-glutamate transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0005313` + +#### Added +- [L-glutamate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005313) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-5624256" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "Defective SLC17A8 does not exchange cytosolic L-Glu for synaptic vesicle H+" + +- [L-glutamate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005313) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-210444" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "L-Glutamate loading of synaptic vesicle" + +- [L-glutamate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005313) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "glutamate/aspartate:sodium symporter activity" + +- [L-glutamate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005313) [label](http://www.w3.org/2000/01/rdf-schema#label) "L-glutamate transmembrane transporter activity" + +- [L-glutamate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005313) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "L-glutamate transporter activity" + +- [L-glutamate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005313) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "glutamate transmembrane transporter activity" + +- [L-glutamate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005313) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "RHEA:66336" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "skos:broadMatch" + +- [L-glutamate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005313) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0005313" + +- [L-glutamate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005313) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0815340729" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_transport" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [L-glutamate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005313) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-428052" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+" + +- [L-glutamate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005313) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "glutamate/aspartate porter activity" + +- [L-glutamate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005313) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- Class: [L-glutamate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005313) + +- [L-glutamate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005313) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_29985](http://purl.obolibrary.org/obo/CHEBI_29985)) + +- [L-glutamate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005313) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [L-glutamate transmembrane transport](http://purl.obolibrary.org/obo/GO_0015813) + +- [L-glutamate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005313) SubClassOf [acidic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015172) + +- [L-glutamate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005313) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_29985](http://purl.obolibrary.org/obo/CHEBI_29985) + + +### L-histidine transmembrane transport `http://purl.obolibrary.org/obo/GO_0089709` + +#### Added +- [L-histidine transmembrane transport](http://purl.obolibrary.org/obo/GO_0089709) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [L-histidine transmembrane transport](http://purl.obolibrary.org/obo/GO_0089709) [label](http://www.w3.org/2000/01/rdf-schema#label) "L-histidine transmembrane transport" + +- [L-histidine transmembrane transport](http://purl.obolibrary.org/obo/GO_0089709) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0089709" + +- [L-histidine transmembrane transport](http://purl.obolibrary.org/obo/GO_0089709) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of L-histidine across a membrane." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21307582" + +- Class: [L-histidine transmembrane transport](http://purl.obolibrary.org/obo/GO_0089709) + +- [L-histidine transmembrane transport](http://purl.obolibrary.org/obo/GO_0089709) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([results in transport across](http://purl.obolibrary.org/obo/RO_0002342) some [membrane](http://purl.obolibrary.org/obo/GO_0016020)) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_57595](http://purl.obolibrary.org/obo/CHEBI_57595)) + +- [L-histidine transmembrane transport](http://purl.obolibrary.org/obo/GO_0089709) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_57595](http://purl.obolibrary.org/obo/CHEBI_57595) + +- [L-histidine transmembrane transport](http://purl.obolibrary.org/obo/GO_0089709) SubClassOf [transmembrane transport](http://purl.obolibrary.org/obo/GO_0055085) + + +### L-histidine transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0005290` + +#### Added +- [L-histidine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005290) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0005290" + +- [L-histidine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005290) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [L-histidine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005290) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0815340729" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_transport" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [L-histidine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005290) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "histidine/arginine/lysine/ornithine porter activity" + +- [L-histidine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005290) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "L-histidine transporter activity" + +- [L-histidine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005290) [label](http://www.w3.org/2000/01/rdf-schema#label) "L-histidine transmembrane transporter activity" + +- Class: [L-histidine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005290) + +- [L-histidine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005290) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_57595](http://purl.obolibrary.org/obo/CHEBI_57595)) + +- [L-histidine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005290) SubClassOf [basic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015174) + +- [L-histidine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005290) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [L-histidine transmembrane transport](http://purl.obolibrary.org/obo/GO_0089709) + +- [L-histidine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005290) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_57595](http://purl.obolibrary.org/obo/CHEBI_57595) + + +### L-histidine transport `http://purl.obolibrary.org/obo/GO_1902024` + +#### Added +- [L-histidine transport](http://purl.obolibrary.org/obo/GO_1902024) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [L-histidine transport](http://purl.obolibrary.org/obo/GO_1902024) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2013-03-27T16:09:15Z" + +- [L-histidine transport](http://purl.obolibrary.org/obo/GO_1902024) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902024" + +- [L-histidine transport](http://purl.obolibrary.org/obo/GO_1902024) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of a L-histidine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22822152" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:kmv" + +- [L-histidine transport](http://purl.obolibrary.org/obo/GO_1902024) [label](http://www.w3.org/2000/01/rdf-schema#label) "L-histidine transport" + +- [L-histidine transport](http://purl.obolibrary.org/obo/GO_1902024) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "kmv" + +- Class: [L-histidine transport](http://purl.obolibrary.org/obo/GO_1902024) + +- [L-histidine transport](http://purl.obolibrary.org/obo/GO_1902024) EquivalentTo [basic amino acid transport](http://purl.obolibrary.org/obo/GO_0015802) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_57595](http://purl.obolibrary.org/obo/CHEBI_57595)) + +- [L-histidine transport](http://purl.obolibrary.org/obo/GO_1902024) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_57595](http://purl.obolibrary.org/obo/CHEBI_57595) + +- [L-histidine transport](http://purl.obolibrary.org/obo/GO_1902024) SubClassOf [basic amino acid transport](http://purl.obolibrary.org/obo/GO_0015802) + + +### Lewis base `http://purl.obolibrary.org/obo/CHEBI_39144` +#### Removed +- [Lewis base](http://purl.obolibrary.org/obo/CHEBI_39144) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "base de Lewis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [Lewis base](http://purl.obolibrary.org/obo/CHEBI_39144) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "donneur d'une paire d'electrons" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Lewis base](http://purl.obolibrary.org/obo/CHEBI_39144) [label](http://www.w3.org/2000/01/rdf-schema#label) "Lewis base" + +- [Lewis base](http://purl.obolibrary.org/obo/CHEBI_39144) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Lewis-Base" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Lewis base](http://purl.obolibrary.org/obo/CHEBI_39144) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct." + +- [Lewis base](http://purl.obolibrary.org/obo/CHEBI_39144) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [Lewis base](http://purl.obolibrary.org/obo/CHEBI_39144) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:39144" + +- [Lewis base](http://purl.obolibrary.org/obo/CHEBI_39144) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "electron donor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Lewis base](http://purl.obolibrary.org/obo/CHEBI_39144) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Lewis base" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [Lewis base](http://purl.obolibrary.org/obo/CHEBI_39144) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [Lewis base](http://purl.obolibrary.org/obo/CHEBI_39144) + +- [Lewis base](http://purl.obolibrary.org/obo/CHEBI_39144) SubClassOf [donor](http://purl.obolibrary.org/obo/CHEBI_17891) + +- [Lewis base](http://purl.obolibrary.org/obo/CHEBI_39144) SubClassOf [base](http://purl.obolibrary.org/obo/CHEBI_22695) + + + +### Ly49CI-negative natural killer cell, mouse `http://purl.obolibrary.org/obo/CL_0002446` +#### Removed +- [Ly49CI-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002446) EquivalentTo [NK1.1-positive natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002438) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [killer cell lectin-like receptor 3](http://purl.obolibrary.org/obo/PR_000009618)) + +- [Ly49CI-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002446) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [killer cell lectin-like receptor 3](http://purl.obolibrary.org/obo/PR_000009618) + +#### Added +- [Ly49CI-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002446) EquivalentTo [NK1.1-positive natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002438) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [killer cell lectin-like receptor 3](http://purl.obolibrary.org/obo/PR_000009618)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090)) + +- [Ly49CI-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002446) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [killer cell lectin-like receptor 3](http://purl.obolibrary.org/obo/PR_000009618) + + +### Ly49D-negative natural killer cell, mouse `http://purl.obolibrary.org/obo/CL_0002445` +#### Removed +- [Ly49D-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002445) EquivalentTo [NK1.1-positive natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002438) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [killer cell lectin-like receptor 4](http://purl.obolibrary.org/obo/PR_000009619)) + +- [Ly49D-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002445) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [killer cell lectin-like receptor 4](http://purl.obolibrary.org/obo/PR_000009619) + +#### Added +- [Ly49D-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002445) EquivalentTo [NK1.1-positive natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002438) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [killer cell lectin-like receptor 4](http://purl.obolibrary.org/obo/PR_000009619)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090)) + +- [Ly49D-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002445) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [killer cell lectin-like receptor 4](http://purl.obolibrary.org/obo/PR_000009619) + + +### Ly49H-negative natural killer cell, mouse `http://purl.obolibrary.org/obo/CL_0002448` +#### Removed +- [Ly49H-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002448) EquivalentTo [NK1.1-positive natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002438) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [killer cell lectin-like receptor 8](http://purl.obolibrary.org/obo/PR_000009623)) + +- [Ly49H-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002448) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [killer cell lectin-like receptor 8](http://purl.obolibrary.org/obo/PR_000009623) + +#### Added +- [Ly49H-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002448) EquivalentTo [NK1.1-positive natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002438) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [killer cell lectin-like receptor 8](http://purl.obolibrary.org/obo/PR_000009623)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090)) + +- [Ly49H-negative natural killer cell, mouse](http://purl.obolibrary.org/obo/CL_0002448) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [killer cell lectin-like receptor 8](http://purl.obolibrary.org/obo/PR_000009623) + + +### M cone cell `http://purl.obolibrary.org/obo/CL_0003049` + +#### Added +- [M cone cell](http://purl.obolibrary.org/obo/CL_0003049) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "middle-wavelength-sensitive (M) cone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://opg.optica.org/josaa/abstract.cfm?URI=josaa-6-1-153" + +- [M cone cell](http://purl.obolibrary.org/obo/CL_0003049) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "middle- (M) wavelength-sensitive cone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://doi.org/10.7554/eLife.39166" + +- [M cone cell](http://purl.obolibrary.org/obo/CL_0003049) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "middle wavelength sensitive cone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:31117170" + +- [M cone cell](http://purl.obolibrary.org/obo/CL_0003049) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "M-cone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:29603924" + +- [M cone cell](http://purl.obolibrary.org/obo/CL_0003049) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "M cone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32555229" + + +### MHC-II-negative classical monocyte `http://purl.obolibrary.org/obo/CL_0002469` +#### Removed +- [MHC-II-negative classical monocyte](http://purl.obolibrary.org/obo/CL_0002469) EquivalentTo [Gr1-high classical monocyte](http://purl.obolibrary.org/obo/CL_0002395) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) + +- [MHC-II-negative classical monocyte](http://purl.obolibrary.org/obo/CL_0002469) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613) + +#### Added +- [MHC-II-negative classical monocyte](http://purl.obolibrary.org/obo/CL_0002469) EquivalentTo [Gr1-high classical monocyte](http://purl.obolibrary.org/obo/CL_0002395) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) + +- [MHC-II-negative classical monocyte](http://purl.obolibrary.org/obo/CL_0002469) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613) + + +### MHC-II-negative non-classical monocyte `http://purl.obolibrary.org/obo/CL_0002471` +#### Removed +- [MHC-II-negative non-classical monocyte](http://purl.obolibrary.org/obo/CL_0002471) EquivalentTo [Gr1-low non-classical monocyte](http://purl.obolibrary.org/obo/CL_0002058) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) + +- [MHC-II-negative non-classical monocyte](http://purl.obolibrary.org/obo/CL_0002471) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613) + +#### Added +- [MHC-II-negative non-classical monocyte](http://purl.obolibrary.org/obo/CL_0002471) EquivalentTo [Gr1-low non-classical monocyte](http://purl.obolibrary.org/obo/CL_0002058) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) + +- [MHC-II-negative non-classical monocyte](http://purl.obolibrary.org/obo/CL_0002471) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613) + + +### Mycoplasma genitalium metabolite `http://purl.obolibrary.org/obo/CHEBI_131604` +#### Removed +- [Mycoplasma genitalium metabolite](http://purl.obolibrary.org/obo/CHEBI_131604) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [Mycoplasma genitalium metabolite](http://purl.obolibrary.org/obo/CHEBI_131604) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:131604" + +- [Mycoplasma genitalium metabolite](http://purl.obolibrary.org/obo/CHEBI_131604) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Mycoplasma genitalium metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Mycoplasma genitalium metabolite](http://purl.obolibrary.org/obo/CHEBI_131604) [label](http://www.w3.org/2000/01/rdf-schema#label) "Mycoplasma genitalium metabolite" + +- [Mycoplasma genitalium metabolite](http://purl.obolibrary.org/obo/CHEBI_131604) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [Mycoplasma genitalium metabolite](http://purl.obolibrary.org/obo/CHEBI_131604) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium." + +- Class: [Mycoplasma genitalium metabolite](http://purl.obolibrary.org/obo/CHEBI_131604) + +- [Mycoplasma genitalium metabolite](http://purl.obolibrary.org/obo/CHEBI_131604) SubClassOf [bacterial metabolite](http://purl.obolibrary.org/obo/CHEBI_76969) + + + +### NKp44-negative group 3 innate lymphoid cell, human `http://purl.obolibrary.org/obo/CL_0001080` +#### Removed +- [NKp44-negative group 3 innate lymphoid cell, human](http://purl.obolibrary.org/obo/CL_0001080) EquivalentTo [group 3 innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001071) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha (human)](http://purl.obolibrary.org/obo/PR_P16871)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [natural cytotoxicity triggering receptor 2 (human)](http://purl.obolibrary.org/obo/PR_O95944)) + +- [NKp44-negative group 3 innate lymphoid cell, human](http://purl.obolibrary.org/obo/CL_0001080) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [natural cytotoxicity triggering receptor 2 (human)](http://purl.obolibrary.org/obo/PR_O95944) + +#### Added +- [NKp44-negative group 3 innate lymphoid cell, human](http://purl.obolibrary.org/obo/CL_0001080) EquivalentTo [group 3 innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001071) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [natural cytotoxicity triggering receptor 2 (human)](http://purl.obolibrary.org/obo/PR_O95944)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha (human)](http://purl.obolibrary.org/obo/PR_P16871)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) + +- [NKp44-negative group 3 innate lymphoid cell, human](http://purl.obolibrary.org/obo/CL_0001080) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [natural cytotoxicity triggering receptor 2 (human)](http://purl.obolibrary.org/obo/PR_O95944) + + +### NMDA receptor agonist `http://purl.obolibrary.org/obo/CHEBI_64571` +#### Removed +- [NMDA receptor agonist](http://purl.obolibrary.org/obo/CHEBI_64571) [label](http://www.w3.org/2000/01/rdf-schema#label) "NMDA receptor agonist" + +- [NMDA receptor agonist](http://purl.obolibrary.org/obo/CHEBI_64571) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [NMDA receptor agonist](http://purl.obolibrary.org/obo/CHEBI_64571) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An excitatory amino acid agonist which binds to NMDA receptors and triggers a response." + +- [NMDA receptor agonist](http://purl.obolibrary.org/obo/CHEBI_64571) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:64571" + +- [NMDA receptor agonist](http://purl.obolibrary.org/obo/CHEBI_64571) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NMDA receptor agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [NMDA receptor agonist](http://purl.obolibrary.org/obo/CHEBI_64571) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "N-methyl-D-aspartate receptor agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [NMDA receptor agonist](http://purl.obolibrary.org/obo/CHEBI_64571) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NMDAR agonist" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [NMDA receptor agonist](http://purl.obolibrary.org/obo/CHEBI_64571) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NMDAR agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [NMDA receptor agonist](http://purl.obolibrary.org/obo/CHEBI_64571) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [NMDA receptor agonist](http://purl.obolibrary.org/obo/CHEBI_64571) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "N-methyl-D-aspartate receptor agonist" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [NMDA receptor agonist](http://purl.obolibrary.org/obo/CHEBI_64571) + +- [NMDA receptor agonist](http://purl.obolibrary.org/obo/CHEBI_64571) SubClassOf [excitatory amino acid agonist](http://purl.obolibrary.org/obo/CHEBI_50103) + + + +### Peyer's patch B cell `http://purl.obolibrary.org/obo/CL_0002402` +#### Removed +- [Peyer's patch B cell](http://purl.obolibrary.org/obo/CL_0002402) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [Peyer's patch](http://purl.obolibrary.org/obo/UBERON_0001211)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) + +- [Peyer's patch B cell](http://purl.obolibrary.org/obo/CL_0002402) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037) + +- [Peyer's patch B cell](http://purl.obolibrary.org/obo/CL_0002402) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +#### Added +- [Peyer's patch B cell](http://purl.obolibrary.org/obo/CL_0002402) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [Peyer's patch](http://purl.obolibrary.org/obo/UBERON_0001211)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338)) + +- [Peyer's patch B cell](http://purl.obolibrary.org/obo/CL_0002402) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037) + +- [Peyer's patch B cell](http://purl.obolibrary.org/obo/CL_0002402) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + + +### Peyer's patch follicular dendritic cell `http://purl.obolibrary.org/obo/CL_0009015` +#### Removed +- [Peyer's patch follicular dendritic cell](http://purl.obolibrary.org/obo/CL_0009015) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### Purkinje myocyte of atrioventricular bundle `http://purl.obolibrary.org/obo/CL_1000484` + +#### Added +- [Purkinje myocyte of atrioventricular bundle](http://purl.obolibrary.org/obo/CL_1000484) SubClassOf [transversely striated visceral muscle cell](http://purl.obolibrary.org/obo/CL_0008009) + + +### RNA biosynthetic process `http://purl.obolibrary.org/obo/GO_0032774` +#### Removed +- [RNA biosynthetic process](http://purl.obolibrary.org/obo/GO_0032774) SubClassOf [macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0009059) + +- [RNA biosynthetic process](http://purl.obolibrary.org/obo/GO_0032774) SubClassOf [nucleobase-containing compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0034654) + +#### Added +- [RNA biosynthetic process](http://purl.obolibrary.org/obo/GO_0032774) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [gocheck_do_not_annotate](http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate) + +- [RNA biosynthetic process](http://purl.obolibrary.org/obo/GO_0032774) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### RNA catabolic process `http://purl.obolibrary.org/obo/GO_0006401` +#### Removed +- [RNA catabolic process](http://purl.obolibrary.org/obo/GO_0006401) SubClassOf [nucleobase-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0034655) + +- [RNA catabolic process](http://purl.obolibrary.org/obo/GO_0006401) SubClassOf [cellular macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0044265) + +#### Added +- [RNA catabolic process](http://purl.obolibrary.org/obo/GO_0006401) SubClassOf [macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0009057) + + +### RNA metabolic process `http://purl.obolibrary.org/obo/GO_0016070` +#### Removed +- [RNA metabolic process](http://purl.obolibrary.org/obo/GO_0016070) SubClassOf [nucleic acid metabolic process](http://purl.obolibrary.org/obo/GO_0090304) + +#### Added +- [RNA metabolic process](http://purl.obolibrary.org/obo/GO_0016070) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### RNA transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0051033` +#### Removed +- [RNA transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051033) SubClassOf [nucleic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051032) + +#### Added +- [RNA transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051033) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + +### RNA transport `http://purl.obolibrary.org/obo/GO_0050658` +#### Removed +- [RNA transport](http://purl.obolibrary.org/obo/GO_0050658) SubClassOf [nucleic acid transport](http://purl.obolibrary.org/obo/GO_0050657) + +#### Added +- [RNA transport](http://purl.obolibrary.org/obo/GO_0050658) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### S cone cell `http://purl.obolibrary.org/obo/CL_0003050` + +#### Added +- [S cone cell](http://purl.obolibrary.org/obo/CL_0003050) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "S-(short-wavelength sensitive) cone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:31117170" + +- [S cone cell](http://purl.obolibrary.org/obo/CL_0003050) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "S cone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32555229" + +- [S cone cell](http://purl.obolibrary.org/obo/CL_0003050) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "short-wavelength-sensitive (S) cone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://opg.optica.org/josaa/abstract.cfm?URI=josaa-6-1-153" + +- [S cone cell](http://purl.obolibrary.org/obo/CL_0003050) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "S-cone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32555229" + +- [S cone cell](http://purl.obolibrary.org/obo/CL_0003050) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "short wavelength sensitive cone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:31117170" + +- [S cone cell](http://purl.obolibrary.org/obo/CL_0003050) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "short-wavelength sensitive cone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:31117170" + +- [S cone cell](http://purl.obolibrary.org/obo/CL_0003050) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "short- (S) wavelength-sensitive cone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://doi.org/10.7554/eLife.39166" + +- [S cone cell](http://purl.obolibrary.org/obo/CL_0003050) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "S-cone photoreceptor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://doi.org/10.7554/eLife.39166" + + +### SIRPa-negative adipose dendritic cell `http://purl.obolibrary.org/obo/CL_0002464` +#### Removed +- [SIRPa-negative adipose dendritic cell](http://purl.obolibrary.org/obo/CL_0002464) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [tyrosine-protein phosphatase non-receptor type substrate 1](http://purl.obolibrary.org/obo/PR_000001968)) + +- [SIRPa-negative adipose dendritic cell](http://purl.obolibrary.org/obo/CL_0002464) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [tyrosine-protein phosphatase non-receptor type substrate 1](http://purl.obolibrary.org/obo/PR_000001968) + +#### Added +- [SIRPa-negative adipose dendritic cell](http://purl.obolibrary.org/obo/CL_0002464) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [tyrosine-protein phosphatase non-receptor type substrate 1](http://purl.obolibrary.org/obo/PR_000001968)) + +- [SIRPa-negative adipose dendritic cell](http://purl.obolibrary.org/obo/CL_0002464) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [tyrosine-protein phosphatase non-receptor type substrate 1](http://purl.obolibrary.org/obo/PR_000001968) + + +### Saccharomyces cerevisiae metabolite `http://purl.obolibrary.org/obo/CHEBI_75772` +#### Removed +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Saccharomyces cerevisiae metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "baker's yeast metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) [label](http://www.w3.org/2000/01/rdf-schema#label) "Saccharomyces cerevisiae metabolite" + +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "baker's yeast secondary metabolite" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "baker's yeast secondary metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:76951" + +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "S. cerevisiae metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "S. cerevisiae secondary metabolite" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:75772" + +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:76949" + +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "baker's yeast metabolite" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Saccharomyces cerevisiae secondary metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae)." + +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "S. cerevisiae secondary metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "S. cerevisiae metabolite" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) + +- [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) SubClassOf [fungal metabolite](http://purl.obolibrary.org/obo/CHEBI_76946) + + + +### Slamf1-negative multipotent progenitor cell `http://purl.obolibrary.org/obo/CL_0002035` +#### Removed +- [Slamf1-negative multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002035) EquivalentTo [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001)) + +- [Slamf1-negative multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002035) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833) + +- [Slamf1-negative multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002035) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001) + +#### Added +- [Slamf1-negative multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002035) EquivalentTo [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) + +- [Slamf1-negative multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002035) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001) + +- [Slamf1-negative multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002035) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833) + + +### T cell `http://purl.obolibrary.org/obo/CL_0000084` +#### Removed +- [T cell](http://purl.obolibrary.org/obo/CL_0000084) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000804" + +- [T cell](http://purl.obolibrary.org/obo/CL_0000084) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000812" + + + +### T follicular helper cell `http://purl.obolibrary.org/obo/CL_0002038` +#### Removed +- [T follicular helper cell](http://purl.obolibrary.org/obo/CL_0002038) EquivalentTo [CD4-positive helper T cell](http://purl.obolibrary.org/obo/CL_0000492) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [B-cell lymphoma 6 protein](http://purl.obolibrary.org/obo/PR_000003450)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-X-C chemokine receptor type 5](http://purl.obolibrary.org/obo/PR_000001209)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [inducible T-cell costimulator](http://purl.obolibrary.org/obo/PR_000001860)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [programmed cell death protein 1](http://purl.obolibrary.org/obo/PR_000001919)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of isotype switching](http://purl.obolibrary.org/obo/GO_0045830)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [GO_0051024](http://purl.obolibrary.org/obo/GO_0051024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) + +- [T follicular helper cell](http://purl.obolibrary.org/obo/CL_0002038) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203) + +#### Added +- [T follicular helper cell](http://purl.obolibrary.org/obo/CL_0002038) EquivalentTo [CD4-positive helper T cell](http://purl.obolibrary.org/obo/CL_0000492) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [B-cell lymphoma 6 protein](http://purl.obolibrary.org/obo/PR_000003450)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-X-C chemokine receptor type 5](http://purl.obolibrary.org/obo/PR_000001209)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [inducible T-cell costimulator](http://purl.obolibrary.org/obo/PR_000001860)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [programmed cell death protein 1](http://purl.obolibrary.org/obo/PR_000001919)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of isotype switching](http://purl.obolibrary.org/obo/GO_0045830)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [GO_0051024](http://purl.obolibrary.org/obo/GO_0051024)) + +- [T follicular helper cell](http://purl.obolibrary.org/obo/CL_0002038) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203) + + +### T-helper 1 cell `http://purl.obolibrary.org/obo/CL_0000545` +#### Removed +- [T-helper 1 cell](http://purl.obolibrary.org/obo/CL_0000545) EquivalentTo [CD4-positive helper T cell](http://purl.obolibrary.org/obo/CL_0000492) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [T-box transcription factor TBX21](http://purl.obolibrary.org/obo/PR_000001835)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [type II interferon production](http://purl.obolibrary.org/obo/GO_0032609)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202)) + +- [T-helper 1 cell](http://purl.obolibrary.org/obo/CL_0000545) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202) + +#### Added +- [T-helper 1 cell](http://purl.obolibrary.org/obo/CL_0000545) EquivalentTo [CD4-positive helper T cell](http://purl.obolibrary.org/obo/CL_0000492) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [T-box transcription factor TBX21](http://purl.obolibrary.org/obo/PR_000001835)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [type II interferon production](http://purl.obolibrary.org/obo/GO_0032609)) + +- [T-helper 1 cell](http://purl.obolibrary.org/obo/CL_0000545) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202) + + +### T-helper 17 cell `http://purl.obolibrary.org/obo/CL_0000899` +#### Removed +- [T-helper 17 cell](http://purl.obolibrary.org/obo/CL_0000899) EquivalentTo [CD4-positive helper T cell](http://purl.obolibrary.org/obo/CL_0000492) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nuclear receptor ROR-gamma isoform 2](http://purl.obolibrary.org/obo/PR_000003455)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-17 production](http://purl.obolibrary.org/obo/GO_0032620)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207)) + +- [T-helper 17 cell](http://purl.obolibrary.org/obo/CL_0000899) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207) + +#### Added +- [T-helper 17 cell](http://purl.obolibrary.org/obo/CL_0000899) EquivalentTo [CD4-positive helper T cell](http://purl.obolibrary.org/obo/CL_0000492) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nuclear receptor ROR-gamma isoform 2](http://purl.obolibrary.org/obo/PR_000003455)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-17 production](http://purl.obolibrary.org/obo/GO_0032620)) + +- [T-helper 17 cell](http://purl.obolibrary.org/obo/CL_0000899) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207) + + +### T-helper 2 cell `http://purl.obolibrary.org/obo/CL_0000546` +#### Removed +- [T-helper 2 cell](http://purl.obolibrary.org/obo/CL_0000546) EquivalentTo [CD4-positive helper T cell](http://purl.obolibrary.org/obo/CL_0000492) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [trans-acting T-cell-specific transcription factor GATA-3](http://purl.obolibrary.org/obo/PR_000001941)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-4 production](http://purl.obolibrary.org/obo/GO_0032633)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207)) + +#### Added +- [T-helper 2 cell](http://purl.obolibrary.org/obo/CL_0000546) EquivalentTo [CD4-positive helper T cell](http://purl.obolibrary.org/obo/CL_0000492) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [trans-acting T-cell-specific transcription factor GATA-3](http://purl.obolibrary.org/obo/PR_000001941)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-4 production](http://purl.obolibrary.org/obo/GO_0032633)) + + +### T1 B cell `http://purl.obolibrary.org/obo/CL_0000958` +#### Removed +- [T1 B cell](http://purl.obolibrary.org/obo/CL_0000958) EquivalentTo [transitional stage B cell](http://purl.obolibrary.org/obo/CL_0000818) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880)) + +- [T1 B cell](http://purl.obolibrary.org/obo/CL_0000958) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338) + +- [T1 B cell](http://purl.obolibrary.org/obo/CL_0000958) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318) + +- [T1 B cell](http://purl.obolibrary.org/obo/CL_0000958) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738) + +- [T1 B cell](http://purl.obolibrary.org/obo/CL_0000958) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880) + +#### Added +- [T1 B cell](http://purl.obolibrary.org/obo/CL_0000958) EquivalentTo [transitional stage B cell](http://purl.obolibrary.org/obo/CL_0000818) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) + +- [T1 B cell](http://purl.obolibrary.org/obo/CL_0000958) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738) + +- [T1 B cell](http://purl.obolibrary.org/obo/CL_0000958) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880) + +- [T1 B cell](http://purl.obolibrary.org/obo/CL_0000958) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318) + +- [T1 B cell](http://purl.obolibrary.org/obo/CL_0000958) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338) + + +### T2 B cell `http://purl.obolibrary.org/obo/CL_0000959` +#### Removed +- [T2 B cell](http://purl.obolibrary.org/obo/CL_0000959) EquivalentTo [transitional stage B cell](http://purl.obolibrary.org/obo/CL_0000818) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) + +- [T2 B cell](http://purl.obolibrary.org/obo/CL_0000959) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318) + +#### Added +- [T2 B cell](http://purl.obolibrary.org/obo/CL_0000959) EquivalentTo [transitional stage B cell](http://purl.obolibrary.org/obo/CL_0000818) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) + +- [T2 B cell](http://purl.obolibrary.org/obo/CL_0000959) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318) + + +### Tc1 cell `http://purl.obolibrary.org/obo/CL_0000917` +#### Removed +- [Tc1 cell](http://purl.obolibrary.org/obo/CL_0000917) EquivalentTo [CD8-positive, alpha-beta cytokine secreting effector T cell](http://purl.obolibrary.org/obo/CL_0000908) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [T-box transcription factor TBX21](http://purl.obolibrary.org/obo/PR_000001835)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [eomesodermin](http://purl.obolibrary.org/obo/PR_000003463)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [type II interferon production](http://purl.obolibrary.org/obo/GO_0032609)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202)) + +- [Tc1 cell](http://purl.obolibrary.org/obo/CL_0000917) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202) + +#### Added +- [Tc1 cell](http://purl.obolibrary.org/obo/CL_0000917) EquivalentTo [CD8-positive, alpha-beta cytokine secreting effector T cell](http://purl.obolibrary.org/obo/CL_0000908) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [T-box transcription factor TBX21](http://purl.obolibrary.org/obo/PR_000001835)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [eomesodermin](http://purl.obolibrary.org/obo/PR_000003463)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [type II interferon production](http://purl.obolibrary.org/obo/GO_0032609)) + +- [Tc1 cell](http://purl.obolibrary.org/obo/CL_0000917) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202) + + +### Tc17 cell `http://purl.obolibrary.org/obo/CL_0002128` +#### Removed +- [Tc17 cell](http://purl.obolibrary.org/obo/CL_0002128) EquivalentTo [CD8-positive, alpha-beta cytokine secreting effector T cell](http://purl.obolibrary.org/obo/CL_0000908) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-17 production](http://purl.obolibrary.org/obo/GO_0032620)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [C-C chemokine receptor type 5](http://purl.obolibrary.org/obo/PR_000001201)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) + +- [Tc17 cell](http://purl.obolibrary.org/obo/CL_0002128) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + +#### Added +- [Tc17 cell](http://purl.obolibrary.org/obo/CL_0002128) EquivalentTo [CD8-positive, alpha-beta cytokine secreting effector T cell](http://purl.obolibrary.org/obo/CL_0000908) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-17 production](http://purl.obolibrary.org/obo/GO_0032620)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [C-C chemokine receptor type 5](http://purl.obolibrary.org/obo/PR_000001201)) + +- [Tc17 cell](http://purl.obolibrary.org/obo/CL_0002128) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + + +### Tc2 cell `http://purl.obolibrary.org/obo/CL_0000918` +#### Removed +- [Tc2 cell](http://purl.obolibrary.org/obo/CL_0000918) EquivalentTo [CD8-positive, alpha-beta cytokine secreting effector T cell](http://purl.obolibrary.org/obo/CL_0000908) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [trans-acting T-cell-specific transcription factor GATA-3](http://purl.obolibrary.org/obo/PR_000001941)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-4 production](http://purl.obolibrary.org/obo/GO_0032633)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207)) + +#### Added +- [Tc2 cell](http://purl.obolibrary.org/obo/CL_0000918) EquivalentTo [CD8-positive, alpha-beta cytokine secreting effector T cell](http://purl.obolibrary.org/obo/CL_0000908) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [trans-acting T-cell-specific transcription factor GATA-3](http://purl.obolibrary.org/obo/PR_000001941)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 6](http://purl.obolibrary.org/obo/PR_000001202)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-X-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001207)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-4 production](http://purl.obolibrary.org/obo/GO_0032633)) + + +### _STAR `http://purl.obolibrary.org/obo/chebi#1_STAR` +#### Removed +- AnnotationProperty: [_STAR](http://purl.obolibrary.org/obo/chebi#1_STAR) + +- [_STAR](http://purl.obolibrary.org/obo/chebi#1_STAR) SubPropertyOf: [subset_property](http://www.geneontology.org/formats/oboInOwl#SubsetProperty) + + + +### _STAR `http://purl.obolibrary.org/obo/chebi#2_STAR` +#### Removed +- AnnotationProperty: [_STAR](http://purl.obolibrary.org/obo/chebi#2_STAR) + +- [_STAR](http://purl.obolibrary.org/obo/chebi#2_STAR) SubPropertyOf: [subset_property](http://www.geneontology.org/formats/oboInOwl#SubsetProperty) + + + +### _STAR `http://purl.obolibrary.org/obo/chebi#3_STAR` +#### Removed +- AnnotationProperty: [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) SubPropertyOf: [subset_property](http://www.geneontology.org/formats/oboInOwl#SubsetProperty) + + + +### acceptor `http://purl.obolibrary.org/obo/CHEBI_15339` +#### Removed +- [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Akzeptor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Oxidized donor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "accepteur" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:2377" + +- [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13699" + +- [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) [label](http://www.w3.org/2000/01/rdf-schema#label) "acceptor" + +- [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00028" + +- [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity." + +- [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:15339" + +- [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Hydrogen-acceptor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Acceptor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C16722" + +- [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "A" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) + +- [acceptor](http://purl.obolibrary.org/obo/CHEBI_15339) SubClassOf [chemical role](http://purl.obolibrary.org/obo/CHEBI_51086) + + + +### acetamides `http://purl.obolibrary.org/obo/CHEBI_22160` +#### Removed +- [acetamides](http://purl.obolibrary.org/obo/CHEBI_22160) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [acetamides](http://purl.obolibrary.org/obo/CHEBI_22160) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Compounds with the general formula RNHC(=O)CH3." + +- [acetamides](http://purl.obolibrary.org/obo/CHEBI_22160) [label](http://www.w3.org/2000/01/rdf-schema#label) "acetamides" + +- [acetamides](http://purl.obolibrary.org/obo/CHEBI_22160) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:22160" + +- [acetamides](http://purl.obolibrary.org/obo/CHEBI_22160) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [acetamides](http://purl.obolibrary.org/obo/CHEBI_22160) + +- [acetamides](http://purl.obolibrary.org/obo/CHEBI_22160) SubClassOf [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) + + + +### acetate `http://purl.obolibrary.org/obo/CHEBI_30089` +#### Removed +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ACETATE ION" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ethanoate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:ACT" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22371380" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00033" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "59.01385" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [label](http://www.w3.org/2000/01/rdf-schema#label) "acetate" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "CC([O-])=O" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acetic acid, ion(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UM-BBD_compID:c0050" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "UM-BBD" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17190852" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:1379" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:71-50-1" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:40480" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22165" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB03166" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:ACET" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22211106" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "MeCO2 anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [mass](http://purl.obolibrary.org/obo/chebi/mass) "59.04402" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Azetat" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CH3-COO(-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Acetate" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "QTBSBXVTEAMEQO-UHFFFAOYSA-M" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:1901470" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid." + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13704" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:30089" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:1901470" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2H3O2" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:71-50-1" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ethanoat" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) SubClassOf [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) + +- [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + + + +### acetate biosynthetic process `http://purl.obolibrary.org/obo/GO_0019413` +#### Removed +- [acetate biosynthetic process](http://purl.obolibrary.org/obo/GO_0019413) [label](http://www.w3.org/2000/01/rdf-schema#label) "acetate biosynthetic process" + +- [acetate biosynthetic process](http://purl.obolibrary.org/obo/GO_0019413) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0019413" + +- [acetate biosynthetic process](http://purl.obolibrary.org/obo/GO_0019413) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetate biosynthesis" + +- [acetate biosynthetic process](http://purl.obolibrary.org/obo/GO_0019413) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetate anabolism" + +- [acetate biosynthetic process](http://purl.obolibrary.org/obo/GO_0019413) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetate synthesis" + +- [acetate biosynthetic process](http://purl.obolibrary.org/obo/GO_0019413) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetate formation" + +- [acetate biosynthetic process](http://purl.obolibrary.org/obo/GO_0019413) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [acetate biosynthetic process](http://purl.obolibrary.org/obo/GO_0019413) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- Class: [acetate biosynthetic process](http://purl.obolibrary.org/obo/GO_0019413) + +- [acetate biosynthetic process](http://purl.obolibrary.org/obo/GO_0019413) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089)) + +- [acetate biosynthetic process](http://purl.obolibrary.org/obo/GO_0019413) SubClassOf [monocarboxylic acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0072330) + +- [acetate biosynthetic process](http://purl.obolibrary.org/obo/GO_0019413) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) + +- [acetate biosynthetic process](http://purl.obolibrary.org/obo/GO_0019413) SubClassOf [acetate metabolic process](http://purl.obolibrary.org/obo/GO_0006083) + + + +### acetate catabolic process `http://purl.obolibrary.org/obo/GO_0045733` +#### Removed +- [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetate catabolism" + +- [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetate degradation" + +- [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0045733" + +- [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetate breakdown" + +- [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0019663" + +- [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "homoacetate catabolic process" + +- [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733) [label](http://www.w3.org/2000/01/rdf-schema#label) "acetate catabolic process" + +- [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- Class: [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733) + +- [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089)) + +- [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733) SubClassOf [acetate metabolic process](http://purl.obolibrary.org/obo/GO_0006083) + +- [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733) SubClassOf [monocarboxylic acid catabolic process](http://purl.obolibrary.org/obo/GO_0072329) + +- [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) + + + +### acetate ester `http://purl.obolibrary.org/obo/CHEBI_47622` +#### Removed +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acetyl esters" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Acetic ester" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "C2H3O2R" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [FORMULA](http://purl.obolibrary.org/obo/fbbt#FORMULA) + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acetate esters" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acetate esters" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acetyl esters" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22189" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13799" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Acetic ester" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "an acetyl ester" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2H3O2R" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "59.01330" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acetates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Acetyl ester" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acetates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:47622" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:2406" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acetate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Acetate#Esters" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01883" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acetyl ester" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt:" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any carboxylic ester where the carboxylic acid component is acetic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [mass](http://purl.obolibrary.org/obo/chebi/mass) "59.04400" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "CC(=O)O[*]" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13244" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [label](http://www.w3.org/2000/01/rdf-schema#label) "acetate ester" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acetate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Acetyl ester" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- Class: [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) SubClassOf [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) + +- [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) + + + +### acetate ester biosynthetic process `http://purl.obolibrary.org/obo/GO_1900620` +#### Removed +- [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "bf" + +- [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetate ester formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetate ester synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) [label](http://www.w3.org/2000/01/rdf-schema#label) "acetate ester biosynthetic process" + +- [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetyl ester biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CHEBI:47622" + +- [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1900620" + +- [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetate ester biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-05-16T12:30:12Z" + +- [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetyl ester biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CHEBI:47622" + +- [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetate ester anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of an acetate esteran acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15042596" + +- Class: [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) + +- [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622)) + +- [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) + +- [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) SubClassOf [organic substance biosynthetic process](http://purl.obolibrary.org/obo/GO_1901576) + +- [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) SubClassOf [acetate ester metabolic process](http://purl.obolibrary.org/obo/GO_1900619) + + + +### acetate ester metabolic process `http://purl.obolibrary.org/obo/GO_1900619` +#### Removed +- [acetate ester metabolic process](http://purl.obolibrary.org/obo/GO_1900619) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [acetate ester metabolic process](http://purl.obolibrary.org/obo/GO_1900619) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1900619" + +- [acetate ester metabolic process](http://purl.obolibrary.org/obo/GO_1900619) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetyl ester metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CHEBI:47622" + +- [acetate ester metabolic process](http://purl.obolibrary.org/obo/GO_1900619) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [acetate ester metabolic process](http://purl.obolibrary.org/obo/GO_1900619) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetyl ester metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CHEBI:47622" + +- [acetate ester metabolic process](http://purl.obolibrary.org/obo/GO_1900619) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "bf" + +- [acetate ester metabolic process](http://purl.obolibrary.org/obo/GO_1900619) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetate ester metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [acetate ester metabolic process](http://purl.obolibrary.org/obo/GO_1900619) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-05-16T12:29:51Z" + +- [acetate ester metabolic process](http://purl.obolibrary.org/obo/GO_1900619) [label](http://www.w3.org/2000/01/rdf-schema#label) "acetate ester metabolic process" + +- Class: [acetate ester metabolic process](http://purl.obolibrary.org/obo/GO_1900619) + +- [acetate ester metabolic process](http://purl.obolibrary.org/obo/GO_1900619) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622)) + +- [acetate ester metabolic process](http://purl.obolibrary.org/obo/GO_1900619) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) + +- [acetate ester metabolic process](http://purl.obolibrary.org/obo/GO_1900619) SubClassOf [organic substance metabolic process](http://purl.obolibrary.org/obo/GO_0071704) + + + +### acetate ester metabolic process involved in fermentation `http://purl.obolibrary.org/obo/GO_1901089` +#### Removed +- [acetate ester metabolic process involved in fermentation](http://purl.obolibrary.org/obo/GO_1901089) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [acetate ester metabolic process involved in fermentation](http://purl.obolibrary.org/obo/GO_1901089) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-07-05T11:47:17Z" + +- [acetate ester metabolic process involved in fermentation](http://purl.obolibrary.org/obo/GO_1901089) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901089" + +- [acetate ester metabolic process involved in fermentation](http://purl.obolibrary.org/obo/GO_1901089) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any acetate ester metabolic process that is involved in fermentation." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:sgd_curators" + +- [acetate ester metabolic process involved in fermentation](http://purl.obolibrary.org/obo/GO_1901089) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetate ester metabolic process during fermentation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:sgd_curators" + +- [acetate ester metabolic process involved in fermentation](http://purl.obolibrary.org/obo/GO_1901089) [label](http://www.w3.org/2000/01/rdf-schema#label) "acetate ester metabolic process involved in fermentation" + +- [acetate ester metabolic process involved in fermentation](http://purl.obolibrary.org/obo/GO_1901089) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "rb" + +- Class: [acetate ester metabolic process involved in fermentation](http://purl.obolibrary.org/obo/GO_1901089) + +- [acetate ester metabolic process involved in fermentation](http://purl.obolibrary.org/obo/GO_1901089) EquivalentTo [acetate ester metabolic process](http://purl.obolibrary.org/obo/GO_1900619) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [fermentation](http://purl.obolibrary.org/obo/GO_0006113)) + +- [acetate ester metabolic process involved in fermentation](http://purl.obolibrary.org/obo/GO_1901089) SubClassOf [acetate ester metabolic process](http://purl.obolibrary.org/obo/GO_1900619) + +- [acetate ester metabolic process involved in fermentation](http://purl.obolibrary.org/obo/GO_1901089) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [fermentation](http://purl.obolibrary.org/obo/GO_0006113) + + + +### acetate ester transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_1901375` +#### Removed +- [acetate ester transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901375) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-09-28T10:47:08Z" + +- [acetate ester transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901375) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "bf" + +- [acetate ester transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901375) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [acetate ester transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901375) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of an acetate ester from one side of a membrane to the other." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [acetate ester transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901375) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901375" + +- [acetate ester transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901375) [label](http://www.w3.org/2000/01/rdf-schema#label) "acetate ester transmembrane transporter activity" + +- Class: [acetate ester transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901375) + +- [acetate ester transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901375) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622)) + +- [acetate ester transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901375) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + +- [acetate ester transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901375) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [acetate ester transport](http://purl.obolibrary.org/obo/GO_1901374) + +- [acetate ester transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901375) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) + + + +### acetate ester transport `http://purl.obolibrary.org/obo/GO_1901374` +#### Removed +- [acetate ester transport](http://purl.obolibrary.org/obo/GO_1901374) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [acetate ester transport](http://purl.obolibrary.org/obo/GO_1901374) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-09-28T10:42:13Z" + +- [acetate ester transport](http://purl.obolibrary.org/obo/GO_1901374) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [acetate ester transport](http://purl.obolibrary.org/obo/GO_1901374) [label](http://www.w3.org/2000/01/rdf-schema#label) "acetate ester transport" + +- [acetate ester transport](http://purl.obolibrary.org/obo/GO_1901374) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "bf" + +- [acetate ester transport](http://purl.obolibrary.org/obo/GO_1901374) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901374" + +- Class: [acetate ester transport](http://purl.obolibrary.org/obo/GO_1901374) + +- [acetate ester transport](http://purl.obolibrary.org/obo/GO_1901374) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622)) + +- [acetate ester transport](http://purl.obolibrary.org/obo/GO_1901374) SubClassOf [organic substance transport](http://purl.obolibrary.org/obo/GO_0071702) + +- [acetate ester transport](http://purl.obolibrary.org/obo/GO_1901374) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) + + + +### acetate fermentation `http://purl.obolibrary.org/obo/GO_0019654` +#### Removed +- [acetate fermentation](http://purl.obolibrary.org/obo/GO_0019654) [never in taxon](http://purl.obolibrary.org/obo/RO_0002161) [Schizosaccharomyces](http://purl.obolibrary.org/obo/NCBITaxon_4895) + +- [acetate fermentation](http://purl.obolibrary.org/obo/GO_0019654) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0019654" + +- [acetate fermentation](http://purl.obolibrary.org/obo/GO_0019654) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The anaerobic chemical reactions and pathways resulting in the breakdown of acetate, yielding energy in the form of ATP." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:P142-PWY" + +- [acetate fermentation](http://purl.obolibrary.org/obo/GO_0019654) [label](http://www.w3.org/2000/01/rdf-schema#label) "acetate fermentation" + +- [acetate fermentation](http://purl.obolibrary.org/obo/GO_0019654) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:P142-PWY" + +- [acetate fermentation](http://purl.obolibrary.org/obo/GO_0019654) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [acetate fermentation](http://purl.obolibrary.org/obo/GO_0019654) + +- [acetate fermentation](http://purl.obolibrary.org/obo/GO_0019654) DisjointWith [in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Schizosaccharomyces](http://purl.obolibrary.org/obo/NCBITaxon_4895) + +- [acetate fermentation](http://purl.obolibrary.org/obo/GO_0019654) EquivalentTo [fermentation](http://purl.obolibrary.org/obo/GO_0006113) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089)) + +- [acetate fermentation](http://purl.obolibrary.org/obo/GO_0019654) SubClassOf [acetate metabolic process](http://purl.obolibrary.org/obo/GO_0006083) + +- [acetate fermentation](http://purl.obolibrary.org/obo/GO_0019654) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) + +- [acetate fermentation](http://purl.obolibrary.org/obo/GO_0019654) SubClassOf [in taxon](http://purl.obolibrary.org/obo/RO_0002162) some (not ([Schizosaccharomyces](http://purl.obolibrary.org/obo/NCBITaxon_4895))) + +- [acetate fermentation](http://purl.obolibrary.org/obo/GO_0019654) SubClassOf not ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Schizosaccharomyces](http://purl.obolibrary.org/obo/NCBITaxon_4895)) + +- [acetate fermentation](http://purl.obolibrary.org/obo/GO_0019654) SubClassOf [fermentation](http://purl.obolibrary.org/obo/GO_0006113) + + + +### acetate metabolic process `http://purl.obolibrary.org/obo/GO_0006083` +#### Removed +- [acetate metabolic process](http://purl.obolibrary.org/obo/GO_0006083) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [acetate metabolic process](http://purl.obolibrary.org/obo/GO_0006083) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving acetate, the anion of acetic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [acetate metabolic process](http://purl.obolibrary.org/obo/GO_0006083) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetate metabolism" + +- [acetate metabolic process](http://purl.obolibrary.org/obo/GO_0006083) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006083" + +- [acetate metabolic process](http://purl.obolibrary.org/obo/GO_0006083) [label](http://www.w3.org/2000/01/rdf-schema#label) "acetate metabolic process" + +- Class: [acetate metabolic process](http://purl.obolibrary.org/obo/GO_0006083) + +- [acetate metabolic process](http://purl.obolibrary.org/obo/GO_0006083) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089)) + +- [acetate metabolic process](http://purl.obolibrary.org/obo/GO_0006083) SubClassOf [monocarboxylic acid metabolic process](http://purl.obolibrary.org/obo/GO_0032787) + +- [acetate metabolic process](http://purl.obolibrary.org/obo/GO_0006083) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) + + + +### acetate transmembrane transport `http://purl.obolibrary.org/obo/GO_0035433` +#### Removed +- [acetate transmembrane transport](http://purl.obolibrary.org/obo/GO_0035433) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [acetate transmembrane transport](http://purl.obolibrary.org/obo/GO_0035433) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "bf" + +- [acetate transmembrane transport](http://purl.obolibrary.org/obo/GO_0035433) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetate membrane transport" + +- [acetate transmembrane transport](http://purl.obolibrary.org/obo/GO_0035433) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0035433" + +- [acetate transmembrane transport](http://purl.obolibrary.org/obo/GO_0035433) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Note that this term is not intended for use in annotating lateral movement within membranes." + +- [acetate transmembrane transport](http://purl.obolibrary.org/obo/GO_0035433) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-04-08T10:59:01Z" + +- [acetate transmembrane transport](http://purl.obolibrary.org/obo/GO_0035433) [label](http://www.w3.org/2000/01/rdf-schema#label) "acetate transmembrane transport" + +- [acetate transmembrane transport](http://purl.obolibrary.org/obo/GO_0035433) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:vw" + +- Class: [acetate transmembrane transport](http://purl.obolibrary.org/obo/GO_0035433) + +- [acetate transmembrane transport](http://purl.obolibrary.org/obo/GO_0035433) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([results in transport across](http://purl.obolibrary.org/obo/RO_0002342) some [membrane](http://purl.obolibrary.org/obo/GO_0016020)) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089)) + +- [acetate transmembrane transport](http://purl.obolibrary.org/obo/GO_0035433) SubClassOf [acetate transport](http://purl.obolibrary.org/obo/GO_0006846) + +- [acetate transmembrane transport](http://purl.obolibrary.org/obo/GO_0035433) SubClassOf [carboxylic acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1905039) + + + +### acetate transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015123` +#### Removed +- [acetate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015123) [label](http://www.w3.org/2000/01/rdf-schema#label) "acetate transmembrane transporter activity" + +- [acetate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015123) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015123" + +- [acetate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015123) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [acetate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015123) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- Class: [acetate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015123) + +- [acetate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015123) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089)) + +- [acetate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015123) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) + +- [acetate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015123) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [acetate transmembrane transport](http://purl.obolibrary.org/obo/GO_0035433) + - [source](http://www.geneontology.org/formats/oboInOwl#http://purl.org/dc/terms/source) "GO_REF:0000090" + +- [acetate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015123) SubClassOf [carboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046943) + + + +### acetate transport `http://purl.obolibrary.org/obo/GO_0006846` +#### Removed +- [acetate transport](http://purl.obolibrary.org/obo/GO_0006846) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [acetate transport](http://purl.obolibrary.org/obo/GO_0006846) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006846" + +- [acetate transport](http://purl.obolibrary.org/obo/GO_0006846) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [acetate transport](http://purl.obolibrary.org/obo/GO_0006846) [label](http://www.w3.org/2000/01/rdf-schema#label) "acetate transport" + +- Class: [acetate transport](http://purl.obolibrary.org/obo/GO_0006846) + +- [acetate transport](http://purl.obolibrary.org/obo/GO_0006846) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089)) + +- [acetate transport](http://purl.obolibrary.org/obo/GO_0006846) SubClassOf [monocarboxylic acid transport](http://purl.obolibrary.org/obo/GO_0015718) + +- [acetate transport](http://purl.obolibrary.org/obo/GO_0006846) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) + + + +### acetic acid `http://purl.obolibrary.org/obo/CHEBI_15366` +#### Removed +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:1380" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "QTBSBXVTEAMEQO-UHFFFAOYSA-N" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16630552" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "AcOH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A simple monocarboxylic acid containing two carbons." + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ACETIC ACID" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:2387" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12005138" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00001176" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CH3CO2H" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PPDB:1333" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:ACY" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:4211" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "E-260" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [label](http://www.w3.org/2000/01/rdf-schema#label) "acetic acid" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:ACET" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:40486" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Acetic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:ACT" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D00010" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2H4O2" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16774200" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00033" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22173419" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "CC(O)=O" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Acetic_acid" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000042" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "INS No. 260" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "E260" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ethanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:64-19-7" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CH3-COOH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ethylic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:506007" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15107950" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:506007" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17190852" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:15366" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "60.02113" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:64-19-7" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acide acetique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HOAc" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "MeCO2H" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19416101" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "E 260" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19469536" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ethoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22153255" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22169" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Methanecarboxylic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [mass](http://purl.obolibrary.org/obo/chebi/mass) "60.05200" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Essigsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "MeCOOH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:64-19-7" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LIPID_MAPS_instance:LMFA01010002" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "LIPID MAPS" + +- Class: [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [antimicrobial food preservative](http://purl.obolibrary.org/obo/CHEBI_65256) + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) SubClassOf [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [food acidity regulator](http://purl.obolibrary.org/obo/CHEBI_64049) + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [protic solvent](http://purl.obolibrary.org/obo/CHEBI_48356) + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) + +- [acetic acid](http://purl.obolibrary.org/obo/CHEBI_15366) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Daphnia magna metabolite](http://purl.obolibrary.org/obo/CHEBI_83056) + + + +### acetylcholine `http://purl.obolibrary.org/obo/CHEBI_15355` +#### Removed +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "146.11756" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LINCS:LSM-5888" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acetylcholine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:ACH" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:326108" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "CC(=O)OCC[N+](C)(C)C" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ACETYLCHOLINE" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:51-84-3" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "OIPILFWXSMYKGL-UHFFFAOYSA-N" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Acetylcholine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:14764638" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19255787" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C7H16NO2" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:51-84-3" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "O-Acetylcholine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB03128" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "choline acetate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15231705" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13715" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18407448" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22197" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:1764436" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18050502" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01996" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21545631" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15014918" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21130809" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [mass](http://purl.obolibrary.org/obo/chebi/mass) "146.20748" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:40559" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20963497" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "2-acetyloxy-N,N,N-trimethylethanaminium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Azetylcholin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:65" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [label](http://www.w3.org/2000/01/rdf-schema#label) "acetylcholine" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21246223" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+1" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ACh" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:12686" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Acetylcholine" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21601579" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:2416" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15361288" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [hormone](http://purl.obolibrary.org/obo/CHEBI_24621) + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [neurotransmitter](http://purl.obolibrary.org/obo/CHEBI_25512) + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) SubClassOf [acetate ester](http://purl.obolibrary.org/obo/CHEBI_47622) + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [muscarinic agonist](http://purl.obolibrary.org/obo/CHEBI_38325) + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) SubClassOf [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [acetylcholine](http://purl.obolibrary.org/obo/CHEBI_15355) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [vasodilator agent](http://purl.obolibrary.org/obo/CHEBI_35620) + + + +### acetylcholine binding `http://purl.obolibrary.org/obo/GO_0042166` +#### Removed +- [acetylcholine binding](http://purl.obolibrary.org/obo/GO_0042166) SubClassOf [cation binding](http://purl.obolibrary.org/obo/GO_0043169) + + + +### acetylcholine biosynthetic process `http://purl.obolibrary.org/obo/GO_0008292` +#### Removed +- [acetylcholine biosynthetic process](http://purl.obolibrary.org/obo/GO_0008292) SubClassOf [acetate ester biosynthetic process](http://purl.obolibrary.org/obo/GO_1900620) + + + +### acetylcholine catabolic process `http://purl.obolibrary.org/obo/GO_0006581` +#### Removed +- [acetylcholine catabolic process](http://purl.obolibrary.org/obo/GO_0006581) SubClassOf [organic substance catabolic process](http://purl.obolibrary.org/obo/GO_1901575) + + + +### acetylcholine metabolic process `http://purl.obolibrary.org/obo/GO_0008291` +#### Removed +- [acetylcholine metabolic process](http://purl.obolibrary.org/obo/GO_0008291) SubClassOf [acetate ester metabolic process](http://purl.obolibrary.org/obo/GO_1900619) + +- [acetylcholine metabolic process](http://purl.obolibrary.org/obo/GO_0008291) SubClassOf [nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0006807) + + + +### acetylcholine transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0005277` +#### Removed +- [acetylcholine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005277) SubClassOf [acetate ester transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901375) + +- [acetylcholine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005277) SubClassOf [organic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015101) + +#### Added +- [acetylcholine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005277) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + +### acetylcholine transport `http://purl.obolibrary.org/obo/GO_0015870` +#### Removed +- [acetylcholine transport](http://purl.obolibrary.org/obo/GO_0015870) SubClassOf [nitrogen compound transport](http://purl.obolibrary.org/obo/GO_0071705) + +- [acetylcholine transport](http://purl.obolibrary.org/obo/GO_0015870) SubClassOf [acetate ester transport](http://purl.obolibrary.org/obo/GO_1901374) + +- [acetylcholine transport](http://purl.obolibrary.org/obo/GO_0015870) SubClassOf [organic cation transport](http://purl.obolibrary.org/obo/GO_0015695) + +#### Added +- [acetylcholine transport](http://purl.obolibrary.org/obo/GO_0015870) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### acetylcholine uptake `http://purl.obolibrary.org/obo/GO_0051630` +#### Removed +- [acetylcholine uptake](http://purl.obolibrary.org/obo/GO_0051630) SubClassOf [import into cell](http://purl.obolibrary.org/obo/GO_0098657) + +#### Added +- [acetylcholine uptake](http://purl.obolibrary.org/obo/GO_0051630) SubClassOf [has target end location](http://purl.obolibrary.org/obo/RO_0002339) some [intracellular anatomical structure](http://purl.obolibrary.org/obo/GO_0005622) + +- [acetylcholine uptake](http://purl.obolibrary.org/obo/GO_0051630) SubClassOf [has target start location](http://purl.obolibrary.org/obo/RO_0002338) some [extracellular region](http://purl.obolibrary.org/obo/GO_0005576) + + +### acid `http://purl.obolibrary.org/obo/CHEBI_37527` +#### Removed +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Saeuren" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acido" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00174" + +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22209" + +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid)." + +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13800" + +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Saeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:2426" + +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:37527" + +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13801" + +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) [label](http://www.w3.org/2000/01/rdf-schema#label) "acid" + +- Class: [acid](http://purl.obolibrary.org/obo/CHEBI_37527) + +- [acid](http://purl.obolibrary.org/obo/CHEBI_37527) SubClassOf [chemical role](http://purl.obolibrary.org/obo/CHEBI_51086) + + + +### acidic amino acid transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015172` + +#### Added +- [acidic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015172) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0815340729" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_transport" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [acidic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015172) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015172" + +- [acidic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015172) [label](http://www.w3.org/2000/01/rdf-schema#label) "acidic amino acid transmembrane transporter activity" + +- [acidic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015172) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "acidic amino acid transporter activity" + +- [acidic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015172) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-372448" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "SLC25A12,13 exchange cytosolic L-Glu for mitochondrial matrix L-Asp" + +- [acidic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015172) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- Class: [acidic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015172) + +- [acidic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015172) SubClassOf [amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015171) + +- [acidic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015172) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [acidic amino acid transport](http://purl.obolibrary.org/obo/GO_0015800) + + +### acinar cell of sebaceous gland `http://purl.obolibrary.org/obo/CL_0002140` +#### Removed +- [acinar cell of sebaceous gland](http://purl.obolibrary.org/obo/CL_0002140) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0002587" + + + +### activated CD4-negative, CD8-negative type I NK T cell `http://purl.obolibrary.org/obo/CL_0000928` +#### Removed +- [activated CD4-negative, CD8-negative type I NK T cell](http://purl.obolibrary.org/obo/CL_0000928) EquivalentTo [type I NK T cell](http://purl.obolibrary.org/obo/CL_0000921) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD69 molecule](http://purl.obolibrary.org/obo/PR_000001343)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [T cell cytokine production](http://purl.obolibrary.org/obo/GO_0002369)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +#### Added +- [activated CD4-negative, CD8-negative type I NK T cell](http://purl.obolibrary.org/obo/CL_0000928) EquivalentTo [type I NK T cell](http://purl.obolibrary.org/obo/CL_0000921) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD69 molecule](http://purl.obolibrary.org/obo/PR_000001343)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [T cell cytokine production](http://purl.obolibrary.org/obo/GO_0002369)) + + +### activated CD4-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000896` +#### Removed +- [activated CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000896) EquivalentTo [CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000624) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD69 molecule](http://purl.obolibrary.org/obo/PR_000001343)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) + +- [activated CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000896) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318) + +- [activated CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000896) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +#### Added +- [activated CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000896) EquivalentTo [CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000624) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD69 molecule](http://purl.obolibrary.org/obo/PR_000001343)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) + +- [activated CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000896) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318) + +- [activated CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000896) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + + +### activated CD8-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000906` +#### Removed +- [activated CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000906) EquivalentTo [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD69 molecule](http://purl.obolibrary.org/obo/PR_000001343)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) + +- [activated CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000906) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318) + +- [activated CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000906) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203) + +- [activated CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000906) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +#### Added +- [activated CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000906) EquivalentTo [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD69 molecule](http://purl.obolibrary.org/obo/PR_000001343)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) + +- [activated CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000906) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318) + +- [activated CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000906) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203) + +- [activated CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000906) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + + +### active monoatomic ion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0022853` +#### Removed +- [active monoatomic ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022853) [label](http://www.w3.org/2000/01/rdf-schema#label) "active monoatomic ion transmembrane transporter activity" + +- [active monoatomic ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022853) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0815340729" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_transport" + +- [active monoatomic ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022853) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24479"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [active monoatomic ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022853) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [active monoatomic ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022853) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0022853" + +- [active monoatomic ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022853) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "active ion transmembrane transporter activity" + +- Class: [active monoatomic ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022853) + +- [active monoatomic ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022853) EquivalentTo [active transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022804) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [monoatomic ion](http://purl.obolibrary.org/obo/CHEBI_24867)) + +- [active monoatomic ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022853) SubClassOf [active transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022804) + +- [active monoatomic ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022853) SubClassOf [monoatomic ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015075) + + + +### active transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0022804` +#### Removed +- [active transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022804) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carrier activity" + +- [active transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022804) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "active carrier activity" + +- [active transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022804) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0022804" + +- [active transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022804) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0815340729" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_transport" + +- [active transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022804) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [active transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022804) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "permease activity" + +- [active transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022804) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pump activity" + +- [active transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022804) [label](http://www.w3.org/2000/01/rdf-schema#label) "active transmembrane transporter activity" + +- Class: [active transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022804) + +- [active transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022804) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + + +### acts upstream of or within, negative effect `http://purl.obolibrary.org/obo/RO_0004033` +#### Removed +- [acts upstream of or within, negative effect](http://purl.obolibrary.org/obo/RO_0004033) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "cjm" + +#### Added +- [acts upstream of or within, negative effect](http://purl.obolibrary.org/obo/RO_0004033) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### acts upstream of or within, positive effect `http://purl.obolibrary.org/obo/RO_0004032` +#### Removed +- [acts upstream of or within, positive effect](http://purl.obolibrary.org/obo/RO_0004032) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "cjm" + +#### Added +- [acts upstream of or within, positive effect](http://purl.obolibrary.org/obo/RO_0004032) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### acts upstream of, negative effect `http://purl.obolibrary.org/obo/RO_0004035` +#### Removed +- [acts upstream of, negative effect](http://purl.obolibrary.org/obo/RO_0004035) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "cjm" + +#### Added +- [acts upstream of, negative effect](http://purl.obolibrary.org/obo/RO_0004035) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### acts upstream of, positive effect `http://purl.obolibrary.org/obo/RO_0004034` +#### Removed +- [acts upstream of, positive effect](http://purl.obolibrary.org/obo/RO_0004034) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "cjm" + +#### Added +- [acts upstream of, positive effect](http://purl.obolibrary.org/obo/RO_0004034) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### acyl binding `http://purl.obolibrary.org/obo/GO_0000035` +#### Removed +- [acyl binding](http://purl.obolibrary.org/obo/GO_0000035) [label](http://www.w3.org/2000/01/rdf-schema#label) "acyl binding" + +- [acyl binding](http://purl.obolibrary.org/obo/GO_0000035) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [acyl binding](http://purl.obolibrary.org/obo/GO_0000035) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:curators" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [acyl binding](http://purl.obolibrary.org/obo/GO_0000035) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "acyl-CoA or acyl binding" + +- [acyl binding](http://purl.obolibrary.org/obo/GO_0000035) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0000035" + +- Class: [acyl binding](http://purl.obolibrary.org/obo/GO_0000035) + +- [acyl binding](http://purl.obolibrary.org/obo/GO_0000035) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [acyl group](http://purl.obolibrary.org/obo/CHEBI_22221)) + +- [acyl binding](http://purl.obolibrary.org/obo/GO_0000035) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + +- [acyl binding](http://purl.obolibrary.org/obo/GO_0000035) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [acyl group](http://purl.obolibrary.org/obo/CHEBI_22221) + + + +### acyl group `http://purl.obolibrary.org/obo/CHEBI_22221` +#### Removed +- [acyl group](http://purl.obolibrary.org/obo/CHEBI_22221) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acyl groups" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acyl group](http://purl.obolibrary.org/obo/CHEBI_22221) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkanoyl" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [acyl group](http://purl.obolibrary.org/obo/CHEBI_22221) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [acyl group](http://purl.obolibrary.org/obo/CHEBI_22221) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [acyl group](http://purl.obolibrary.org/obo/CHEBI_22221) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alkanoyl group" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acyl group](http://purl.obolibrary.org/obo/CHEBI_22221) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:22221" + +- [acyl group](http://purl.obolibrary.org/obo/CHEBI_22221) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids." + +- [acyl group](http://purl.obolibrary.org/obo/CHEBI_22221) [label](http://www.w3.org/2000/01/rdf-schema#label) "acyl group" + +- [acyl group](http://purl.obolibrary.org/obo/CHEBI_22221) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "groupe acyle" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [acyl group](http://purl.obolibrary.org/obo/CHEBI_22221) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acyl group" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- Class: [acyl group](http://purl.obolibrary.org/obo/CHEBI_22221) + +- [acyl group](http://purl.obolibrary.org/obo/CHEBI_22221) SubClassOf [organic group](http://purl.obolibrary.org/obo/CHEBI_33247) + + + +### acylcholine `http://purl.obolibrary.org/obo/CHEBI_35287` +#### Removed +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acylcholines" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acylcholine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt:" + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [label](http://www.w3.org/2000/01/rdf-schema#label) "acylcholine" + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "C[N+](C)(C)CCOC([*])=O" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [SMILES](http://purl.obolibrary.org/obo/fbbt#SMILES) + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01777" + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C[N+](C)(C)CCOC([*])=O" + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [mass](http://purl.obolibrary.org/obo/chebi/mass) "131.17290" + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:2463" + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A choline ester formed from choline and a carboxylic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35287" + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+1" + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "an acylcholine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C6H13NO2R" + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acylcholines" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "131.09463" + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13245" + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "C6H13NO2R" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [FORMULA](http://purl.obolibrary.org/obo/fbbt#FORMULA) + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22227" + +- Class: [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) + +- [acylcholine](http://purl.obolibrary.org/obo/CHEBI_35287) SubClassOf [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) + + + +### acyltransferase activity `http://purl.obolibrary.org/obo/GO_0016746` + +#### Added +- [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-159431" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine" + +- [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_drosophila](http://purl.obolibrary.org/obo/go#goslim_drosophila) + +- [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0016746" + +- [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EC:2.3.-.-" + +- [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0008415" + +- [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "transferase activity, transferring acyl groups" + +- [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/20486"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_chembl](http://purl.obolibrary.org/obo/go#goslim_chembl) + +- [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-6792572" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs" + +- [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) [label](http://www.w3.org/2000/01/rdf-schema#label) "acyltransferase activity" + +- [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-193491" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate" + +- [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-192312" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate" + +- [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-8858298" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "HRASLS transfer acyl group from PC to PE to form NAPE" + +- Class: [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) + +- [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) SubClassOf [transferase activity](http://purl.obolibrary.org/obo/GO_0016740) + + +### adipose dendritic cell `http://purl.obolibrary.org/obo/CL_0002462` +#### Removed +- [adipose dendritic cell](http://purl.obolibrary.org/obo/CL_0002462) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [adipose tissue](http://purl.obolibrary.org/obo/UBERON_0001013)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) + +- [adipose dendritic cell](http://purl.obolibrary.org/obo/CL_0002462) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813) + +#### Added +- [adipose dendritic cell](http://purl.obolibrary.org/obo/CL_0002462) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [adipose tissue](http://purl.obolibrary.org/obo/UBERON_0001013)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) + +- [adipose dendritic cell](http://purl.obolibrary.org/obo/CL_0002462) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813) + + +### adjacent to `http://purl.obolibrary.org/obo/RO_0002220` +#### Removed +- [adjacent to](http://purl.obolibrary.org/obo/RO_0002220) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [adjacent to](http://purl.obolibrary.org/obo/RO_0002220) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### adjuvant `http://purl.obolibrary.org/obo/CHEBI_60809` +#### Removed +- [adjuvant](http://purl.obolibrary.org/obo/CHEBI_60809) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "adjuvants" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [adjuvant](http://purl.obolibrary.org/obo/CHEBI_60809) [label](http://www.w3.org/2000/01/rdf-schema#label) "adjuvant" + +- [adjuvant](http://purl.obolibrary.org/obo/CHEBI_60809) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [adjuvant](http://purl.obolibrary.org/obo/CHEBI_60809) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself." + +- [adjuvant](http://purl.obolibrary.org/obo/CHEBI_60809) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [adjuvant](http://purl.obolibrary.org/obo/CHEBI_60809) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:60809" + +- Class: [adjuvant](http://purl.obolibrary.org/obo/CHEBI_60809) + +- [adjuvant](http://purl.obolibrary.org/obo/CHEBI_60809) SubClassOf [pharmaceutical](http://purl.obolibrary.org/obo/CHEBI_52217) + + + +### adrenal medulla chromaffin cell `http://purl.obolibrary.org/obo/CL_0000336` +#### Removed +- [adrenal medulla chromaffin cell](http://purl.obolibrary.org/obo/CL_0000336) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000422" + + + +### adrenaline `http://purl.obolibrary.org/obo/CHEBI_33568` +#### Removed +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "racepinefrinum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A catecholamine in which the aminoethyl side-chain is hydroxy-substituted at C-1 and methylated on nitrogen." + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10052027" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24252294" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:2212160" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dl-adrenaline" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "UCTWMZQNUQWSLP-UHFFFAOYSA-N" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:51559" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:329-65-7" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(+-)-adrenaline" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPHAR" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "2-(methylamino)-1-(3,4-dihydroxyphenyl)ethanol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33568" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(+-)-epinephrine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "racepinefrina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [mass](http://purl.obolibrary.org/obo/chebi/mass) "183.20446" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C9H13NO3" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:2212160" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "epinephrine racemic" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "183.08954" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "racepinefrine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24719616" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "CNCC(O)c1ccc(O)c(O)c1" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [label](http://www.w3.org/2000/01/rdf-schema#label) "adrenaline" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LINCS:LSM-4958" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:4508" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568) SubClassOf [catecholamine](http://purl.obolibrary.org/obo/CHEBI_33567) + + + +### adrenergic agent `http://purl.obolibrary.org/obo/CHEBI_37962` +#### Removed +- [adrenergic agent](http://purl.obolibrary.org/obo/CHEBI_37962) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [adrenergic agent](http://purl.obolibrary.org/obo/CHEBI_37962) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "adrenergic drug" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [adrenergic agent](http://purl.obolibrary.org/obo/CHEBI_37962) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "adrenergics" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [adrenergic agent](http://purl.obolibrary.org/obo/CHEBI_37962) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "adrenergic drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [adrenergic agent](http://purl.obolibrary.org/obo/CHEBI_37962) [label](http://www.w3.org/2000/01/rdf-schema#label) "adrenergic agent" + +- [adrenergic agent](http://purl.obolibrary.org/obo/CHEBI_37962) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter." + +- [adrenergic agent](http://purl.obolibrary.org/obo/CHEBI_37962) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:37962" + +- [adrenergic agent](http://purl.obolibrary.org/obo/CHEBI_37962) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [adrenergic agent](http://purl.obolibrary.org/obo/CHEBI_37962) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "adrenergic agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [adrenergic agent](http://purl.obolibrary.org/obo/CHEBI_37962) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "adrenergic neuron agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [adrenergic agent](http://purl.obolibrary.org/obo/CHEBI_37962) + +- [adrenergic agent](http://purl.obolibrary.org/obo/CHEBI_37962) SubClassOf [neurotransmitter agent](http://purl.obolibrary.org/obo/CHEBI_35942) + + + +### adrenergic agonist `http://purl.obolibrary.org/obo/CHEBI_37886` +#### Removed +- [adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_37886) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "adrenomimetic" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_37886) [label](http://www.w3.org/2000/01/rdf-schema#label) "adrenergic agonist" + +- [adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_37886) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:37886" + +- [adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_37886) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_37886) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "adrenergic agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_37886) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "adrenoceptor agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPHAR" + +- [adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_37886) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "adrenomimetics" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_37886) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An agent that selectively binds to and activates adrenergic receptors." + +- [adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_37886) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "adrenergic receptor agonist" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_37886) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_37886) + +- [adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_37886) SubClassOf [adrenergic agent](http://purl.obolibrary.org/obo/CHEBI_37962) + + + +### adrenocorticotropic hormone secreting cell `http://purl.obolibrary.org/obo/CL_0000467` +#### Removed +- [adrenocorticotropic hormone secreting cell](http://purl.obolibrary.org/obo/CL_0000467) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000640" + +- [adrenocorticotropic hormone secreting cell](http://purl.obolibrary.org/obo/CL_0000467) SubClassOf [endocrine cell](http://purl.obolibrary.org/obo/CL_0000163) + + + +### aetiopathogenetic role `http://purl.obolibrary.org/obo/CHEBI_52209` +#### Removed +- [aetiopathogenetic role](http://purl.obolibrary.org/obo/CHEBI_52209) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [aetiopathogenetic role](http://purl.obolibrary.org/obo/CHEBI_52209) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:52209" + +- [aetiopathogenetic role](http://purl.obolibrary.org/obo/CHEBI_52209) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A role played by the molecular entity or part thereof which causes the development of a pathological process." + +- [aetiopathogenetic role](http://purl.obolibrary.org/obo/CHEBI_52209) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [aetiopathogenetic role](http://purl.obolibrary.org/obo/CHEBI_52209) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "etiopathogenetic role" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [aetiopathogenetic role](http://purl.obolibrary.org/obo/CHEBI_52209) [label](http://www.w3.org/2000/01/rdf-schema#label) "aetiopathogenetic role" + +- [aetiopathogenetic role](http://purl.obolibrary.org/obo/CHEBI_52209) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "etiopathogenetic agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [aetiopathogenetic role](http://purl.obolibrary.org/obo/CHEBI_52209) + +- [aetiopathogenetic role](http://purl.obolibrary.org/obo/CHEBI_52209) SubClassOf [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) + + + +### agonist `http://purl.obolibrary.org/obo/CHEBI_48705` +#### Removed +- [agonist](http://purl.obolibrary.org/obo/CHEBI_48705) [label](http://www.w3.org/2000/01/rdf-schema#label) "agonist" + +- [agonist](http://purl.obolibrary.org/obo/CHEBI_48705) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [agonist](http://purl.obolibrary.org/obo/CHEBI_48705) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:48705" + +- [agonist](http://purl.obolibrary.org/obo/CHEBI_48705) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "agonista" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [agonist](http://purl.obolibrary.org/obo/CHEBI_48705) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own." + +- [agonist](http://purl.obolibrary.org/obo/CHEBI_48705) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "agoniste" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [agonist](http://purl.obolibrary.org/obo/CHEBI_48705) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "agonist" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [agonist](http://purl.obolibrary.org/obo/CHEBI_48705) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [agonist](http://purl.obolibrary.org/obo/CHEBI_48705) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [agonist](http://purl.obolibrary.org/obo/CHEBI_48705) + +- [agonist](http://purl.obolibrary.org/obo/CHEBI_48705) SubClassOf [pharmacological role](http://purl.obolibrary.org/obo/CHEBI_52210) + + + +### agrochemical `http://purl.obolibrary.org/obo/CHEBI_33286` +#### Removed +- [agrochemical](http://purl.obolibrary.org/obo/CHEBI_33286) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "agricultural chemicals" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [agrochemical](http://purl.obolibrary.org/obo/CHEBI_33286) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An agrochemical is a substance that is used in agriculture or horticulture." + +- [agrochemical](http://purl.obolibrary.org/obo/CHEBI_33286) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33286" + +- [agrochemical](http://purl.obolibrary.org/obo/CHEBI_33286) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [agrochemical](http://purl.obolibrary.org/obo/CHEBI_33286) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "agrichemical" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [agrochemical](http://purl.obolibrary.org/obo/CHEBI_33286) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [agrochemical](http://purl.obolibrary.org/obo/CHEBI_33286) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Agrochemical" + +- [agrochemical](http://purl.obolibrary.org/obo/CHEBI_33286) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "agrichemicals" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [agrochemical](http://purl.obolibrary.org/obo/CHEBI_33286) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "agrochemicals" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [agrochemical](http://purl.obolibrary.org/obo/CHEBI_33286) [label](http://www.w3.org/2000/01/rdf-schema#label) "agrochemical" + +- Class: [agrochemical](http://purl.obolibrary.org/obo/CHEBI_33286) + +- [agrochemical](http://purl.obolibrary.org/obo/CHEBI_33286) SubClassOf [application](http://purl.obolibrary.org/obo/CHEBI_33232) + + + +### airway submucosal gland `http://purl.obolibrary.org/obo/UBERON_8410077` +#### Removed +- [airway submucosal gland](http://purl.obolibrary.org/obo/UBERON_8410077) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-2825-0621](http://orcid.org/0000-0002-2825-0621) + +#### Added +- [airway submucosal gland](http://purl.obolibrary.org/obo/UBERON_8410077) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-2825-0621](https://orcid.org/0000-0002-2825-0621) + + +### airway submucosal gland collecting duct epithelial cell `http://purl.obolibrary.org/obo/CL_4033023` + +#### Added +- [airway submucosal gland collecting duct epithelial cell](http://purl.obolibrary.org/obo/CL_4033023) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- [airway submucosal gland collecting duct epithelial cell](http://purl.obolibrary.org/obo/CL_4033023) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-9185-3994](https://orcid.org/0000-0002-9185-3994) + +- [airway submucosal gland collecting duct epithelial cell](http://purl.obolibrary.org/obo/CL_4033023) [label](http://www.w3.org/2000/01/rdf-schema#label) "airway submucosal gland collecting duct epithelial cell" + +- [airway submucosal gland collecting duct epithelial cell](http://purl.obolibrary.org/obo/CL_4033023) [date](http://purl.org/dc/terms/date) "2023-03-16T15:20:28Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [airway submucosal gland collecting duct epithelial cell](http://purl.obolibrary.org/obo/CL_4033023) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An epithelial cell that is part of a collecting duct of an airway submucosal gland." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:29656943" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25648514" + +- Class: [airway submucosal gland collecting duct epithelial cell](http://purl.obolibrary.org/obo/CL_4033023) + +- [airway submucosal gland collecting duct epithelial cell](http://purl.obolibrary.org/obo/CL_4033023) SubClassOf [epithelial cell](http://purl.obolibrary.org/obo/CL_0000066) + +- [airway submucosal gland collecting duct epithelial cell](http://purl.obolibrary.org/obo/CL_4033023) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [airway submucosal gland](http://purl.obolibrary.org/obo/UBERON_8410077) + + +### airway submucosal gland duct basal cell `http://purl.obolibrary.org/obo/CL_4033024` + +#### Added +- [airway submucosal gland duct basal cell](http://purl.obolibrary.org/obo/CL_4033024) [label](http://www.w3.org/2000/01/rdf-schema#label) "airway submucosal gland duct basal cell" + +- [airway submucosal gland duct basal cell](http://purl.obolibrary.org/obo/CL_4033024) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A basal cell that is part of a duct of an airway submucosal gland." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:35046051" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:29656943" + +- [airway submucosal gland duct basal cell](http://purl.obolibrary.org/obo/CL_4033024) [date](http://purl.org/dc/terms/date) "2023-03-16T15:51:39Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [airway submucosal gland duct basal cell](http://purl.obolibrary.org/obo/CL_4033024) [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0002-9185-3994" + +- [airway submucosal gland duct basal cell](http://purl.obolibrary.org/obo/CL_4033024) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- Class: [airway submucosal gland duct basal cell](http://purl.obolibrary.org/obo/CL_4033024) + +- [airway submucosal gland duct basal cell](http://purl.obolibrary.org/obo/CL_4033024) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [airway submucosal gland](http://purl.obolibrary.org/obo/UBERON_8410077) + +- [airway submucosal gland duct basal cell](http://purl.obolibrary.org/obo/CL_4033024) SubClassOf [basal cell](http://purl.obolibrary.org/obo/CL_0000646) + + +### alcohol `http://purl.obolibrary.org/obo/CHEBI_30879` +#### Removed +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:30879" + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:2553" + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CHOR3" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [FORMULA](http://purl.obolibrary.org/obo/fbbt#FORMULA) + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [formula](http://purl.obolibrary.org/obo/chebi/formula) "HOR" + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HOR" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [FORMULA](http://purl.obolibrary.org/obo/fbbt#FORMULA) + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00069" + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13804" + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "O[*]" + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22288" + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alcohols" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [mass](http://purl.obolibrary.org/obo/chebi/mass) "17.007" + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "an alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [label](http://www.w3.org/2000/01/rdf-schema#label) "alcohol" + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "17.00274" + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "OC([*])([*])[*]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [SMILES](http://purl.obolibrary.org/obo/fbbt#SMILES) + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alcohols" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) + +- [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) SubClassOf [organic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_33822) + + + +### alcohol binding `http://purl.obolibrary.org/obo/GO_0043178` +#### Removed +- [alcohol binding](http://purl.obolibrary.org/obo/GO_0043178) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to an alcohol, any of a class of alkyl compounds containing a hydroxyl group." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [alcohol binding](http://purl.obolibrary.org/obo/GO_0043178) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0043178" + +- [alcohol binding](http://purl.obolibrary.org/obo/GO_0043178) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [alcohol binding](http://purl.obolibrary.org/obo/GO_0043178) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_pir](http://purl.obolibrary.org/obo/go#goslim_pir) + +- [alcohol binding](http://purl.obolibrary.org/obo/GO_0043178) [label](http://www.w3.org/2000/01/rdf-schema#label) "alcohol binding" + +- Class: [alcohol binding](http://purl.obolibrary.org/obo/GO_0043178) + +- [alcohol binding](http://purl.obolibrary.org/obo/GO_0043178) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879)) + +- [alcohol binding](http://purl.obolibrary.org/obo/GO_0043178) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) + +- [alcohol binding](http://purl.obolibrary.org/obo/GO_0043178) SubClassOf [small molecule binding](http://purl.obolibrary.org/obo/GO_0036094) + + + +### alcohol biosynthetic process `http://purl.obolibrary.org/obo/GO_0046165` +#### Removed +- [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alcohol biosynthesis" + +- [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alcohol anabolism" + +- [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046165" + +- [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alcohol formation" + +- [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) [label](http://www.w3.org/2000/01/rdf-schema#label) "alcohol biosynthetic process" + +- [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alcohol synthesis" + +- Class: [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) + +- [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879)) + +- [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) + +- [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) SubClassOf [organic hydroxy compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901617) + +- [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) SubClassOf [alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0006066) + +- [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) SubClassOf [small molecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0044283) + + + +### alcohol catabolic process `http://purl.obolibrary.org/obo/GO_0046164` +#### Removed +- [alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0046164) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046164" + +- [alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0046164) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0046164) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alcohol breakdown" + +- [alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0046164) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alcohol degradation" + +- [alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0046164) [label](http://www.w3.org/2000/01/rdf-schema#label) "alcohol catabolic process" + +- [alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0046164) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alcohol catabolism" + +- [alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0046164) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- Class: [alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0046164) + +- [alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0046164) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879)) + +- [alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0046164) SubClassOf [small molecule catabolic process](http://purl.obolibrary.org/obo/GO_0044282) + +- [alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0046164) SubClassOf [organic hydroxy compound catabolic process](http://purl.obolibrary.org/obo/GO_1901616) + +- [alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0046164) SubClassOf [alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0006066) + +- [alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0046164) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) + + + +### alcohol metabolic process `http://purl.obolibrary.org/obo/GO_0006066` +#### Removed +- [alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0006066) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alcohol metabolism" + +- [alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0006066) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0006066) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_drosophila](http://purl.obolibrary.org/obo/go#goslim_drosophila) + +- [alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0006066) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006066" + +- [alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0006066) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_pir](http://purl.obolibrary.org/obo/go#goslim_pir) + +- [alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0006066) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0006066) [label](http://www.w3.org/2000/01/rdf-schema#label) "alcohol metabolic process" + +- Class: [alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0006066) + +- [alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0006066) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879)) + +- [alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0006066) SubClassOf [organic hydroxy compound metabolic process](http://purl.obolibrary.org/obo/GO_1901615) + +- [alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0006066) SubClassOf [small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0044281) + +- [alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0006066) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) + + + +### alcohol transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015665` +#### Removed +- [alcohol transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015665) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015665" + +- [alcohol transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015665) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of an alcohol from one side of a membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [alcohol transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015665) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [alcohol transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015665) [label](http://www.w3.org/2000/01/rdf-schema#label) "alcohol transmembrane transporter activity" + +- Class: [alcohol transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015665) + +- [alcohol transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015665) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879)) + +- [alcohol transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015665) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) + +- [alcohol transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015665) SubClassOf [organic hydroxy compound transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901618) + + + +### aldehyde `http://purl.obolibrary.org/obo/CHEBI_17478` +#### Removed +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aldehyde" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aldehydes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "RC(=O)H" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H]C([*])=O" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aldehidos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aldehydes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Aldehyd" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aldehido" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "29.00274" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:8750" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22291" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [mass](http://purl.obolibrary.org/obo/chebi/mass) "29.01800" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13806" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13805" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "an aldehyde" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aldehyde" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aldehydum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CHOR" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [label](http://www.w3.org/2000/01/rdf-schema#label) "aldehyde" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00071" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13432" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:17478" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Aldehyde" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group." + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "RCHO" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13753" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:2554" + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) SubClassOf [carbonyl compound](http://purl.obolibrary.org/obo/CHEBI_36586) + +- [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) + + + +### aldehyde catabolic process `http://purl.obolibrary.org/obo/GO_0046185` +#### Removed +- [aldehyde catabolic process](http://purl.obolibrary.org/obo/GO_0046185) SubClassOf [organic substance catabolic process](http://purl.obolibrary.org/obo/GO_1901575) + + + +### aldohexose `http://purl.obolibrary.org/obo/CHEBI_33917` +#### Removed +- [aldohexose](http://purl.obolibrary.org/obo/CHEBI_33917) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aldohexose" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [aldohexose](http://purl.obolibrary.org/obo/CHEBI_33917) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33917" + +- [aldohexose](http://purl.obolibrary.org/obo/CHEBI_33917) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aldohexoses" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [aldohexose](http://purl.obolibrary.org/obo/CHEBI_33917) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:2558" + +- [aldohexose](http://purl.obolibrary.org/obo/CHEBI_33917) [label](http://www.w3.org/2000/01/rdf-schema#label) "aldohexose" + +- [aldohexose](http://purl.obolibrary.org/obo/CHEBI_33917) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A hexose with a (potential) aldehyde group at one end." + +- [aldohexose](http://purl.obolibrary.org/obo/CHEBI_33917) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [aldohexose](http://purl.obolibrary.org/obo/CHEBI_33917) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [aldohexose](http://purl.obolibrary.org/obo/CHEBI_33917) + +- [aldohexose](http://purl.obolibrary.org/obo/CHEBI_33917) SubClassOf [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) + +- [aldohexose](http://purl.obolibrary.org/obo/CHEBI_33917) SubClassOf [hexose](http://purl.obolibrary.org/obo/CHEBI_18133) + + + +### aldose `http://purl.obolibrary.org/obo/CHEBI_15693` +#### Removed +- [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:2561" + +- [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Aldose" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01370" + +- [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:15693" + +- [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22305" + +- [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aldoses" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "an aldose" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Aldose" + +- [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13755" + +- [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals." + +- [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) [label](http://www.w3.org/2000/01/rdf-schema#label) "aldose" + +- [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2H4O2(CH2O)n" + +- Class: [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) + +- [aldose](http://purl.obolibrary.org/obo/CHEBI_15693) SubClassOf [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) + + + +### aldosterone `http://purl.obolibrary.org/obo/CHEBI_27584` +#### Removed +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LINCS:LSM-42770" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aldosterone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [mass](http://purl.obolibrary.org/obo/chebi/mass) "360.44400" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ALDOSTERONE" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(11beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:52-39-1" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:40919" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(+)-aldosterone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:27584" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Aldosterone" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "PQSUYGKTWSAVDQ-ZVIOFETBSA-N" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney." + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:2563" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:111" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:3224996" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10438974" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22306" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [label](http://www.w3.org/2000/01/rdf-schema#label) "aldosterone" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01780" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]12C=O)C(=O)CO" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "360.19367" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C21H28O5" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:AS4" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:52-39-1" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB04630" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Aldosterone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LIPID_MAPS_instance:LMST02030026" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "LIPID MAPS" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:3224996" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:52-39-1" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000037" + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) SubClassOf [C21-steroid hormone](http://purl.obolibrary.org/obo/CHEBI_64600) + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) SubClassOf [11beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35346) + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) SubClassOf [21-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35344) + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) SubClassOf [mineralocorticoid](http://purl.obolibrary.org/obo/CHEBI_25354) + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) SubClassOf [has_parent_hydride](http://purl.obolibrary.org/obo/chebi#has_parent_hydride) some [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) SubClassOf [20-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36885) + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) SubClassOf [steroid aldehyde](http://purl.obolibrary.org/obo/CHEBI_131565) + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) SubClassOf [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) SubClassOf [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) + +- [aldosterone](http://purl.obolibrary.org/obo/CHEBI_27584) SubClassOf [18-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36887) + + + +### aldosterone biosynthetic process `http://purl.obolibrary.org/obo/GO_0032342` +#### Removed +- [aldosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_0032342) SubClassOf [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) + +- [aldosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_0032342) SubClassOf [primary alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0034309) + +#### Added +- [aldosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_0032342) SubClassOf [organic hydroxy compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901617) + + +### aldosterone catabolic process `http://purl.obolibrary.org/obo/GO_0032343` +#### Removed +- [aldosterone catabolic process](http://purl.obolibrary.org/obo/GO_0032343) SubClassOf [primary alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0034310) + +- [aldosterone catabolic process](http://purl.obolibrary.org/obo/GO_0032343) SubClassOf [mineralocorticoid catabolic process](http://purl.obolibrary.org/obo/GO_0006712) + +- [aldosterone catabolic process](http://purl.obolibrary.org/obo/GO_0032343) SubClassOf [ketone catabolic process](http://purl.obolibrary.org/obo/GO_0042182) + +- [aldosterone catabolic process](http://purl.obolibrary.org/obo/GO_0032343) SubClassOf [C21-steroid hormone catabolic process](http://purl.obolibrary.org/obo/GO_0008208) + +- [aldosterone catabolic process](http://purl.obolibrary.org/obo/GO_0032343) SubClassOf [aldehyde catabolic process](http://purl.obolibrary.org/obo/GO_0046185) + +- [aldosterone catabolic process](http://purl.obolibrary.org/obo/GO_0032343) SubClassOf [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) + +#### Added +- [aldosterone catabolic process](http://purl.obolibrary.org/obo/GO_0032343) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### aldosterone metabolic process `http://purl.obolibrary.org/obo/GO_0032341` +#### Removed +- [aldosterone metabolic process](http://purl.obolibrary.org/obo/GO_0032341) SubClassOf [primary alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0034308) + +- [aldosterone metabolic process](http://purl.obolibrary.org/obo/GO_0032341) SubClassOf [olefinic compound metabolic process](http://purl.obolibrary.org/obo/GO_0120254) + +#### Added +- [aldosterone metabolic process](http://purl.obolibrary.org/obo/GO_0032341) SubClassOf [organic hydroxy compound metabolic process](http://purl.obolibrary.org/obo/GO_1901615) + + +### algal metabolite `http://purl.obolibrary.org/obo/CHEBI_84735` +#### Removed +- [algal metabolite](http://purl.obolibrary.org/obo/CHEBI_84735) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [algal metabolite](http://purl.obolibrary.org/obo/CHEBI_84735) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:84735" + +- [algal metabolite](http://purl.obolibrary.org/obo/CHEBI_84735) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [algal metabolite](http://purl.obolibrary.org/obo/CHEBI_84735) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae." + +- [algal metabolite](http://purl.obolibrary.org/obo/CHEBI_84735) [label](http://www.w3.org/2000/01/rdf-schema#label) "algal metabolite" + +- [algal metabolite](http://purl.obolibrary.org/obo/CHEBI_84735) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "algal metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [algal metabolite](http://purl.obolibrary.org/obo/CHEBI_84735) + +- [algal metabolite](http://purl.obolibrary.org/obo/CHEBI_84735) SubClassOf [eukaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75763) + + + +### aliphatic compound `http://purl.obolibrary.org/obo/CHEBI_33653` +#### Removed +- [aliphatic compound](http://purl.obolibrary.org/obo/CHEBI_33653) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds." + +- [aliphatic compound](http://purl.obolibrary.org/obo/CHEBI_33653) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [aliphatic compound](http://purl.obolibrary.org/obo/CHEBI_33653) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [aliphatic compound](http://purl.obolibrary.org/obo/CHEBI_33653) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33653" + +- [aliphatic compound](http://purl.obolibrary.org/obo/CHEBI_33653) [label](http://www.w3.org/2000/01/rdf-schema#label) "aliphatic compound" + +- [aliphatic compound](http://purl.obolibrary.org/obo/CHEBI_33653) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aliphatic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- Class: [aliphatic compound](http://purl.obolibrary.org/obo/CHEBI_33653) + +- [aliphatic compound](http://purl.obolibrary.org/obo/CHEBI_33653) SubClassOf [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) + + + +### alkali metal atom `http://purl.obolibrary.org/obo/CHEBI_22314` +#### Removed +- [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkali metals" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metales alcalinos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Alkalimetalle" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metal alcalin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alkali metal" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metaux alcalins" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:22314" + +- [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Alkalimetall" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metal alcalino" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) [label](http://www.w3.org/2000/01/rdf-schema#label) "alkali metal atom" + +- Class: [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) + +- [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) SubClassOf [s-block element atom](http://purl.obolibrary.org/obo/CHEBI_33559) + +- [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) SubClassOf [main group element atom](http://purl.obolibrary.org/obo/CHEBI_33318) + +- [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) SubClassOf [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) + + + +### alkali metal cation `http://purl.obolibrary.org/obo/CHEBI_33504` +#### Removed +- [alkali metal cation](http://purl.obolibrary.org/obo/CHEBI_33504) [label](http://www.w3.org/2000/01/rdf-schema#label) "alkali metal cation" + +- [alkali metal cation](http://purl.obolibrary.org/obo/CHEBI_33504) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alkali metal cation](http://purl.obolibrary.org/obo/CHEBI_33504) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alkali metal cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkali metal cation](http://purl.obolibrary.org/obo/CHEBI_33504) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [alkali metal cation](http://purl.obolibrary.org/obo/CHEBI_33504) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33504" + +- Class: [alkali metal cation](http://purl.obolibrary.org/obo/CHEBI_33504) + +- [alkali metal cation](http://purl.obolibrary.org/obo/CHEBI_33504) SubClassOf [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) + + + +### alkali metal ion binding `http://purl.obolibrary.org/obo/GO_0031420` +#### Removed +- [alkali metal ion binding](http://purl.obolibrary.org/obo/GO_0031420) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0031420" + +- [alkali metal ion binding](http://purl.obolibrary.org/obo/GO_0031420) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to an alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [alkali metal ion binding](http://purl.obolibrary.org/obo/GO_0031420) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [alkali metal ion binding](http://purl.obolibrary.org/obo/GO_0031420) [label](http://www.w3.org/2000/01/rdf-schema#label) "alkali metal ion binding" + +- Class: [alkali metal ion binding](http://purl.obolibrary.org/obo/GO_0031420) + +- [alkali metal ion binding](http://purl.obolibrary.org/obo/GO_0031420) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [alkali metal cation](http://purl.obolibrary.org/obo/CHEBI_33504)) + +- [alkali metal ion binding](http://purl.obolibrary.org/obo/GO_0031420) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [alkali metal cation](http://purl.obolibrary.org/obo/CHEBI_33504) + +- [alkali metal ion binding](http://purl.obolibrary.org/obo/GO_0031420) SubClassOf [metal ion binding](http://purl.obolibrary.org/obo/GO_0046872) + + + +### alkali metal molecular entity `http://purl.obolibrary.org/obo/CHEBI_33296` +#### Removed +- [alkali metal molecular entity](http://purl.obolibrary.org/obo/CHEBI_33296) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecular entity containing one or more atoms of an alkali metal." + +- [alkali metal molecular entity](http://purl.obolibrary.org/obo/CHEBI_33296) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alkali metal molecular entity](http://purl.obolibrary.org/obo/CHEBI_33296) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alkali metal molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkali metal molecular entity](http://purl.obolibrary.org/obo/CHEBI_33296) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [alkali metal molecular entity](http://purl.obolibrary.org/obo/CHEBI_33296) [label](http://www.w3.org/2000/01/rdf-schema#label) "alkali metal molecular entity" + +- [alkali metal molecular entity](http://purl.obolibrary.org/obo/CHEBI_33296) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33296" + +- Class: [alkali metal molecular entity](http://purl.obolibrary.org/obo/CHEBI_33296) + +- [alkali metal molecular entity](http://purl.obolibrary.org/obo/CHEBI_33296) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) + +- [alkali metal molecular entity](http://purl.obolibrary.org/obo/CHEBI_33296) SubClassOf [s-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33674) + + + +### alkali metal salt `http://purl.obolibrary.org/obo/CHEBI_35479` +#### Removed +- [alkali metal salt](http://purl.obolibrary.org/obo/CHEBI_35479) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35479" + +- [alkali metal salt](http://purl.obolibrary.org/obo/CHEBI_35479) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alkali metal salts" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkali metal salt](http://purl.obolibrary.org/obo/CHEBI_35479) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alkali metal salt](http://purl.obolibrary.org/obo/CHEBI_35479) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [alkali metal salt](http://purl.obolibrary.org/obo/CHEBI_35479) [label](http://www.w3.org/2000/01/rdf-schema#label) "alkali metal salt" + +- Class: [alkali metal salt](http://purl.obolibrary.org/obo/CHEBI_35479) + +- [alkali metal salt](http://purl.obolibrary.org/obo/CHEBI_35479) SubClassOf [alkali metal molecular entity](http://purl.obolibrary.org/obo/CHEBI_33296) + +- [alkali metal salt](http://purl.obolibrary.org/obo/CHEBI_35479) SubClassOf [salt](http://purl.obolibrary.org/obo/CHEBI_24866) + + + +### alkaline earth cation `http://purl.obolibrary.org/obo/CHEBI_33513` +#### Removed +- [alkaline earth cation](http://purl.obolibrary.org/obo/CHEBI_33513) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33513" + +- [alkaline earth cation](http://purl.obolibrary.org/obo/CHEBI_33513) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [alkaline earth cation](http://purl.obolibrary.org/obo/CHEBI_33513) [label](http://www.w3.org/2000/01/rdf-schema#label) "alkaline earth cation" + +- [alkaline earth cation](http://purl.obolibrary.org/obo/CHEBI_33513) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alkaline earth metal cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaline earth cation](http://purl.obolibrary.org/obo/CHEBI_33513) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alkaline-earth metal cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaline earth cation](http://purl.obolibrary.org/obo/CHEBI_33513) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alkaline earth cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaline earth cation](http://purl.obolibrary.org/obo/CHEBI_33513) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [alkaline earth cation](http://purl.obolibrary.org/obo/CHEBI_33513) + +- [alkaline earth cation](http://purl.obolibrary.org/obo/CHEBI_33513) SubClassOf [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) + +- [alkaline earth cation](http://purl.obolibrary.org/obo/CHEBI_33513) SubClassOf [alkaline earth molecular entity](http://purl.obolibrary.org/obo/CHEBI_33299) + + + +### alkaline earth metal atom `http://purl.obolibrary.org/obo/CHEBI_22313` +#### Removed +- [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alkaline-earth metal" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Erdalkalimetall" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Erdalkalimetalle" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkaline earth metals" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alkaline earth metal" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:22313" + +- [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alkaline-earth metals" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metal alcalinoterreo" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metaux alcalino-terreux" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metal alcalino-terreux" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metales alcalinoterreos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) [label](http://www.w3.org/2000/01/rdf-schema#label) "alkaline earth metal atom" + +- Class: [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) + +- [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) SubClassOf [s-block element atom](http://purl.obolibrary.org/obo/CHEBI_33559) + +- [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) SubClassOf [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) + +- [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) SubClassOf [main group element atom](http://purl.obolibrary.org/obo/CHEBI_33318) + + + +### alkaline earth molecular entity `http://purl.obolibrary.org/obo/CHEBI_33299` +#### Removed +- [alkaline earth molecular entity](http://purl.obolibrary.org/obo/CHEBI_33299) [label](http://www.w3.org/2000/01/rdf-schema#label) "alkaline earth molecular entity" + +- [alkaline earth molecular entity](http://purl.obolibrary.org/obo/CHEBI_33299) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alkaline-earth compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaline earth molecular entity](http://purl.obolibrary.org/obo/CHEBI_33299) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An alkaline earth molecular entity is a molecular entity containing one or more atoms of an alkaline earth metal." + +- [alkaline earth molecular entity](http://purl.obolibrary.org/obo/CHEBI_33299) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33299" + +- [alkaline earth molecular entity](http://purl.obolibrary.org/obo/CHEBI_33299) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alkaline earth molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaline earth molecular entity](http://purl.obolibrary.org/obo/CHEBI_33299) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alkaline earth compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaline earth molecular entity](http://purl.obolibrary.org/obo/CHEBI_33299) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alkaline earth molecular entity](http://purl.obolibrary.org/obo/CHEBI_33299) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [alkaline earth molecular entity](http://purl.obolibrary.org/obo/CHEBI_33299) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkaline earth molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [alkaline earth molecular entity](http://purl.obolibrary.org/obo/CHEBI_33299) + +- [alkaline earth molecular entity](http://purl.obolibrary.org/obo/CHEBI_33299) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) + +- [alkaline earth molecular entity](http://purl.obolibrary.org/obo/CHEBI_33299) SubClassOf [s-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33674) + + + +### alkaloid `http://purl.obolibrary.org/obo/CHEBI_22315` +#### Removed +- [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Alkaloide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Alkaloid" + +- [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alcaloides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:22315" + +- [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Alkaloid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alcaloide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) [label](http://www.w3.org/2000/01/rdf-schema#label) "alkaloid" + +- [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkaloids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids." + +- Class: [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) + +- [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) + +- [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) SubClassOf [organonitrogen compound](http://purl.obolibrary.org/obo/CHEBI_35352) + + + +### alkaloid biosynthetic process `http://purl.obolibrary.org/obo/GO_0009821` +#### Removed +- [alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009821) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UM-BBD_enzymeID:e0711" + +- [alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009821) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:lr" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0122146743" + +- [alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009821) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkaloid synthesis" + +- [alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009821) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkaloid formation" + +- [alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009821) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0009821" + +- [alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009821) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkaloid biosynthesis" + +- [alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009821) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009821) [label](http://www.w3.org/2000/01/rdf-schema#label) "alkaloid biosynthetic process" + +- [alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009821) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkaloid anabolism" + +- Class: [alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009821) + +- [alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009821) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315)) + +- [alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009821) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) + +- [alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009821) SubClassOf [organonitrogen compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901566) + +- [alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009821) SubClassOf [alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0009820) + +- [alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009821) SubClassOf [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550) + + + +### alkaloid catabolic process `http://purl.obolibrary.org/obo/GO_0009822` +#### Removed +- [alkaloid catabolic process](http://purl.obolibrary.org/obo/GO_0009822) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:lr" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0122146743" + +- [alkaloid catabolic process](http://purl.obolibrary.org/obo/GO_0009822) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkaloid breakdown" + +- [alkaloid catabolic process](http://purl.obolibrary.org/obo/GO_0009822) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [alkaloid catabolic process](http://purl.obolibrary.org/obo/GO_0009822) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkaloid catabolism" + +- [alkaloid catabolic process](http://purl.obolibrary.org/obo/GO_0009822) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0009822" + +- [alkaloid catabolic process](http://purl.obolibrary.org/obo/GO_0009822) [label](http://www.w3.org/2000/01/rdf-schema#label) "alkaloid catabolic process" + +- [alkaloid catabolic process](http://purl.obolibrary.org/obo/GO_0009822) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkaloid degradation" + +- Class: [alkaloid catabolic process](http://purl.obolibrary.org/obo/GO_0009822) + +- [alkaloid catabolic process](http://purl.obolibrary.org/obo/GO_0009822) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315)) + +- [alkaloid catabolic process](http://purl.obolibrary.org/obo/GO_0009822) SubClassOf [alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0009820) + +- [alkaloid catabolic process](http://purl.obolibrary.org/obo/GO_0009822) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) + +- [alkaloid catabolic process](http://purl.obolibrary.org/obo/GO_0009822) SubClassOf [cellular nitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_0044270) + +- [alkaloid catabolic process](http://purl.obolibrary.org/obo/GO_0009822) SubClassOf [organonitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_1901565) + + + +### alkaloid metabolic process `http://purl.obolibrary.org/obo/GO_0009820` +#### Removed +- [alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0009820) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_chembl](http://purl.obolibrary.org/obo/go#goslim_chembl) + +- [alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0009820) [label](http://www.w3.org/2000/01/rdf-schema#label) "alkaloid metabolic process" + +- [alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0009820) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0009820" + +- [alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0009820) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:lr" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0122146743" + +- [alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0009820) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0009820) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkaloid metabolism" + +- Class: [alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0009820) + +- [alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0009820) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315)) + +- [alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0009820) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) + +- [alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0009820) SubClassOf [organonitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_1901564) + + + +### alkane `http://purl.obolibrary.org/obo/CHEBI_18310` +#### Removed +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01371" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alcanos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alcane" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13435" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "an alkane" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alcano" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [mass](http://purl.obolibrary.org/obo/chebi/mass) "15.035" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CH3R" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:18310" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms." + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "RH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkane" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [label](http://www.w3.org/2000/01/rdf-schema#label) "alkane" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alcanes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "15.02348" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkanes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Alkane" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:2576" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C[*]" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22317" + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Alkan" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) SubClassOf [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) + +- [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) SubClassOf [aliphatic compound](http://purl.obolibrary.org/obo/CHEBI_33653) + + + +### alkane biosynthetic process `http://purl.obolibrary.org/obo/GO_0043447` +#### Removed +- [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkane anabolism" + +- [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkane formation" + +- [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0043447" + +- [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkane synthesis" + +- [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Alkane" + +- [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkane biosynthesis" + +- [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447) [label](http://www.w3.org/2000/01/rdf-schema#label) "alkane biosynthetic process" + +- Class: [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447) + +- [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [alkane](http://purl.obolibrary.org/obo/CHEBI_18310)) + +- [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447) SubClassOf [cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0044249) + +- [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) + +- [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447) SubClassOf [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) + +- [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447) SubClassOf [cellular alkane metabolic process](http://purl.obolibrary.org/obo/GO_0043446) + + + +### alkane catabolic process `http://purl.obolibrary.org/obo/GO_0043448` +#### Removed +- [alkane catabolic process](http://purl.obolibrary.org/obo/GO_0043448) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [alkane catabolic process](http://purl.obolibrary.org/obo/GO_0043448) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkane breakdown" + +- [alkane catabolic process](http://purl.obolibrary.org/obo/GO_0043448) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0043448" + +- [alkane catabolic process](http://purl.obolibrary.org/obo/GO_0043448) [label](http://www.w3.org/2000/01/rdf-schema#label) "alkane catabolic process" + +- [alkane catabolic process](http://purl.obolibrary.org/obo/GO_0043448) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Alkane" + +- [alkane catabolic process](http://purl.obolibrary.org/obo/GO_0043448) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkane degradation" + +- [alkane catabolic process](http://purl.obolibrary.org/obo/GO_0043448) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkane catabolism" + +- Class: [alkane catabolic process](http://purl.obolibrary.org/obo/GO_0043448) + +- [alkane catabolic process](http://purl.obolibrary.org/obo/GO_0043448) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [alkane](http://purl.obolibrary.org/obo/CHEBI_18310)) + +- [alkane catabolic process](http://purl.obolibrary.org/obo/GO_0043448) SubClassOf [cellular catabolic process](http://purl.obolibrary.org/obo/GO_0044248) + +- [alkane catabolic process](http://purl.obolibrary.org/obo/GO_0043448) SubClassOf [cellular alkane metabolic process](http://purl.obolibrary.org/obo/GO_0043446) + +- [alkane catabolic process](http://purl.obolibrary.org/obo/GO_0043448) SubClassOf [hydrocarbon catabolic process](http://purl.obolibrary.org/obo/GO_0120253) + +- [alkane catabolic process](http://purl.obolibrary.org/obo/GO_0043448) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) + + + +### alkane transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015567` +#### Removed +- [alkane transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015567) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [alkane transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015567) [label](http://www.w3.org/2000/01/rdf-schema#label) "alkane transmembrane transporter activity" + +- [alkane transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015567) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of alkanes from one side of a membrane to the other. Alkanes are saturated aliphatic hydrocarbon compounds." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [alkane transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015567) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015567" + +- Class: [alkane transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015567) + +- [alkane transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015567) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [alkane](http://purl.obolibrary.org/obo/CHEBI_18310)) + +- [alkane transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015567) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + +- [alkane transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015567) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) + +- [alkane transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015567) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [alkane transport](http://purl.obolibrary.org/obo/GO_0015895) + - [source](http://www.geneontology.org/formats/oboInOwl#http://purl.org/dc/terms/source) "GO_REF:0000090" + + + +### alkane transport `http://purl.obolibrary.org/obo/GO_0015895` +#### Removed +- [alkane transport](http://purl.obolibrary.org/obo/GO_0015895) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of alkanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanes are saturated aliphatic hydrocarbon compounds." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [alkane transport](http://purl.obolibrary.org/obo/GO_0015895) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [alkane transport](http://purl.obolibrary.org/obo/GO_0015895) [label](http://www.w3.org/2000/01/rdf-schema#label) "alkane transport" + +- [alkane transport](http://purl.obolibrary.org/obo/GO_0015895) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015895" + +- Class: [alkane transport](http://purl.obolibrary.org/obo/GO_0015895) + +- [alkane transport](http://purl.obolibrary.org/obo/GO_0015895) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [alkane](http://purl.obolibrary.org/obo/CHEBI_18310)) + +- [alkane transport](http://purl.obolibrary.org/obo/GO_0015895) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) + +- [alkane transport](http://purl.obolibrary.org/obo/GO_0015895) SubClassOf [organic substance transport](http://purl.obolibrary.org/obo/GO_0071702) + + + +### alpha,beta-unsaturated ketone `http://purl.obolibrary.org/obo/CHEBI_51721` +#### Removed +- [alpha,beta-unsaturated ketone](http://purl.obolibrary.org/obo/CHEBI_51721) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) or R(1)C#C-C(=O)R(2) (R(2) =/= H) in which the ketonic C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position." + +- [alpha,beta-unsaturated ketone](http://purl.obolibrary.org/obo/CHEBI_51721) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha,beta-unsaturated ketones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alpha,beta-unsaturated ketone](http://purl.obolibrary.org/obo/CHEBI_51721) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alpha,beta-unsaturated ketone](http://purl.obolibrary.org/obo/CHEBI_51721) [label](http://www.w3.org/2000/01/rdf-schema#label) "alpha,beta-unsaturated ketone" + +- [alpha,beta-unsaturated ketone](http://purl.obolibrary.org/obo/CHEBI_51721) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:51721" + +- [alpha,beta-unsaturated ketone](http://purl.obolibrary.org/obo/CHEBI_51721) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [alpha,beta-unsaturated ketone](http://purl.obolibrary.org/obo/CHEBI_51721) + +- [alpha,beta-unsaturated ketone](http://purl.obolibrary.org/obo/CHEBI_51721) SubClassOf [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) + + + +### alpha-adrenergic agonist `http://purl.obolibrary.org/obo/CHEBI_35569` +#### Removed +- [alpha-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35569) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [alpha-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35569) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alpha-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35569) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35569" + +- [alpha-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35569) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-adrenergic agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alpha-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35569) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-adrenoceptor agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPHAR" + +- [alpha-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35569) [label](http://www.w3.org/2000/01/rdf-schema#label) "alpha-adrenergic agonist" + +- [alpha-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35569) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An agent that selectively binds to and activates alpha-adrenergic receptors." + +- [alpha-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35569) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-adrenergic receptor agonist" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [alpha-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35569) + +- [alpha-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35569) SubClassOf [adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_37886) + +- [alpha-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35569) SubClassOf [alpha-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48539) + + + +### alpha-adrenergic drug `http://purl.obolibrary.org/obo/CHEBI_48539` +#### Removed +- [alpha-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48539) [label](http://www.w3.org/2000/01/rdf-schema#label) "alpha-adrenergic drug" + +- [alpha-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48539) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [alpha-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48539) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any drug that acts on an alpha-adrenergic receptor." + +- [alpha-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48539) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-adrenergic drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alpha-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48539) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alpha-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48539) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:48539" + +- Class: [alpha-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48539) + +- [alpha-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48539) SubClassOf [adrenergic agent](http://purl.obolibrary.org/obo/CHEBI_37962) + + + +### alpha-amino acid `http://purl.obolibrary.org/obo/CHEBI_33704` +#### Removed +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "JCBN" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [mass](http://purl.obolibrary.org/obo/chebi/mass) "74.05870" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alpha-amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:2642" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:10208" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [label](http://www.w3.org/2000/01/rdf-schema#label) "alpha-amino acid" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C05167" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33704" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alpha-amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-amino carboxylic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group." + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "an alpha-amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt:" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "74.02420" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00045" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-amino carboxylic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "NC([*])C(O)=O" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22442" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "JCBN:" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2H4NO2R" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13779" + +- Class: [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [alpha-amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_33558) + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) SubClassOf [is_tautomer_of](http://purl.obolibrary.org/obo/chebi#is_tautomer_of) some [alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_78608) + +- [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) SubClassOf [amino acid](http://purl.obolibrary.org/obo/CHEBI_33709) + + + +### alpha-amino acid catabolic process `http://purl.obolibrary.org/obo/GO_1901606` +#### Removed +- [alpha-amino acid catabolic process](http://purl.obolibrary.org/obo/GO_1901606) SubClassOf [organic substance catabolic process](http://purl.obolibrary.org/obo/GO_1901575) + +#### Added +- [alpha-amino acid catabolic process](http://purl.obolibrary.org/obo/GO_1901606) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### alpha-amino acid zwitterion `http://purl.obolibrary.org/obo/CHEBI_78608` +#### Removed +- [alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_78608) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_78608) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "74.02420" + +- [alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_78608) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2H4NO2R" + +- [alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_78608) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:Alpha-Amino-Acids" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "SUBMITTER" + +- [alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_78608) [mass](http://purl.obolibrary.org/obo/chebi/mass) "74.059" + +- [alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_78608) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_78608) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3." + +- [alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_78608) [label](http://www.w3.org/2000/01/rdf-schema#label) "alpha-amino acid zwitterion" + +- [alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_78608) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_78608) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[NH3+]C([*])C([O-])=O" + +- [alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_78608) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:78608" + +- [alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_78608) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:83409" + +- [alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_78608) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "an alpha-amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_78608) SubClassOf [is_tautomer_of](http://purl.obolibrary.org/obo/chebi#is_tautomer_of) some [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) + +- [alpha-amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_78608) SubClassOf [amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_35238) + + + +### alpha-amino-acid anion `http://purl.obolibrary.org/obo/CHEBI_33558` +#### Removed +- [alpha-amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_33558) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33558" + +- [alpha-amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_33558) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-amino-acid anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alpha-amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_33558) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alpha-amino-acid anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alpha-amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_33558) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [alpha-amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_33558) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-amino acid anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alpha-amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_33558) [label](http://www.w3.org/2000/01/rdf-schema#label) "alpha-amino-acid anion" + +- [alpha-amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_33558) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alpha-amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_33558) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An amino-acid anion obtained by deprotonation of any alpha-amino acid." + +- Class: [alpha-amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_33558) + +- [alpha-amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_33558) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) + +- [alpha-amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_33558) SubClassOf [amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_37022) + + + +### alpha-amino-acid cation `http://purl.obolibrary.org/obo/CHEBI_33719` +#### Removed +- [alpha-amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33719) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33719" + +- [alpha-amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33719) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-amino acid cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alpha-amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33719) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [alpha-amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33719) [label](http://www.w3.org/2000/01/rdf-schema#label) "alpha-amino-acid cation" + +- [alpha-amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33719) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alpha-amino-acid cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alpha-amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33719) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alpha-amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33719) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-amino-acid cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [alpha-amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33719) + +- [alpha-amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33719) SubClassOf [amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33703) + + + +### alpha-amino-acid residue `http://purl.obolibrary.org/obo/CHEBI_33710` +#### Removed +- [alpha-amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33710) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alpha-amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33710) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [alpha-amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33710) [label](http://www.w3.org/2000/01/rdf-schema#label) "alpha-amino-acid residue" + +- [alpha-amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33710) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-amino-acid residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alpha-amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33710) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33710" + +- Class: [alpha-amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33710) + +- [alpha-amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33710) SubClassOf [amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33708) + +- [alpha-amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33710) SubClassOf [is_substituent_group_from](http://purl.obolibrary.org/obo/chebi#is_substituent_group_from) some [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) + + + +### alpha-hydroxy ketone `http://purl.obolibrary.org/obo/CHEBI_139588` +#### Removed +- [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23295224" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19908854" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-hydroxyketones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-hydroxy ketones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-hydroxy-ketones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) [label](http://www.w3.org/2000/01/rdf-schema#label) "alpha-hydroxy ketone" + +- [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:139588" + +- [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20382022" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15326516" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-hydroxyketone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-hydroxy-ketone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An alpha-oxyketone that has a hydroxy group as the alpha-oxy moiety." + +- Class: [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) + +- [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) SubClassOf [alpha-oxyketone](http://purl.obolibrary.org/obo/CHEBI_52396) + +- [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) SubClassOf [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) + + + +### alpha-oxyketone `http://purl.obolibrary.org/obo/CHEBI_52396` +#### Removed +- [alpha-oxyketone](http://purl.obolibrary.org/obo/CHEBI_52396) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alpha-oxyketones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [alpha-oxyketone](http://purl.obolibrary.org/obo/CHEBI_52396) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [alpha-oxyketone](http://purl.obolibrary.org/obo/CHEBI_52396) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An oxyketone with the general formula R2C(=O) (R=/=H) where one or more of the R groups contains an oxy (-O-) group and the oxy and carbonyl groups are bonded to the same carbon atom." + +- [alpha-oxyketone](http://purl.obolibrary.org/obo/CHEBI_52396) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:52396" + +- [alpha-oxyketone](http://purl.obolibrary.org/obo/CHEBI_52396) [label](http://www.w3.org/2000/01/rdf-schema#label) "alpha-oxyketone" + +- [alpha-oxyketone](http://purl.obolibrary.org/obo/CHEBI_52396) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [alpha-oxyketone](http://purl.obolibrary.org/obo/CHEBI_52396) + +- [alpha-oxyketone](http://purl.obolibrary.org/obo/CHEBI_52396) SubClassOf [oxyketone](http://purl.obolibrary.org/obo/CHEBI_52395) + + + +### alveolar macrophage `http://purl.obolibrary.org/obo/CL_0000583` +#### Removed +- [alveolar macrophage](http://purl.obolibrary.org/obo/CL_0000583) EquivalentTo [tissue-resident macrophage](http://purl.obolibrary.org/obo/CL_0000864) and ([located in](http://purl.obolibrary.org/obo/RO_0001025) some [alveolus of lung](http://purl.obolibrary.org/obo/UBERON_0002299)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-type lectin domain family 7 member A](http://purl.obolibrary.org/obo/PR_000001807)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [sialoadhesin](http://purl.obolibrary.org/obo/PR_000001931)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrosialin](http://purl.obolibrary.org/obo/PR_000002064)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrophage mannose receptor 1](http://purl.obolibrary.org/obo/PR_000002972)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [antigen processing and presentation](http://purl.obolibrary.org/obo/GO_0019882)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206)) + +- [alveolar macrophage](http://purl.obolibrary.org/obo/CL_0000583) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206) + +#### Added +- [alveolar macrophage](http://purl.obolibrary.org/obo/CL_0000583) EquivalentTo [tissue-resident macrophage](http://purl.obolibrary.org/obo/CL_0000864) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206)) and ([located in](http://purl.obolibrary.org/obo/RO_0001025) some [alveolus of lung](http://purl.obolibrary.org/obo/UBERON_0002299)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-type lectin domain family 7 member A](http://purl.obolibrary.org/obo/PR_000001807)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [sialoadhesin](http://purl.obolibrary.org/obo/PR_000001931)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrosialin](http://purl.obolibrary.org/obo/PR_000002064)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrophage mannose receptor 1](http://purl.obolibrary.org/obo/PR_000002972)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [antigen processing and presentation](http://purl.obolibrary.org/obo/GO_0019882)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) + +- [alveolar macrophage](http://purl.obolibrary.org/obo/CL_0000583) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206) + + +### ameloblast `http://purl.obolibrary.org/obo/CL_0000059` +#### Removed +- [ameloblast](http://purl.obolibrary.org/obo/CL_0000059) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000139" + +- [ameloblast](http://purl.obolibrary.org/obo/CL_0000059) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000053" + + + +### amide `http://purl.obolibrary.org/obo/CHEBI_32988` +#### Removed +- [amide](http://purl.obolibrary.org/obo/CHEBI_32988) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22473" + +- [amide](http://purl.obolibrary.org/obo/CHEBI_32988) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:2633" + +- [amide](http://purl.obolibrary.org/obo/CHEBI_32988) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "amides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [amide](http://purl.obolibrary.org/obo/CHEBI_32988) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Amide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [amide](http://purl.obolibrary.org/obo/CHEBI_32988) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00241" + +- [amide](http://purl.obolibrary.org/obo/CHEBI_32988) [label](http://www.w3.org/2000/01/rdf-schema#label) "amide" + +- [amide](http://purl.obolibrary.org/obo/CHEBI_32988) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [amide](http://purl.obolibrary.org/obo/CHEBI_32988) SubClassOf [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) + + + +### amide metabolic process `http://purl.obolibrary.org/obo/GO_0043603` +#### Removed +- [amide metabolic process](http://purl.obolibrary.org/obo/GO_0043603) SubClassOf [nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0006807) + +#### Added +- [amide metabolic process](http://purl.obolibrary.org/obo/GO_0043603) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### amine `http://purl.obolibrary.org/obo/CHEBI_32952` +#### Removed +- [amine](http://purl.obolibrary.org/obo/CHEBI_32952) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [amine](http://purl.obolibrary.org/obo/CHEBI_32952) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:2641" + +- [amine](http://purl.obolibrary.org/obo/CHEBI_32952) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13814" + +- [amine](http://purl.obolibrary.org/obo/CHEBI_32952) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00706" + +- [amine](http://purl.obolibrary.org/obo/CHEBI_32952) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22474" + +- [amine](http://purl.obolibrary.org/obo/CHEBI_32952) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Substituted amine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [amine](http://purl.obolibrary.org/obo/CHEBI_32952) [label](http://www.w3.org/2000/01/rdf-schema#label) "amine" + +- [amine](http://purl.obolibrary.org/obo/CHEBI_32952) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Amine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [amine](http://purl.obolibrary.org/obo/CHEBI_32952) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Amin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [amine](http://purl.obolibrary.org/obo/CHEBI_32952) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "amines" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [amine](http://purl.obolibrary.org/obo/CHEBI_32952) SubClassOf [organic amino compound](http://purl.obolibrary.org/obo/CHEBI_50047) + + + +### amine biosynthetic process `http://purl.obolibrary.org/obo/GO_0009309` +#### Removed +- [amine biosynthetic process](http://purl.obolibrary.org/obo/GO_0009309) SubClassOf [organonitrogen compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901566) + + + +### amine catabolic process `http://purl.obolibrary.org/obo/GO_0009310` +#### Removed +- [amine catabolic process](http://purl.obolibrary.org/obo/GO_0009310) SubClassOf [organonitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_1901565) + +#### Added +- [amine catabolic process](http://purl.obolibrary.org/obo/GO_0009310) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### amine metabolic process `http://purl.obolibrary.org/obo/GO_0009308` +#### Removed +- [amine metabolic process](http://purl.obolibrary.org/obo/GO_0009308) SubClassOf [organonitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_1901564) + +#### Added +- [amine metabolic process](http://purl.obolibrary.org/obo/GO_0009308) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### amine transport `http://purl.obolibrary.org/obo/GO_0015837` +#### Removed +- [amine transport](http://purl.obolibrary.org/obo/GO_0015837) SubClassOf [nitrogen compound transport](http://purl.obolibrary.org/obo/GO_0071705) + +- [amine transport](http://purl.obolibrary.org/obo/GO_0015837) SubClassOf [organic substance transport](http://purl.obolibrary.org/obo/GO_0071702) + +#### Added +- [amine transport](http://purl.obolibrary.org/obo/GO_0015837) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### amino acid `http://purl.obolibrary.org/obo/CHEBI_33709` +#### Removed +- [amino acid](http://purl.obolibrary.org/obo/CHEBI_33709) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Aminokarbonsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [amino acid](http://purl.obolibrary.org/obo/CHEBI_33709) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [amino acid](http://purl.obolibrary.org/obo/CHEBI_33709) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22477" + +- [amino acid](http://purl.obolibrary.org/obo/CHEBI_33709) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13815" + +- [amino acid](http://purl.obolibrary.org/obo/CHEBI_33709) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Amino_acid" + +- [amino acid](http://purl.obolibrary.org/obo/CHEBI_33709) [label](http://www.w3.org/2000/01/rdf-schema#label) "amino acid" + +- [amino acid](http://purl.obolibrary.org/obo/CHEBI_33709) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Aminocarbonsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [amino acid](http://purl.obolibrary.org/obo/CHEBI_33709) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [amino acid](http://purl.obolibrary.org/obo/CHEBI_33709) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Aminosaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [amino acid](http://purl.obolibrary.org/obo/CHEBI_33709) SubClassOf [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) + +- [amino acid](http://purl.obolibrary.org/obo/CHEBI_33709) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_37022) + +- [amino acid](http://purl.obolibrary.org/obo/CHEBI_33709) SubClassOf [organic amino compound](http://purl.obolibrary.org/obo/CHEBI_50047) + + + +### amino acid binding `http://purl.obolibrary.org/obo/GO_0016597` +#### Removed +- [amino acid binding](http://purl.obolibrary.org/obo/GO_0016597) SubClassOf [organic acid binding](http://purl.obolibrary.org/obo/GO_0043177) + +#### Added +- [amino acid binding](http://purl.obolibrary.org/obo/GO_0016597) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### amino acid biosynthetic process `http://purl.obolibrary.org/obo/GO_0008652` +#### Removed +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) SubClassOf [organonitrogen compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901566) + +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) SubClassOf [carboxylic acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046394) + +#### Added +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### amino acid catabolic process `http://purl.obolibrary.org/obo/GO_0009063` +#### Removed +- [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) SubClassOf [carboxylic acid catabolic process](http://purl.obolibrary.org/obo/GO_0046395) + +- [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) SubClassOf [organonitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_1901565) + +#### Added +- [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### amino acid derivative `http://purl.obolibrary.org/obo/CHEBI_83821` +#### Removed +- [amino acid derivative](http://purl.obolibrary.org/obo/CHEBI_83821) [label](http://www.w3.org/2000/01/rdf-schema#label) "amino acid derivative" + +- [amino acid derivative](http://purl.obolibrary.org/obo/CHEBI_83821) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "amino acid derivatives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [amino acid derivative](http://purl.obolibrary.org/obo/CHEBI_83821) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any derivative of an amino acid resulting from reaction at an amino group, carboxy group, side-chain functional group, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing amino acid residues." + +- [amino acid derivative](http://purl.obolibrary.org/obo/CHEBI_83821) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [amino acid derivative](http://purl.obolibrary.org/obo/CHEBI_83821) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:83821" + +- [amino acid derivative](http://purl.obolibrary.org/obo/CHEBI_83821) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "modified amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [amino acid derivative](http://purl.obolibrary.org/obo/CHEBI_83821) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [amino acid derivative](http://purl.obolibrary.org/obo/CHEBI_83821) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:25359" + +- [amino acid derivative](http://purl.obolibrary.org/obo/CHEBI_83821) SubClassOf [organonitrogen compound](http://purl.obolibrary.org/obo/CHEBI_35352) + + + +### amino acid transmembrane transport `http://purl.obolibrary.org/obo/GO_0003333` +#### Removed +- [amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_0003333) SubClassOf [organic acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1903825) + +#### Added +- [amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_0003333) SubClassOf [transmembrane transport](http://purl.obolibrary.org/obo/GO_0055085) + + +### amino acid transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015171` +#### Removed +- [amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015171) SubClassOf [organic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005342) + +#### Added +- [amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015171) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + +### amino acid transport `http://purl.obolibrary.org/obo/GO_0006865` +#### Removed +- [amino acid transport](http://purl.obolibrary.org/obo/GO_0006865) SubClassOf [nitrogen compound transport](http://purl.obolibrary.org/obo/GO_0071705) + +- [amino acid transport](http://purl.obolibrary.org/obo/GO_0006865) SubClassOf [organic acid transport](http://purl.obolibrary.org/obo/GO_0015849) + +#### Added +- [amino acid transport](http://purl.obolibrary.org/obo/GO_0006865) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### amino acid zwitterion `http://purl.obolibrary.org/obo/CHEBI_35238` +#### Removed +- [amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_35238) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_35238) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35238" + +- [amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_35238) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_35238) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group." + +- [amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_35238) [label](http://www.w3.org/2000/01/rdf-schema#label) "amino acid zwitterion" + +- [amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_35238) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "amino acid zwitterion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_35238) + +- [amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_35238) SubClassOf [zwitterion](http://purl.obolibrary.org/obo/CHEBI_27369) + + + +### amino-acid anion `http://purl.obolibrary.org/obo/CHEBI_37022` +#### Removed +- [amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_37022) [label](http://www.w3.org/2000/01/rdf-schema#label) "amino-acid anion" + +- [amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_37022) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "amino acid anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_37022) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "amino-acid anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_37022) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:37022" + +- [amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_37022) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_37022) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_37022) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "amino-acid anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_37022) SubClassOf [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) + +- [amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_37022) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [amino acid](http://purl.obolibrary.org/obo/CHEBI_33709) + +- [amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_37022) SubClassOf [organonitrogen compound](http://purl.obolibrary.org/obo/CHEBI_35352) + + + +### amino-acid cation `http://purl.obolibrary.org/obo/CHEBI_33703` +#### Removed +- [amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33703) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "amino acid cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33703) [label](http://www.w3.org/2000/01/rdf-schema#label) "amino-acid cation" + +- [amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33703) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33703" + +- [amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33703) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "amino-acid cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33703) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "amino-acid cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33703) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33703) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33703) + +- [amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33703) SubClassOf [polyatomic cation](http://purl.obolibrary.org/obo/CHEBI_33702) + + + +### amino-acid residue `http://purl.obolibrary.org/obo/CHEBI_33708` +#### Removed +- [amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33708) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33708) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33708) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue." + +- [amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33708) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "amino-acid residue" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33708) [label](http://www.w3.org/2000/01/rdf-schema#label) "amino-acid residue" + +- [amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33708) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33708" + +- [amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33708) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "amino acid residue" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33708) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "amino-acid residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "JCBN" + +- [amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33708) SubClassOf [organic group](http://purl.obolibrary.org/obo/CHEBI_33247) + +- [amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33708) SubClassOf [is_substituent_group_from](http://purl.obolibrary.org/obo/chebi#is_substituent_group_from) some [amino acid](http://purl.obolibrary.org/obo/CHEBI_33709) + + + +### aminoacyltransferase activity `http://purl.obolibrary.org/obo/GO_0016755` + +#### Added +- [aminoacyltransferase activity](http://purl.obolibrary.org/obo/GO_0016755) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EC:2.3.2.-" + +- [aminoacyltransferase activity](http://purl.obolibrary.org/obo/GO_0016755) [label](http://www.w3.org/2000/01/rdf-schema#label) "aminoacyltransferase activity" + +- [aminoacyltransferase activity](http://purl.obolibrary.org/obo/GO_0016755) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [aminoacyltransferase activity](http://purl.obolibrary.org/obo/GO_0016755) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "transferase activity, transferring amino-acyl groups" + +- [aminoacyltransferase activity](http://purl.obolibrary.org/obo/GO_0016755) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0016755" + +- [aminoacyltransferase activity](http://purl.obolibrary.org/obo/GO_0016755) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- Class: [aminoacyltransferase activity](http://purl.obolibrary.org/obo/GO_0016755) + +- [aminoacyltransferase activity](http://purl.obolibrary.org/obo/GO_0016755) SubClassOf [catalytic activity, acting on a protein](http://purl.obolibrary.org/obo/GO_0140096) + +- [aminoacyltransferase activity](http://purl.obolibrary.org/obo/GO_0016755) SubClassOf [acyltransferase activity](http://purl.obolibrary.org/obo/GO_0016746) + + +### aminoalkylindole `http://purl.obolibrary.org/obo/CHEBI_38631` +#### Removed +- [aminoalkylindole](http://purl.obolibrary.org/obo/CHEBI_38631) [label](http://www.w3.org/2000/01/rdf-schema#label) "aminoalkylindole" + +- [aminoalkylindole](http://purl.obolibrary.org/obo/CHEBI_38631) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22503" + +- [aminoalkylindole](http://purl.obolibrary.org/obo/CHEBI_38631) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24792" + +- [aminoalkylindole](http://purl.obolibrary.org/obo/CHEBI_38631) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:38631" + +- [aminoalkylindole](http://purl.obolibrary.org/obo/CHEBI_38631) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [aminoalkylindole](http://purl.obolibrary.org/obo/CHEBI_38631) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aminoalkylindoles" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [aminoalkylindole](http://purl.obolibrary.org/obo/CHEBI_38631) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [aminoalkylindole](http://purl.obolibrary.org/obo/CHEBI_38631) + +- [aminoalkylindole](http://purl.obolibrary.org/obo/CHEBI_38631) SubClassOf [indoles](http://purl.obolibrary.org/obo/CHEBI_24828) + + + +### aminoglycan `http://purl.obolibrary.org/obo/CHEBI_22506` +#### Removed +- [aminoglycan](http://purl.obolibrary.org/obo/CHEBI_22506) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:22506" + +- [aminoglycan](http://purl.obolibrary.org/obo/CHEBI_22506) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aminoglycans" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [aminoglycan](http://purl.obolibrary.org/obo/CHEBI_22506) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [aminoglycan](http://purl.obolibrary.org/obo/CHEBI_22506) [label](http://www.w3.org/2000/01/rdf-schema#label) "aminoglycan" + +- [aminoglycan](http://purl.obolibrary.org/obo/CHEBI_22506) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [aminoglycan](http://purl.obolibrary.org/obo/CHEBI_22506) + +- [aminoglycan](http://purl.obolibrary.org/obo/CHEBI_22506) SubClassOf [polysaccharide derivative](http://purl.obolibrary.org/obo/CHEBI_65212) + +- [aminoglycan](http://purl.obolibrary.org/obo/CHEBI_22506) SubClassOf [organonitrogen compound](http://purl.obolibrary.org/obo/CHEBI_35352) + + + +### aminoglycan biosynthetic process `http://purl.obolibrary.org/obo/GO_0006023` +#### Removed +- [aminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006023) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [aminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006023) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [aminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006023) [label](http://www.w3.org/2000/01/rdf-schema#label) "aminoglycan biosynthetic process" + +- [aminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006023) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aminoglycan anabolism" + +- [aminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006023) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aminoglycan formation" + +- [aminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006023) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006023" + +- [aminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006023) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aminoglycan biosynthesis" + +- [aminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006023) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aminoglycan synthesis" + +- Class: [aminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006023) + +- [aminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006023) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [aminoglycan](http://purl.obolibrary.org/obo/CHEBI_22506)) + +- [aminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006023) SubClassOf [organonitrogen compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901566) + +- [aminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006023) SubClassOf [carbohydrate derivative biosynthetic process](http://purl.obolibrary.org/obo/GO_1901137) + +- [aminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006023) SubClassOf [macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0009059) + +- [aminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006023) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [aminoglycan](http://purl.obolibrary.org/obo/CHEBI_22506) + +- [aminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006023) SubClassOf [aminoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0006022) + + + +### aminoglycan catabolic process `http://purl.obolibrary.org/obo/GO_0006026` +#### Removed +- [aminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006026) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aminoglycan degradation" + +- [aminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006026) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006026" + +- [aminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006026) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [aminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006026) [label](http://www.w3.org/2000/01/rdf-schema#label) "aminoglycan catabolic process" + +- [aminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006026) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aminoglycan breakdown" + +- [aminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006026) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aminoglycan catabolism" + +- [aminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006026) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- Class: [aminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006026) + +- [aminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006026) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [aminoglycan](http://purl.obolibrary.org/obo/CHEBI_22506)) + +- [aminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006026) SubClassOf [macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0009057) + +- [aminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006026) SubClassOf [aminoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0006022) + +- [aminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006026) SubClassOf [organonitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_1901565) + +- [aminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006026) SubClassOf [carbohydrate derivative catabolic process](http://purl.obolibrary.org/obo/GO_1901136) + +- [aminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006026) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [aminoglycan](http://purl.obolibrary.org/obo/CHEBI_22506) + + + +### aminoglycan metabolic process `http://purl.obolibrary.org/obo/GO_0006022` +#### Removed +- [aminoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0006022) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aminoglycan metabolism" + +- [aminoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0006022) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [aminoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0006022) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006022" + +- [aminoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0006022) [label](http://www.w3.org/2000/01/rdf-schema#label) "aminoglycan metabolic process" + +- [aminoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0006022) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [aminoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0006022) + +- [aminoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0006022) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [aminoglycan](http://purl.obolibrary.org/obo/CHEBI_22506)) + +- [aminoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0006022) SubClassOf [carbohydrate derivative metabolic process](http://purl.obolibrary.org/obo/GO_1901135) + +- [aminoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0006022) SubClassOf [organonitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_1901564) + +- [aminoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0006022) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [aminoglycan](http://purl.obolibrary.org/obo/CHEBI_22506) + +- [aminoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0006022) SubClassOf [macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0043170) + + + +### ammonia `http://purl.obolibrary.org/obo/CHEBI_16134` +#### Removed +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "17.02655" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:16134" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15554424" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13406" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22130175" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H]N([H])[H]" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7664-41-7" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [mass](http://purl.obolibrary.org/obo/chebi/mass) "17.03056" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22443779" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18670398" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:3587154" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:44269" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "AMMONIA" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22290316" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11746427" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11540049" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:4625" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17025297" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22385337" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "QGZKDVFQNNGYKY-UHFFFAOYSA-N" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "R-717" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms." + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:44404" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ammonia" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22002069" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000051" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22342082" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:AMMONIA" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:3587154" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15969015" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22533" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:7434" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ammoniak" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7664-41-7" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22100291" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15094021" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NH3" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:110589" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16842901" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16050680" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "azane" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "amoniaco" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22081570" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16349403" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "spirit of hartshorn" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ammoniac" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17737668" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11783653" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[NH3]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MolBase" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D02916" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17569513" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:13753780" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:NH3" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13405" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:79" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11139349" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:44284" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16348008" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15092448" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22150211" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22240068" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Ammonia" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16664306" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [label](http://www.w3.org/2000/01/rdf-schema#label) "ammonia" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22560242" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MolBase:930" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13407" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00014" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17439666" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:14663195" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16008360" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22088435" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7664-41-7" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NH3" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ammonia" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13771" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16614889" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [formula](http://purl.obolibrary.org/obo/chebi/formula) "H3N" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NH3" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/H3N/h1H3" + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00007267" + +- Class: [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) SubClassOf [mononuclear parent hydride](http://purl.obolibrary.org/obo/CHEBI_37176) + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) SubClassOf [gas molecular entity](http://purl.obolibrary.org/obo/CHEBI_138675) + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) SubClassOf [azane](http://purl.obolibrary.org/obo/CHEBI_35107) + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [EC 3.5.1.4 (amidase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_77941) + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [refrigerant](http://purl.obolibrary.org/obo/CHEBI_78433) + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [nucleophilic reagent](http://purl.obolibrary.org/obo/CHEBI_59740) + +- [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) + + + +### ammonium `http://purl.obolibrary.org/obo/CHEBI_28938` +#### Removed +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22534" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/H3N/h1H3/p+1" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19596600" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19716251" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22562341" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [label](http://www.w3.org/2000/01/rdf-schema#label) "ammonium" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12096804" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19682559" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "18.03383" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21993530" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16345391" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [formula](http://purl.obolibrary.org/obo/chebi/formula) "H4N" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NH4(+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [mass](http://purl.obolibrary.org/obo/chebi/mass) "18.03850" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:84" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ammonium cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11341317" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ammonium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H][N+]([H])([H])[H]" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:NH4" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+1" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19199063" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:14879753" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17392693" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22524020" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:14798-03-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22265469" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:49783" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01342" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ammonium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MolBase:929" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ammonium(1+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[NH4](+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MolBase" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An onium cation obtained by protonation of ammonia." + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NH4+" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:14798-03-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:7435" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:AMMONIUM" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:14512268" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16903292" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18515490" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11319011" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:16093784" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "QGZKDVFQNNGYKY-UHFFFAOYSA-O" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ammonium ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "azanium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ammonium" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22631217" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:28938" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NH4(+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) SubClassOf [monovalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_60242) + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) SubClassOf [onium cation](http://purl.obolibrary.org/obo/CHEBI_50313) + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) SubClassOf [nitrogen hydride](http://purl.obolibrary.org/obo/CHEBI_35106) + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [cofactor](http://purl.obolibrary.org/obo/CHEBI_23357) + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) + +- [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + + + +### ammonium homeostasis `http://purl.obolibrary.org/obo/GO_0097272` +#### Removed +- [ammonium homeostasis](http://purl.obolibrary.org/obo/GO_0097272) SubClassOf [inorganic ion homeostasis](http://purl.obolibrary.org/obo/GO_0098771) + +#### Added +- [ammonium homeostasis](http://purl.obolibrary.org/obo/GO_0097272) SubClassOf [chemical homeostasis](http://purl.obolibrary.org/obo/GO_0048878) + + +### ammonium ion binding `http://purl.obolibrary.org/obo/GO_0070405` +#### Removed +- [ammonium ion binding](http://purl.obolibrary.org/obo/GO_0070405) SubClassOf [cation binding](http://purl.obolibrary.org/obo/GO_0043169) + +#### Added +- [ammonium ion binding](http://purl.obolibrary.org/obo/GO_0070405) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### ammonium ion derivative `http://purl.obolibrary.org/obo/CHEBI_35274` +#### Removed +- [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Ammonium, NH4(+), and derivatives formed by substitution by univalent groups." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ammonium ion derivatives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "azanium ion derivatives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "azanium ion derivative" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc)." + +- [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "azanium ions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35274" + +- [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) [label](http://www.w3.org/2000/01/rdf-schema#label) "ammonium ion derivative" + +- [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ammonium ions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- Class: [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) + +- [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) SubClassOf [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) + +- [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) SubClassOf [polyatomic cation](http://purl.obolibrary.org/obo/CHEBI_33702) + +- [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) SubClassOf [has_parent_hydride](http://purl.obolibrary.org/obo/chebi#has_parent_hydride) some [ammonium](http://purl.obolibrary.org/obo/CHEBI_28938) + + + +### ammonium transmembrane transport `http://purl.obolibrary.org/obo/GO_0072488` +#### Removed +- [ammonium transmembrane transport](http://purl.obolibrary.org/obo/GO_0072488) SubClassOf [nitrogen compound transport](http://purl.obolibrary.org/obo/GO_0071705) + +- [ammonium transmembrane transport](http://purl.obolibrary.org/obo/GO_0072488) SubClassOf [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) + +#### Added +- [ammonium transmembrane transport](http://purl.obolibrary.org/obo/GO_0072488) SubClassOf [transmembrane transport](http://purl.obolibrary.org/obo/GO_0055085) + + +### ammonium transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0008519` +#### Removed +- [ammonium transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008519) SubClassOf [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) + + + +### amniocyte `http://purl.obolibrary.org/obo/CL_0002323` +#### Removed +- [amniocyte](http://purl.obolibrary.org/obo/CL_0002323) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### amphiprotic solvent `http://purl.obolibrary.org/obo/CHEBI_48360` +#### Removed +- [amphiprotic solvent](http://purl.obolibrary.org/obo/CHEBI_48360) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:48360" + +- [amphiprotic solvent](http://purl.obolibrary.org/obo/CHEBI_48360) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "amphiprotic solvent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [amphiprotic solvent](http://purl.obolibrary.org/obo/CHEBI_48360) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Self-ionizing solvent possessing both characteristics of Bronsted acids and bases." + +- [amphiprotic solvent](http://purl.obolibrary.org/obo/CHEBI_48360) [label](http://www.w3.org/2000/01/rdf-schema#label) "amphiprotic solvent" + +- [amphiprotic solvent](http://purl.obolibrary.org/obo/CHEBI_48360) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [amphiprotic solvent](http://purl.obolibrary.org/obo/CHEBI_48360) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [amphiprotic solvent](http://purl.obolibrary.org/obo/CHEBI_48360) + +- [amphiprotic solvent](http://purl.obolibrary.org/obo/CHEBI_48360) SubClassOf [protophilic solvent](http://purl.obolibrary.org/obo/CHEBI_48359) + +- [amphiprotic solvent](http://purl.obolibrary.org/obo/CHEBI_48360) SubClassOf [protic solvent](http://purl.obolibrary.org/obo/CHEBI_48356) + + + +### androgen `http://purl.obolibrary.org/obo/CHEBI_50113` +#### Removed +- [androgen](http://purl.obolibrary.org/obo/CHEBI_50113) [label](http://www.w3.org/2000/01/rdf-schema#label) "androgen" + +- [androgen](http://purl.obolibrary.org/obo/CHEBI_50113) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50113" + +- [androgen](http://purl.obolibrary.org/obo/CHEBI_50113) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Androgen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [androgen](http://purl.obolibrary.org/obo/CHEBI_50113) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A sex hormone that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors." + +- [androgen](http://purl.obolibrary.org/obo/CHEBI_50113) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "androgenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [androgen](http://purl.obolibrary.org/obo/CHEBI_50113) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Androgene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [androgen](http://purl.obolibrary.org/obo/CHEBI_50113) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "androgene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [androgen](http://purl.obolibrary.org/obo/CHEBI_50113) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [androgen](http://purl.obolibrary.org/obo/CHEBI_50113) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [androgen](http://purl.obolibrary.org/obo/CHEBI_50113) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "androgeno" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [androgen](http://purl.obolibrary.org/obo/CHEBI_50113) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "androgenos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [androgen](http://purl.obolibrary.org/obo/CHEBI_50113) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "androgens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [androgen](http://purl.obolibrary.org/obo/CHEBI_50113) + +- [androgen](http://purl.obolibrary.org/obo/CHEBI_50113) SubClassOf [sex hormone](http://purl.obolibrary.org/obo/CHEBI_50112) + + + +### androstane `http://purl.obolibrary.org/obo/CHEBI_35509` +#### Removed +- [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35509" + +- [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:24887-75-0" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "260.25040" + +- [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C19H32" + +- [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) [label](http://www.w3.org/2000/01/rdf-schema#label) "androstane" + +- [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "QZLYKIGBANMMBK-FZFXZXLVSA-N" + +- [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LIPID_MAPS_instance:LMST02020000" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "LIPID MAPS" + +- [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "androstane" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H][C@@]12CCC3CCCC[C@]3(C)[C@@]1([H])CC[C@]1(C)CCC[C@@]21[H]" + +- [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:5247532" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) [mass](http://purl.obolibrary.org/obo/chebi/mass) "260.45738" + +- [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C19H32/c1-18-11-5-7-16(18)15-9-8-14-6-3-4-12-19(14,2)17(15)10-13-18/h14-17H,3-13H2,1-2H3/t14?,15-,16-,17-,18-,19-/m0/s1" + +- Class: [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) + +- [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) SubClassOf [steroid fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35508) + + + +### androstanoid `http://purl.obolibrary.org/obo/CHEBI_50402` +#### Removed +- [androstanoid](http://purl.obolibrary.org/obo/CHEBI_50402) [label](http://www.w3.org/2000/01/rdf-schema#label) "androstanoid" + +- [androstanoid](http://purl.obolibrary.org/obo/CHEBI_50402) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50402" + +- [androstanoid](http://purl.obolibrary.org/obo/CHEBI_50402) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [androstanoid](http://purl.obolibrary.org/obo/CHEBI_50402) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "androstanoids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [androstanoid](http://purl.obolibrary.org/obo/CHEBI_50402) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [androstanoid](http://purl.obolibrary.org/obo/CHEBI_50402) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any steroid based on an androstane skeleton and its derivatives." + +- Class: [androstanoid](http://purl.obolibrary.org/obo/CHEBI_50402) + +- [androstanoid](http://purl.obolibrary.org/obo/CHEBI_50402) SubClassOf [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) + +- [androstanoid](http://purl.obolibrary.org/obo/CHEBI_50402) SubClassOf [has_parent_hydride](http://purl.obolibrary.org/obo/chebi#has_parent_hydride) some [androstane](http://purl.obolibrary.org/obo/CHEBI_35509) + + + +### animal metabolite `http://purl.obolibrary.org/obo/CHEBI_75767` +#### Removed +- [animal metabolite](http://purl.obolibrary.org/obo/CHEBI_75767) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [animal metabolite](http://purl.obolibrary.org/obo/CHEBI_75767) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:77743" + +- [animal metabolite](http://purl.obolibrary.org/obo/CHEBI_75767) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:75767" + +- [animal metabolite](http://purl.obolibrary.org/obo/CHEBI_75767) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals." + +- [animal metabolite](http://purl.obolibrary.org/obo/CHEBI_75767) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "animal metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [animal metabolite](http://purl.obolibrary.org/obo/CHEBI_75767) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:77721" + +- [animal metabolite](http://purl.obolibrary.org/obo/CHEBI_75767) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [animal metabolite](http://purl.obolibrary.org/obo/CHEBI_75767) [label](http://www.w3.org/2000/01/rdf-schema#label) "animal metabolite" + +- Class: [animal metabolite](http://purl.obolibrary.org/obo/CHEBI_75767) + +- [animal metabolite](http://purl.obolibrary.org/obo/CHEBI_75767) SubClassOf [eukaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75763) + + + +### anion `http://purl.obolibrary.org/obo/CHEBI_22563` +#### Removed +- [anion](http://purl.obolibrary.org/obo/CHEBI_22563) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aniones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anion](http://purl.obolibrary.org/obo/CHEBI_22563) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [anion](http://purl.obolibrary.org/obo/CHEBI_22563) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [anion](http://purl.obolibrary.org/obo/CHEBI_22563) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anion](http://purl.obolibrary.org/obo/CHEBI_22563) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Anionen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anion](http://purl.obolibrary.org/obo/CHEBI_22563) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:22563" + +- [anion](http://purl.obolibrary.org/obo/CHEBI_22563) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A monoatomic or polyatomic species having one or more elementary charges of the electron." + +- [anion](http://purl.obolibrary.org/obo/CHEBI_22563) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [anion](http://purl.obolibrary.org/obo/CHEBI_22563) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anion](http://purl.obolibrary.org/obo/CHEBI_22563) [label](http://www.w3.org/2000/01/rdf-schema#label) "anion" + +- [anion](http://purl.obolibrary.org/obo/CHEBI_22563) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [anion](http://purl.obolibrary.org/obo/CHEBI_22563) + +- [anion](http://purl.obolibrary.org/obo/CHEBI_22563) SubClassOf [ion](http://purl.obolibrary.org/obo/CHEBI_24870) + + + +### anion binding `http://purl.obolibrary.org/obo/GO_0043168` +#### Removed +- [anion binding](http://purl.obolibrary.org/obo/GO_0043168) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0043168" + +- [anion binding](http://purl.obolibrary.org/obo/GO_0043168) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to an anion, a charged atom or group of atoms with a net negative charge." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [anion binding](http://purl.obolibrary.org/obo/GO_0043168) [label](http://www.w3.org/2000/01/rdf-schema#label) "anion binding" + +- [anion binding](http://purl.obolibrary.org/obo/GO_0043168) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- Class: [anion binding](http://purl.obolibrary.org/obo/GO_0043168) + +- [anion binding](http://purl.obolibrary.org/obo/GO_0043168) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [anion](http://purl.obolibrary.org/obo/CHEBI_22563)) + +- [anion binding](http://purl.obolibrary.org/obo/GO_0043168) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [anion](http://purl.obolibrary.org/obo/CHEBI_22563) + +- [anion binding](http://purl.obolibrary.org/obo/GO_0043168) SubClassOf [ion binding](http://purl.obolibrary.org/obo/GO_0043167) + + + +### anti-inflammatory agent `http://purl.obolibrary.org/obo/CHEBI_67079` +#### Removed +- [anti-inflammatory agent](http://purl.obolibrary.org/obo/CHEBI_67079) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antiinflammatory agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anti-inflammatory agent](http://purl.obolibrary.org/obo/CHEBI_67079) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:67079" + +- [anti-inflammatory agent](http://purl.obolibrary.org/obo/CHEBI_67079) [label](http://www.w3.org/2000/01/rdf-schema#label) "anti-inflammatory agent" + +- [anti-inflammatory agent](http://purl.obolibrary.org/obo/CHEBI_67079) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any compound that has anti-inflammatory effects." + +- [anti-inflammatory agent](http://purl.obolibrary.org/obo/CHEBI_67079) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [anti-inflammatory agent](http://purl.obolibrary.org/obo/CHEBI_67079) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-inflammatory agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anti-inflammatory agent](http://purl.obolibrary.org/obo/CHEBI_67079) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antiinflammatory agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anti-inflammatory agent](http://purl.obolibrary.org/obo/CHEBI_67079) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [anti-inflammatory agent](http://purl.obolibrary.org/obo/CHEBI_67079) + +- [anti-inflammatory agent](http://purl.obolibrary.org/obo/CHEBI_67079) SubClassOf [application](http://purl.obolibrary.org/obo/CHEBI_33232) + + + +### anti-inflammatory drug `http://purl.obolibrary.org/obo/CHEBI_35472` +#### Removed +- [anti-inflammatory drug](http://purl.obolibrary.org/obo/CHEBI_35472) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [anti-inflammatory drug](http://purl.obolibrary.org/obo/CHEBI_35472) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A substance that reduces or suppresses inflammation." + +- [anti-inflammatory drug](http://purl.obolibrary.org/obo/CHEBI_35472) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antiinflammatory drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anti-inflammatory drug](http://purl.obolibrary.org/obo/CHEBI_35472) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antiinflammatory agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anti-inflammatory drug](http://purl.obolibrary.org/obo/CHEBI_35472) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-inflammatory drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anti-inflammatory drug](http://purl.obolibrary.org/obo/CHEBI_35472) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antiinflammatory drug" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anti-inflammatory drug](http://purl.obolibrary.org/obo/CHEBI_35472) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35472" + +- [anti-inflammatory drug](http://purl.obolibrary.org/obo/CHEBI_35472) [label](http://www.w3.org/2000/01/rdf-schema#label) "anti-inflammatory drug" + +- [anti-inflammatory drug](http://purl.obolibrary.org/obo/CHEBI_35472) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [anti-inflammatory drug](http://purl.obolibrary.org/obo/CHEBI_35472) + +- [anti-inflammatory drug](http://purl.obolibrary.org/obo/CHEBI_35472) SubClassOf [anti-inflammatory agent](http://purl.obolibrary.org/obo/CHEBI_67079) + +- [anti-inflammatory drug](http://purl.obolibrary.org/obo/CHEBI_35472) SubClassOf [drug](http://purl.obolibrary.org/obo/CHEBI_23888) + + + +### antiatherogenic agent `http://purl.obolibrary.org/obo/CHEBI_50855` +#### Removed +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antiatherogenic drug" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:14592471" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:3288054" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21172387" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-atherogenic drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "antiatherogenic agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16366593" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-atherogenic agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21649483" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9796331" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antiatherogenic drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17990280" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50855" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21074432" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antiatherogenic agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [label](http://www.w3.org/2000/01/rdf-schema#label) "antiatherogenic agent" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A cardiovascular drug that prevents atherogenesis, the accumulation of lipid-containing plaques on the innermost layers of the arteries. Compare with antiatherosclerotic agent." + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-atherogenic drug" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-atherogenic agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20222342" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- Class: [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) + +- [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) SubClassOf [cardiovascular drug](http://purl.obolibrary.org/obo/CHEBI_35554) + + + +### antibacterial agent `http://purl.obolibrary.org/obo/CHEBI_33282` +#### Removed +- [antibacterial agent](http://purl.obolibrary.org/obo/CHEBI_33282) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33282" + +- [antibacterial agent](http://purl.obolibrary.org/obo/CHEBI_33282) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bactericide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antibacterial agent](http://purl.obolibrary.org/obo/CHEBI_33282) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [antibacterial agent](http://purl.obolibrary.org/obo/CHEBI_33282) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [antibacterial agent](http://purl.obolibrary.org/obo/CHEBI_33282) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antibacterials" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antibacterial agent](http://purl.obolibrary.org/obo/CHEBI_33282) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bactericides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antibacterial agent](http://purl.obolibrary.org/obo/CHEBI_33282) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A substance (or active part thereof) that kills or slows the growth of bacteria." + +- [antibacterial agent](http://purl.obolibrary.org/obo/CHEBI_33282) [label](http://www.w3.org/2000/01/rdf-schema#label) "antibacterial agent" + +- [antibacterial agent](http://purl.obolibrary.org/obo/CHEBI_33282) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antibacterial agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [antibacterial agent](http://purl.obolibrary.org/obo/CHEBI_33282) + +- [antibacterial agent](http://purl.obolibrary.org/obo/CHEBI_33282) SubClassOf [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) + + + +### anticonvulsant `http://purl.obolibrary.org/obo/CHEBI_35623` +#### Removed +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [label](http://www.w3.org/2000/01/rdf-schema#label) "anticonvulsant" + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-convulsive agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Antikonvulsiva" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Antiepileptika" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antiepileptiques" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antiepileptics" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Antiepileptikum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Antikonvulsivum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-convulsants" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antiepileptique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antiepileptic" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anticonvulsants" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-convulsant" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anticonvulsive agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anticonvulsive agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-convulsive agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A drug used to prevent seizures or reduce their severity." + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35623" + +- Class: [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) + +- [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) SubClassOf [central nervous system depressant](http://purl.obolibrary.org/obo/CHEBI_35488) + + + +### antimicrobial agent `http://purl.obolibrary.org/obo/CHEBI_33281` +#### Removed +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antimicrobials" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22958833" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antimicrobial agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "microbicides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans." + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22849276" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Antibiotikum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Antibiotika" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22849268" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antibiotique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33281" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antibiotic" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22439833" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22582" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12964249" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [label](http://www.w3.org/2000/01/rdf-schema#label) "antimicrobial agent" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antimicrobial" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "microbicide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antibiotics" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22117953" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- Class: [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) + +- [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) SubClassOf [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) + + + +### antimicrobial food preservative `http://purl.obolibrary.org/obo/CHEBI_65256` +#### Removed +- [antimicrobial food preservative](http://purl.obolibrary.org/obo/CHEBI_65256) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [antimicrobial food preservative](http://purl.obolibrary.org/obo/CHEBI_65256) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [antimicrobial food preservative](http://purl.obolibrary.org/obo/CHEBI_65256) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antimicrobial preservative" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antimicrobial food preservative](http://purl.obolibrary.org/obo/CHEBI_65256) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299)." + +- [antimicrobial food preservative](http://purl.obolibrary.org/obo/CHEBI_65256) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:65256" + +- [antimicrobial food preservative](http://purl.obolibrary.org/obo/CHEBI_65256) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antimicrobial preservatives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antimicrobial food preservative](http://purl.obolibrary.org/obo/CHEBI_65256) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antimicrobial food preservatives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antimicrobial food preservative](http://purl.obolibrary.org/obo/CHEBI_65256) [label](http://www.w3.org/2000/01/rdf-schema#label) "antimicrobial food preservative" + +- Class: [antimicrobial food preservative](http://purl.obolibrary.org/obo/CHEBI_65256) + +- [antimicrobial food preservative](http://purl.obolibrary.org/obo/CHEBI_65256) SubClassOf [antimicrobial agent](http://purl.obolibrary.org/obo/CHEBI_33281) + +- [antimicrobial food preservative](http://purl.obolibrary.org/obo/CHEBI_65256) SubClassOf [food preservative](http://purl.obolibrary.org/obo/CHEBI_65255) + + + +### antineoplastic agent `http://purl.obolibrary.org/obo/CHEBI_35610` +#### Removed +- [antineoplastic agent](http://purl.obolibrary.org/obo/CHEBI_35610) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anticancer agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antineoplastic agent](http://purl.obolibrary.org/obo/CHEBI_35610) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antineoplastic" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antineoplastic agent](http://purl.obolibrary.org/obo/CHEBI_35610) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A substance that inhibits or prevents the proliferation of neoplasms." + +- [antineoplastic agent](http://purl.obolibrary.org/obo/CHEBI_35610) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antineoplastic agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antineoplastic agent](http://purl.obolibrary.org/obo/CHEBI_35610) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35610" + +- [antineoplastic agent](http://purl.obolibrary.org/obo/CHEBI_35610) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cytostatic" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antineoplastic agent](http://purl.obolibrary.org/obo/CHEBI_35610) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [antineoplastic agent](http://purl.obolibrary.org/obo/CHEBI_35610) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anticancer agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antineoplastic agent](http://purl.obolibrary.org/obo/CHEBI_35610) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [antineoplastic agent](http://purl.obolibrary.org/obo/CHEBI_35610) [label](http://www.w3.org/2000/01/rdf-schema#label) "antineoplastic agent" + +- Class: [antineoplastic agent](http://purl.obolibrary.org/obo/CHEBI_35610) + +- [antineoplastic agent](http://purl.obolibrary.org/obo/CHEBI_35610) SubClassOf [drug](http://purl.obolibrary.org/obo/CHEBI_23888) + + + +### antioxidant `http://purl.obolibrary.org/obo/CHEBI_22586` +#### Removed +- [antioxidant](http://purl.obolibrary.org/obo/CHEBI_22586) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antioxidants" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antioxidant](http://purl.obolibrary.org/obo/CHEBI_22586) [label](http://www.w3.org/2000/01/rdf-schema#label) "antioxidant" + +- [antioxidant](http://purl.obolibrary.org/obo/CHEBI_22586) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [antioxidant](http://purl.obolibrary.org/obo/CHEBI_22586) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:22586" + +- [antioxidant](http://purl.obolibrary.org/obo/CHEBI_22586) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antoxidant" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antioxidant](http://purl.obolibrary.org/obo/CHEBI_22586) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides." + +- [antioxidant](http://purl.obolibrary.org/obo/CHEBI_22586) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antioxydant" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [antioxidant](http://purl.obolibrary.org/obo/CHEBI_22586) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [antioxidant](http://purl.obolibrary.org/obo/CHEBI_22586) + +- [antioxidant](http://purl.obolibrary.org/obo/CHEBI_22586) SubClassOf [chemical role](http://purl.obolibrary.org/obo/CHEBI_51086) + + + +### apatite `http://purl.obolibrary.org/obo/CHEBI_52254` +#### Removed +- [apatite](http://purl.obolibrary.org/obo/CHEBI_52254) [label](http://www.w3.org/2000/01/rdf-schema#label) "apatite" + +- [apatite](http://purl.obolibrary.org/obo/CHEBI_52254) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [apatite](http://purl.obolibrary.org/obo/CHEBI_52254) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:52254" + +- [apatite](http://purl.obolibrary.org/obo/CHEBI_52254) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydroxyapatite" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [apatite](http://purl.obolibrary.org/obo/CHEBI_52254) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A phosphate mineral with the general formula Ca5(PO4)3X where X = OH, F or Cl." + +- [apatite](http://purl.obolibrary.org/obo/CHEBI_52254) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [apatite](http://purl.obolibrary.org/obo/CHEBI_52254) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0033610" + +- Class: [apatite](http://purl.obolibrary.org/obo/CHEBI_52254) + +- [apatite](http://purl.obolibrary.org/obo/CHEBI_52254) SubClassOf [phosphate mineral](http://purl.obolibrary.org/obo/CHEBI_46723) + + + +### apolipoprotein `http://purl.obolibrary.org/obo/CHEBI_39015` +#### Removed +- [apolipoprotein](http://purl.obolibrary.org/obo/CHEBI_39015) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Protein component on the surface of lipoprotein." + +- [apolipoprotein](http://purl.obolibrary.org/obo/CHEBI_39015) [label](http://www.w3.org/2000/01/rdf-schema#label) "apolipoprotein" + +- [apolipoprotein](http://purl.obolibrary.org/obo/CHEBI_39015) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [apolipoprotein](http://purl.obolibrary.org/obo/CHEBI_39015) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "apolipoproteins" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [apolipoprotein](http://purl.obolibrary.org/obo/CHEBI_39015) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:39015" + +- [apolipoprotein](http://purl.obolibrary.org/obo/CHEBI_39015) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [apolipoprotein](http://purl.obolibrary.org/obo/CHEBI_39015) + +- [apolipoprotein](http://purl.obolibrary.org/obo/CHEBI_39015) SubClassOf [apoprotein](http://purl.obolibrary.org/obo/CHEBI_13850) + + + +### apolipoprotein binding `http://purl.obolibrary.org/obo/GO_0034185` +#### Removed +- [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185) [label](http://www.w3.org/2000/01/rdf-schema#label) "apolipoprotein binding" + +- [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to an apolipoprotein, the protein component of a lipoprotein complex." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:rl" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:BHF" + +- [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185) [never in taxon](http://purl.obolibrary.org/obo/RO_0002161) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) + +- [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0034185" + +- Class: [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185) + +- [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185) DisjointWith [in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) + +- [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [apolipoprotein](http://purl.obolibrary.org/obo/CHEBI_39015)) + +- [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185) SubClassOf [protein binding](http://purl.obolibrary.org/obo/GO_0005515) + +- [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [apolipoprotein](http://purl.obolibrary.org/obo/CHEBI_39015) + +- [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185) SubClassOf [in taxon](http://purl.obolibrary.org/obo/RO_0002162) some (not ([Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751))) + +- [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185) SubClassOf not ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751)) + + + +### apolipoprotein receptor activity `http://purl.obolibrary.org/obo/GO_0030226` +#### Removed +- [apolipoprotein receptor activity](http://purl.obolibrary.org/obo/GO_0030226) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0030226" + +- [apolipoprotein receptor activity](http://purl.obolibrary.org/obo/GO_0030226) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [apolipoprotein receptor activity](http://purl.obolibrary.org/obo/GO_0030226) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Combining with an apolipoprotein to initiate a change in cell activity." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [apolipoprotein receptor activity](http://purl.obolibrary.org/obo/GO_0030226) [label](http://www.w3.org/2000/01/rdf-schema#label) "apolipoprotein receptor activity" + +- Class: [apolipoprotein receptor activity](http://purl.obolibrary.org/obo/GO_0030226) + +- [apolipoprotein receptor activity](http://purl.obolibrary.org/obo/GO_0030226) EquivalentTo [cargo receptor activity](http://purl.obolibrary.org/obo/GO_0038024) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [apolipoprotein](http://purl.obolibrary.org/obo/CHEBI_39015)) + +- [apolipoprotein receptor activity](http://purl.obolibrary.org/obo/GO_0030226) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [apolipoprotein](http://purl.obolibrary.org/obo/CHEBI_39015) + +- [apolipoprotein receptor activity](http://purl.obolibrary.org/obo/GO_0030226) SubClassOf [cargo receptor activity](http://purl.obolibrary.org/obo/GO_0038024) + +- [apolipoprotein receptor activity](http://purl.obolibrary.org/obo/GO_0030226) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185) + + + +### apoprotein `http://purl.obolibrary.org/obo/CHEBI_13850` +#### Removed +- [apoprotein](http://purl.obolibrary.org/obo/CHEBI_13850) [label](http://www.w3.org/2000/01/rdf-schema#label) "apoprotein" + +- [apoprotein](http://purl.obolibrary.org/obo/CHEBI_13850) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C16240" + +- [apoprotein](http://purl.obolibrary.org/obo/CHEBI_13850) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:13850" + +- [apoprotein](http://purl.obolibrary.org/obo/CHEBI_13850) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "apoprotein" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [apoprotein](http://purl.obolibrary.org/obo/CHEBI_13850) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An apoprotein is a protein devoid of its characteristic prosthetic group or metal." + +- [apoprotein](http://purl.obolibrary.org/obo/CHEBI_13850) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [apoprotein](http://purl.obolibrary.org/obo/CHEBI_13850) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [apoprotein](http://purl.obolibrary.org/obo/CHEBI_13850) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "apoproteins" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [apoprotein](http://purl.obolibrary.org/obo/CHEBI_13850) + +- [apoprotein](http://purl.obolibrary.org/obo/CHEBI_13850) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [apoprotein](http://purl.obolibrary.org/obo/CHEBI_13850) SubClassOf [simple protein](http://purl.obolibrary.org/obo/CHEBI_38560) + + + +### apoptosis inducer `http://purl.obolibrary.org/obo/CHEBI_68495` +#### Removed +- [apoptosis inducer](http://purl.obolibrary.org/obo/CHEBI_68495) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms." + +- [apoptosis inducer](http://purl.obolibrary.org/obo/CHEBI_68495) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Type I cell-death inducers" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [apoptosis inducer](http://purl.obolibrary.org/obo/CHEBI_68495) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Type I programmed cell-death inducer" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [apoptosis inducer](http://purl.obolibrary.org/obo/CHEBI_68495) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Type I programmed cell-death inducers" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [apoptosis inducer](http://purl.obolibrary.org/obo/CHEBI_68495) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [apoptosis inducer](http://purl.obolibrary.org/obo/CHEBI_68495) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "apoptosis inducers" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [apoptosis inducer](http://purl.obolibrary.org/obo/CHEBI_68495) [label](http://www.w3.org/2000/01/rdf-schema#label) "apoptosis inducer" + +- [apoptosis inducer](http://purl.obolibrary.org/obo/CHEBI_68495) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [apoptosis inducer](http://purl.obolibrary.org/obo/CHEBI_68495) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:68495" + +- [apoptosis inducer](http://purl.obolibrary.org/obo/CHEBI_68495) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Type I cell-death inducer" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [apoptosis inducer](http://purl.obolibrary.org/obo/CHEBI_68495) + +- [apoptosis inducer](http://purl.obolibrary.org/obo/CHEBI_68495) SubClassOf [biochemical role](http://purl.obolibrary.org/obo/CHEBI_52206) + + + +### appetite enhancer `http://purl.obolibrary.org/obo/CHEBI_50779` +#### Removed +- [appetite enhancer](http://purl.obolibrary.org/obo/CHEBI_50779) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "appetite enhancing drug" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [appetite enhancer](http://purl.obolibrary.org/obo/CHEBI_50779) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [appetite enhancer](http://purl.obolibrary.org/obo/CHEBI_50779) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "orexigenic" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [appetite enhancer](http://purl.obolibrary.org/obo/CHEBI_50779) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50779" + +- [appetite enhancer](http://purl.obolibrary.org/obo/CHEBI_50779) [label](http://www.w3.org/2000/01/rdf-schema#label) "appetite enhancer" + +- [appetite enhancer](http://purl.obolibrary.org/obo/CHEBI_50779) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Appetite_stimulants" + +- [appetite enhancer](http://purl.obolibrary.org/obo/CHEBI_50779) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [appetite enhancer](http://purl.obolibrary.org/obo/CHEBI_50779) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "appetite stimulant" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [appetite enhancer](http://purl.obolibrary.org/obo/CHEBI_50779) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A drug which increases appetite." + +- Class: [appetite enhancer](http://purl.obolibrary.org/obo/CHEBI_50779) + +- [appetite enhancer](http://purl.obolibrary.org/obo/CHEBI_50779) SubClassOf [appetite regulator](http://purl.obolibrary.org/obo/CHEBI_50780) + + + +### appetite regulator `http://purl.obolibrary.org/obo/CHEBI_50780` +#### Removed +- [appetite regulator](http://purl.obolibrary.org/obo/CHEBI_50780) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [appetite regulator](http://purl.obolibrary.org/obo/CHEBI_50780) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50780" + +- [appetite regulator](http://purl.obolibrary.org/obo/CHEBI_50780) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An agent which regulates the physiologic mechanisms that control the appetite and food intake." + +- [appetite regulator](http://purl.obolibrary.org/obo/CHEBI_50780) [label](http://www.w3.org/2000/01/rdf-schema#label) "appetite regulator" + +- [appetite regulator](http://purl.obolibrary.org/obo/CHEBI_50780) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [appetite regulator](http://purl.obolibrary.org/obo/CHEBI_50780) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "appetite regulators" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [appetite regulator](http://purl.obolibrary.org/obo/CHEBI_50780) + +- [appetite regulator](http://purl.obolibrary.org/obo/CHEBI_50780) SubClassOf [drug](http://purl.obolibrary.org/obo/CHEBI_23888) + + + +### application `http://purl.obolibrary.org/obo/CHEBI_33232` +#### Removed +- [application](http://purl.obolibrary.org/obo/CHEBI_33232) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Intended use of the molecular entity or part thereof by humans." + +- [application](http://purl.obolibrary.org/obo/CHEBI_33232) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [application](http://purl.obolibrary.org/obo/CHEBI_33232) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33232" + +- [application](http://purl.obolibrary.org/obo/CHEBI_33232) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [application](http://purl.obolibrary.org/obo/CHEBI_33232) [label](http://www.w3.org/2000/01/rdf-schema#label) "application" + +- Class: [application](http://purl.obolibrary.org/obo/CHEBI_33232) + +- [application](http://purl.obolibrary.org/obo/CHEBI_33232) SubClassOf [role](http://purl.obolibrary.org/obo/BFO_0000023) + +- [application](http://purl.obolibrary.org/obo/CHEBI_33232) SubClassOf [role](http://purl.obolibrary.org/obo/CHEBI_50906) + + + +### aralkylamino compound `http://purl.obolibrary.org/obo/CHEBI_64365` +#### Removed +- [aralkylamino compound](http://purl.obolibrary.org/obo/CHEBI_64365) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [aralkylamino compound](http://purl.obolibrary.org/obo/CHEBI_64365) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An organic amino compound in which an aminoalkyl group is linked to an arene." + +- [aralkylamino compound](http://purl.obolibrary.org/obo/CHEBI_64365) [label](http://www.w3.org/2000/01/rdf-schema#label) "aralkylamino compound" + +- [aralkylamino compound](http://purl.obolibrary.org/obo/CHEBI_64365) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aralkylamino compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [aralkylamino compound](http://purl.obolibrary.org/obo/CHEBI_64365) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [aralkylamino compound](http://purl.obolibrary.org/obo/CHEBI_64365) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:64365" + +- Class: [aralkylamino compound](http://purl.obolibrary.org/obo/CHEBI_64365) + +- [aralkylamino compound](http://purl.obolibrary.org/obo/CHEBI_64365) SubClassOf [organic amino compound](http://purl.obolibrary.org/obo/CHEBI_50047) + + + +### aromatic compound `http://purl.obolibrary.org/obo/CHEBI_33655` +#### Removed +- [aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33655) [label](http://www.w3.org/2000/01/rdf-schema#label) "aromatic compound" + +- [aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33655) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33655) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aromatic molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33655) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aromatic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33655) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aromatics" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33655) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aromatische Verbindungen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33655) SubClassOf [cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33595) + + + +### astringent `http://purl.obolibrary.org/obo/CHEBI_74783` +#### Removed +- [astringent](http://purl.obolibrary.org/obo/CHEBI_74783) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "adstringent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [astringent](http://purl.obolibrary.org/obo/CHEBI_74783) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Astringent" + +- [astringent](http://purl.obolibrary.org/obo/CHEBI_74783) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "astringents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [astringent](http://purl.obolibrary.org/obo/CHEBI_74783) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:74783" + +- [astringent](http://purl.obolibrary.org/obo/CHEBI_74783) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [astringent](http://purl.obolibrary.org/obo/CHEBI_74783) [label](http://www.w3.org/2000/01/rdf-schema#label) "astringent" + +- [astringent](http://purl.obolibrary.org/obo/CHEBI_74783) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions." + +- [astringent](http://purl.obolibrary.org/obo/CHEBI_74783) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "adstringents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [astringent](http://purl.obolibrary.org/obo/CHEBI_74783) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [astringent](http://purl.obolibrary.org/obo/CHEBI_74783) + +- [astringent](http://purl.obolibrary.org/obo/CHEBI_74783) SubClassOf [drug](http://purl.obolibrary.org/obo/CHEBI_23888) + + + +### atom `http://purl.obolibrary.org/obo/CHEBI_33250` +#### Removed +- [atom](http://purl.obolibrary.org/obo/CHEBI_33250) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23907" + +- [atom](http://purl.obolibrary.org/obo/CHEBI_33250) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22671" + +- [atom](http://purl.obolibrary.org/obo/CHEBI_33250) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "atomo" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [atom](http://purl.obolibrary.org/obo/CHEBI_33250) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [atom](http://purl.obolibrary.org/obo/CHEBI_33250) [label](http://www.w3.org/2000/01/rdf-schema#label) "atom" + +- [atom](http://purl.obolibrary.org/obo/CHEBI_33250) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A chemical entity constituting the smallest component of an element having the chemical properties of the element." + +- [atom](http://purl.obolibrary.org/obo/CHEBI_33250) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [atom](http://purl.obolibrary.org/obo/CHEBI_33250) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "atoms" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [atom](http://purl.obolibrary.org/obo/CHEBI_33250) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "atome" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [atom](http://purl.obolibrary.org/obo/CHEBI_33250) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33250" + +- [atom](http://purl.obolibrary.org/obo/CHEBI_33250) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "atomus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [atom](http://purl.obolibrary.org/obo/CHEBI_33250) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "elements" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [atom](http://purl.obolibrary.org/obo/CHEBI_33250) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "atom" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [atom](http://purl.obolibrary.org/obo/CHEBI_33250) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "element" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [atom](http://purl.obolibrary.org/obo/CHEBI_33250) + +- [atom](http://purl.obolibrary.org/obo/CHEBI_33250) SubClassOf [chemical entity](http://purl.obolibrary.org/obo/CHEBI_24431) + +- [atom](http://purl.obolibrary.org/obo/CHEBI_33250) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [electron](http://purl.obolibrary.org/obo/CHEBI_10545) + +- [atom](http://purl.obolibrary.org/obo/CHEBI_33250) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) + + + +### atomic nucleus `http://purl.obolibrary.org/obo/CHEBI_33252` +#### Removed +- [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33252" + +- [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons." + +- [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "noyau atomique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleo" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Kern" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Atomkern" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) [label](http://www.w3.org/2000/01/rdf-schema#label) "atomic nucleus" + +- [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus atomi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "noyau" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleo atomico" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) + +- [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nucleon](http://purl.obolibrary.org/obo/CHEBI_33253) + +- [atomic nucleus](http://purl.obolibrary.org/obo/CHEBI_33252) SubClassOf [nuclear particle](http://purl.obolibrary.org/obo/CHEBI_36347) + + + +### attached to `http://purl.obolibrary.org/obo/RO_0002371` +#### Removed +- [attached to](http://purl.obolibrary.org/obo/RO_0002371) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [attached to](http://purl.obolibrary.org/obo/RO_0002371) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### auditory hair cell `http://purl.obolibrary.org/obo/CL_0000202` +#### Removed +- [auditory hair cell](http://purl.obolibrary.org/obo/CL_0000202) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000201" + + + +### axon synapses in `http://purl.obolibrary.org/obo/RO_0002102` +#### Removed +- [axon synapses in](http://purl.obolibrary.org/obo/RO_0002102) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall"@en + +- [axon synapses in](http://purl.obolibrary.org/obo/RO_0002102) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland" + +- [axon synapses in](http://purl.obolibrary.org/obo/RO_0002102) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland"@en + +#### Added +- [axon synapses in](http://purl.obolibrary.org/obo/RO_0002102) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + +- [axon synapses in](http://purl.obolibrary.org/obo/RO_0002102) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### azane `http://purl.obolibrary.org/obo/CHEBI_35107` +#### Removed +- [azane](http://purl.obolibrary.org/obo/CHEBI_35107) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35107" + +- [azane](http://purl.obolibrary.org/obo/CHEBI_35107) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "azanes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [azane](http://purl.obolibrary.org/obo/CHEBI_35107) [label](http://www.w3.org/2000/01/rdf-schema#label) "azane" + +- [azane](http://purl.obolibrary.org/obo/CHEBI_35107) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [azane](http://purl.obolibrary.org/obo/CHEBI_35107) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Saturated acyclic nitrogen hydrides having the general formula NnHn+2." + +- [azane](http://purl.obolibrary.org/obo/CHEBI_35107) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [azane](http://purl.obolibrary.org/obo/CHEBI_35107) + +- [azane](http://purl.obolibrary.org/obo/CHEBI_35107) SubClassOf [nitrogen hydride](http://purl.obolibrary.org/obo/CHEBI_35106) + + + +### azanide `http://purl.obolibrary.org/obo/CHEBI_29337` +#### Removed +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NH2(-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) [mass](http://purl.obolibrary.org/obo/chebi/mass) "16.02262" + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:29337" + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "azanide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "amide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) [formula](http://purl.obolibrary.org/obo/chebi/formula) "H2N" + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) [label](http://www.w3.org/2000/01/rdf-schema#label) "azanide" + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H][N-][H]" + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "16.01927" + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/H2N/h1H2/q-1" + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dihydridonitrate(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "HYGWNUKOUCZBND-UHFFFAOYSA-N" + +- Class: [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) SubClassOf [nitrogen hydride](http://purl.obolibrary.org/obo/CHEBI_35106) + +- [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) SubClassOf [monovalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79389) + + + +### azole `http://purl.obolibrary.org/obo/CHEBI_68452` +#### Removed +- [azole](http://purl.obolibrary.org/obo/CHEBI_68452) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Azole" + +- [azole](http://purl.obolibrary.org/obo/CHEBI_68452) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen." + +- [azole](http://purl.obolibrary.org/obo/CHEBI_68452) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [azole](http://purl.obolibrary.org/obo/CHEBI_68452) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [azole](http://purl.obolibrary.org/obo/CHEBI_68452) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:68452" + +- [azole](http://purl.obolibrary.org/obo/CHEBI_68452) [label](http://www.w3.org/2000/01/rdf-schema#label) "azole" + +- [azole](http://purl.obolibrary.org/obo/CHEBI_68452) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "azoles" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [azole](http://purl.obolibrary.org/obo/CHEBI_68452) + +- [azole](http://purl.obolibrary.org/obo/CHEBI_68452) SubClassOf [organonitrogen heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_38101) + +- [azole](http://purl.obolibrary.org/obo/CHEBI_68452) SubClassOf [monocyclic heteroarene](http://purl.obolibrary.org/obo/CHEBI_38179) + + + +### azole transmembrane transport `http://purl.obolibrary.org/obo/GO_0045117` +#### Removed +- [azole transmembrane transport](http://purl.obolibrary.org/obo/GO_0045117) [label](http://www.w3.org/2000/01/rdf-schema#label) "azole transmembrane transport" + +- [azole transmembrane transport](http://purl.obolibrary.org/obo/GO_0045117) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "azole transport" + +- [azole transmembrane transport](http://purl.obolibrary.org/obo/GO_0045117) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0045117" + +- [azole transmembrane transport](http://purl.obolibrary.org/obo/GO_0045117) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of azoles, heterocyclic compounds found in many biologically important substances, across a lipid bilayer, across a membrane." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:3527307206" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Azole" + +- [azole transmembrane transport](http://purl.obolibrary.org/obo/GO_0045117) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [azole transmembrane transport](http://purl.obolibrary.org/obo/GO_0045117) + +- [azole transmembrane transport](http://purl.obolibrary.org/obo/GO_0045117) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([results in transport across](http://purl.obolibrary.org/obo/RO_0002342) some [membrane](http://purl.obolibrary.org/obo/GO_0016020)) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [azole](http://purl.obolibrary.org/obo/CHEBI_68452)) + +- [azole transmembrane transport](http://purl.obolibrary.org/obo/GO_0045117) SubClassOf [transmembrane transport](http://purl.obolibrary.org/obo/GO_0055085) + +- [azole transmembrane transport](http://purl.obolibrary.org/obo/GO_0045117) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [azole](http://purl.obolibrary.org/obo/CHEBI_68452) + +- [azole transmembrane transport](http://purl.obolibrary.org/obo/GO_0045117) SubClassOf [organic substance transport](http://purl.obolibrary.org/obo/GO_0071702) + +- [azole transmembrane transport](http://purl.obolibrary.org/obo/GO_0045117) SubClassOf [nitrogen compound transport](http://purl.obolibrary.org/obo/GO_0071705) + + + +### azole transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_1901474` +#### Removed +- [azole transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901474) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "azole transporter activity" + +- [azole transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901474) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tb" + +- [azole transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901474) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the directed movement of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:3527307206" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Azole" + +- [azole transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901474) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0045118" + +- [azole transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901474) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901474" + +- [azole transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901474) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [azole transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901474) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-04T20:00:27Z" + +- [azole transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901474) [label](http://www.w3.org/2000/01/rdf-schema#label) "azole transmembrane transporter activity" + +- Class: [azole transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901474) + +- [azole transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901474) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [azole](http://purl.obolibrary.org/obo/CHEBI_68452)) + +- [azole transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901474) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [azole transmembrane transport](http://purl.obolibrary.org/obo/GO_0045117) + +- [azole transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901474) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + +- [azole transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901474) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [azole](http://purl.obolibrary.org/obo/CHEBI_68452) + + + +### bacterial metabolite `http://purl.obolibrary.org/obo/CHEBI_76969` +#### Removed +- [bacterial metabolite](http://purl.obolibrary.org/obo/CHEBI_76969) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [bacterial metabolite](http://purl.obolibrary.org/obo/CHEBI_76969) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:76969" + +- [bacterial metabolite](http://purl.obolibrary.org/obo/CHEBI_76969) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any prokaryotic metabolite produced during a metabolic reaction in bacteria." + +- [bacterial metabolite](http://purl.obolibrary.org/obo/CHEBI_76969) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:75760" + +- [bacterial metabolite](http://purl.obolibrary.org/obo/CHEBI_76969) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:76970" + +- [bacterial metabolite](http://purl.obolibrary.org/obo/CHEBI_76969) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [bacterial metabolite](http://purl.obolibrary.org/obo/CHEBI_76969) [label](http://www.w3.org/2000/01/rdf-schema#label) "bacterial metabolite" + +- Class: [bacterial metabolite](http://purl.obolibrary.org/obo/CHEBI_76969) + +- [bacterial metabolite](http://purl.obolibrary.org/obo/CHEBI_76969) SubClassOf [prokaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75787) + + + +### band form neutrophil `http://purl.obolibrary.org/obo/CL_0000560` +#### Removed +- [band form neutrophil](http://purl.obolibrary.org/obo/CL_0000560) EquivalentTo [mature neutrophil](http://purl.obolibrary.org/obo/CL_0000096) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [banded nucleus](http://purl.obolibrary.org/obo/CL_0017506)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [transcription factor PU.1](http://purl.obolibrary.org/obo/PR_000001944)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [protein c-Fos](http://purl.obolibrary.org/obo/PR_000007597)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement receptor type 1](http://purl.obolibrary.org/obo/PR_000001337)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [fMet-Leu-Phe receptor](http://purl.obolibrary.org/obo/PR_000001580)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [lactotransferrin](http://purl.obolibrary.org/obo/PR_000009978)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [myb proto-oncogene protein](http://purl.obolibrary.org/obo/PR_000010799)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-4](http://purl.obolibrary.org/obo/PR_000009129)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [myeloperoxidase](http://purl.obolibrary.org/obo/PR_000010543)) + +- [band form neutrophil](http://purl.obolibrary.org/obo/CL_0000560) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [myeloperoxidase](http://purl.obolibrary.org/obo/PR_000010543) + +- [band form neutrophil](http://purl.obolibrary.org/obo/CL_0000560) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [myb proto-oncogene protein](http://purl.obolibrary.org/obo/PR_000010799) + +- [band form neutrophil](http://purl.obolibrary.org/obo/CL_0000560) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [lactotransferrin](http://purl.obolibrary.org/obo/PR_000009978) + +- [band form neutrophil](http://purl.obolibrary.org/obo/CL_0000560) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-4](http://purl.obolibrary.org/obo/PR_000009129) + +#### Added +- [band form neutrophil](http://purl.obolibrary.org/obo/CL_0000560) EquivalentTo [mature neutrophil](http://purl.obolibrary.org/obo/CL_0000096) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [banded nucleus](http://purl.obolibrary.org/obo/CL_0017506)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [transcription factor PU.1](http://purl.obolibrary.org/obo/PR_000001944)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [protein c-Fos](http://purl.obolibrary.org/obo/PR_000007597)) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [lactotransferrin](http://purl.obolibrary.org/obo/PR_000009978)) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [myb proto-oncogene protein](http://purl.obolibrary.org/obo/PR_000010799)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-4](http://purl.obolibrary.org/obo/PR_000009129)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [myeloperoxidase](http://purl.obolibrary.org/obo/PR_000010543)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement receptor type 1](http://purl.obolibrary.org/obo/PR_000001337)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [fMet-Leu-Phe receptor](http://purl.obolibrary.org/obo/PR_000001580)) + +- [band form neutrophil](http://purl.obolibrary.org/obo/CL_0000560) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [myeloperoxidase](http://purl.obolibrary.org/obo/PR_000010543) + +- [band form neutrophil](http://purl.obolibrary.org/obo/CL_0000560) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-4](http://purl.obolibrary.org/obo/PR_000009129) + + +### baryon `http://purl.obolibrary.org/obo/CHEBI_36339` +#### Removed +- [baryon](http://purl.obolibrary.org/obo/CHEBI_36339) [label](http://www.w3.org/2000/01/rdf-schema#label) "baryon" + +- [baryon](http://purl.obolibrary.org/obo/CHEBI_36339) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy)." + +- [baryon](http://purl.obolibrary.org/obo/CHEBI_36339) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "baryons" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [baryon](http://purl.obolibrary.org/obo/CHEBI_36339) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [baryon](http://purl.obolibrary.org/obo/CHEBI_36339) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36339" + +- [baryon](http://purl.obolibrary.org/obo/CHEBI_36339) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [baryon](http://purl.obolibrary.org/obo/CHEBI_36339) + +- [baryon](http://purl.obolibrary.org/obo/CHEBI_36339) SubClassOf [fermion](http://purl.obolibrary.org/obo/CHEBI_36340) + +- [baryon](http://purl.obolibrary.org/obo/CHEBI_36339) SubClassOf [hadron](http://purl.obolibrary.org/obo/CHEBI_36344) + + + +### basal cell of epidermis `http://purl.obolibrary.org/obo/CL_0002187` +#### Removed +- [basal cell of epidermis](http://purl.obolibrary.org/obo/CL_0002187) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000439" + + + +### basal cell of epithelium of bronchus `http://purl.obolibrary.org/obo/CL_1000349` +#### Removed +- [basal cell of epithelium of bronchus](http://purl.obolibrary.org/obo/CL_1000349) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0002331" + + + +### basal cell of olfactory epithelium `http://purl.obolibrary.org/obo/CL_0002169` +#### Removed +- [basal cell of olfactory epithelium](http://purl.obolibrary.org/obo/CL_0002169) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000395" + + + +### basal cell of prostatic acinus `http://purl.obolibrary.org/obo/CL_0002234` +#### Removed +- [basal cell of prostatic acinus](http://purl.obolibrary.org/obo/CL_0002234) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000464" + + + +### basal epithelial cell of prostatic duct `http://purl.obolibrary.org/obo/CL_0002236` +#### Removed +- [basal epithelial cell of prostatic duct](http://purl.obolibrary.org/obo/CL_0002236) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000463" + + + +### base `http://purl.obolibrary.org/obo/CHEBI_22695` +#### Removed +- [base](http://purl.obolibrary.org/obo/CHEBI_22695) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Base2" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [base](http://purl.obolibrary.org/obo/CHEBI_22695) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:22695" + +- [base](http://purl.obolibrary.org/obo/CHEBI_22695) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "base" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [base](http://purl.obolibrary.org/obo/CHEBI_22695) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Base" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [base](http://purl.obolibrary.org/obo/CHEBI_22695) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [base](http://purl.obolibrary.org/obo/CHEBI_22695) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bases" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [base](http://purl.obolibrary.org/obo/CHEBI_22695) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [base](http://purl.obolibrary.org/obo/CHEBI_22695) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Nucleobase" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [base](http://purl.obolibrary.org/obo/CHEBI_22695) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "base" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [base](http://purl.obolibrary.org/obo/CHEBI_22695) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base)." + +- [base](http://purl.obolibrary.org/obo/CHEBI_22695) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00701" + +- [base](http://purl.obolibrary.org/obo/CHEBI_22695) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Basen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [base](http://purl.obolibrary.org/obo/CHEBI_22695) [label](http://www.w3.org/2000/01/rdf-schema#label) "base" + +- [base](http://purl.obolibrary.org/obo/CHEBI_22695) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Base1" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- Class: [base](http://purl.obolibrary.org/obo/CHEBI_22695) + +- [base](http://purl.obolibrary.org/obo/CHEBI_22695) SubClassOf [chemical role](http://purl.obolibrary.org/obo/CHEBI_51086) + + + +### basic amino acid transmembrane transport `http://purl.obolibrary.org/obo/GO_1990822` + +#### Added +- [basic amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1990822) [label](http://www.w3.org/2000/01/rdf-schema#label) "basic amino acid transmembrane transport" + +- [basic amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1990822) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2015-08-19T07:47:00Z" + +- [basic amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1990822) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of basic amino acids from one side of a membrane to the other." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:vw" + +- [basic amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1990822) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "vw" + +- [basic amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1990822) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1990822" + +- [basic amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1990822) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [basic amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1990822) + +- [basic amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1990822) EquivalentTo [basic amino acid transport](http://purl.obolibrary.org/obo/GO_0015802) and ([results in transport across](http://purl.obolibrary.org/obo/RO_0002342) some [membrane](http://purl.obolibrary.org/obo/GO_0016020)) + +- [basic amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1990822) SubClassOf [amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_0003333) + +- [basic amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1990822) SubClassOf [basic amino acid transport](http://purl.obolibrary.org/obo/GO_0015802) + + +### basic amino acid transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015174` + +#### Added +- [basic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015174) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015174" + +- [basic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015174) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cationic amino acid transmembrane transporter activity" + +- [basic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015174) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0005286" + +- [basic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015174) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-8932851" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol" + +- [basic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015174) [label](http://www.w3.org/2000/01/rdf-schema#label) "basic amino acid transmembrane transporter activity" + +- [basic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015174) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have side chains with a positive charge at pH 7.3." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0815340729" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_transport" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [basic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015174) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-8959781" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix" + +- [basic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015174) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0015326" + +- [basic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015174) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "basic amino acid transporter activity" + +- [basic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015174) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [basic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015174) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "basic amino acid permease activity" + +- Class: [basic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015174) + +- [basic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015174) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [basic amino acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1990822) + +- [basic amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015174) SubClassOf [amino acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015171) + + +### basic amino acid transport `http://purl.obolibrary.org/obo/GO_0015802` + +#### Added +- [basic amino acid transport](http://purl.obolibrary.org/obo/GO_0015802) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [basic amino acid transport](http://purl.obolibrary.org/obo/GO_0015802) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [basic amino acid transport](http://purl.obolibrary.org/obo/GO_0015802) [label](http://www.w3.org/2000/01/rdf-schema#label) "basic amino acid transport" + +- [basic amino acid transport](http://purl.obolibrary.org/obo/GO_0015802) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015802" + +- Class: [basic amino acid transport](http://purl.obolibrary.org/obo/GO_0015802) + +- [basic amino acid transport](http://purl.obolibrary.org/obo/GO_0015802) SubClassOf [amino acid transport](http://purl.obolibrary.org/obo/GO_0006865) + + +### basophil mast progenitor cell `http://purl.obolibrary.org/obo/CL_0002028` +#### Removed +- [basophil mast progenitor cell](http://purl.obolibrary.org/obo/CL_0002028) EquivalentTo [myeloid lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0000839) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [erythroid transcription factor](http://purl.obolibrary.org/obo/PR_000007857)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [endothelial transcription factor GATA-2](http://purl.obolibrary.org/obo/PR_000007858)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-5 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001867)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [basophil differentiation](http://purl.obolibrary.org/obo/GO_0030221)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [mast cell differentiation](http://purl.obolibrary.org/obo/GO_0060374)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [transmembrane emp24 domain-containing protein 1](http://purl.obolibrary.org/obo/PR_000016401)) + +- [basophil mast progenitor cell](http://purl.obolibrary.org/obo/CL_0002028) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431) + +- [basophil mast progenitor cell](http://purl.obolibrary.org/obo/CL_0002028) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [transmembrane emp24 domain-containing protein 1](http://purl.obolibrary.org/obo/PR_000016401) + +#### Added +- [basophil mast progenitor cell](http://purl.obolibrary.org/obo/CL_0002028) EquivalentTo [myeloid lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0000839) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [erythroid transcription factor](http://purl.obolibrary.org/obo/PR_000007857)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [endothelial transcription factor GATA-2](http://purl.obolibrary.org/obo/PR_000007858)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [transmembrane emp24 domain-containing protein 1](http://purl.obolibrary.org/obo/PR_000016401)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-5 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001867)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [basophil differentiation](http://purl.obolibrary.org/obo/GO_0030221)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [mast cell differentiation](http://purl.obolibrary.org/obo/GO_0060374)) + +- [basophil mast progenitor cell](http://purl.obolibrary.org/obo/CL_0002028) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [transmembrane emp24 domain-containing protein 1](http://purl.obolibrary.org/obo/PR_000016401) + +- [basophil mast progenitor cell](http://purl.obolibrary.org/obo/CL_0002028) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431) + + +### basophil progenitor cell `http://purl.obolibrary.org/obo/CL_0000613` +#### Removed +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) EquivalentTo [granulocytopoietic cell](http://purl.obolibrary.org/obo/CL_0002191) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [erythroid transcription factor](http://purl.obolibrary.org/obo/PR_000007857)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [endothelial transcription factor GATA-2](http://purl.obolibrary.org/obo/PR_000007858)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [basophil differentiation](http://purl.obolibrary.org/obo/GO_0030221)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [transmembrane emp24 domain-containing protein 1](http://purl.obolibrary.org/obo/PR_000016401)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +#### Added +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) EquivalentTo [granulocytopoietic cell](http://purl.obolibrary.org/obo/CL_0002191) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [erythroid transcription factor](http://purl.obolibrary.org/obo/PR_000007857)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [endothelial transcription factor GATA-2](http://purl.obolibrary.org/obo/PR_000007858)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [basophil differentiation](http://purl.obolibrary.org/obo/GO_0030221)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [transmembrane emp24 domain-containing protein 1](http://purl.obolibrary.org/obo/PR_000016401)) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [basophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000613) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + + +### basophilic myelocyte `http://purl.obolibrary.org/obo/CL_0000614` +#### Removed +- [basophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000614) EquivalentTo [immature basophil](http://purl.obolibrary.org/obo/CL_0000768) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-(1,3)-fucosyltransferase 4](http://purl.obolibrary.org/obo/PR_000001456)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD33 molecule](http://purl.obolibrary.org/obo/PR_000001892)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [aminopeptidase N](http://purl.obolibrary.org/obo/PR_000002031)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [nucleolus](http://purl.obolibrary.org/obo/GO_0005730)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [tertiary granule](http://purl.obolibrary.org/obo/GO_0070820)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) + +- [basophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000614) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483) + +- [basophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000614) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [tertiary granule](http://purl.obolibrary.org/obo/GO_0070820) + +- [basophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000614) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [nucleolus](http://purl.obolibrary.org/obo/GO_0005730) + +#### Added +- [basophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000614) EquivalentTo [immature basophil](http://purl.obolibrary.org/obo/CL_0000768) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582)) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [nucleolus](http://purl.obolibrary.org/obo/GO_0005730)) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [tertiary granule](http://purl.obolibrary.org/obo/GO_0070820)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-(1,3)-fucosyltransferase 4](http://purl.obolibrary.org/obo/PR_000001456)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD33 molecule](http://purl.obolibrary.org/obo/PR_000001892)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [aminopeptidase N](http://purl.obolibrary.org/obo/PR_000002031)) + +- [basophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000614) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483) + +- [basophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000614) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [nucleolus](http://purl.obolibrary.org/obo/GO_0005730) + +- [basophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000614) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [tertiary granule](http://purl.obolibrary.org/obo/GO_0070820) + + +### benzenediols `http://purl.obolibrary.org/obo/CHEBI_33570` +#### Removed +- [benzenediols](http://purl.obolibrary.org/obo/CHEBI_33570) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22711" + +- [benzenediols](http://purl.obolibrary.org/obo/CHEBI_33570) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22705" + +- [benzenediols](http://purl.obolibrary.org/obo/CHEBI_33570) [label](http://www.w3.org/2000/01/rdf-schema#label) "benzenediols" + +- [benzenediols](http://purl.obolibrary.org/obo/CHEBI_33570) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [benzenediols](http://purl.obolibrary.org/obo/CHEBI_33570) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [benzenediols](http://purl.obolibrary.org/obo/CHEBI_33570) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33570" + +- Class: [benzenediols](http://purl.obolibrary.org/obo/CHEBI_33570) + +- [benzenediols](http://purl.obolibrary.org/obo/CHEBI_33570) SubClassOf [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) + + + +### benzopyrrole `http://purl.obolibrary.org/obo/CHEBI_22728` +#### Removed +- [benzopyrrole](http://purl.obolibrary.org/obo/CHEBI_22728) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "benzopyrroles" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [benzopyrrole](http://purl.obolibrary.org/obo/CHEBI_22728) [label](http://www.w3.org/2000/01/rdf-schema#label) "benzopyrrole" + +- [benzopyrrole](http://purl.obolibrary.org/obo/CHEBI_22728) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:22728" + +- [benzopyrrole](http://purl.obolibrary.org/obo/CHEBI_22728) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [benzopyrrole](http://purl.obolibrary.org/obo/CHEBI_22728) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [benzopyrrole](http://purl.obolibrary.org/obo/CHEBI_22728) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "benzopyrroles" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [benzopyrrole](http://purl.obolibrary.org/obo/CHEBI_22728) + +- [benzopyrrole](http://purl.obolibrary.org/obo/CHEBI_22728) SubClassOf [organic heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_27171) + +- [benzopyrrole](http://purl.obolibrary.org/obo/CHEBI_22728) SubClassOf [organonitrogen heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_38101) + +- [benzopyrrole](http://purl.obolibrary.org/obo/CHEBI_22728) SubClassOf [polycyclic heteroarene](http://purl.obolibrary.org/obo/CHEBI_38180) + + + +### beta-adrenergic agonist `http://purl.obolibrary.org/obo/CHEBI_35522` +#### Removed +- [beta-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35522) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "beta-adrenergic agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [beta-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35522) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35522" + +- [beta-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35522) [label](http://www.w3.org/2000/01/rdf-schema#label) "beta-adrenergic agonist" + +- [beta-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35522) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "beta-adrenoceptor agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPHAR" + +- [beta-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35522) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An agent that selectively binds to and activates beta-adrenergic receptors." + +- [beta-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35522) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "beta-adrenergic receptor agonist" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [beta-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35522) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [beta-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35522) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [beta-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35522) + +- [beta-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35522) SubClassOf [adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_37886) + +- [beta-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35522) SubClassOf [beta-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48540) + + + +### beta-adrenergic drug `http://purl.obolibrary.org/obo/CHEBI_48540` +#### Removed +- [beta-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48540) [label](http://www.w3.org/2000/01/rdf-schema#label) "beta-adrenergic drug" + +- [beta-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48540) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [beta-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48540) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [beta-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48540) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any of the drugs that act on beta-adrenergic receptors." + +- [beta-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48540) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:48540" + +- [beta-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48540) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "beta-adrenergic drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [beta-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48540) + +- [beta-adrenergic drug](http://purl.obolibrary.org/obo/CHEBI_48540) SubClassOf [adrenergic agent](http://purl.obolibrary.org/obo/CHEBI_37962) + + + +### bicarbonate binding `http://purl.obolibrary.org/obo/GO_0071890` +#### Removed +- [bicarbonate binding](http://purl.obolibrary.org/obo/GO_0071890) SubClassOf [anion binding](http://purl.obolibrary.org/obo/GO_0043168) + +#### Added +- [bicarbonate binding](http://purl.obolibrary.org/obo/GO_0071890) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### bicarbonate transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015106` +#### Removed +- [bicarbonate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015106) SubClassOf [organic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008514) + +#### Added +- [bicarbonate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015106) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + +### bicarbonate transport `http://purl.obolibrary.org/obo/GO_0015701` +#### Removed +- [bicarbonate transport](http://purl.obolibrary.org/obo/GO_0015701) SubClassOf [organic anion transport](http://purl.obolibrary.org/obo/GO_0015711) + +#### Added +- [bicarbonate transport](http://purl.obolibrary.org/obo/GO_0015701) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### bicyclic compound `http://purl.obolibrary.org/obo/CHEBI_33636` +#### Removed +- [bicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33636) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bicyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33636) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33636" + +- [bicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33636) [label](http://www.w3.org/2000/01/rdf-schema#label) "bicyclic compound" + +- [bicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33636) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [bicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33636) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecule that features two fused rings." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [bicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33636) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [bicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33636) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bicyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- Class: [bicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33636) + +- [bicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33636) SubClassOf [cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33595) + + + +### biladienes `http://purl.obolibrary.org/obo/CHEBI_36735` +#### Removed +- [biladienes](http://purl.obolibrary.org/obo/CHEBI_36735) [label](http://www.w3.org/2000/01/rdf-schema#label) "biladienes" + +- [biladienes](http://purl.obolibrary.org/obo/CHEBI_36735) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Compounds based on a biladiene skeleton." + +- [biladienes](http://purl.obolibrary.org/obo/CHEBI_36735) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [biladienes](http://purl.obolibrary.org/obo/CHEBI_36735) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36735" + +- [biladienes](http://purl.obolibrary.org/obo/CHEBI_36735) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [biladienes](http://purl.obolibrary.org/obo/CHEBI_36735) + +- [biladienes](http://purl.obolibrary.org/obo/CHEBI_36735) SubClassOf [linear tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_25046) + + + +### bile acid `http://purl.obolibrary.org/obo/CHEBI_3098` +#### Removed +- [bile acid](http://purl.obolibrary.org/obo/CHEBI_3098) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "5beta-bile acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bile acid](http://purl.obolibrary.org/obo/CHEBI_3098) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Gallensaeuren" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bile acid](http://purl.obolibrary.org/obo/CHEBI_3098) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "5beta-bile acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bile acid](http://purl.obolibrary.org/obo/CHEBI_3098) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Bile salt" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [bile acid](http://purl.obolibrary.org/obo/CHEBI_3098) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Gallensaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bile acid](http://purl.obolibrary.org/obo/CHEBI_3098) [label](http://www.w3.org/2000/01/rdf-schema#label) "bile acid" + +- [bile acid](http://purl.obolibrary.org/obo/CHEBI_3098) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any member of a group of hydroxy-5beta-cholanic acids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration." + +- [bile acid](http://purl.obolibrary.org/obo/CHEBI_3098) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:3098" + +- [bile acid](http://purl.obolibrary.org/obo/CHEBI_3098) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Bile acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [bile acid](http://purl.obolibrary.org/obo/CHEBI_3098) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bile acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bile acid](http://purl.obolibrary.org/obo/CHEBI_3098) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [bile acid](http://purl.obolibrary.org/obo/CHEBI_3098) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01558" + +- [bile acid](http://purl.obolibrary.org/obo/CHEBI_3098) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [bile acid](http://purl.obolibrary.org/obo/CHEBI_3098) SubClassOf [bile acids](http://purl.obolibrary.org/obo/CHEBI_138366) + +- [bile acid](http://purl.obolibrary.org/obo/CHEBI_3098) SubClassOf [hydroxy-5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_24663) + + + +### bile acid and bile salt transport `http://purl.obolibrary.org/obo/GO_0015721` +#### Removed +- [bile acid and bile salt transport](http://purl.obolibrary.org/obo/GO_0015721) SubClassOf [organic acid transport](http://purl.obolibrary.org/obo/GO_0015849) + + + +### bile acid anion `http://purl.obolibrary.org/obo/CHEBI_36235` +#### Removed +- [bile acid anion](http://purl.obolibrary.org/obo/CHEBI_36235) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [bile acid anion](http://purl.obolibrary.org/obo/CHEBI_36235) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [bile acid anion](http://purl.obolibrary.org/obo/CHEBI_36235) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36235" + +- [bile acid anion](http://purl.obolibrary.org/obo/CHEBI_36235) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bile acid anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bile acid anion](http://purl.obolibrary.org/obo/CHEBI_36235) [label](http://www.w3.org/2000/01/rdf-schema#label) "bile acid anion" + +- [bile acid anion](http://purl.obolibrary.org/obo/CHEBI_36235) SubClassOf [steroid acid anion](http://purl.obolibrary.org/obo/CHEBI_50160) + +- [bile acid anion](http://purl.obolibrary.org/obo/CHEBI_36235) SubClassOf [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) + + + +### bile acid binding `http://purl.obolibrary.org/obo/GO_0032052` +#### Removed +- [bile acid binding](http://purl.obolibrary.org/obo/GO_0032052) SubClassOf [monocarboxylic acid binding](http://purl.obolibrary.org/obo/GO_0033293) + +#### Added +- [bile acid binding](http://purl.obolibrary.org/obo/GO_0032052) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### bile acid catabolic process `http://purl.obolibrary.org/obo/GO_0030573` +#### Removed +- [bile acid catabolic process](http://purl.obolibrary.org/obo/GO_0030573) SubClassOf [monocarboxylic acid catabolic process](http://purl.obolibrary.org/obo/GO_0072329) + +#### Added +- [bile acid catabolic process](http://purl.obolibrary.org/obo/GO_0030573) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### bile acid salt `http://purl.obolibrary.org/obo/CHEBI_36277` +#### Removed +- [bile acid salt](http://purl.obolibrary.org/obo/CHEBI_36277) [label](http://www.w3.org/2000/01/rdf-schema#label) "bile acid salt" + +- [bile acid salt](http://purl.obolibrary.org/obo/CHEBI_36277) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [bile acid salt](http://purl.obolibrary.org/obo/CHEBI_36277) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36277" + +- [bile acid salt](http://purl.obolibrary.org/obo/CHEBI_36277) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [bile acid salt](http://purl.obolibrary.org/obo/CHEBI_36277) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bile acid salts" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bile acid salt](http://purl.obolibrary.org/obo/CHEBI_36277) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A salt of a bile acid." + +- [bile acid salt](http://purl.obolibrary.org/obo/CHEBI_36277) SubClassOf [cholanoid](http://purl.obolibrary.org/obo/CHEBI_36078) + +- [bile acid salt](http://purl.obolibrary.org/obo/CHEBI_36277) SubClassOf [organic salt](http://purl.obolibrary.org/obo/CHEBI_24868) + + + +### bile acid secretion `http://purl.obolibrary.org/obo/GO_0032782` +#### Removed +- [bile acid secretion](http://purl.obolibrary.org/obo/GO_0032782) SubClassOf [monocarboxylic acid transport](http://purl.obolibrary.org/obo/GO_0015718) + + + +### bile acid transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015125` +#### Removed +- [bile acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015125) SubClassOf [lipid transporter activity](http://purl.obolibrary.org/obo/GO_0005319) + +- [bile acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015125) SubClassOf [monocarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008028) + +- [bile acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015125) SubClassOf [organic hydroxy compound transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901618) + +#### Added +- [bile acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015125) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + +### bile acids `http://purl.obolibrary.org/obo/CHEBI_138366` +#### Removed +- [bile acids](http://purl.obolibrary.org/obo/CHEBI_138366) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [bile acids](http://purl.obolibrary.org/obo/CHEBI_138366) [label](http://www.w3.org/2000/01/rdf-schema#label) "bile acids" + +- [bile acids](http://purl.obolibrary.org/obo/CHEBI_138366) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:138366" + +- [bile acids](http://purl.obolibrary.org/obo/CHEBI_138366) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [bile acids](http://purl.obolibrary.org/obo/CHEBI_138366) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any member of a group of hydroxy steroids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration, while in lower vertebrates, some bile acids, known as allo-bile acids, have 5alpha-configuration." + +- Class: [bile acids](http://purl.obolibrary.org/obo/CHEBI_138366) + +- [bile acids](http://purl.obolibrary.org/obo/CHEBI_138366) SubClassOf [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) + +- [bile acids](http://purl.obolibrary.org/obo/CHEBI_138366) SubClassOf [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) + +- [bile acids](http://purl.obolibrary.org/obo/CHEBI_138366) SubClassOf [cholanoid](http://purl.obolibrary.org/obo/CHEBI_36078) + + + +### bile salt `http://purl.obolibrary.org/obo/CHEBI_22868` +#### Removed +- [bile salt](http://purl.obolibrary.org/obo/CHEBI_22868) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [bile salt](http://purl.obolibrary.org/obo/CHEBI_22868) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Bile acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [bile salt](http://purl.obolibrary.org/obo/CHEBI_22868) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A sodium salt of the conjugate of any bile acid with either glycine or taurine." + +- [bile salt](http://purl.obolibrary.org/obo/CHEBI_22868) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bile salts" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bile salt](http://purl.obolibrary.org/obo/CHEBI_22868) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01558" + +- [bile salt](http://purl.obolibrary.org/obo/CHEBI_22868) [label](http://www.w3.org/2000/01/rdf-schema#label) "bile salt" + +- [bile salt](http://purl.obolibrary.org/obo/CHEBI_22868) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:22868" + +- [bile salt](http://purl.obolibrary.org/obo/CHEBI_22868) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [bile salt](http://purl.obolibrary.org/obo/CHEBI_22868) SubClassOf [organic sodium salt](http://purl.obolibrary.org/obo/CHEBI_38700) + +- [bile salt](http://purl.obolibrary.org/obo/CHEBI_22868) SubClassOf [cholanoid](http://purl.obolibrary.org/obo/CHEBI_36078) + + + +### bilirubin IXalpha `http://purl.obolibrary.org/obo/CHEBI_16990` +#### Removed +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23763371" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bilirubin(Z,Z)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:BLR" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [label](http://www.w3.org/2000/01/rdf-schema#label) "bilirubin IXalpha" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:8605219" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18442622" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinylbiline-8,12-dipropionic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Bilirubin" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "CC1=C(C=C)\C(NC1=O)=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(CCC(O)=O)C(C)=C(N2)\C=C2/NC(=O)C(C=C)=C2C)N1" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12799017" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22870" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:635-65-4" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00486" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:74376" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bilirubin-IXalpha" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-3,18-divinylbiladiene-ac-1,19(21H,24H)-dione" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "JCBN" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13898" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C33H36N4O6" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30224965" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "BPYKTIZUTYGOLE-IFADSCNNSA-N" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:411033" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:16990" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Bilirubin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "3,18-diethenyl-2,7,13,17-tetramethyl-1,19-dioxo-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:74376" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [mass](http://purl.obolibrary.org/obo/chebi/mass) "584.673" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000054" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A member of the class of biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin." + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:3099" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "bilirubin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23768684" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9587403" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "584.26348" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:635-65-4" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:BILIRUBIN" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00029828" + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [antioxidant](http://purl.obolibrary.org/obo/CHEBI_22586) + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [24G7 epitope](http://purl.obolibrary.org/obo/CHEBI_142163) + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) SubClassOf [biladienes](http://purl.obolibrary.org/obo/CHEBI_36735) + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) SubClassOf [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) + +- [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) + + + +### bilirubin transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015127` +#### Removed +- [bilirubin transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015127) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-5679031" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region" + +- [bilirubin transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015127) [label](http://www.w3.org/2000/01/rdf-schema#label) "bilirubin transmembrane transporter activity" + +- [bilirubin transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015127) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [bilirubin transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015127) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-9661417" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region" + +- [bilirubin transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015127) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198547684" + +- [bilirubin transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015127) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-5679041" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "ABCC2 transports BMG,BDG from cytosol to extracellular region" + +- [bilirubin transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015127) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015127" + +- Class: [bilirubin transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015127) + +- [bilirubin transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015127) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977)) + +- [bilirubin transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015127) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [bilirubin transport](http://purl.obolibrary.org/obo/GO_0015723) + +- [bilirubin transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015127) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) + +- [bilirubin transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015127) SubClassOf [carboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046943) + + + +### bilirubin transport `http://purl.obolibrary.org/obo/GO_0015723` +#### Removed +- [bilirubin transport](http://purl.obolibrary.org/obo/GO_0015723) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015723" + +- [bilirubin transport](http://purl.obolibrary.org/obo/GO_0015723) [label](http://www.w3.org/2000/01/rdf-schema#label) "bilirubin transport" + +- [bilirubin transport](http://purl.obolibrary.org/obo/GO_0015723) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [bilirubin transport](http://purl.obolibrary.org/obo/GO_0015723) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [bilirubin transport](http://purl.obolibrary.org/obo/GO_0015723) + +- [bilirubin transport](http://purl.obolibrary.org/obo/GO_0015723) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977)) + +- [bilirubin transport](http://purl.obolibrary.org/obo/GO_0015723) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) + +- [bilirubin transport](http://purl.obolibrary.org/obo/GO_0015723) SubClassOf [dicarboxylic acid transport](http://purl.obolibrary.org/obo/GO_0006835) + + + +### bilirubin(2-) `http://purl.obolibrary.org/obo/CHEBI_57977` +#### Removed +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) [mass](http://purl.obolibrary.org/obo/chebi/mass) "582.64630" + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A dicarboxylic acid dianion obtained by deprotonation of the two carboxy groups of bilirubin; major species at pH 7.3." + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:57977" + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:4083310" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "CC1=C(C=C)\C(NC1=O)=C\c1[nH]c(Cc2[nH]c(\C=C3NC(=O)C(C=C)=C/3C)c(C)c2CCC([O-])=O)c(CCC([O-])=O)c1C" + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bilirubin dianion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-2" + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/p-2/b26-13-,27-14-" + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "BPYKTIZUTYGOLE-IFADSCNNSA-L" + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bilirubin IXalpha" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "582.24893" + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) [label](http://www.w3.org/2000/01/rdf-schema#label) "bilirubin(2-)" + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C33H34N4O6" + +- Class: [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [bilirubin IXalpha](http://purl.obolibrary.org/obo/CHEBI_16990) + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) SubClassOf [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) + +- [bilirubin(2-)](http://purl.obolibrary.org/obo/CHEBI_57977) SubClassOf [linear tetrapyrrole anion](http://purl.obolibrary.org/obo/CHEBI_59252) + + + +### biochemical role `http://purl.obolibrary.org/obo/CHEBI_52206` +#### Removed +- [biochemical role](http://purl.obolibrary.org/obo/CHEBI_52206) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [biochemical role](http://purl.obolibrary.org/obo/CHEBI_52206) [label](http://www.w3.org/2000/01/rdf-schema#label) "biochemical role" + +- [biochemical role](http://purl.obolibrary.org/obo/CHEBI_52206) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A biological role played by the molecular entity or part thereof within a biochemical context." + +- [biochemical role](http://purl.obolibrary.org/obo/CHEBI_52206) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:52206" + +- [biochemical role](http://purl.obolibrary.org/obo/CHEBI_52206) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [biochemical role](http://purl.obolibrary.org/obo/CHEBI_52206) + +- [biochemical role](http://purl.obolibrary.org/obo/CHEBI_52206) SubClassOf [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) + + + +### biological role `http://purl.obolibrary.org/obo/CHEBI_24432` +#### Removed +- [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24432" + +- [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "biological function" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A role played by the molecular entity or part thereof within a biological context." + +- [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) [label](http://www.w3.org/2000/01/rdf-schema#label) "biological role" + +- [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) + +- [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) SubClassOf [role](http://purl.obolibrary.org/obo/BFO_0000023) + +- [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) SubClassOf [role](http://purl.obolibrary.org/obo/CHEBI_50906) + + + +### biological_process `http://purl.obolibrary.org/obo/GO_0008150` +#### Removed +- [biological_process](http://purl.obolibrary.org/obo/GO_0008150) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pdt" + +#### Added +- [biological_process](http://purl.obolibrary.org/obo/GO_0008150) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24968"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [biological_process](http://purl.obolibrary.org/obo/GO_0008150) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pdt" + + +### biomacromolecule `http://purl.obolibrary.org/obo/CHEBI_33694` +#### Removed +- [biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33694) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A macromolecule formed by a living organism." + +- [biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33694) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33694" + +- [biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33694) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Biopolymere" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33694) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33694) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "biomacromolecules" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33694) [label](http://www.w3.org/2000/01/rdf-schema#label) "biomacromolecule" + +- [biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33694) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "biopolymer" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33694) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "biopolymers" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33694) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33694) SubClassOf [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) + +- [biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33694) SubClassOf [macromolecule](http://purl.obolibrary.org/obo/CHEBI_33839) + + + +### biomechanically related to `http://purl.obolibrary.org/obo/RO_0002567` +#### Removed +- [biomechanically related to](http://purl.obolibrary.org/obo/RO_0002567) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [biomechanically related to](http://purl.obolibrary.org/obo/RO_0002567) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### blood cell `http://purl.obolibrary.org/obo/CL_0000081` +#### Removed +- [blood cell](http://purl.obolibrary.org/obo/CL_0000081) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### blood island `http://purl.obolibrary.org/obo/UBERON_0003061` +#### Removed +- [blood island](http://purl.obolibrary.org/obo/UBERON_0003061) SubClassOf [contains process](http://purl.obolibrary.org/obo/BFO_0000067) some [hemopoiesis](http://purl.obolibrary.org/obo/GO_0030097) + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ISBN:0073040584" + +- [blood island](http://purl.obolibrary.org/obo/UBERON_0003061) SubClassOf [contains process](http://purl.obolibrary.org/obo/BFO_0000067) some [angiogenesis](http://purl.obolibrary.org/obo/GO_0001525) + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ISBN:0073040584" + + + +### blood vessel `http://purl.obolibrary.org/obo/UBERON_0001981` + +#### Added +- [blood vessel](http://purl.obolibrary.org/obo/UBERON_0001981) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [blood vessel](http://purl.obolibrary.org/obo/UBERON_0001981) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + +### bone cell `http://purl.obolibrary.org/obo/CL_0001035` +#### Removed +- [bone cell](http://purl.obolibrary.org/obo/CL_0001035) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### bone density conservation agent `http://purl.obolibrary.org/obo/CHEBI_50646` +#### Removed +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:72497" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Osteoporosis" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bone density conservation agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antiosteoporotics" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-osteoporotics" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50646" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bone density conservation drug" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-osteoporotic agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-osteoporotic drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis." + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-osteoporotic drug" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-osteopenia drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antiosteoporotic" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-osteoporosis drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-osteoporosis agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-osteoporosis agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-osteoporosis drug" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-osteopenia drug" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bone density conservation drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [label](http://www.w3.org/2000/01/rdf-schema#label) "bone density conservation agent" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-osteoporotic" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-osteopenia agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-osteopenia agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-osteoporotic agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) + +- [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) SubClassOf [drug](http://purl.obolibrary.org/obo/CHEBI_23888) + + + +### bone marrow macrophage `http://purl.obolibrary.org/obo/CL_0002476` +#### Removed +- [bone marrow macrophage](http://purl.obolibrary.org/obo/CL_0002476) EquivalentTo [tissue-resident macrophage](http://purl.obolibrary.org/obo/CL_0000864) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrophage colony-stimulating factor 1 receptor](http://purl.obolibrary.org/obo/PR_000002062)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980)) + +- [bone marrow macrophage](http://purl.obolibrary.org/obo/CL_0002476) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [bone marrow macrophage](http://purl.obolibrary.org/obo/CL_0002476) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980) + +- [bone marrow macrophage](http://purl.obolibrary.org/obo/CL_0002476) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014) + +#### Added +- [bone marrow macrophage](http://purl.obolibrary.org/obo/CL_0002476) EquivalentTo [tissue-resident macrophage](http://purl.obolibrary.org/obo/CL_0000864) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrophage colony-stimulating factor 1 receptor](http://purl.obolibrary.org/obo/PR_000002062)) + +- [bone marrow macrophage](http://purl.obolibrary.org/obo/CL_0002476) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014) + +- [bone marrow macrophage](http://purl.obolibrary.org/obo/CL_0002476) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [bone marrow macrophage](http://purl.obolibrary.org/obo/CL_0002476) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980) + + +### boson `http://purl.obolibrary.org/obo/CHEBI_36341` +#### Removed +- [boson](http://purl.obolibrary.org/obo/CHEBI_36341) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose." + +- [boson](http://purl.obolibrary.org/obo/CHEBI_36341) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bosons" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [boson](http://purl.obolibrary.org/obo/CHEBI_36341) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [boson](http://purl.obolibrary.org/obo/CHEBI_36341) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [boson](http://purl.obolibrary.org/obo/CHEBI_36341) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36341" + +- [boson](http://purl.obolibrary.org/obo/CHEBI_36341) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "boson" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [boson](http://purl.obolibrary.org/obo/CHEBI_36341) [label](http://www.w3.org/2000/01/rdf-schema#label) "boson" + +- Class: [boson](http://purl.obolibrary.org/obo/CHEBI_36341) + +- [boson](http://purl.obolibrary.org/obo/CHEBI_36341) SubClassOf [subatomic particle](http://purl.obolibrary.org/obo/CHEBI_36342) + + + +### bounding layer of `http://purl.obolibrary.org/obo/RO_0002007` +#### Removed +- [bounding layer of](http://purl.obolibrary.org/obo/RO_0002007) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland" + +#### Added +- [bounding layer of](http://purl.obolibrary.org/obo/RO_0002007) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + + +### brain vascular cell `http://purl.obolibrary.org/obo/CL_4023072` +#### Removed +- [brain vascular cell](http://purl.obolibrary.org/obo/CL_4023072) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### branching part of `http://purl.obolibrary.org/obo/RO_0002380` +#### Removed +- [branching part of](http://purl.obolibrary.org/obo/RO_0002380) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [branching part of](http://purl.obolibrary.org/obo/RO_0002380) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### bronchiolar smooth muscle cell `http://purl.obolibrary.org/obo/CL_4033017` + +#### Added +- [bronchiolar smooth muscle cell](http://purl.obolibrary.org/obo/CL_4033017) [label](http://www.w3.org/2000/01/rdf-schema#label) "bronchiolar smooth muscle cell" + +- [bronchiolar smooth muscle cell](http://purl.obolibrary.org/obo/CL_4033017) [date](http://purl.org/dc/terms/date) "2023-03-16T09:38:17Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [bronchiolar smooth muscle cell](http://purl.obolibrary.org/obo/CL_4033017) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-9185-3994](https://orcid.org/0000-0002-9185-3994) + +- [bronchiolar smooth muscle cell](http://purl.obolibrary.org/obo/CL_4033017) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A smooth muscle cell that is part of a bronchiole." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15347627" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:9781260462982" + +- [bronchiolar smooth muscle cell](http://purl.obolibrary.org/obo/CL_4033017) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- Class: [bronchiolar smooth muscle cell](http://purl.obolibrary.org/obo/CL_4033017) + +- [bronchiolar smooth muscle cell](http://purl.obolibrary.org/obo/CL_4033017) EquivalentTo [smooth muscle cell](http://purl.obolibrary.org/obo/CL_0000192) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [bronchiole](http://purl.obolibrary.org/obo/UBERON_0002186)) + +- [bronchiolar smooth muscle cell](http://purl.obolibrary.org/obo/CL_4033017) SubClassOf [tracheobronchial smooth muscle cell](http://purl.obolibrary.org/obo/CL_0019019) + +- [bronchiolar smooth muscle cell](http://purl.obolibrary.org/obo/CL_4033017) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [bronchiole](http://purl.obolibrary.org/obo/UBERON_0002186) + + +### bronchodilator agent `http://purl.obolibrary.org/obo/CHEBI_35523` +#### Removed +- [bronchodilator agent](http://purl.obolibrary.org/obo/CHEBI_35523) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An agent that causes an increase in the expansion of a bronchus or bronchial tubes." + +- [bronchodilator agent](http://purl.obolibrary.org/obo/CHEBI_35523) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bronchodilator agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bronchodilator agent](http://purl.obolibrary.org/obo/CHEBI_35523) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bronchodilator" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bronchodilator agent](http://purl.obolibrary.org/obo/CHEBI_35523) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [bronchodilator agent](http://purl.obolibrary.org/obo/CHEBI_35523) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "broncholytic agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [bronchodilator agent](http://purl.obolibrary.org/obo/CHEBI_35523) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35523" + +- [bronchodilator agent](http://purl.obolibrary.org/obo/CHEBI_35523) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [bronchodilator agent](http://purl.obolibrary.org/obo/CHEBI_35523) [label](http://www.w3.org/2000/01/rdf-schema#label) "bronchodilator agent" + +- Class: [bronchodilator agent](http://purl.obolibrary.org/obo/CHEBI_35523) + +- [bronchodilator agent](http://purl.obolibrary.org/obo/CHEBI_35523) SubClassOf [drug](http://purl.obolibrary.org/obo/CHEBI_23888) + + + +### brush cell of bronchus `http://purl.obolibrary.org/obo/CL_0002208` +#### Removed +- [brush cell of bronchus](http://purl.obolibrary.org/obo/CL_0002208) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000389" + + + +### brush cell of epithelium proper of large intestine `http://purl.obolibrary.org/obo/CL_0002203` +#### Removed +- [brush cell of epithelium proper of large intestine](http://purl.obolibrary.org/obo/CL_0002203) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000387" + + + +### brush cell of lobular bronchiole `http://purl.obolibrary.org/obo/CL_0002205` +#### Removed +- [brush cell of lobular bronchiole](http://purl.obolibrary.org/obo/CL_0002205) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000386" + + + +### brush cell of terminal bronchiole `http://purl.obolibrary.org/obo/CL_0002206` +#### Removed +- [brush cell of terminal bronchiole](http://purl.obolibrary.org/obo/CL_0002206) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000390" + + + +### brush cell of trachea `http://purl.obolibrary.org/obo/CL_0002207` +#### Removed +- [brush cell of trachea](http://purl.obolibrary.org/obo/CL_0002207) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000388" + + + +### butyrate `http://purl.obolibrary.org/obo/CHEBI_17968` +#### Removed +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [label](http://www.w3.org/2000/01/rdf-schema#label) "butyrate" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butanoate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "butanate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22946" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "1-butyrate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13924" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:7496326" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00246" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "FERIUCNNQQJTOY-UHFFFAOYSA-M" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)/p-1" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:BUTYRIC_ACID" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "butanoate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C4H7O2" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CH3-[CH2]2-COO(-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group." + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "butanoic acid, ion(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [mass](http://purl.obolibrary.org/obo/chebi/mass) "87.09718" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "propanecarboxylate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "propylformate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:3601060" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "CCCC([O-])=O" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:3601060" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butyrate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "n-butyrate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "1-butanoate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "1-propanecarboxylate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UM-BBD_compID:c0035" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "UM-BBD" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:461-55-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "87.04515" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17190852" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "butanoate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:17968" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "n-butanoate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:324289" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- Class: [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [EC 3.5.1.98 (histone deacetylase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_61115) + +- [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) SubClassOf [fatty acid anion 4:0](http://purl.obolibrary.org/obo/CHEBI_78115) + + + +### butyrate biosynthetic process `http://purl.obolibrary.org/obo/GO_0046358` +#### Removed +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of butyrate, the anion of butyric acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0043439" + +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butyrate anabolism" + +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butanoic acid synthesis" + +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butanoic acid biosynthetic process" + +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butanoic acid formation" + +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butanoic acid anabolism" + +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butyrate biosynthesis" + +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) [label](http://www.w3.org/2000/01/rdf-schema#label) "butyrate biosynthetic process" + +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butyrate formation" + +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butanoic acid biosynthesis" + +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046358" + +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butyrate synthesis" + +- Class: [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) + +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968)) + +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) SubClassOf [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) + +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) + +- [butyrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0046358) SubClassOf [short-chain fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051790) + + + +### butyrate catabolic process `http://purl.obolibrary.org/obo/GO_0046359` +#### Removed +- [butyrate catabolic process](http://purl.obolibrary.org/obo/GO_0046359) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046359" + +- [butyrate catabolic process](http://purl.obolibrary.org/obo/GO_0046359) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butyrate breakdown" + +- [butyrate catabolic process](http://purl.obolibrary.org/obo/GO_0046359) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0043440" + +- [butyrate catabolic process](http://purl.obolibrary.org/obo/GO_0046359) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butanoic acid catabolic process" + +- [butyrate catabolic process](http://purl.obolibrary.org/obo/GO_0046359) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butyrate catabolism" + +- [butyrate catabolic process](http://purl.obolibrary.org/obo/GO_0046359) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butyrate degradation" + +- [butyrate catabolic process](http://purl.obolibrary.org/obo/GO_0046359) [label](http://www.w3.org/2000/01/rdf-schema#label) "butyrate catabolic process" + +- [butyrate catabolic process](http://purl.obolibrary.org/obo/GO_0046359) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butanoic acid degradation" + +- [butyrate catabolic process](http://purl.obolibrary.org/obo/GO_0046359) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butanoic acid catabolism" + +- [butyrate catabolic process](http://purl.obolibrary.org/obo/GO_0046359) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butanoic acid breakdown" + +- [butyrate catabolic process](http://purl.obolibrary.org/obo/GO_0046359) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [butyrate catabolic process](http://purl.obolibrary.org/obo/GO_0046359) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of butyrate, the anion of butyric acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- Class: [butyrate catabolic process](http://purl.obolibrary.org/obo/GO_0046359) + +- [butyrate catabolic process](http://purl.obolibrary.org/obo/GO_0046359) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968)) + +- [butyrate catabolic process](http://purl.obolibrary.org/obo/GO_0046359) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) + +- [butyrate catabolic process](http://purl.obolibrary.org/obo/GO_0046359) SubClassOf [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) + +- [butyrate catabolic process](http://purl.obolibrary.org/obo/GO_0046359) SubClassOf [short-chain fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0019626) + + + +### butyrate metabolic process `http://purl.obolibrary.org/obo/GO_0019605` +#### Removed +- [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butyrate metabolism" + +- [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butanoic acid metabolic process" + +- [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butyric acid metabolism" + +- [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving any butyrate, the anions of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0019605" + +- [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butanoic acid metabolism" + +- [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0043437" + +- [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) [label](http://www.w3.org/2000/01/rdf-schema#label) "butyrate metabolic process" + +- [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butyric acid metabolic process" + +- Class: [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) + +- [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968)) + +- [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) + +- [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) SubClassOf [short-chain fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0046459) + + + +### butyric acid `http://purl.obolibrary.org/obo/CHEBI_30772` +#### Removed +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15810631" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LIPID_MAPS_instance:LMFA01010004" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "LIPID MAPS" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:107-92-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10736622" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "C4:0" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Butanoate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:113450" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:13678314" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00246" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "1-butanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "butoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C4H8O2" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00001180" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4:0" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:BUTYRIC_ACID" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:26242" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group." + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "88.05243" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15809727" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CH3-[CH2]2-COOH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:906770" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11305323" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22038864" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19703412" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "CCCC(O)=O" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "1-butyric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [label](http://www.w3.org/2000/01/rdf-schema#label) "butyric acid" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:906770" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10956204" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChEMBL" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22466881" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22339023" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "n-butyric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Butyric_acid" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21699495" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11201044" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Butyric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19366864" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15938880" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "butanic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acide butyrique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "propylformic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "propanecarboxylic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22322557" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "FERIUCNNQQJTOY-UHFFFAOYSA-N" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22948" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22194341" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:14962641" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:3234" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12068484" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "1-propanecarboxylic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:107-92-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Buttersaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Butanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:BUA" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:107-92-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11208715" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "n-butanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acide butanoique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ethylacetic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19318247" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [mass](http://purl.obolibrary.org/obo/chebi/mass) "88.10510" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "BUTANOIC ACID" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB03568" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:1542095" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChEMBL" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000039" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11238216" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:41208" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:30772" + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butyric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- Class: [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human urinary metabolite](http://purl.obolibrary.org/obo/CHEBI_84087) + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) SubClassOf [straight-chain saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_39418) + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) SubClassOf [fatty acid 4:0](http://purl.obolibrary.org/obo/CHEBI_140601) + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) + +- [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Mycoplasma genitalium metabolite](http://purl.obolibrary.org/obo/CHEBI_131604) + + + +### calcitonin `http://purl.obolibrary.org/obo/CHEBI_3306` +#### Removed +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:8186880" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C06865" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "calcitonin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [label](http://www.w3.org/2000/01/rdf-schema#label) "calcitonin" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D00249" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Calcitonin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:47931-85-1" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Salmon calcitonin-(1-32)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "3429.71331" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A 32-membered heterodetic cyclic peptide comprising the sequence Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 cyclised by a disulfide bridge between the two Cys residues at positions 1 and 7." + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "N-{[(4R,7S,10S,13S,16S,19S,22R)-22-amino-16-(2-amino-2-oxoethyl)-7-[(1R)-1-hydroxyethyl]-10,19-bis(hydroxymethyl)-13-isobutyl-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosan-4-yl]carbonyl}-L-valyl-L-leucylglycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparaginyl-L-threonylglycyl-L-serylglycyl-L-threonyl-L-prolinamide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(N)=O" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:47931-85-1" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "BBBFJLBPOGFECG-VJVYQDLKSA-N" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Thyrocalcitonin (salmon)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Calcitonin, salmon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C145H240N44O48S2/c1-65(2)45-86(175-139(232)110(70(11)12)183-136(229)99-63-239-238-62-79(148)117(210)178-96(59-191)134(227)174-92(52-104(151)202)131(224)172-90(49-69(9)10)129(222)180-98(61-193)135(228)187-114(74(16)197)142(235)181-99)118(211)158-55-106(204)162-80(25-18-20-40-146)120(213)169-89(48-68(7)8)128(221)179-97(60-192)133(226)167-83(34-37-102(149)200)122(215)165-85(36-39-109(207)208)123(216)171-88(47-67(5)6)127(220)173-91(51-77-54-156-64-161-77)130(223)164-81(26-19-21-41-147)121(214)170-87(46-66(3)4)126(219)166-84(35-38-103(150)201)125(218)186-113(73(15)196)141(234)177-94(50-76-30-32-78(199)33-31-76)143(236)189-44-24-29-101(189)137(230)168-82(27-22-42-157-145(154)155)124(217)185-112(72(14)195)140(233)176-93(53-105(152)203)132(225)184-111(71(13)194)138(231)160-56-107(205)163-95(58-190)119(212)159-57-108(206)182-115(75(17)198)144(237)188-43-23-28-100(188)116(153)209/h30-33,54,64-75,79-101,110-115,190-199H,18-29,34-53,55-63,146-148H2,1-17H3,(H2,149,200)(H2,150,201)(H2,151,202)(H2,152,203)(H2,153,209)(H,156,161)(H,158,211)(H,159,212)(H,160,231)(H,162,204)(H,163,205)(H,164,223)(H,165,215)(H,166,219)(H,167,226)(H,168,230)(H,169,213)(H,170,214)(H,171,216)(H,172,224)(H,173,220)(H,174,227)(H,175,232)(H,176,233)(H,177,234)(H,178,210)(H,179,221)(H,180,222)(H,181,235)(H,182,206)(H,183,229)(H,184,225)(H,185,217)(H,186,218)(H,187,228)(H,207,208)(H4,154,155,157)/t71-,72-,73-,74-,75-,79+,80+,81+,82+,83+,84+,85+,86+,87+,88+,89+,90+,91+,92+,93+,94+,95+,96+,97+,98+,99+,100+,101+,110+,111+,112+,113+,114+,115+/m1/s1" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB00017" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [mass](http://purl.obolibrary.org/obo/chebi/mass) "3431.85300" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:9007-12-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:2989" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Cibacalcin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Salmotonin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C145H240N44O48S2" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:3306" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Calcitonin" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Salmon calcitonin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cyclo-[Cys-Ser-Asn-Leu-Ser-Thr-Cys]-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) SubClassOf [heterodetic cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_24533) + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [bone density conservation agent](http://purl.obolibrary.org/obo/CHEBI_50646) + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) SubClassOf [peptide hormone](http://purl.obolibrary.org/obo/CHEBI_25905) + +- [calcitonin](http://purl.obolibrary.org/obo/CHEBI_3306) SubClassOf [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) + + + +### calcitonin catabolic process `http://purl.obolibrary.org/obo/GO_0010816` +#### Removed +- [calcitonin catabolic process](http://purl.obolibrary.org/obo/GO_0010816) SubClassOf [peptide catabolic process](http://purl.obolibrary.org/obo/GO_0043171) + + + +### calcium activated cation channel activity `http://purl.obolibrary.org/obo/GO_0005227` + +#### Added +- [calcium activated cation channel activity](http://purl.obolibrary.org/obo/GO_0005227) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24605"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [calcium activated cation channel activity](http://purl.obolibrary.org/obo/GO_0005227) EquivalentTo [gated channel activity](http://purl.obolibrary.org/obo/GO_0022836) and ([positively regulated by](http://purl.obolibrary.org/obo/RO_0002336) some [calcium ion binding](http://purl.obolibrary.org/obo/GO_0005509)) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [monoatomic cation](http://purl.obolibrary.org/obo/CHEBI_23906)) + +- [calcium activated cation channel activity](http://purl.obolibrary.org/obo/GO_0005227) SubClassOf [monoatomic cation channel activity](http://purl.obolibrary.org/obo/GO_0005261) + +- [calcium activated cation channel activity](http://purl.obolibrary.org/obo/GO_0005227) SubClassOf [positively regulated by](http://purl.obolibrary.org/obo/RO_0002336) some [calcium ion binding](http://purl.obolibrary.org/obo/GO_0005509) + + +### calcium atom `http://purl.obolibrary.org/obo/CHEBI_22984` +#### Removed +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "20Ca" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [mass](http://purl.obolibrary.org/obo/chebi/mass) "40.07800" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [label](http://www.w3.org/2000/01/rdf-schema#label) "calcium atom" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[Ca]" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "OYPRJOBELJOOCE-UHFFFAOYSA-N" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ca" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "calcium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Calcium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "39.96259" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/Ca" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "calcio" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Kalzium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB01373" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7440-70-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:22984" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ca" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "calcium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [formula](http://purl.obolibrary.org/obo/chebi/formula) "Ca" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WebElements:Ca" + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00076" + +- Class: [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [macronutrient](http://purl.obolibrary.org/obo/CHEBI_33937) + +- [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) SubClassOf [alkaline earth metal atom](http://purl.obolibrary.org/obo/CHEBI_22313) + + + +### calcium cation `http://purl.obolibrary.org/obo/CHEBI_39123` +#### Removed +- [calcium cation](http://purl.obolibrary.org/obo/CHEBI_39123) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [calcium cation](http://purl.obolibrary.org/obo/CHEBI_39123) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "calcium cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [calcium cation](http://purl.obolibrary.org/obo/CHEBI_39123) [mass](http://purl.obolibrary.org/obo/chebi/mass) "40.078" + +- [calcium cation](http://purl.obolibrary.org/obo/CHEBI_39123) [label](http://www.w3.org/2000/01/rdf-schema#label) "calcium cation" + +- [calcium cation](http://purl.obolibrary.org/obo/CHEBI_39123) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:39123" + +- [calcium cation](http://purl.obolibrary.org/obo/CHEBI_39123) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "calcium cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [calcium cation](http://purl.obolibrary.org/obo/CHEBI_39123) [formula](http://purl.obolibrary.org/obo/chebi/formula) "Ca" + +- [calcium cation](http://purl.obolibrary.org/obo/CHEBI_39123) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [calcium cation](http://purl.obolibrary.org/obo/CHEBI_39123) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "39.96259" + +- Class: [calcium cation](http://purl.obolibrary.org/obo/CHEBI_39123) + +- [calcium cation](http://purl.obolibrary.org/obo/CHEBI_39123) SubClassOf [alkaline earth cation](http://purl.obolibrary.org/obo/CHEBI_33513) + +- [calcium cation](http://purl.obolibrary.org/obo/CHEBI_39123) SubClassOf [calcium ion](http://purl.obolibrary.org/obo/CHEBI_39124) + + + +### calcium channel activity `http://purl.obolibrary.org/obo/GO_0005262` +#### Removed +- [calcium channel activity](http://purl.obolibrary.org/obo/GO_0005262) SubClassOf [monoatomic cation channel activity](http://purl.obolibrary.org/obo/GO_0005261) + +#### Added +- [calcium channel activity](http://purl.obolibrary.org/obo/GO_0005262) SubClassOf [channel activity](http://purl.obolibrary.org/obo/GO_0015267) + + +### calcium channel inhibitor activity `http://purl.obolibrary.org/obo/GO_0019855` +#### Removed +- [calcium channel inhibitor activity](http://purl.obolibrary.org/obo/GO_0019855) SubClassOf [ion channel inhibitor activity](http://purl.obolibrary.org/obo/GO_0008200) + +#### Added +- [calcium channel inhibitor activity](http://purl.obolibrary.org/obo/GO_0019855) SubClassOf [channel inhibitor activity](http://purl.obolibrary.org/obo/GO_0016248) + + +### calcium channel regulator activity `http://purl.obolibrary.org/obo/GO_0005246` +#### Removed +- [calcium channel regulator activity](http://purl.obolibrary.org/obo/GO_0005246) SubClassOf [ion channel regulator activity](http://purl.obolibrary.org/obo/GO_0099106) + +#### Added +- [calcium channel regulator activity](http://purl.obolibrary.org/obo/GO_0005246) SubClassOf [channel regulator activity](http://purl.obolibrary.org/obo/GO_0016247) + + +### calcium ion `http://purl.obolibrary.org/obo/CHEBI_39124` +#### Removed +- [calcium ion](http://purl.obolibrary.org/obo/CHEBI_39124) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:39124" + +- [calcium ion](http://purl.obolibrary.org/obo/CHEBI_39124) [mass](http://purl.obolibrary.org/obo/chebi/mass) "40.078" + +- [calcium ion](http://purl.obolibrary.org/obo/CHEBI_39124) [label](http://www.w3.org/2000/01/rdf-schema#label) "calcium ion" + +- [calcium ion](http://purl.obolibrary.org/obo/CHEBI_39124) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [calcium ion](http://purl.obolibrary.org/obo/CHEBI_39124) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [calcium ion](http://purl.obolibrary.org/obo/CHEBI_39124) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "calcium ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [calcium ion](http://purl.obolibrary.org/obo/CHEBI_39124) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "calcium ions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [calcium ion](http://purl.obolibrary.org/obo/CHEBI_39124) [formula](http://purl.obolibrary.org/obo/chebi/formula) "Ca" + +- [calcium ion](http://purl.obolibrary.org/obo/CHEBI_39124) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "39.96259" + +- [calcium ion](http://purl.obolibrary.org/obo/CHEBI_39124) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- Class: [calcium ion](http://purl.obolibrary.org/obo/CHEBI_39124) + +- [calcium ion](http://purl.obolibrary.org/obo/CHEBI_39124) SubClassOf [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) + +- [calcium ion](http://purl.obolibrary.org/obo/CHEBI_39124) SubClassOf [elemental calcium](http://purl.obolibrary.org/obo/CHEBI_35155) + + + +### calcium ion binding `http://purl.obolibrary.org/obo/GO_0005509` +#### Removed +- [calcium ion binding](http://purl.obolibrary.org/obo/GO_0005509) SubClassOf [metal ion binding](http://purl.obolibrary.org/obo/GO_0046872) + +#### Added +- [calcium ion binding](http://purl.obolibrary.org/obo/GO_0005509) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### calcium ion homeostasis `http://purl.obolibrary.org/obo/GO_0055074` +#### Removed +- [calcium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055074) SubClassOf [inorganic ion homeostasis](http://purl.obolibrary.org/obo/GO_0098771) + +- [calcium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055074) SubClassOf [monoatomic cation homeostasis](http://purl.obolibrary.org/obo/GO_0055080) + +#### Added +- [calcium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055074) SubClassOf [chemical homeostasis](http://purl.obolibrary.org/obo/GO_0048878) + + +### calcium ion transmembrane transport `http://purl.obolibrary.org/obo/GO_0070588` +#### Removed +- [calcium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0070588) SubClassOf [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) + +- [calcium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0070588) SubClassOf [monoatomic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098655) + +#### Added +- [calcium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0070588) SubClassOf [transmembrane transport](http://purl.obolibrary.org/obo/GO_0055085) + + +### calcium ion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015085` +#### Removed +- [calcium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015085) SubClassOf [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) + +#### Added +- [calcium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015085) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + +### calcium ion transport `http://purl.obolibrary.org/obo/GO_0006816` +#### Removed +- [calcium ion transport](http://purl.obolibrary.org/obo/GO_0006816) SubClassOf [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) + +#### Added +- [calcium ion transport](http://purl.obolibrary.org/obo/GO_0006816) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### calcium molecular entity `http://purl.obolibrary.org/obo/CHEBI_22985` +#### Removed +- [calcium molecular entity](http://purl.obolibrary.org/obo/CHEBI_22985) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "calcium molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [calcium molecular entity](http://purl.obolibrary.org/obo/CHEBI_22985) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "calcium molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [calcium molecular entity](http://purl.obolibrary.org/obo/CHEBI_22985) [label](http://www.w3.org/2000/01/rdf-schema#label) "calcium molecular entity" + +- [calcium molecular entity](http://purl.obolibrary.org/obo/CHEBI_22985) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "calcium compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [calcium molecular entity](http://purl.obolibrary.org/obo/CHEBI_22985) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [calcium molecular entity](http://purl.obolibrary.org/obo/CHEBI_22985) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:22985" + +- [calcium molecular entity](http://purl.obolibrary.org/obo/CHEBI_22985) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [calcium molecular entity](http://purl.obolibrary.org/obo/CHEBI_22985) + +- [calcium molecular entity](http://purl.obolibrary.org/obo/CHEBI_22985) SubClassOf [alkaline earth molecular entity](http://purl.obolibrary.org/obo/CHEBI_33299) + +- [calcium molecular entity](http://purl.obolibrary.org/obo/CHEBI_22985) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [calcium atom](http://purl.obolibrary.org/obo/CHEBI_22984) + + + +### calcium(2+) `http://purl.obolibrary.org/obo/CHEBI_29108` +#### Removed +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "BHPQYMZQTOCNFJ-UHFFFAOYSA-N" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:3308" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [label](http://www.w3.org/2000/01/rdf-schema#label) "calcium(2+)" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:29108" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [mass](http://purl.obolibrary.org/obo/chebi/mass) "40.07800" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:14127-61-8" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "calcium(II) cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/Ca/q+2" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "calcium(2+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+2" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00076" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[Ca++]" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22988" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "39.96149" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:6850" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:48760" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ca2+" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ca(2+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [formula](http://purl.obolibrary.org/obo/chebi/formula) "Ca" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "calcium, doubly charged positive ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CALCIUM ION" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "calcium(2+) ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ca(2+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:14127-61-8" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:CA" + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) SubClassOf [divalent metal cation](http://purl.obolibrary.org/obo/CHEBI_60240) + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [cofactor](http://purl.obolibrary.org/obo/CHEBI_23357) + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) SubClassOf [monoatomic dication](http://purl.obolibrary.org/obo/CHEBI_30412) + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) SubClassOf [calcium cation](http://purl.obolibrary.org/obo/CHEBI_39123) + + + +### canonical deoxyribonucleoside residue `http://purl.obolibrary.org/obo/CHEBI_33793` +#### Removed +- [canonical deoxyribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33793) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "common 2'-deoxyribonucleoside residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CBN" + +- [canonical deoxyribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33793) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33793" + +- [canonical deoxyribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33793) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dNuc" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CBN" + +- [canonical deoxyribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33793) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [canonical deoxyribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33793) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "common 2'-deoxyribonucleoside residue" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CBN" + +- [canonical deoxyribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33793) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dN" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CBN" + +- [canonical deoxyribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33793) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "standard deoxyribonucleoside residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [canonical deoxyribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33793) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canonical deoxyribonucleoside residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [canonical deoxyribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33793) [label](http://www.w3.org/2000/01/rdf-schema#label) "canonical deoxyribonucleoside residue" + +- [canonical deoxyribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33793) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [canonical deoxyribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33793) + +- [canonical deoxyribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33793) SubClassOf [canonical nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33791) + + + +### canonical deoxyribonucleotide residue `http://purl.obolibrary.org/obo/CHEBI_50298` +#### Removed +- [canonical deoxyribonucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50298) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canonical deoxyribonucleotide residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [canonical deoxyribonucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50298) [label](http://www.w3.org/2000/01/rdf-schema#label) "canonical deoxyribonucleotide residue" + +- [canonical deoxyribonucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50298) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [canonical deoxyribonucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50298) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [canonical deoxyribonucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50298) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50298" + +- Class: [canonical deoxyribonucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50298) + +- [canonical deoxyribonucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50298) SubClassOf [canonical nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50297) + + + +### canonical nucleoside residue `http://purl.obolibrary.org/obo/CHEBI_33791` +#### Removed +- [canonical nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33791) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [canonical nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33791) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "common nucleoside residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CBN" + +- [canonical nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33791) [label](http://www.w3.org/2000/01/rdf-schema#label) "canonical nucleoside residue" + +- [canonical nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33791) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleoside residue" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CBN" + +- [canonical nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33791) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [canonical nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33791) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canonical nucleoside residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [canonical nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33791) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "standard nucleoside residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [canonical nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33791) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33791" + +- Class: [canonical nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33791) + +- [canonical nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33791) SubClassOf [nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_50320) + + + +### canonical nucleotide residue `http://purl.obolibrary.org/obo/CHEBI_50297` +#### Removed +- [canonical nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50297) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [canonical nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50297) [label](http://www.w3.org/2000/01/rdf-schema#label) "canonical nucleotide residue" + +- [canonical nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50297) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50297" + +- [canonical nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50297) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [canonical nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50297) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canonical nucleotide residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [canonical nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50297) + +- [canonical nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50297) SubClassOf [nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50319) + + + +### canonical ribonucleoside residue `http://purl.obolibrary.org/obo/CHEBI_33792` +#### Removed +- [canonical ribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33792) [label](http://www.w3.org/2000/01/rdf-schema#label) "canonical ribonucleoside residue" + +- [canonical ribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33792) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canonical ribonucleoside residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [canonical ribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33792) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Nuc" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CBN" + +- [canonical ribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33792) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "standard ribonucleoside residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [canonical ribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33792) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33792" + +- [canonical ribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33792) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [canonical ribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33792) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "common ribonucleoside residue" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CBN" + +- [canonical ribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33792) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "common ribonucleoside residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CBN" + +- [canonical ribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33792) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "N" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CBN" + +- [canonical ribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33792) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [canonical ribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33792) + +- [canonical ribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33792) SubClassOf [canonical nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33791) + + + +### canonical ribonucleotide residue `http://purl.obolibrary.org/obo/CHEBI_50299` +#### Removed +- [canonical ribonucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50299) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canonical ribonucleotide residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [canonical ribonucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50299) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [canonical ribonucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50299) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50299" + +- [canonical ribonucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50299) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [canonical ribonucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50299) [label](http://www.w3.org/2000/01/rdf-schema#label) "canonical ribonucleotide residue" + +- Class: [canonical ribonucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50299) + +- [canonical ribonucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50299) SubClassOf [canonical nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50297) + + + +### capable of `http://purl.obolibrary.org/obo/RO_0002215` +#### Removed +- [capable of](http://purl.obolibrary.org/obo/RO_0002215) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [capable of](http://purl.obolibrary.org/obo/RO_0002215) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### capable of part of `http://purl.obolibrary.org/obo/RO_0002216` +#### Removed +- [capable of part of](http://purl.obolibrary.org/obo/RO_0002216) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [capable of part of](http://purl.obolibrary.org/obo/RO_0002216) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### capillary of brain `http://purl.obolibrary.org/obo/UBERON_8480001` +#### Removed +- [capillary of brain](http://purl.obolibrary.org/obo/UBERON_8480001) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](http://orcid.org/0000-0002-0819-0473) + +#### Added +- [capillary of brain](http://purl.obolibrary.org/obo/UBERON_8480001) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](https://orcid.org/0000-0002-0819-0473) + + +### carbamate `http://purl.obolibrary.org/obo/CHEBI_13941` +#### Removed +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:13941" + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:302-11-4" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "KXDHJXZQYSOELW-UHFFFAOYSA-M" + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)/p-1" + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CH2NO2" + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:239604" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:3903503" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "60.00910" + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbamate ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [mass](http://purl.obolibrary.org/obo/chebi/mass) "60.03212" + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbamate" + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Karbamat" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "NC([O-])=O" + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Carbamat" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbamic acid, ion(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- Class: [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) + +- [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) SubClassOf [amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_37022) + + + +### carbamic acid `http://purl.obolibrary.org/obo/CHEBI_28616` +#### Removed +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:OUT" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Aminoformic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01563" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [mass](http://purl.obolibrary.org/obo/chebi/mass) "61.04006" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:463-77-4" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "KXDHJXZQYSOELW-UHFFFAOYSA-N" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbamic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:3386" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB04261" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Aminoameisensaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised." + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:463-77-4" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbamic acid" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23002" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Carbamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:28616" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Carbamic_acid" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:44573" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22504" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "CARBAMIC ACID" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "61.01638" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Carbamic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:130345" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Carbamidsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CH3NO2" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "NC(O)=O" + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:1734754" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- Class: [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) SubClassOf [organonitrogen compound](http://purl.obolibrary.org/obo/CHEBI_35352) + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) SubClassOf [one-carbon compound](http://purl.obolibrary.org/obo/CHEBI_64708) + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) + +- [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) SubClassOf [carbon oxoacid](http://purl.obolibrary.org/obo/CHEBI_35605) + + + +### carbamoyl group `http://purl.obolibrary.org/obo/CHEBI_23004` +#### Removed +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aminocarbonyl" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "44.01364" + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CH2NO" + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carboxamide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbamyl group" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbamyl" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "*C(N)=O" + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24168430" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:23004" + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbamoyl group" + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbamoyl" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "-CONH2" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [mass](http://purl.obolibrary.org/obo/chebi/mass) "44.03272" + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "-C(O)NH2" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid." + +- Class: [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) SubClassOf [is_substituent_group_from](http://purl.obolibrary.org/obo/chebi#is_substituent_group_from) some [carbamic acid](http://purl.obolibrary.org/obo/CHEBI_28616) + +- [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) SubClassOf [univalent carboacyl group](http://purl.obolibrary.org/obo/CHEBI_27207) + + + +### carboacyl group `http://purl.obolibrary.org/obo/CHEBI_37838` +#### Removed +- [carboacyl group](http://purl.obolibrary.org/obo/CHEBI_37838) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carboacyl group](http://purl.obolibrary.org/obo/CHEBI_37838) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carboacyl groups" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carboacyl group](http://purl.obolibrary.org/obo/CHEBI_37838) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carboxylic acyl group" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carboacyl group](http://purl.obolibrary.org/obo/CHEBI_37838) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carboacyl group](http://purl.obolibrary.org/obo/CHEBI_37838) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid." + +- [carboacyl group](http://purl.obolibrary.org/obo/CHEBI_37838) [label](http://www.w3.org/2000/01/rdf-schema#label) "carboacyl group" + +- [carboacyl group](http://purl.obolibrary.org/obo/CHEBI_37838) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:37838" + +- [carboacyl group](http://purl.obolibrary.org/obo/CHEBI_37838) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carboxylic acyl groups" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- Class: [carboacyl group](http://purl.obolibrary.org/obo/CHEBI_37838) + +- [carboacyl group](http://purl.obolibrary.org/obo/CHEBI_37838) SubClassOf [is_substituent_group_from](http://purl.obolibrary.org/obo/chebi#is_substituent_group_from) some [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) + +- [carboacyl group](http://purl.obolibrary.org/obo/CHEBI_37838) SubClassOf [acyl group](http://purl.obolibrary.org/obo/CHEBI_22221) + + + +### carbohydrate `http://purl.obolibrary.org/obo/CHEBI_16646` +#### Removed +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glucido" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Carbohydrate" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glucide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "saccharidum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbohidratos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbohidrato" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbohydrates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:16646" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Kohlenhydrate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "saccharide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glucides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:15131" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Kohlenhydrat" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "saccharides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23008" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:9318" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates." + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glucidos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrates de carbone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbohydrate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a carbohydrate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbohydrate" + +- [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) SubClassOf [carbohydrates and carbohydrate derivatives](http://purl.obolibrary.org/obo/CHEBI_78616) + + + +### carbohydrate acid `http://purl.obolibrary.org/obo/CHEBI_33720` +#### Removed +- [carbohydrate acid](http://purl.obolibrary.org/obo/CHEBI_33720) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33720" + +- [carbohydrate acid](http://purl.obolibrary.org/obo/CHEBI_33720) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbohydrate acid" + +- [carbohydrate acid](http://purl.obolibrary.org/obo/CHEBI_33720) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carbohydrate acid](http://purl.obolibrary.org/obo/CHEBI_33720) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbohydrate acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate acid](http://purl.obolibrary.org/obo/CHEBI_33720) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbohydrate acid](http://purl.obolibrary.org/obo/CHEBI_33720) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbohydrate acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [carbohydrate acid](http://purl.obolibrary.org/obo/CHEBI_33720) + +- [carbohydrate acid](http://purl.obolibrary.org/obo/CHEBI_33720) SubClassOf [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) + +- [carbohydrate acid](http://purl.obolibrary.org/obo/CHEBI_33720) SubClassOf [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) + +- [carbohydrate acid](http://purl.obolibrary.org/obo/CHEBI_33720) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [carbohydrate acid anion](http://purl.obolibrary.org/obo/CHEBI_33721) + + + +### carbohydrate acid anion `http://purl.obolibrary.org/obo/CHEBI_33721` +#### Removed +- [carbohydrate acid anion](http://purl.obolibrary.org/obo/CHEBI_33721) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carbohydrate acid anion](http://purl.obolibrary.org/obo/CHEBI_33721) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33721" + +- [carbohydrate acid anion](http://purl.obolibrary.org/obo/CHEBI_33721) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbohydrate acid anion](http://purl.obolibrary.org/obo/CHEBI_33721) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbohydrate acid anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate acid anion](http://purl.obolibrary.org/obo/CHEBI_33721) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbohydrate acid anion" + +- [carbohydrate acid anion](http://purl.obolibrary.org/obo/CHEBI_33721) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbohydrate acid anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [carbohydrate acid anion](http://purl.obolibrary.org/obo/CHEBI_33721) + +- [carbohydrate acid anion](http://purl.obolibrary.org/obo/CHEBI_33721) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [carbohydrate acid](http://purl.obolibrary.org/obo/CHEBI_33720) + +- [carbohydrate acid anion](http://purl.obolibrary.org/obo/CHEBI_33721) SubClassOf [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) + + + +### carbohydrate acid derivative `http://purl.obolibrary.org/obo/CHEBI_63436` +#### Removed +- [carbohydrate acid derivative](http://purl.obolibrary.org/obo/CHEBI_63436) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbohydrate acid derivatives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate acid derivative](http://purl.obolibrary.org/obo/CHEBI_63436) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:63436" + +- [carbohydrate acid derivative](http://purl.obolibrary.org/obo/CHEBI_63436) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbohydrate acid derivative" + +- [carbohydrate acid derivative](http://purl.obolibrary.org/obo/CHEBI_63436) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbohydrate acid derivative](http://purl.obolibrary.org/obo/CHEBI_63436) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A carbohydrate derivative that is formally obtained from a carbohydrate acid." + +- [carbohydrate acid derivative](http://purl.obolibrary.org/obo/CHEBI_63436) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [carbohydrate acid derivative](http://purl.obolibrary.org/obo/CHEBI_63436) + +- [carbohydrate acid derivative](http://purl.obolibrary.org/obo/CHEBI_63436) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [carbohydrate acid derivative anion](http://purl.obolibrary.org/obo/CHEBI_63551) + +- [carbohydrate acid derivative](http://purl.obolibrary.org/obo/CHEBI_63436) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [carbohydrate acid](http://purl.obolibrary.org/obo/CHEBI_33720) + +- [carbohydrate acid derivative](http://purl.obolibrary.org/obo/CHEBI_63436) SubClassOf [carbohydrate derivative](http://purl.obolibrary.org/obo/CHEBI_63299) + + + +### carbohydrate acid derivative anion `http://purl.obolibrary.org/obo/CHEBI_63551` +#### Removed +- [carbohydrate acid derivative anion](http://purl.obolibrary.org/obo/CHEBI_63551) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carbohydrate acid derivative anion](http://purl.obolibrary.org/obo/CHEBI_63551) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbohydrate acid anion derivative" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate acid derivative anion](http://purl.obolibrary.org/obo/CHEBI_63551) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbohydrate acid derivative anion](http://purl.obolibrary.org/obo/CHEBI_63551) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative." + +- [carbohydrate acid derivative anion](http://purl.obolibrary.org/obo/CHEBI_63551) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbohydrate acid derivative anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate acid derivative anion](http://purl.obolibrary.org/obo/CHEBI_63551) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbohydrate acid derivative anion" + +- [carbohydrate acid derivative anion](http://purl.obolibrary.org/obo/CHEBI_63551) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbohydrate acid anion derivatives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate acid derivative anion](http://purl.obolibrary.org/obo/CHEBI_63551) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:63551" + +- Class: [carbohydrate acid derivative anion](http://purl.obolibrary.org/obo/CHEBI_63551) + +- [carbohydrate acid derivative anion](http://purl.obolibrary.org/obo/CHEBI_63551) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [carbohydrate acid anion](http://purl.obolibrary.org/obo/CHEBI_33721) + +- [carbohydrate acid derivative anion](http://purl.obolibrary.org/obo/CHEBI_63551) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [carbohydrate acid derivative](http://purl.obolibrary.org/obo/CHEBI_63436) + +- [carbohydrate acid derivative anion](http://purl.obolibrary.org/obo/CHEBI_63551) SubClassOf [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) + + + +### carbohydrate biosynthetic process `http://purl.obolibrary.org/obo/GO_0016051` +#### Removed +- [carbohydrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0016051) SubClassOf [organic substance biosynthetic process](http://purl.obolibrary.org/obo/GO_1901576) + +#### Added +- [carbohydrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0016051) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### carbohydrate catabolic process `http://purl.obolibrary.org/obo/GO_0016052` +#### Removed +- [carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0016052) SubClassOf [organic substance catabolic process](http://purl.obolibrary.org/obo/GO_1901575) + +#### Added +- [carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0016052) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### carbohydrate derivative `http://purl.obolibrary.org/obo/CHEBI_63299` +#### Removed +- [carbohydrate derivative](http://purl.obolibrary.org/obo/CHEBI_63299) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "derivatized carbohydrates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate derivative](http://purl.obolibrary.org/obo/CHEBI_63299) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "derivatised carbohydrate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate derivative](http://purl.obolibrary.org/obo/CHEBI_63299) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbohydrate derivative" + +- [carbohydrate derivative](http://purl.obolibrary.org/obo/CHEBI_63299) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "derivatised carbohydrates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate derivative](http://purl.obolibrary.org/obo/CHEBI_63299) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbohydrate derivatives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate derivative](http://purl.obolibrary.org/obo/CHEBI_63299) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds." + +- [carbohydrate derivative](http://purl.obolibrary.org/obo/CHEBI_63299) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:63299" + +- [carbohydrate derivative](http://purl.obolibrary.org/obo/CHEBI_63299) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "derivatized carbohydrate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate derivative](http://purl.obolibrary.org/obo/CHEBI_63299) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carbohydrate derivative](http://purl.obolibrary.org/obo/CHEBI_63299) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbohydrate derivative](http://purl.obolibrary.org/obo/CHEBI_63299) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) + +- [carbohydrate derivative](http://purl.obolibrary.org/obo/CHEBI_63299) SubClassOf [carbohydrates and carbohydrate derivatives](http://purl.obolibrary.org/obo/CHEBI_78616) + + + +### carbohydrate derivative biosynthetic process `http://purl.obolibrary.org/obo/GO_1901137` +#### Removed +- [carbohydrate derivative biosynthetic process](http://purl.obolibrary.org/obo/GO_1901137) SubClassOf [organic substance biosynthetic process](http://purl.obolibrary.org/obo/GO_1901576) + +#### Added +- [carbohydrate derivative biosynthetic process](http://purl.obolibrary.org/obo/GO_1901137) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### carbohydrate derivative catabolic process `http://purl.obolibrary.org/obo/GO_1901136` +#### Removed +- [carbohydrate derivative catabolic process](http://purl.obolibrary.org/obo/GO_1901136) SubClassOf [organic substance catabolic process](http://purl.obolibrary.org/obo/GO_1901575) + +#### Added +- [carbohydrate derivative catabolic process](http://purl.obolibrary.org/obo/GO_1901136) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### carbohydrate derivative metabolic process `http://purl.obolibrary.org/obo/GO_1901135` +#### Removed +- [carbohydrate derivative metabolic process](http://purl.obolibrary.org/obo/GO_1901135) SubClassOf [organic substance metabolic process](http://purl.obolibrary.org/obo/GO_0071704) + +#### Added +- [carbohydrate derivative metabolic process](http://purl.obolibrary.org/obo/GO_1901135) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### carbohydrate derivative transport `http://purl.obolibrary.org/obo/GO_1901264` +#### Removed +- [carbohydrate derivative transport](http://purl.obolibrary.org/obo/GO_1901264) SubClassOf [organic substance transport](http://purl.obolibrary.org/obo/GO_0071702) + +#### Added +- [carbohydrate derivative transport](http://purl.obolibrary.org/obo/GO_1901264) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### carbohydrate metabolic process `http://purl.obolibrary.org/obo/GO_0005975` +#### Removed +- [carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0005975) SubClassOf [organic substance metabolic process](http://purl.obolibrary.org/obo/GO_0071704) + + + +### carbohydrate sulfate `http://purl.obolibrary.org/obo/CHEBI_35724` +#### Removed +- [carbohydrate sulfate](http://purl.obolibrary.org/obo/CHEBI_35724) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35724" + +- [carbohydrate sulfate](http://purl.obolibrary.org/obo/CHEBI_35724) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbohydrate sulfate" + +- [carbohydrate sulfate](http://purl.obolibrary.org/obo/CHEBI_35724) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbohydrate sulfates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate sulfate](http://purl.obolibrary.org/obo/CHEBI_35724) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbohydrate sulfate](http://purl.obolibrary.org/obo/CHEBI_35724) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbohydrate sulphates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrate sulfate](http://purl.obolibrary.org/obo/CHEBI_35724) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [carbohydrate sulfate](http://purl.obolibrary.org/obo/CHEBI_35724) + +- [carbohydrate sulfate](http://purl.obolibrary.org/obo/CHEBI_35724) SubClassOf [carbohydrate derivative](http://purl.obolibrary.org/obo/CHEBI_63299) + +- [carbohydrate sulfate](http://purl.obolibrary.org/obo/CHEBI_35724) SubClassOf [sulfuric ester](http://purl.obolibrary.org/obo/CHEBI_26819) + +- [carbohydrate sulfate](http://purl.obolibrary.org/obo/CHEBI_35724) SubClassOf [organic sulfate](http://purl.obolibrary.org/obo/CHEBI_25704) + + + +### carbohydrate transport `http://purl.obolibrary.org/obo/GO_0008643` +#### Removed +- [carbohydrate transport](http://purl.obolibrary.org/obo/GO_0008643) SubClassOf [organic substance transport](http://purl.obolibrary.org/obo/GO_0071702) + +#### Added +- [carbohydrate transport](http://purl.obolibrary.org/obo/GO_0008643) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### carbohydrates and carbohydrate derivatives `http://purl.obolibrary.org/obo/CHEBI_78616` +#### Removed +- [carbohydrates and carbohydrate derivatives](http://purl.obolibrary.org/obo/CHEBI_78616) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbohydrates and carbohydrate derivatives" + +- [carbohydrates and carbohydrate derivatives](http://purl.obolibrary.org/obo/CHEBI_78616) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carbohydrates and carbohydrate derivatives](http://purl.obolibrary.org/obo/CHEBI_78616) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbohydrates and their derivatives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrates and carbohydrate derivatives](http://purl.obolibrary.org/obo/CHEBI_78616) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:78616" + +- [carbohydrates and carbohydrate derivatives](http://purl.obolibrary.org/obo/CHEBI_78616) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbohydrates and derivatives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbohydrates and carbohydrate derivatives](http://purl.obolibrary.org/obo/CHEBI_78616) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation." + +- [carbohydrates and carbohydrate derivatives](http://purl.obolibrary.org/obo/CHEBI_78616) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [carbohydrates and carbohydrate derivatives](http://purl.obolibrary.org/obo/CHEBI_78616) + +- [carbohydrates and carbohydrate derivatives](http://purl.obolibrary.org/obo/CHEBI_78616) SubClassOf [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) + + + +### carbon atom `http://purl.obolibrary.org/obo/CHEBI_27594` +#### Removed +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7440-44-0" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbonium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "C" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7440-44-0" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Carbon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "12.00000" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "C" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Kohlenstoff" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[C]" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C06265" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbon atom" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:3399" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:27594" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "6C" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbono" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [mass](http://purl.obolibrary.org/obo/chebi/mass) "12.01070" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WebElements:C" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "OKTJSMMVPCPJKN-UHFFFAOYSA-N" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C" + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23009" + +- Class: [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [macronutrient](http://purl.obolibrary.org/obo/CHEBI_33937) + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) SubClassOf [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) + +- [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) SubClassOf [carbon group element atom](http://purl.obolibrary.org/obo/CHEBI_33306) + + + +### carbon group element atom `http://purl.obolibrary.org/obo/CHEBI_33306` +#### Removed +- [carbon group element atom](http://purl.obolibrary.org/obo/CHEBI_33306) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbonoides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbon group element atom](http://purl.obolibrary.org/obo/CHEBI_33306) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "group IV elements" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbon group element atom](http://purl.obolibrary.org/obo/CHEBI_33306) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carbon group element atom](http://purl.obolibrary.org/obo/CHEBI_33306) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbon group elements" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbon group element atom](http://purl.obolibrary.org/obo/CHEBI_33306) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbon group element atom" + +- [carbon group element atom](http://purl.obolibrary.org/obo/CHEBI_33306) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33306" + +- [carbon group element atom](http://purl.obolibrary.org/obo/CHEBI_33306) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "group 14 elements" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carbon group element atom](http://purl.obolibrary.org/obo/CHEBI_33306) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cristallogenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbon group element atom](http://purl.obolibrary.org/obo/CHEBI_33306) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbon group element atom](http://purl.obolibrary.org/obo/CHEBI_33306) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cristallogene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbon group element atom](http://purl.obolibrary.org/obo/CHEBI_33306) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbon group element" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [carbon group element atom](http://purl.obolibrary.org/obo/CHEBI_33306) + +- [carbon group element atom](http://purl.obolibrary.org/obo/CHEBI_33306) SubClassOf [p-block element atom](http://purl.obolibrary.org/obo/CHEBI_33560) + + + +### carbon group molecular entity `http://purl.obolibrary.org/obo/CHEBI_33582` +#### Removed +- [carbon group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33582) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33582" + +- [carbon group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33582) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbon group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33582) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbon group molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbon group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33582) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbon group molecular entity" + +- [carbon group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33582) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbon group molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [carbon group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33582) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbon group molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbon group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33582) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbon group molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [carbon group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33582) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [carbon group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33582) + +- [carbon group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33582) SubClassOf [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) + +- [carbon group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33582) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [carbon group element atom](http://purl.obolibrary.org/obo/CHEBI_33306) + + + +### carbon oxoacid `http://purl.obolibrary.org/obo/CHEBI_35605` +#### Removed +- [carbon oxoacid](http://purl.obolibrary.org/obo/CHEBI_35605) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxoacids of carbon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbon oxoacid](http://purl.obolibrary.org/obo/CHEBI_35605) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbon oxoacid" + +- [carbon oxoacid](http://purl.obolibrary.org/obo/CHEBI_35605) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35605" + +- [carbon oxoacid](http://purl.obolibrary.org/obo/CHEBI_35605) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carbon oxoacid](http://purl.obolibrary.org/obo/CHEBI_35605) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbon oxoacids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbon oxoacid](http://purl.obolibrary.org/obo/CHEBI_35605) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [carbon oxoacid](http://purl.obolibrary.org/obo/CHEBI_35605) + +- [carbon oxoacid](http://purl.obolibrary.org/obo/CHEBI_35605) SubClassOf [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) + +- [carbon oxoacid](http://purl.obolibrary.org/obo/CHEBI_35605) SubClassOf [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) + + + +### carbon oxoanion `http://purl.obolibrary.org/obo/CHEBI_35604` +#### Removed +- [carbon oxoanion](http://purl.obolibrary.org/obo/CHEBI_35604) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbon oxoanions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbon oxoanion](http://purl.obolibrary.org/obo/CHEBI_35604) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxocarbon anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbon oxoanion](http://purl.obolibrary.org/obo/CHEBI_35604) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbon oxoanion](http://purl.obolibrary.org/obo/CHEBI_35604) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carbon oxoanion](http://purl.obolibrary.org/obo/CHEBI_35604) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35604" + +- [carbon oxoanion](http://purl.obolibrary.org/obo/CHEBI_35604) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbon oxoanion" + +- [carbon oxoanion](http://purl.obolibrary.org/obo/CHEBI_35604) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxocarbon anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbon oxoanion](http://purl.obolibrary.org/obo/CHEBI_35604) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n." + +- [carbon oxoanion](http://purl.obolibrary.org/obo/CHEBI_35604) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbon oxoanion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [carbon oxoanion](http://purl.obolibrary.org/obo/CHEBI_35604) + +- [carbon oxoanion](http://purl.obolibrary.org/obo/CHEBI_35604) SubClassOf [organic anion](http://purl.obolibrary.org/obo/CHEBI_25696) + +- [carbon oxoanion](http://purl.obolibrary.org/obo/CHEBI_35604) SubClassOf [oxoanion](http://purl.obolibrary.org/obo/CHEBI_35406) + +- [carbon oxoanion](http://purl.obolibrary.org/obo/CHEBI_35604) SubClassOf [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) + + + +### carbonate `http://purl.obolibrary.org/obo/CHEBI_41609` +#### Removed +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CO3(2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbonate" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[O-]C([O-])=O" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:CO3" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:3600898" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:41605" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Karbonat" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "trioxidocarbonate(2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "59.98584" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CO3" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:29201" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbonate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CARBONATE ION" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [mass](http://purl.obolibrary.org/obo/chebi/mass) "60.00890" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:1559" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:3812-32-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[CO3](2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:41609" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-2" + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "BVKZGUZCCUSVTD-UHFFFAOYSA-L" + +- Class: [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) + +- [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) SubClassOf [carbon oxoanion](http://purl.obolibrary.org/obo/CHEBI_35604) + + + +### carbonic acid `http://purl.obolibrary.org/obo/CHEBI_28976` +#### Removed +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "BVKZGUZCCUSVTD-UHFFFAOYSA-N" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "H2CO3" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbonic acid" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:463-79-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:3401" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CH2O3" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "OC(O)=O" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Koehlensaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [mass](http://purl.obolibrary.org/obo/chebi/mass) "62.02478" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "H2CO3" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dihydroxidooxidocarbon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23017" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbonic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "62.00039" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:463-79-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:CO3" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[CO(OH)2]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13351" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01353" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Carbonic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:25554" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:28976" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23744" + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Dihydrogen carbonate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- Class: [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) SubClassOf [chalcocarbonic acid](http://purl.obolibrary.org/obo/CHEBI_36961) + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) SubClassOf [carbon oxoacid](http://purl.obolibrary.org/obo/CHEBI_35605) + + + +### carbonyl compound `http://purl.obolibrary.org/obo/CHEBI_36586` +#### Removed +- [carbonyl compound](http://purl.obolibrary.org/obo/CHEBI_36586) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbonyl compound" + +- [carbonyl compound](http://purl.obolibrary.org/obo/CHEBI_36586) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbonyl compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [carbonyl compound](http://purl.obolibrary.org/obo/CHEBI_36586) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbonyl compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carbonyl compound](http://purl.obolibrary.org/obo/CHEBI_36586) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbonyl compound](http://purl.obolibrary.org/obo/CHEBI_36586) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [carbonyl compound](http://purl.obolibrary.org/obo/CHEBI_36586) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carbonyl compound](http://purl.obolibrary.org/obo/CHEBI_36586) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36586" + +- Class: [carbonyl compound](http://purl.obolibrary.org/obo/CHEBI_36586) + +- [carbonyl compound](http://purl.obolibrary.org/obo/CHEBI_36586) SubClassOf [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) + +- [carbonyl compound](http://purl.obolibrary.org/obo/CHEBI_36586) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [carbonyl group](http://purl.obolibrary.org/obo/CHEBI_23019) + +- [carbonyl compound](http://purl.obolibrary.org/obo/CHEBI_36586) SubClassOf [organic oxo compound](http://purl.obolibrary.org/obo/CHEBI_36587) + + + +### carbonyl group `http://purl.obolibrary.org/obo/CHEBI_23019` +#### Removed +- [carbonyl group](http://purl.obolibrary.org/obo/CHEBI_23019) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) ">C=O" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carbonyl group](http://purl.obolibrary.org/obo/CHEBI_23019) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbonyl group" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carbonyl group](http://purl.obolibrary.org/obo/CHEBI_23019) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CO" + +- [carbonyl group](http://purl.obolibrary.org/obo/CHEBI_23019) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:23019" + +- [carbonyl group](http://purl.obolibrary.org/obo/CHEBI_23019) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "O=C(*)*" + +- [carbonyl group](http://purl.obolibrary.org/obo/CHEBI_23019) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carbonyl group](http://purl.obolibrary.org/obo/CHEBI_23019) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbonyl" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carbonyl group](http://purl.obolibrary.org/obo/CHEBI_23019) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "27.99491" + +- [carbonyl group](http://purl.obolibrary.org/obo/CHEBI_23019) [label](http://www.w3.org/2000/01/rdf-schema#label) "carbonyl group" + +- [carbonyl group](http://purl.obolibrary.org/obo/CHEBI_23019) [mass](http://purl.obolibrary.org/obo/chebi/mass) "28.01010" + +- [carbonyl group](http://purl.obolibrary.org/obo/CHEBI_23019) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [carbonyl group](http://purl.obolibrary.org/obo/CHEBI_23019) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbonyl group" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [carbonyl group](http://purl.obolibrary.org/obo/CHEBI_23019) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [carbonyl group](http://purl.obolibrary.org/obo/CHEBI_23019) + +- [carbonyl group](http://purl.obolibrary.org/obo/CHEBI_23019) SubClassOf [organodiyl group](http://purl.obolibrary.org/obo/CHEBI_51422) + + + +### carboxamide `http://purl.obolibrary.org/obo/CHEBI_37622` +#### Removed +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "primary carboxamide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:35354" + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carboxamides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [mass](http://purl.obolibrary.org/obo/chebi/mass) "42.01680" + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[*]C(=O)N([*])[*]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [SMILES](http://purl.obolibrary.org/obo/fbbt#SMILES) + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CNOR3" + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[*]C(=O)N([*])[*]" + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carboxamides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "41.99799" + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "primary carboxamide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carboxamides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:37622" + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:35355" + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carboxamides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) [label](http://www.w3.org/2000/01/rdf-schema#label) "carboxamide" + +- Class: [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [carbamoyl group](http://purl.obolibrary.org/obo/CHEBI_23004) + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) SubClassOf [primary amide](http://purl.obolibrary.org/obo/CHEBI_33256) + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) SubClassOf [organonitrogen compound](http://purl.obolibrary.org/obo/CHEBI_35352) + +- [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) SubClassOf [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) + + + +### carboxy group `http://purl.obolibrary.org/obo/CHEBI_46883` +#### Removed +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:FMT" + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carboxyl group" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "*C(=O)O" + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:46883" + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [label](http://www.w3.org/2000/01/rdf-schema#label) "carboxy group" + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "-C(O)OH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "44.99765" + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CHO2" + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "CARBOXY GROUP" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "-COOH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [mass](http://purl.obolibrary.org/obo/chebi/mass) "45.01744" + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "-CO2H" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:41420" + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23025" + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carboxy" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- Class: [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) + +- [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) SubClassOf [organyl group](http://purl.obolibrary.org/obo/CHEBI_33249) + + + +### carboxylic acid `http://purl.obolibrary.org/obo/CHEBI_33575` +#### Removed +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acidos carboxilicos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acido carboxilico" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acidos carboxilicos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Carbonsaeuren" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Carbonsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13428" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Karbonsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "RC(=O)OH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carboxylic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Carboxylic_acid" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CHO2R" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "OC([*])=O" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acide carboxylique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Carbonsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CHO2R" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [FORMULA](http://purl.obolibrary.org/obo/fbbt#FORMULA) + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23027" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "OC([*])=O" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [SMILES](http://purl.obolibrary.org/obo/fbbt#SMILES) + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13627" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid." + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33575" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [mass](http://purl.obolibrary.org/obo/chebi/mass) "45.01740" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acide carboxylique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Carbonsaeuren" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acides carboxyliques" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "44.99765" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "RC(=O)OH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acido carboxilico" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carboxylic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Karbonsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carboxylic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [label](http://www.w3.org/2000/01/rdf-schema#label) "carboxylic acid" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acides carboxyliques" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17147560" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18433345" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carboxylic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- Class: [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) SubClassOf [organic acid](http://purl.obolibrary.org/obo/CHEBI_64709) + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) SubClassOf [carbon oxoacid](http://purl.obolibrary.org/obo/CHEBI_35605) + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [carboxy group](http://purl.obolibrary.org/obo/CHEBI_46883) + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) + +- [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) SubClassOf [carbonyl compound](http://purl.obolibrary.org/obo/CHEBI_36586) + + + +### carboxylic acid anion `http://purl.obolibrary.org/obo/CHEBI_29067` +#### Removed +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carboxylic anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23026" + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) [label](http://www.w3.org/2000/01/rdf-schema#label) "carboxylic acid anion" + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated." + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13626" + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) [mass](http://purl.obolibrary.org/obo/chebi/mass) "44.00950" + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carboxylic acid anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[O-]C([*])=O" + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "43.98983" + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13945" + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CO2R" + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a carboxylate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:58657" + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:29067" + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) SubClassOf [oxoanion](http://purl.obolibrary.org/obo/CHEBI_35406) + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) + +- [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) SubClassOf [organic anion](http://purl.obolibrary.org/obo/CHEBI_25696) + + + +### carboxylic acid binding `http://purl.obolibrary.org/obo/GO_0031406` +#### Removed +- [carboxylic acid binding](http://purl.obolibrary.org/obo/GO_0031406) SubClassOf [anion binding](http://purl.obolibrary.org/obo/GO_0043168) + +#### Added +- [carboxylic acid binding](http://purl.obolibrary.org/obo/GO_0031406) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### carboxylic acid dianion `http://purl.obolibrary.org/obo/CHEBI_38716` +#### Removed +- [carboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_38716) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carboxylic acid dianions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_38716) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_38716) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carboxylic acid dianion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_38716) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any dianion containing at least one carboxy group." + +- [carboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_38716) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_38716) [label](http://www.w3.org/2000/01/rdf-schema#label) "carboxylic acid dianion" + +- [carboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_38716) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:38716" + +- Class: [carboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_38716) + +- [carboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_38716) SubClassOf [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) + + + +### carboxylic acid transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0046943` +#### Removed +- [carboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046943) SubClassOf [organic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008514) + +#### Added +- [carboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046943) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + +### carboxylic acid transport `http://purl.obolibrary.org/obo/GO_0046942` +#### Removed +- [carboxylic acid transport](http://purl.obolibrary.org/obo/GO_0046942) SubClassOf [organic anion transport](http://purl.obolibrary.org/obo/GO_0015711) + +#### Added +- [carboxylic acid transport](http://purl.obolibrary.org/obo/GO_0046942) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### carboxylic ester `http://purl.obolibrary.org/obo/CHEBI_33308` +#### Removed +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CO2R2" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [FORMULA](http://purl.obolibrary.org/obo/fbbt#FORMULA) + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "43.98983" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a carboxylic ester" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An ester of a carboxylic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [mass](http://purl.obolibrary.org/obo/chebi/mass) "44.010" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carboxylic acid esters" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23028" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Carboxylic ester" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carboxylic acid esters" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carboxylic esters" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [label](http://www.w3.org/2000/01/rdf-schema#label) "carboxylic ester" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:3408" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carboxylic ester" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt:" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ester" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Carboxylic ester" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carboxylic esters" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13204" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C02391" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[*]C(=O)O[*]" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33308" + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl." + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CO2R2" + +- Class: [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) SubClassOf [carbonyl compound](http://purl.obolibrary.org/obo/CHEBI_36586) + +- [carboxylic ester](http://purl.obolibrary.org/obo/CHEBI_33308) SubClassOf [ester](http://purl.obolibrary.org/obo/CHEBI_35701) + + + +### cardiac muscle cell (sensu Arthopoda) `http://purl.obolibrary.org/obo/CL_0000193` +#### Removed +- [cardiac muscle cell (sensu Arthopoda)](http://purl.obolibrary.org/obo/CL_0000193) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000466" + + + +### cardiac muscle myoblast `http://purl.obolibrary.org/obo/CL_0000513` +#### Removed +- [cardiac muscle myoblast](http://purl.obolibrary.org/obo/CL_0000513) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000714" + + + +### cardiac muscle of right atrium `http://purl.obolibrary.org/obo/UBERON_0003379` + +#### Added +- [cardiac muscle of right atrium](http://purl.obolibrary.org/obo/UBERON_0003379) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [cardiac muscle of right atrium](http://purl.obolibrary.org/obo/UBERON_0003379) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + +### cardiac muscle tissue `http://purl.obolibrary.org/obo/UBERON_0001133` +#### Removed +- [cardiac muscle tissue](http://purl.obolibrary.org/obo/UBERON_0001133) SubClassOf [striated muscle tissue](http://purl.obolibrary.org/obo/UBERON_0002036) + +#### Added +- [cardiac muscle tissue](http://purl.obolibrary.org/obo/UBERON_0001133) SubClassOf [visceral striated muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600006) + + +### cardiac muscle tissue of interventricular septum `http://purl.obolibrary.org/obo/UBERON_0003383` + +#### Added +- [cardiac muscle tissue of interventricular septum](http://purl.obolibrary.org/obo/UBERON_0003383) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + +- [cardiac muscle tissue of interventricular septum](http://purl.obolibrary.org/obo/UBERON_0003383) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + + +### cardiac septum cell `http://purl.obolibrary.org/obo/CL_2000022` +#### Removed +- [cardiac septum cell](http://purl.obolibrary.org/obo/CL_2000022) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### cardiac valve cell `http://purl.obolibrary.org/obo/CL_1000147` +#### Removed +- [cardiac valve cell](http://purl.obolibrary.org/obo/CL_1000147) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### cardiocyte `http://purl.obolibrary.org/obo/CL_0002494` +#### Removed +- [cardiocyte](http://purl.obolibrary.org/obo/CL_0002494) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### cardiotonic drug `http://purl.obolibrary.org/obo/CHEBI_38147` +#### Removed +- [cardiotonic drug](http://purl.obolibrary.org/obo/CHEBI_38147) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cardiotonic drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cardiotonic drug](http://purl.obolibrary.org/obo/CHEBI_38147) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [cardiotonic drug](http://purl.obolibrary.org/obo/CHEBI_38147) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [cardiotonic drug](http://purl.obolibrary.org/obo/CHEBI_38147) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A drug that has a strengthening effect on the heart or that can increase cardiac output." + +- [cardiotonic drug](http://purl.obolibrary.org/obo/CHEBI_38147) [label](http://www.w3.org/2000/01/rdf-schema#label) "cardiotonic drug" + +- [cardiotonic drug](http://purl.obolibrary.org/obo/CHEBI_38147) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:38147" + +- Class: [cardiotonic drug](http://purl.obolibrary.org/obo/CHEBI_38147) + +- [cardiotonic drug](http://purl.obolibrary.org/obo/CHEBI_38147) SubClassOf [cardiovascular drug](http://purl.obolibrary.org/obo/CHEBI_35554) + + + +### cardiovascular drug `http://purl.obolibrary.org/obo/CHEBI_35554` +#### Removed +- [cardiovascular drug](http://purl.obolibrary.org/obo/CHEBI_35554) [label](http://www.w3.org/2000/01/rdf-schema#label) "cardiovascular drug" + +- [cardiovascular drug](http://purl.obolibrary.org/obo/CHEBI_35554) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [cardiovascular drug](http://purl.obolibrary.org/obo/CHEBI_35554) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cardiovascular drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cardiovascular drug](http://purl.obolibrary.org/obo/CHEBI_35554) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [cardiovascular drug](http://purl.obolibrary.org/obo/CHEBI_35554) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume." + +- [cardiovascular drug](http://purl.obolibrary.org/obo/CHEBI_35554) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cardiovascular agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cardiovascular drug](http://purl.obolibrary.org/obo/CHEBI_35554) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35554" + +- Class: [cardiovascular drug](http://purl.obolibrary.org/obo/CHEBI_35554) + +- [cardiovascular drug](http://purl.obolibrary.org/obo/CHEBI_35554) SubClassOf [drug](http://purl.obolibrary.org/obo/CHEBI_23888) + + + +### catalyst `http://purl.obolibrary.org/obo/CHEBI_35223` +#### Removed +- [catalyst](http://purl.obolibrary.org/obo/CHEBI_35223) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction." + +- [catalyst](http://purl.obolibrary.org/obo/CHEBI_35223) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "catalyseur" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [catalyst](http://purl.obolibrary.org/obo/CHEBI_35223) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "catalyst" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [catalyst](http://purl.obolibrary.org/obo/CHEBI_35223) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "catalizador" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [catalyst](http://purl.obolibrary.org/obo/CHEBI_35223) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Katalysator" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [catalyst](http://purl.obolibrary.org/obo/CHEBI_35223) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35223" + +- [catalyst](http://purl.obolibrary.org/obo/CHEBI_35223) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [catalyst](http://purl.obolibrary.org/obo/CHEBI_35223) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [catalyst](http://purl.obolibrary.org/obo/CHEBI_35223) [label](http://www.w3.org/2000/01/rdf-schema#label) "catalyst" + +- Class: [catalyst](http://purl.obolibrary.org/obo/CHEBI_35223) + +- [catalyst](http://purl.obolibrary.org/obo/CHEBI_35223) SubClassOf [chemical role](http://purl.obolibrary.org/obo/CHEBI_51086) + + + +### catalytic activity, acting on DNA `http://purl.obolibrary.org/obo/GO_0140097` +#### Removed +- [catalytic activity, acting on DNA](http://purl.obolibrary.org/obo/GO_0140097) SubClassOf [catalytic activity, acting on a nucleic acid](http://purl.obolibrary.org/obo/GO_0140640) + +#### Added +- [catalytic activity, acting on DNA](http://purl.obolibrary.org/obo/GO_0140097) SubClassOf [catalytic activity](http://purl.obolibrary.org/obo/GO_0003824) + + +### catalytic activity, acting on RNA `http://purl.obolibrary.org/obo/GO_0140098` +#### Removed +- [catalytic activity, acting on RNA](http://purl.obolibrary.org/obo/GO_0140098) SubClassOf [catalytic activity, acting on a nucleic acid](http://purl.obolibrary.org/obo/GO_0140640) + +#### Added +- [catalytic activity, acting on RNA](http://purl.obolibrary.org/obo/GO_0140098) SubClassOf [catalytic activity](http://purl.obolibrary.org/obo/GO_0003824) + + +### catalytic activity, acting on a glycoprotein `http://purl.obolibrary.org/obo/GO_0140103` +#### Removed +- [catalytic activity, acting on a glycoprotein](http://purl.obolibrary.org/obo/GO_0140103) SubClassOf [catalytic activity, acting on a protein](http://purl.obolibrary.org/obo/GO_0140096) + +#### Added +- [catalytic activity, acting on a glycoprotein](http://purl.obolibrary.org/obo/GO_0140103) SubClassOf [catalytic activity](http://purl.obolibrary.org/obo/GO_0003824) + + +### catechol-containing compound biosynthetic process `http://purl.obolibrary.org/obo/GO_0009713` +#### Removed +- [catechol-containing compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0009713) SubClassOf [phenol-containing compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0046189) + +#### Added +- [catechol-containing compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0009713) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### catechol-containing compound catabolic process `http://purl.obolibrary.org/obo/GO_0019614` +#### Removed +- [catechol-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0019614) SubClassOf [phenol-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0019336) + +#### Added +- [catechol-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0019614) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### catecholamine `http://purl.obolibrary.org/obo/CHEBI_33567` +#### Removed +- [catecholamine](http://purl.obolibrary.org/obo/CHEBI_33567) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [catecholamine](http://purl.obolibrary.org/obo/CHEBI_33567) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "catecholamines" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [catecholamine](http://purl.obolibrary.org/obo/CHEBI_33567) [mass](http://purl.obolibrary.org/obo/chebi/mass) "151.163" + +- [catecholamine](http://purl.obolibrary.org/obo/CHEBI_33567) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C02012" + +- [catecholamine](http://purl.obolibrary.org/obo/CHEBI_33567) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "151.06333" + +- [catecholamine](http://purl.obolibrary.org/obo/CHEBI_33567) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [catecholamine](http://purl.obolibrary.org/obo/CHEBI_33567) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Catecholamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [catecholamine](http://purl.obolibrary.org/obo/CHEBI_33567) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:3468" + +- [catecholamine](http://purl.obolibrary.org/obo/CHEBI_33567) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23056" + +- [catecholamine](http://purl.obolibrary.org/obo/CHEBI_33567) [label](http://www.w3.org/2000/01/rdf-schema#label) "catecholamine" + +- [catecholamine](http://purl.obolibrary.org/obo/CHEBI_33567) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C8H9NO2R2" + +- [catecholamine](http://purl.obolibrary.org/obo/CHEBI_33567) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "catecholamines" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [catecholamine](http://purl.obolibrary.org/obo/CHEBI_33567) SubClassOf [catechols](http://purl.obolibrary.org/obo/CHEBI_33566) + +- [catecholamine](http://purl.obolibrary.org/obo/CHEBI_33567) SubClassOf [monoamine molecular messenger](http://purl.obolibrary.org/obo/CHEBI_25375) + + + +### catecholamine binding `http://purl.obolibrary.org/obo/GO_1901338` +#### Removed +- [catecholamine binding](http://purl.obolibrary.org/obo/GO_1901338) SubClassOf [organic cyclic compound binding](http://purl.obolibrary.org/obo/GO_0097159) + +#### Added +- [catecholamine binding](http://purl.obolibrary.org/obo/GO_1901338) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### catecholamine biosynthetic process `http://purl.obolibrary.org/obo/GO_0042423` +#### Removed +- [catecholamine biosynthetic process](http://purl.obolibrary.org/obo/GO_0042423) SubClassOf [catechol-containing compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0009713) + + + +### catecholamine catabolic process `http://purl.obolibrary.org/obo/GO_0042424` +#### Removed +- [catecholamine catabolic process](http://purl.obolibrary.org/obo/GO_0042424) SubClassOf [catechol-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0019614) + + + +### catecholamine transport `http://purl.obolibrary.org/obo/GO_0051937` +#### Removed +- [catecholamine transport](http://purl.obolibrary.org/obo/GO_0051937) SubClassOf [monoamine transport](http://purl.obolibrary.org/obo/GO_0015844) + +- [catecholamine transport](http://purl.obolibrary.org/obo/GO_0051937) SubClassOf [organic hydroxy compound transport](http://purl.obolibrary.org/obo/GO_0015850) + +#### Added +- [catecholamine transport](http://purl.obolibrary.org/obo/GO_0051937) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### catecholamine uptake `http://purl.obolibrary.org/obo/GO_0090493` +#### Removed +- [catecholamine uptake](http://purl.obolibrary.org/obo/GO_0090493) SubClassOf [import into cell](http://purl.obolibrary.org/obo/GO_0098657) + +#### Added +- [catecholamine uptake](http://purl.obolibrary.org/obo/GO_0090493) SubClassOf [has target end location](http://purl.obolibrary.org/obo/RO_0002339) some [intracellular anatomical structure](http://purl.obolibrary.org/obo/GO_0005622) + +- [catecholamine uptake](http://purl.obolibrary.org/obo/GO_0090493) SubClassOf [has target start location](http://purl.obolibrary.org/obo/RO_0002338) some [extracellular region](http://purl.obolibrary.org/obo/GO_0005576) + + +### catechols `http://purl.obolibrary.org/obo/CHEBI_33566` +#### Removed +- [catechols](http://purl.obolibrary.org/obo/CHEBI_33566) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [catechols](http://purl.obolibrary.org/obo/CHEBI_33566) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:134187" + +- [catechols](http://purl.obolibrary.org/obo/CHEBI_33566) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [catechols](http://purl.obolibrary.org/obo/CHEBI_33566) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "106.00548" + +- [catechols](http://purl.obolibrary.org/obo/CHEBI_33566) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C6H2O2R4" + +- [catechols](http://purl.obolibrary.org/obo/CHEBI_33566) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C15571" + +- [catechols](http://purl.obolibrary.org/obo/CHEBI_33566) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "OC1=C(O)C(*)=C(*)C(*)=C1*" + +- [catechols](http://purl.obolibrary.org/obo/CHEBI_33566) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a catechol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [catechols](http://purl.obolibrary.org/obo/CHEBI_33566) [label](http://www.w3.org/2000/01/rdf-schema#label) "catechols" + +- [catechols](http://purl.obolibrary.org/obo/CHEBI_33566) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any compound containing an o-diphenol component." + +- [catechols](http://purl.obolibrary.org/obo/CHEBI_33566) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13628" + +- [catechols](http://purl.obolibrary.org/obo/CHEBI_33566) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "benzene-1,2-diols" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [catechols](http://purl.obolibrary.org/obo/CHEBI_33566) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:18862" + +- [catechols](http://purl.obolibrary.org/obo/CHEBI_33566) [mass](http://purl.obolibrary.org/obo/chebi/mass) "106.079" + +- [catechols](http://purl.obolibrary.org/obo/CHEBI_33566) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "1,2-benzenediols" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [catechols](http://purl.obolibrary.org/obo/CHEBI_33566) SubClassOf [benzenediols](http://purl.obolibrary.org/obo/CHEBI_33570) + + + +### cation `http://purl.obolibrary.org/obo/CHEBI_36916` +#### Removed +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cationes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [label](http://www.w3.org/2000/01/rdf-schema#label) "cation" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36916" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Kationen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23058" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Kationen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01373" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A monoatomic or polyatomic species having one or more elementary charges of the proton." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Kation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cationes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:3473" + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Kation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- Class: [cation](http://purl.obolibrary.org/obo/CHEBI_36916) + +- [cation](http://purl.obolibrary.org/obo/CHEBI_36916) SubClassOf [ion](http://purl.obolibrary.org/obo/CHEBI_24870) + + + +### cation binding `http://purl.obolibrary.org/obo/GO_0043169` +#### Removed +- [cation binding](http://purl.obolibrary.org/obo/GO_0043169) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [cation binding](http://purl.obolibrary.org/obo/GO_0043169) [label](http://www.w3.org/2000/01/rdf-schema#label) "cation binding" + +- [cation binding](http://purl.obolibrary.org/obo/GO_0043169) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to a cation, a charged atom or group of atoms with a net positive charge." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [cation binding](http://purl.obolibrary.org/obo/GO_0043169) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0043169" + +- Class: [cation binding](http://purl.obolibrary.org/obo/GO_0043169) + +- [cation binding](http://purl.obolibrary.org/obo/GO_0043169) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [cation](http://purl.obolibrary.org/obo/CHEBI_36916)) + +- [cation binding](http://purl.obolibrary.org/obo/GO_0043169) SubClassOf [ion binding](http://purl.obolibrary.org/obo/GO_0043167) + +- [cation binding](http://purl.obolibrary.org/obo/GO_0043169) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [cation](http://purl.obolibrary.org/obo/CHEBI_36916) + + + +### causal relation between entities `http://purl.obolibrary.org/obo/RO_0002506` +#### Removed +- [causal relation between entities](http://purl.obolibrary.org/obo/RO_0002506) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [causal relation between entities](http://purl.obolibrary.org/obo/RO_0002506) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### causal relation between material entity and a process `http://purl.obolibrary.org/obo/RO_0002595` +#### Removed +- [causal relation between material entity and a process](http://purl.obolibrary.org/obo/RO_0002595) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [causal relation between material entity and a process](http://purl.obolibrary.org/obo/RO_0002595) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### causal relation between processes `http://purl.obolibrary.org/obo/RO_0002501` +#### Removed +- [causal relation between processes](http://purl.obolibrary.org/obo/RO_0002501) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [causal relation between processes](http://purl.obolibrary.org/obo/RO_0002501) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### causally downstream of `http://purl.obolibrary.org/obo/RO_0002404` +#### Removed +- [causally downstream of](http://purl.obolibrary.org/obo/RO_0002404) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [causally downstream of](http://purl.obolibrary.org/obo/RO_0002404) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### causally downstream of or within `http://purl.obolibrary.org/obo/RO_0002427` +#### Removed +- [causally downstream of or within](http://purl.obolibrary.org/obo/RO_0002427) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [causally downstream of or within](http://purl.obolibrary.org/obo/RO_0002427) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### causally influenced by `http://purl.obolibrary.org/obo/RO_0002559` +#### Removed +- [causally influenced by](http://purl.obolibrary.org/obo/RO_0002559) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [causally influenced by](http://purl.obolibrary.org/obo/RO_0002559) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### causally influences `http://purl.obolibrary.org/obo/RO_0002566` +#### Removed +- [causally influences](http://purl.obolibrary.org/obo/RO_0002566) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +- [causally influences](http://purl.obolibrary.org/obo/RO_0002566) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Vasundra Touré" + +#### Added +- [causally influences](http://purl.obolibrary.org/obo/RO_0002566) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0003-4639-4431](https://orcid.org/0000-0003-4639-4431) + +- [causally influences](http://purl.obolibrary.org/obo/RO_0002566) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### causally related to `http://purl.obolibrary.org/obo/RO_0002410` +#### Removed +- [causally related to](http://purl.obolibrary.org/obo/RO_0002410) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [causally related to](http://purl.obolibrary.org/obo/RO_0002410) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### causally upstream of `http://purl.obolibrary.org/obo/RO_0002411` +#### Removed +- [causally upstream of](http://purl.obolibrary.org/obo/RO_0002411) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [causally upstream of](http://purl.obolibrary.org/obo/RO_0002411) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### causally upstream of or within `http://purl.obolibrary.org/obo/RO_0002418` +#### Removed +- [causally upstream of or within](http://purl.obolibrary.org/obo/RO_0002418) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [causally upstream of or within](http://purl.obolibrary.org/obo/RO_0002418) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### causally upstream of or within, negative effect `http://purl.obolibrary.org/obo/RO_0004046` +#### Removed +- [causally upstream of or within, negative effect](http://purl.obolibrary.org/obo/RO_0004046) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "cjm" + +#### Added +- [causally upstream of or within, negative effect](http://purl.obolibrary.org/obo/RO_0004046) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### causally upstream of or within, positive effect `http://purl.obolibrary.org/obo/RO_0004047` +#### Removed +- [causally upstream of or within, positive effect](http://purl.obolibrary.org/obo/RO_0004047) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "cjm" + +#### Added +- [causally upstream of or within, positive effect](http://purl.obolibrary.org/obo/RO_0004047) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### causally upstream of, negative effect `http://purl.obolibrary.org/obo/RO_0002305` +#### Removed +- [causally upstream of, negative effect](http://purl.obolibrary.org/obo/RO_0002305) [creator](http://purl.org/dc/terms/creator) "cjm" + +#### Added +- [causally upstream of, negative effect](http://purl.obolibrary.org/obo/RO_0002305) [creator](http://purl.org/dc/terms/creator) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### causally upstream of, positive effect `http://purl.obolibrary.org/obo/RO_0002304` +#### Removed +- [causally upstream of, positive effect](http://purl.obolibrary.org/obo/RO_0002304) [creator](http://purl.org/dc/terms/creator) "cjm" + +#### Added +- [causally upstream of, positive effect](http://purl.obolibrary.org/obo/RO_0002304) [creator](http://purl.org/dc/terms/creator) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### cell `http://purl.obolibrary.org/obo/CL_0000000` + +#### Added +- [cell](http://purl.obolibrary.org/obo/CL_0000000) SubClassOf [anatomical structure](http://purl.obolibrary.org/obo/UBERON_0000061) + + +### cell death `http://purl.obolibrary.org/obo/GO_0008219` +#### Removed +- [cell death](http://purl.obolibrary.org/obo/GO_0008219) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_chembl](http://purl.obolibrary.org/obo/go#goslim_chembl) + +- [cell death](http://purl.obolibrary.org/obo/GO_0008219) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_drosophila](http://purl.obolibrary.org/obo/go#goslim_drosophila) + +- [cell death](http://purl.obolibrary.org/obo/GO_0008219) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_plant](http://purl.obolibrary.org/obo/go#goslim_plant) + +- [cell death](http://purl.obolibrary.org/obo/GO_0008219) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_agr](http://purl.obolibrary.org/obo/go#goslim_agr) + +- [cell death](http://purl.obolibrary.org/obo/GO_0008219) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_mouse](http://purl.obolibrary.org/obo/go#goslim_mouse) + + + +### cell development `http://purl.obolibrary.org/obo/GO_0048468` +#### Removed +- [cell development](http://purl.obolibrary.org/obo/GO_0048468) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +#### Added +- [cell development](http://purl.obolibrary.org/obo/GO_0048468) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24390"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [cell development](http://purl.obolibrary.org/obo/GO_0048468) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + + +### cell differentiation `http://purl.obolibrary.org/obo/GO_0030154` +#### Removed +- [cell differentiation](http://purl.obolibrary.org/obo/GO_0030154) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +#### Added +- [cell differentiation](http://purl.obolibrary.org/obo/GO_0030154) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [cell differentiation](http://purl.obolibrary.org/obo/GO_0030154) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24390"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### cell fate commitment `http://purl.obolibrary.org/obo/GO_0045165` +#### Removed +- [cell fate commitment](http://purl.obolibrary.org/obo/GO_0045165) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0716731185" + +#### Added +- [cell fate commitment](http://purl.obolibrary.org/obo/GO_0045165) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24390"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [cell fate commitment](http://purl.obolibrary.org/obo/GO_0045165) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0716731185" + + +### cell maturation `http://purl.obolibrary.org/obo/GO_0048469` +#### Removed +- [cell maturation](http://purl.obolibrary.org/obo/GO_0048469) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +#### Added +- [cell maturation](http://purl.obolibrary.org/obo/GO_0048469) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [cell maturation](http://purl.obolibrary.org/obo/GO_0048469) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24390"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### cell migration `http://purl.obolibrary.org/obo/GO_0016477` +#### Removed +- [cell migration](http://purl.obolibrary.org/obo/GO_0016477) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ems" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:cjm" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pf" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cell_migration" + +#### Added +- [cell migration](http://purl.obolibrary.org/obo/GO_0016477) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ems" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:cjm" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pf" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cell_migration" + +- [cell migration](http://purl.obolibrary.org/obo/GO_0016477) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24787"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### cell of skeletal muscle `http://purl.obolibrary.org/obo/CL_0000188` +#### Removed +- [cell of skeletal muscle](http://purl.obolibrary.org/obo/CL_0000188) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### cell periphery `http://purl.obolibrary.org/obo/GO_0071944` +#### Removed +- [cell periphery](http://purl.obolibrary.org/obo/GO_0071944) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +#### Added +- [cell periphery](http://purl.obolibrary.org/obo/GO_0071944) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pdt" + + +### cellular alkane metabolic process `http://purl.obolibrary.org/obo/GO_0043446` +#### Removed +- [cellular alkane metabolic process](http://purl.obolibrary.org/obo/GO_0043446) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular alkane metabolic process" + +- [cellular alkane metabolic process](http://purl.obolibrary.org/obo/GO_0043446) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkane metabolism" + +- [cellular alkane metabolic process](http://purl.obolibrary.org/obo/GO_0043446) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0043446" + +- [cellular alkane metabolic process](http://purl.obolibrary.org/obo/GO_0043446) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_pir](http://purl.obolibrary.org/obo/go#goslim_pir) + +- [cellular alkane metabolic process](http://purl.obolibrary.org/obo/GO_0043446) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, as carried out by individual cells." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Alkane" + +- [cellular alkane metabolic process](http://purl.obolibrary.org/obo/GO_0043446) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [cellular alkane metabolic process](http://purl.obolibrary.org/obo/GO_0043446) + +- [cellular alkane metabolic process](http://purl.obolibrary.org/obo/GO_0043446) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [alkane](http://purl.obolibrary.org/obo/CHEBI_18310)) + +- [cellular alkane metabolic process](http://purl.obolibrary.org/obo/GO_0043446) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) + +- [cellular alkane metabolic process](http://purl.obolibrary.org/obo/GO_0043446) SubClassOf [cellular metabolic process](http://purl.obolibrary.org/obo/GO_0044237) + +- [cellular alkane metabolic process](http://purl.obolibrary.org/obo/GO_0043446) SubClassOf [hydrocarbon metabolic process](http://purl.obolibrary.org/obo/GO_0120252) + + + +### cellular anatomical structure `http://purl.obolibrary.org/obo/CARO_0020003` +#### Removed +- [cellular anatomical structure](http://purl.obolibrary.org/obo/CARO_0020003) [created_by](ttp://www.geneontology.org/formats/oboInOwl#created_by) "dos" + +#### Added +- [cellular anatomical structure](http://purl.obolibrary.org/obo/CARO_0020003) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + + +### cellular carbohydrate biosynthetic process `http://purl.obolibrary.org/obo/GO_0034637` +#### Removed +- [cellular carbohydrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0034637) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular carbohydrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0034637) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0034637" + +- [cellular carbohydrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0034637) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular carbohydrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0034637) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular carbohydrate biosynthetic process" + +- Class: [cellular carbohydrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0034637) + +- [cellular carbohydrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0034637) SubClassOf [cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0044249) + +- [cellular carbohydrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0034637) SubClassOf [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262) + +- [cellular carbohydrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0034637) SubClassOf [carbohydrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0016051) + + + +### cellular carbohydrate catabolic process `http://purl.obolibrary.org/obo/GO_0044275` +#### Removed +- [cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0044275) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular carbohydrate catabolism" + +- [cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0044275) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0044275" + +- [cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0044275) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular carbohydrate breakdown" + +- [cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0044275) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0044275) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular carbohydrate catabolic process" + +- [cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0044275) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular carbohydrate degradation" + +- [cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0044275) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0044275) + +- [cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0044275) SubClassOf [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262) + +- [cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0044275) SubClassOf [carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0016052) + +- [cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0044275) SubClassOf [cellular catabolic process](http://purl.obolibrary.org/obo/GO_0044248) + + + +### cellular carbohydrate metabolic process `http://purl.obolibrary.org/obo/GO_0044262` +#### Removed +- [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0044262" + +- [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0006092" + +- [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular carbohydrate metabolism" + +- [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "main pathways of carbohydrate metabolic process" + +- [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular carbohydrate metabolic process" + +- [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "main pathways of carbohydrate metabolism" + +- Class: [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262) + +- [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262) SubClassOf [cellular metabolic process](http://purl.obolibrary.org/obo/GO_0044237) + +- [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262) SubClassOf [carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0005975) + + + +### cellular detoxification of aldehyde `http://purl.obolibrary.org/obo/GO_0110095` +#### Removed +- [cellular detoxification of aldehyde](http://purl.obolibrary.org/obo/GO_0110095) EquivalentTo [cellular detoxification](http://purl.obolibrary.org/obo/GO_1990748) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478)) + +- [cellular detoxification of aldehyde](http://purl.obolibrary.org/obo/GO_0110095) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) + +#### Added +- [cellular detoxification of aldehyde](http://purl.obolibrary.org/obo/GO_0110095) EquivalentTo [cellular detoxification](http://purl.obolibrary.org/obo/GO_1990748) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478)) + +- [cellular detoxification of aldehyde](http://purl.obolibrary.org/obo/GO_0110095) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) + + +### cellular detoxification of metal ion `http://purl.obolibrary.org/obo/GO_0140961` +#### Removed +- [cellular detoxification of metal ion](http://purl.obolibrary.org/obo/GO_0140961) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular detoxification of metal ion" + +- [cellular detoxification of metal ion](http://purl.obolibrary.org/obo/GO_0140961) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular detoxification of metal ion](http://purl.obolibrary.org/obo/GO_0140961) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular detoxification of metal cation" + +- [cellular detoxification of metal ion](http://purl.obolibrary.org/obo/GO_0140961) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process carried out at the cellular level that reduces or removes the toxicity of a metal ion." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:33046888" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:26729300" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:34442707" + +- [cellular detoxification of metal ion](http://purl.obolibrary.org/obo/GO_0140961) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2022-12-07T15:35:18Z" + +- [cellular detoxification of metal ion](http://purl.obolibrary.org/obo/GO_0140961) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0140961" + +- [cellular detoxification of metal ion](http://purl.obolibrary.org/obo/GO_0140961) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "pg" + +- Class: [cellular detoxification of metal ion](http://purl.obolibrary.org/obo/GO_0140961) + +- [cellular detoxification of metal ion](http://purl.obolibrary.org/obo/GO_0140961) EquivalentTo [cellular detoxification](http://purl.obolibrary.org/obo/GO_1990748) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213)) + +- [cellular detoxification of metal ion](http://purl.obolibrary.org/obo/GO_0140961) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) + +- [cellular detoxification of metal ion](http://purl.obolibrary.org/obo/GO_0140961) SubClassOf [cellular detoxification](http://purl.obolibrary.org/obo/GO_1990748) + +- [cellular detoxification of metal ion](http://purl.obolibrary.org/obo/GO_0140961) SubClassOf [detoxification of inorganic compound](http://purl.obolibrary.org/obo/GO_0061687) + + + +### cellular glucan metabolic process `http://purl.obolibrary.org/obo/GO_0006073` +#### Removed +- [cellular glucan metabolic process](http://purl.obolibrary.org/obo/GO_0006073) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular glucan metabolic process](http://purl.obolibrary.org/obo/GO_0006073) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular glucan metabolism" + +- [cellular glucan metabolic process](http://purl.obolibrary.org/obo/GO_0006073) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues, occurring at the level of an individual cell." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198547684" + +- [cellular glucan metabolic process](http://purl.obolibrary.org/obo/GO_0006073) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular glucan metabolic process" + +- [cellular glucan metabolic process](http://purl.obolibrary.org/obo/GO_0006073) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006073" + +- Class: [cellular glucan metabolic process](http://purl.obolibrary.org/obo/GO_0006073) + +- [cellular glucan metabolic process](http://purl.obolibrary.org/obo/GO_0006073) SubClassOf [cellular polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0044264) + +- [cellular glucan metabolic process](http://purl.obolibrary.org/obo/GO_0006073) SubClassOf [glucan metabolic process](http://purl.obolibrary.org/obo/GO_0044042) + + + +### cellular lipid catabolic process `http://purl.obolibrary.org/obo/GO_0044242` +#### Removed +- [cellular lipid catabolic process](http://purl.obolibrary.org/obo/GO_0044242) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular lipid catabolic process](http://purl.obolibrary.org/obo/GO_0044242) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [cellular lipid catabolic process](http://purl.obolibrary.org/obo/GO_0044242) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular lipid degradation" + +- [cellular lipid catabolic process](http://purl.obolibrary.org/obo/GO_0044242) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular lipid catabolism" + +- [cellular lipid catabolic process](http://purl.obolibrary.org/obo/GO_0044242) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular lipid catabolic process" + +- [cellular lipid catabolic process](http://purl.obolibrary.org/obo/GO_0044242) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0044242" + +- [cellular lipid catabolic process](http://purl.obolibrary.org/obo/GO_0044242) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular lipid breakdown" + +- Class: [cellular lipid catabolic process](http://purl.obolibrary.org/obo/GO_0044242) + +- [cellular lipid catabolic process](http://purl.obolibrary.org/obo/GO_0044242) SubClassOf [cellular catabolic process](http://purl.obolibrary.org/obo/GO_0044248) + +- [cellular lipid catabolic process](http://purl.obolibrary.org/obo/GO_0044242) SubClassOf [cellular lipid metabolic process](http://purl.obolibrary.org/obo/GO_0044255) + +- [cellular lipid catabolic process](http://purl.obolibrary.org/obo/GO_0044242) SubClassOf [lipid catabolic process](http://purl.obolibrary.org/obo/GO_0016042) + + + +### cellular lipid metabolic process `http://purl.obolibrary.org/obo/GO_0044255` +#### Removed +- [cellular lipid metabolic process](http://purl.obolibrary.org/obo/GO_0044255) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving lipids, as carried out by individual cells." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [cellular lipid metabolic process](http://purl.obolibrary.org/obo/GO_0044255) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular lipid metabolic process" + +- [cellular lipid metabolic process](http://purl.obolibrary.org/obo/GO_0044255) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular lipid metabolic process](http://purl.obolibrary.org/obo/GO_0044255) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0044255" + +- [cellular lipid metabolic process](http://purl.obolibrary.org/obo/GO_0044255) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular lipid metabolism" + +- [cellular lipid metabolic process](http://purl.obolibrary.org/obo/GO_0044255) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_pir](http://purl.obolibrary.org/obo/go#goslim_pir) + +- Class: [cellular lipid metabolic process](http://purl.obolibrary.org/obo/GO_0044255) + +- [cellular lipid metabolic process](http://purl.obolibrary.org/obo/GO_0044255) SubClassOf [cellular metabolic process](http://purl.obolibrary.org/obo/GO_0044237) + +- [cellular lipid metabolic process](http://purl.obolibrary.org/obo/GO_0044255) SubClassOf [lipid metabolic process](http://purl.obolibrary.org/obo/GO_0006629) + + + +### cellular macromolecule biosynthetic process `http://purl.obolibrary.org/obo/GO_0034645` +#### Removed +- [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0034645" + +- [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular macromolecule anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular biopolymer biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_chebi_dec09" + +- [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular macromolecule biosynthetic process" + +- [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0034961" + +- [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular macromolecule biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular macromolecule synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular macromolecule formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- Class: [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) + +- [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) SubClassOf [macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0009059) + +- [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) SubClassOf [cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0044249) + +- [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) SubClassOf [cellular macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0044260) + + + +### cellular macromolecule catabolic process `http://purl.obolibrary.org/obo/GO_0044265` +#### Removed +- [cellular macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0044265) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular macromolecule breakdown" + +- [cellular macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0044265) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [cellular macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0044265) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular macromolecule catabolic process" + +- [cellular macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0044265) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0044265" + +- [cellular macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0044265) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0034962" + +- [cellular macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0044265) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular macromolecule degradation" + +- [cellular macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0044265) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular macromolecule catabolism" + +- [cellular macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0044265) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular biopolymer catabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_chebi_dec09" + +- [cellular macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0044265) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [cellular macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0044265) + +- [cellular macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0044265) SubClassOf [macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0009057) + +- [cellular macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0044265) SubClassOf [cellular catabolic process](http://purl.obolibrary.org/obo/GO_0044248) + +- [cellular macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0044265) SubClassOf [cellular macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0044260) + + + +### cellular macromolecule metabolic process `http://purl.obolibrary.org/obo/GO_0044260` +#### Removed +- [cellular macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0044260) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0034960" + +- [cellular macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0044260) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular macromolecule metabolic process" + +- [cellular macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0044260) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0044260" + +- [cellular macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0044260) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0044260) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular biopolymer metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_chebi_dec09" + +- [cellular macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0044260) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0044260) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular macromolecule metabolism" + +- Class: [cellular macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0044260) + +- [cellular macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0044260) SubClassOf [macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0043170) + +- [cellular macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0044260) SubClassOf [cellular metabolic process](http://purl.obolibrary.org/obo/GO_0044237) + + + +### cellular metabolic process `http://purl.obolibrary.org/obo/GO_0044237` + +#### Added +- [cellular metabolic process](http://purl.obolibrary.org/obo/GO_0044237) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term." + + +### cellular modified amino acid biosynthetic process `http://purl.obolibrary.org/obo/GO_0042398` +#### Removed +- [cellular modified amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042398) SubClassOf [organonitrogen compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901566) + +#### Added +- [cellular modified amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042398) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### cellular modified amino acid catabolic process `http://purl.obolibrary.org/obo/GO_0042219` +#### Removed +- [cellular modified amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0042219) SubClassOf [organonitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_1901565) + +#### Added +- [cellular modified amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0042219) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### cellular organism `http://purl.obolibrary.org/obo/CARO_0010004` +#### Removed +- [cellular organism](http://purl.obolibrary.org/obo/CARO_0010004) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "mah" + +#### Added +- [cellular organism](http://purl.obolibrary.org/obo/CARO_0010004) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0001-9114-8737](https://orcid.org/0000-0001-9114-8737) + + +### cellular polysaccharide biosynthetic process `http://purl.obolibrary.org/obo/GO_0033692` +#### Removed +- [cellular polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0033692) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular polysaccharide biosynthetic process" + +- [cellular polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0033692) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular glycan biosynthesis" + +- [cellular polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0033692) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0033692) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, occurring at the level of an individual cell." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [cellular polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0033692) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular polysaccharide synthesis" + +- [cellular polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0033692) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular polysaccharide biosynthesis" + +- [cellular polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0033692) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular polysaccharide anabolism" + +- [cellular polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0033692) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular glycan biosynthetic process" + +- [cellular polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0033692) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular polysaccharide formation" + +- [cellular polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0033692) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0033692" + +- Class: [cellular polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0033692) + +- [cellular polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0033692) SubClassOf [polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0000271) + +- [cellular polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0033692) SubClassOf [cellular polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0044264) + +- [cellular polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0033692) SubClassOf [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) + +- [cellular polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0033692) SubClassOf [cellular carbohydrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0034637) + + + +### cellular polysaccharide catabolic process `http://purl.obolibrary.org/obo/GO_0044247` +#### Removed +- [cellular polysaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0044247) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular polysaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0044247) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular polysaccharide catabolism" + +- [cellular polysaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0044247) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular polysaccharide breakdown" + +- [cellular polysaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0044247) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, as carried out by individual cells." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [cellular polysaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0044247) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular polysaccharide catabolic process" + +- [cellular polysaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0044247) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular polysaccharide degradation" + +- [cellular polysaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0044247) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0044247" + +- Class: [cellular polysaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0044247) + +- [cellular polysaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0044247) SubClassOf [cellular polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0044264) + +- [cellular polysaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0044247) SubClassOf [polysaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0000272) + +- [cellular polysaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0044247) SubClassOf [cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0044275) + + + +### cellular polysaccharide metabolic process `http://purl.obolibrary.org/obo/GO_0044264` +#### Removed +- [cellular polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0044264) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular polysaccharide metabolism" + +- [cellular polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0044264) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular glycan metabolism" + +- [cellular polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0044264) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0044264" + +- [cellular polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0044264) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0044264) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, as carried out by individual cells." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [cellular polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0044264) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular polysaccharide metabolic process" + +- [cellular polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0044264) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular glycan metabolic process" + +- Class: [cellular polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0044264) + +- [cellular polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0044264) SubClassOf [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262) + +- [cellular polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0044264) SubClassOf [polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005976) + +- [cellular polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0044264) SubClassOf [cellular macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0044260) + + + +### cellular process `http://purl.obolibrary.org/obo/GO_0009987` + +#### Added +- [cellular process](http://purl.obolibrary.org/obo/GO_0009987) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term." + + +### cellular response to L-glutamate `http://purl.obolibrary.org/obo/GO_1905232` + +#### Added +- [cellular response to L-glutamate](http://purl.obolibrary.org/obo/GO_1905232) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to L-glutamate" + +- [cellular response to L-glutamate](http://purl.obolibrary.org/obo/GO_1905232) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cellular response to L-glutamate(1-)" + +- [cellular response to L-glutamate](http://purl.obolibrary.org/obo/GO_1905232) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular response to L-glutamate](http://purl.obolibrary.org/obo/GO_1905232) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1905232" + +- [cellular response to L-glutamate](http://purl.obolibrary.org/obo/GO_1905232) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25962137" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000071" + +- [cellular response to L-glutamate](http://purl.obolibrary.org/obo/GO_1905232) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "sl" + +- [cellular response to L-glutamate](http://purl.obolibrary.org/obo/GO_1905232) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2016-06-07T17:30:08Z" + +- Class: [cellular response to L-glutamate](http://purl.obolibrary.org/obo/GO_1905232) + +- [cellular response to L-glutamate](http://purl.obolibrary.org/obo/GO_1905232) EquivalentTo [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [CHEBI_29985](http://purl.obolibrary.org/obo/CHEBI_29985)) + +- [cellular response to L-glutamate](http://purl.obolibrary.org/obo/GO_1905232) SubClassOf [response to L-glutamate](http://purl.obolibrary.org/obo/GO_1902065) + +- [cellular response to L-glutamate](http://purl.obolibrary.org/obo/GO_1905232) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to acetate `http://purl.obolibrary.org/obo/GO_0071311` +#### Removed +- [cellular response to acetate](http://purl.obolibrary.org/obo/GO_0071311) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0071311" + +- [cellular response to acetate](http://purl.obolibrary.org/obo/GO_0071311) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular response to acetate](http://purl.obolibrary.org/obo/GO_0071311) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- [cellular response to acetate](http://purl.obolibrary.org/obo/GO_0071311) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular response to acetate](http://purl.obolibrary.org/obo/GO_0071311) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to acetate" + +- [cellular response to acetate](http://purl.obolibrary.org/obo/GO_0071311) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2009-12-10T04:48:16Z" + +- Class: [cellular response to acetate](http://purl.obolibrary.org/obo/GO_0071311) + +- [cellular response to acetate](http://purl.obolibrary.org/obo/GO_0071311) EquivalentTo [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089)) + +- [cellular response to acetate](http://purl.obolibrary.org/obo/GO_0071311) SubClassOf [cellular response to organic substance](http://purl.obolibrary.org/obo/GO_0071310) + +- [cellular response to acetate](http://purl.obolibrary.org/obo/GO_0071311) SubClassOf [cellular response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901701) + +- [cellular response to acetate](http://purl.obolibrary.org/obo/GO_0071311) SubClassOf [response to acetate](http://purl.obolibrary.org/obo/GO_0010034) + + + +### cellular response to acetylcholine `http://purl.obolibrary.org/obo/GO_1905145` +#### Removed +- [cellular response to acetylcholine](http://purl.obolibrary.org/obo/GO_1905145) SubClassOf [cellular response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901699) + +- [cellular response to acetylcholine](http://purl.obolibrary.org/obo/GO_1905145) SubClassOf [cellular response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901701) + +#### Added +- [cellular response to acetylcholine](http://purl.obolibrary.org/obo/GO_1905145) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to alcohol `http://purl.obolibrary.org/obo/GO_0097306` +#### Removed +- [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to alcohol" + +- [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pr" + +- [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "pr" + +- [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-05-15T03:49:51Z" + +- [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0097306" + +- Class: [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306) + +- [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306) EquivalentTo [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879)) + +- [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306) SubClassOf [cellular response to organic substance](http://purl.obolibrary.org/obo/GO_0071310) + +- [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306) SubClassOf [cellular response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901701) + +- [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306) SubClassOf [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) + + + +### cellular response to aldehyde `http://purl.obolibrary.org/obo/GO_0110096` +#### Removed +- [cellular response to aldehyde](http://purl.obolibrary.org/obo/GO_0110096) SubClassOf [response to organic substance](http://purl.obolibrary.org/obo/GO_0010033) + +- [cellular response to aldehyde](http://purl.obolibrary.org/obo/GO_0110096) SubClassOf [cellular response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901701) + +#### Added +- [cellular response to aldehyde](http://purl.obolibrary.org/obo/GO_0110096) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to aldosterone `http://purl.obolibrary.org/obo/GO_1904045` +#### Removed +- [cellular response to aldosterone](http://purl.obolibrary.org/obo/GO_1904045) SubClassOf [cellular response to mineralocorticoid stimulus](http://purl.obolibrary.org/obo/GO_0071389) + +- [cellular response to aldosterone](http://purl.obolibrary.org/obo/GO_1904045) SubClassOf [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306) + +- [cellular response to aldosterone](http://purl.obolibrary.org/obo/GO_1904045) SubClassOf [cellular response to aldehyde](http://purl.obolibrary.org/obo/GO_0110096) + +- [cellular response to aldosterone](http://purl.obolibrary.org/obo/GO_1904045) SubClassOf [cellular response to ketone](http://purl.obolibrary.org/obo/GO_1901655) + +#### Added +- [cellular response to aldosterone](http://purl.obolibrary.org/obo/GO_1904045) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to alkaloid `http://purl.obolibrary.org/obo/GO_0071312` +#### Removed +- [cellular response to alkaloid](http://purl.obolibrary.org/obo/GO_0071312) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- [cellular response to alkaloid](http://purl.obolibrary.org/obo/GO_0071312) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular response to alkaloid](http://purl.obolibrary.org/obo/GO_0071312) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0071312" + +- [cellular response to alkaloid](http://purl.obolibrary.org/obo/GO_0071312) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular response to alkaloid](http://purl.obolibrary.org/obo/GO_0071312) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2009-12-10T04:50:58Z" + +- [cellular response to alkaloid](http://purl.obolibrary.org/obo/GO_0071312) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to alkaloid" + +- Class: [cellular response to alkaloid](http://purl.obolibrary.org/obo/GO_0071312) + +- [cellular response to alkaloid](http://purl.obolibrary.org/obo/GO_0071312) EquivalentTo [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315)) + +- [cellular response to alkaloid](http://purl.obolibrary.org/obo/GO_0071312) SubClassOf [response to alkaloid](http://purl.obolibrary.org/obo/GO_0043279) + +- [cellular response to alkaloid](http://purl.obolibrary.org/obo/GO_0071312) SubClassOf [cellular response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0071417) + + + +### cellular response to alkane `http://purl.obolibrary.org/obo/GO_1902779` +#### Removed +- [cellular response to alkane](http://purl.obolibrary.org/obo/GO_1902779) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22958739" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23826995" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000071" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [cellular response to alkane](http://purl.obolibrary.org/obo/GO_1902779) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to alkane" + +- [cellular response to alkane](http://purl.obolibrary.org/obo/GO_1902779) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [cellular response to alkane](http://purl.obolibrary.org/obo/GO_1902779) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-03-21T03:18:04Z" + +- [cellular response to alkane](http://purl.obolibrary.org/obo/GO_1902779) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular response to alkane](http://purl.obolibrary.org/obo/GO_1902779) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902779" + +- Class: [cellular response to alkane](http://purl.obolibrary.org/obo/GO_1902779) + +- [cellular response to alkane](http://purl.obolibrary.org/obo/GO_1902779) EquivalentTo [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [alkane](http://purl.obolibrary.org/obo/CHEBI_18310)) + +- [cellular response to alkane](http://purl.obolibrary.org/obo/GO_1902779) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + +- [cellular response to alkane](http://purl.obolibrary.org/obo/GO_1902779) SubClassOf [response to alkane](http://purl.obolibrary.org/obo/GO_1902778) + + + +### cellular response to amine stimulus `http://purl.obolibrary.org/obo/GO_0071418` +#### Removed +- [cellular response to amine stimulus](http://purl.obolibrary.org/obo/GO_0071418) SubClassOf [cellular response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0071417) + +#### Added +- [cellular response to amine stimulus](http://purl.obolibrary.org/obo/GO_0071418) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to amino acid stimulus `http://purl.obolibrary.org/obo/GO_0071230` +#### Removed +- [cellular response to amino acid stimulus](http://purl.obolibrary.org/obo/GO_0071230) SubClassOf [cellular response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901701) + +- [cellular response to amino acid stimulus](http://purl.obolibrary.org/obo/GO_0071230) SubClassOf [cellular response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0071417) + +#### Added +- [cellular response to amino acid stimulus](http://purl.obolibrary.org/obo/GO_0071230) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to ammonium ion `http://purl.obolibrary.org/obo/GO_0071242` +#### Removed +- [cellular response to ammonium ion](http://purl.obolibrary.org/obo/GO_0071242) SubClassOf [cellular response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901699) + +#### Added +- [cellular response to ammonium ion](http://purl.obolibrary.org/obo/GO_0071242) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to bile acid `http://purl.obolibrary.org/obo/GO_1903413` +#### Removed +- [cellular response to bile acid](http://purl.obolibrary.org/obo/GO_1903413) SubClassOf [cellular response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901701) + +- [cellular response to bile acid](http://purl.obolibrary.org/obo/GO_1903413) SubClassOf [cellular response to organic cyclic compound](http://purl.obolibrary.org/obo/GO_0071407) + +- [cellular response to bile acid](http://purl.obolibrary.org/obo/GO_1903413) SubClassOf [cellular response to lipid](http://purl.obolibrary.org/obo/GO_0071396) + +#### Added +- [cellular response to bile acid](http://purl.obolibrary.org/obo/GO_1903413) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to butyrate `http://purl.obolibrary.org/obo/GO_1903545` +#### Removed +- [cellular response to butyrate](http://purl.obolibrary.org/obo/GO_1903545) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-10-17T13:57:35Z" + +- [cellular response to butyrate](http://purl.obolibrary.org/obo/GO_1903545) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular response to butyrate](http://purl.obolibrary.org/obo/GO_1903545) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mr" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9734870" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000071" + +- [cellular response to butyrate](http://purl.obolibrary.org/obo/GO_1903545) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mr" + +- [cellular response to butyrate](http://purl.obolibrary.org/obo/GO_1903545) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1903545" + +- [cellular response to butyrate](http://purl.obolibrary.org/obo/GO_1903545) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to butyrate" + +- Class: [cellular response to butyrate](http://purl.obolibrary.org/obo/GO_1903545) + +- [cellular response to butyrate](http://purl.obolibrary.org/obo/GO_1903545) EquivalentTo [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968)) + +- [cellular response to butyrate](http://purl.obolibrary.org/obo/GO_1903545) SubClassOf [cellular response to fatty acid](http://purl.obolibrary.org/obo/GO_0071398) + +- [cellular response to butyrate](http://purl.obolibrary.org/obo/GO_1903545) SubClassOf [response to butyrate](http://purl.obolibrary.org/obo/GO_1903544) + + + +### cellular response to calcium ion `http://purl.obolibrary.org/obo/GO_0071277` +#### Removed +- [cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_0071277) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0071277" + +- [cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_0071277) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_0071277) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- [cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_0071277) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2009-12-10T03:55:01Z" + +- [cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_0071277) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular response to Ca2+ ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_0071277) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_0071277) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to calcium ion" + +- Class: [cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_0071277) + +- [cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_0071277) EquivalentTo [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [calcium ion](http://purl.obolibrary.org/obo/CHEBI_39124)) + +- [cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_0071277) SubClassOf [response to calcium ion](http://purl.obolibrary.org/obo/GO_0051592) + +- [cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_0071277) SubClassOf [cellular response to metal ion](http://purl.obolibrary.org/obo/GO_0071248) + + + +### cellular response to carbohydrate stimulus `http://purl.obolibrary.org/obo/GO_0071322` +#### Removed +- [cellular response to carbohydrate stimulus](http://purl.obolibrary.org/obo/GO_0071322) SubClassOf [cellular response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901701) + + + +### cellular response to catecholamine stimulus `http://purl.obolibrary.org/obo/GO_0071870` +#### Removed +- [cellular response to catecholamine stimulus](http://purl.obolibrary.org/obo/GO_0071870) SubClassOf [cellular response to monoamine stimulus](http://purl.obolibrary.org/obo/GO_0071868) + +- [cellular response to catecholamine stimulus](http://purl.obolibrary.org/obo/GO_0071870) SubClassOf [cellular response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901701) + +- [cellular response to catecholamine stimulus](http://purl.obolibrary.org/obo/GO_0071870) SubClassOf [cellular response to organic cyclic compound](http://purl.obolibrary.org/obo/GO_0071407) + +#### Added +- [cellular response to catecholamine stimulus](http://purl.obolibrary.org/obo/GO_0071870) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to chemical stress `http://purl.obolibrary.org/obo/GO_0062197` +#### Removed +- [cellular response to chemical stress](http://purl.obolibrary.org/obo/GO_0062197) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2019-12-10T14:42:03Z" + +- [cellular response to chemical stress](http://purl.obolibrary.org/obo/GO_0062197) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:26653712" + +- [cellular response to chemical stress](http://purl.obolibrary.org/obo/GO_0062197) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0062197" + +- [cellular response to chemical stress](http://purl.obolibrary.org/obo/GO_0062197) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "dph" + +- [cellular response to chemical stress](http://purl.obolibrary.org/obo/GO_0062197) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to chemical stress" + +- [cellular response to chemical stress](http://purl.obolibrary.org/obo/GO_0062197) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [cellular response to chemical stress](http://purl.obolibrary.org/obo/GO_0062197) + +- [cellular response to chemical stress](http://purl.obolibrary.org/obo/GO_0062197) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + +- [cellular response to chemical stress](http://purl.obolibrary.org/obo/GO_0062197) SubClassOf [cellular response to stress](http://purl.obolibrary.org/obo/GO_0033554) + + + +### cellular response to corticosteroid stimulus `http://purl.obolibrary.org/obo/GO_0071384` +#### Removed +- [cellular response to corticosteroid stimulus](http://purl.obolibrary.org/obo/GO_0071384) SubClassOf [response to corticosteroid](http://purl.obolibrary.org/obo/GO_0031960) + +- [cellular response to corticosteroid stimulus](http://purl.obolibrary.org/obo/GO_0071384) SubClassOf [cellular response to steroid hormone stimulus](http://purl.obolibrary.org/obo/GO_0071383) + +#### Added +- [cellular response to corticosteroid stimulus](http://purl.obolibrary.org/obo/GO_0071384) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to dopamine `http://purl.obolibrary.org/obo/GO_1903351` +#### Removed +- [cellular response to dopamine](http://purl.obolibrary.org/obo/GO_1903351) SubClassOf [cellular response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901699) + +#### Added +- [cellular response to dopamine](http://purl.obolibrary.org/obo/GO_1903351) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to epinephrine stimulus `http://purl.obolibrary.org/obo/GO_0071872` +#### Removed +- [cellular response to epinephrine stimulus](http://purl.obolibrary.org/obo/GO_0071872) SubClassOf [cellular response to catecholamine stimulus](http://purl.obolibrary.org/obo/GO_0071870) + +#### Added +- [cellular response to epinephrine stimulus](http://purl.obolibrary.org/obo/GO_0071872) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to estradiol stimulus `http://purl.obolibrary.org/obo/GO_0071392` +#### Removed +- [cellular response to estradiol stimulus](http://purl.obolibrary.org/obo/GO_0071392) SubClassOf [cellular response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901701) + +- [cellular response to estradiol stimulus](http://purl.obolibrary.org/obo/GO_0071392) SubClassOf [cellular response to organic cyclic compound](http://purl.obolibrary.org/obo/GO_0071407) + +- [cellular response to estradiol stimulus](http://purl.obolibrary.org/obo/GO_0071392) SubClassOf [cellular response to lipid](http://purl.obolibrary.org/obo/GO_0071396) + +#### Added +- [cellular response to estradiol stimulus](http://purl.obolibrary.org/obo/GO_0071392) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to fatty acid `http://purl.obolibrary.org/obo/GO_0071398` +#### Removed +- [cellular response to fatty acid](http://purl.obolibrary.org/obo/GO_0071398) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular response to fatty acid](http://purl.obolibrary.org/obo/GO_0071398) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- [cellular response to fatty acid](http://purl.obolibrary.org/obo/GO_0071398) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0071398" + +- [cellular response to fatty acid](http://purl.obolibrary.org/obo/GO_0071398) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular response to fatty acid](http://purl.obolibrary.org/obo/GO_0071398) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to fatty acid" + +- [cellular response to fatty acid](http://purl.obolibrary.org/obo/GO_0071398) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2009-12-11T04:39:56Z" + +- Class: [cellular response to fatty acid](http://purl.obolibrary.org/obo/GO_0071398) + +- [cellular response to fatty acid](http://purl.obolibrary.org/obo/GO_0071398) EquivalentTo [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868)) + +- [cellular response to fatty acid](http://purl.obolibrary.org/obo/GO_0071398) SubClassOf [cellular response to lipid](http://purl.obolibrary.org/obo/GO_0071396) + +- [cellular response to fatty acid](http://purl.obolibrary.org/obo/GO_0071398) SubClassOf [cellular response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901701) + +- [cellular response to fatty acid](http://purl.obolibrary.org/obo/GO_0071398) SubClassOf [response to fatty acid](http://purl.obolibrary.org/obo/GO_0070542) + + + +### cellular response to glucagon stimulus `http://purl.obolibrary.org/obo/GO_0071377` +#### Removed +- [cellular response to glucagon stimulus](http://purl.obolibrary.org/obo/GO_0071377) SubClassOf [cellular response to peptide hormone stimulus](http://purl.obolibrary.org/obo/GO_0071375) + +#### Added +- [cellular response to glucagon stimulus](http://purl.obolibrary.org/obo/GO_0071377) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to glucocorticoid stimulus `http://purl.obolibrary.org/obo/GO_0071385` +#### Removed +- [cellular response to glucocorticoid stimulus](http://purl.obolibrary.org/obo/GO_0071385) SubClassOf [cellular response to corticosteroid stimulus](http://purl.obolibrary.org/obo/GO_0071384) + +#### Added +- [cellular response to glucocorticoid stimulus](http://purl.obolibrary.org/obo/GO_0071385) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to glucose stimulus `http://purl.obolibrary.org/obo/GO_0071333` +#### Removed +- [cellular response to glucose stimulus](http://purl.obolibrary.org/obo/GO_0071333) SubClassOf [cellular response to hexose stimulus](http://purl.obolibrary.org/obo/GO_0071331) + +#### Added +- [cellular response to glucose stimulus](http://purl.obolibrary.org/obo/GO_0071333) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to glycoprotein `http://purl.obolibrary.org/obo/GO_1904588` +#### Removed +- [cellular response to glycoprotein](http://purl.obolibrary.org/obo/GO_1904588) SubClassOf [cellular response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901701) + +- [cellular response to glycoprotein](http://purl.obolibrary.org/obo/GO_1904588) SubClassOf [cellular response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0071417) + +#### Added +- [cellular response to glycoprotein](http://purl.obolibrary.org/obo/GO_1904588) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to hexose stimulus `http://purl.obolibrary.org/obo/GO_0071331` +#### Removed +- [cellular response to hexose stimulus](http://purl.obolibrary.org/obo/GO_0071331) SubClassOf [cellular response to monosaccharide stimulus](http://purl.obolibrary.org/obo/GO_0071326) + +#### Added +- [cellular response to hexose stimulus](http://purl.obolibrary.org/obo/GO_0071331) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to histamine `http://purl.obolibrary.org/obo/GO_0071420` +#### Removed +- [cellular response to histamine](http://purl.obolibrary.org/obo/GO_0071420) SubClassOf [cellular response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901699) + +#### Added +- [cellular response to histamine](http://purl.obolibrary.org/obo/GO_0071420) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to iron ion `http://purl.obolibrary.org/obo/GO_0071281` +#### Removed +- [cellular response to iron ion](http://purl.obolibrary.org/obo/GO_0071281) SubClassOf [cellular response to metal ion](http://purl.obolibrary.org/obo/GO_0071248) + +#### Added +- [cellular response to iron ion](http://purl.obolibrary.org/obo/GO_0071281) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to ketone `http://purl.obolibrary.org/obo/GO_1901655` +#### Removed +- [cellular response to ketone](http://purl.obolibrary.org/obo/GO_1901655) SubClassOf [cellular response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901701) + +#### Added +- [cellular response to ketone](http://purl.obolibrary.org/obo/GO_1901655) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to metal ion `http://purl.obolibrary.org/obo/GO_0071248` +#### Removed +- [cellular response to metal ion](http://purl.obolibrary.org/obo/GO_0071248) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to metal ion" + +- [cellular response to metal ion](http://purl.obolibrary.org/obo/GO_0071248) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0071248" + +- [cellular response to metal ion](http://purl.obolibrary.org/obo/GO_0071248) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "cellular response to heavy metal" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular response to metal ion](http://purl.obolibrary.org/obo/GO_0071248) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2009-12-03T02:46:31Z" + +- [cellular response to metal ion](http://purl.obolibrary.org/obo/GO_0071248) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular response to metal" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular response to metal ion](http://purl.obolibrary.org/obo/GO_0071248) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular response to metal ion](http://purl.obolibrary.org/obo/GO_0071248) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular response to metal ion](http://purl.obolibrary.org/obo/GO_0071248) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- Class: [cellular response to metal ion](http://purl.obolibrary.org/obo/GO_0071248) + +- [cellular response to metal ion](http://purl.obolibrary.org/obo/GO_0071248) EquivalentTo [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213)) + +- [cellular response to metal ion](http://purl.obolibrary.org/obo/GO_0071248) SubClassOf [cellular response to inorganic substance](http://purl.obolibrary.org/obo/GO_0071241) + +- [cellular response to metal ion](http://purl.obolibrary.org/obo/GO_0071248) SubClassOf [response to metal ion](http://purl.obolibrary.org/obo/GO_0010038) + + + +### cellular response to mineralocorticoid stimulus `http://purl.obolibrary.org/obo/GO_0071389` +#### Removed +- [cellular response to mineralocorticoid stimulus](http://purl.obolibrary.org/obo/GO_0071389) SubClassOf [cellular response to corticosteroid stimulus](http://purl.obolibrary.org/obo/GO_0071384) + +#### Added +- [cellular response to mineralocorticoid stimulus](http://purl.obolibrary.org/obo/GO_0071389) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to monoamine stimulus `http://purl.obolibrary.org/obo/GO_0071868` +#### Removed +- [cellular response to monoamine stimulus](http://purl.obolibrary.org/obo/GO_0071868) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-09-13T02:38:52Z" + +- [cellular response to monoamine stimulus](http://purl.obolibrary.org/obo/GO_0071868) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0071868" + +- [cellular response to monoamine stimulus](http://purl.obolibrary.org/obo/GO_0071868) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- [cellular response to monoamine stimulus](http://purl.obolibrary.org/obo/GO_0071868) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to monoamine stimulus" + +- [cellular response to monoamine stimulus](http://purl.obolibrary.org/obo/GO_0071868) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular response to monoamine stimulus](http://purl.obolibrary.org/obo/GO_0071868) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [cellular response to monoamine stimulus](http://purl.obolibrary.org/obo/GO_0071868) + +- [cellular response to monoamine stimulus](http://purl.obolibrary.org/obo/GO_0071868) EquivalentTo [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534)) + +- [cellular response to monoamine stimulus](http://purl.obolibrary.org/obo/GO_0071868) SubClassOf [cellular response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0071417) + +- [cellular response to monoamine stimulus](http://purl.obolibrary.org/obo/GO_0071868) SubClassOf [response to monoamine](http://purl.obolibrary.org/obo/GO_0071867) + + + +### cellular response to monosaccharide stimulus `http://purl.obolibrary.org/obo/GO_0071326` +#### Removed +- [cellular response to monosaccharide stimulus](http://purl.obolibrary.org/obo/GO_0071326) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- [cellular response to monosaccharide stimulus](http://purl.obolibrary.org/obo/GO_0071326) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2009-12-10T05:27:18Z" + +- [cellular response to monosaccharide stimulus](http://purl.obolibrary.org/obo/GO_0071326) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to monosaccharide stimulus" + +- [cellular response to monosaccharide stimulus](http://purl.obolibrary.org/obo/GO_0071326) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular response to monosaccharide stimulus](http://purl.obolibrary.org/obo/GO_0071326) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0071326" + +- [cellular response to monosaccharide stimulus](http://purl.obolibrary.org/obo/GO_0071326) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- Class: [cellular response to monosaccharide stimulus](http://purl.obolibrary.org/obo/GO_0071326) + +- [cellular response to monosaccharide stimulus](http://purl.obolibrary.org/obo/GO_0071326) EquivalentTo [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381)) + +- [cellular response to monosaccharide stimulus](http://purl.obolibrary.org/obo/GO_0071326) SubClassOf [response to monosaccharide](http://purl.obolibrary.org/obo/GO_0034284) + +- [cellular response to monosaccharide stimulus](http://purl.obolibrary.org/obo/GO_0071326) SubClassOf [cellular response to carbohydrate stimulus](http://purl.obolibrary.org/obo/GO_0071322) + + + +### cellular response to nitric oxide `http://purl.obolibrary.org/obo/GO_0071732` +#### Removed +- [cellular response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071732) SubClassOf [cellular response to reactive nitrogen species](http://purl.obolibrary.org/obo/GO_1902170) + +- [cellular response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071732) SubClassOf [cellular response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901701) + + + +### cellular response to norepinephrine stimulus `http://purl.obolibrary.org/obo/GO_0071874` +#### Removed +- [cellular response to norepinephrine stimulus](http://purl.obolibrary.org/obo/GO_0071874) SubClassOf [cellular response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901699) + +#### Added +- [cellular response to norepinephrine stimulus](http://purl.obolibrary.org/obo/GO_0071874) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to organonitrogen compound `http://purl.obolibrary.org/obo/GO_0071417` +#### Removed +- [cellular response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0071417) SubClassOf [cellular response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901699) + + + +### cellular response to oxidative stress `http://purl.obolibrary.org/obo/GO_0034599` +#### Removed +- [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0034599" + +- [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "adaptive response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:add" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:vk" + +- [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to oxidative stress" + +- Class: [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599) + +- [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599) SubClassOf [cellular response to chemical stress](http://purl.obolibrary.org/obo/GO_0062197) + +- [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599) SubClassOf [response to oxidative stress](http://purl.obolibrary.org/obo/GO_0006979) + + + +### cellular response to oxygen radical `http://purl.obolibrary.org/obo/GO_0071450` +#### Removed +- [cellular response to oxygen radical](http://purl.obolibrary.org/obo/GO_0071450) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0071450" + +- [cellular response to oxygen radical](http://purl.obolibrary.org/obo/GO_0071450) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular response to oxygen radical](http://purl.obolibrary.org/obo/GO_0071450) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2009-12-16T04:38:52Z" + +- [cellular response to oxygen radical](http://purl.obolibrary.org/obo/GO_0071450) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular response to oxygen radical](http://purl.obolibrary.org/obo/GO_0071450) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- [cellular response to oxygen radical](http://purl.obolibrary.org/obo/GO_0071450) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to oxygen radical" + +- Class: [cellular response to oxygen radical](http://purl.obolibrary.org/obo/GO_0071450) + +- [cellular response to oxygen radical](http://purl.obolibrary.org/obo/GO_0071450) EquivalentTo [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [oxygen radical](http://purl.obolibrary.org/obo/CHEBI_61073)) + +- [cellular response to oxygen radical](http://purl.obolibrary.org/obo/GO_0071450) SubClassOf [response to oxygen radical](http://purl.obolibrary.org/obo/GO_0000305) + +- [cellular response to oxygen radical](http://purl.obolibrary.org/obo/GO_0071450) SubClassOf [cellular response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0034614) + + + +### cellular response to peptide `http://purl.obolibrary.org/obo/GO_1901653` +#### Removed +- [cellular response to peptide](http://purl.obolibrary.org/obo/GO_1901653) SubClassOf [cellular response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0071417) + +- [cellular response to peptide](http://purl.obolibrary.org/obo/GO_1901653) SubClassOf [cellular response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901701) + +#### Added +- [cellular response to peptide](http://purl.obolibrary.org/obo/GO_1901653) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to peptide hormone stimulus `http://purl.obolibrary.org/obo/GO_0071375` +#### Removed +- [cellular response to peptide hormone stimulus](http://purl.obolibrary.org/obo/GO_0071375) SubClassOf [cellular response to peptide](http://purl.obolibrary.org/obo/GO_1901653) + +#### Added +- [cellular response to peptide hormone stimulus](http://purl.obolibrary.org/obo/GO_0071375) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to progesterone stimulus `http://purl.obolibrary.org/obo/GO_0071393` +#### Removed +- [cellular response to progesterone stimulus](http://purl.obolibrary.org/obo/GO_0071393) SubClassOf [cellular response to ketone](http://purl.obolibrary.org/obo/GO_1901655) + +- [cellular response to progesterone stimulus](http://purl.obolibrary.org/obo/GO_0071393) SubClassOf [cellular response to steroid hormone stimulus](http://purl.obolibrary.org/obo/GO_0071383) + +#### Added +- [cellular response to progesterone stimulus](http://purl.obolibrary.org/obo/GO_0071393) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to reactive nitrogen species `http://purl.obolibrary.org/obo/GO_1902170` +#### Removed +- [cellular response to reactive nitrogen species](http://purl.obolibrary.org/obo/GO_1902170) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902170" + +- [cellular response to reactive nitrogen species](http://purl.obolibrary.org/obo/GO_1902170) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to reactive nitrogen species" + +- [cellular response to reactive nitrogen species](http://purl.obolibrary.org/obo/GO_1902170) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular response to reactive nitrogen species](http://purl.obolibrary.org/obo/GO_1902170) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:1990106" + +- [cellular response to reactive nitrogen species](http://purl.obolibrary.org/obo/GO_1902170) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2013-05-23T00:23:59Z" + +- [cellular response to reactive nitrogen species](http://purl.obolibrary.org/obo/GO_1902170) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tb" + +- [cellular response to reactive nitrogen species](http://purl.obolibrary.org/obo/GO_1902170) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22504638" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:sl" + +- Class: [cellular response to reactive nitrogen species](http://purl.obolibrary.org/obo/GO_1902170) + +- [cellular response to reactive nitrogen species](http://purl.obolibrary.org/obo/GO_1902170) EquivalentTo [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764)) + +- [cellular response to reactive nitrogen species](http://purl.obolibrary.org/obo/GO_1902170) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764) + +- [cellular response to reactive nitrogen species](http://purl.obolibrary.org/obo/GO_1902170) SubClassOf [cellular response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901699) + + + +### cellular response to reactive oxygen species `http://purl.obolibrary.org/obo/GO_0034614` +#### Removed +- [cellular response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0034614) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular response to reactive oxidative species" + +- [cellular response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0034614) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular response to AOS" + +- [cellular response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0034614) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular response to active oxygen species" + +- [cellular response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0034614) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0034614) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular response to ROS" + +- [cellular response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0034614) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0034614" + +- [cellular response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0034614) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to reactive oxygen species" + +- [cellular response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0034614) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular response to ROI" + +- [cellular response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0034614) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0034614) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular response to reactive oxygen intermediate" + +- Class: [cellular response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0034614) + +- [cellular response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0034614) EquivalentTo [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [reactive oxygen species](http://purl.obolibrary.org/obo/CHEBI_26523)) + +- [cellular response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0034614) SubClassOf [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) + +- [cellular response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0034614) SubClassOf [cellular response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901701) + +- [cellular response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0034614) SubClassOf [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599) + + + +### cellular response to salt `http://purl.obolibrary.org/obo/GO_1902075` +#### Removed +- [cellular response to salt](http://purl.obolibrary.org/obo/GO_1902075) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to salt" + +- [cellular response to salt](http://purl.obolibrary.org/obo/GO_1902075) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902075" + +- [cellular response to salt](http://purl.obolibrary.org/obo/GO_1902075) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2013-04-22T15:42:02Z" + +- [cellular response to salt](http://purl.obolibrary.org/obo/GO_1902075) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "cellular response to salinity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mls" + +- [cellular response to salt](http://purl.obolibrary.org/obo/GO_1902075) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mls" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16666921" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [cellular response to salt](http://purl.obolibrary.org/obo/GO_1902075) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mls" + +- [cellular response to salt](http://purl.obolibrary.org/obo/GO_1902075) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [cellular response to salt](http://purl.obolibrary.org/obo/GO_1902075) + +- [cellular response to salt](http://purl.obolibrary.org/obo/GO_1902075) EquivalentTo [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [salt](http://purl.obolibrary.org/obo/CHEBI_24866)) + +- [cellular response to salt](http://purl.obolibrary.org/obo/GO_1902075) SubClassOf [response to salt](http://purl.obolibrary.org/obo/GO_1902074) + +- [cellular response to salt](http://purl.obolibrary.org/obo/GO_1902075) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + + +### cellular response to serotonin `http://purl.obolibrary.org/obo/GO_1904015` +#### Removed +- [cellular response to serotonin](http://purl.obolibrary.org/obo/GO_1904015) SubClassOf [cellular response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901699) + +#### Added +- [cellular response to serotonin](http://purl.obolibrary.org/obo/GO_1904015) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to steroid hormone stimulus `http://purl.obolibrary.org/obo/GO_0071383` +#### Removed +- [cellular response to steroid hormone stimulus](http://purl.obolibrary.org/obo/GO_0071383) SubClassOf [cellular response to lipid](http://purl.obolibrary.org/obo/GO_0071396) + +- [cellular response to steroid hormone stimulus](http://purl.obolibrary.org/obo/GO_0071383) SubClassOf [cellular response to organic cyclic compound](http://purl.obolibrary.org/obo/GO_0071407) + +#### Added +- [cellular response to steroid hormone stimulus](http://purl.obolibrary.org/obo/GO_0071383) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to stress `http://purl.obolibrary.org/obo/GO_0033554` +#### Removed +- [cellular response to stress](http://purl.obolibrary.org/obo/GO_0033554) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to stress" + +- [cellular response to stress](http://purl.obolibrary.org/obo/GO_0033554) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular response to stress](http://purl.obolibrary.org/obo/GO_0033554) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular response to stress](http://purl.obolibrary.org/obo/GO_0033554) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [gocheck_do_not_manually_annotate](http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate) + +- [cellular response to stress](http://purl.obolibrary.org/obo/GO_0033554) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." + +- [cellular response to stress](http://purl.obolibrary.org/obo/GO_0033554) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0033554" + +- Class: [cellular response to stress](http://purl.obolibrary.org/obo/GO_0033554) + +- [cellular response to stress](http://purl.obolibrary.org/obo/GO_0033554) SubClassOf [cellular response to stimulus](http://purl.obolibrary.org/obo/GO_0051716) + +- [cellular response to stress](http://purl.obolibrary.org/obo/GO_0033554) SubClassOf [response to stress](http://purl.obolibrary.org/obo/GO_0006950) + + + +### cellular response to superoxide `http://purl.obolibrary.org/obo/GO_0071451` +#### Removed +- [cellular response to superoxide](http://purl.obolibrary.org/obo/GO_0071451) SubClassOf [cellular response to oxygen radical](http://purl.obolibrary.org/obo/GO_0071450) + +#### Added +- [cellular response to superoxide](http://purl.obolibrary.org/obo/GO_0071451) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to testosterone stimulus `http://purl.obolibrary.org/obo/GO_0071394` +#### Removed +- [cellular response to testosterone stimulus](http://purl.obolibrary.org/obo/GO_0071394) SubClassOf [cellular response to organic cyclic compound](http://purl.obolibrary.org/obo/GO_0071407) + +- [cellular response to testosterone stimulus](http://purl.obolibrary.org/obo/GO_0071394) SubClassOf [cellular response to lipid](http://purl.obolibrary.org/obo/GO_0071396) + +- [cellular response to testosterone stimulus](http://purl.obolibrary.org/obo/GO_0071394) SubClassOf [cellular response to ketone](http://purl.obolibrary.org/obo/GO_1901655) + +#### Added +- [cellular response to testosterone stimulus](http://purl.obolibrary.org/obo/GO_0071394) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cellular response to vasopressin `http://purl.obolibrary.org/obo/GO_1904117` +#### Removed +- [cellular response to vasopressin](http://purl.obolibrary.org/obo/GO_1904117) SubClassOf [cellular response to peptide hormone stimulus](http://purl.obolibrary.org/obo/GO_0071375) + +#### Added +- [cellular response to vasopressin](http://purl.obolibrary.org/obo/GO_1904117) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + +### cementoblast `http://purl.obolibrary.org/obo/CL_0000061` +#### Removed +- [cementoblast](http://purl.obolibrary.org/obo/CL_0000061) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000859" + + + +### central memory CD4-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000904` +#### Removed +- [central memory CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000904) EquivalentTo [CD4-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001204) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) + +- [central memory CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000904) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + +#### Added +- [central memory CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000904) EquivalentTo [CD4-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001204) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) + +- [central memory CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000904) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + + +### central memory CD8-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000907` +#### Removed +- [central memory CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000907) EquivalentTo [CD8-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001203) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) + +- [central memory CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000907) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + +#### Added +- [central memory CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000907) EquivalentTo [CD8-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001203) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) + +- [central memory CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000907) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + + +### central nervous system depressant `http://purl.obolibrary.org/obo/CHEBI_35488` +#### Removed +- [central nervous system depressant](http://purl.obolibrary.org/obo/CHEBI_35488) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CNS depressants" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [central nervous system depressant](http://purl.obolibrary.org/obo/CHEBI_35488) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A loosely defined group of drugs that tend to reduce the activity of the central nervous system." + +- [central nervous system depressant](http://purl.obolibrary.org/obo/CHEBI_35488) [label](http://www.w3.org/2000/01/rdf-schema#label) "central nervous system depressant" + +- [central nervous system depressant](http://purl.obolibrary.org/obo/CHEBI_35488) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35488" + +- [central nervous system depressant](http://purl.obolibrary.org/obo/CHEBI_35488) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [central nervous system depressant](http://purl.obolibrary.org/obo/CHEBI_35488) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "central nervous system depressants" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [central nervous system depressant](http://purl.obolibrary.org/obo/CHEBI_35488) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [central nervous system depressant](http://purl.obolibrary.org/obo/CHEBI_35488) + +- [central nervous system depressant](http://purl.obolibrary.org/obo/CHEBI_35488) SubClassOf [central nervous system drug](http://purl.obolibrary.org/obo/CHEBI_35470) + + + +### central nervous system drug `http://purl.obolibrary.org/obo/CHEBI_35470` +#### Removed +- [central nervous system drug](http://purl.obolibrary.org/obo/CHEBI_35470) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "central nervous system agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [central nervous system drug](http://purl.obolibrary.org/obo/CHEBI_35470) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [central nervous system drug](http://purl.obolibrary.org/obo/CHEBI_35470) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system." + +- [central nervous system drug](http://purl.obolibrary.org/obo/CHEBI_35470) [label](http://www.w3.org/2000/01/rdf-schema#label) "central nervous system drug" + +- [central nervous system drug](http://purl.obolibrary.org/obo/CHEBI_35470) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CNS drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [central nervous system drug](http://purl.obolibrary.org/obo/CHEBI_35470) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35470" + +- [central nervous system drug](http://purl.obolibrary.org/obo/CHEBI_35470) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CNS agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [central nervous system drug](http://purl.obolibrary.org/obo/CHEBI_35470) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [central nervous system drug](http://purl.obolibrary.org/obo/CHEBI_35470) + +- [central nervous system drug](http://purl.obolibrary.org/obo/CHEBI_35470) SubClassOf [drug](http://purl.obolibrary.org/obo/CHEBI_23888) + + + +### cerebral cortex neuron `http://purl.obolibrary.org/obo/CL_0010012` +#### Removed +- [cerebral cortex neuron](http://purl.obolibrary.org/obo/CL_0010012) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0002609" + + + +### chalcocarbonic acid `http://purl.obolibrary.org/obo/CHEBI_36961` +#### Removed +- [chalcocarbonic acid](http://purl.obolibrary.org/obo/CHEBI_36961) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "chalcocarbonic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [chalcocarbonic acid](http://purl.obolibrary.org/obo/CHEBI_36961) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "chalcocarbonic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcocarbonic acid](http://purl.obolibrary.org/obo/CHEBI_36961) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [chalcocarbonic acid](http://purl.obolibrary.org/obo/CHEBI_36961) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36961" + +- [chalcocarbonic acid](http://purl.obolibrary.org/obo/CHEBI_36961) [label](http://www.w3.org/2000/01/rdf-schema#label) "chalcocarbonic acid" + +- [chalcocarbonic acid](http://purl.obolibrary.org/obo/CHEBI_36961) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chalcocarbonic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcocarbonic acid](http://purl.obolibrary.org/obo/CHEBI_36961) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [chalcocarbonic acid](http://purl.obolibrary.org/obo/CHEBI_36961) + +- [chalcocarbonic acid](http://purl.obolibrary.org/obo/CHEBI_36961) SubClassOf [organochalcogen compound](http://purl.obolibrary.org/obo/CHEBI_36962) + + + +### chalcogen `http://purl.obolibrary.org/obo/CHEBI_33303` +#### Removed +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "chalcogens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "group 16 elements" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "calcogenos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anfigeno" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chalcogene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Chalkogen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Chalkogene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33303" + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [label](http://www.w3.org/2000/01/rdf-schema#label) "chalcogen" + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "chalcogen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any p-block element belonging to the group 16 family of the periodic table." + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17084588" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chalcogenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "group VI elements" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anfigenos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "calcogeno" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) + +- [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) SubClassOf [p-block element atom](http://purl.obolibrary.org/obo/CHEBI_33560) + + + +### chalcogen hydride `http://purl.obolibrary.org/obo/CHEBI_36902` +#### Removed +- [chalcogen hydride](http://purl.obolibrary.org/obo/CHEBI_36902) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [chalcogen hydride](http://purl.obolibrary.org/obo/CHEBI_36902) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36902" + +- [chalcogen hydride](http://purl.obolibrary.org/obo/CHEBI_36902) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "chalcogen hydride" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcogen hydride](http://purl.obolibrary.org/obo/CHEBI_36902) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chalcogen hydrides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcogen hydride](http://purl.obolibrary.org/obo/CHEBI_36902) [label](http://www.w3.org/2000/01/rdf-schema#label) "chalcogen hydride" + +- [chalcogen hydride](http://purl.obolibrary.org/obo/CHEBI_36902) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [chalcogen hydride](http://purl.obolibrary.org/obo/CHEBI_36902) + +- [chalcogen hydride](http://purl.obolibrary.org/obo/CHEBI_36902) SubClassOf [inorganic hydride](http://purl.obolibrary.org/obo/CHEBI_33242) + +- [chalcogen hydride](http://purl.obolibrary.org/obo/CHEBI_36902) SubClassOf [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) + + + +### chalcogen molecular entity `http://purl.obolibrary.org/obo/CHEBI_33304` +#### Removed +- [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chalcogen compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any p-block molecular entity containing a chalcogen." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chalcogen compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chalcogen molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) [label](http://www.w3.org/2000/01/rdf-schema#label) "chalcogen molecular entity" + +- [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33304" + +- [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "chalcogen molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chalcogen molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "chalcogen molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) + +- [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) + +- [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) SubClassOf [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) + + + +### chalcogen oxoacid `http://purl.obolibrary.org/obo/CHEBI_33484` +#### Removed +- [chalcogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33484) [label](http://www.w3.org/2000/01/rdf-schema#label) "chalcogen oxoacid" + +- [chalcogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33484) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "chalcogen oxoacid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33484) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33484" + +- [chalcogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33484) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [chalcogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33484) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chalcogen oxoacids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33484) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [chalcogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33484) + +- [chalcogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33484) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [inorganic acid](http://purl.obolibrary.org/obo/CHEBI_138103) + +- [chalcogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33484) SubClassOf [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) + + + +### chalcogen oxoanion `http://purl.obolibrary.org/obo/CHEBI_33485` +#### Removed +- [chalcogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33485) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [chalcogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33485) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [chalcogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33485) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33485" + +- [chalcogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33485) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "chalcogen oxoanion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33485) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chalcogen oxoanions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chalcogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33485) [label](http://www.w3.org/2000/01/rdf-schema#label) "chalcogen oxoanion" + +- Class: [chalcogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33485) + +- [chalcogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33485) SubClassOf [oxoanion](http://purl.obolibrary.org/obo/CHEBI_35406) + + + +### characteristic of part of `http://purl.obolibrary.org/obo/RO_0002314` +#### Removed +- [characteristic of part of](http://purl.obolibrary.org/obo/RO_0002314) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [characteristic of part of](http://purl.obolibrary.org/obo/RO_0002314) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### charge `http://purl.obolibrary.org/obo/chebi/charge` +#### Removed +- AnnotationProperty: [charge](http://purl.obolibrary.org/obo/chebi/charge) + + + +### chemical entity `http://purl.obolibrary.org/obo/CHEBI_24431` +#### Removed +- [chemical entity](http://purl.obolibrary.org/obo/CHEBI_24431) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [chemical entity](http://purl.obolibrary.org/obo/CHEBI_24431) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "chemical entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [chemical entity](http://purl.obolibrary.org/obo/CHEBI_24431) [label](http://www.w3.org/2000/01/rdf-schema#label) "chemical entity" + + + +### chemical role `http://purl.obolibrary.org/obo/CHEBI_51086` +#### Removed +- [chemical role](http://purl.obolibrary.org/obo/CHEBI_51086) [label](http://www.w3.org/2000/01/rdf-schema#label) "chemical role" + +- [chemical role](http://purl.obolibrary.org/obo/CHEBI_51086) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [chemical role](http://purl.obolibrary.org/obo/CHEBI_51086) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [chemical role](http://purl.obolibrary.org/obo/CHEBI_51086) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A role played by the molecular entity or part thereof within a chemical context." + +- [chemical role](http://purl.obolibrary.org/obo/CHEBI_51086) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:51086" + +- Class: [chemical role](http://purl.obolibrary.org/obo/CHEBI_51086) + +- [chemical role](http://purl.obolibrary.org/obo/CHEBI_51086) SubClassOf [role](http://purl.obolibrary.org/obo/CHEBI_50906) + +- [chemical role](http://purl.obolibrary.org/obo/CHEBI_51086) SubClassOf [role](http://purl.obolibrary.org/obo/BFO_0000023) + + + +### chemical substance `http://purl.obolibrary.org/obo/CHEBI_59999` +#### Removed +- [chemical substance](http://purl.obolibrary.org/obo/CHEBI_59999) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:59999" + +- [chemical substance](http://purl.obolibrary.org/obo/CHEBI_59999) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [chemical substance](http://purl.obolibrary.org/obo/CHEBI_59999) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [chemical substance](http://purl.obolibrary.org/obo/CHEBI_59999) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Chemische Substanz" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chemical substance](http://purl.obolibrary.org/obo/CHEBI_59999) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types." + +- [chemical substance](http://purl.obolibrary.org/obo/CHEBI_59999) [label](http://www.w3.org/2000/01/rdf-schema#label) "chemical substance" + +- Class: [chemical substance](http://purl.obolibrary.org/obo/CHEBI_59999) + +- [chemical substance](http://purl.obolibrary.org/obo/CHEBI_59999) SubClassOf [chemical entity](http://purl.obolibrary.org/obo/CHEBI_24431) + + + +### cholane `http://purl.obolibrary.org/obo/CHEBI_35519` +#### Removed +- [cholane](http://purl.obolibrary.org/obo/CHEBI_35519) [label](http://www.w3.org/2000/01/rdf-schema#label) "cholane" + +- [cholane](http://purl.obolibrary.org/obo/CHEBI_35519) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35519" + +- [cholane](http://purl.obolibrary.org/obo/CHEBI_35519) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C24H42/c1-5-8-17(2)20-12-13-21-19-11-10-18-9-6-7-15-23(18,3)22(19)14-16-24(20,21)4/h17-22H,5-16H2,1-4H3/t17-,18?,19+,20-,21+,22+,23+,24-/m1/s1" + +- [cholane](http://purl.obolibrary.org/obo/CHEBI_35519) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [cholane](http://purl.obolibrary.org/obo/CHEBI_35519) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [cholane](http://purl.obolibrary.org/obo/CHEBI_35519) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4CCCC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC" + +- [cholane](http://purl.obolibrary.org/obo/CHEBI_35519) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C24H42" + +- [cholane](http://purl.obolibrary.org/obo/CHEBI_35519) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "QSHQKIURKJITMZ-BRPMRXRMSA-N" + +- [cholane](http://purl.obolibrary.org/obo/CHEBI_35519) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cholane" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [cholane](http://purl.obolibrary.org/obo/CHEBI_35519) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "330.32865" + +- [cholane](http://purl.obolibrary.org/obo/CHEBI_35519) [mass](http://purl.obolibrary.org/obo/chebi/mass) "330.59028" + +- [cholane](http://purl.obolibrary.org/obo/CHEBI_35519) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [cholane](http://purl.obolibrary.org/obo/CHEBI_35519) + +- [cholane](http://purl.obolibrary.org/obo/CHEBI_35519) SubClassOf [steroid fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35508) + + + +### cholangiocyte `http://purl.obolibrary.org/obo/CL_1000488` +#### Removed +- [cholangiocyte](http://purl.obolibrary.org/obo/CL_1000488) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### cholanic acid `http://purl.obolibrary.org/obo/CHEBI_36237` +#### Removed +- [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17?,18+,19-,20+,21+,23+,24-/m1/s1" + +- [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "360.30283" + +- [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:25312-65-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "RPKLZQLYODPWTM-KBMWBBLPSA-N" + +- [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24." + +- [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) [label](http://www.w3.org/2000/01/rdf-schema#label) "cholanic acid" + +- [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:13246008" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) [mass](http://purl.obolibrary.org/obo/chebi/mass) "360.57320" + +- [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cholan-24-oic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Patent:JP2008069152" + +- [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C24H40O2" + +- [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4CCCC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(O)=O" + +- [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36237" + +- Class: [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) + +- [cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36237) SubClassOf [cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36278) + + + +### cholanic acids `http://purl.obolibrary.org/obo/CHEBI_36278` +#### Removed +- [cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36278) [label](http://www.w3.org/2000/01/rdf-schema#label) "cholanic acids" + +- [cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36278) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#1_STAR) + +- [cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36278) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23166" + +- [cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36278) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36278" + +- [cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36278) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36278) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23211" + +- Class: [cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36278) + +- [cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36278) SubClassOf [cholanoid](http://purl.obolibrary.org/obo/CHEBI_36078) + +- [cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36278) SubClassOf [steroid acid](http://purl.obolibrary.org/obo/CHEBI_47891) + + + +### cholanoid `http://purl.obolibrary.org/obo/CHEBI_36078` +#### Removed +- [cholanoid](http://purl.obolibrary.org/obo/CHEBI_36078) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [cholanoid](http://purl.obolibrary.org/obo/CHEBI_36078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LIPID_MAPS_class:LMST04" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "LIPID MAPS" + +- [cholanoid](http://purl.obolibrary.org/obo/CHEBI_36078) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:50419" + +- [cholanoid](http://purl.obolibrary.org/obo/CHEBI_36078) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bile acids and derivatives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LIPID_MAPS" + +- [cholanoid](http://purl.obolibrary.org/obo/CHEBI_36078) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cholanoids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cholanoid](http://purl.obolibrary.org/obo/CHEBI_36078) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36078" + +- [cholanoid](http://purl.obolibrary.org/obo/CHEBI_36078) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22867" + +- [cholanoid](http://purl.obolibrary.org/obo/CHEBI_36078) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [cholanoid](http://purl.obolibrary.org/obo/CHEBI_36078) [label](http://www.w3.org/2000/01/rdf-schema#label) "cholanoid" + +- Class: [cholanoid](http://purl.obolibrary.org/obo/CHEBI_36078) + +- [cholanoid](http://purl.obolibrary.org/obo/CHEBI_36078) SubClassOf [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) + +- [cholanoid](http://purl.obolibrary.org/obo/CHEBI_36078) SubClassOf [has_parent_hydride](http://purl.obolibrary.org/obo/chebi#has_parent_hydride) some [cholane](http://purl.obolibrary.org/obo/CHEBI_35519) + + + +### cholinergic agonist `http://purl.obolibrary.org/obo/CHEBI_38324` +#### Removed +- [cholinergic agonist](http://purl.obolibrary.org/obo/CHEBI_38324) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [cholinergic agonist](http://purl.obolibrary.org/obo/CHEBI_38324) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acetylcholine agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cholinergic agonist](http://purl.obolibrary.org/obo/CHEBI_38324) [label](http://www.w3.org/2000/01/rdf-schema#label) "cholinergic agonist" + +- [cholinergic agonist](http://purl.obolibrary.org/obo/CHEBI_38324) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:38324" + +- [cholinergic agonist](http://purl.obolibrary.org/obo/CHEBI_38324) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acetylcholine agonist" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cholinergic agonist](http://purl.obolibrary.org/obo/CHEBI_38324) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acetylcholine receptor agonist" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPHAR" + +- [cholinergic agonist](http://purl.obolibrary.org/obo/CHEBI_38324) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cholinergic agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cholinergic agonist](http://purl.obolibrary.org/obo/CHEBI_38324) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any drug that binds to and activates cholinergic receptors." + +- [cholinergic agonist](http://purl.obolibrary.org/obo/CHEBI_38324) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cholinomimetic" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cholinergic agonist](http://purl.obolibrary.org/obo/CHEBI_38324) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [cholinergic agonist](http://purl.obolibrary.org/obo/CHEBI_38324) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cholinomimetics" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [cholinergic agonist](http://purl.obolibrary.org/obo/CHEBI_38324) + +- [cholinergic agonist](http://purl.obolibrary.org/obo/CHEBI_38324) SubClassOf [cholinergic drug](http://purl.obolibrary.org/obo/CHEBI_38323) + + + +### cholinergic drug `http://purl.obolibrary.org/obo/CHEBI_38323` +#### Removed +- [cholinergic drug](http://purl.obolibrary.org/obo/CHEBI_38323) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cholinomimetic" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cholinergic drug](http://purl.obolibrary.org/obo/CHEBI_38323) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cholinergic agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cholinergic drug](http://purl.obolibrary.org/obo/CHEBI_38323) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [cholinergic drug](http://purl.obolibrary.org/obo/CHEBI_38323) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [cholinergic drug](http://purl.obolibrary.org/obo/CHEBI_38323) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:38323" + +- [cholinergic drug](http://purl.obolibrary.org/obo/CHEBI_38323) [label](http://www.w3.org/2000/01/rdf-schema#label) "cholinergic drug" + +- [cholinergic drug](http://purl.obolibrary.org/obo/CHEBI_38323) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cholinergic drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cholinergic drug](http://purl.obolibrary.org/obo/CHEBI_38323) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons." + +- Class: [cholinergic drug](http://purl.obolibrary.org/obo/CHEBI_38323) + +- [cholinergic drug](http://purl.obolibrary.org/obo/CHEBI_38323) SubClassOf [neurotransmitter agent](http://purl.obolibrary.org/obo/CHEBI_35942) + + + +### chondroitin D-glucuronate `http://purl.obolibrary.org/obo/CHEBI_16137` +#### Removed +- [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A mucopolysaccharide composed of repeating beta-D-glucopyranuronosyl-(1->3)-beta-D-N-acetylgalactosaminyl units." + +- [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:16137" + +- [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13989" + +- [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Chondroitin-D-glucuronate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) [formula](http://purl.obolibrary.org/obo/chebi/formula) "(C14H21NO11)nH2O" + +- [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23221" + +- [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) [label](http://www.w3.org/2000/01/rdf-schema#label) "chondroitin D-glucuronate" + +- [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:G11334" + +- [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:3673" + +- [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Chondroitin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13992" + +- [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00401" + +- Class: [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) + +- [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [chondroitin D-glucuronate anion](http://purl.obolibrary.org/obo/CHEBI_57652) + +- [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) SubClassOf [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) + + + +### chondroitin D-glucuronate anion `http://purl.obolibrary.org/obo/CHEBI_57652` +#### Removed +- [chondroitin D-glucuronate anion](http://purl.obolibrary.org/obo/CHEBI_57652) [formula](http://purl.obolibrary.org/obo/chebi/formula) "H2O(C14H20NO11)n" + +- [chondroitin D-glucuronate anion](http://purl.obolibrary.org/obo/CHEBI_57652) [label](http://www.w3.org/2000/01/rdf-schema#label) "chondroitin D-glucuronate anion" + +- [chondroitin D-glucuronate anion](http://purl.obolibrary.org/obo/CHEBI_57652) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:57652" + +- [chondroitin D-glucuronate anion](http://purl.obolibrary.org/obo/CHEBI_57652) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [chondroitin D-glucuronate anion](http://purl.obolibrary.org/obo/CHEBI_57652) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chondroitin D-glucuronate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [chondroitin D-glucuronate anion](http://purl.obolibrary.org/obo/CHEBI_57652) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chondroitin D-glucuronate polyanion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chondroitin D-glucuronate anion](http://purl.obolibrary.org/obo/CHEBI_57652) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [chondroitin D-glucuronate anion](http://purl.obolibrary.org/obo/CHEBI_57652) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Anionic form of chondroitin D-glucuronate arising from deprotonation of the carboxylic acid groups of the repeating units; major species at pH 7.3." + +- Class: [chondroitin D-glucuronate anion](http://purl.obolibrary.org/obo/CHEBI_57652) + +- [chondroitin D-glucuronate anion](http://purl.obolibrary.org/obo/CHEBI_57652) SubClassOf [polyanionic polymer](http://purl.obolibrary.org/obo/CHEBI_61469) + +- [chondroitin D-glucuronate anion](http://purl.obolibrary.org/obo/CHEBI_57652) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) + + + +### chondroitin sulfate `http://purl.obolibrary.org/obo/CHEBI_37397` +#### Removed +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:7538297" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chondroitin polysulfate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23224" + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Chondroitin sulfate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chondroitin sulfates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:3676" + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chondroitin sulfuric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chondroitin sulphate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Chondroitinsulfat" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any of a class of 10--60 kDa glycosaminoglycan sulfates, widely distributed in cartilage and other mammalian connective tissues." + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [label](http://www.w3.org/2000/01/rdf-schema#label) "chondroitin sulfate" + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:37397" + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11514091" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:9007-28-7" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:9007-28-7" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00607" + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [chondroitin D-glucuronate](http://purl.obolibrary.org/obo/CHEBI_16137) + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) SubClassOf [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) + +- [chondroitin sulfate](http://purl.obolibrary.org/obo/CHEBI_37397) SubClassOf [sulfated glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_35722) + + + +### chondroitin sulfate binding `http://purl.obolibrary.org/obo/GO_0035374` +#### Removed +- [chondroitin sulfate binding](http://purl.obolibrary.org/obo/GO_0035374) SubClassOf [sulfur compound binding](http://purl.obolibrary.org/obo/GO_1901681) + +- [chondroitin sulfate binding](http://purl.obolibrary.org/obo/GO_0035374) SubClassOf [glycosaminoglycan binding](http://purl.obolibrary.org/obo/GO_0005539) + +#### Added +- [chondroitin sulfate binding](http://purl.obolibrary.org/obo/GO_0035374) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### chondroitin sulfate biosynthetic process `http://purl.obolibrary.org/obo/GO_0030206` +#### Removed +- [chondroitin sulfate biosynthetic process](http://purl.obolibrary.org/obo/GO_0030206) SubClassOf [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) + +- [chondroitin sulfate biosynthetic process](http://purl.obolibrary.org/obo/GO_0030206) SubClassOf [glycosaminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006024) + +#### Added +- [chondroitin sulfate biosynthetic process](http://purl.obolibrary.org/obo/GO_0030206) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### chondroitin sulfate catabolic process `http://purl.obolibrary.org/obo/GO_0030207` +#### Removed +- [chondroitin sulfate catabolic process](http://purl.obolibrary.org/obo/GO_0030207) SubClassOf [glycosaminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006027) + +- [chondroitin sulfate catabolic process](http://purl.obolibrary.org/obo/GO_0030207) SubClassOf [sulfur compound catabolic process](http://purl.obolibrary.org/obo/GO_0044273) + +#### Added +- [chondroitin sulfate catabolic process](http://purl.obolibrary.org/obo/GO_0030207) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### chondroitin sulfate metabolic process `http://purl.obolibrary.org/obo/GO_0030204` +#### Removed +- [chondroitin sulfate metabolic process](http://purl.obolibrary.org/obo/GO_0030204) SubClassOf [mucopolysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903510) + +- [chondroitin sulfate metabolic process](http://purl.obolibrary.org/obo/GO_0030204) SubClassOf [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) + +#### Added +- [chondroitin sulfate metabolic process](http://purl.obolibrary.org/obo/GO_0030204) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### choroid plexus cell `http://purl.obolibrary.org/obo/CL_4023073` +#### Removed +- [choroid plexus cell](http://purl.obolibrary.org/obo/CL_4023073) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### choroid plexus epithelial cell `http://purl.obolibrary.org/obo/CL_0000706` +#### Removed +- [choroid plexus epithelial cell](http://purl.obolibrary.org/obo/CL_0000706) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000430" + + + +### ciliated cell `http://purl.obolibrary.org/obo/CL_0000064` + +#### Added +- [ciliated cell](http://purl.obolibrary.org/obo/CL_0000064) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + + +### ciliated olfactory receptor neuron `http://purl.obolibrary.org/obo/CL_0000847` +#### Removed +- [ciliated olfactory receptor neuron](http://purl.obolibrary.org/obo/CL_0000847) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + + + +### circulating cell `http://purl.obolibrary.org/obo/CL_0000080` +#### Removed +- [circulating cell](http://purl.obolibrary.org/obo/CL_0000080) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### class switched memory B cell `http://purl.obolibrary.org/obo/CL_0000972` +#### Removed +- [class switched memory B cell](http://purl.obolibrary.org/obo/CL_0000972) EquivalentTo [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [isotype switching](http://purl.obolibrary.org/obo/GO_0045190)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) + +- [class switched memory B cell](http://purl.obolibrary.org/obo/CL_0000972) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753) + +#### Added +- [class switched memory B cell](http://purl.obolibrary.org/obo/CL_0000972) EquivalentTo [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [isotype switching](http://purl.obolibrary.org/obo/GO_0045190)) + +- [class switched memory B cell](http://purl.obolibrary.org/obo/CL_0000972) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753) + + +### classical monocyte `http://purl.obolibrary.org/obo/CL_0000860` +#### Removed +- [classical monocyte](http://purl.obolibrary.org/obo/CL_0000860) EquivalentTo [monocyte](http://purl.obolibrary.org/obo/CL_0000576) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [monocyte chemotaxis](http://purl.obolibrary.org/obo/GO_0002548)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [phagocytosis](http://purl.obolibrary.org/obo/GO_0006909)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [inflammatory response](http://purl.obolibrary.org/obo/GO_0006954)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [C-C chemokine receptor type 2](http://purl.obolibrary.org/obo/PR_000001199)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) + +- [classical monocyte](http://purl.obolibrary.org/obo/CL_0000860) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [classical monocyte](http://purl.obolibrary.org/obo/CL_0000860) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [classical monocyte](http://purl.obolibrary.org/obo/CL_0000860) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +#### Added +- [classical monocyte](http://purl.obolibrary.org/obo/CL_0000860) EquivalentTo [monocyte](http://purl.obolibrary.org/obo/CL_0000576) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [monocyte chemotaxis](http://purl.obolibrary.org/obo/GO_0002548)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [phagocytosis](http://purl.obolibrary.org/obo/GO_0006909)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [inflammatory response](http://purl.obolibrary.org/obo/GO_0006954)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [C-C chemokine receptor type 2](http://purl.obolibrary.org/obo/PR_000001199)) + +- [classical monocyte](http://purl.obolibrary.org/obo/CL_0000860) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [classical monocyte](http://purl.obolibrary.org/obo/CL_0000860) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [classical monocyte](http://purl.obolibrary.org/obo/CL_0000860) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + + +### clathrate compound `http://purl.obolibrary.org/obo/CHEBI_39024` +#### Removed +- [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cage compound" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "clathrates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:39024" + +- [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "clathrate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Inclusion compound in which the guest molecule is in a cage formed by the host molecule or by a lattice of host molecules." + +- [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) [label](http://www.w3.org/2000/01/rdf-schema#label) "clathrate compound" + +- [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "clatratos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "clathrate compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "compuesto de clatrato" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Klathrat" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Clathrat" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Clathratverbindung" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Klathratverbindung" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "clatrato" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- Class: [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) + +- [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) SubClassOf [inclusion compound](http://purl.obolibrary.org/obo/CHEBI_39022) + + + +### cofactor `http://purl.obolibrary.org/obo/CHEBI_23357` +#### Removed +- [cofactor](http://purl.obolibrary.org/obo/CHEBI_23357) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:23357" + +- [cofactor](http://purl.obolibrary.org/obo/CHEBI_23357) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cofactors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [cofactor](http://purl.obolibrary.org/obo/CHEBI_23357) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group)." + +- [cofactor](http://purl.obolibrary.org/obo/CHEBI_23357) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [cofactor](http://purl.obolibrary.org/obo/CHEBI_23357) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cofactor_(biochemistry)" + +- [cofactor](http://purl.obolibrary.org/obo/CHEBI_23357) [label](http://www.w3.org/2000/01/rdf-schema#label) "cofactor" + +- [cofactor](http://purl.obolibrary.org/obo/CHEBI_23357) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cofactor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [cofactor](http://purl.obolibrary.org/obo/CHEBI_23357) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [cofactor](http://purl.obolibrary.org/obo/CHEBI_23357) + +- [cofactor](http://purl.obolibrary.org/obo/CHEBI_23357) SubClassOf [biochemical role](http://purl.obolibrary.org/obo/CHEBI_52206) + + + +### common dendritic progenitor `http://purl.obolibrary.org/obo/CL_0001029` +#### Removed +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) EquivalentTo [hematopoietic lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0002031) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrophage colony-stimulating factor 1 receptor](http://purl.obolibrary.org/obo/PR_000002062)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +#### Added +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) EquivalentTo [hematopoietic lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0002031) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrophage colony-stimulating factor 1 receptor](http://purl.obolibrary.org/obo/PR_000002062)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + + +### common lymphoid progenitor `http://purl.obolibrary.org/obo/CL_0000051` +#### Removed +- [common lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0000051) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000044" + + + +### composed primarily of `http://purl.obolibrary.org/obo/RO_0002473` +#### Removed +- [composed primarily of](http://purl.obolibrary.org/obo/RO_0002473) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [composed primarily of](http://purl.obolibrary.org/obo/RO_0002473) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### composite particle `http://purl.obolibrary.org/obo/CHEBI_36343` +#### Removed +- [composite particle](http://purl.obolibrary.org/obo/CHEBI_36343) [label](http://www.w3.org/2000/01/rdf-schema#label) "composite particle" + +- [composite particle](http://purl.obolibrary.org/obo/CHEBI_36343) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [composite particle](http://purl.obolibrary.org/obo/CHEBI_36343) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [composite particle](http://purl.obolibrary.org/obo/CHEBI_36343) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "composite particles" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [composite particle](http://purl.obolibrary.org/obo/CHEBI_36343) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A subatomic particle known to have substructure (i.e. consisting of smaller particles)." + +- [composite particle](http://purl.obolibrary.org/obo/CHEBI_36343) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36343" + +- Class: [composite particle](http://purl.obolibrary.org/obo/CHEBI_36343) + +- [composite particle](http://purl.obolibrary.org/obo/CHEBI_36343) SubClassOf [subatomic particle](http://purl.obolibrary.org/obo/CHEBI_36342) + + + +### compound eye cone cell `http://purl.obolibrary.org/obo/CL_0000718` +#### Removed +- [compound eye cone cell](http://purl.obolibrary.org/obo/CL_0000718) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### compound eye retinal cell `http://purl.obolibrary.org/obo/CL_0009001` +#### Removed +- [compound eye retinal cell](http://purl.obolibrary.org/obo/CL_0009001) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### conjugated protein `http://purl.obolibrary.org/obo/CHEBI_33837` +#### Removed +- [conjugated protein](http://purl.obolibrary.org/obo/CHEBI_33837) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Conjugated protein is a protein that contains a non-peptide component, usually in stoichiometric proportion." + +- [conjugated protein](http://purl.obolibrary.org/obo/CHEBI_33837) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33837" + +- [conjugated protein](http://purl.obolibrary.org/obo/CHEBI_33837) [label](http://www.w3.org/2000/01/rdf-schema#label) "conjugated protein" + +- [conjugated protein](http://purl.obolibrary.org/obo/CHEBI_33837) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [conjugated protein](http://purl.obolibrary.org/obo/CHEBI_33837) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [conjugated protein](http://purl.obolibrary.org/obo/CHEBI_33837) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "complex protein" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "COMe" + +- [conjugated protein](http://purl.obolibrary.org/obo/CHEBI_33837) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "COMe:PRX000001" + +- [conjugated protein](http://purl.obolibrary.org/obo/CHEBI_33837) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "conjugated proteins" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- Class: [conjugated protein](http://purl.obolibrary.org/obo/CHEBI_33837) + +- [conjugated protein](http://purl.obolibrary.org/obo/CHEBI_33837) SubClassOf [protein](http://purl.obolibrary.org/obo/CHEBI_36080) + +- [conjugated protein](http://purl.obolibrary.org/obo/CHEBI_33837) SubClassOf [protein](http://purl.obolibrary.org/obo/PR_000000001) + + + +### connective tissue cell `http://purl.obolibrary.org/obo/CL_0002320` +#### Removed +- [connective tissue cell](http://purl.obolibrary.org/obo/CL_0002320) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000406" + +- [connective tissue cell](http://purl.obolibrary.org/obo/CL_0002320) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### continuous with `http://purl.obolibrary.org/obo/RO_0002150` +#### Removed +- [continuous with](http://purl.obolibrary.org/obo/RO_0002150) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland" + +#### Added +- [continuous with](http://purl.obolibrary.org/obo/RO_0002150) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + + +### contraceptive drug `http://purl.obolibrary.org/obo/CHEBI_49323` +#### Removed +- [contraceptive drug](http://purl.obolibrary.org/obo/CHEBI_49323) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [contraceptive drug](http://purl.obolibrary.org/obo/CHEBI_49323) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:49323" + +- [contraceptive drug](http://purl.obolibrary.org/obo/CHEBI_49323) [label](http://www.w3.org/2000/01/rdf-schema#label) "contraceptive drug" + +- [contraceptive drug](http://purl.obolibrary.org/obo/CHEBI_49323) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "contraceptive agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [contraceptive drug](http://purl.obolibrary.org/obo/CHEBI_49323) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A chemical substance that prevents or reduces the probability of conception." + +- [contraceptive drug](http://purl.obolibrary.org/obo/CHEBI_49323) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [contraceptive drug](http://purl.obolibrary.org/obo/CHEBI_49323) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "contraceptive drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [contraceptive drug](http://purl.obolibrary.org/obo/CHEBI_49323) + +- [contraceptive drug](http://purl.obolibrary.org/obo/CHEBI_49323) SubClassOf [reproductive control drug](http://purl.obolibrary.org/obo/CHEBI_50689) + + + +### contributes to morphology of `http://purl.obolibrary.org/obo/RO_0002433` +#### Removed +- [contributes to morphology of](http://purl.obolibrary.org/obo/RO_0002433) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [contributes to morphology of](http://purl.obolibrary.org/obo/RO_0002433) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### corneal endothelial cell `http://purl.obolibrary.org/obo/CL_0000132` +#### Removed +- [corneal endothelial cell](http://purl.obolibrary.org/obo/CL_0000132) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Cell of the single layer of large flattened cells covering the surface of the cornea." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tfm" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:A09.371.060.067.31" + +- [corneal endothelial cell](http://purl.obolibrary.org/obo/CL_0000132) SubClassOf [squamous epithelial cell](http://purl.obolibrary.org/obo/CL_0000076) + +#### Added +- [corneal endothelial cell](http://purl.obolibrary.org/obo/CL_0000132) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An hexagonal, flattened, mitochondria-rich endothelial cell that forms a monolayer on the posterior surface of the cornea (the corneal endothelium). Corneal endothelial cells are derived from the neural crest and are responsible for keeping the cornea transparent by maintaining the tissue in a semi-dry state through the action of their ionic pumps and tight junction barrier." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tfm" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:36769303" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:A09.371.060.067.31" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:34741068" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23284695" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21976958" + +- [corneal endothelial cell](http://purl.obolibrary.org/obo/CL_0000132) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [corneal endothelium](http://purl.obolibrary.org/obo/UBERON_0001985) + +- [corneal endothelial cell](http://purl.obolibrary.org/obo/CL_0000132) SubClassOf [endothelial cell](http://purl.obolibrary.org/obo/CL_0000115) + + +### corneal epithelial cell `http://purl.obolibrary.org/obo/CL_0000575` +#### Removed +- [corneal epithelial cell](http://purl.obolibrary.org/obo/CL_0000575) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000431" + + + +### cortical visual area `http://purl.obolibrary.org/obo/UBERON_8440011` +#### Removed +- [cortical visual area](http://purl.obolibrary.org/obo/UBERON_8440011) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-7258-9596](http://orcid.org/0000-0001-7258-9596) + +#### Added +- [cortical visual area](http://purl.obolibrary.org/obo/UBERON_8440011) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-7258-9596](https://orcid.org/0000-0001-7258-9596) + + +### corticosteroid `http://purl.obolibrary.org/obo/CHEBI_50858` +#### Removed +- [corticosteroid](http://purl.obolibrary.org/obo/CHEBI_50858) [label](http://www.w3.org/2000/01/rdf-schema#label) "corticosteroid" + +- [corticosteroid](http://purl.obolibrary.org/obo/CHEBI_50858) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50858" + +- [corticosteroid](http://purl.obolibrary.org/obo/CHEBI_50858) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A natural or synthetic analogue of the hormones secreted by the adrenal gland." + +- [corticosteroid](http://purl.obolibrary.org/obo/CHEBI_50858) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [corticosteroid](http://purl.obolibrary.org/obo/CHEBI_50858) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [corticosteroid](http://purl.obolibrary.org/obo/CHEBI_50858) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corticoides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [corticosteroid](http://purl.obolibrary.org/obo/CHEBI_50858) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corticosteroides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [corticosteroid](http://purl.obolibrary.org/obo/CHEBI_50858) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corticosteroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [corticosteroid](http://purl.obolibrary.org/obo/CHEBI_50858) + +- [corticosteroid](http://purl.obolibrary.org/obo/CHEBI_50858) SubClassOf [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) + + + +### corticosteroid hormone `http://purl.obolibrary.org/obo/CHEBI_36699` +#### Removed +- [corticosteroid hormone](http://purl.obolibrary.org/obo/CHEBI_36699) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any of a class of steroid hormones that are produced in the adrenal cortex." + +- [corticosteroid hormone](http://purl.obolibrary.org/obo/CHEBI_36699) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36699" + +- [corticosteroid hormone](http://purl.obolibrary.org/obo/CHEBI_36699) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corticosteroid hormones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [corticosteroid hormone](http://purl.obolibrary.org/obo/CHEBI_36699) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "adrenal cortex hormones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [corticosteroid hormone](http://purl.obolibrary.org/obo/CHEBI_36699) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [corticosteroid hormone](http://purl.obolibrary.org/obo/CHEBI_36699) [label](http://www.w3.org/2000/01/rdf-schema#label) "corticosteroid hormone" + +- [corticosteroid hormone](http://purl.obolibrary.org/obo/CHEBI_36699) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [corticosteroid hormone](http://purl.obolibrary.org/obo/CHEBI_36699) SubClassOf [corticosteroid](http://purl.obolibrary.org/obo/CHEBI_50858) + +- [corticosteroid hormone](http://purl.obolibrary.org/obo/CHEBI_36699) SubClassOf [steroid hormone](http://purl.obolibrary.org/obo/CHEBI_26764) + + + +### corticotropin `http://purl.obolibrary.org/obo/CHEBI_3892` +#### Removed +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D00146" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:4931" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [label](http://www.w3.org/2000/01/rdf-schema#label) "corticotropin" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corticotropin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [mass](http://purl.obolibrary.org/obo/chebi/mass) "4541.06600" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "SYSMEHFRWGKPVGKKRRPVKVYPDGAEDQLAEAFPLEF" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:9002-60-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:9002-60-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corticotrophinum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A polypeptide hormone produced and secreted by the pituitary gland comprising 39 amino acid residues coupled in a linear sequence. The N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Corticotropin stimulates the cortex of the adrenal gland and boosts the synthesis of corticosteroids, mainly glucocorticoids but also sex steroids (androgens). It is used in the treatment of certain neurological disorders such as infantile spasms and multiple sclerosis, and diagnostically to investigate adrenocortical insufficiency." + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C207H308N56O58S" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cortrophin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:3892" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C207H308N56O58S/c1-108(2)89-140(186(302)240-135(69-74-163(279)280)182(298)254-149(204(320)321)94-117-43-20-15-21-44-117)250-193(309)152-54-35-86-262(152)202(318)147(92-116-41-18-14-19-42-116)252-171(287)114(11)230-175(291)132(66-71-160(273)274)234-170(286)113(10)231-191(307)150(105-265)255-183(299)136(70-75-164(281)282)241-190(306)146(98-165(283)284)249-180(296)133(67-72-161(275)276)235-169(285)112(9)229-157(270)101-225-174(290)145(97-156(213)269)251-194(310)153-55-36-87-263(153)203(319)148(93-119-60-64-123(268)65-61-119)253-199(315)167(110(5)6)257-185(301)129(49-26-30-79-210)243-198(314)168(111(7)8)259-196(312)155-57-38-85-261(155)201(317)139(53-34-83-223-207(218)219)244-178(294)130(51-32-81-221-205(214)215)237-177(293)128(48-25-29-78-209)236-176(292)127(47-24-28-77-208)232-158(271)103-227-197(313)166(109(3)4)258-195(311)154-56-37-84-260(154)200(316)138(50-27-31-80-211)233-159(272)102-226-173(289)143(95-120-99-224-126-46-23-22-45-124(120)126)247-179(295)131(52-33-82-222-206(216)217)238-187(303)142(90-115-39-16-13-17-40-115)246-189(305)144(96-121-100-220-107-228-121)248-181(297)134(68-73-162(277)278)239-184(300)137(76-88-322-12)242-192(308)151(106-266)256-188(304)141(245-172(288)125(212)104-264)91-118-58-62-122(267)63-59-118/h13-23,39-46,58-65,99-100,107-114,125,127-155,166-168,224,264-268H,24-38,47-57,66-98,101-106,208-212H2,1-12H3,(H2,213,269)(H,220,228)(H,225,290)(H,226,289)(H,227,313)(H,229,270)(H,230,291)(H,231,307)(H,232,271)(H,233,272)(H,234,286)(H,235,285)(H,236,292)(H,237,293)(H,238,303)(H,239,300)(H,240,302)(H,241,306)(H,242,308)(H,243,314)(H,244,294)(H,245,288)(H,246,305)(H,247,295)(H,248,297)(H,249,296)(H,250,309)(H,251,310)(H,252,287)(H,253,315)(H,254,298)(H,255,299)(H,256,304)(H,257,301)(H,258,311)(H,259,312)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,320,321)(H4,214,215,221)(H4,216,217,222)(H4,218,219,223)/t112-,113-,114-,125-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,154-,155-,166-,167-,168-/m0/s1" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corticotrophine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB01285" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corticotrofina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ACTH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "IDLFZVILOHSSID-OVLDLUHVSA-N" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C02017" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-prolyl-L-alpha-aspartylglycyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alpha-glutamyl-L-seryl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-prolyl-L-leucyl-L-alpha-glutamyl-L-phenylalanine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "4538.25937" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Corticotropin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "adrenocorticotropin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Adrenocorticotropic hormone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) SubClassOf [peptide hormone](http://purl.obolibrary.org/obo/CHEBI_25905) + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) SubClassOf [biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33694) + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) SubClassOf [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) + +- [corticotropin](http://purl.obolibrary.org/obo/CHEBI_3892) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [diagnostic agent](http://purl.obolibrary.org/obo/CHEBI_33295) + + + +### cranial salt gland `http://purl.obolibrary.org/obo/UBERON_0004759` +#### Removed +- [cranial salt gland](http://purl.obolibrary.org/obo/UBERON_0004759) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A salt gland located in the cranium or head region." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" + +- [cranial salt gland](http://purl.obolibrary.org/obo/UBERON_0004759) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [cranial salt gland](http://purl.obolibrary.org/obo/UBERON_0004759) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0004759" + +- [cranial salt gland](http://purl.obolibrary.org/obo/UBERON_0004759) [label](http://www.w3.org/2000/01/rdf-schema#label) "cranial salt gland" + +- [cranial salt gland](http://purl.obolibrary.org/obo/UBERON_0004759) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [organ_slim](http://purl.obolibrary.org/obo/uberon/core#organ_slim) + +- Class: [cranial salt gland](http://purl.obolibrary.org/obo/UBERON_0004759) + +- [cranial salt gland](http://purl.obolibrary.org/obo/UBERON_0004759) EquivalentTo [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [head](http://purl.obolibrary.org/obo/UBERON_0000033)) + +- [cranial salt gland](http://purl.obolibrary.org/obo/UBERON_0004759) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [head](http://purl.obolibrary.org/obo/UBERON_0000033) + +- [cranial salt gland](http://purl.obolibrary.org/obo/UBERON_0004759) SubClassOf [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) + + + +### created_by `ttp://www.geneontology.org/formats/oboInOwl#created_by` +#### Removed +- AnnotationProperty: [created_by](ttp://www.geneontology.org/formats/oboInOwl#created_by) + + + +### crustacean metabolite `http://purl.obolibrary.org/obo/CHEBI_83039` +#### Removed +- [crustacean metabolite](http://purl.obolibrary.org/obo/CHEBI_83039) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [crustacean metabolite](http://purl.obolibrary.org/obo/CHEBI_83039) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill." + +- [crustacean metabolite](http://purl.obolibrary.org/obo/CHEBI_83039) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [crustacean metabolite](http://purl.obolibrary.org/obo/CHEBI_83039) [label](http://www.w3.org/2000/01/rdf-schema#label) "crustacean metabolite" + +- [crustacean metabolite](http://purl.obolibrary.org/obo/CHEBI_83039) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "crustacean metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [crustacean metabolite](http://purl.obolibrary.org/obo/CHEBI_83039) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:83039" + +- Class: [crustacean metabolite](http://purl.obolibrary.org/obo/CHEBI_83039) + +- [crustacean metabolite](http://purl.obolibrary.org/obo/CHEBI_83039) SubClassOf [animal metabolite](http://purl.obolibrary.org/obo/CHEBI_75767) + + + +### cyclic compound `http://purl.obolibrary.org/obo/CHEBI_33595` +#### Removed +- [cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33595) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33595) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33595) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33595" + +- [cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33595) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33595) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cyclic_compound" + +- [cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33595) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any molecule that consists of a series of atoms joined together to form a ring." + +- [cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33595) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33595) [label](http://www.w3.org/2000/01/rdf-schema#label) "cyclic compound" + +- Class: [cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33595) + +- [cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33595) SubClassOf [molecule](http://purl.obolibrary.org/obo/CHEBI_25367) + + + +### cyclic ketone `http://purl.obolibrary.org/obo/CHEBI_3992` +#### Removed +- [cyclic ketone](http://purl.obolibrary.org/obo/CHEBI_3992) [label](http://www.w3.org/2000/01/rdf-schema#label) "cyclic ketone" + +- [cyclic ketone](http://purl.obolibrary.org/obo/CHEBI_3992) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [cyclic ketone](http://purl.obolibrary.org/obo/CHEBI_3992) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C02019" + +- [cyclic ketone](http://purl.obolibrary.org/obo/CHEBI_3992) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Cyclic ketone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [cyclic ketone](http://purl.obolibrary.org/obo/CHEBI_3992) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:3992" + +- [cyclic ketone](http://purl.obolibrary.org/obo/CHEBI_3992) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [cyclic ketone](http://purl.obolibrary.org/obo/CHEBI_3992) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cyclic ketones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- Class: [cyclic ketone](http://purl.obolibrary.org/obo/CHEBI_3992) + +- [cyclic ketone](http://purl.obolibrary.org/obo/CHEBI_3992) SubClassOf [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) + + + +### cyclic organic group `http://purl.obolibrary.org/obo/CHEBI_52845` +#### Removed +- [cyclic organic group](http://purl.obolibrary.org/obo/CHEBI_52845) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [cyclic organic group](http://purl.obolibrary.org/obo/CHEBI_52845) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An organic group that consists of a closed ring. It may be a substituent or a skeleton." + +- [cyclic organic group](http://purl.obolibrary.org/obo/CHEBI_52845) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:52845" + +- [cyclic organic group](http://purl.obolibrary.org/obo/CHEBI_52845) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cyclic organic groups" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cyclic organic group](http://purl.obolibrary.org/obo/CHEBI_52845) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [cyclic organic group](http://purl.obolibrary.org/obo/CHEBI_52845) [label](http://www.w3.org/2000/01/rdf-schema#label) "cyclic organic group" + +- Class: [cyclic organic group](http://purl.obolibrary.org/obo/CHEBI_52845) + +- [cyclic organic group](http://purl.obolibrary.org/obo/CHEBI_52845) SubClassOf [organic group](http://purl.obolibrary.org/obo/CHEBI_33247) + + + +### cyclic peptide `http://purl.obolibrary.org/obo/CHEBI_23449` +#### Removed +- [cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_23449) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "peptide cyclique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_23449) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cyclic peptides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_23449) [label](http://www.w3.org/2000/01/rdf-schema#label) "cyclic peptide" + +- [cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_23449) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Cyclopeptid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_23449) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Zyklopeptid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_23449) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_23449) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "peptido ciclico" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_23449) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:23449" + +- [cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_23449) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_23449) + +- [cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_23449) SubClassOf [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) + + + +### d-block element atom `http://purl.obolibrary.org/obo/CHEBI_33561` +#### Removed +- [d-block element atom](http://purl.obolibrary.org/obo/CHEBI_33561) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [d-block element atom](http://purl.obolibrary.org/obo/CHEBI_33561) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [d-block element atom](http://purl.obolibrary.org/obo/CHEBI_33561) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "d-block elements" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [d-block element atom](http://purl.obolibrary.org/obo/CHEBI_33561) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "d-block element" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [d-block element atom](http://purl.obolibrary.org/obo/CHEBI_33561) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33561" + +- [d-block element atom](http://purl.obolibrary.org/obo/CHEBI_33561) [label](http://www.w3.org/2000/01/rdf-schema#label) "d-block element atom" + +- Class: [d-block element atom](http://purl.obolibrary.org/obo/CHEBI_33561) + +- [d-block element atom](http://purl.obolibrary.org/obo/CHEBI_33561) SubClassOf [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) + + + +### d-block molecular entity `http://purl.obolibrary.org/obo/CHEBI_33676` +#### Removed +- [d-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33676) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element." + +- [d-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33676) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [d-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33676) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [d-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33676) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "d-block molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [d-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33676) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33676" + +- [d-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33676) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "d-block compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [d-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33676) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "d-block molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [d-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33676) [label](http://www.w3.org/2000/01/rdf-schema#label) "d-block molecular entity" + +- Class: [d-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33676) + +- [d-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33676) SubClassOf [transition element molecular entity](http://purl.obolibrary.org/obo/CHEBI_33497) + +- [d-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33676) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [d-block element atom](http://purl.obolibrary.org/obo/CHEBI_33561) + + + +### decidual natural killer cell, human `http://purl.obolibrary.org/obo/CL_0002343` +#### Removed +- [decidual natural killer cell, human](http://purl.obolibrary.org/obo/CL_0002343) EquivalentTo [mature natural killer cell](http://purl.obolibrary.org/obo/CL_0000824) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [galectin-1](http://purl.obolibrary.org/obo/PR_000009766)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) + +- [decidual natural killer cell, human](http://purl.obolibrary.org/obo/CL_0002343) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483) + +#### Added +- [decidual natural killer cell, human](http://purl.obolibrary.org/obo/CL_0002343) EquivalentTo [mature natural killer cell](http://purl.obolibrary.org/obo/CL_0000824) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [galectin-1](http://purl.obolibrary.org/obo/PR_000009766)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) + +- [decidual natural killer cell, human](http://purl.obolibrary.org/obo/CL_0002343) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483) + + +### dendritic cell `http://purl.obolibrary.org/obo/CL_0000451` +#### Removed +- [dendritic cell](http://purl.obolibrary.org/obo/CL_0000451) EquivalentTo [leukocyte](http://purl.obolibrary.org/obo/CL_0000738) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [mononucleate](http://purl.obolibrary.org/obo/PATO_0001407)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [cytokine production](http://purl.obolibrary.org/obo/GO_0001816)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [antigen processing and presentation of peptide or polysaccharide antigen via MHC class II](http://purl.obolibrary.org/obo/GO_0002504)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [antigen processing and presentation](http://purl.obolibrary.org/obo/GO_0019882)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [regulation of T cell differentiation](http://purl.obolibrary.org/obo/GO_0045580)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) + +- [dendritic cell](http://purl.obolibrary.org/obo/CL_0000451) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [dendritic cell](http://purl.obolibrary.org/obo/CL_0000451) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + +- [dendritic cell](http://purl.obolibrary.org/obo/CL_0000451) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [dendritic cell](http://purl.obolibrary.org/obo/CL_0000451) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [dendritic cell](http://purl.obolibrary.org/obo/CL_0000451) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +#### Added +- [dendritic cell](http://purl.obolibrary.org/obo/CL_0000451) EquivalentTo [leukocyte](http://purl.obolibrary.org/obo/CL_0000738) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [mononucleate](http://purl.obolibrary.org/obo/PATO_0001407)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [cytokine production](http://purl.obolibrary.org/obo/GO_0001816)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [antigen processing and presentation of peptide or polysaccharide antigen via MHC class II](http://purl.obolibrary.org/obo/GO_0002504)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [antigen processing and presentation](http://purl.obolibrary.org/obo/GO_0019882)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [regulation of T cell differentiation](http://purl.obolibrary.org/obo/GO_0045580)) + +- [dendritic cell](http://purl.obolibrary.org/obo/CL_0000451) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [dendritic cell](http://purl.obolibrary.org/obo/CL_0000451) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [dendritic cell](http://purl.obolibrary.org/obo/CL_0000451) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [dendritic cell](http://purl.obolibrary.org/obo/CL_0000451) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + +- [dendritic cell](http://purl.obolibrary.org/obo/CL_0000451) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + + +### deoxyribonucleic acid `http://purl.obolibrary.org/obo/CHEBI_16991` +#### Removed +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "desoxyribose nucleic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00039" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "DNAn" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "thymus nucleic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:33698" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "DNA" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Deoxyribonucleic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:9007-49-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13302" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms." + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [label](http://www.w3.org/2000/01/rdf-schema#label) "deoxyribonucleic acid" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(Deoxyribonucleotide)m" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:9007-49-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Desoxyribonukleinsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "DNS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "DNAn+1" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "deoxyribonucleic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "DNA" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(Deoxyribonucleotide)n" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(Deoxyribonucleotide)n+m" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "deoxyribonucleic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:4291" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:16991" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "DNA" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:21123" + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [canonical deoxyribonucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50298) + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [canonical deoxyribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33793) + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) SubClassOf [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [deoxyribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_16991) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + + + +### depends on `http://purl.obolibrary.org/obo/RO_0002502` +#### Removed +- [depends on](http://purl.obolibrary.org/obo/RO_0002502) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [depends on](http://purl.obolibrary.org/obo/RO_0002502) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### detoxification of iron ion `http://purl.obolibrary.org/obo/GO_1990461` +#### Removed +- [detoxification of iron ion](http://purl.obolibrary.org/obo/GO_1990461) SubClassOf [detoxification of inorganic compound](http://purl.obolibrary.org/obo/GO_0061687) + +#### Added +- [detoxification of iron ion](http://purl.obolibrary.org/obo/GO_1990461) SubClassOf [detoxification](http://purl.obolibrary.org/obo/GO_0098754) + + +### developmentally contributes to `http://purl.obolibrary.org/obo/RO_0002255` +#### Removed +- [developmentally contributes to](http://purl.obolibrary.org/obo/RO_0002255) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [developmentally contributes to](http://purl.obolibrary.org/obo/RO_0002255) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### developmentally induced by `http://purl.obolibrary.org/obo/RO_0002256` +#### Removed +- [developmentally induced by](http://purl.obolibrary.org/obo/RO_0002256) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +- [developmentally induced by](http://purl.obolibrary.org/obo/RO_0002256) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland" + +- [developmentally induced by](http://purl.obolibrary.org/obo/RO_0002256) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Melissa Haendel" + +#### Added +- [developmentally induced by](http://purl.obolibrary.org/obo/RO_0002256) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + +- [developmentally induced by](http://purl.obolibrary.org/obo/RO_0002256) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0001-9114-8737](https://orcid.org/0000-0001-9114-8737) + +- [developmentally induced by](http://purl.obolibrary.org/obo/RO_0002256) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### developmentally induces `http://purl.obolibrary.org/obo/RO_0002257` +#### Removed +- [developmentally induces](http://purl.obolibrary.org/obo/RO_0002257) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [developmentally induces](http://purl.obolibrary.org/obo/RO_0002257) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### developmentally preceded by `http://purl.obolibrary.org/obo/RO_0002258` +#### Removed +- [developmentally preceded by](http://purl.obolibrary.org/obo/RO_0002258) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [developmentally preceded by](http://purl.obolibrary.org/obo/RO_0002258) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### developmentally related to `http://purl.obolibrary.org/obo/RO_0002324` +#### Removed +- [developmentally related to](http://purl.obolibrary.org/obo/RO_0002324) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [developmentally related to](http://purl.obolibrary.org/obo/RO_0002324) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### developmentally replaces `http://purl.obolibrary.org/obo/RO_0002285` +#### Removed +- [developmentally replaces](http://purl.obolibrary.org/obo/RO_0002285) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [developmentally replaces](http://purl.obolibrary.org/obo/RO_0002285) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### developmentally succeeded by `http://purl.obolibrary.org/obo/RO_0002286` +#### Removed +- [developmentally succeeded by](http://purl.obolibrary.org/obo/RO_0002286) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [developmentally succeeded by](http://purl.obolibrary.org/obo/RO_0002286) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### develops from `http://purl.obolibrary.org/obo/RO_0002202` +#### Removed +- [develops from](http://purl.obolibrary.org/obo/RO_0002202) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall"@en + +- [develops from](http://purl.obolibrary.org/obo/RO_0002202) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Terry Meehan"@en + +- [develops from](http://purl.obolibrary.org/obo/RO_0002202) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland"@en + +- [develops from](http://purl.obolibrary.org/obo/RO_0002202) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Melissa Haendel" + +#### Added +- [develops from](http://purl.obolibrary.org/obo/RO_0002202) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0003-1980-3228](https://orcid.org/0000-0003-1980-3228) + +- [develops from](http://purl.obolibrary.org/obo/RO_0002202) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0001-9114-8737](https://orcid.org/0000-0001-9114-8737) + +- [develops from](http://purl.obolibrary.org/obo/RO_0002202) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + +- [develops from](http://purl.obolibrary.org/obo/RO_0002202) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + + +### develops from part of `http://purl.obolibrary.org/obo/RO_0002225` +#### Removed +- [develops from part of](http://purl.obolibrary.org/obo/RO_0002225) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [develops from part of](http://purl.obolibrary.org/obo/RO_0002225) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### develops in `http://purl.obolibrary.org/obo/RO_0002226` +#### Removed +- [develops in](http://purl.obolibrary.org/obo/RO_0002226) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [develops in](http://purl.obolibrary.org/obo/RO_0002226) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### develops into `http://purl.obolibrary.org/obo/RO_0002203` +#### Removed +- [develops into](http://purl.obolibrary.org/obo/RO_0002203) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall"@en + +- [develops into](http://purl.obolibrary.org/obo/RO_0002203) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland"@en + +- [develops into](http://purl.obolibrary.org/obo/RO_0002203) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Terry Meehan"@en + +#### Added +- [develops into](http://purl.obolibrary.org/obo/RO_0002203) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + +- [develops into](http://purl.obolibrary.org/obo/RO_0002203) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0003-1980-3228](https://orcid.org/0000-0003-1980-3228) + +- [develops into](http://purl.obolibrary.org/obo/RO_0002203) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### device utilizes material `http://purl.obolibrary.org/obo/RO_0017001` +#### Removed +- [device utilizes material](http://purl.obolibrary.org/obo/RO_0017001) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "https://orcid.org/0000-0001-9625-1899" + +- [device utilizes material](http://purl.obolibrary.org/obo/RO_0017001) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "https://orcid.org/0000-0003-2620-0345" + +#### Added +- [device utilizes material](http://purl.obolibrary.org/obo/RO_0017001) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0001-9625-1899](https://orcid.org/0000-0001-9625-1899) + +- [device utilizes material](http://purl.obolibrary.org/obo/RO_0017001) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0003-2620-0345](https://orcid.org/0000-0003-2620-0345) + + +### diagnostic agent `http://purl.obolibrary.org/obo/CHEBI_33295` +#### Removed +- [diagnostic agent](http://purl.obolibrary.org/obo/CHEBI_33295) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33295" + +- [diagnostic agent](http://purl.obolibrary.org/obo/CHEBI_33295) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [diagnostic agent](http://purl.obolibrary.org/obo/CHEBI_33295) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A substance administered to aid diagnosis of a disease." + +- [diagnostic agent](http://purl.obolibrary.org/obo/CHEBI_33295) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [diagnostic agent](http://purl.obolibrary.org/obo/CHEBI_33295) [label](http://www.w3.org/2000/01/rdf-schema#label) "diagnostic agent" + +- [diagnostic agent](http://purl.obolibrary.org/obo/CHEBI_33295) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "diagnostic aid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [diagnostic agent](http://purl.obolibrary.org/obo/CHEBI_33295) + +- [diagnostic agent](http://purl.obolibrary.org/obo/CHEBI_33295) SubClassOf [pharmaceutical](http://purl.obolibrary.org/obo/CHEBI_52217) + + + +### diatomic oxygen `http://purl.obolibrary.org/obo/CHEBI_33263` +#### Removed +- [diatomic oxygen](http://purl.obolibrary.org/obo/CHEBI_33263) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "31.98983" + +- [diatomic oxygen](http://purl.obolibrary.org/obo/CHEBI_33263) [label](http://www.w3.org/2000/01/rdf-schema#label) "diatomic oxygen" + +- [diatomic oxygen](http://purl.obolibrary.org/obo/CHEBI_33263) [formula](http://purl.obolibrary.org/obo/chebi/formula) "O2" + +- [diatomic oxygen](http://purl.obolibrary.org/obo/CHEBI_33263) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [diatomic oxygen](http://purl.obolibrary.org/obo/CHEBI_33263) [mass](http://purl.obolibrary.org/obo/chebi/mass) "31.999" + +- [diatomic oxygen](http://purl.obolibrary.org/obo/CHEBI_33263) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33263" + +- [diatomic oxygen](http://purl.obolibrary.org/obo/CHEBI_33263) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [diatomic oxygen](http://purl.obolibrary.org/obo/CHEBI_33263) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [diatomic oxygen](http://purl.obolibrary.org/obo/CHEBI_33263) + +- [diatomic oxygen](http://purl.obolibrary.org/obo/CHEBI_33263) SubClassOf [elemental oxygen](http://purl.obolibrary.org/obo/CHEBI_33262) + + + +### diazole `http://purl.obolibrary.org/obo/CHEBI_23677` +#### Removed +- [diazole](http://purl.obolibrary.org/obo/CHEBI_23677) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [diazole](http://purl.obolibrary.org/obo/CHEBI_23677) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An azole that is either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring." + +- [diazole](http://purl.obolibrary.org/obo/CHEBI_23677) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "diazoles" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [diazole](http://purl.obolibrary.org/obo/CHEBI_23677) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [diazole](http://purl.obolibrary.org/obo/CHEBI_23677) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "diazoles" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [diazole](http://purl.obolibrary.org/obo/CHEBI_23677) [label](http://www.w3.org/2000/01/rdf-schema#label) "diazole" + +- [diazole](http://purl.obolibrary.org/obo/CHEBI_23677) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [diazole](http://purl.obolibrary.org/obo/CHEBI_23677) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:23677" + +- Class: [diazole](http://purl.obolibrary.org/obo/CHEBI_23677) + +- [diazole](http://purl.obolibrary.org/obo/CHEBI_23677) SubClassOf [azole](http://purl.obolibrary.org/obo/CHEBI_68452) + + + +### dicarboxylic acid `http://purl.obolibrary.org/obo/CHEBI_35692` +#### Removed +- [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35692" + +- [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Dicarboxylic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C02028" + +- [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:4501" + +- [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any carboxylic acid containing two carboxy groups." + +- [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dicarboxylic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:36172" + +- [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) [label](http://www.w3.org/2000/01/rdf-schema#label) "dicarboxylic acid" + +- [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23692" + +- Class: [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) + +- [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [dicarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35693) + +- [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) SubClassOf [dicarboxylic acids and O-substituted derivatives](http://purl.obolibrary.org/obo/CHEBI_131927) + +- [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) SubClassOf [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) + + + +### dicarboxylic acid anion `http://purl.obolibrary.org/obo/CHEBI_35693` +#### Removed +- [dicarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35693) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [dicarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35693) [label](http://www.w3.org/2000/01/rdf-schema#label) "dicarboxylic acid anion" + +- [dicarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35693) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dicarboxylic acid anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dicarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35693) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [dicarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35693) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35693" + +- [dicarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35693) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dicarboxylic acid anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dicarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35693) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) + +- [dicarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35693) SubClassOf [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) + + + +### dicarboxylic acid biosynthetic process `http://purl.obolibrary.org/obo/GO_0043650` +#### Removed +- [dicarboxylic acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0043650) SubClassOf [carboxylic acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046394) + +#### Added +- [dicarboxylic acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0043650) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### dicarboxylic acid catabolic process `http://purl.obolibrary.org/obo/GO_0043649` +#### Removed +- [dicarboxylic acid catabolic process](http://purl.obolibrary.org/obo/GO_0043649) SubClassOf [carboxylic acid catabolic process](http://purl.obolibrary.org/obo/GO_0046395) + +#### Added +- [dicarboxylic acid catabolic process](http://purl.obolibrary.org/obo/GO_0043649) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### dicarboxylic acid dianion `http://purl.obolibrary.org/obo/CHEBI_28965` +#### Removed +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [label](http://www.w3.org/2000/01/rdf-schema#label) "dicarboxylic acid dianion" + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid." + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23688" + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dicarboxylic acid dianions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23689" + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dicarboxylate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-2" + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13632" + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [mass](http://purl.obolibrary.org/obo/chebi/mass) "88.019" + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:38711" + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a dicarboxylate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dicarboxylates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2O4R" + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "87.97966" + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:28965" + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[O-]C(=O)[*]C([O-])=O" + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dicarboxylic acid dianion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) SubClassOf [carboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_38716) + +- [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) SubClassOf [dicarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35693) + + + +### dicarboxylic acid transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0005310` +#### Removed +- [dicarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005310) [label](http://www.w3.org/2000/01/rdf-schema#label) "dicarboxylic acid transmembrane transporter activity" + +- [dicarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005310) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "sodium:dicarboxylate/tricarboxylate symporter activity" + +- [dicarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005310) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dicarboxylic acid permease activity" + +- [dicarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005310) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-1614546" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "Sulfate is exported to the cytosol in exchange for dicarboxylate" + +- [dicarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005310) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0005310" + +- [dicarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005310) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0005312" + +- [dicarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005310) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0015365" + +- [dicarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005310) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "dicarboxylate carrier" + +- [dicarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005310) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dicarboxylate (succinate/fumarate/malate) antiporter activity" + +- [dicarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005310) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-372843" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]" + +- [dicarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005310) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [dicarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005310) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- Class: [dicarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005310) + +- [dicarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005310) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692)) + +- [dicarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005310) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [dicarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_35692) + +- [dicarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005310) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [dicarboxylic acid transport](http://purl.obolibrary.org/obo/GO_0006835) + +- [dicarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005310) SubClassOf [organic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005342) + + + +### dicarboxylic acid transport `http://purl.obolibrary.org/obo/GO_0006835` +#### Removed +- [dicarboxylic acid transport](http://purl.obolibrary.org/obo/GO_0006835) SubClassOf [carboxylic acid transport](http://purl.obolibrary.org/obo/GO_0046942) + +#### Added +- [dicarboxylic acid transport](http://purl.obolibrary.org/obo/GO_0006835) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### dicarboxylic acids and O-substituted derivatives `http://purl.obolibrary.org/obo/CHEBI_131927` +#### Removed +- [dicarboxylic acids and O-substituted derivatives](http://purl.obolibrary.org/obo/CHEBI_131927) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens." + +- [dicarboxylic acids and O-substituted derivatives](http://purl.obolibrary.org/obo/CHEBI_131927) [label](http://www.w3.org/2000/01/rdf-schema#label) "dicarboxylic acids and O-substituted derivatives" + +- [dicarboxylic acids and O-substituted derivatives](http://purl.obolibrary.org/obo/CHEBI_131927) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dicarboxylic acids and derivatives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dicarboxylic acids and O-substituted derivatives](http://purl.obolibrary.org/obo/CHEBI_131927) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [dicarboxylic acids and O-substituted derivatives](http://purl.obolibrary.org/obo/CHEBI_131927) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [dicarboxylic acids and O-substituted derivatives](http://purl.obolibrary.org/obo/CHEBI_131927) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:131927" + +- Class: [dicarboxylic acids and O-substituted derivatives](http://purl.obolibrary.org/obo/CHEBI_131927) + +- [dicarboxylic acids and O-substituted derivatives](http://purl.obolibrary.org/obo/CHEBI_131927) SubClassOf [carbonyl compound](http://purl.obolibrary.org/obo/CHEBI_36586) + + + +### dihydrogenphosphate `http://purl.obolibrary.org/obo/CHEBI_39745` +#### Removed +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dihydroxidodioxidophosphate(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:39739" + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:1999" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [label](http://www.w3.org/2000/01/rdf-schema#label) "dihydrogenphosphate" + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "DIHYDROGENPHOSPHATE ION" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:29137" + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [formula](http://purl.obolibrary.org/obo/chebi/formula) "H2O4P" + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "H2PO4(-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dihydrogentetraoxophosphate(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dihydrogenphosphate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [mass](http://purl.obolibrary.org/obo/chebi/mass) "96.98724" + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-1" + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H]OP([O-])(=O)O[H]" + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dihydrogen(tetraoxidophosphate)(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "96.96962" + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:39745" + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated." + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB02831" + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[PO2(OH)2](-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "NBIIXXVUZAFLBC-UHFFFAOYSA-M" + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dihydrogentetraoxophosphate(V)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:2HP" + +- Class: [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) SubClassOf [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) + +- [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) SubClassOf [monovalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79389) + + + +### dioxygen `http://purl.obolibrary.org/obo/CHEBI_15379` +#### Removed +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16977326" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13416" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:OXYGEN-MOLECULE" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00007" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "molecular oxygen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7782-44-7" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Oxygen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [formula](http://purl.obolibrary.org/obo/chebi/formula) "O2" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Disauerstoff" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Oxygen" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:30491" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10906528" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "OXYGEN MOLECULE" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "O2" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9463773" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18210929" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:15379" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [label](http://www.w3.org/2000/01/rdf-schema#label) "dioxygen" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "E 948" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:485" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "MYMOFIZGZYHOMD-UHFFFAOYSA-N" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23833" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "E-948" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[OO]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MolBase" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:10745" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7782-44-7" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:7860" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7782-44-7" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "O2" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:25366" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0001377" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MolBase:750" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "E948" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D00003" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "O2" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19840863" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [mass](http://purl.obolibrary.org/obo/chebi/mass) "31.998" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:OXY" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:7710549" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18638417" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dioxygene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "O=O" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:44742" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "31.98983" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/O2/c1-2" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dioxygen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [micronutrient](http://purl.obolibrary.org/obo/CHEBI_27027) + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [reagent](http://purl.obolibrary.org/obo/CHEBI_33893) + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [food packaging gas](http://purl.obolibrary.org/obo/CHEBI_77974) + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [anti-inflammatory drug](http://purl.obolibrary.org/obo/CHEBI_35472) + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [oxidising agent](http://purl.obolibrary.org/obo/CHEBI_63248) + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) SubClassOf [gas molecular entity](http://purl.obolibrary.org/obo/CHEBI_138675) + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) SubClassOf [diatomic oxygen](http://purl.obolibrary.org/obo/CHEBI_33263) + +- [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) SubClassOf [elemental molecule](http://purl.obolibrary.org/obo/CHEBI_25362) + + + +### dipolar compound `http://purl.obolibrary.org/obo/CHEBI_51151` +#### Removed +- [dipolar compound](http://purl.obolibrary.org/obo/CHEBI_51151) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dipolar compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dipolar compound](http://purl.obolibrary.org/obo/CHEBI_51151) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:51151" + +- [dipolar compound](http://purl.obolibrary.org/obo/CHEBI_51151) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [dipolar compound](http://purl.obolibrary.org/obo/CHEBI_51151) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [dipolar compound](http://purl.obolibrary.org/obo/CHEBI_51151) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case." + +- [dipolar compound](http://purl.obolibrary.org/obo/CHEBI_51151) [label](http://www.w3.org/2000/01/rdf-schema#label) "dipolar compound" + +- Class: [dipolar compound](http://purl.obolibrary.org/obo/CHEBI_51151) + +- [dipolar compound](http://purl.obolibrary.org/obo/CHEBI_51151) SubClassOf [organic molecule](http://purl.obolibrary.org/obo/CHEBI_72695) + + + +### directly develops from `http://purl.obolibrary.org/obo/RO_0002207` +#### Removed +- [directly develops from](http://purl.obolibrary.org/obo/RO_0002207) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +- [directly develops from](http://purl.obolibrary.org/obo/RO_0002207) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland" + +- [directly develops from](http://purl.obolibrary.org/obo/RO_0002207) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "has developmental precursor" + +#### Added +- [directly develops from](http://purl.obolibrary.org/obo/RO_0002207) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + +- [directly develops from](http://purl.obolibrary.org/obo/RO_0002207) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "has developmental precursor" + +- [directly develops from](http://purl.obolibrary.org/obo/RO_0002207) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + + +### directly negatively regulates activity of `http://purl.obolibrary.org/obo/RO_0002449` +#### Removed +- [directly negatively regulates activity of](http://purl.obolibrary.org/obo/RO_0002449) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +- [directly negatively regulates activity of](http://purl.obolibrary.org/obo/RO_0002449) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Vasundra Touré" + +#### Added +- [directly negatively regulates activity of](http://purl.obolibrary.org/obo/RO_0002449) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0003-4639-4431](https://orcid.org/0000-0003-4639-4431) + +- [directly negatively regulates activity of](http://purl.obolibrary.org/obo/RO_0002449) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### directly positively regulates activity of `http://purl.obolibrary.org/obo/RO_0002450` +#### Removed +- [directly positively regulates activity of](http://purl.obolibrary.org/obo/RO_0002450) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Vasundra Touré" + +- [directly positively regulates activity of](http://purl.obolibrary.org/obo/RO_0002450) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [directly positively regulates activity of](http://purl.obolibrary.org/obo/RO_0002450) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0003-4639-4431](https://orcid.org/0000-0003-4639-4431) + +- [directly positively regulates activity of](http://purl.obolibrary.org/obo/RO_0002450) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### directly regulates `http://purl.obolibrary.org/obo/RO_0002578` +#### Removed +- [directly regulates](http://purl.obolibrary.org/obo/RO_0002578) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [directly regulates](http://purl.obolibrary.org/obo/RO_0002578) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### directly regulates activity of `http://purl.obolibrary.org/obo/RO_0002448` +#### Removed +- [directly regulates activity of](http://purl.obolibrary.org/obo/RO_0002448) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Vasundra Touré" + +- [directly regulates activity of](http://purl.obolibrary.org/obo/RO_0002448) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [directly regulates activity of](http://purl.obolibrary.org/obo/RO_0002448) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0003-4639-4431](https://orcid.org/0000-0003-4639-4431) + +- [directly regulates activity of](http://purl.obolibrary.org/obo/RO_0002448) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### divalent inorganic anion `http://purl.obolibrary.org/obo/CHEBI_79388` +#### Removed +- [divalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79388) [label](http://www.w3.org/2000/01/rdf-schema#label) "divalent inorganic anion" + +- [divalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79388) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any inorganic anion with a valency of two." + +- [divalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79388) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [divalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79388) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "divalent inorganic anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [divalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79388) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [divalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79388) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:79388" + +- Class: [divalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79388) + +- [divalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79388) SubClassOf [inorganic anion](http://purl.obolibrary.org/obo/CHEBI_24834) + + + +### divalent inorganic cation `http://purl.obolibrary.org/obo/CHEBI_64641` +#### Removed +- [divalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_64641) [label](http://www.w3.org/2000/01/rdf-schema#label) "divalent inorganic cation" + +- [divalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_64641) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [divalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_64641) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [divalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_64641) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:64641" + +- [divalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_64641) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An inorganic cation with a valency of two." + +- Class: [divalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_64641) + +- [divalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_64641) SubClassOf [inorganic cation](http://purl.obolibrary.org/obo/CHEBI_36915) + + + +### divalent metal cation `http://purl.obolibrary.org/obo/CHEBI_60240` +#### Removed +- [divalent metal cation](http://purl.obolibrary.org/obo/CHEBI_60240) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:60240" + +- [divalent metal cation](http://purl.obolibrary.org/obo/CHEBI_60240) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [divalent metal cation](http://purl.obolibrary.org/obo/CHEBI_60240) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A metal cation with a valence of two." + +- [divalent metal cation](http://purl.obolibrary.org/obo/CHEBI_60240) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a divalent metal cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [divalent metal cation](http://purl.obolibrary.org/obo/CHEBI_60240) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [divalent metal cation](http://purl.obolibrary.org/obo/CHEBI_60240) [label](http://www.w3.org/2000/01/rdf-schema#label) "divalent metal cation" + +- Class: [divalent metal cation](http://purl.obolibrary.org/obo/CHEBI_60240) + +- [divalent metal cation](http://purl.obolibrary.org/obo/CHEBI_60240) SubClassOf [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) + +- [divalent metal cation](http://purl.obolibrary.org/obo/CHEBI_60240) SubClassOf [divalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_64641) + + + +### donor `http://purl.obolibrary.org/obo/CHEBI_17891` +#### Removed +- [donor](http://purl.obolibrary.org/obo/CHEBI_17891) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Donator" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [donor](http://purl.obolibrary.org/obo/CHEBI_17891) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:17891" + +- [donor](http://purl.obolibrary.org/obo/CHEBI_17891) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "donneur" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [donor](http://purl.obolibrary.org/obo/CHEBI_17891) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01351" + +- [donor](http://purl.obolibrary.org/obo/CHEBI_17891) [label](http://www.w3.org/2000/01/rdf-schema#label) "donor" + +- [donor](http://purl.obolibrary.org/obo/CHEBI_17891) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity." + +- [donor](http://purl.obolibrary.org/obo/CHEBI_17891) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:4697" + +- [donor](http://purl.obolibrary.org/obo/CHEBI_17891) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [donor](http://purl.obolibrary.org/obo/CHEBI_17891) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [donor](http://purl.obolibrary.org/obo/CHEBI_17891) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14202" + +- [donor](http://purl.obolibrary.org/obo/CHEBI_17891) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Donor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- Class: [donor](http://purl.obolibrary.org/obo/CHEBI_17891) + +- [donor](http://purl.obolibrary.org/obo/CHEBI_17891) SubClassOf [chemical role](http://purl.obolibrary.org/obo/CHEBI_51086) + + + +### dopamine `http://purl.obolibrary.org/obo/CHEBI_18243` +#### Removed +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Deoxyepinephrine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-(2-aminoethyl)pyrocatechol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus:" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dopamina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [mass](http://purl.obolibrary.org/obo/chebi/mass) "153.17840" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "4-(2-aminoethyl)benzene-1,2-diol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Dopamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-(2-Aminoethyl)benzene-1,2-diol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "2-(3,4-dihydroxyphenyl)ethylamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "153.07898" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Dopamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "2-(3,4-dihydroxyphenyl)ethylamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C8H11NO2" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dopamina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/fbbt#INN) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dopaminum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:947" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB00988" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:1072822" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-(2-aminoethyl)-1,2-benzenediol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dopamine" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3-Hydroxytyramine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-(2-aminoethyl)catechol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:DOPAMINE" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-(2-Aminoethyl)-1,2-benzenediol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:11930" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [label](http://www.w3.org/2000/01/rdf-schema#label) "dopamine" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:1764" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NCCc1ccc(O)c(O)c1" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [SMILES](http://purl.obolibrary.org/obo/fbbt#SMILES) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "C8H11NO2" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [FORMULA](http://purl.obolibrary.org/obo/fbbt#FORMULA) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3-Hydroxytyramine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus:" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-(2-Aminoethyl)benzene-1,2-diol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:18243" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "2-(3,4-Dihydroxyphenyl)ethylamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11149432" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:11695" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "4-(2-aminoethyl)benzene-1,2-diol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23886" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-(2-aminoethyl)catechol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus:" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "2-(3,4-Dihydroxyphenyl)ethylamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3,4-Dihydroxyphenethylamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:43686" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Hydroxytyramin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dopamine" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/fbbt#INN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "VYFYYTLLBUKUHU-UHFFFAOYSA-N" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3,4-Dihydroxyphenethylamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-(2-aminoethyl)pyrocatechol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000073" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Deoxyepinephrine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "InChIKey=VYFYYTLLBUKUHU-UHFFFAOYSA-N" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [InChIKey](http://purl.obolibrary.org/obo/fbbt#InChIKey) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9422813" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-(2-Aminoethyl)-1,2-benzenediol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-(2-aminoethyl)-1,2-benzenediol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LINCS:LSM-4630" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00001408" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Hydroxytyramin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [InChI](http://purl.obolibrary.org/obo/fbbt#InChI) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dopamine" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C03758" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dopaminum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/fbbt#INN) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:51-61-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "NCCc1ccc(O)c(O)c1" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D07870" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14203" + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10629745" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- Class: [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) SubClassOf [catecholamine](http://purl.obolibrary.org/obo/CHEBI_33567) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [cardiotonic drug](http://purl.obolibrary.org/obo/CHEBI_38147) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [beta-adrenergic agonist](http://purl.obolibrary.org/obo/CHEBI_35522) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [dopaminergic agent](http://purl.obolibrary.org/obo/CHEBI_48560) + +- [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [sympathomimetic agent](http://purl.obolibrary.org/obo/CHEBI_35524) + + + +### dopamine binding `http://purl.obolibrary.org/obo/GO_0035240` +#### Removed +- [dopamine binding](http://purl.obolibrary.org/obo/GO_0035240) SubClassOf [cation binding](http://purl.obolibrary.org/obo/GO_0043169) + +#### Added +- [dopamine binding](http://purl.obolibrary.org/obo/GO_0035240) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### dopamine metabolic process `http://purl.obolibrary.org/obo/GO_0042417` +#### Removed +- [dopamine metabolic process](http://purl.obolibrary.org/obo/GO_0042417) SubClassOf [nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0006807) + +#### Added +- [dopamine metabolic process](http://purl.obolibrary.org/obo/GO_0042417) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### dopamine secretion, neurotransmission `http://purl.obolibrary.org/obo/GO_0061527` + +#### Added +- [dopamine secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061527) EquivalentTo [neurotransmitter secretion](http://purl.obolibrary.org/obo/GO_0007269) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905)) + + +### dopamine transport `http://purl.obolibrary.org/obo/GO_0015872` +#### Removed +- [dopamine transport](http://purl.obolibrary.org/obo/GO_0015872) SubClassOf [nitrogen compound transport](http://purl.obolibrary.org/obo/GO_0071705) + +#### Added +- [dopamine transport](http://purl.obolibrary.org/obo/GO_0015872) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### dopamine uptake `http://purl.obolibrary.org/obo/GO_0090494` +#### Removed +- [dopamine uptake](http://purl.obolibrary.org/obo/GO_0090494) SubClassOf [import into cell](http://purl.obolibrary.org/obo/GO_0098657) + +#### Added +- [dopamine uptake](http://purl.obolibrary.org/obo/GO_0090494) SubClassOf [has target end location](http://purl.obolibrary.org/obo/RO_0002339) some [intracellular anatomical structure](http://purl.obolibrary.org/obo/GO_0005622) + +- [dopamine uptake](http://purl.obolibrary.org/obo/GO_0090494) SubClassOf [has target start location](http://purl.obolibrary.org/obo/RO_0002338) some [extracellular region](http://purl.obolibrary.org/obo/GO_0005576) + + +### dopaminergic agent `http://purl.obolibrary.org/obo/CHEBI_48560` +#### Removed +- [dopaminergic agent](http://purl.obolibrary.org/obo/CHEBI_48560) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [dopaminergic agent](http://purl.obolibrary.org/obo/CHEBI_48560) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dopamine agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dopaminergic agent](http://purl.obolibrary.org/obo/CHEBI_48560) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dopamine agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dopaminergic agent](http://purl.obolibrary.org/obo/CHEBI_48560) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dopaminergic agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dopaminergic agent](http://purl.obolibrary.org/obo/CHEBI_48560) [label](http://www.w3.org/2000/01/rdf-schema#label) "dopaminergic agent" + +- [dopaminergic agent](http://purl.obolibrary.org/obo/CHEBI_48560) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons." + +- [dopaminergic agent](http://purl.obolibrary.org/obo/CHEBI_48560) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dopamine drug" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dopaminergic agent](http://purl.obolibrary.org/obo/CHEBI_48560) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dopamine drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dopaminergic agent](http://purl.obolibrary.org/obo/CHEBI_48560) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:48560" + +- [dopaminergic agent](http://purl.obolibrary.org/obo/CHEBI_48560) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [dopaminergic agent](http://purl.obolibrary.org/obo/CHEBI_48560) + +- [dopaminergic agent](http://purl.obolibrary.org/obo/CHEBI_48560) SubClassOf [neurotransmitter agent](http://purl.obolibrary.org/obo/CHEBI_35942) + + + +### dopaminium(1+) `http://purl.obolibrary.org/obo/CHEBI_59905` +#### Removed +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2/p+1" + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dopamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "VYFYYTLLBUKUHU-UHFFFAOYSA-O" + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "2-(3,4-dihydroxyphenyl)ethan-1-aminium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An ammonium ion that is the conjugate acid of dopamine; major species at pH 7.3." + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "154.08626" + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[NH3+]CCc1ccc(O)c(O)c1" + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) [mass](http://purl.obolibrary.org/obo/chebi/mass) "154.18640" + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) [label](http://www.w3.org/2000/01/rdf-schema#label) "dopaminium(1+)" + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dopaminium cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+1" + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C8H12NO2" + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:328863" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "2-(3,4-dihydroxyphenyl)ethanaminium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:59905" + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [dopamine](http://purl.obolibrary.org/obo/CHEBI_18243) + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) SubClassOf [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) + +- [dopaminium(1+)](http://purl.obolibrary.org/obo/CHEBI_59905) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + + + +### double negative memory B cell `http://purl.obolibrary.org/obo/CL_0000981` +#### Removed +- [double negative memory B cell](http://purl.obolibrary.org/obo/CL_0000981) EquivalentTo [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) + +- [double negative memory B cell](http://purl.obolibrary.org/obo/CL_0000981) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963) + +#### Added +- [double negative memory B cell](http://purl.obolibrary.org/obo/CL_0000981) EquivalentTo [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) + +- [double negative memory B cell](http://purl.obolibrary.org/obo/CL_0000981) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963) + + +### double negative thymocyte `http://purl.obolibrary.org/obo/CL_0002489` +#### Removed +- [double negative thymocyte](http://purl.obolibrary.org/obo/CL_0002489) EquivalentTo [thymocyte](http://purl.obolibrary.org/obo/CL_0000893) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) + +- [double negative thymocyte](http://purl.obolibrary.org/obo/CL_0002489) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [double negative thymocyte](http://purl.obolibrary.org/obo/CL_0002489) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402) + +#### Added +- [double negative thymocyte](http://purl.obolibrary.org/obo/CL_0002489) EquivalentTo [thymocyte](http://purl.obolibrary.org/obo/CL_0000893) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) + +- [double negative thymocyte](http://purl.obolibrary.org/obo/CL_0002489) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [double negative thymocyte](http://purl.obolibrary.org/obo/CL_0002489) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402) + + +### drug `http://purl.obolibrary.org/obo/CHEBI_23888` +#### Removed +- [drug](http://purl.obolibrary.org/obo/CHEBI_23888) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "medicine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [drug](http://purl.obolibrary.org/obo/CHEBI_23888) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [drug](http://purl.obolibrary.org/obo/CHEBI_23888) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [drug](http://purl.obolibrary.org/obo/CHEBI_23888) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [drug](http://purl.obolibrary.org/obo/CHEBI_23888) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances." + +- [drug](http://purl.obolibrary.org/obo/CHEBI_23888) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:23888" + +- [drug](http://purl.obolibrary.org/obo/CHEBI_23888) [label](http://www.w3.org/2000/01/rdf-schema#label) "drug" + +- Class: [drug](http://purl.obolibrary.org/obo/CHEBI_23888) + +- [drug](http://purl.obolibrary.org/obo/CHEBI_23888) SubClassOf [pharmaceutical](http://purl.obolibrary.org/obo/CHEBI_52217) + + + +### early T lineage precursor `http://purl.obolibrary.org/obo/CL_0002425` +#### Removed +- [early T lineage precursor](http://purl.obolibrary.org/obo/CL_0002425) EquivalentTo [pro-T cell](http://purl.obolibrary.org/obo/CL_0000827) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) + +- [early T lineage precursor](http://purl.obolibrary.org/obo/CL_0002425) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + +#### Added +- [early T lineage precursor](http://purl.obolibrary.org/obo/CL_0002425) EquivalentTo [pro-T cell](http://purl.obolibrary.org/obo/CL_0000827) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) + +- [early T lineage precursor](http://purl.obolibrary.org/obo/CL_0002425) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + + +### early lymphoid progenitor `http://purl.obolibrary.org/obo/CL_0000936` +#### Removed +- [early lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0000936) EquivalentTo [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [lymphocyte differentiation](http://purl.obolibrary.org/obo/GO_0030098)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [glycophorin-A](http://purl.obolibrary.org/obo/PR_000001460)) + +- [early lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0000936) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [glycophorin-A](http://purl.obolibrary.org/obo/PR_000001460) + +- [early lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0000936) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + +#### Added +- [early lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0000936) EquivalentTo [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [glycophorin-A](http://purl.obolibrary.org/obo/PR_000001460)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [lymphocyte differentiation](http://purl.obolibrary.org/obo/GO_0030098)) + +- [early lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0000936) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [glycophorin-A](http://purl.obolibrary.org/obo/PR_000001460) + + +### early pro-B cell `http://purl.obolibrary.org/obo/CL_0002046` +#### Removed +- [early pro-B cell](http://purl.obolibrary.org/obo/CL_0002046) EquivalentTo [pro-B cell](http://purl.obolibrary.org/obo/CL_0000826) and ([participates in](http://purl.obolibrary.org/obo/RO_0000056) some [immunoglobulin heavy chain V-D-J recombination](http://purl.obolibrary.org/obo/GO_0071707)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [pre-B cell receptor complex](http://purl.obolibrary.org/obo/GO_0035369)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [B-cell receptor CD22](http://purl.obolibrary.org/obo/PR_000001288)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [neprilysin](http://purl.obolibrary.org/obo/PR_000001898)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338)) + +- [early pro-B cell](http://purl.obolibrary.org/obo/CL_0002046) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338) + +- [early pro-B cell](http://purl.obolibrary.org/obo/CL_0002046) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [early pro-B cell](http://purl.obolibrary.org/obo/CL_0002046) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +#### Added +- [early pro-B cell](http://purl.obolibrary.org/obo/CL_0002046) EquivalentTo [pro-B cell](http://purl.obolibrary.org/obo/CL_0000826) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338)) and ([participates in](http://purl.obolibrary.org/obo/RO_0000056) some [immunoglobulin heavy chain V-D-J recombination](http://purl.obolibrary.org/obo/GO_0071707)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [pre-B cell receptor complex](http://purl.obolibrary.org/obo/GO_0035369)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [B-cell receptor CD22](http://purl.obolibrary.org/obo/PR_000001288)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [neprilysin](http://purl.obolibrary.org/obo/PR_000001898)) + +- [early pro-B cell](http://purl.obolibrary.org/obo/CL_0002046) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338) + +- [early pro-B cell](http://purl.obolibrary.org/obo/CL_0002046) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [early pro-B cell](http://purl.obolibrary.org/obo/CL_0002046) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + + +### ecdysteroid `http://purl.obolibrary.org/obo/CHEBI_23897` +#### Removed +- [ecdysteroid](http://purl.obolibrary.org/obo/CHEBI_23897) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ecdysteroid" + +- [ecdysteroid](http://purl.obolibrary.org/obo/CHEBI_23897) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23896" + +- [ecdysteroid](http://purl.obolibrary.org/obo/CHEBI_23897) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ecdysteroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ecdysteroid](http://purl.obolibrary.org/obo/CHEBI_23897) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [ecdysteroid](http://purl.obolibrary.org/obo/CHEBI_23897) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ecdysteroid hormones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ecdysteroid](http://purl.obolibrary.org/obo/CHEBI_23897) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:23897" + +- [ecdysteroid](http://purl.obolibrary.org/obo/CHEBI_23897) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [ecdysteroid](http://purl.obolibrary.org/obo/CHEBI_23897) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A class of steroids that include insect moulting and sex hormones." + +- [ecdysteroid](http://purl.obolibrary.org/obo/CHEBI_23897) [label](http://www.w3.org/2000/01/rdf-schema#label) "ecdysteroid" + +- [ecdysteroid](http://purl.obolibrary.org/obo/CHEBI_23897) SubClassOf [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) + +- [ecdysteroid](http://purl.obolibrary.org/obo/CHEBI_23897) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [hormone](http://purl.obolibrary.org/obo/CHEBI_24621) + + + +### ecdysteroid biosynthetic process `http://purl.obolibrary.org/obo/GO_0045456` +#### Removed +- [ecdysteroid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045456) SubClassOf [steroid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006694) + + + +### ecdysteroid catabolic process `http://purl.obolibrary.org/obo/GO_0046344` +#### Removed +- [ecdysteroid catabolic process](http://purl.obolibrary.org/obo/GO_0046344) SubClassOf [steroid catabolic process](http://purl.obolibrary.org/obo/GO_0006706) + + + +### ecdysteroid metabolic process `http://purl.obolibrary.org/obo/GO_0045455` +#### Removed +- [ecdysteroid metabolic process](http://purl.obolibrary.org/obo/GO_0045455) SubClassOf [steroid metabolic process](http://purl.obolibrary.org/obo/GO_0008202) + + + +### ecto-epithelial cell of viscerocranial mucosa `http://purl.obolibrary.org/obo/CL_0002283` +#### Removed +- [ecto-epithelial cell of viscerocranial mucosa](http://purl.obolibrary.org/obo/CL_0002283) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000440" + + + +### ectodermal cell `http://purl.obolibrary.org/obo/CL_0000221` +#### Removed +- [ectodermal cell](http://purl.obolibrary.org/obo/CL_0000221) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### effector CD4-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0001044` +#### Removed +- [effector CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001044) EquivalentTo [effector T cell](http://purl.obolibrary.org/obo/CL_0000911) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-beta T cell receptor complex](http://purl.obolibrary.org/obo/GO_0042105)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) + +- [effector CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001044) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203) + +#### Added +- [effector CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001044) EquivalentTo [effector T cell](http://purl.obolibrary.org/obo/CL_0000911) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-beta T cell receptor complex](http://purl.obolibrary.org/obo/GO_0042105)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) + +- [effector CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001044) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203) + + +### effector CD8-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0001050` +#### Removed +- [effector CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001050) EquivalentTo [effector T cell](http://purl.obolibrary.org/obo/CL_0000911) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-beta T cell receptor complex](http://purl.obolibrary.org/obo/GO_0042105)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) + +- [effector CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001050) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203) + +#### Added +- [effector CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001050) EquivalentTo [effector T cell](http://purl.obolibrary.org/obo/CL_0000911) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-beta T cell receptor complex](http://purl.obolibrary.org/obo/GO_0042105)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) + +- [effector CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001050) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203) + + +### effector memory CD4-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000905` +#### Removed +- [effector memory CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000905) EquivalentTo [CD4-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001204) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) + +- [effector memory CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000905) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + +- [effector memory CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000905) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203) + +#### Added +- [effector memory CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000905) EquivalentTo [CD4-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001204) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) + +- [effector memory CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000905) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203) + +- [effector memory CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000905) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + + +### effector memory CD4-positive, alpha-beta T cell, terminally differentiated `http://purl.obolibrary.org/obo/CL_0001087` +#### Removed +- [effector memory CD4-positive, alpha-beta T cell, terminally differentiated](http://purl.obolibrary.org/obo/CL_0001087) EquivalentTo [CD4-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000897) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) + +- [effector memory CD4-positive, alpha-beta T cell, terminally differentiated](http://purl.obolibrary.org/obo/CL_0001087) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203) + +- [effector memory CD4-positive, alpha-beta T cell, terminally differentiated](http://purl.obolibrary.org/obo/CL_0001087) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017) + +#### Added +- [effector memory CD4-positive, alpha-beta T cell, terminally differentiated](http://purl.obolibrary.org/obo/CL_0001087) EquivalentTo [CD4-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000897) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) + +- [effector memory CD4-positive, alpha-beta T cell, terminally differentiated](http://purl.obolibrary.org/obo/CL_0001087) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203) + +- [effector memory CD4-positive, alpha-beta T cell, terminally differentiated](http://purl.obolibrary.org/obo/CL_0001087) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017) + + +### effector memory CD8-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000913` +#### Removed +- [effector memory CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000913) EquivalentTo [CD8-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001203) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) + +- [effector memory CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000913) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203) + +- [effector memory CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000913) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + +#### Added +- [effector memory CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000913) EquivalentTo [CD8-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001203) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) + +- [effector memory CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000913) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) + +- [effector memory CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000913) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203) + + +### effector memory CD8-positive, alpha-beta T cell, terminally differentiated `http://purl.obolibrary.org/obo/CL_0001062` +#### Removed +- [effector memory CD8-positive, alpha-beta T cell, terminally differentiated](http://purl.obolibrary.org/obo/CL_0001062) EquivalentTo [CD8-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000909) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) + +- [effector memory CD8-positive, alpha-beta T cell, terminally differentiated](http://purl.obolibrary.org/obo/CL_0001062) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017) + +- [effector memory CD8-positive, alpha-beta T cell, terminally differentiated](http://purl.obolibrary.org/obo/CL_0001062) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203) + +#### Added +- [effector memory CD8-positive, alpha-beta T cell, terminally differentiated](http://purl.obolibrary.org/obo/CL_0001062) EquivalentTo [CD8-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000909) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) + +- [effector memory CD8-positive, alpha-beta T cell, terminally differentiated](http://purl.obolibrary.org/obo/CL_0001062) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203) + +- [effector memory CD8-positive, alpha-beta T cell, terminally differentiated](http://purl.obolibrary.org/obo/CL_0001062) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017) + + +### egg follicle `http://purl.obolibrary.org/obo/UBERON_8450001` +#### Removed +- [egg follicle](http://purl.obolibrary.org/obo/UBERON_8450001) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-6095-8718](http://orcid.org/0000-0002-6095-8718) + +#### Added +- [egg follicle](http://purl.obolibrary.org/obo/UBERON_8450001) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-6095-8718](https://orcid.org/0000-0002-6095-8718) + + +### electron `http://purl.obolibrary.org/obo/CHEBI_10545` +#### Removed +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "beta" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C05359" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "e" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:10545" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "0.0" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV." + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21614077" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "e-" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Elektron" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "e(-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "electron" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "electron" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "negatron" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "beta-particle" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [label](http://www.w3.org/2000/01/rdf-schema#label) "electron" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "beta(-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Electron" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "electron" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) [mass](http://purl.obolibrary.org/obo/chebi/mass) "0.000548579903" + +- Class: [electron](http://purl.obolibrary.org/obo/CHEBI_10545) + +- [electron](http://purl.obolibrary.org/obo/CHEBI_10545) SubClassOf [lepton](http://purl.obolibrary.org/obo/CHEBI_36338) + + + +### elemental calcium `http://purl.obolibrary.org/obo/CHEBI_35155` +#### Removed +- [elemental calcium](http://purl.obolibrary.org/obo/CHEBI_35155) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35155" + +- [elemental calcium](http://purl.obolibrary.org/obo/CHEBI_35155) [label](http://www.w3.org/2000/01/rdf-schema#label) "elemental calcium" + +- [elemental calcium](http://purl.obolibrary.org/obo/CHEBI_35155) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [elemental calcium](http://purl.obolibrary.org/obo/CHEBI_35155) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [elemental calcium](http://purl.obolibrary.org/obo/CHEBI_35155) + +- [elemental calcium](http://purl.obolibrary.org/obo/CHEBI_35155) SubClassOf [calcium molecular entity](http://purl.obolibrary.org/obo/CHEBI_22985) + + + +### elemental iron `http://purl.obolibrary.org/obo/CHEBI_82663` +#### Removed +- [elemental iron](http://purl.obolibrary.org/obo/CHEBI_82663) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An elemental molecular entity in which all of the atoms have atomic number 26." + +- [elemental iron](http://purl.obolibrary.org/obo/CHEBI_82663) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:82663" + +- [elemental iron](http://purl.obolibrary.org/obo/CHEBI_82663) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [elemental iron](http://purl.obolibrary.org/obo/CHEBI_82663) [label](http://www.w3.org/2000/01/rdf-schema#label) "elemental iron" + +- [elemental iron](http://purl.obolibrary.org/obo/CHEBI_82663) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [elemental iron](http://purl.obolibrary.org/obo/CHEBI_82663) + +- [elemental iron](http://purl.obolibrary.org/obo/CHEBI_82663) SubClassOf [elemental molecular entity](http://purl.obolibrary.org/obo/CHEBI_33259) + +- [elemental iron](http://purl.obolibrary.org/obo/CHEBI_82663) SubClassOf [iron molecular entity](http://purl.obolibrary.org/obo/CHEBI_24873) + + + +### elemental molecular entity `http://purl.obolibrary.org/obo/CHEBI_33259` +#### Removed +- [elemental molecular entity](http://purl.obolibrary.org/obo/CHEBI_33259) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "homoatomic molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [elemental molecular entity](http://purl.obolibrary.org/obo/CHEBI_33259) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "homoatomic entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [elemental molecular entity](http://purl.obolibrary.org/obo/CHEBI_33259) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [elemental molecular entity](http://purl.obolibrary.org/obo/CHEBI_33259) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [elemental molecular entity](http://purl.obolibrary.org/obo/CHEBI_33259) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "homoatomic molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [elemental molecular entity](http://purl.obolibrary.org/obo/CHEBI_33259) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33259" + +- [elemental molecular entity](http://purl.obolibrary.org/obo/CHEBI_33259) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecular entity all atoms of which have the same atomic number." + +- [elemental molecular entity](http://purl.obolibrary.org/obo/CHEBI_33259) [label](http://www.w3.org/2000/01/rdf-schema#label) "elemental molecular entity" + +- Class: [elemental molecular entity](http://purl.obolibrary.org/obo/CHEBI_33259) + +- [elemental molecular entity](http://purl.obolibrary.org/obo/CHEBI_33259) SubClassOf [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) + + + +### elemental molecule `http://purl.obolibrary.org/obo/CHEBI_25362` +#### Removed +- [elemental molecule](http://purl.obolibrary.org/obo/CHEBI_25362) [label](http://www.w3.org/2000/01/rdf-schema#label) "elemental molecule" + +- [elemental molecule](http://purl.obolibrary.org/obo/CHEBI_25362) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [elemental molecule](http://purl.obolibrary.org/obo/CHEBI_25362) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25362" + +- [elemental molecule](http://purl.obolibrary.org/obo/CHEBI_25362) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [elemental molecule](http://purl.obolibrary.org/obo/CHEBI_25362) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecule all atoms of which have the same atomic number." + +- [elemental molecule](http://purl.obolibrary.org/obo/CHEBI_25362) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "homoatomic molecules" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [elemental molecule](http://purl.obolibrary.org/obo/CHEBI_25362) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "homoatomic molecule" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [elemental molecule](http://purl.obolibrary.org/obo/CHEBI_25362) + +- [elemental molecule](http://purl.obolibrary.org/obo/CHEBI_25362) SubClassOf [elemental molecular entity](http://purl.obolibrary.org/obo/CHEBI_33259) + +- [elemental molecule](http://purl.obolibrary.org/obo/CHEBI_25362) SubClassOf [molecule](http://purl.obolibrary.org/obo/CHEBI_25367) + + + +### elemental oxygen `http://purl.obolibrary.org/obo/CHEBI_33262` +#### Removed +- [elemental oxygen](http://purl.obolibrary.org/obo/CHEBI_33262) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [elemental oxygen](http://purl.obolibrary.org/obo/CHEBI_33262) [label](http://www.w3.org/2000/01/rdf-schema#label) "elemental oxygen" + +- [elemental oxygen](http://purl.obolibrary.org/obo/CHEBI_33262) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33262" + +- [elemental oxygen](http://purl.obolibrary.org/obo/CHEBI_33262) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [elemental oxygen](http://purl.obolibrary.org/obo/CHEBI_33262) + +- [elemental oxygen](http://purl.obolibrary.org/obo/CHEBI_33262) SubClassOf [oxygen molecular entity](http://purl.obolibrary.org/obo/CHEBI_25806) + +- [elemental oxygen](http://purl.obolibrary.org/obo/CHEBI_33262) SubClassOf [elemental molecular entity](http://purl.obolibrary.org/obo/CHEBI_33259) + +- [elemental oxygen](http://purl.obolibrary.org/obo/CHEBI_33262) SubClassOf [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) + + + +### elemental sodium `http://purl.obolibrary.org/obo/CHEBI_37246` +#### Removed +- [elemental sodium](http://purl.obolibrary.org/obo/CHEBI_37246) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [elemental sodium](http://purl.obolibrary.org/obo/CHEBI_37246) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [elemental sodium](http://purl.obolibrary.org/obo/CHEBI_37246) [label](http://www.w3.org/2000/01/rdf-schema#label) "elemental sodium" + +- [elemental sodium](http://purl.obolibrary.org/obo/CHEBI_37246) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:37246" + +- Class: [elemental sodium](http://purl.obolibrary.org/obo/CHEBI_37246) + +- [elemental sodium](http://purl.obolibrary.org/obo/CHEBI_37246) SubClassOf [sodium molecular entity](http://purl.obolibrary.org/obo/CHEBI_26712) + + + +### enabled by `http://purl.obolibrary.org/obo/RO_0002333` +#### Removed +- [enabled by](http://purl.obolibrary.org/obo/RO_0002333) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [enabled by](http://purl.obolibrary.org/obo/RO_0002333) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### enables `http://purl.obolibrary.org/obo/RO_0002327` +#### Removed +- [enables](http://purl.obolibrary.org/obo/RO_0002327) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [enables](http://purl.obolibrary.org/obo/RO_0002327) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### enables subfunction `http://purl.obolibrary.org/obo/RO_0004031` +#### Removed +- [enables subfunction](http://purl.obolibrary.org/obo/RO_0004031) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "cjm" + +#### Added +- [enables subfunction](http://purl.obolibrary.org/obo/RO_0004031) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### endocardial cell `http://purl.obolibrary.org/obo/CL_0002350` +#### Removed +- [endocardial cell](http://purl.obolibrary.org/obo/CL_0002350) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000475" + + + +### endocrine cell `http://purl.obolibrary.org/obo/CL_0000163` +#### Removed +- [endocrine cell](http://purl.obolibrary.org/obo/CL_0000163) EquivalentTo [secretory cell](http://purl.obolibrary.org/obo/CL_0000151) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [endocrine hormone secretion](http://purl.obolibrary.org/obo/GO_0060986)) + +- [endocrine cell](http://purl.obolibrary.org/obo/CL_0000163) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [endocrine gland](http://purl.obolibrary.org/obo/UBERON_0002368) + +- [endocrine cell](http://purl.obolibrary.org/obo/CL_0000163) SubClassOf [capable of](http://purl.obolibrary.org/obo/RO_0002215) some [endocrine hormone secretion](http://purl.obolibrary.org/obo/GO_0060986) + +#### Added +- [endocrine cell](http://purl.obolibrary.org/obo/CL_0000163) EquivalentTo [native cell](http://purl.obolibrary.org/obo/CL_0000003) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some +([hormone secretion](http://purl.obolibrary.org/obo/GO_0046879) and ([has target end location](http://purl.obolibrary.org/obo/RO_0002339) some [circulatory system](http://purl.obolibrary.org/obo/UBERON_0001009)))) + +- [endocrine cell](http://purl.obolibrary.org/obo/CL_0000163) SubClassOf [capable of](http://purl.obolibrary.org/obo/RO_0002215) some +([hormone secretion](http://purl.obolibrary.org/obo/GO_0046879) and ([has target end location](http://purl.obolibrary.org/obo/RO_0002339) some [circulatory system](http://purl.obolibrary.org/obo/UBERON_0001009))) + +- [endocrine cell](http://purl.obolibrary.org/obo/CL_0000163) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [endocrine system](http://purl.obolibrary.org/obo/UBERON_0000949) + + +### endocytosis `http://purl.obolibrary.org/obo/GO_0006897` +#### Removed +- [endocytosis](http://purl.obolibrary.org/obo/GO_0006897) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0716731363" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +#### Added +- [endocytosis](http://purl.obolibrary.org/obo/GO_0006897) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24907"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [endocytosis](http://purl.obolibrary.org/obo/GO_0006897) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0716731363" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Endocytosis" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + + +### endodermal cell `http://purl.obolibrary.org/obo/CL_0000223` +#### Removed +- [endodermal cell](http://purl.obolibrary.org/obo/CL_0000223) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### endothelial cell of artery `http://purl.obolibrary.org/obo/CL_1000413` +#### Removed +- [endothelial cell of artery](http://purl.obolibrary.org/obo/CL_1000413) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0002542" + + + +### endothelial cell of lymphatic vessel `http://purl.obolibrary.org/obo/CL_0002138` +#### Removed +- [endothelial cell of lymphatic vessel](http://purl.obolibrary.org/obo/CL_0002138) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000421" + + + +### endothelial cell of sinusoid `http://purl.obolibrary.org/obo/CL_0002262` +#### Removed +- [endothelial cell of sinusoid](http://purl.obolibrary.org/obo/CL_0002262) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000403" + + + +### endothelial cell of viscerocranial mucosa `http://purl.obolibrary.org/obo/CL_0002261` +#### Removed +- [endothelial cell of viscerocranial mucosa](http://purl.obolibrary.org/obo/CL_0002261) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000446" + + + +### endothelium of arteriole `http://purl.obolibrary.org/obo/UBERON_0001916` + +#### Added +- [endothelium of arteriole](http://purl.obolibrary.org/obo/UBERON_0001916) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + +- [endothelium of arteriole](http://purl.obolibrary.org/obo/UBERON_0001916) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + + +### ends `http://purl.obolibrary.org/obo/RO_0002229` + +#### Added +- [ends](http://purl.obolibrary.org/obo/RO_0002229) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### ends with `http://purl.obolibrary.org/obo/RO_0002230` + +#### Added +- [ends with](http://purl.obolibrary.org/obo/RO_0002230) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### enone `http://purl.obolibrary.org/obo/CHEBI_51689` +#### Removed +- [enone](http://purl.obolibrary.org/obo/CHEBI_51689) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Enone" + +- [enone](http://purl.obolibrary.org/obo/CHEBI_51689) [label](http://www.w3.org/2000/01/rdf-schema#label) "enone" + +- [enone](http://purl.obolibrary.org/obo/CHEBI_51689) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [enone](http://purl.obolibrary.org/obo/CHEBI_51689) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[*]\C([*])=C(\[*])C([*])=O" + +- [enone](http://purl.obolibrary.org/obo/CHEBI_51689) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An alpha,beta-unsaturated ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) in which the C=O function is conjugated to a C=C double bond at the alpha,beta position." + +- [enone](http://purl.obolibrary.org/obo/CHEBI_51689) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "51.99491" + +- [enone](http://purl.obolibrary.org/obo/CHEBI_51689) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [enone](http://purl.obolibrary.org/obo/CHEBI_51689) [mass](http://purl.obolibrary.org/obo/chebi/mass) "52.03150" + +- [enone](http://purl.obolibrary.org/obo/CHEBI_51689) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C3OR4" + +- [enone](http://purl.obolibrary.org/obo/CHEBI_51689) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:51689" + +- [enone](http://purl.obolibrary.org/obo/CHEBI_51689) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [enone](http://purl.obolibrary.org/obo/CHEBI_51689) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "enones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [enone](http://purl.obolibrary.org/obo/CHEBI_51689) + +- [enone](http://purl.obolibrary.org/obo/CHEBI_51689) SubClassOf [olefinic compound](http://purl.obolibrary.org/obo/CHEBI_78840) + +- [enone](http://purl.obolibrary.org/obo/CHEBI_51689) SubClassOf [alpha,beta-unsaturated ketone](http://purl.obolibrary.org/obo/CHEBI_51721) + + + +### enterocyte of epithelium proper of large intestine `http://purl.obolibrary.org/obo/CL_1000346` +#### Removed +- [enterocyte of epithelium proper of large intestine](http://purl.obolibrary.org/obo/CL_1000346) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000336" + + + +### enzyme inhibitor `http://purl.obolibrary.org/obo/CHEBI_23924` +#### Removed +- [enzyme inhibitor](http://purl.obolibrary.org/obo/CHEBI_23924) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inhibidor enzimatico" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [enzyme inhibitor](http://purl.obolibrary.org/obo/CHEBI_23924) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [enzyme inhibitor](http://purl.obolibrary.org/obo/CHEBI_23924) [label](http://www.w3.org/2000/01/rdf-schema#label) "enzyme inhibitor" + +- [enzyme inhibitor](http://purl.obolibrary.org/obo/CHEBI_23924) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [enzyme inhibitor](http://purl.obolibrary.org/obo/CHEBI_23924) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "enzyme inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [enzyme inhibitor](http://purl.obolibrary.org/obo/CHEBI_23924) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction." + +- [enzyme inhibitor](http://purl.obolibrary.org/obo/CHEBI_23924) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "enzyme inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [enzyme inhibitor](http://purl.obolibrary.org/obo/CHEBI_23924) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:23924" + +- [enzyme inhibitor](http://purl.obolibrary.org/obo/CHEBI_23924) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inhibiteur enzymatique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [enzyme inhibitor](http://purl.obolibrary.org/obo/CHEBI_23924) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inhibidores enzimaticos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [enzyme inhibitor](http://purl.obolibrary.org/obo/CHEBI_23924) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inhibiteurs enzymatiques" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [enzyme inhibitor](http://purl.obolibrary.org/obo/CHEBI_23924) + +- [enzyme inhibitor](http://purl.obolibrary.org/obo/CHEBI_23924) SubClassOf [inhibitor](http://purl.obolibrary.org/obo/CHEBI_35222) + +- [enzyme inhibitor](http://purl.obolibrary.org/obo/CHEBI_23924) SubClassOf [biochemical role](http://purl.obolibrary.org/obo/CHEBI_52206) + + + +### enzyme regulator activity `http://purl.obolibrary.org/obo/GO_0030234` +#### Removed +- [enzyme regulator activity](http://purl.obolibrary.org/obo/GO_0030234) EquivalentTo [molecular function regulator activity](http://purl.obolibrary.org/obo/GO_0098772) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [catalytic activity](http://purl.obolibrary.org/obo/GO_0003824)) + +- [enzyme regulator activity](http://purl.obolibrary.org/obo/GO_0030234) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [catalytic activity](http://purl.obolibrary.org/obo/GO_0003824) + +#### Added +- [enzyme regulator activity](http://purl.obolibrary.org/obo/GO_0030234) EquivalentTo [molecular function regulator activity](http://purl.obolibrary.org/obo/GO_0098772) and ([directly regulates](http://purl.obolibrary.org/obo/RO_0002578) some [catalytic activity](http://purl.obolibrary.org/obo/GO_0003824)) + +- [enzyme regulator activity](http://purl.obolibrary.org/obo/GO_0030234) SubClassOf [directly regulates](http://purl.obolibrary.org/obo/RO_0002578) some [catalytic activity](http://purl.obolibrary.org/obo/GO_0003824) + + +### eosinophil progenitor cell `http://purl.obolibrary.org/obo/CL_0000611` +#### Removed +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) EquivalentTo [granulocytopoietic cell](http://purl.obolibrary.org/obo/CL_0002191) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [transcription factor PU.1](http://purl.obolibrary.org/obo/PR_000001944)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [erythroid transcription factor](http://purl.obolibrary.org/obo/PR_000007857)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-5 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001867)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [eosinophil differentiation](http://purl.obolibrary.org/obo/GO_0030222)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +#### Added +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) EquivalentTo [granulocytopoietic cell](http://purl.obolibrary.org/obo/CL_0002191) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [transcription factor PU.1](http://purl.obolibrary.org/obo/PR_000001944)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [erythroid transcription factor](http://purl.obolibrary.org/obo/PR_000007857)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-5 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001867)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [eosinophil differentiation](http://purl.obolibrary.org/obo/GO_0030222)) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [eosinophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000611) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + + +### eosinophilic myelocyte `http://purl.obolibrary.org/obo/CL_0000612` +#### Removed +- [eosinophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000612) EquivalentTo [immature eosinophil](http://purl.obolibrary.org/obo/CL_0000772) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-(1,3)-fucosyltransferase 4](http://purl.obolibrary.org/obo/PR_000001456)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD33 molecule](http://purl.obolibrary.org/obo/PR_000001892)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [aminopeptidase N](http://purl.obolibrary.org/obo/PR_000002031)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [tertiary granule](http://purl.obolibrary.org/obo/GO_0070820)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) + +- [eosinophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000612) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [tertiary granule](http://purl.obolibrary.org/obo/GO_0070820) + +- [eosinophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000612) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483) + +#### Added +- [eosinophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000612) EquivalentTo [immature eosinophil](http://purl.obolibrary.org/obo/CL_0000772) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582)) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [tertiary granule](http://purl.obolibrary.org/obo/GO_0070820)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-(1,3)-fucosyltransferase 4](http://purl.obolibrary.org/obo/PR_000001456)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD33 molecule](http://purl.obolibrary.org/obo/PR_000001892)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [aminopeptidase N](http://purl.obolibrary.org/obo/PR_000002031)) + +- [eosinophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000612) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483) + +- [eosinophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000612) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [tertiary granule](http://purl.obolibrary.org/obo/GO_0070820) + + +### epidermal cell `http://purl.obolibrary.org/obo/CL_0000362` +#### Removed +- [epidermal cell](http://purl.obolibrary.org/obo/CL_0000362) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000396" + + + +### epidermal ciliary cell `http://purl.obolibrary.org/obo/CL_0007018` +#### Removed +- [epidermal ciliary cell](http://purl.obolibrary.org/obo/CL_0007018) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### epinephrine binding `http://purl.obolibrary.org/obo/GO_0051379` +#### Removed +- [epinephrine binding](http://purl.obolibrary.org/obo/GO_0051379) SubClassOf [catecholamine binding](http://purl.obolibrary.org/obo/GO_1901338) + +#### Added +- [epinephrine binding](http://purl.obolibrary.org/obo/GO_0051379) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### epinephrine biosynthetic process `http://purl.obolibrary.org/obo/GO_0042418` +#### Removed +- [epinephrine biosynthetic process](http://purl.obolibrary.org/obo/GO_0042418) SubClassOf [catecholamine biosynthetic process](http://purl.obolibrary.org/obo/GO_0042423) + +#### Added +- [epinephrine biosynthetic process](http://purl.obolibrary.org/obo/GO_0042418) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### epinephrine catabolic process `http://purl.obolibrary.org/obo/GO_0042419` +#### Removed +- [epinephrine catabolic process](http://purl.obolibrary.org/obo/GO_0042419) SubClassOf [catecholamine catabolic process](http://purl.obolibrary.org/obo/GO_0042424) + +#### Added +- [epinephrine catabolic process](http://purl.obolibrary.org/obo/GO_0042419) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### epinephrine metabolic process `http://purl.obolibrary.org/obo/GO_0042414` +#### Removed +- [epinephrine metabolic process](http://purl.obolibrary.org/obo/GO_0042414) SubClassOf [catecholamine metabolic process](http://purl.obolibrary.org/obo/GO_0006584) + +#### Added +- [epinephrine metabolic process](http://purl.obolibrary.org/obo/GO_0042414) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### epinephrine secretion `http://purl.obolibrary.org/obo/GO_0048242` +#### Removed +- [epinephrine secretion](http://purl.obolibrary.org/obo/GO_0048242) SubClassOf [catecholamine secretion](http://purl.obolibrary.org/obo/GO_0050432) + +#### Added +- [epinephrine secretion](http://purl.obolibrary.org/obo/GO_0048242) SubClassOf [secretion](http://purl.obolibrary.org/obo/GO_0046903) + + +### epinephrine secretion, neurotransmission `http://purl.obolibrary.org/obo/GO_0061529` + +#### Added +- [epinephrine secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061529) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "adrenaline secretion, neurotransmission" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + +- [epinephrine secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061529) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2013-06-21T15:47:22Z" + +- [epinephrine secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061529) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0061529" + +- [epinephrine secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061529) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "dph" + +- [epinephrine secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061529) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The regulated release of epinephrine by a cell in which the epinephrine acts as a neurotransmitter." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + +- [epinephrine secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061529) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [epinephrine secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061529) [label](http://www.w3.org/2000/01/rdf-schema#label) "epinephrine secretion, neurotransmission" + +- Class: [epinephrine secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061529) + +- [epinephrine secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061529) EquivalentTo [neurotransmitter secretion](http://purl.obolibrary.org/obo/GO_0007269) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [adrenaline](http://purl.obolibrary.org/obo/CHEBI_33568)) + +- [epinephrine secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061529) SubClassOf [epinephrine secretion](http://purl.obolibrary.org/obo/GO_0048242) + +- [epinephrine secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061529) SubClassOf [neurotransmitter secretion](http://purl.obolibrary.org/obo/GO_0007269) + + +### epinephrine transport `http://purl.obolibrary.org/obo/GO_0048241` +#### Removed +- [epinephrine transport](http://purl.obolibrary.org/obo/GO_0048241) SubClassOf [catecholamine transport](http://purl.obolibrary.org/obo/GO_0051937) + +#### Added +- [epinephrine transport](http://purl.obolibrary.org/obo/GO_0048241) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### epinephrine uptake `http://purl.obolibrary.org/obo/GO_0051625` +#### Removed +- [epinephrine uptake](http://purl.obolibrary.org/obo/GO_0051625) SubClassOf [catecholamine uptake](http://purl.obolibrary.org/obo/GO_0090493) + +#### Added +- [epinephrine uptake](http://purl.obolibrary.org/obo/GO_0051625) SubClassOf [has target end location](http://purl.obolibrary.org/obo/RO_0002339) some [intracellular anatomical structure](http://purl.obolibrary.org/obo/GO_0005622) + +- [epinephrine uptake](http://purl.obolibrary.org/obo/GO_0051625) SubClassOf [has target start location](http://purl.obolibrary.org/obo/RO_0002338) some [extracellular region](http://purl.obolibrary.org/obo/GO_0005576) + + +### epithelial cell `http://purl.obolibrary.org/obo/CL_0000066` +#### Removed +- [epithelial cell](http://purl.obolibrary.org/obo/CL_0000066) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### epithelial cell of esophagus `http://purl.obolibrary.org/obo/CL_0002252` +#### Removed +- [epithelial cell of esophagus](http://purl.obolibrary.org/obo/CL_0002252) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000402" + + + +### epithelial cell of large intestine `http://purl.obolibrary.org/obo/CL_0002253` +#### Removed +- [epithelial cell of large intestine](http://purl.obolibrary.org/obo/CL_0002253) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000292" + + + +### epithelial cell of parathyroid gland `http://purl.obolibrary.org/obo/CL_0002260` +#### Removed +- [epithelial cell of parathyroid gland](http://purl.obolibrary.org/obo/CL_0002260) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000429" + + + +### epithelial cell of prostate `http://purl.obolibrary.org/obo/CL_0002231` +#### Removed +- [epithelial cell of prostate](http://purl.obolibrary.org/obo/CL_0002231) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000408" + +- [epithelial cell of prostate](http://purl.obolibrary.org/obo/CL_0002231) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000295" + + + +### epithelial cell of prostatic acinus `http://purl.obolibrary.org/obo/CL_0002233` +#### Removed +- [epithelial cell of prostatic acinus](http://purl.obolibrary.org/obo/CL_0002233) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000461" + + + +### epithelial cell of prostatic duct `http://purl.obolibrary.org/obo/CL_0002232` +#### Removed +- [epithelial cell of prostatic duct](http://purl.obolibrary.org/obo/CL_0002232) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000462" + + + +### epithelial cell of small intestine `http://purl.obolibrary.org/obo/CL_0002254` +#### Removed +- [epithelial cell of small intestine](http://purl.obolibrary.org/obo/CL_0002254) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000293" + + + +### epithelial cell of stomach `http://purl.obolibrary.org/obo/CL_0002178` +#### Removed +- [epithelial cell of stomach](http://purl.obolibrary.org/obo/CL_0002178) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000399" + + + +### epithelial cell of thymus `http://purl.obolibrary.org/obo/CL_0002293` +#### Removed +- [epithelial cell of thymus](http://purl.obolibrary.org/obo/CL_0002293) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000459" + + + +### epithelial cell of thyroid gland `http://purl.obolibrary.org/obo/CL_0002257` +#### Removed +- [epithelial cell of thyroid gland](http://purl.obolibrary.org/obo/CL_0002257) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000297" + + + +### epithelial cell of tracheobronchial tree `http://purl.obolibrary.org/obo/CL_0002202` +#### Removed +- [epithelial cell of tracheobronchial tree](http://purl.obolibrary.org/obo/CL_0002202) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000407" + + + +### epithelial cell of uterus `http://purl.obolibrary.org/obo/CL_0002149` +#### Removed +- [epithelial cell of uterus](http://purl.obolibrary.org/obo/CL_0002149) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000294" + + + +### epithelium of lobular bronchiole `http://purl.obolibrary.org/obo/UBERON_8600001` +#### Removed +- [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](http://orcid.org/0000-0001-6677-8489) + +#### Added +- [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + + +### epitope `http://purl.obolibrary.org/obo/CHEBI_53000` +#### Removed +- [epitope](http://purl.obolibrary.org/obo/CHEBI_53000) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "epitope role" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [epitope](http://purl.obolibrary.org/obo/CHEBI_53000) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:53000" + +- [epitope](http://purl.obolibrary.org/obo/CHEBI_53000) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds." + +- [epitope](http://purl.obolibrary.org/obo/CHEBI_53000) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antigenic determinant" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [epitope](http://purl.obolibrary.org/obo/CHEBI_53000) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "epitope function" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [epitope](http://purl.obolibrary.org/obo/CHEBI_53000) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [epitope](http://purl.obolibrary.org/obo/CHEBI_53000) [label](http://www.w3.org/2000/01/rdf-schema#label) "epitope" + +- [epitope](http://purl.obolibrary.org/obo/CHEBI_53000) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [epitope](http://purl.obolibrary.org/obo/CHEBI_53000) + +- [epitope](http://purl.obolibrary.org/obo/CHEBI_53000) SubClassOf [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) + + + +### erythroblast `http://purl.obolibrary.org/obo/CL_0000765` +#### Removed +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) EquivalentTo [erythroid lineage cell](http://purl.obolibrary.org/obo/CL_0000764) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nucleus](http://purl.obolibrary.org/obo/GO_0005634)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [erythrocyte differentiation](http://purl.obolibrary.org/obo/GO_0030218)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [nucleolus](http://purl.obolibrary.org/obo/GO_0005730)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [nucleolus](http://purl.obolibrary.org/obo/GO_0005730) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +#### Added +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) EquivalentTo [erythroid lineage cell](http://purl.obolibrary.org/obo/CL_0000764) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nucleus](http://purl.obolibrary.org/obo/GO_0005634)) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [nucleolus](http://purl.obolibrary.org/obo/GO_0005730)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [erythrocyte differentiation](http://purl.obolibrary.org/obo/GO_0030218)) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [nucleolus](http://purl.obolibrary.org/obo/GO_0005730) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + + +### erythrocyte `http://purl.obolibrary.org/obo/CL_0000232` +#### Removed +- [erythrocyte](http://purl.obolibrary.org/obo/CL_0000232) EquivalentTo [erythroid lineage cell](http://purl.obolibrary.org/obo/CL_0000764) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [biconcave](http://purl.obolibrary.org/obo/PATO_0002039)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [blood circulation](http://purl.obolibrary.org/obo/GO_0008015)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [oxygen transport](http://purl.obolibrary.org/obo/GO_0015671)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [ribosome](http://purl.obolibrary.org/obo/GO_0005840)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) + +- [erythrocyte](http://purl.obolibrary.org/obo/CL_0000232) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [ribosome](http://purl.obolibrary.org/obo/GO_0005840) + +- [erythrocyte](http://purl.obolibrary.org/obo/CL_0000232) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945) + +#### Added +- [erythrocyte](http://purl.obolibrary.org/obo/CL_0000232) EquivalentTo [erythroid lineage cell](http://purl.obolibrary.org/obo/CL_0000764) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [ribosome](http://purl.obolibrary.org/obo/GO_0005840)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [biconcave](http://purl.obolibrary.org/obo/PATO_0002039)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [blood circulation](http://purl.obolibrary.org/obo/GO_0008015)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [oxygen transport](http://purl.obolibrary.org/obo/GO_0015671)) + +- [erythrocyte](http://purl.obolibrary.org/obo/CL_0000232) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945) + +- [erythrocyte](http://purl.obolibrary.org/obo/CL_0000232) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [ribosome](http://purl.obolibrary.org/obo/GO_0005840) + + +### erythroid lineage cell `http://purl.obolibrary.org/obo/CL_0000764` +#### Removed +- [erythroid lineage cell](http://purl.obolibrary.org/obo/CL_0000764) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0002156" + + + +### erythroid progenitor cell, mammalian `http://purl.obolibrary.org/obo/CL_0001066` +#### Removed +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) EquivalentTo [erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0000038) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [erythrocyte differentiation](http://purl.obolibrary.org/obo/GO_0030218)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +#### Added +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) EquivalentTo [erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0000038) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [erythrocyte differentiation](http://purl.obolibrary.org/obo/GO_0030218)) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + + +### ester `http://purl.obolibrary.org/obo/CHEBI_35701` +#### Removed +- [ester](http://purl.obolibrary.org/obo/CHEBI_35701) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35701" + +- [ester](http://purl.obolibrary.org/obo/CHEBI_35701) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Ester" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [ester](http://purl.obolibrary.org/obo/CHEBI_35701) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:4859" + +- [ester](http://purl.obolibrary.org/obo/CHEBI_35701) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ester" + +- [ester](http://purl.obolibrary.org/obo/CHEBI_35701) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [ester](http://purl.obolibrary.org/obo/CHEBI_35701) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Ester" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [ester](http://purl.obolibrary.org/obo/CHEBI_35701) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "esters" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [ester](http://purl.obolibrary.org/obo/CHEBI_35701) [label](http://www.w3.org/2000/01/rdf-schema#label) "ester" + +- [ester](http://purl.obolibrary.org/obo/CHEBI_35701) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00287" + +- [ester](http://purl.obolibrary.org/obo/CHEBI_35701) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23960" + +- [ester](http://purl.obolibrary.org/obo/CHEBI_35701) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "esters" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ester](http://purl.obolibrary.org/obo/CHEBI_35701) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [ester](http://purl.obolibrary.org/obo/CHEBI_35701) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [ester](http://purl.obolibrary.org/obo/CHEBI_35701) + +- [ester](http://purl.obolibrary.org/obo/CHEBI_35701) SubClassOf [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) + + + +### estradiol `http://purl.obolibrary.org/obo/CHEBI_23965` +#### Removed +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17?,18+/m1/s1" + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A 3-hydroxy steroid that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17." + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:42364" + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Estradiol" + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24084694" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [label](http://www.w3.org/2000/01/rdf-schema#label) "estradiol" + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H][C@]12CC[C@]3(C)C(O)CC[C@@]3([H])[C@]1([H])CCc1cc(O)ccc21" + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C18H24O2" + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oestradiol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10696569" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "272.17763" + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "VOXZDWNPVJITMN-WKUFJEKOSA-N" + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:23965" + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [mass](http://purl.obolibrary.org/obo/chebi/mass) "272.38196" + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "estra-1,3,5(10)-triene-3,17-diol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) SubClassOf [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) SubClassOf [17-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36838) + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) SubClassOf [has_parent_hydride](http://purl.obolibrary.org/obo/chebi#has_parent_hydride) some [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) + +- [estradiol](http://purl.obolibrary.org/obo/CHEBI_23965) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + + + +### estradiol binding `http://purl.obolibrary.org/obo/GO_1903924` +#### Removed +- [estradiol binding](http://purl.obolibrary.org/obo/GO_1903924) SubClassOf [steroid binding](http://purl.obolibrary.org/obo/GO_0005496) + +#### Added +- [estradiol binding](http://purl.obolibrary.org/obo/GO_1903924) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### estradiol secretion `http://purl.obolibrary.org/obo/GO_0035938` +#### Removed +- [estradiol secretion](http://purl.obolibrary.org/obo/GO_0035938) SubClassOf [organic hydroxy compound transport](http://purl.obolibrary.org/obo/GO_0015850) + + + +### estrane `http://purl.obolibrary.org/obo/CHEBI_23966` +#### Removed +- [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oestrane" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "JCBN" + +- [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) [label](http://www.w3.org/2000/01/rdf-schema#label) "estrane" + +- [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Oestran" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) [mass](http://purl.obolibrary.org/obo/chebi/mass) "246.43080" + +- [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:3125721" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:23966" + +- [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "estrane" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C18H30/c1-18-11-4-7-17(18)16-9-8-13-5-2-3-6-14(13)15(16)10-12-18/h13-17H,2-12H2,1H3/t13?,14-,15+,16+,17-,18-/m0/s1" + +- [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "246.23475" + +- [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C18H30" + +- [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LIPID_MAPS_instance:LMST02010000" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "LIPID MAPS" + +- [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "GRXPVLPQNMUNNX-MHJRRCNVSA-N" + +- [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H][C@]12CCCCC1CC[C@]1([H])[C@]2([H])CC[C@]2(C)CCC[C@@]12[H]" + +- Class: [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) + +- [estrane](http://purl.obolibrary.org/obo/CHEBI_23966) SubClassOf [steroid fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35508) + + + +### estrogen `http://purl.obolibrary.org/obo/CHEBI_50114` +#### Removed +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Estrogene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oestrogens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Estrogen" + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "estrogene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Oestrogen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oestrogene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Oestrogene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50114" + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "estrogenos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oestrogenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oestrogen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [label](http://www.w3.org/2000/01/rdf-schema#label) "estrogen" + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "estrogenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "estrogeno" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "estrogens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens." + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "estrogenes Hormon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) + +- [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) SubClassOf [sex hormone](http://purl.obolibrary.org/obo/CHEBI_50112) + + + +### estrogen secretion `http://purl.obolibrary.org/obo/GO_0035937` +#### Removed +- [estrogen secretion](http://purl.obolibrary.org/obo/GO_0035937) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [estrogen secretion](http://purl.obolibrary.org/obo/GO_0035937) [label](http://www.w3.org/2000/01/rdf-schema#label) "estrogen secretion" + +- [estrogen secretion](http://purl.obolibrary.org/obo/GO_0035937) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The regulated release of estrogen into the circulatory system. Estrogen is a steroid hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:sl" + +- [estrogen secretion](http://purl.obolibrary.org/obo/GO_0035937) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "bf" + +- [estrogen secretion](http://purl.obolibrary.org/obo/GO_0035937) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-07-20T01:14:44Z" + +- [estrogen secretion](http://purl.obolibrary.org/obo/GO_0035937) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oestrogen secretion" + +- [estrogen secretion](http://purl.obolibrary.org/obo/GO_0035937) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0035937" + +- Class: [estrogen secretion](http://purl.obolibrary.org/obo/GO_0035937) + +- [estrogen secretion](http://purl.obolibrary.org/obo/GO_0035937) EquivalentTo [secretion](http://purl.obolibrary.org/obo/GO_0046903) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114)) + +- [estrogen secretion](http://purl.obolibrary.org/obo/GO_0035937) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [estrogen](http://purl.obolibrary.org/obo/CHEBI_50114) + +- [estrogen secretion](http://purl.obolibrary.org/obo/GO_0035937) SubClassOf [steroid hormone secretion](http://purl.obolibrary.org/obo/GO_0035929) + + + +### eukaryotic metabolite `http://purl.obolibrary.org/obo/CHEBI_75763` +#### Removed +- [eukaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75763) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "eukaryotic metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [eukaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75763) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [eukaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75763) [label](http://www.w3.org/2000/01/rdf-schema#label) "eukaryotic metabolite" + +- [eukaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75763) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:75763" + +- [eukaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75763) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms." + +- [eukaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75763) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [eukaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75763) + +- [eukaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75763) SubClassOf [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) + + + +### evolutionarily related to `http://purl.obolibrary.org/obo/RO_0002320` +#### Removed +- [evolutionarily related to](http://purl.obolibrary.org/obo/RO_0002320) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [evolutionarily related to](http://purl.obolibrary.org/obo/RO_0002320) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### excitatory amino acid agonist `http://purl.obolibrary.org/obo/CHEBI_50103` +#### Removed +- [excitatory amino acid agonist](http://purl.obolibrary.org/obo/CHEBI_50103) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50103" + +- [excitatory amino acid agonist](http://purl.obolibrary.org/obo/CHEBI_50103) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [excitatory amino acid agonist](http://purl.obolibrary.org/obo/CHEBI_50103) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An agent that binds to and activates excitatory amino acid receptors." + +- [excitatory amino acid agonist](http://purl.obolibrary.org/obo/CHEBI_50103) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "excitatory amino acid receptor agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [excitatory amino acid agonist](http://purl.obolibrary.org/obo/CHEBI_50103) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "excitatory amino acid agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [excitatory amino acid agonist](http://purl.obolibrary.org/obo/CHEBI_50103) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "excitatory amino acid receptor agonist" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [excitatory amino acid agonist](http://purl.obolibrary.org/obo/CHEBI_50103) [label](http://www.w3.org/2000/01/rdf-schema#label) "excitatory amino acid agonist" + +- [excitatory amino acid agonist](http://purl.obolibrary.org/obo/CHEBI_50103) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [excitatory amino acid agonist](http://purl.obolibrary.org/obo/CHEBI_50103) + +- [excitatory amino acid agonist](http://purl.obolibrary.org/obo/CHEBI_50103) SubClassOf [neurotransmitter agent](http://purl.obolibrary.org/obo/CHEBI_35942) + + + +### existence ends during `http://purl.obolibrary.org/obo/RO_0002492` +#### Removed +- [existence ends during](http://purl.obolibrary.org/obo/RO_0002492) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [existence ends during](http://purl.obolibrary.org/obo/RO_0002492) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### existence ends during or before `http://purl.obolibrary.org/obo/RO_0002497` +#### Removed +- [existence ends during or before](http://purl.obolibrary.org/obo/RO_0002497) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [existence ends during or before](http://purl.obolibrary.org/obo/RO_0002497) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### existence ends with `http://purl.obolibrary.org/obo/RO_0002493` +#### Removed +- [existence ends with](http://purl.obolibrary.org/obo/RO_0002493) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [existence ends with](http://purl.obolibrary.org/obo/RO_0002493) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### existence overlaps `http://purl.obolibrary.org/obo/RO_0002490` +#### Removed +- [existence overlaps](http://purl.obolibrary.org/obo/RO_0002490) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [existence overlaps](http://purl.obolibrary.org/obo/RO_0002490) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### existence starts and ends during `http://purl.obolibrary.org/obo/RO_0002491` +#### Removed +- [existence starts and ends during](http://purl.obolibrary.org/obo/RO_0002491) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [existence starts and ends during](http://purl.obolibrary.org/obo/RO_0002491) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### existence starts during `http://purl.obolibrary.org/obo/RO_0002488` +#### Removed +- [existence starts during](http://purl.obolibrary.org/obo/RO_0002488) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [existence starts during](http://purl.obolibrary.org/obo/RO_0002488) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### existence starts during or after `http://purl.obolibrary.org/obo/RO_0002496` +#### Removed +- [existence starts during or after](http://purl.obolibrary.org/obo/RO_0002496) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [existence starts during or after](http://purl.obolibrary.org/obo/RO_0002496) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### existence starts with `http://purl.obolibrary.org/obo/RO_0002489` +#### Removed +- [existence starts with](http://purl.obolibrary.org/obo/RO_0002489) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [existence starts with](http://purl.obolibrary.org/obo/RO_0002489) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### exopolysaccharide `http://purl.obolibrary.org/obo/CHEBI_72813` +#### Removed +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:2688547" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20718297" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20172021" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:1444258" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "extracellular polymeric substances" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "extracellular polymeric substance" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11785425" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Extracellular_polymeric_substance" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "exopolysaccharides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:72813" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20631870" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16075348" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment." + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:Exopolysaccharides" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17440912" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Exopolysaccharide" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19453747" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18097339" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [label](http://www.w3.org/2000/01/rdf-schema#label) "exopolysaccharide" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15738217" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:6354590" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11160795" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- Class: [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) + +- [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) SubClassOf [biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33694) + + + +### expressed in `http://purl.obolibrary.org/obo/RO_0002206` +#### Removed +- [expressed in](http://purl.obolibrary.org/obo/RO_0002206) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall"@en + +#### Added +- [expressed in](http://purl.obolibrary.org/obo/RO_0002206) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### expresses `http://purl.obolibrary.org/obo/RO_0002292` +#### Removed +- [expresses](http://purl.obolibrary.org/obo/RO_0002292) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [expresses](http://purl.obolibrary.org/obo/RO_0002292) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### extraembryonic cell `http://purl.obolibrary.org/obo/CL_0000349` +#### Removed +- [extraembryonic cell](http://purl.obolibrary.org/obo/CL_0000349) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### farnesane `http://purl.obolibrary.org/obo/CHEBI_36756` +#### Removed +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "farnesane" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Patent:US2008098645" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "212.25040" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "CCC(C)CCCC(C)CCCC(C)C" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C15H32/c1-6-14(4)10-8-12-15(5)11-7-9-13(2)3/h13-15H,6-12H2,1-5H3" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36756" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:CPD-8764" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:3891-98-3" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:3891-98-3" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [mass](http://purl.obolibrary.org/obo/chebi/mass) "212.41458" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Patent:US7399323" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C15H32" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:1719672" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [label](http://www.w3.org/2000/01/rdf-schema#label) "farnesane" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:1719672" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "YFHFHLSMISYUAQ-UHFFFAOYSA-N" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LIPID_MAPS_instance:LMPR0103010000" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "LIPID MAPS" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Farnesan" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A sesquiterpene that is dodecane substituted by methyl groups at positions 2, 6 and 10." + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "2,6,10-trimethyldodecane" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- Class: [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) SubClassOf [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189) + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [plant metabolite](http://purl.obolibrary.org/obo/CHEBI_76924) + +- [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) SubClassOf [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) + + + +### farnesane sesquiterpenoid `http://purl.obolibrary.org/obo/CHEBI_36757` +#### Removed +- [farnesane sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_36757) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36757" + +- [farnesane sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_36757) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "farnesane sesquiterpenoid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [farnesane sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_36757) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [farnesane sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_36757) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "farnesane sesquiterpenoids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [farnesane sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_36757) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [farnesane sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_36757) [label](http://www.w3.org/2000/01/rdf-schema#label) "farnesane sesquiterpenoid" + +- Class: [farnesane sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_36757) + +- [farnesane sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_36757) SubClassOf [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658) + +- [farnesane sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_36757) SubClassOf [has_parent_hydride](http://purl.obolibrary.org/obo/chebi#has_parent_hydride) some [farnesane](http://purl.obolibrary.org/obo/CHEBI_36756) + + + +### fasciculates with `http://purl.obolibrary.org/obo/RO_0002101` +#### Removed +- [fasciculates with](http://purl.obolibrary.org/obo/RO_0002101) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland" + +- [fasciculates with](http://purl.obolibrary.org/obo/RO_0002101) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Relation between a neuron and the neuron projection bundle it fasciculates with. FOL: x fasciculates_with y iff: exists some 'neuron ; CL_0000540'(x), some 'neuron projection bundle ; CARO_0001001'(y), some 'neuron projection ; GO_0043005'(np), np part_of x AND np overlaps y AND np aligned_with y" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBC:DOS" + +#### Added +- [fasciculates with](http://purl.obolibrary.org/obo/RO_0002101) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + +- [fasciculates with](http://purl.obolibrary.org/obo/RO_0002101) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Relation between a neuron and the neuron projection bundle it fasciculates with. FOL: x fasciculates_with y iff: exists some 'neuron ; CL_0000540'(x), some 'neuron projection bundle ; CARO_0001001'(y), some 'neuron projection ; GO_0043005'(np), np part_of x AND np overlaps y AND np aligned_with y" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + + +### fat cell `http://purl.obolibrary.org/obo/CL_0000136` +#### Removed +- [fat cell](http://purl.obolibrary.org/obo/CL_0000136) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000450" + + + +### fatty acid `http://purl.obolibrary.org/obo/CHEBI_35366` +#### Removed +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "44.99765" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fatty acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fatty_acid" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "OC([*])=O" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13633" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:14328676" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CHO2R" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Fettsaeuren" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fatty acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acide gras" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00162" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Fettsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:4984" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24024" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acidos grasos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids." + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Fettsaeuren" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Fettsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Fatty acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Fatty acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CHO2R" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [FORMULA](http://purl.obolibrary.org/obo/fbbt#FORMULA) + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "OC([*])=O" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [SMILES](http://purl.obolibrary.org/obo/fbbt#SMILES) + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acidos grasos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [mass](http://purl.obolibrary.org/obo/chebi/mass) "45.01740" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fatty acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acido graso" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acido graso" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:14287444" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acide gras" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:14300208" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acides gras" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus:" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acides gras" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fatty acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35366" + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) [label](http://www.w3.org/2000/01/rdf-schema#label) "fatty acid" + +- Class: [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) SubClassOf [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) + +- [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) SubClassOf [lipid](http://purl.obolibrary.org/obo/CHEBI_18059) + + + +### fatty acid 4:0 `http://purl.obolibrary.org/obo/CHEBI_140601` +#### Removed +- [fatty acid 4:0](http://purl.obolibrary.org/obo/CHEBI_140601) [mass](http://purl.obolibrary.org/obo/chebi/mass) "45.017" + +- [fatty acid 4:0](http://purl.obolibrary.org/obo/CHEBI_140601) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any saturated fatty acid containing 4 carbons." + +- [fatty acid 4:0](http://purl.obolibrary.org/obo/CHEBI_140601) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [fatty acid 4:0](http://purl.obolibrary.org/obo/CHEBI_140601) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [fatty acid 4:0](http://purl.obolibrary.org/obo/CHEBI_140601) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CHO2R" + +- [fatty acid 4:0](http://purl.obolibrary.org/obo/CHEBI_140601) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "44.99765" + +- [fatty acid 4:0](http://purl.obolibrary.org/obo/CHEBI_140601) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "*C(O)=O" + +- [fatty acid 4:0](http://purl.obolibrary.org/obo/CHEBI_140601) [label](http://www.w3.org/2000/01/rdf-schema#label) "fatty acid 4:0" + +- [fatty acid 4:0](http://purl.obolibrary.org/obo/CHEBI_140601) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [fatty acid 4:0](http://purl.obolibrary.org/obo/CHEBI_140601) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:140601" + +- Class: [fatty acid 4:0](http://purl.obolibrary.org/obo/CHEBI_140601) + +- [fatty acid 4:0](http://purl.obolibrary.org/obo/CHEBI_140601) SubClassOf [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) + +- [fatty acid 4:0](http://purl.obolibrary.org/obo/CHEBI_140601) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [fatty acid anion 4:0](http://purl.obolibrary.org/obo/CHEBI_78115) + + + +### fatty acid anion `http://purl.obolibrary.org/obo/CHEBI_28868` +#### Removed +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid." + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a fatty acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C02403" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CO2R" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13634" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anion de l'acide gras" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "43.98983" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [label](http://www.w3.org/2000/01/rdf-schema#label) "fatty acid anion" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18628202" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [mass](http://purl.obolibrary.org/obo/chebi/mass) "44.00950" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:28868" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Fatty acid anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[O-]C([*])=O" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acido graso anionico" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Alkanate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Fettsaeureanion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:4985" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Fettsaeureanionen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24022" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fatty acid anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acidos grasos anionicos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) SubClassOf [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) + +- [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) SubClassOf [lipid](http://purl.obolibrary.org/obo/CHEBI_18059) + + + +### fatty acid anion 4:0 `http://purl.obolibrary.org/obo/CHEBI_78115` +#### Removed +- [fatty acid anion 4:0](http://purl.obolibrary.org/obo/CHEBI_78115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fatty acid 4:0" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [fatty acid anion 4:0](http://purl.obolibrary.org/obo/CHEBI_78115) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:78115" + +- [fatty acid anion 4:0](http://purl.obolibrary.org/obo/CHEBI_78115) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[O-]C([*])=O" + +- [fatty acid anion 4:0](http://purl.obolibrary.org/obo/CHEBI_78115) [label](http://www.w3.org/2000/01/rdf-schema#label) "fatty acid anion 4:0" + +- [fatty acid anion 4:0](http://purl.obolibrary.org/obo/CHEBI_78115) [mass](http://purl.obolibrary.org/obo/chebi/mass) "87.09718" + +- [fatty acid anion 4:0](http://purl.obolibrary.org/obo/CHEBI_78115) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [fatty acid anion 4:0](http://purl.obolibrary.org/obo/CHEBI_78115) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any saturated fatty acid anion containing 4 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." + +- [fatty acid anion 4:0](http://purl.obolibrary.org/obo/CHEBI_78115) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C4H7O2" + +- [fatty acid anion 4:0](http://purl.obolibrary.org/obo/CHEBI_78115) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "87.04460" + +- [fatty acid anion 4:0](http://purl.obolibrary.org/obo/CHEBI_78115) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [fatty acid anion 4:0](http://purl.obolibrary.org/obo/CHEBI_78115) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [fatty acid anion 4:0](http://purl.obolibrary.org/obo/CHEBI_78115) + +- [fatty acid anion 4:0](http://purl.obolibrary.org/obo/CHEBI_78115) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [fatty acid 4:0](http://purl.obolibrary.org/obo/CHEBI_140601) + +- [fatty acid anion 4:0](http://purl.obolibrary.org/obo/CHEBI_78115) SubClassOf [saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58953) + +- [fatty acid anion 4:0](http://purl.obolibrary.org/obo/CHEBI_78115) SubClassOf [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) + + + +### fatty acid binding `http://purl.obolibrary.org/obo/GO_0005504` +#### Removed +- [fatty acid binding](http://purl.obolibrary.org/obo/GO_0005504) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0005504" + +- [fatty acid binding](http://purl.obolibrary.org/obo/GO_0005504) [label](http://www.w3.org/2000/01/rdf-schema#label) "fatty acid binding" + +- [fatty acid binding](http://purl.obolibrary.org/obo/GO_0005504) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [fatty acid binding](http://purl.obolibrary.org/obo/GO_0005504) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to a fatty acid, an aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- Class: [fatty acid binding](http://purl.obolibrary.org/obo/GO_0005504) + +- [fatty acid binding](http://purl.obolibrary.org/obo/GO_0005504) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868)) + +- [fatty acid binding](http://purl.obolibrary.org/obo/GO_0005504) SubClassOf [monocarboxylic acid binding](http://purl.obolibrary.org/obo/GO_0033293) + +- [fatty acid binding](http://purl.obolibrary.org/obo/GO_0005504) SubClassOf [lipid binding](http://purl.obolibrary.org/obo/GO_0008289) + +- [fatty acid binding](http://purl.obolibrary.org/obo/GO_0005504) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) + + + +### fatty acid biosynthetic process `http://purl.obolibrary.org/obo/GO_0006633` +#### Removed +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fatty acid synthesis" + +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006633" + +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:PWY-4381" + +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fatty_acid_synthesis" + +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0000037" + +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:PWY-5156" + +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fatty acid biosynthesis" + +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fatty acid formation" + +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:FASYN-INITIAL-PWY" + +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) [label](http://www.w3.org/2000/01/rdf-schema#label) "fatty acid biosynthetic process" + +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fatty acid anabolism" + +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- Class: [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) + +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868)) + +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) SubClassOf [monocarboxylic acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0072330) + +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) SubClassOf [lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008610) + +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) + +- [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) SubClassOf [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631) + + + +### fatty acid catabolic process `http://purl.obolibrary.org/obo/GO_0009062` +#### Removed +- [fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0009062) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fatty acid catabolism" + +- [fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0009062) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0009062" + +- [fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0009062) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fatty acid breakdown" + +- [fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0009062) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0009062) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fatty_acid_degradation" + +- [fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0009062) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fatty acid degradation" + +- [fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0009062) [label](http://www.w3.org/2000/01/rdf-schema#label) "fatty acid catabolic process" + +- [fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0009062) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0009062) + +- [fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0009062) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868)) + +- [fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0009062) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) + +- [fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0009062) SubClassOf [cellular lipid catabolic process](http://purl.obolibrary.org/obo/GO_0044242) + +- [fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0009062) SubClassOf [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631) + +- [fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0009062) SubClassOf [monocarboxylic acid catabolic process](http://purl.obolibrary.org/obo/GO_0072329) + + + +### fatty acid homeostasis `http://purl.obolibrary.org/obo/GO_0055089` +#### Removed +- [fatty acid homeostasis](http://purl.obolibrary.org/obo/GO_0055089) [label](http://www.w3.org/2000/01/rdf-schema#label) "fatty acid homeostasis" + +- [fatty acid homeostasis](http://purl.obolibrary.org/obo/GO_0055089) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:rl" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:BHF" + +- [fatty acid homeostasis](http://purl.obolibrary.org/obo/GO_0055089) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [fatty acid homeostasis](http://purl.obolibrary.org/obo/GO_0055089) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0055089" + +- Class: [fatty acid homeostasis](http://purl.obolibrary.org/obo/GO_0055089) + +- [fatty acid homeostasis](http://purl.obolibrary.org/obo/GO_0055089) EquivalentTo [chemical homeostasis](http://purl.obolibrary.org/obo/GO_0048878) and ([regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868)) + +- [fatty acid homeostasis](http://purl.obolibrary.org/obo/GO_0055089) SubClassOf [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) + +- [fatty acid homeostasis](http://purl.obolibrary.org/obo/GO_0055089) SubClassOf [lipid homeostasis](http://purl.obolibrary.org/obo/GO_0055088) + + + +### fatty acid metabolic process `http://purl.obolibrary.org/obo/GO_0006631` +#### Removed +- [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fatty_acid_metabolism" + +- [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006631" + +- [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631) [label](http://www.w3.org/2000/01/rdf-schema#label) "fatty acid metabolic process" + +- [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198547684" + +- [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fatty acid metabolism" + +- [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631) + +- [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868)) + +- [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631) SubClassOf [monocarboxylic acid metabolic process](http://purl.obolibrary.org/obo/GO_0032787) + +- [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631) SubClassOf [cellular lipid metabolic process](http://purl.obolibrary.org/obo/GO_0044255) + +- [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) + + + +### fatty acid transmembrane transport `http://purl.obolibrary.org/obo/GO_1902001` +#### Removed +- [fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902001) [label](http://www.w3.org/2000/01/rdf-schema#label) "fatty acid transmembrane transport" + +- [fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902001) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The process in which a fatty acid is transported across a membrane." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9395310" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:rb" + +- [fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902001) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902001) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "pr" + +- [fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902001) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2013-03-21T09:57:00Z" + +- [fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902001) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902001" + +- Class: [fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902001) + +- [fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902001) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([results in transport across](http://purl.obolibrary.org/obo/RO_0002342) some [membrane](http://purl.obolibrary.org/obo/GO_0016020)) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868)) + +- [fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902001) SubClassOf [carboxylic acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1905039) + +- [fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902001) SubClassOf [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908) + + + +### fatty acid transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015245` +#### Removed +- [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of fatty acids from one side of a membrane to the other. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) [label](http://www.w3.org/2000/01/rdf-schema#label) "fatty acid transmembrane transporter activity" + +- [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fatty acyl transporter activity" + +- [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fatty acid transporter activity" + +- [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "peroxisomal fatty acyl transporter" + +- [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-879585" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "SLC27A1,4,6 transport LCFAs from extracellular region to cytosol" + +- [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0015246" + +- [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015245" + +- [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-5627891" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol" + +- [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "fatty-acyl group transporter activity" + +- Class: [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) + +- [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) EquivalentTo [transporter activity](http://purl.obolibrary.org/obo/GO_0005215) and ([results in transport across](http://purl.obolibrary.org/obo/RO_0002342) some [membrane](http://purl.obolibrary.org/obo/GO_0016020)) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868)) + +- [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) SubClassOf [lipid transporter activity](http://purl.obolibrary.org/obo/GO_0005319) + +- [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) + +- [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) SubClassOf [carboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046943) + +- [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908) + + + +### fatty acid transport `http://purl.obolibrary.org/obo/GO_0015908` +#### Removed +- [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015908" + +- [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908) [label](http://www.w3.org/2000/01/rdf-schema#label) "fatty acid transport" + +- Class: [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908) + +- [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868)) + +- [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908) SubClassOf [monocarboxylic acid transport](http://purl.obolibrary.org/obo/GO_0015718) + +- [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908) SubClassOf [lipid transport](http://purl.obolibrary.org/obo/GO_0006869) + +- [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) + + + +### fermentation `http://purl.obolibrary.org/obo/GO_0006113` +#### Removed +- [fermentation](http://purl.obolibrary.org/obo/GO_0006113) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [fermentation](http://purl.obolibrary.org/obo/GO_0006113) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006113" + +- [fermentation](http://purl.obolibrary.org/obo/GO_0006113) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_pir](http://purl.obolibrary.org/obo/go#goslim_pir) + +- [fermentation](http://purl.obolibrary.org/obo/GO_0006113) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fermentation_(biochemistry)" + +- [fermentation](http://purl.obolibrary.org/obo/GO_0006113) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:curators" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0201090910" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:Fermentation" + +- [fermentation](http://purl.obolibrary.org/obo/GO_0006113) [label](http://www.w3.org/2000/01/rdf-schema#label) "fermentation" + +- [fermentation](http://purl.obolibrary.org/obo/GO_0006113) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:FERMENTATION-PWY" + +- Class: [fermentation](http://purl.obolibrary.org/obo/GO_0006113) + +- [fermentation](http://purl.obolibrary.org/obo/GO_0006113) SubClassOf [energy derivation by oxidation of organic compounds](http://purl.obolibrary.org/obo/GO_0015980) + + + +### fermion `http://purl.obolibrary.org/obo/CHEBI_36340` +#### Removed +- [fermion](http://purl.obolibrary.org/obo/CHEBI_36340) [label](http://www.w3.org/2000/01/rdf-schema#label) "fermion" + +- [fermion](http://purl.obolibrary.org/obo/CHEBI_36340) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [fermion](http://purl.obolibrary.org/obo/CHEBI_36340) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36340" + +- [fermion](http://purl.obolibrary.org/obo/CHEBI_36340) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fermions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fermion](http://purl.obolibrary.org/obo/CHEBI_36340) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi." + +- [fermion](http://purl.obolibrary.org/obo/CHEBI_36340) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [fermion](http://purl.obolibrary.org/obo/CHEBI_36340) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fermion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- Class: [fermion](http://purl.obolibrary.org/obo/CHEBI_36340) + +- [fermion](http://purl.obolibrary.org/obo/CHEBI_36340) SubClassOf [subatomic particle](http://purl.obolibrary.org/obo/CHEBI_36342) + + + +### fertilizer `http://purl.obolibrary.org/obo/CHEBI_33287` +#### Removed +- [fertilizer](http://purl.obolibrary.org/obo/CHEBI_33287) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [fertilizer](http://purl.obolibrary.org/obo/CHEBI_33287) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33287" + +- [fertilizer](http://purl.obolibrary.org/obo/CHEBI_33287) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fertiliser" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fertilizer](http://purl.obolibrary.org/obo/CHEBI_33287) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A fertilizer is any substance that is added to soil or water to assist the growth of plants." + +- [fertilizer](http://purl.obolibrary.org/obo/CHEBI_33287) [label](http://www.w3.org/2000/01/rdf-schema#label) "fertilizer" + +- [fertilizer](http://purl.obolibrary.org/obo/CHEBI_33287) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [fertilizer](http://purl.obolibrary.org/obo/CHEBI_33287) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fertilizers" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [fertilizer](http://purl.obolibrary.org/obo/CHEBI_33287) + +- [fertilizer](http://purl.obolibrary.org/obo/CHEBI_33287) SubClassOf [agrochemical](http://purl.obolibrary.org/obo/CHEBI_33286) + + + +### fetal liver hematopoietic progenitor cell `http://purl.obolibrary.org/obo/CL_0002353` +#### Removed +- [fetal liver hematopoietic progenitor cell](http://purl.obolibrary.org/obo/CL_0002353) EquivalentTo [gestational hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002352) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC protein complex](http://purl.obolibrary.org/obo/GO_0042611)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C](http://purl.obolibrary.org/obo/PR_000001006)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD48 molecule](http://purl.obolibrary.org/obo/PR_000001308)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [natural killer cell receptor 2B4](http://purl.obolibrary.org/obo/PR_000001896)) + +- [fetal liver hematopoietic progenitor cell](http://purl.obolibrary.org/obo/CL_0002353) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [natural killer cell receptor 2B4](http://purl.obolibrary.org/obo/PR_000001896) + +- [fetal liver hematopoietic progenitor cell](http://purl.obolibrary.org/obo/CL_0002353) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD48 molecule](http://purl.obolibrary.org/obo/PR_000001308) + +#### Added +- [fetal liver hematopoietic progenitor cell](http://purl.obolibrary.org/obo/CL_0002353) EquivalentTo [gestational hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002352) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD48 molecule](http://purl.obolibrary.org/obo/PR_000001308)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [natural killer cell receptor 2B4](http://purl.obolibrary.org/obo/PR_000001896)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC protein complex](http://purl.obolibrary.org/obo/GO_0042611)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C](http://purl.obolibrary.org/obo/PR_000001006)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) + +- [fetal liver hematopoietic progenitor cell](http://purl.obolibrary.org/obo/CL_0002353) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [natural killer cell receptor 2B4](http://purl.obolibrary.org/obo/PR_000001896) + +- [fetal liver hematopoietic progenitor cell](http://purl.obolibrary.org/obo/CL_0002353) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD48 molecule](http://purl.obolibrary.org/obo/PR_000001308) + + +### fibrocyte `http://purl.obolibrary.org/obo/CL_0000135` +#### Removed +- [fibrocyte](http://purl.obolibrary.org/obo/CL_0000135) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### flask cell `http://purl.obolibrary.org/obo/CL_0007023` +#### Removed +- [flask cell](http://purl.obolibrary.org/obo/CL_0007023) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### follicular B cell `http://purl.obolibrary.org/obo/CL_0000843` +#### Removed +- [follicular B cell](http://purl.obolibrary.org/obo/CL_0000843) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) + +- [follicular B cell](http://purl.obolibrary.org/obo/CL_0000843) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037) + +- [follicular B cell](http://purl.obolibrary.org/obo/CL_0000843) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +#### Added +- [follicular B cell](http://purl.obolibrary.org/obo/CL_0000843) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338)) + +- [follicular B cell](http://purl.obolibrary.org/obo/CL_0000843) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037) + +- [follicular B cell](http://purl.obolibrary.org/obo/CL_0000843) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + + +### follicular fluid `http://purl.obolibrary.org/obo/UBERON_0000038` +#### Removed +- [follicular fluid](http://purl.obolibrary.org/obo/UBERON_0000038) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + + + +### food acidity regulator `http://purl.obolibrary.org/obo/CHEBI_64049` +#### Removed +- [food acidity regulator](http://purl.obolibrary.org/obo/CHEBI_64049) [label](http://www.w3.org/2000/01/rdf-schema#label) "food acidity regulator" + +- [food acidity regulator](http://purl.obolibrary.org/obo/CHEBI_64049) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [food acidity regulator](http://purl.obolibrary.org/obo/CHEBI_64049) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [food acidity regulator](http://purl.obolibrary.org/obo/CHEBI_64049) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents." + +- [food acidity regulator](http://purl.obolibrary.org/obo/CHEBI_64049) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Acidity_regulator" + +- [food acidity regulator](http://purl.obolibrary.org/obo/CHEBI_64049) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acidity regulator" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [food acidity regulator](http://purl.obolibrary.org/obo/CHEBI_64049) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pH control agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [food acidity regulator](http://purl.obolibrary.org/obo/CHEBI_64049) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "food acidity regulators" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [food acidity regulator](http://purl.obolibrary.org/obo/CHEBI_64049) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:64049" + +- [food acidity regulator](http://purl.obolibrary.org/obo/CHEBI_64049) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pH control agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [food acidity regulator](http://purl.obolibrary.org/obo/CHEBI_64049) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acidity regulators" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [food acidity regulator](http://purl.obolibrary.org/obo/CHEBI_64049) + +- [food acidity regulator](http://purl.obolibrary.org/obo/CHEBI_64049) SubClassOf [food additive](http://purl.obolibrary.org/obo/CHEBI_64047) + + + +### food additive `http://purl.obolibrary.org/obo/CHEBI_64047` +#### Removed +- [food additive](http://purl.obolibrary.org/obo/CHEBI_64047) [label](http://www.w3.org/2000/01/rdf-schema#label) "food additive" + +- [food additive](http://purl.obolibrary.org/obo/CHEBI_64047) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any substance which is added to food to preserve or enhance its flavour and/or appearance." + +- [food additive](http://purl.obolibrary.org/obo/CHEBI_64047) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:64047" + +- [food additive](http://purl.obolibrary.org/obo/CHEBI_64047) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Food_additive" + +- [food additive](http://purl.obolibrary.org/obo/CHEBI_64047) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "food additives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [food additive](http://purl.obolibrary.org/obo/CHEBI_64047) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [food additive](http://purl.obolibrary.org/obo/CHEBI_64047) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [food additive](http://purl.obolibrary.org/obo/CHEBI_64047) + +- [food additive](http://purl.obolibrary.org/obo/CHEBI_64047) SubClassOf [application](http://purl.obolibrary.org/obo/CHEBI_33232) + +- [food additive](http://purl.obolibrary.org/obo/CHEBI_64047) SubClassOf [food component](http://purl.obolibrary.org/obo/CHEBI_78295) + + + +### food component `http://purl.obolibrary.org/obo/CHEBI_78295` +#### Removed +- [food component](http://purl.obolibrary.org/obo/CHEBI_78295) [label](http://www.w3.org/2000/01/rdf-schema#label) "food component" + +- [food component](http://purl.obolibrary.org/obo/CHEBI_78295) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dietary components" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [food component](http://purl.obolibrary.org/obo/CHEBI_78295) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:78295" + +- [food component](http://purl.obolibrary.org/obo/CHEBI_78295) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants." + +- [food component](http://purl.obolibrary.org/obo/CHEBI_78295) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dietary component" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [food component](http://purl.obolibrary.org/obo/CHEBI_78295) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [food component](http://purl.obolibrary.org/obo/CHEBI_78295) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "food components" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [food component](http://purl.obolibrary.org/obo/CHEBI_78295) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [food component](http://purl.obolibrary.org/obo/CHEBI_78295) + +- [food component](http://purl.obolibrary.org/obo/CHEBI_78295) SubClassOf [physiological role](http://purl.obolibrary.org/obo/CHEBI_52211) + + + +### food packaging gas `http://purl.obolibrary.org/obo/CHEBI_77974` +#### Removed +- [food packaging gas](http://purl.obolibrary.org/obo/CHEBI_77974) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [food packaging gas](http://purl.obolibrary.org/obo/CHEBI_77974) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:77974" + +- [food packaging gas](http://purl.obolibrary.org/obo/CHEBI_77974) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [food packaging gas](http://purl.obolibrary.org/obo/CHEBI_77974) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Packaging_gas" + +- [food packaging gas](http://purl.obolibrary.org/obo/CHEBI_77974) [label](http://www.w3.org/2000/01/rdf-schema#label) "food packaging gas" + +- [food packaging gas](http://purl.obolibrary.org/obo/CHEBI_77974) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container." + +- [food packaging gas](http://purl.obolibrary.org/obo/CHEBI_77974) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "food packaging gases" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [food packaging gas](http://purl.obolibrary.org/obo/CHEBI_77974) + +- [food packaging gas](http://purl.obolibrary.org/obo/CHEBI_77974) SubClassOf [food additive](http://purl.obolibrary.org/obo/CHEBI_64047) + + + +### food preservative `http://purl.obolibrary.org/obo/CHEBI_65255` +#### Removed +- [food preservative](http://purl.obolibrary.org/obo/CHEBI_65255) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [food preservative](http://purl.obolibrary.org/obo/CHEBI_65255) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes." + +- [food preservative](http://purl.obolibrary.org/obo/CHEBI_65255) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [food preservative](http://purl.obolibrary.org/obo/CHEBI_65255) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:65255" + +- [food preservative](http://purl.obolibrary.org/obo/CHEBI_65255) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "food preservatives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [food preservative](http://purl.obolibrary.org/obo/CHEBI_65255) [label](http://www.w3.org/2000/01/rdf-schema#label) "food preservative" + +- Class: [food preservative](http://purl.obolibrary.org/obo/CHEBI_65255) + +- [food preservative](http://purl.obolibrary.org/obo/CHEBI_65255) SubClassOf [food additive](http://purl.obolibrary.org/obo/CHEBI_64047) + + + +### formate `http://purl.obolibrary.org/obo/CHEBI_15740` +#### Removed +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17190852" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14276" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "44.99820" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:71-47-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)/p-1" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H]C([O-])=O" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Formate" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aminate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00058" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:1901205" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "methanoate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "formiate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [mass](http://purl.obolibrary.org/obo/chebi/mass) "45.01744" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "BDAGIHXWWSANSR-UHFFFAOYSA-M" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:FORMATE" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "formic acid, ion(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [label](http://www.w3.org/2000/01/rdf-schema#label) "formate" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:15740" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "formylate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:1901205" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:71-47-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UM-BBD_compID:c0106" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "UM-BBD" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects." + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24081" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:3946945" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrogen carboxylate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:1006" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CHO2" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000142" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HCO2 anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- Class: [formate](http://purl.obolibrary.org/obo/CHEBI_15740) + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) + +- [formate](http://purl.obolibrary.org/obo/CHEBI_15740) SubClassOf [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) + + + +### formate biosynthetic process `http://purl.obolibrary.org/obo/GO_0015943` +#### Removed +- [formate biosynthetic process](http://purl.obolibrary.org/obo/GO_0015943) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formic acid biosynthetic process" + +- [formate biosynthetic process](http://purl.obolibrary.org/obo/GO_0015943) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015943" + +- [formate biosynthetic process](http://purl.obolibrary.org/obo/GO_0015943) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formate formation" + +- [formate biosynthetic process](http://purl.obolibrary.org/obo/GO_0015943) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formate anabolism" + +- [formate biosynthetic process](http://purl.obolibrary.org/obo/GO_0015943) [label](http://www.w3.org/2000/01/rdf-schema#label) "formate biosynthetic process" + +- [formate biosynthetic process](http://purl.obolibrary.org/obo/GO_0015943) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formate biosynthesis" + +- [formate biosynthetic process](http://purl.obolibrary.org/obo/GO_0015943) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [formate biosynthetic process](http://purl.obolibrary.org/obo/GO_0015943) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formic acid biosynthesis" + +- [formate biosynthetic process](http://purl.obolibrary.org/obo/GO_0015943) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [formate biosynthetic process](http://purl.obolibrary.org/obo/GO_0015943) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formate synthesis" + +- Class: [formate biosynthetic process](http://purl.obolibrary.org/obo/GO_0015943) + +- [formate biosynthetic process](http://purl.obolibrary.org/obo/GO_0015943) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [formate](http://purl.obolibrary.org/obo/CHEBI_15740)) + +- [formate biosynthetic process](http://purl.obolibrary.org/obo/GO_0015943) SubClassOf [monocarboxylic acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0072330) + +- [formate biosynthetic process](http://purl.obolibrary.org/obo/GO_0015943) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [formate](http://purl.obolibrary.org/obo/CHEBI_15740) + +- [formate biosynthetic process](http://purl.obolibrary.org/obo/GO_0015943) SubClassOf [formate metabolic process](http://purl.obolibrary.org/obo/GO_0015942) + + + +### formate catabolic process `http://purl.obolibrary.org/obo/GO_0042183` +#### Removed +- [formate catabolic process](http://purl.obolibrary.org/obo/GO_0042183) [label](http://www.w3.org/2000/01/rdf-schema#label) "formate catabolic process" + +- [formate catabolic process](http://purl.obolibrary.org/obo/GO_0042183) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formic acid catabolism" + +- [formate catabolic process](http://purl.obolibrary.org/obo/GO_0042183) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [formate catabolic process](http://purl.obolibrary.org/obo/GO_0042183) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formate breakdown" + +- [formate catabolic process](http://purl.obolibrary.org/obo/GO_0042183) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formic acid catabolic process" + +- [formate catabolic process](http://purl.obolibrary.org/obo/GO_0042183) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0042183" + +- [formate catabolic process](http://purl.obolibrary.org/obo/GO_0042183) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [formate catabolic process](http://purl.obolibrary.org/obo/GO_0042183) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formate degradation" + +- [formate catabolic process](http://purl.obolibrary.org/obo/GO_0042183) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formate catabolism" + +- Class: [formate catabolic process](http://purl.obolibrary.org/obo/GO_0042183) + +- [formate catabolic process](http://purl.obolibrary.org/obo/GO_0042183) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [formate](http://purl.obolibrary.org/obo/CHEBI_15740)) + +- [formate catabolic process](http://purl.obolibrary.org/obo/GO_0042183) SubClassOf [formate metabolic process](http://purl.obolibrary.org/obo/GO_0015942) + +- [formate catabolic process](http://purl.obolibrary.org/obo/GO_0042183) SubClassOf [monocarboxylic acid catabolic process](http://purl.obolibrary.org/obo/GO_0072329) + +- [formate catabolic process](http://purl.obolibrary.org/obo/GO_0042183) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [formate](http://purl.obolibrary.org/obo/CHEBI_15740) + + + +### formate metabolic process `http://purl.obolibrary.org/obo/GO_0015942` +#### Removed +- [formate metabolic process](http://purl.obolibrary.org/obo/GO_0015942) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [formate metabolic process](http://purl.obolibrary.org/obo/GO_0015942) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formate metabolism" + +- [formate metabolic process](http://purl.obolibrary.org/obo/GO_0015942) [label](http://www.w3.org/2000/01/rdf-schema#label) "formate metabolic process" + +- [formate metabolic process](http://purl.obolibrary.org/obo/GO_0015942) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015942" + +- [formate metabolic process](http://purl.obolibrary.org/obo/GO_0015942) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- Class: [formate metabolic process](http://purl.obolibrary.org/obo/GO_0015942) + +- [formate metabolic process](http://purl.obolibrary.org/obo/GO_0015942) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [formate](http://purl.obolibrary.org/obo/CHEBI_15740)) + +- [formate metabolic process](http://purl.obolibrary.org/obo/GO_0015942) SubClassOf [monocarboxylic acid metabolic process](http://purl.obolibrary.org/obo/GO_0032787) + +- [formate metabolic process](http://purl.obolibrary.org/obo/GO_0015942) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [formate](http://purl.obolibrary.org/obo/CHEBI_15740) + + + +### formate transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015499` +#### Removed +- [formate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015499) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "formate uptake transmembrane transporter activity" + +- [formate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015499) [label](http://www.w3.org/2000/01/rdf-schema#label) "formate transmembrane transporter activity" + +- [formate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015499) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [formate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015499) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "RHEA:29679" + +- [formate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015499) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of formate from one side of a membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [formate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015499) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0015659" + +- [formate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015499) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015499" + +- [formate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015499) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formate uptake permease activity" + +- Class: [formate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015499) + +- [formate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015499) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [formate](http://purl.obolibrary.org/obo/CHEBI_15740)) + +- [formate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015499) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [formate transport](http://purl.obolibrary.org/obo/GO_0015724) + +- [formate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015499) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [formate](http://purl.obolibrary.org/obo/CHEBI_15740) + +- [formate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015499) SubClassOf [carboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046943) + + + +### formate transport `http://purl.obolibrary.org/obo/GO_0015724` +#### Removed +- [formate transport](http://purl.obolibrary.org/obo/GO_0015724) [label](http://www.w3.org/2000/01/rdf-schema#label) "formate transport" + +- [formate transport](http://purl.obolibrary.org/obo/GO_0015724) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of formate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [formate transport](http://purl.obolibrary.org/obo/GO_0015724) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [formate transport](http://purl.obolibrary.org/obo/GO_0015724) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015724" + +- Class: [formate transport](http://purl.obolibrary.org/obo/GO_0015724) + +- [formate transport](http://purl.obolibrary.org/obo/GO_0015724) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [formate](http://purl.obolibrary.org/obo/CHEBI_15740)) + +- [formate transport](http://purl.obolibrary.org/obo/GO_0015724) SubClassOf [monocarboxylic acid transport](http://purl.obolibrary.org/obo/GO_0015718) + +- [formate transport](http://purl.obolibrary.org/obo/GO_0015724) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [formate](http://purl.obolibrary.org/obo/CHEBI_15740) + + + +### formed as result of `http://purl.obolibrary.org/obo/RO_0002354` +#### Removed +- [formed as result of](http://purl.obolibrary.org/obo/RO_0002354) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [formed as result of](http://purl.obolibrary.org/obo/RO_0002354) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### formic acid `http://purl.obolibrary.org/obo/CHEBI_30751` +#### Removed +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:7361809" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H]C(O)=O" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5145" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18397576" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:14637377" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "methoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00001182" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22622393" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:1209246" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bilorin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:FORMATE" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16230297" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:64-18-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB01942" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:FMT" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:64-18-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22385261" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "FORMIC ACID" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000142" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LIPID_MAPS_instance:LMFA01010040" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "LIPID MAPS" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16120414" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22447125" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16222862" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CH2O2" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrogen carboxylic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BPDB:1749" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16445901" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Methanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "BDAGIHXWWSANSR-UHFFFAOYSA-N" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Acide formique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22304812" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ameisensaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aminic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22080171" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22483350" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18034701" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "46.00548" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "H-COOH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24082" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [mass](http://purl.obolibrary.org/obo/chebi/mass) "46.02538" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:30751" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15811469" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HCOOH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16185830" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Formic_acid" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:64-18-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HCO2H" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Patent:CN101481304" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:1209246" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:3946945" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22606986" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12591956" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [label](http://www.w3.org/2000/01/rdf-schema#label) "formic acid" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "formylic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Formic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22499553" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:1008" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects." + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:42460" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22280475" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16465784" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00058" + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22540994" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- Class: [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [protic solvent](http://purl.obolibrary.org/obo/CHEBI_48356) + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [formate](http://purl.obolibrary.org/obo/CHEBI_15740) + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [antibacterial agent](http://purl.obolibrary.org/obo/CHEBI_33282) + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [astringent](http://purl.obolibrary.org/obo/CHEBI_74783) + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) + +- [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) SubClassOf [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) + + + +### formic acid secretion `http://purl.obolibrary.org/obo/GO_0046721` +#### Removed +- [formic acid secretion](http://purl.obolibrary.org/obo/GO_0046721) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046721" + +- [formic acid secretion](http://purl.obolibrary.org/obo/GO_0046721) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formate secretion" + +- [formic acid secretion](http://purl.obolibrary.org/obo/GO_0046721) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [formic acid secretion](http://purl.obolibrary.org/obo/GO_0046721) [label](http://www.w3.org/2000/01/rdf-schema#label) "formic acid secretion" + +- [formic acid secretion](http://purl.obolibrary.org/obo/GO_0046721) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The controlled release of formic acid, HCOOH, by a cell or a tissue." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- Class: [formic acid secretion](http://purl.obolibrary.org/obo/GO_0046721) + +- [formic acid secretion](http://purl.obolibrary.org/obo/GO_0046721) EquivalentTo [secretion](http://purl.obolibrary.org/obo/GO_0046903) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [formate](http://purl.obolibrary.org/obo/CHEBI_15740)) + +- [formic acid secretion](http://purl.obolibrary.org/obo/GO_0046721) SubClassOf [acid secretion](http://purl.obolibrary.org/obo/GO_0046717) + +- [formic acid secretion](http://purl.obolibrary.org/obo/GO_0046721) SubClassOf [formate transport](http://purl.obolibrary.org/obo/GO_0015724) + + + +### formula `http://purl.obolibrary.org/obo/chebi/formula` +#### Removed +- AnnotationProperty: [formula](http://purl.obolibrary.org/obo/chebi/formula) + + + +### formyl group `http://purl.obolibrary.org/obo/CHEBI_42485` +#### Removed +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CHO" + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:FOR" + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "FORMYL GROUP" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Fo" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CBN" + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24089" + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H]C(*)=O" + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:42480" + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "formyl" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [mass](http://purl.obolibrary.org/obo/chebi/mass) "29.01804" + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "29.00274" + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "-CH(O)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "H-CO-" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [label](http://www.w3.org/2000/01/rdf-schema#label) "formyl group" + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:42485" + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "-CHO" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aldehyde group" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "methanoyl" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "carbaldehyde" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) SubClassOf [is_substituent_group_from](http://purl.obolibrary.org/obo/chebi#is_substituent_group_from) some [formic acid](http://purl.obolibrary.org/obo/CHEBI_30751) + +- [formyl group](http://purl.obolibrary.org/obo/CHEBI_42485) SubClassOf [univalent carboacyl group](http://purl.obolibrary.org/obo/CHEBI_27207) + + + +### fraction A pre-pro B cell `http://purl.obolibrary.org/obo/CL_0002045` +#### Removed +- [fraction A pre-pro B cell](http://purl.obolibrary.org/obo/CL_0002045) EquivalentTo [pro-B cell](http://purl.obolibrary.org/obo/CL_0000826) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [glutamyl aminopeptidase](http://purl.obolibrary.org/obo/PR_000002039)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980)) + +- [fraction A pre-pro B cell](http://purl.obolibrary.org/obo/CL_0002045) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980) + +- [fraction A pre-pro B cell](http://purl.obolibrary.org/obo/CL_0002045) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [glutamyl aminopeptidase](http://purl.obolibrary.org/obo/PR_000002039) + +#### Added +- [fraction A pre-pro B cell](http://purl.obolibrary.org/obo/CL_0002045) EquivalentTo [pro-B cell](http://purl.obolibrary.org/obo/CL_0000826) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [glutamyl aminopeptidase](http://purl.obolibrary.org/obo/PR_000002039)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) + +- [fraction A pre-pro B cell](http://purl.obolibrary.org/obo/CL_0002045) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [glutamyl aminopeptidase](http://purl.obolibrary.org/obo/PR_000002039) + +- [fraction A pre-pro B cell](http://purl.obolibrary.org/obo/CL_0002045) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980) + + +### fraction B precursor B cell `http://purl.obolibrary.org/obo/CL_0002047` +#### Removed +- [fraction B precursor B cell](http://purl.obolibrary.org/obo/CL_0002047) EquivalentTo [fraction B/C precursor B cell](http://purl.obolibrary.org/obo/CL_0002400) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [glutamyl aminopeptidase](http://purl.obolibrary.org/obo/PR_000002039)) + +- [fraction B precursor B cell](http://purl.obolibrary.org/obo/CL_0002047) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [glutamyl aminopeptidase](http://purl.obolibrary.org/obo/PR_000002039) + +#### Added +- [fraction B precursor B cell](http://purl.obolibrary.org/obo/CL_0002047) EquivalentTo [fraction B/C precursor B cell](http://purl.obolibrary.org/obo/CL_0002400) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [glutamyl aminopeptidase](http://purl.obolibrary.org/obo/PR_000002039)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) + +- [fraction B precursor B cell](http://purl.obolibrary.org/obo/CL_0002047) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [glutamyl aminopeptidase](http://purl.obolibrary.org/obo/PR_000002039) + + +### fraction B/C precursor B cell `http://purl.obolibrary.org/obo/CL_0002400` +#### Removed +- [fraction B/C precursor B cell](http://purl.obolibrary.org/obo/CL_0002400) EquivalentTo [precursor B cell](http://purl.obolibrary.org/obo/CL_0000817) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) + +#### Added +- [fraction B/C precursor B cell](http://purl.obolibrary.org/obo/CL_0002400) EquivalentTo [precursor B cell](http://purl.obolibrary.org/obo/CL_0000817) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) + + +### fraction C precursor B cell `http://purl.obolibrary.org/obo/CL_0002049` +#### Removed +- [fraction C precursor B cell](http://purl.obolibrary.org/obo/CL_0002049) EquivalentTo [fraction B/C precursor B cell](http://purl.obolibrary.org/obo/CL_0002400) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [immunoglobulin iota chain](http://purl.obolibrary.org/obo/PR_000001858)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [immunoglobulin lambda-like polypeptide 1](http://purl.obolibrary.org/obo/PR_000001859)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [glutamyl aminopeptidase](http://purl.obolibrary.org/obo/PR_000002039)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [V(D)J recombination-activating protein 1](http://purl.obolibrary.org/obo/PR_000003457)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [V(D)J recombination-activating protein 2](http://purl.obolibrary.org/obo/PR_000003460)) and ([has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [immunoglobulin heavy chain V-D-J recombination](http://purl.obolibrary.org/obo/GO_0071707)) + +- [fraction C precursor B cell](http://purl.obolibrary.org/obo/CL_0002049) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [immunoglobulin heavy chain V-D-J recombination](http://purl.obolibrary.org/obo/GO_0071707) + +#### Added +- [fraction C precursor B cell](http://purl.obolibrary.org/obo/CL_0002049) EquivalentTo [fraction B/C precursor B cell](http://purl.obolibrary.org/obo/CL_0002400) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [immunoglobulin iota chain](http://purl.obolibrary.org/obo/PR_000001858)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [immunoglobulin lambda-like polypeptide 1](http://purl.obolibrary.org/obo/PR_000001859)) and ([has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [immunoglobulin heavy chain V-D-J recombination](http://purl.obolibrary.org/obo/GO_0071707)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [glutamyl aminopeptidase](http://purl.obolibrary.org/obo/PR_000002039)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [V(D)J recombination-activating protein 1](http://purl.obolibrary.org/obo/PR_000003457)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [V(D)J recombination-activating protein 2](http://purl.obolibrary.org/obo/PR_000003460)) + +- [fraction C precursor B cell](http://purl.obolibrary.org/obo/CL_0002049) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [immunoglobulin heavy chain V-D-J recombination](http://purl.obolibrary.org/obo/GO_0071707) + + +### fraction D precursor B cell `http://purl.obolibrary.org/obo/CL_0002052` +#### Removed +- [fraction D precursor B cell](http://purl.obolibrary.org/obo/CL_0002052) EquivalentTo [precursor B cell](http://purl.obolibrary.org/obo/CL_0000817) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [glutamyl aminopeptidase](http://purl.obolibrary.org/obo/PR_000002039)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [immunoglobulin light chain V-J recombination](http://purl.obolibrary.org/obo/GO_0071708)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [pre-B cell receptor complex](http://purl.obolibrary.org/obo/GO_0035369)) + +- [fraction D precursor B cell](http://purl.obolibrary.org/obo/CL_0002052) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [immunoglobulin light chain V-J recombination](http://purl.obolibrary.org/obo/GO_0071708) + +- [fraction D precursor B cell](http://purl.obolibrary.org/obo/CL_0002052) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [pre-B cell receptor complex](http://purl.obolibrary.org/obo/GO_0035369) + +#### Added +- [fraction D precursor B cell](http://purl.obolibrary.org/obo/CL_0002052) EquivalentTo [precursor B cell](http://purl.obolibrary.org/obo/CL_0000817) and ([has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [immunoglobulin light chain V-J recombination](http://purl.obolibrary.org/obo/GO_0071708)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [pre-B cell receptor complex](http://purl.obolibrary.org/obo/GO_0035369)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [glutamyl aminopeptidase](http://purl.obolibrary.org/obo/PR_000002039)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) + +- [fraction D precursor B cell](http://purl.obolibrary.org/obo/CL_0002052) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [immunoglobulin light chain V-J recombination](http://purl.obolibrary.org/obo/GO_0071708) + +- [fraction D precursor B cell](http://purl.obolibrary.org/obo/CL_0002052) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [pre-B cell receptor complex](http://purl.obolibrary.org/obo/GO_0035369) + + +### fraction E immature B cell `http://purl.obolibrary.org/obo/CL_0002054` +#### Removed +- [fraction E immature B cell](http://purl.obolibrary.org/obo/CL_0002054) EquivalentTo [immature B cell](http://purl.obolibrary.org/obo/CL_0000816) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) + +- [fraction E immature B cell](http://purl.obolibrary.org/obo/CL_0002054) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + +- [fraction E immature B cell](http://purl.obolibrary.org/obo/CL_0002054) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +#### Added +- [fraction E immature B cell](http://purl.obolibrary.org/obo/CL_0002054) EquivalentTo [immature B cell](http://purl.obolibrary.org/obo/CL_0000816) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) + +- [fraction E immature B cell](http://purl.obolibrary.org/obo/CL_0002054) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + +- [fraction E immature B cell](http://purl.obolibrary.org/obo/CL_0002054) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + + +### fraction F mature B cell `http://purl.obolibrary.org/obo/CL_0002056` +#### Removed +- [fraction F mature B cell](http://purl.obolibrary.org/obo/CL_0002056) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) + +- [fraction F mature B cell](http://purl.obolibrary.org/obo/CL_0002056) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037) + +- [fraction F mature B cell](http://purl.obolibrary.org/obo/CL_0002056) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880) + +#### Added +- [fraction F mature B cell](http://purl.obolibrary.org/obo/CL_0002056) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RABC](http://purl.obolibrary.org/obo/PR_000001014)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338)) + +- [fraction F mature B cell](http://purl.obolibrary.org/obo/CL_0002056) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880) + +- [fraction F mature B cell](http://purl.obolibrary.org/obo/CL_0002056) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037) + + +### functionally related to `http://purl.obolibrary.org/obo/RO_0002328` +#### Removed +- [functionally related to](http://purl.obolibrary.org/obo/RO_0002328) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [functionally related to](http://purl.obolibrary.org/obo/RO_0002328) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### fundamental metabolite `http://purl.obolibrary.org/obo/CHEBI_78675` +#### Removed +- [fundamental metabolite](http://purl.obolibrary.org/obo/CHEBI_78675) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "essential metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fundamental metabolite](http://purl.obolibrary.org/obo/CHEBI_78675) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "essential metabolite" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fundamental metabolite](http://purl.obolibrary.org/obo/CHEBI_78675) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [fundamental metabolite](http://purl.obolibrary.org/obo/CHEBI_78675) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:78675" + +- [fundamental metabolite](http://purl.obolibrary.org/obo/CHEBI_78675) [label](http://www.w3.org/2000/01/rdf-schema#label) "fundamental metabolite" + +- [fundamental metabolite](http://purl.obolibrary.org/obo/CHEBI_78675) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [fundamental metabolite](http://purl.obolibrary.org/obo/CHEBI_78675) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fundamental metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fundamental metabolite](http://purl.obolibrary.org/obo/CHEBI_78675) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any metabolite produced by all living cells." + +- Class: [fundamental metabolite](http://purl.obolibrary.org/obo/CHEBI_78675) + +- [fundamental metabolite](http://purl.obolibrary.org/obo/CHEBI_78675) SubClassOf [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) + + + +### fundamental particle `http://purl.obolibrary.org/obo/CHEBI_33233` +#### Removed +- [fundamental particle](http://purl.obolibrary.org/obo/CHEBI_33233) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "elementary particles" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fundamental particle](http://purl.obolibrary.org/obo/CHEBI_33233) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "elementary particle" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [fundamental particle](http://purl.obolibrary.org/obo/CHEBI_33233) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33233" + +- [fundamental particle](http://purl.obolibrary.org/obo/CHEBI_33233) [label](http://www.w3.org/2000/01/rdf-schema#label) "fundamental particle" + +- [fundamental particle](http://purl.obolibrary.org/obo/CHEBI_33233) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [fundamental particle](http://purl.obolibrary.org/obo/CHEBI_33233) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A particle not known to have substructure." + +- [fundamental particle](http://purl.obolibrary.org/obo/CHEBI_33233) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [fundamental particle](http://purl.obolibrary.org/obo/CHEBI_33233) + +- [fundamental particle](http://purl.obolibrary.org/obo/CHEBI_33233) SubClassOf [subatomic particle](http://purl.obolibrary.org/obo/CHEBI_36342) + + + +### fungal metabolite `http://purl.obolibrary.org/obo/CHEBI_76946` +#### Removed +- [fungal metabolite](http://purl.obolibrary.org/obo/CHEBI_76946) [label](http://www.w3.org/2000/01/rdf-schema#label) "fungal metabolite" + +- [fungal metabolite](http://purl.obolibrary.org/obo/CHEBI_76946) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:76947" + +- [fungal metabolite](http://purl.obolibrary.org/obo/CHEBI_76946) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:75765" + +- [fungal metabolite](http://purl.obolibrary.org/obo/CHEBI_76946) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:76946" + +- [fungal metabolite](http://purl.obolibrary.org/obo/CHEBI_76946) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fungal metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [fungal metabolite](http://purl.obolibrary.org/obo/CHEBI_76946) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [fungal metabolite](http://purl.obolibrary.org/obo/CHEBI_76946) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [fungal metabolite](http://purl.obolibrary.org/obo/CHEBI_76946) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds." + +- Class: [fungal metabolite](http://purl.obolibrary.org/obo/CHEBI_76946) + +- [fungal metabolite](http://purl.obolibrary.org/obo/CHEBI_76946) SubClassOf [eukaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75763) + + + +### gamma-amino acid `http://purl.obolibrary.org/obo/CHEBI_33707` +#### Removed +- [gamma-amino acid](http://purl.obolibrary.org/obo/CHEBI_33707) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A non-proteinogenic amino-acid in which the amino group is located on the carbon atom at the position gamma to the carboxy group." + +- [gamma-amino acid](http://purl.obolibrary.org/obo/CHEBI_33707) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gamma-amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [gamma-amino acid](http://purl.obolibrary.org/obo/CHEBI_33707) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "gamma-amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [gamma-amino acid](http://purl.obolibrary.org/obo/CHEBI_33707) [label](http://www.w3.org/2000/01/rdf-schema#label) "gamma-amino acid" + +- [gamma-amino acid](http://purl.obolibrary.org/obo/CHEBI_33707) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [gamma-amino acid](http://purl.obolibrary.org/obo/CHEBI_33707) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gamma-amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [gamma-amino acid](http://purl.obolibrary.org/obo/CHEBI_33707) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [gamma-amino acid](http://purl.obolibrary.org/obo/CHEBI_33707) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "gamma-amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [gamma-amino acid](http://purl.obolibrary.org/obo/CHEBI_33707) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33707" + +- Class: [gamma-amino acid](http://purl.obolibrary.org/obo/CHEBI_33707) + +- [gamma-amino acid](http://purl.obolibrary.org/obo/CHEBI_33707) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [gamma-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_71666) + +- [gamma-amino acid](http://purl.obolibrary.org/obo/CHEBI_33707) SubClassOf [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) + + + +### gamma-amino acid anion `http://purl.obolibrary.org/obo/CHEBI_71666` +#### Removed +- [gamma-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_71666) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:71666" + +- [gamma-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_71666) [label](http://www.w3.org/2000/01/rdf-schema#label) "gamma-amino acid anion" + +- [gamma-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_71666) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gamma-amino acid anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [gamma-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_71666) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [gamma-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_71666) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An amino-acid anion in which the amino group is situated gamma- to the carboxylate group." + +- [gamma-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_71666) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [gamma-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_71666) + +- [gamma-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_71666) SubClassOf [amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_37022) + +- [gamma-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_71666) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [gamma-amino acid](http://purl.obolibrary.org/obo/CHEBI_33707) + + + +### gamma-aminobutyrate `http://purl.obolibrary.org/obo/CHEBI_30566` +#### Removed +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "BTCSSZJGUNDROE-UHFFFAOYSA-M" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "NCCCC([O-])=O" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12509893" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-aminobutanoic acid ion (1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00334" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:559138" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:20317" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C4H8NO2" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [mass](http://purl.obolibrary.org/obo/chebi/mass) "102.11186" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gamma-aminobutyrate anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gamma-aminobutanoate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:11961" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:3536873" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-Amino-butyrat" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:3536873" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)/p-1" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An gamma-amino acid anion resulting from the deprotonation of the carboxy group of gamma-aminobutyric acid." + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [label](http://www.w3.org/2000/01/rdf-schema#label) "gamma-aminobutyrate" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "4-aminobutanoate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "102.05605" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-aminobutyrate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-Aminobutylate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:30566" + +- Class: [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) SubClassOf [gamma-amino acid anion](http://purl.obolibrary.org/obo/CHEBI_71666) + +- [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) + + + +### gamma-aminobutyric acid `http://purl.obolibrary.org/obo/CHEBI_16865` +#### Removed +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10930630" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "InChIKey=BTCSSZJGUNDROE-UHFFFAOYSA-N" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [InChIKey](http://purl.obolibrary.org/obo/fbbt#InChIKey) + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:906818" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [label](http://www.w3.org/2000/01/rdf-schema#label) "gamma-aminobutyric acid" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22770225" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LIPID_MAPS_instance:LMFA01100039" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "LIPID MAPS" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "gamma-Aminobutyric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:4-AMINO-BUTYRATE" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An amino fatty acid composed of butanoic acid with the amino substituent at C-4." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "GAMMA-AMINO-BUTANOIC ACID" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-Aminobutyric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "103.06333" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:20318" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "4-aminobutanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:40483" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:1262" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Gamma-Aminobutyric_acid" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "4-aminobutanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-aminobutyric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "gamma-aminobutyric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST Chemistry WebBook:" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "piperidinic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "piperidic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus:" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [InChI](http://purl.obolibrary.org/obo/fbbt#InChI) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21614609" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gamma-amino-n-butyric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST Chemistry WebBook:" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:1786" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "gamma-aminobutyric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "GABA" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPHAR" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "piperidinic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus:" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00001337" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gamma-aminobutanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gamma-aminobutanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST Chemistry WebBook:" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:49775" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "piperidic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "NCCCC(O)=O" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-aminobutanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt:" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:906818" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A gamma-amino acid that is butanoic acid with the amino substituent located at C-4." + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "gamma-Aminobutyric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-Aminobutyric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:16865" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "GAMMA-AMINO-BUTANOIC ACID" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00334" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "BTCSSZJGUNDROE-UHFFFAOYSA-N" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BPDB:2298" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:193777" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-aminobutanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "omega-aminobutyric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gamma-amino-n-butyric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10630630" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C4H9NO2" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D00058" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-Aminobutanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:56-12-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-aminobutanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "GABA" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:56-12-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gamma-Aminobuttersaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB02530" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16276116" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:ABU" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [mass](http://purl.obolibrary.org/obo/chebi/mass) "103.11980" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "C4H9NO2" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [FORMULA](http://purl.obolibrary.org/obo/fbbt#FORMULA) + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-aminobutyric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-Aminobutanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "omega-aminobutyric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST Chemistry WebBook:" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NCCCC(O)=O" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [SMILES](http://purl.obolibrary.org/obo/fbbt#SMILES) + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000112" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gamma-Aminobuttersaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST Chemistry WebBook:" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4Abu" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "GABA" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPHAR:" + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:56-12-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- Class: [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [gamma-aminobutyrate](http://purl.obolibrary.org/obo/CHEBI_30566) + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) SubClassOf [is_tautomer_of](http://purl.obolibrary.org/obo/chebi#is_tautomer_of) some [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) SubClassOf [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [butyric acid](http://purl.obolibrary.org/obo/CHEBI_30772) + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) SubClassOf [gamma-amino acid](http://purl.obolibrary.org/obo/CHEBI_33707) + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [signalling molecule](http://purl.obolibrary.org/obo/CHEBI_62488) + +- [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [neurotransmitter](http://purl.obolibrary.org/obo/CHEBI_25512) + + + +### gamma-aminobutyric acid biosynthetic process `http://purl.obolibrary.org/obo/GO_0009449` +#### Removed +- [gamma-aminobutyric acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009449) SubClassOf [organic substance biosynthetic process](http://purl.obolibrary.org/obo/GO_1901576) + +#### Added +- [gamma-aminobutyric acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009449) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### gamma-aminobutyric acid catabolic process `http://purl.obolibrary.org/obo/GO_0009450` +#### Removed +- [gamma-aminobutyric acid catabolic process](http://purl.obolibrary.org/obo/GO_0009450) SubClassOf [organic substance catabolic process](http://purl.obolibrary.org/obo/GO_1901575) + +#### Added +- [gamma-aminobutyric acid catabolic process](http://purl.obolibrary.org/obo/GO_0009450) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### gamma-aminobutyric acid secretion, neurotransmission `http://purl.obolibrary.org/obo/GO_0061534` + +#### Added +- [gamma-aminobutyric acid secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061534) EquivalentTo [neurotransmitter secretion](http://purl.obolibrary.org/obo/GO_0007269) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888)) + + +### gamma-aminobutyric acid transport `http://purl.obolibrary.org/obo/GO_0015812` +#### Removed +- [gamma-aminobutyric acid transport](http://purl.obolibrary.org/obo/GO_0015812) SubClassOf [organic substance transport](http://purl.obolibrary.org/obo/GO_0071702) + +#### Added +- [gamma-aminobutyric acid transport](http://purl.obolibrary.org/obo/GO_0015812) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### gamma-aminobutyric acid zwitterion `http://purl.obolibrary.org/obo/CHEBI_59888` +#### Removed +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C4H9NO2" + +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Zwitterionic form of gamma-aminobutyric acid having an anionic carboxy group and a protonated amino group." + +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-ammoniobutanoate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "BTCSSZJGUNDROE-UHFFFAOYSA-N" + +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) [mass](http://purl.obolibrary.org/obo/chebi/mass) "103.11980" + +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)" + +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[NH3+]CCCC([O-])=O" + +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) [label](http://www.w3.org/2000/01/rdf-schema#label) "gamma-aminobutyric acid zwitterion" + +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:59888" + +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:1041559" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-aminobutanoate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "4-azaniumylbutanoate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "103.06333" + +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) SubClassOf [is_tautomer_of](http://purl.obolibrary.org/obo/chebi#is_tautomer_of) some [gamma-aminobutyric acid](http://purl.obolibrary.org/obo/CHEBI_16865) + +- [gamma-aminobutyric acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_59888) SubClassOf [amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_35238) + + + +### gamma-delta thymocyte `http://purl.obolibrary.org/obo/CL_0002405` +#### Removed +- [gamma-delta thymocyte](http://purl.obolibrary.org/obo/CL_0002405) EquivalentTo [thymocyte](http://purl.obolibrary.org/obo/CL_0000893) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [gamma-delta T cell receptor complex](http://purl.obolibrary.org/obo/GO_0042106)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) + +#### Added +- [gamma-delta thymocyte](http://purl.obolibrary.org/obo/CL_0002405) EquivalentTo [thymocyte](http://purl.obolibrary.org/obo/CL_0000893) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [gamma-delta T cell receptor complex](http://purl.obolibrary.org/obo/GO_0042106)) + + +### gas molecular entity `http://purl.obolibrary.org/obo/CHEBI_138675` +#### Removed +- [gas molecular entity](http://purl.obolibrary.org/obo/CHEBI_138675) [label](http://www.w3.org/2000/01/rdf-schema#label) "gas molecular entity" + +- [gas molecular entity](http://purl.obolibrary.org/obo/CHEBI_138675) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gas molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [gas molecular entity](http://purl.obolibrary.org/obo/CHEBI_138675) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:138675" + +- [gas molecular entity](http://purl.obolibrary.org/obo/CHEBI_138675) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [gas molecular entity](http://purl.obolibrary.org/obo/CHEBI_138675) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [gas molecular entity](http://purl.obolibrary.org/obo/CHEBI_138675) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa)." + +- [gas molecular entity](http://purl.obolibrary.org/obo/CHEBI_138675) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gaseous molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [gas molecular entity](http://purl.obolibrary.org/obo/CHEBI_138675) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:https://en.wikipedia.org/wiki/Gas" + +- [gas molecular entity](http://purl.obolibrary.org/obo/CHEBI_138675) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gaseous molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [gas molecular entity](http://purl.obolibrary.org/obo/CHEBI_138675) + +- [gas molecular entity](http://purl.obolibrary.org/obo/CHEBI_138675) SubClassOf [main group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33579) + + + +### gastrula cell `http://purl.obolibrary.org/obo/CL_0000361` +#### Removed +- [gastrula cell](http://purl.obolibrary.org/obo/CL_0000361) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### genomically related to `http://purl.obolibrary.org/obo/RO_0002330` +#### Removed +- [genomically related to](http://purl.obolibrary.org/obo/RO_0002330) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [genomically related to](http://purl.obolibrary.org/obo/RO_0002330) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### germ line cell `http://purl.obolibrary.org/obo/CL_0000039` +#### Removed +- [germ line cell](http://purl.obolibrary.org/obo/CL_0000039) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### geroprotector `http://purl.obolibrary.org/obo/CHEBI_176497` +#### Removed +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-aging agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23372317" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28580190" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30885572" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [label](http://www.w3.org/2000/01/rdf-schema#label) "geroprotector" + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:33973253" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "geroprotectors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-aging drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-aging agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anti-aging drug" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "geroprotective agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "geroprotective agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:33144142" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any compound that supports healthy aging, slows the biological aging process, or extends lifespan." + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:176497" + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:34606237" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Geroprotector" + +- Class: [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) + +- [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) SubClassOf [protective agent](http://purl.obolibrary.org/obo/CHEBI_50267) + + + +### ghrelin `http://purl.obolibrary.org/obo/CHEBI_75431` +#### Removed +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23278489" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23631903" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23704134" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C(C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(N1[C@@H](CCC1)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(N2[C@@H](CCC2)C(N3[C@@H](CCC3)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(N4[C@@H](CCC4)C(=O)N[C@H](C(=O)O)CCCNC(=N)N)=O)CCC(=O)N)CC(C)C)CCCCN)C)=O)=O)CCCCN)CCCCN)CO)CCC(=O)O)CCCCN)CCCNC(N)=N)CCC(=O)N)CCC(=O)N)C(C)C)CCCNC(N)=N)CCC(=O)N)CC=5N=CNC5)CCC(=O)O)=O)CO)CC(C)C)CC=6C=CC=CC6)COC(=O)CCCCCCC)CO)N" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23982275" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15788704" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23652386" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lenomorelina" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WHO_MedNet" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:304853-26-7" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28621678" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23316086" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23778458" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23359315" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28538835" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Gly-Ser-Ser(octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23989358" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23965296" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:258279-04-8" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "H-Gly-Ser-Ser(n-octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg-OH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23481295" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Human ghrelin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Motilin-related peptide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28590260" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23524619" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ghrelin (human)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28704966" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23843943" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C149H249N47O42" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23652399" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23808302" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lenomorelin" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WHO_MedNet" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "GNKDKYIHGQKHHM-RJKLHVOGSA-N" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glycyl-L-seryl-O-octanoyl-L-seryl-L-phenylalanyl-L-leucyl-L-seryl-L-prolyl-L-alpha-glutamyl-L-histidyl-L-glutaminyl-L-arginyl-L-valyl-L-glutaminyl-L-glutaminyl-L-arginyl-L-lysyl-L-alpha-glutamyl-L-seryl-L-lysyl-L-lysyl-L-prolyl-L-prolyl-L-alanyl-L-lysyl-L-leucyl-L-glutaminyl-L-prolyl-L-arginine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23652420" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [label](http://www.w3.org/2000/01/rdf-schema#label) "ghrelin" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:24715767" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23804489" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A 28-membered appetite-stimulating polypeptide consisting of Gly, Ser, Ser(octanoyl), Phe, Leu, Ser, Pro, Glu, His, Gln, Arg, Val, Gln, Gln, Arg, Lys, Glu, Ser, Lys, Lys, Pro, Pro, Ala, Lys, Leu, Gln, Pro and Arg residues joined in sequence. The O-n-octanoylation of the side-chain hydroxy group of serine-3 (Ser3) is essential for ghrelin's activity." + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C149H249N47O42/c1-9-10-11-12-16-45-118(209)238-78-106(191-135(225)103(75-197)171-115(204)73-154)137(227)187-101(71-84-32-14-13-15-33-84)133(223)186-100(70-81(4)5)132(222)190-105(77-199)144(234)194-66-29-42-108(194)139(229)180-95(51-57-117(207)208)128(218)188-102(72-85-74-165-79-169-85)134(224)179-92(47-53-112(156)201)126(216)175-90(39-26-63-167-148(161)162)130(220)192-119(82(6)7)141(231)181-93(48-54-113(157)202)127(217)177-91(46-52-111(155)200)125(215)174-89(38-25-62-166-147(159)160)122(212)173-87(35-18-22-59-151)121(211)178-94(50-56-116(205)206)129(219)189-104(76-198)136(226)176-88(36-19-23-60-152)123(213)182-96(37-20-24-61-153)142(232)196-68-31-44-110(196)145(235)195-67-30-41-107(195)138(228)170-83(8)120(210)172-86(34-17-21-58-150)124(214)185-99(69-80(2)3)131(221)183-97(49-55-114(158)203)143(233)193-65-28-43-109(193)140(230)184-98(146(236)237)40-27-64-168-149(163)164/h13-15,32-33,74,79-83,86-110,119,197-199H,9-12,16-31,34-73,75-78,150-154H2,1-8H3,(H2,155,200)(H2,156,201)(H2,157,202)(H2,158,203)(H,165,169)(H,170,228)(H,171,204)(H,172,210)(H,173,212)(H,174,215)(H,175,216)(H,176,226)(H,177,217)(H,178,211)(H,179,224)(H,180,229)(H,181,231)(H,182,213)(H,183,221)(H,184,230)(H,185,214)(H,186,223)(H,187,227)(H,188,218)(H,189,219)(H,190,222)(H,191,225)(H,192,220)(H,205,206)(H,207,208)(H,236,237)(H4,159,160,166)(H4,161,162,167)(H4,163,164,168)/t83-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,119-/m0/s1" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Gastric MLTRP" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "GSS(octanoyl)FLSPEHQRVQQRKESKKPPAKLQPR" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23847595" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28542403" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28547758" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23428971" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "GS-S(n-octanoyl)-FLSPEHQRVQQRKESKKPPAKLQPR" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lenomoreline" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WHO_MedNet" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23307791" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23624808" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23317782" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:75431" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23698230" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C16025" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "3368.87933" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lenomorelinum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WHO_MedNet" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [mass](http://purl.obolibrary.org/obo/chebi/mass) "3370.867" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23178701" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23159561" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ghrelin" + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [apoptosis inducer](http://purl.obolibrary.org/obo/CHEBI_68495) + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [appetite enhancer](http://purl.obolibrary.org/obo/CHEBI_50779) + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) SubClassOf [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [antiatherogenic agent](http://purl.obolibrary.org/obo/CHEBI_50855) + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [antineoplastic agent](http://purl.obolibrary.org/obo/CHEBI_35610) + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) SubClassOf [peptide hormone](http://purl.obolibrary.org/obo/CHEBI_25905) + +- [ghrelin](http://purl.obolibrary.org/obo/CHEBI_75431) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + + + +### glial blood brain barrier `http://purl.obolibrary.org/obo/UBERON_0000202` +#### Removed +- [glial blood brain barrier](http://purl.obolibrary.org/obo/UBERON_0000202) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007091" + + + +### glucagon `http://purl.obolibrary.org/obo/CHEBI_5391` +#### Removed +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22454291" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:5391" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:9007-92-5" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:13191924" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22334714" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "MASNOZXLGMXCHN-ZLPAWPGGSA-N" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glucagon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [mass](http://purl.obolibrary.org/obo/chebi/mass) "3482.74700" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22438981" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:2994" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22214853" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Glucagon" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "3480.61570" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D00116" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C153H225N43O49S" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22227186" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HSQGTFTSDYSKYLDSRRAQDFVQWLMNT" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132(225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100(57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112(156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,30-32,41-63,66-70,154-155H2,1-11H3,(H2,156,206)(H2,157,207)(H2,158,208)(H2,159,209)(H,164,169)(H,168,219)(H,170,220)(H,171,217)(H,172,221)(H,173,238)(H,174,239)(H,175,237)(H,176,226)(H,177,241)(H,178,228)(H,179,230)(H,180,222)(H,181,232)(H,182,231)(H,183,224)(H,184,225)(H,185,223)(H,186,227)(H,187,240)(H,188,242)(H,189,218)(H,190,229)(H,191,233)(H,192,243)(H,193,210)(H,194,234)(H,195,235)(H,196,236)(H,211,212)(H,213,214)(H,215,216)(H,244,245)(H4,160,161,165)(H4,162,163,166)/t75-,76+,77+,78+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-/m0/s1" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01501" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glucagonum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22014161" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22286080" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:16941-32-5" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [label](http://www.w3.org/2000/01/rdf-schema#label) "glucagon" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22318544" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB00040" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Glucagon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence." + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22399501" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22154917" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22294753" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glucagone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21940356" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22166985" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22167521" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:9007-92-5" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [glucagon](http://purl.obolibrary.org/obo/CHEBI_5391) SubClassOf [peptide hormone](http://purl.obolibrary.org/obo/CHEBI_25905) + + + +### glucan `http://purl.obolibrary.org/obo/CHEBI_37163` +#### Removed +- [glucan](http://purl.obolibrary.org/obo/CHEBI_37163) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5392" + +- [glucan](http://purl.obolibrary.org/obo/CHEBI_37163) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C12H22O11(C6H10O5)n" + +- [glucan](http://purl.obolibrary.org/obo/CHEBI_37163) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A polysaccharide composed of glucose residues." + +- [glucan](http://purl.obolibrary.org/obo/CHEBI_37163) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glucan" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [glucan](http://purl.obolibrary.org/obo/CHEBI_37163) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:37163" + +- [glucan](http://purl.obolibrary.org/obo/CHEBI_37163) [label](http://www.w3.org/2000/01/rdf-schema#label) "glucan" + +- [glucan](http://purl.obolibrary.org/obo/CHEBI_37163) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24255" + +- [glucan](http://purl.obolibrary.org/obo/CHEBI_37163) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glucan](http://purl.obolibrary.org/obo/CHEBI_37163) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Glucan" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [glucan](http://purl.obolibrary.org/obo/CHEBI_37163) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:9037-91-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [glucan](http://purl.obolibrary.org/obo/CHEBI_37163) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01379" + +- [glucan](http://purl.obolibrary.org/obo/CHEBI_37163) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glucans" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glucan](http://purl.obolibrary.org/obo/CHEBI_37163) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glucan](http://purl.obolibrary.org/obo/CHEBI_37163) SubClassOf [homopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37164) + + + +### glucan biosynthetic process `http://purl.obolibrary.org/obo/GO_0009250` +#### Removed +- [glucan biosynthetic process](http://purl.obolibrary.org/obo/GO_0009250) SubClassOf [cellular glucan metabolic process](http://purl.obolibrary.org/obo/GO_0006073) + +- [glucan biosynthetic process](http://purl.obolibrary.org/obo/GO_0009250) SubClassOf [cellular polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0033692) + +#### Added +- [glucan biosynthetic process](http://purl.obolibrary.org/obo/GO_0009250) SubClassOf [glucan metabolic process](http://purl.obolibrary.org/obo/GO_0044042) + +- [glucan biosynthetic process](http://purl.obolibrary.org/obo/GO_0009250) SubClassOf [polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0000271) + + +### glucan catabolic process `http://purl.obolibrary.org/obo/GO_0009251` +#### Removed +- [glucan catabolic process](http://purl.obolibrary.org/obo/GO_0009251) SubClassOf [polysaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0000272) + +#### Added +- [glucan catabolic process](http://purl.obolibrary.org/obo/GO_0009251) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### glucan metabolic process `http://purl.obolibrary.org/obo/GO_0044042` +#### Removed +- [glucan metabolic process](http://purl.obolibrary.org/obo/GO_0044042) SubClassOf [polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005976) + +#### Added +- [glucan metabolic process](http://purl.obolibrary.org/obo/GO_0044042) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### glucocorticoid `http://purl.obolibrary.org/obo/CHEBI_24261` +#### Removed +- [glucocorticoid](http://purl.obolibrary.org/obo/CHEBI_24261) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glucocorticoids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glucocorticoid](http://purl.obolibrary.org/obo/CHEBI_24261) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood." + +- [glucocorticoid](http://purl.obolibrary.org/obo/CHEBI_24261) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glucocorticoid](http://purl.obolibrary.org/obo/CHEBI_24261) [label](http://www.w3.org/2000/01/rdf-schema#label) "glucocorticoid" + +- [glucocorticoid](http://purl.obolibrary.org/obo/CHEBI_24261) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glucocorticoid](http://purl.obolibrary.org/obo/CHEBI_24261) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24261" + +- [glucocorticoid](http://purl.obolibrary.org/obo/CHEBI_24261) SubClassOf [corticosteroid hormone](http://purl.obolibrary.org/obo/CHEBI_36699) + + + +### glucocorticoid biosynthetic process `http://purl.obolibrary.org/obo/GO_0006704` +#### Removed +- [glucocorticoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006704) SubClassOf [steroid hormone biosynthetic process](http://purl.obolibrary.org/obo/GO_0120178) + +#### Added +- [glucocorticoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006704) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### glucocorticoid catabolic process `http://purl.obolibrary.org/obo/GO_0006713` +#### Removed +- [glucocorticoid catabolic process](http://purl.obolibrary.org/obo/GO_0006713) SubClassOf [steroid catabolic process](http://purl.obolibrary.org/obo/GO_0006706) + +#### Added +- [glucocorticoid catabolic process](http://purl.obolibrary.org/obo/GO_0006713) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### gluconeogenesis `http://purl.obolibrary.org/obo/GO_0006094` +#### Removed +- [gluconeogenesis](http://purl.obolibrary.org/obo/GO_0006094) SubClassOf [hexose biosynthetic process](http://purl.obolibrary.org/obo/GO_0019319) + +#### Added +- [gluconeogenesis](http://purl.obolibrary.org/obo/GO_0006094) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### glucose `http://purl.obolibrary.org/obo/CHEBI_17234` +#### Removed +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glc" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "JCBN" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Glucose" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "180.06339" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Glucose" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14313" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glukose" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "DL-glucose" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [mass](http://purl.obolibrary.org/obo/chebi/mass) "180.15588" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:33929" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24277" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glucose" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:50-99-7" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [label](http://www.w3.org/2000/01/rdf-schema#label) "glucose" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00293" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An aldohexose used as a source of energy and metabolic intermediate." + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:17234" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C6H12O6" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5418" + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "gluco-hexose" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) SubClassOf [aldohexose](http://purl.obolibrary.org/obo/CHEBI_33917) + +- [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [fundamental metabolite](http://purl.obolibrary.org/obo/CHEBI_78675) + + + +### glucose binding `http://purl.obolibrary.org/obo/GO_0005536` +#### Removed +- [glucose binding](http://purl.obolibrary.org/obo/GO_0005536) SubClassOf [monosaccharide binding](http://purl.obolibrary.org/obo/GO_0048029) + +#### Added +- [glucose binding](http://purl.obolibrary.org/obo/GO_0005536) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### glucose catabolic process `http://purl.obolibrary.org/obo/GO_0006007` +#### Removed +- [glucose catabolic process](http://purl.obolibrary.org/obo/GO_0006007) SubClassOf [hexose catabolic process](http://purl.obolibrary.org/obo/GO_0019320) + +#### Added +- [glucose catabolic process](http://purl.obolibrary.org/obo/GO_0006007) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### glucose catabolic process to butyrate `http://purl.obolibrary.org/obo/GO_0030645` +#### Removed +- [glucose catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0030645) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "butyrate fermentation" + +- [glucose catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0030645) [label](http://www.w3.org/2000/01/rdf-schema#label) "glucose catabolic process to butyrate" + +- [glucose catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0030645) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0030645" + +- [glucose catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0030645) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [glucose catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0030645) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The anaerobic chemical reactions and pathways resulting in the breakdown of glucose, with the production of acetic acid, butyric acid, carbon dioxide (CO2), and dihydrogen; effected by some saccharolytic species of Clostridium, e.g. C. butyricum." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [glucose catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0030645) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glucose fermentation to butyrate" + +- Class: [glucose catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0030645) + +- [glucose catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0030645) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968)) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [glucose](http://purl.obolibrary.org/obo/CHEBI_17234)) + +- [glucose catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0030645) SubClassOf [fermentation](http://purl.obolibrary.org/obo/GO_0006113) + +- [glucose catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0030645) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) + +- [glucose catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0030645) SubClassOf [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) + +- [glucose catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0030645) SubClassOf [glucose catabolic process](http://purl.obolibrary.org/obo/GO_0006007) + + + +### glucose homeostasis `http://purl.obolibrary.org/obo/GO_0042593` +#### Removed +- [glucose homeostasis](http://purl.obolibrary.org/obo/GO_0042593) SubClassOf [carbohydrate homeostasis](http://purl.obolibrary.org/obo/GO_0033500) + +#### Added +- [glucose homeostasis](http://purl.obolibrary.org/obo/GO_0042593) SubClassOf [chemical homeostasis](http://purl.obolibrary.org/obo/GO_0048878) + + +### glucose transmembrane transport `http://purl.obolibrary.org/obo/GO_1904659` +#### Removed +- [glucose transmembrane transport](http://purl.obolibrary.org/obo/GO_1904659) SubClassOf [hexose transmembrane transport](http://purl.obolibrary.org/obo/GO_0008645) + +#### Added +- [glucose transmembrane transport](http://purl.obolibrary.org/obo/GO_1904659) SubClassOf [transmembrane transport](http://purl.obolibrary.org/obo/GO_0055085) + + +### glucose transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0005355` +#### Removed +- [glucose transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005355) SubClassOf [hexose transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015149) + +#### Added +- [glucose transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005355) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + +### glutamate binding `http://purl.obolibrary.org/obo/GO_0016595` +#### Removed +- [glutamate binding](http://purl.obolibrary.org/obo/GO_0016595) SubClassOf [carboxylic acid binding](http://purl.obolibrary.org/obo/GO_0031406) + +#### Added +- [glutamate binding](http://purl.obolibrary.org/obo/GO_0016595) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### glutamate biosynthetic process `http://purl.obolibrary.org/obo/GO_0006537` +#### Removed +- [glutamate biosynthetic process](http://purl.obolibrary.org/obo/GO_0006537) SubClassOf [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) + + + +### glutamate catabolic process `http://purl.obolibrary.org/obo/GO_0006538` +#### Removed +- [glutamate catabolic process](http://purl.obolibrary.org/obo/GO_0006538) SubClassOf [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) + + + +### glutamate catabolic process to butyrate `http://purl.obolibrary.org/obo/GO_0033508` +#### Removed +- [glutamate catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0033508) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including butyrate." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:PWY-5087" + +- [glutamate catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0033508) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glutamate degradation to butyrate" + +- [glutamate catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0033508) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [glutamate catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0033508) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glutamate breakdown to butyrate" + +- [glutamate catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0033508) [label](http://www.w3.org/2000/01/rdf-schema#label) "glutamate catabolic process to butyrate" + +- [glutamate catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0033508) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0033508" + +- [glutamate catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0033508) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:PWY-5087" + +- Class: [glutamate catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0033508) + +- [glutamate catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0033508) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968)) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321)) + +- [glutamate catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0033508) SubClassOf [butyrate metabolic process](http://purl.obolibrary.org/obo/GO_0019605) + +- [glutamate catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0033508) SubClassOf [glutamate catabolic process](http://purl.obolibrary.org/obo/GO_0006538) + +- [glutamate catabolic process to butyrate](http://purl.obolibrary.org/obo/GO_0033508) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) + + + +### glutamate secretion `http://purl.obolibrary.org/obo/GO_0014047` +#### Removed +- [glutamate secretion](http://purl.obolibrary.org/obo/GO_0014047) SubClassOf [carboxylic acid transport](http://purl.obolibrary.org/obo/GO_0046942) + + + +### glutamate secretion, neurotransmission `http://purl.obolibrary.org/obo/GO_0061535` + +#### Added +- [glutamate secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061535) EquivalentTo [neurotransmitter secretion](http://purl.obolibrary.org/obo/GO_0007269) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_29985](http://purl.obolibrary.org/obo/CHEBI_29985)) + +- [glutamate secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061535) SubClassOf [L-glutamate import](http://purl.obolibrary.org/obo/GO_0051938) + + +### glutamate(1-) `http://purl.obolibrary.org/obo/CHEBI_14321` +#### Removed +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:14321" + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glutamate(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "JCBN" + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:327908" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "WHUUTDBJXJRKMK-UHFFFAOYSA-M" + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [mass](http://purl.obolibrary.org/obo/chebi/mass) "146.12136" + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glutamic acid monoanion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "JCBN" + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1" + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogen glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [label](http://www.w3.org/2000/01/rdf-schema#label) "glutamate(1-)" + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An alpha-amino-acid anion that is the conjugate base of glutamic acid, having anionic carboxy groups and a cationic amino group" + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "2-ammoniopentanedioate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C5H8NO4" + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "146.04588" + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[NH3+]C(CCC([O-])=O)C([O-])=O" + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [fundamental metabolite](http://purl.obolibrary.org/obo/CHEBI_78675) + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) SubClassOf [alpha-amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_33558) + +- [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) + + + +### glutamate(2-) `http://purl.obolibrary.org/obo/CHEBI_29987` +#### Removed +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-2" + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glutamate(2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "JCBN" + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "NC(CCC([O-])=O)C([O-])=O" + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [mass](http://purl.obolibrary.org/obo/chebi/mass) "145.11342" + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:29987" + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-2" + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:327903" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:4134100" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "2-aminopentanedioate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:4134100" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C5H7NO4" + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [label](http://www.w3.org/2000/01/rdf-schema#label) "glutamate(2-)" + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A dicarboxylic acid dianion that is the conjugate base of glutamate(1-)." + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "WHUUTDBJXJRKMK-UHFFFAOYSA-L" + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "145.03860" + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glutamic acid dianion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "JCBN" + +- Class: [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [fundamental metabolite](http://purl.obolibrary.org/obo/CHEBI_78675) + +- [glutamate(2-)](http://purl.obolibrary.org/obo/CHEBI_29987) SubClassOf [dicarboxylic acid dianion](http://purl.obolibrary.org/obo/CHEBI_28965) + + + +### glutamic acid `http://purl.obolibrary.org/obo/CHEBI_18237` +#### Removed +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15739367" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24314" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24984001" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [label](http://www.w3.org/2000/01/rdf-schema#label) "glutamic acid" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glutaminsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Glutamic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An alpha-amino acid that has formula C5H9NO4." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "WHUUTDBJXJRKMK-UHFFFAOYSA-N" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:1723799" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "NC(CCC(O)=O)C(O)=O" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24616376" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [mass](http://purl.obolibrary.org/obo/chebi/mass) "147.12930" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "DL-Glutaminic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An alpha-amino acid that is glutaric acid bearing a single amino substituent at position 2." + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "DL-Glutamic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_DRUG" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Glutamic_acid" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glutaminic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "C5H9NO4" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [FORMULA](http://purl.obolibrary.org/obo/fbbt#FORMULA) + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C5H9NO4" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "2-aminopentanedioic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:1723799" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glutaminsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "2-Aminoglutaric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17190852" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:617-65-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D04341" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NC(CCC(O)=O)C(O)=O" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [SMILES](http://purl.obolibrary.org/obo/fbbt#SMILES) + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glutaminic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glutamic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "InChIKey=WHUUTDBJXJRKMK-UHFFFAOYSA-N" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [InChIKey](http://purl.obolibrary.org/obo/fbbt#InChIKey) + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00302" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "2-Aminoglutaric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "E" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "2-aminopentanedioic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:18237" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00001358" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5431" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glu" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "147.05316" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00019577" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [InChI](http://purl.obolibrary.org/obo/fbbt#InChI) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:101971" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glutamic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:617-65-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:617-65-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- Class: [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [2-carboxyethyl group](http://purl.obolibrary.org/obo/CHEBI_50329) + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) SubClassOf [alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_33704) + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) SubClassOf [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) + +- [glutamic acid](http://purl.obolibrary.org/obo/CHEBI_18237) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [fundamental metabolite](http://purl.obolibrary.org/obo/CHEBI_78675) + + + +### glutamine family amino acid `http://purl.obolibrary.org/obo/CHEBI_24318` +#### Removed +- [glutamine family amino acid](http://purl.obolibrary.org/obo/CHEBI_24318) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glutamine family amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glutamine family amino acid](http://purl.obolibrary.org/obo/CHEBI_24318) [label](http://www.w3.org/2000/01/rdf-schema#label) "glutamine family amino acid" + +- [glutamine family amino acid](http://purl.obolibrary.org/obo/CHEBI_24318) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24318" + +- [glutamine family amino acid](http://purl.obolibrary.org/obo/CHEBI_24318) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glutamine family amino acid](http://purl.obolibrary.org/obo/CHEBI_24318) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An L-alpha-amino acid which is L-glutamic acid or any of the essential amino acids biosynthesised from it (glutamine, proline and arginine). A closed class." + +- [glutamine family amino acid](http://purl.obolibrary.org/obo/CHEBI_24318) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glutamine family amino acid](http://purl.obolibrary.org/obo/CHEBI_24318) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20716061" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glutamine family amino acid](http://purl.obolibrary.org/obo/CHEBI_24318) SubClassOf [proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83813) + +- [glutamine family amino acid](http://purl.obolibrary.org/obo/CHEBI_24318) SubClassOf [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) + + + +### glutamine family amino acid biosynthetic process `http://purl.obolibrary.org/obo/GO_0009084` +#### Removed +- [glutamine family amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009084) SubClassOf [organonitrogen compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901566) + +- [glutamine family amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009084) SubClassOf [organic acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016053) + +#### Added +- [glutamine family amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009084) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### glutamine family amino acid catabolic process `http://purl.obolibrary.org/obo/GO_0009065` +#### Removed +- [glutamine family amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009065) SubClassOf [organic acid catabolic process](http://purl.obolibrary.org/obo/GO_0016054) + +- [glutamine family amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009065) SubClassOf [organonitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_1901565) + +#### Added +- [glutamine family amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009065) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### glycan `http://purl.obolibrary.org/obo/CHEBI_167559` +#### Removed +- [glycan](http://purl.obolibrary.org/obo/CHEBI_167559) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glycans" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glycan](http://purl.obolibrary.org/obo/CHEBI_167559) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glycan](http://purl.obolibrary.org/obo/CHEBI_167559) [label](http://www.w3.org/2000/01/rdf-schema#label) "glycan" + +- [glycan](http://purl.obolibrary.org/obo/CHEBI_167559) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001." + +- [glycan](http://purl.obolibrary.org/obo/CHEBI_167559) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:167559" + +- [glycan](http://purl.obolibrary.org/obo/CHEBI_167559) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [glycan](http://purl.obolibrary.org/obo/CHEBI_167559) + +- [glycan](http://purl.obolibrary.org/obo/CHEBI_167559) SubClassOf [carbohydrates and carbohydrate derivatives](http://purl.obolibrary.org/obo/CHEBI_78616) + + + +### glycinate `http://purl.obolibrary.org/obo/CHEBI_32508` +#### Removed +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glycine anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "JCBN" + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gly(-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [mass](http://purl.obolibrary.org/obo/chebi/mass) "74.05870" + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "H2N-CH2-COO(-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glycinate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:81890" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:1852023" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "NCC([O-])=O" + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)/p-1" + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aminoacetate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "DHMQDGOQFOQNFH-UHFFFAOYSA-M" + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2H4NO2" + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:32508" + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UM-BBD_compID:c0559" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "UM-BBD" + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [label](http://www.w3.org/2000/01/rdf-schema#label) "glycinate" + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An alpha-amino-acid anion that is the conjugate base of glycine, arising from deprotonation of the carboxy group." + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:1852023" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "74.02475" + +- Class: [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [fundamental metabolite](http://purl.obolibrary.org/obo/CHEBI_78675) + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) + +- [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) SubClassOf [alpha-amino-acid anion](http://purl.obolibrary.org/obo/CHEBI_33558) + + + +### glycine `http://purl.obolibrary.org/obo/CHEBI_15428` +#### Removed +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Glycine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Gly" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5460" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16417482" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "GLYCINE" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000123" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12754315" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glyzin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11019925" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:GLY" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22264337" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22401276" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12631515" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18816054" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17383967" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "75.03203" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16998855" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18593588" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17582620" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:1319" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aminoethanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [label](http://www.w3.org/2000/01/rdf-schema#label) "glycine" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:42964" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22234938" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:56-40-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:56-40-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:GLY" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "H2N-CH2-COOH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19544666" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:635782" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glycin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glykokoll" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10930630" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14344" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11542461" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16664855" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12770151" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15710237" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19449910" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aminoacetic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16901953" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16444815" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16151895" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "YMDB:YMDB00016" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19738917" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18396796" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:10792" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D00011" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Glycine" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:56-40-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22293292" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glycine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19916621" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ECMDB:ECMDB00123" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11806864" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19924257" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00037" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2H5NO2" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22079563" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:635782" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15388434" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19526731" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "NCC(O)=O" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18440992" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19120667" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11174716" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16214212" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22044190" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Aminoacetic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The simplest (and the only achiral) proteinogenic amino acid, with a hydrogen atom as its side chain." + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "DHMQDGOQFOQNFH-UHFFFAOYSA-N" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glycocoll" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Leimzucker" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:1808" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24368" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18840508" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB00145" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Hgly" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aminoethanoic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "JCBN" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:15428" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16918424" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "G" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [mass](http://purl.obolibrary.org/obo/chebi/mass) "75.06664" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19028609" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00001361" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12921899" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17970719" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17154252" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16105183" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18079355" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21751272" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16986325" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Aminoessigsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15331688" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22434786" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- Class: [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor](http://purl.obolibrary.org/obo/CHEBI_64570) + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [nutraceutical](http://purl.obolibrary.org/obo/CHEBI_50733) + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) SubClassOf [serine family amino acid](http://purl.obolibrary.org/obo/CHEBI_26650) + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) SubClassOf [is_tautomer_of](http://purl.obolibrary.org/obo/chebi#is_tautomer_of) some [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [hepatoprotective agent](http://purl.obolibrary.org/obo/CHEBI_62868) + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [fundamental metabolite](http://purl.obolibrary.org/obo/CHEBI_78675) + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [NMDA receptor agonist](http://purl.obolibrary.org/obo/CHEBI_64571) + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [neurotransmitter](http://purl.obolibrary.org/obo/CHEBI_25512) + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [micronutrient](http://purl.obolibrary.org/obo/CHEBI_27027) + +- [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [glycinate](http://purl.obolibrary.org/obo/CHEBI_32508) + + + +### glycine secretion, neurotransmission `http://purl.obolibrary.org/obo/GO_0061537` + +#### Added +- [glycine secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061537) EquivalentTo [neurotransmitter secretion](http://purl.obolibrary.org/obo/GO_0007269) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305)) + + +### glycine zwitterion `http://purl.obolibrary.org/obo/CHEBI_57305` +#### Removed +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "2-azaniumylacetate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:57305" + +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2H5NO2" + +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:GLY" + +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "DHMQDGOQFOQNFH-UHFFFAOYSA-N" + +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of glycine." + +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:1807" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)" + +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glycine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "75.03203" + +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) [mass](http://purl.obolibrary.org/obo/chebi/mass) "75.06660" + +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) [label](http://www.w3.org/2000/01/rdf-schema#label) "glycine zwitterion" + +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[NH3+]CC([O-])=O" + +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) SubClassOf [amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_35238) + +- [glycine zwitterion](http://purl.obolibrary.org/obo/CHEBI_57305) SubClassOf [is_tautomer_of](http://purl.obolibrary.org/obo/chebi#is_tautomer_of) some [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) + + + +### glycinium `http://purl.obolibrary.org/obo/CHEBI_32507` +#### Removed +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[NH3+]CC(O)=O" + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2H6NO2" + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carboxymethanaminium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "76.03930" + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+1" + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NH3(+)-CH2-COOH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:32507" + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "H2gly(+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:323509" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "DHMQDGOQFOQNFH-UHFFFAOYSA-O" + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [mass](http://purl.obolibrary.org/obo/chebi/mass) "76.07458" + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glycine cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "JCBN" + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [label](http://www.w3.org/2000/01/rdf-schema#label) "glycinium" + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)/p+1" + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glycinium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An alpha-amino-acid cation that is the conjugate acid of glycine, arising from protonation of the amino." + +- Class: [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [fundamental metabolite](http://purl.obolibrary.org/obo/CHEBI_78675) + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) SubClassOf [alpha-amino-acid cation](http://purl.obolibrary.org/obo/CHEBI_33719) + +- [glycinium](http://purl.obolibrary.org/obo/CHEBI_32507) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [glycine](http://purl.obolibrary.org/obo/CHEBI_15428) + + + +### glycogen `http://purl.obolibrary.org/obo/CHEBI_28087` +#### Removed +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some cumulative alpha(1->6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues." + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000757" + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "WURCS=2.0/1,4,3/[a2122h-1a_1-5]/1-1-1-1/a4-b1_b4-c1_b6-d1" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GlyTouCan" + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "animal starch" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "liver starch" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GlyTouCan:G99991IU" + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GlyGen:G99991IU" + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:9005-79-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24379" + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5466" + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:CPD0-971" + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:28087" + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Glycogen" + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:9005-79-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Glycogen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00182" + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) [label](http://www.w3.org/2000/01/rdf-schema#label) "glycogen" + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) SubClassOf [glycogens](http://purl.obolibrary.org/obo/CHEBI_24384) + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) + +- [glycogen](http://purl.obolibrary.org/obo/CHEBI_28087) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) + + + +### glycogen binding `http://purl.obolibrary.org/obo/GO_2001069` +#### Removed +- [glycogen binding](http://purl.obolibrary.org/obo/GO_2001069) SubClassOf [polysaccharide binding](http://purl.obolibrary.org/obo/GO_0030247) + +#### Added +- [glycogen binding](http://purl.obolibrary.org/obo/GO_2001069) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### glycogen catabolic process `http://purl.obolibrary.org/obo/GO_0005980` +#### Removed +- [glycogen catabolic process](http://purl.obolibrary.org/obo/GO_0005980) SubClassOf [cellular polysaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0044247) + +- [glycogen catabolic process](http://purl.obolibrary.org/obo/GO_0005980) SubClassOf [glucan catabolic process](http://purl.obolibrary.org/obo/GO_0009251) + +#### Added +- [glycogen catabolic process](http://purl.obolibrary.org/obo/GO_0005980) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### glycogen metabolic process `http://purl.obolibrary.org/obo/GO_0005977` +#### Removed +- [glycogen metabolic process](http://purl.obolibrary.org/obo/GO_0005977) SubClassOf [cellular glucan metabolic process](http://purl.obolibrary.org/obo/GO_0006073) + +#### Added +- [glycogen metabolic process](http://purl.obolibrary.org/obo/GO_0005977) SubClassOf [carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0005975) + +- [glycogen metabolic process](http://purl.obolibrary.org/obo/GO_0005977) SubClassOf [glucan metabolic process](http://purl.obolibrary.org/obo/GO_0044042) + + +### glycogens `http://purl.obolibrary.org/obo/CHEBI_24384` +#### Removed +- [glycogens](http://purl.obolibrary.org/obo/CHEBI_24384) [label](http://www.w3.org/2000/01/rdf-schema#label) "glycogens" + +- [glycogens](http://purl.obolibrary.org/obo/CHEBI_24384) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glycogens](http://purl.obolibrary.org/obo/CHEBI_24384) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glycogens](http://purl.obolibrary.org/obo/CHEBI_24384) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24384" + +- Class: [glycogens](http://purl.obolibrary.org/obo/CHEBI_24384) + +- [glycogens](http://purl.obolibrary.org/obo/CHEBI_24384) SubClassOf [glucan](http://purl.obolibrary.org/obo/CHEBI_37163) + + + +### glycolipid `http://purl.obolibrary.org/obo/CHEBI_33563` +#### Removed +- [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C05005" + +- [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) [label](http://www.w3.org/2000/01/rdf-schema#label) "glycolipid" + +- [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any member of class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar part acylated by one or more fatty acids and the glycerol part may be absent." + +- [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33563" + +- [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glycolipids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24393" + +- [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Glycolipid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5476" + +- [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Glycolipids" + +- Class: [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) + +- [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) SubClassOf [liposaccharide](http://purl.obolibrary.org/obo/CHEBI_35740) + + + +### glycolipid binding `http://purl.obolibrary.org/obo/GO_0051861` +#### Removed +- [glycolipid binding](http://purl.obolibrary.org/obo/GO_0051861) [label](http://www.w3.org/2000/01/rdf-schema#label) "glycolipid binding" + +- [glycolipid binding](http://purl.obolibrary.org/obo/GO_0051861) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0051861" + +- [glycolipid binding](http://purl.obolibrary.org/obo/GO_0051861) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19635802" + +- [glycolipid binding](http://purl.obolibrary.org/obo/GO_0051861) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- Class: [glycolipid binding](http://purl.obolibrary.org/obo/GO_0051861) + +- [glycolipid binding](http://purl.obolibrary.org/obo/GO_0051861) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563)) + +- [glycolipid binding](http://purl.obolibrary.org/obo/GO_0051861) SubClassOf [carbohydrate derivative binding](http://purl.obolibrary.org/obo/GO_0097367) + +- [glycolipid binding](http://purl.obolibrary.org/obo/GO_0051861) SubClassOf [lipid binding](http://purl.obolibrary.org/obo/GO_0008289) + +- [glycolipid binding](http://purl.obolibrary.org/obo/GO_0051861) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) + + + +### glycolipid biosynthetic process `http://purl.obolibrary.org/obo/GO_0009247` +#### Removed +- [glycolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009247) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glycolipid synthesis" + +- [glycolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009247) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glycolipid formation" + +- [glycolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009247) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [glycolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009247) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:PWY-401" + +- [glycolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009247) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glycolipid biosynthesis" + +- [glycolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009247) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glycolipid anabolism" + +- [glycolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009247) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [glycolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009247) [label](http://www.w3.org/2000/01/rdf-schema#label) "glycolipid biosynthetic process" + +- [glycolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009247) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0009247" + +- Class: [glycolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009247) + +- [glycolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009247) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563)) + +- [glycolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009247) SubClassOf [glycolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006664) + +- [glycolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009247) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) + +- [glycolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009247) SubClassOf [carbohydrate derivative biosynthetic process](http://purl.obolibrary.org/obo/GO_1901137) + +- [glycolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009247) SubClassOf [membrane lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046467) + + + +### glycolipid catabolic process `http://purl.obolibrary.org/obo/GO_0019377` +#### Removed +- [glycolipid catabolic process](http://purl.obolibrary.org/obo/GO_0019377) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glycolipid breakdown" + +- [glycolipid catabolic process](http://purl.obolibrary.org/obo/GO_0019377) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glycolipid degradation" + +- [glycolipid catabolic process](http://purl.obolibrary.org/obo/GO_0019377) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glycolipid catabolism" + +- [glycolipid catabolic process](http://purl.obolibrary.org/obo/GO_0019377) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [glycolipid catabolic process](http://purl.obolibrary.org/obo/GO_0019377) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0019377" + +- [glycolipid catabolic process](http://purl.obolibrary.org/obo/GO_0019377) [label](http://www.w3.org/2000/01/rdf-schema#label) "glycolipid catabolic process" + +- [glycolipid catabolic process](http://purl.obolibrary.org/obo/GO_0019377) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [glycolipid catabolic process](http://purl.obolibrary.org/obo/GO_0019377) + +- [glycolipid catabolic process](http://purl.obolibrary.org/obo/GO_0019377) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563)) + +- [glycolipid catabolic process](http://purl.obolibrary.org/obo/GO_0019377) SubClassOf [glycolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006664) + +- [glycolipid catabolic process](http://purl.obolibrary.org/obo/GO_0019377) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) + +- [glycolipid catabolic process](http://purl.obolibrary.org/obo/GO_0019377) SubClassOf [membrane lipid catabolic process](http://purl.obolibrary.org/obo/GO_0046466) + +- [glycolipid catabolic process](http://purl.obolibrary.org/obo/GO_0019377) SubClassOf [carbohydrate derivative catabolic process](http://purl.obolibrary.org/obo/GO_1901136) + + + +### glycolipid metabolic process `http://purl.obolibrary.org/obo/GO_0006664` +#### Removed +- [glycolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006664) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [glycolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006664) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glycolipid metabolism" + +- [glycolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006664) [label](http://www.w3.org/2000/01/rdf-schema#label) "glycolipid metabolic process" + +- [glycolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006664) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198547684" + +- [glycolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006664) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006664" + +- Class: [glycolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006664) + +- [glycolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006664) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563)) + +- [glycolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006664) SubClassOf [membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_0006643) + +- [glycolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006664) SubClassOf [liposaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903509) + +- [glycolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006664) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) + + + +### glycolipid transport `http://purl.obolibrary.org/obo/GO_0046836` +#### Removed +- [glycolipid transport](http://purl.obolibrary.org/obo/GO_0046836) [label](http://www.w3.org/2000/01/rdf-schema#label) "glycolipid transport" + +- [glycolipid transport](http://purl.obolibrary.org/obo/GO_0046836) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [glycolipid transport](http://purl.obolibrary.org/obo/GO_0046836) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [glycolipid transport](http://purl.obolibrary.org/obo/GO_0046836) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046836" + +- Class: [glycolipid transport](http://purl.obolibrary.org/obo/GO_0046836) + +- [glycolipid transport](http://purl.obolibrary.org/obo/GO_0046836) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563)) + +- [glycolipid transport](http://purl.obolibrary.org/obo/GO_0046836) SubClassOf [lipid transport](http://purl.obolibrary.org/obo/GO_0006869) + +- [glycolipid transport](http://purl.obolibrary.org/obo/GO_0046836) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) + +- [glycolipid transport](http://purl.obolibrary.org/obo/GO_0046836) SubClassOf [carbohydrate derivative transport](http://purl.obolibrary.org/obo/GO_1901264) + + + +### glycoprotein `http://purl.obolibrary.org/obo/CHEBI_17089` +#### Removed +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5481" + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:17089" + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glycoproteines" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a glycoprotein" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glicoproteina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glicoproteinas" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glykoproteine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14349" + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glycoproteine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00326" + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [label](http://www.w3.org/2000/01/rdf-schema#label) "glycoprotein" + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glykoprotein" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A compound in which a carbohydrate component is covalently bound to a protein component." + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glycoproteins" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Glycoprotein" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5493" + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) SubClassOf [carbohydrate derivative](http://purl.obolibrary.org/obo/CHEBI_63299) + +- [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) SubClassOf [conjugated protein](http://purl.obolibrary.org/obo/CHEBI_33837) + + + +### glycoprotein biosynthetic process `http://purl.obolibrary.org/obo/GO_0009101` +#### Removed +- [glycoprotein biosynthetic process](http://purl.obolibrary.org/obo/GO_0009101) SubClassOf [carbohydrate derivative biosynthetic process](http://purl.obolibrary.org/obo/GO_1901137) + +- [glycoprotein biosynthetic process](http://purl.obolibrary.org/obo/GO_0009101) SubClassOf [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) + +- [glycoprotein biosynthetic process](http://purl.obolibrary.org/obo/GO_0009101) SubClassOf [organonitrogen compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901566) + +#### Added +- [glycoprotein biosynthetic process](http://purl.obolibrary.org/obo/GO_0009101) SubClassOf [macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0009059) + + +### glycoprotein catabolic process `http://purl.obolibrary.org/obo/GO_0006516` +#### Removed +- [glycoprotein catabolic process](http://purl.obolibrary.org/obo/GO_0006516) SubClassOf [protein catabolic process](http://purl.obolibrary.org/obo/GO_0030163) + +- [glycoprotein catabolic process](http://purl.obolibrary.org/obo/GO_0006516) SubClassOf [carbohydrate derivative catabolic process](http://purl.obolibrary.org/obo/GO_1901136) + +- [glycoprotein catabolic process](http://purl.obolibrary.org/obo/GO_0006516) SubClassOf [cellular macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0044265) + +#### Added +- [glycoprotein catabolic process](http://purl.obolibrary.org/obo/GO_0006516) SubClassOf [macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0009057) + + +### glycoprotein metabolic process `http://purl.obolibrary.org/obo/GO_0009100` +#### Removed +- [glycoprotein metabolic process](http://purl.obolibrary.org/obo/GO_0009100) SubClassOf [carbohydrate derivative metabolic process](http://purl.obolibrary.org/obo/GO_1901135) + +- [glycoprotein metabolic process](http://purl.obolibrary.org/obo/GO_0009100) SubClassOf [cellular macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0044260) + +- [glycoprotein metabolic process](http://purl.obolibrary.org/obo/GO_0009100) SubClassOf [protein metabolic process](http://purl.obolibrary.org/obo/GO_0019538) + +#### Added +- [glycoprotein metabolic process](http://purl.obolibrary.org/obo/GO_0009100) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### glycoprotein transport `http://purl.obolibrary.org/obo/GO_0034436` +#### Removed +- [glycoprotein transport](http://purl.obolibrary.org/obo/GO_0034436) SubClassOf [protein transport](http://purl.obolibrary.org/obo/GO_0015031) + +- [glycoprotein transport](http://purl.obolibrary.org/obo/GO_0034436) SubClassOf [carbohydrate derivative transport](http://purl.obolibrary.org/obo/GO_1901264) + +#### Added +- [glycoprotein transport](http://purl.obolibrary.org/obo/GO_0034436) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### glycosaminoglycan `http://purl.obolibrary.org/obo/CHEBI_18085` +#### Removed +- [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any polysaccharide containing a substantial proportion of aminomonosaccharide residues." + +- [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C02545" + +- [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24398" + +- [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glykosaminoglykan" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) [label](http://www.w3.org/2000/01/rdf-schema#label) "glycosaminoglycan" + +- [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Glycosaminoglycan" + +- [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glycosaminoglycan" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Glycosaminoglycan" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glycosaminoglycans" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5495" + +- [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glicosaminoglicano" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:18085" + +- [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14361" + +- [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glycosaminoglycane" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) SubClassOf [aminoglycan](http://purl.obolibrary.org/obo/CHEBI_22506) + + + +### glycosaminoglycan biosynthetic process `http://purl.obolibrary.org/obo/GO_0006024` +#### Removed +- [glycosaminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006024) SubClassOf [aminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006023) + +#### Added +- [glycosaminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006024) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### glycosaminoglycan catabolic process `http://purl.obolibrary.org/obo/GO_0006027` +#### Removed +- [glycosaminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006027) SubClassOf [aminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006026) + +#### Added +- [glycosaminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006027) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### glycosaminoglycan metabolic process `http://purl.obolibrary.org/obo/GO_0030203` +#### Removed +- [glycosaminoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0030203) SubClassOf [aminoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0006022) + +#### Added +- [glycosaminoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0030203) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### glycosphingolipid `http://purl.obolibrary.org/obo/CHEBI_24402` +#### Removed +- [glycosphingolipid](http://purl.obolibrary.org/obo/CHEBI_24402) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glycosphingolipids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [glycosphingolipid](http://purl.obolibrary.org/obo/CHEBI_24402) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19303901" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycosphingolipid](http://purl.obolibrary.org/obo/CHEBI_24402) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Glycosphingolipid" + +- [glycosphingolipid](http://purl.obolibrary.org/obo/CHEBI_24402) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [glycosphingolipid](http://purl.obolibrary.org/obo/CHEBI_24402) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [glycosphingolipid](http://purl.obolibrary.org/obo/CHEBI_24402) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A glycosphingolipid is a glycolipid that is a carbohydrate-containing derivative of a sphingoid or ceramide. It is understood that the carbohydrate residue is attached by a glycosidic linkage to O-1 of the sphingoid." + +- [glycosphingolipid](http://purl.obolibrary.org/obo/CHEBI_24402) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5498" + +- [glycosphingolipid](http://purl.obolibrary.org/obo/CHEBI_24402) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:26976737" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycosphingolipid](http://purl.obolibrary.org/obo/CHEBI_24402) [label](http://www.w3.org/2000/01/rdf-schema#label) "glycosphingolipid" + +- [glycosphingolipid](http://purl.obolibrary.org/obo/CHEBI_24402) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24402" + +- [glycosphingolipid](http://purl.obolibrary.org/obo/CHEBI_24402) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:27253729" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycosphingolipid](http://purl.obolibrary.org/obo/CHEBI_24402) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:26954668" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycosphingolipid](http://purl.obolibrary.org/obo/CHEBI_24402) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18845618" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycosphingolipid](http://purl.obolibrary.org/obo/CHEBI_24402) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:27325407" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [glycosphingolipid](http://purl.obolibrary.org/obo/CHEBI_24402) SubClassOf [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739) + +- [glycosphingolipid](http://purl.obolibrary.org/obo/CHEBI_24402) SubClassOf [glycolipid](http://purl.obolibrary.org/obo/CHEBI_33563) + + + +### glycosphingolipid binding `http://purl.obolibrary.org/obo/GO_0043208` +#### Removed +- [glycosphingolipid binding](http://purl.obolibrary.org/obo/GO_0043208) SubClassOf [sphingolipid binding](http://purl.obolibrary.org/obo/GO_0046625) + +- [glycosphingolipid binding](http://purl.obolibrary.org/obo/GO_0043208) SubClassOf [glycolipid binding](http://purl.obolibrary.org/obo/GO_0051861) + +#### Added +- [glycosphingolipid binding](http://purl.obolibrary.org/obo/GO_0043208) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### glycosphingolipid biosynthetic process `http://purl.obolibrary.org/obo/GO_0006688` +#### Removed +- [glycosphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006688) SubClassOf [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) + +- [glycosphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006688) SubClassOf [glycolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009247) + +#### Added +- [glycosphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006688) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### glycosphingolipid catabolic process `http://purl.obolibrary.org/obo/GO_0046479` +#### Removed +- [glycosphingolipid catabolic process](http://purl.obolibrary.org/obo/GO_0046479) SubClassOf [sphingolipid catabolic process](http://purl.obolibrary.org/obo/GO_0030149) + +- [glycosphingolipid catabolic process](http://purl.obolibrary.org/obo/GO_0046479) SubClassOf [glycolipid catabolic process](http://purl.obolibrary.org/obo/GO_0019377) + +#### Added +- [glycosphingolipid catabolic process](http://purl.obolibrary.org/obo/GO_0046479) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### glycosphingolipid metabolic process `http://purl.obolibrary.org/obo/GO_0006687` +#### Removed +- [glycosphingolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006687) SubClassOf [glycolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006664) + +- [glycosphingolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006687) SubClassOf [sphingolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006665) + +#### Added +- [glycosphingolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006687) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### gonadotropin-releasing hormone neuron `http://purl.obolibrary.org/obo/CL_0011111` +#### Removed +- [gonadotropin-releasing hormone neuron](http://purl.obolibrary.org/obo/CL_0011111) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Neuroendocrine cells that are born in the nasal placode during embryonic development and migrate through the nose and forebrain to the hypothalamus, where they regulate reproduction." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:NV" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21828096" + +- [gonadotropin-releasing hormone neuron](http://purl.obolibrary.org/obo/CL_0011111) [label](http://www.w3.org/2000/01/rdf-schema#label) "gonadotropin releasing neuron" + +- [gonadotropin-releasing hormone neuron](http://purl.obolibrary.org/obo/CL_0011111) EquivalentTo [neuron](http://purl.obolibrary.org/obo/CL_0000540) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [gonadotropin secretion](http://purl.obolibrary.org/obo/GO_0032274)) + +- [gonadotropin-releasing hormone neuron](http://purl.obolibrary.org/obo/CL_0011111) SubClassOf [capable of](http://purl.obolibrary.org/obo/RO_0002215) some [gonadotropin secretion](http://purl.obolibrary.org/obo/GO_0032274) + +#### Added +- [gonadotropin-releasing hormone neuron](http://purl.obolibrary.org/obo/CL_0011111) [label](http://www.w3.org/2000/01/rdf-schema#label) "gonadotropin-releasing hormone neuron" + +- [gonadotropin-releasing hormone neuron](http://purl.obolibrary.org/obo/CL_0011111) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A neuroendocrine cell that secretes gonadotropin-releasing hormone (GnRH). A GnRH neuron is born in the nasal placode during embryonic development and migrates through the nose and forebrain to the hypothalamus. This cell regulates reproduction by secreting GnRH into the pituitary portal vessels to induce the release of gonadotropins into the general circulation." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:NV" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21828096" + +- [gonadotropin-releasing hormone neuron](http://purl.obolibrary.org/obo/CL_0011111) SubClassOf [capable of regulating](http://purl.obolibrary.org/obo/RO_0002596) some [gonadotropin secretion](http://purl.obolibrary.org/obo/GO_0032274) + + +### gonadtroph `http://purl.obolibrary.org/obo/CL_0000437` +#### Removed +- [gonadtroph](http://purl.obolibrary.org/obo/CL_0000437) SubClassOf [gonadotropin-releasing hormone neuron](http://purl.obolibrary.org/obo/CL_0011111) + + + +### granulocyte `http://purl.obolibrary.org/obo/CL_0000094` +#### Removed +- [granulocyte](http://purl.obolibrary.org/obo/CL_0000094) EquivalentTo [myeloid leukocyte](http://purl.obolibrary.org/obo/CL_0000766) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [secretory granule](http://purl.obolibrary.org/obo/GO_0030141)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [carcinoembryonic antigen-related cell adhesion molecule 8](http://purl.obolibrary.org/obo/PR_000001332)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [urokinase plasminogen activator surface receptor](http://purl.obolibrary.org/obo/PR_000001969)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [blood circulation](http://purl.obolibrary.org/obo/GO_0008015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +- [granulocyte](http://purl.obolibrary.org/obo/CL_0000094) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [granulocyte](http://purl.obolibrary.org/obo/CL_0000094) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [granulocyte](http://purl.obolibrary.org/obo/CL_0000094) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [granulocyte](http://purl.obolibrary.org/obo/CL_0000094) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +#### Added +- [granulocyte](http://purl.obolibrary.org/obo/CL_0000094) EquivalentTo [myeloid leukocyte](http://purl.obolibrary.org/obo/CL_0000766) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [secretory granule](http://purl.obolibrary.org/obo/GO_0030141)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [carcinoembryonic antigen-related cell adhesion molecule 8](http://purl.obolibrary.org/obo/PR_000001332)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [urokinase plasminogen activator surface receptor](http://purl.obolibrary.org/obo/PR_000001969)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [blood circulation](http://purl.obolibrary.org/obo/GO_0008015)) + +- [granulocyte](http://purl.obolibrary.org/obo/CL_0000094) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [granulocyte](http://purl.obolibrary.org/obo/CL_0000094) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [granulocyte](http://purl.obolibrary.org/obo/CL_0000094) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [granulocyte](http://purl.obolibrary.org/obo/CL_0000094) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + + +### granulocyte monocyte progenitor cell `http://purl.obolibrary.org/obo/CL_0000557` +#### Removed +- [granulocyte monocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000557) EquivalentTo [hematopoietic oligopotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002032) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [bone marrow](http://purl.obolibrary.org/obo/UBERON_0002371)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [transcription factor PU.1](http://purl.obolibrary.org/obo/PR_000001944)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [macrophage differentiation](http://purl.obolibrary.org/obo/GO_0030225)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [granulocyte differentiation](http://purl.obolibrary.org/obo/GO_0030851)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [erythroid transcription factor](http://purl.obolibrary.org/obo/PR_000007857)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [endothelial transcription factor GATA-2](http://purl.obolibrary.org/obo/PR_000007858)) + +- [granulocyte monocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000557) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [erythroid transcription factor](http://purl.obolibrary.org/obo/PR_000007857) + +- [granulocyte monocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000557) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [endothelial transcription factor GATA-2](http://purl.obolibrary.org/obo/PR_000007858) + +#### Added +- [granulocyte monocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000557) EquivalentTo [hematopoietic oligopotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002032) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [bone marrow](http://purl.obolibrary.org/obo/UBERON_0002371)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [transcription factor PU.1](http://purl.obolibrary.org/obo/PR_000001944)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [erythroid transcription factor](http://purl.obolibrary.org/obo/PR_000007857)) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [endothelial transcription factor GATA-2](http://purl.obolibrary.org/obo/PR_000007858)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [macrophage differentiation](http://purl.obolibrary.org/obo/GO_0030225)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [granulocyte differentiation](http://purl.obolibrary.org/obo/GO_0030851)) + +- [granulocyte monocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000557) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [erythroid transcription factor](http://purl.obolibrary.org/obo/PR_000007857) + +- [granulocyte monocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000557) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [endothelial transcription factor GATA-2](http://purl.obolibrary.org/obo/PR_000007858) + + +### greenhouse gas `http://purl.obolibrary.org/obo/CHEBI_76413` +#### Removed +- [greenhouse gas](http://purl.obolibrary.org/obo/CHEBI_76413) [label](http://www.w3.org/2000/01/rdf-schema#label) "greenhouse gas" + +- [greenhouse gas](http://purl.obolibrary.org/obo/CHEBI_76413) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [greenhouse gas](http://purl.obolibrary.org/obo/CHEBI_76413) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [greenhouse gas](http://purl.obolibrary.org/obo/CHEBI_76413) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "greenhouse gases" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [greenhouse gas](http://purl.obolibrary.org/obo/CHEBI_76413) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Greenhouse_gas" + +- [greenhouse gas](http://purl.obolibrary.org/obo/CHEBI_76413) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'." + +- [greenhouse gas](http://purl.obolibrary.org/obo/CHEBI_76413) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:76413" + +- Class: [greenhouse gas](http://purl.obolibrary.org/obo/CHEBI_76413) + +- [greenhouse gas](http://purl.obolibrary.org/obo/CHEBI_76413) SubClassOf [chemical role](http://purl.obolibrary.org/obo/CHEBI_51086) + + + +### gross anatomical part `http://purl.obolibrary.org/obo/CARO_0001008` +#### Removed +- [gross anatomical part](http://purl.obolibrary.org/obo/CARO_0001008) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "mah" + +#### Added +- [gross anatomical part](http://purl.obolibrary.org/obo/CARO_0001008) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0001-9114-8737](https://orcid.org/0000-0001-9114-8737) + + +### group `http://purl.obolibrary.org/obo/CHEBI_24433` +#### Removed +- [group](http://purl.obolibrary.org/obo/CHEBI_24433) [label](http://www.w3.org/2000/01/rdf-schema#label) "group" + +- [group](http://purl.obolibrary.org/obo/CHEBI_24433) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [group](http://purl.obolibrary.org/obo/CHEBI_24433) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Rest" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [group](http://purl.obolibrary.org/obo/CHEBI_24433) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Gruppe" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [group](http://purl.obolibrary.org/obo/CHEBI_24433) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "group" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [group](http://purl.obolibrary.org/obo/CHEBI_24433) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "grupo" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [group](http://purl.obolibrary.org/obo/CHEBI_24433) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "grupos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [group](http://purl.obolibrary.org/obo/CHEBI_24433) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "groupe" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [group](http://purl.obolibrary.org/obo/CHEBI_24433) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24433" + +- [group](http://purl.obolibrary.org/obo/CHEBI_24433) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A defined linked collection of atoms or a single atom within a molecular entity." + +- [group](http://purl.obolibrary.org/obo/CHEBI_24433) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [group](http://purl.obolibrary.org/obo/CHEBI_24433) + +- [group](http://purl.obolibrary.org/obo/CHEBI_24433) SubClassOf [chemical entity](http://purl.obolibrary.org/obo/CHEBI_24431) + +- [group](http://purl.obolibrary.org/obo/CHEBI_24433) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [atom](http://purl.obolibrary.org/obo/CHEBI_33250) + + + +### group 2 innate lymphoid cell, mouse `http://purl.obolibrary.org/obo/CL_0002089` +#### Removed +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) EquivalentTo [group 2 innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001069) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [inducible T-cell costimulator](http://purl.obolibrary.org/obo/PR_000001860)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-17 receptor B](http://purl.obolibrary.org/obo/PR_000008982)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-1 receptor-like 1](http://purl.obolibrary.org/obo/PR_000008994)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of type 2 immune response](http://purl.obolibrary.org/obo/GO_0002830)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-13 production](http://purl.obolibrary.org/obo/GO_0032616)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-2](http://purl.obolibrary.org/obo/PR_000001008)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [bone marrow stromal antigen 2](http://purl.obolibrary.org/obo/PR_000001326)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [natural cytotoxicity triggering receptor 1](http://purl.obolibrary.org/obo/PR_000001893)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [sialic acid-binding Ig-like lectin 5](http://purl.obolibrary.org/obo/PR_000001927)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431)) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [natural cytotoxicity triggering receptor 1](http://purl.obolibrary.org/obo/PR_000001893) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [bone marrow stromal antigen 2](http://purl.obolibrary.org/obo/PR_000001326) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-2](http://purl.obolibrary.org/obo/PR_000001008) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [sialic acid-binding Ig-like lectin 5](http://purl.obolibrary.org/obo/PR_000001927) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +#### Added +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) EquivalentTo [group 2 innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001069) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-2](http://purl.obolibrary.org/obo/PR_000001008)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [bone marrow stromal antigen 2](http://purl.obolibrary.org/obo/PR_000001326)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [natural cytotoxicity triggering receptor 1](http://purl.obolibrary.org/obo/PR_000001893)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [sialic acid-binding Ig-like lectin 5](http://purl.obolibrary.org/obo/PR_000001927)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [inducible T-cell costimulator](http://purl.obolibrary.org/obo/PR_000001860)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-17 receptor B](http://purl.obolibrary.org/obo/PR_000008982)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-1 receptor-like 1](http://purl.obolibrary.org/obo/PR_000008994)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of type 2 immune response](http://purl.obolibrary.org/obo/GO_0002830)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-13 production](http://purl.obolibrary.org/obo/GO_0032616)) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [natural cytotoxicity triggering receptor 1](http://purl.obolibrary.org/obo/PR_000001893) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [bone marrow stromal antigen 2](http://purl.obolibrary.org/obo/PR_000001326) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [sialic acid-binding Ig-like lectin 5](http://purl.obolibrary.org/obo/PR_000001927) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-2](http://purl.obolibrary.org/obo/PR_000001008) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431) + +- [group 2 innate lymphoid cell, mouse](http://purl.obolibrary.org/obo/CL_0002089) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + + +### gut absorptive cell `http://purl.obolibrary.org/obo/CL_0000677` +#### Removed +- [gut absorptive cell](http://purl.obolibrary.org/obo/CL_0000677) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### hadron `http://purl.obolibrary.org/obo/CHEBI_36344` +#### Removed +- [hadron](http://purl.obolibrary.org/obo/CHEBI_36344) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hadron](http://purl.obolibrary.org/obo/CHEBI_36344) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hadron](http://purl.obolibrary.org/obo/CHEBI_36344) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hadrons" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hadron](http://purl.obolibrary.org/obo/CHEBI_36344) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Hadron is a subatomic particle which experiences the strong force." + +- [hadron](http://purl.obolibrary.org/obo/CHEBI_36344) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36344" + +- [hadron](http://purl.obolibrary.org/obo/CHEBI_36344) [label](http://www.w3.org/2000/01/rdf-schema#label) "hadron" + +- Class: [hadron](http://purl.obolibrary.org/obo/CHEBI_36344) + +- [hadron](http://purl.obolibrary.org/obo/CHEBI_36344) SubClassOf [composite particle](http://purl.obolibrary.org/obo/CHEBI_36343) + + + +### hair follicle cell `http://purl.obolibrary.org/obo/CL_0002559` +#### Removed +- [hair follicle cell](http://purl.obolibrary.org/obo/CL_0002559) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### has branching part `http://purl.obolibrary.org/obo/RO_0002569` +#### Removed +- [has branching part](http://purl.obolibrary.org/obo/RO_0002569) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has branching part](http://purl.obolibrary.org/obo/RO_0002569) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has dendrite location `http://purl.obolibrary.org/obo/RO_0002360` +#### Removed +- [has dendrite location](http://purl.obolibrary.org/obo/RO_0002360) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has dendrite location](http://purl.obolibrary.org/obo/RO_0002360) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has developmental contribution from `http://purl.obolibrary.org/obo/RO_0002254` +#### Removed +- [has developmental contribution from](http://purl.obolibrary.org/obo/RO_0002254) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has developmental contribution from](http://purl.obolibrary.org/obo/RO_0002254) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has developmental potential involving `http://purl.obolibrary.org/obo/RO_0002384` +#### Removed +- [has developmental potential involving](http://purl.obolibrary.org/obo/RO_0002384) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has developmental potential involving](http://purl.obolibrary.org/obo/RO_0002384) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has end location `http://purl.obolibrary.org/obo/RO_0002232` +#### Removed +- [has end location](http://purl.obolibrary.org/obo/RO_0002232) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has end location](http://purl.obolibrary.org/obo/RO_0002232) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has fasciculating neuron projection `http://purl.obolibrary.org/obo/RO_0002132` +#### Removed +- [has fasciculating neuron projection](http://purl.obolibrary.org/obo/RO_0002132) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland"@en + +#### Added +- [has fasciculating neuron projection](http://purl.obolibrary.org/obo/RO_0002132) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + + +### has input `http://purl.obolibrary.org/obo/RO_0002233` +#### Removed +- [has input](http://purl.obolibrary.org/obo/RO_0002233) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has input](http://purl.obolibrary.org/obo/RO_0002233) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has muscle antagonist `http://purl.obolibrary.org/obo/RO_0002568` +#### Removed +- [has muscle antagonist](http://purl.obolibrary.org/obo/RO_0002568) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has muscle antagonist](http://purl.obolibrary.org/obo/RO_0002568) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has muscle insertion `http://purl.obolibrary.org/obo/RO_0002373` +#### Removed +- [has muscle insertion](http://purl.obolibrary.org/obo/RO_0002373) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has muscle insertion](http://purl.obolibrary.org/obo/RO_0002373) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has muscle origin `http://purl.obolibrary.org/obo/RO_0002372` +#### Removed +- [has muscle origin](http://purl.obolibrary.org/obo/RO_0002372) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has muscle origin](http://purl.obolibrary.org/obo/RO_0002372) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has output `http://purl.obolibrary.org/obo/RO_0002234` +#### Removed +- [has output](http://purl.obolibrary.org/obo/RO_0002234) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has output](http://purl.obolibrary.org/obo/RO_0002234) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has part structure that is capable of `http://purl.obolibrary.org/obo/RO_0002584` +#### Removed +- [has part structure that is capable of](http://purl.obolibrary.org/obo/RO_0002584) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has part structure that is capable of](http://purl.obolibrary.org/obo/RO_0002584) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has part that occurs in `http://purl.obolibrary.org/obo/RO_0002479` +#### Removed +- [has part that occurs in](http://purl.obolibrary.org/obo/RO_0002479) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has part that occurs in](http://purl.obolibrary.org/obo/RO_0002479) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has plasma membrane part `http://purl.obolibrary.org/obo/RO_0002104` +#### Removed +- [has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Lindsay Cowell" + +- [has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Alexander Diehl" + +- [has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall"@en + +#### Added +- [has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0001-9990-8331](https://orcid.org/0000-0001-9990-8331) + +- [has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0003-1617-8244](https://orcid.org/0000-0003-1617-8244) + +- [has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has postsynaptic terminal in `http://purl.obolibrary.org/obo/RO_0002110` +#### Removed +- [has postsynaptic terminal in](http://purl.obolibrary.org/obo/RO_0002110) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall"@en + +- [has postsynaptic terminal in](http://purl.obolibrary.org/obo/RO_0002110) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland"@en + +#### Added +- [has postsynaptic terminal in](http://purl.obolibrary.org/obo/RO_0002110) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + +- [has postsynaptic terminal in](http://purl.obolibrary.org/obo/RO_0002110) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + + +### has potential to develop into `http://purl.obolibrary.org/obo/RO_0002387` +#### Removed +- [has potential to develop into](http://purl.obolibrary.org/obo/RO_0002387) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has potential to develop into](http://purl.obolibrary.org/obo/RO_0002387) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has potential to developmentally contribute to `http://purl.obolibrary.org/obo/RO_0002385` +#### Removed +- [has potential to developmentally contribute to](http://purl.obolibrary.org/obo/RO_0002385) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has potential to developmentally contribute to](http://purl.obolibrary.org/obo/RO_0002385) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has potential to developmentally induce `http://purl.obolibrary.org/obo/RO_0002386` +#### Removed +- [has potential to developmentally induce](http://purl.obolibrary.org/obo/RO_0002386) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has potential to developmentally induce](http://purl.obolibrary.org/obo/RO_0002386) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has potential to directly develop into `http://purl.obolibrary.org/obo/RO_0002388` +#### Removed +- [has potential to directly develop into](http://purl.obolibrary.org/obo/RO_0002388) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has potential to directly develop into](http://purl.obolibrary.org/obo/RO_0002388) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has primary input `http://purl.obolibrary.org/obo/RO_0004009` +#### Removed +- [has primary input](http://purl.obolibrary.org/obo/RO_0004009) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "cjm" + +#### Added +- [has primary input](http://purl.obolibrary.org/obo/RO_0004009) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has primary input or output `http://purl.obolibrary.org/obo/RO_0004007` +#### Removed +- [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "cjm" + +#### Added +- [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has primary output `http://purl.obolibrary.org/obo/RO_0004008` +#### Removed +- [has primary output](http://purl.obolibrary.org/obo/RO_0004008) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "cjm" + +#### Added +- [has primary output](http://purl.obolibrary.org/obo/RO_0004008) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has skeleton `http://purl.obolibrary.org/obo/RO_0002551` +#### Removed +- [has skeleton](http://purl.obolibrary.org/obo/RO_0002551) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has skeleton](http://purl.obolibrary.org/obo/RO_0002551) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has soma location `http://purl.obolibrary.org/obo/RO_0002100` +#### Removed +- [has soma location](http://purl.obolibrary.org/obo/RO_0002100) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland" + +- [has soma location](http://purl.obolibrary.org/obo/RO_0002100) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Relation between a neuron and an anatomical structure that its soma is part of." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBC:DOS" + +#### Added +- [has soma location](http://purl.obolibrary.org/obo/RO_0002100) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + +- [has soma location](http://purl.obolibrary.org/obo/RO_0002100) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Relation between a neuron and an anatomical structure that its soma is part of." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + + +### has start location `http://purl.obolibrary.org/obo/RO_0002231` +#### Removed +- [has start location](http://purl.obolibrary.org/obo/RO_0002231) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has start location](http://purl.obolibrary.org/obo/RO_0002231) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has synaptic terminal in `http://purl.obolibrary.org/obo/RO_0002130` +#### Removed +- [has synaptic terminal in](http://purl.obolibrary.org/obo/RO_0002130) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland"@en + +- [has synaptic terminal in](http://purl.obolibrary.org/obo/RO_0002130) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBC:DOS" + +#### Added +- [has synaptic terminal in](http://purl.obolibrary.org/obo/RO_0002130) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + +- [has synaptic terminal in](http://purl.obolibrary.org/obo/RO_0002130) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + + +### has synaptic terminal of `http://purl.obolibrary.org/obo/RO_0002006` +#### Removed +- [has synaptic terminal of](http://purl.obolibrary.org/obo/RO_0002006) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland" + +#### Added +- [has synaptic terminal of](http://purl.obolibrary.org/obo/RO_0002006) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + + +### has target end location `http://purl.obolibrary.org/obo/RO_0002339` +#### Removed +- [has target end location](http://purl.obolibrary.org/obo/RO_0002339) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has target end location](http://purl.obolibrary.org/obo/RO_0002339) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has target start location `http://purl.obolibrary.org/obo/RO_0002338` +#### Removed +- [has target start location](http://purl.obolibrary.org/obo/RO_0002338) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [has target start location](http://purl.obolibrary.org/obo/RO_0002338) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### has_boundary `http://purl.obolibrary.org/obo/RO_0002002` +#### Removed +- [has_boundary](http://purl.obolibrary.org/obo/RO_0002002) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland" + +#### Added +- [has_boundary](http://purl.obolibrary.org/obo/RO_0002002) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + + +### has_functional_parent `http://purl.obolibrary.org/obo/chebi#has_functional_parent` +#### Removed +- ObjectProperty: [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) + + + +### has_not_completed `http://purl.obolibrary.org/obo/cl#has_not_completed` +#### Removed +- [has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) [label](http://www.w3.org/2000/01/rdf-schema#label) "has_not_completed" + +- ObjectProperty: [has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) + + + +### has_not_completed `http://purl.obolibrary.org/obo/CL_4030044` + +#### Added +- [has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) [label](http://www.w3.org/2000/01/rdf-schema#label) "has_not_completed" + +- ObjectProperty: [has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) + + +### has_parent_hydride `http://purl.obolibrary.org/obo/chebi#has_parent_hydride` +#### Removed +- ObjectProperty: [has_parent_hydride](http://purl.obolibrary.org/obo/chebi#has_parent_hydride) + + + +### helper property (not for use in curation) `http://purl.obolibrary.org/obo/RO_0002464` +#### Removed +- [helper property (not for use in curation)](http://purl.obolibrary.org/obo/RO_0002464) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [helper property (not for use in curation)](http://purl.obolibrary.org/obo/RO_0002464) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### hematopoietic multipotent progenitor cell `http://purl.obolibrary.org/obo/CL_0000837` +#### Removed +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) EquivalentTo [hematopoietic cell](http://purl.obolibrary.org/obo/CL_0000988) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [multipotent](http://purl.obolibrary.org/obo/PATO_0001402)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +#### Added +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) EquivalentTo [hematopoietic cell](http://purl.obolibrary.org/obo/CL_0000988) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [multipotent](http://purl.obolibrary.org/obo/PATO_0001402)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + + +### hematopoietic oligopotent progenitor cell, lineage-negative `http://purl.obolibrary.org/obo/CL_0001060` +#### Removed +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) EquivalentTo [hematopoietic oligopotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002032) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [oligopotent](http://purl.obolibrary.org/obo/PATO_0001401)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +#### Added +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) EquivalentTo [hematopoietic oligopotent progenitor cell](http://purl.obolibrary.org/obo/CL_0002032) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [oligopotent](http://purl.obolibrary.org/obo/PATO_0001401)) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [hematopoietic oligopotent progenitor cell, lineage-negative](http://purl.obolibrary.org/obo/CL_0001060) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + + +### hematopoietic stem cell `http://purl.obolibrary.org/obo/CL_0000037` +#### Removed +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) EquivalentTo [hematopoietic cell](http://purl.obolibrary.org/obo/CL_0000988) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [hematopoietic progenitor cell differentiation](http://purl.obolibrary.org/obo/GO_0002244)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [somatic stem cell division](http://purl.obolibrary.org/obo/GO_0048103)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +#### Added +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) EquivalentTo [hematopoietic cell](http://purl.obolibrary.org/obo/CL_0000988) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [hematopoietic progenitor cell differentiation](http://purl.obolibrary.org/obo/GO_0002244)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [somatic stem cell division](http://purl.obolibrary.org/obo/GO_0048103)) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + + +### heparin binding `http://purl.obolibrary.org/obo/GO_0008201` +#### Removed +- [heparin binding](http://purl.obolibrary.org/obo/GO_0008201) SubClassOf [sulfur compound binding](http://purl.obolibrary.org/obo/GO_1901681) + +- [heparin binding](http://purl.obolibrary.org/obo/GO_0008201) SubClassOf [glycosaminoglycan binding](http://purl.obolibrary.org/obo/GO_0005539) + +#### Added +- [heparin binding](http://purl.obolibrary.org/obo/GO_0008201) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### heparin biosynthetic process `http://purl.obolibrary.org/obo/GO_0030210` +#### Removed +- [heparin biosynthetic process](http://purl.obolibrary.org/obo/GO_0030210) SubClassOf [glycosaminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006024) + +- [heparin biosynthetic process](http://purl.obolibrary.org/obo/GO_0030210) SubClassOf [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) + +#### Added +- [heparin biosynthetic process](http://purl.obolibrary.org/obo/GO_0030210) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### heparin catabolic process `http://purl.obolibrary.org/obo/GO_0030211` +#### Removed +- [heparin catabolic process](http://purl.obolibrary.org/obo/GO_0030211) SubClassOf [glycosaminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006027) + +- [heparin catabolic process](http://purl.obolibrary.org/obo/GO_0030211) SubClassOf [sulfur compound catabolic process](http://purl.obolibrary.org/obo/GO_0044273) + +#### Added +- [heparin catabolic process](http://purl.obolibrary.org/obo/GO_0030211) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### heparin metabolic process `http://purl.obolibrary.org/obo/GO_0030202` +#### Removed +- [heparin metabolic process](http://purl.obolibrary.org/obo/GO_0030202) SubClassOf [mucopolysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903510) + +- [heparin metabolic process](http://purl.obolibrary.org/obo/GO_0030202) SubClassOf [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) + +#### Added +- [heparin metabolic process](http://purl.obolibrary.org/obo/GO_0030202) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### heparins `http://purl.obolibrary.org/obo/CHEBI_24505` +#### Removed +- [heparins](http://purl.obolibrary.org/obo/CHEBI_24505) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [heparins](http://purl.obolibrary.org/obo/CHEBI_24505) [label](http://www.w3.org/2000/01/rdf-schema#label) "heparins" + +- [heparins](http://purl.obolibrary.org/obo/CHEBI_24505) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24505" + +- [heparins](http://purl.obolibrary.org/obo/CHEBI_24505) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [heparins](http://purl.obolibrary.org/obo/CHEBI_24505) SubClassOf [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) + +- [heparins](http://purl.obolibrary.org/obo/CHEBI_24505) SubClassOf [sulfated glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_35722) + + + +### hepatic oval stem cell `http://purl.obolibrary.org/obo/CL_0002196` +#### Removed +- [hepatic oval stem cell](http://purl.obolibrary.org/obo/CL_0002196) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000036" + + + +### hepatic stellate cell `http://purl.obolibrary.org/obo/CL_0000632` + +#### Added +- [hepatic stellate cell](http://purl.obolibrary.org/obo/CL_0000632) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + + +### hepatocyte `http://purl.obolibrary.org/obo/CL_0000182` +#### Removed +- [hepatocyte](http://purl.obolibrary.org/obo/CL_0000182) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### hepatoprotective agent `http://purl.obolibrary.org/obo/CHEBI_62868` +#### Removed +- [hepatoprotective agent](http://purl.obolibrary.org/obo/CHEBI_62868) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hepatoprotective agent](http://purl.obolibrary.org/obo/CHEBI_62868) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:62868" + +- [hepatoprotective agent](http://purl.obolibrary.org/obo/CHEBI_62868) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hepatoprotective agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hepatoprotective agent](http://purl.obolibrary.org/obo/CHEBI_62868) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any compound that is able to prevent damage to the liver." + +- [hepatoprotective agent](http://purl.obolibrary.org/obo/CHEBI_62868) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hepatoprotector" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hepatoprotective agent](http://purl.obolibrary.org/obo/CHEBI_62868) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hepatoprotective agent](http://purl.obolibrary.org/obo/CHEBI_62868) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antihepatotoxic agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hepatoprotective agent](http://purl.obolibrary.org/obo/CHEBI_62868) [label](http://www.w3.org/2000/01/rdf-schema#label) "hepatoprotective agent" + +- Class: [hepatoprotective agent](http://purl.obolibrary.org/obo/CHEBI_62868) + +- [hepatoprotective agent](http://purl.obolibrary.org/obo/CHEBI_62868) SubClassOf [protective agent](http://purl.obolibrary.org/obo/CHEBI_50267) + + + +### heteroarene `http://purl.obolibrary.org/obo/CHEBI_33833` +#### Removed +- [heteroarene](http://purl.obolibrary.org/obo/CHEBI_33833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hetarenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [heteroarene](http://purl.obolibrary.org/obo/CHEBI_33833) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [heteroarene](http://purl.obolibrary.org/obo/CHEBI_33833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hetarenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + +- [heteroarene](http://purl.obolibrary.org/obo/CHEBI_33833) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33833" + +- [heteroarene](http://purl.obolibrary.org/obo/CHEBI_33833) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "heteroarenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [heteroarene](http://purl.obolibrary.org/obo/CHEBI_33833) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [heteroarene](http://purl.obolibrary.org/obo/CHEBI_33833) [label](http://www.w3.org/2000/01/rdf-schema#label) "heteroarene" + +- [heteroarene](http://purl.obolibrary.org/obo/CHEBI_33833) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "heteroarenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [heteroarene](http://purl.obolibrary.org/obo/CHEBI_33833) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [heteroarene](http://purl.obolibrary.org/obo/CHEBI_33833) + +- [heteroarene](http://purl.obolibrary.org/obo/CHEBI_33833) SubClassOf [organic aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33659) + +- [heteroarene](http://purl.obolibrary.org/obo/CHEBI_33833) SubClassOf [organic heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_24532) + + + +### heteroatomic molecular entity `http://purl.obolibrary.org/obo/CHEBI_37577` +#### Removed +- [heteroatomic molecular entity](http://purl.obolibrary.org/obo/CHEBI_37577) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "heteroatomic molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [heteroatomic molecular entity](http://purl.obolibrary.org/obo/CHEBI_37577) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chemical compound" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [heteroatomic molecular entity](http://purl.obolibrary.org/obo/CHEBI_37577) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [heteroatomic molecular entity](http://purl.obolibrary.org/obo/CHEBI_37577) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:37577" + +- [heteroatomic molecular entity](http://purl.obolibrary.org/obo/CHEBI_37577) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "heteroatomic molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [heteroatomic molecular entity](http://purl.obolibrary.org/obo/CHEBI_37577) [label](http://www.w3.org/2000/01/rdf-schema#label) "heteroatomic molecular entity" + +- [heteroatomic molecular entity](http://purl.obolibrary.org/obo/CHEBI_37577) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecular entity consisting of two or more chemical elements." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [heteroatomic molecular entity](http://purl.obolibrary.org/obo/CHEBI_37577) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [heteroatomic molecular entity](http://purl.obolibrary.org/obo/CHEBI_37577) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chemical compound" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [heteroatomic molecular entity](http://purl.obolibrary.org/obo/CHEBI_37577) + +- [heteroatomic molecular entity](http://purl.obolibrary.org/obo/CHEBI_37577) SubClassOf [polyatomic entity](http://purl.obolibrary.org/obo/CHEBI_36357) + + + +### heterobicyclic compound `http://purl.obolibrary.org/obo/CHEBI_33672` +#### Removed +- [heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33672) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "heterobicyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33672) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33672) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33672" + +- [heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33672) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "heterobicyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33672) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33672) [label](http://www.w3.org/2000/01/rdf-schema#label) "heterobicyclic compound" + +- [heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33672) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33672) + +- [heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33672) SubClassOf [heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_5686) + +- [heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33672) SubClassOf [bicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33636) + + + +### heterocyclic compound `http://purl.obolibrary.org/obo/CHEBI_5686` +#### Removed +- [heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_5686) [label](http://www.w3.org/2000/01/rdf-schema#label) "heterocyclic compound" + +- [heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_5686) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "compuestos heterociclicos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_5686) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "heterocyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_5686) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "compuesto heterociclico" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_5686) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "heterocycle" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_5686) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Heterocyclic compound" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_5686) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_5686) SubClassOf [cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33595) + + + +### heterocyst development `http://purl.obolibrary.org/obo/GO_0043158` +#### Removed +- [heterocyst development](http://purl.obolibrary.org/obo/GO_0043158) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "heterocyst biosynthesis" + +- [heterocyst development](http://purl.obolibrary.org/obo/GO_0043158) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "heterocyst cell differentiation" + +- [heterocyst development](http://purl.obolibrary.org/obo/GO_0043158) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The process in which a relatively unspecialized cell acquires specialized features of a heterocyst, a differentiated cell in certain cyanobacteria whose purpose is to fix nitrogen." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [heterocyst development](http://purl.obolibrary.org/obo/GO_0043158) [label](http://www.w3.org/2000/01/rdf-schema#label) "heterocyst differentiation" + +- [heterocyst development](http://purl.obolibrary.org/obo/GO_0043158) EquivalentTo [cell differentiation](http://purl.obolibrary.org/obo/GO_0030154) and ([results in acquisition of features of](http://purl.obolibrary.org/obo/RO_0002315) some [heterocyst](http://purl.obolibrary.org/obo/CL_0000724)) + +- [heterocyst development](http://purl.obolibrary.org/obo/GO_0043158) SubClassOf [results in acquisition of features of](http://purl.obolibrary.org/obo/RO_0002315) some [heterocyst](http://purl.obolibrary.org/obo/CL_0000724) + +- [heterocyst development](http://purl.obolibrary.org/obo/GO_0043158) SubClassOf [cell differentiation](http://purl.obolibrary.org/obo/GO_0030154) + +#### Added +- [heterocyst development](http://purl.obolibrary.org/obo/GO_0043158) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The cellular developmental process by which a cell becomes a heterocyst, a cell that carries out nitrogen fixation. This process involves changes to the cell wall, expression of nitrogenase and other proteins involved in nitrogen fixation, and degradation of photosystem II, which produces oxygen. This process is known to occur in some cyanobacteria." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:35744626" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11121783" + +- [heterocyst development](http://purl.obolibrary.org/obo/GO_0043158) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "heterocyst cell differentiation" + +- [heterocyst development](http://purl.obolibrary.org/obo/GO_0043158) [label](http://www.w3.org/2000/01/rdf-schema#label) "heterocyst development" + +- [heterocyst development](http://purl.obolibrary.org/obo/GO_0043158) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "heterocyst differentiation" + +- [heterocyst development](http://purl.obolibrary.org/obo/GO_0043158) EquivalentTo [cellular developmental process](http://purl.obolibrary.org/obo/GO_0048869) and ([results in developmental progression of](http://purl.obolibrary.org/obo/RO_0002295) some [heterocyst](http://purl.obolibrary.org/obo/CL_0000724)) + +- [heterocyst development](http://purl.obolibrary.org/obo/GO_0043158) SubClassOf [results in developmental progression of](http://purl.obolibrary.org/obo/RO_0002295) some [heterocyst](http://purl.obolibrary.org/obo/CL_0000724) + +- [heterocyst development](http://purl.obolibrary.org/obo/GO_0043158) SubClassOf [cellular developmental process](http://purl.obolibrary.org/obo/GO_0048869) + + +### heterodetic cyclic peptide `http://purl.obolibrary.org/obo/CHEBI_24533` +#### Removed +- [heterodetic cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_24533) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [heterodetic cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_24533) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "heterodetic cyclic peptide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [heterodetic cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_24533) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24533" + +- [heterodetic cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_24533) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "peptide cyclique heterodetique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [heterodetic cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_24533) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "heterodetic cyclic peptides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [heterodetic cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_24533) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond." + +- [heterodetic cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_24533) [label](http://www.w3.org/2000/01/rdf-schema#label) "heterodetic cyclic peptide" + +- [heterodetic cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_24533) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [heterodetic cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_24533) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "peptido ciclico heterodetico" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- Class: [heterodetic cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_24533) + +- [heterodetic cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_24533) SubClassOf [cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_23449) + + + +### heteroorganic entity `http://purl.obolibrary.org/obo/CHEBI_33285` +#### Removed +- [heteroorganic entity](http://purl.obolibrary.org/obo/CHEBI_33285) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "heteroorganic entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [heteroorganic entity](http://purl.obolibrary.org/obo/CHEBI_33285) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organoelement compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [heteroorganic entity](http://purl.obolibrary.org/obo/CHEBI_33285) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [heteroorganic entity](http://purl.obolibrary.org/obo/CHEBI_33285) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33285" + +- [heteroorganic entity](http://purl.obolibrary.org/obo/CHEBI_33285) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "heteroorganic entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [heteroorganic entity](http://purl.obolibrary.org/obo/CHEBI_33285) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organoelement compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [heteroorganic entity](http://purl.obolibrary.org/obo/CHEBI_33285) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [heteroorganic entity](http://purl.obolibrary.org/obo/CHEBI_33285) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [heteroorganic entity](http://purl.obolibrary.org/obo/CHEBI_33285) [label](http://www.w3.org/2000/01/rdf-schema#label) "heteroorganic entity" + +- Class: [heteroorganic entity](http://purl.obolibrary.org/obo/CHEBI_33285) + +- [heteroorganic entity](http://purl.obolibrary.org/obo/CHEBI_33285) SubClassOf [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) + + + +### heteropolycyclic compound `http://purl.obolibrary.org/obo/CHEBI_33671` +#### Removed +- [heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33671) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33671) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33671) [label](http://www.w3.org/2000/01/rdf-schema#label) "heteropolycyclic compound" + +- [heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33671) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polyheterocyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33671) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A polycyclic compound in which at least one of the rings contains at least one non-carbon atom." + +- [heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33671) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33671" + +- [heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33671) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "heteropolycyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- Class: [heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33671) + +- [heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33671) SubClassOf [polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33635) + +- [heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33671) SubClassOf [heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_5686) + + + +### hexose `http://purl.obolibrary.org/obo/CHEBI_18133` +#### Removed +- [hexose](http://purl.obolibrary.org/obo/CHEBI_18133) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hexose](http://purl.obolibrary.org/obo/CHEBI_18133) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24590" + +- [hexose](http://purl.obolibrary.org/obo/CHEBI_18133) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GlyTouCan:G70994MS" + +- [hexose](http://purl.obolibrary.org/obo/CHEBI_18133) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:18133" + +- [hexose](http://purl.obolibrary.org/obo/CHEBI_18133) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GlyGen:G70994MS" + +- [hexose](http://purl.obolibrary.org/obo/CHEBI_18133) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "WURCS=2.0/1,1,0/[axxxxh-1x_1-5_2*NCC/3=O]/1/" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GlyTouCan" + +- [hexose](http://purl.obolibrary.org/obo/CHEBI_18133) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose)." + +- [hexose](http://purl.obolibrary.org/obo/CHEBI_18133) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5709" + +- [hexose](http://purl.obolibrary.org/obo/CHEBI_18133) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hexoses" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hexose](http://purl.obolibrary.org/obo/CHEBI_18133) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00738" + +- [hexose](http://purl.obolibrary.org/obo/CHEBI_18133) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14399" + +- [hexose](http://purl.obolibrary.org/obo/CHEBI_18133) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hexose](http://purl.obolibrary.org/obo/CHEBI_18133) [label](http://www.w3.org/2000/01/rdf-schema#label) "hexose" + +- [hexose](http://purl.obolibrary.org/obo/CHEBI_18133) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Hexose" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [hexose](http://purl.obolibrary.org/obo/CHEBI_18133) SubClassOf [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) + + + +### hexose biosynthetic process `http://purl.obolibrary.org/obo/GO_0019319` +#### Removed +- [hexose biosynthetic process](http://purl.obolibrary.org/obo/GO_0019319) SubClassOf [monosaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0046364) + +#### Added +- [hexose biosynthetic process](http://purl.obolibrary.org/obo/GO_0019319) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### hexose catabolic process `http://purl.obolibrary.org/obo/GO_0019320` +#### Removed +- [hexose catabolic process](http://purl.obolibrary.org/obo/GO_0019320) SubClassOf [monosaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0046365) + +#### Added +- [hexose catabolic process](http://purl.obolibrary.org/obo/GO_0019320) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### hexose metabolic process `http://purl.obolibrary.org/obo/GO_0019318` +#### Removed +- [hexose metabolic process](http://purl.obolibrary.org/obo/GO_0019318) SubClassOf [monosaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005996) + +#### Added +- [hexose metabolic process](http://purl.obolibrary.org/obo/GO_0019318) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### hexose transmembrane transport `http://purl.obolibrary.org/obo/GO_0008645` +#### Removed +- [hexose transmembrane transport](http://purl.obolibrary.org/obo/GO_0008645) SubClassOf [monosaccharide transmembrane transport](http://purl.obolibrary.org/obo/GO_0015749) + +#### Added +- [hexose transmembrane transport](http://purl.obolibrary.org/obo/GO_0008645) SubClassOf [transmembrane transport](http://purl.obolibrary.org/obo/GO_0055085) + + +### hexose transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015149` +#### Removed +- [hexose transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015149) SubClassOf [monosaccharide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015145) + +#### Added +- [hexose transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015149) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + +### hindlimb zeugopod `http://purl.obolibrary.org/obo/UBERON_0003823` +#### Removed +- [hindlimb zeugopod](http://purl.obolibrary.org/obo/UBERON_0003823) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "posterior region of leg" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24984" + +- [hindlimb zeugopod](http://purl.obolibrary.org/obo/UBERON_0003823) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio cruris posterior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24984" + +- [hindlimb zeugopod](http://purl.obolibrary.org/obo/UBERON_0003823) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "posterior leg region" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24984" + +- [hindlimb zeugopod](http://purl.obolibrary.org/obo/UBERON_0003823) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "posterior curral region" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24984" + +- [hindlimb zeugopod](http://purl.obolibrary.org/obo/UBERON_0003823) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sura" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24984" + +- [hindlimb zeugopod](http://purl.obolibrary.org/obo/UBERON_0003823) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "posterior part of leg" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24984" + +- [hindlimb zeugopod](http://purl.obolibrary.org/obo/UBERON_0003823) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "calf" + +- [hindlimb zeugopod](http://purl.obolibrary.org/obo/UBERON_0003823) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sural region" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24984" + +- [hindlimb zeugopod](http://purl.obolibrary.org/obo/UBERON_0003823) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "calf of leg" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24984" + +- [hindlimb zeugopod](http://purl.obolibrary.org/obo/UBERON_0003823) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio surae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24984" + +- [hindlimb zeugopod](http://purl.obolibrary.org/obo/UBERON_0003823) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24984" + + + +### histamine `http://purl.obolibrary.org/obo/CHEBI_18295` +#### Removed +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:1375" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Histamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "111.07965" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "NCCc1c[nH]cn1" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "InChIKey=NTYJJOPFIAHURM-UHFFFAOYSA-N" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [InChIKey](http://purl.obolibrary.org/obo/fbbt#InChIKey) + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14401" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Histamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "2-(1H-imidazol-4-yl)ethanamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C5H9N3" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:HISTAMINE" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:51-45-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "2-(4-Imidazolyl)ethylamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:HSM" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:2012" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:51-45-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:51-45-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:18295" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24596" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NCCc1c[nH]cn1" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [SMILES](http://purl.obolibrary.org/obo/fbbt#SMILES) + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "2-(1H-imidazol-4-yl)ethanamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "1H-Imidazole-4-ethanamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [InChI](http://purl.obolibrary.org/obo/fbbt#InChI) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "NTYJJOPFIAHURM-UHFFFAOYSA-N" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24101735" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "1H-Imidazole-4-ethanamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00001414" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Histamine" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19843401" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "C5H9N3" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [FORMULA](http://purl.obolibrary.org/obo/fbbt#FORMULA) + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16399866" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A member of the class of imidazoles that is 1H-imidazole substituted at position C-4 by a 2-aminoethyl group." + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19547708" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [mass](http://purl.obolibrary.org/obo/chebi/mass) "111.14518" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D08040" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:817" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An aralkylamine that has formula C5H9N3." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [label](http://www.w3.org/2000/01/rdf-schema#label) "histamine" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:2968" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "HISTAMINE" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00388" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:43187" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22770225" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000870" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "HISTAMINE" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:2012" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "2-(4-Imidazolyl)ethylamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- Class: [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) SubClassOf [aralkylamino compound](http://purl.obolibrary.org/obo/CHEBI_64365) + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [neurotransmitter](http://purl.obolibrary.org/obo/CHEBI_25512) + +- [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) SubClassOf [imidazoles](http://purl.obolibrary.org/obo/CHEBI_24780) + + + +### histamine binding `http://purl.obolibrary.org/obo/GO_0051381` +#### Removed +- [histamine binding](http://purl.obolibrary.org/obo/GO_0051381) SubClassOf [cation binding](http://purl.obolibrary.org/obo/GO_0043169) + +#### Added +- [histamine binding](http://purl.obolibrary.org/obo/GO_0051381) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### histamine secretion, neurotransmission `http://purl.obolibrary.org/obo/GO_0061538` + +#### Added +- [histamine secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061538) EquivalentTo [neurotransmitter secretion](http://purl.obolibrary.org/obo/GO_0007269) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_57595](http://purl.obolibrary.org/obo/CHEBI_57595)) + +- [histamine secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061538) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_57595](http://purl.obolibrary.org/obo/CHEBI_57595) + + +### histamine transport `http://purl.obolibrary.org/obo/GO_0051608` +#### Removed +- [histamine transport](http://purl.obolibrary.org/obo/GO_0051608) SubClassOf [nitrogen compound transport](http://purl.obolibrary.org/obo/GO_0071705) + +#### Added +- [histamine transport](http://purl.obolibrary.org/obo/GO_0051608) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### histaminium `http://purl.obolibrary.org/obo/CHEBI_58432` +#### Removed +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "2-(1H-imidazol-4-yl)ethanaminium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "histaminium cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)/p+1" + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "NTYJJOPFIAHURM-UHFFFAOYSA-O" + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "112.08692" + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "histamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) [mass](http://purl.obolibrary.org/obo/chebi/mass) "112.15300" + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:58432" + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An ammonium ion that is the conjugate acid of histamine protonated on the side-chain nitrogen." + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) [label](http://www.w3.org/2000/01/rdf-schema#label) "histaminium" + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+1" + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C5H10N3" + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[NH3+]CCc1c[nH]cn1" + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) SubClassOf [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [histaminium](http://purl.obolibrary.org/obo/CHEBI_58432) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [histamine](http://purl.obolibrary.org/obo/CHEBI_18295) + + + +### homopolysaccharide `http://purl.obolibrary.org/obo/CHEBI_37164` +#### Removed +- [homopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37164) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [homopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37164) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "homopolysaccharides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [homopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37164) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "homopolysaccharide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [homopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37164) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [homopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37164) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:37164" + +- [homopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37164) [label](http://www.w3.org/2000/01/rdf-schema#label) "homopolysaccharide" + +- [homopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37164) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'." + +- [homopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37164) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "homoglycan" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- Class: [homopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37164) + +- [homopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37164) SubClassOf [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) + + + +### hormone `http://purl.obolibrary.org/obo/CHEBI_24621` +#### Removed +- [hormone](http://purl.obolibrary.org/obo/CHEBI_24621) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "endocrine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hormone](http://purl.obolibrary.org/obo/CHEBI_24621) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hormones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hormone](http://purl.obolibrary.org/obo/CHEBI_24621) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hormone](http://purl.obolibrary.org/obo/CHEBI_24621) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hormone](http://purl.obolibrary.org/obo/CHEBI_24621) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds." + +- [hormone](http://purl.obolibrary.org/obo/CHEBI_24621) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24621" + +- [hormone](http://purl.obolibrary.org/obo/CHEBI_24621) [label](http://www.w3.org/2000/01/rdf-schema#label) "hormone" + +- Class: [hormone](http://purl.obolibrary.org/obo/CHEBI_24621) + +- [hormone](http://purl.obolibrary.org/obo/CHEBI_24621) SubClassOf [molecular messenger](http://purl.obolibrary.org/obo/CHEBI_33280) + +- [hormone](http://purl.obolibrary.org/obo/CHEBI_24621) SubClassOf [agonist](http://purl.obolibrary.org/obo/CHEBI_48705) + + + +### hormone agonist `http://purl.obolibrary.org/obo/CHEBI_51060` +#### Removed +- [hormone agonist](http://purl.obolibrary.org/obo/CHEBI_51060) [label](http://www.w3.org/2000/01/rdf-schema#label) "hormone agonist" + +- [hormone agonist](http://purl.obolibrary.org/obo/CHEBI_51060) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A chemical substance which binds to specific hormone receptors activating the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites." + +- [hormone agonist](http://purl.obolibrary.org/obo/CHEBI_51060) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hormone agonist](http://purl.obolibrary.org/obo/CHEBI_51060) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hormone agonist](http://purl.obolibrary.org/obo/CHEBI_51060) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:51060" + +- Class: [hormone agonist](http://purl.obolibrary.org/obo/CHEBI_51060) + +- [hormone agonist](http://purl.obolibrary.org/obo/CHEBI_51060) SubClassOf [agonist](http://purl.obolibrary.org/obo/CHEBI_48705) + +- [hormone agonist](http://purl.obolibrary.org/obo/CHEBI_51060) SubClassOf [hormone receptor modulator](http://purl.obolibrary.org/obo/CHEBI_51061) + + + +### hormone receptor modulator `http://purl.obolibrary.org/obo/CHEBI_51061` +#### Removed +- [hormone receptor modulator](http://purl.obolibrary.org/obo/CHEBI_51061) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites." + +- [hormone receptor modulator](http://purl.obolibrary.org/obo/CHEBI_51061) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:51061" + +- [hormone receptor modulator](http://purl.obolibrary.org/obo/CHEBI_51061) [label](http://www.w3.org/2000/01/rdf-schema#label) "hormone receptor modulator" + +- [hormone receptor modulator](http://purl.obolibrary.org/obo/CHEBI_51061) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hormone receptor modulators" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hormone receptor modulator](http://purl.obolibrary.org/obo/CHEBI_51061) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hormone receptor modulator](http://purl.obolibrary.org/obo/CHEBI_51061) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [hormone receptor modulator](http://purl.obolibrary.org/obo/CHEBI_51061) + +- [hormone receptor modulator](http://purl.obolibrary.org/obo/CHEBI_51061) SubClassOf [receptor modulator](http://purl.obolibrary.org/obo/CHEBI_90710) + + + +### human metabolite `http://purl.obolibrary.org/obo/CHEBI_77746` +#### Removed +- [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) [label](http://www.w3.org/2000/01/rdf-schema#label) "human metabolite" + +- [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:75770" + +- [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens)." + +- [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "H. sapiens metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Homo sapiens metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "H. sapiens metabolite" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:77746" + +- [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Homo sapiens metabolite" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:77123" + +- Class: [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) SubClassOf [mammalian metabolite](http://purl.obolibrary.org/obo/CHEBI_75768) + + + +### human urinary metabolite `http://purl.obolibrary.org/obo/CHEBI_84087` +#### Removed +- [human urinary metabolite](http://purl.obolibrary.org/obo/CHEBI_84087) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [human urinary metabolite](http://purl.obolibrary.org/obo/CHEBI_84087) [label](http://www.w3.org/2000/01/rdf-schema#label) "human urinary metabolite" + +- [human urinary metabolite](http://purl.obolibrary.org/obo/CHEBI_84087) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "human urinary metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [human urinary metabolite](http://purl.obolibrary.org/obo/CHEBI_84087) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [human urinary metabolite](http://purl.obolibrary.org/obo/CHEBI_84087) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any metabolite (endogenous or exogenous) found in human urine samples." + +- [human urinary metabolite](http://purl.obolibrary.org/obo/CHEBI_84087) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:84087" + +- Class: [human urinary metabolite](http://purl.obolibrary.org/obo/CHEBI_84087) + +- [human urinary metabolite](http://purl.obolibrary.org/obo/CHEBI_84087) SubClassOf [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + + + +### human xenobiotic metabolite `http://purl.obolibrary.org/obo/CHEBI_76967` +#### Removed +- [human xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76967) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:76967" + +- [human xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76967) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [human xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76967) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "human xenobiotic metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [human xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76967) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [human xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76967) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any human metabolite produced by metabolism of a xenobiotic compound in humans." + +- [human xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76967) [label](http://www.w3.org/2000/01/rdf-schema#label) "human xenobiotic metabolite" + +- Class: [human xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76967) + +- [human xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76967) SubClassOf [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [human xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76967) SubClassOf [xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76206) + + + +### hyaluronan biosynthetic process `http://purl.obolibrary.org/obo/GO_0030213` +#### Removed +- [hyaluronan biosynthetic process](http://purl.obolibrary.org/obo/GO_0030213) SubClassOf [glycosaminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006024) + +#### Added +- [hyaluronan biosynthetic process](http://purl.obolibrary.org/obo/GO_0030213) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### hyaluronan catabolic process `http://purl.obolibrary.org/obo/GO_0030214` +#### Removed +- [hyaluronan catabolic process](http://purl.obolibrary.org/obo/GO_0030214) SubClassOf [glycosaminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006027) + +#### Added +- [hyaluronan catabolic process](http://purl.obolibrary.org/obo/GO_0030214) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### hyaluronan metabolic process `http://purl.obolibrary.org/obo/GO_0030212` +#### Removed +- [hyaluronan metabolic process](http://purl.obolibrary.org/obo/GO_0030212) SubClassOf [mucopolysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903510) + +#### Added +- [hyaluronan metabolic process](http://purl.obolibrary.org/obo/GO_0030212) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### hyaluronate `http://purl.obolibrary.org/obo/CHEBI_132153` +#### Removed +- [hyaluronate](http://purl.obolibrary.org/obo/CHEBI_132153) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:132153" + +- [hyaluronate](http://purl.obolibrary.org/obo/CHEBI_132153) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hyaluronate polyanion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hyaluronate](http://purl.obolibrary.org/obo/CHEBI_132153) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [hyaluronate](http://purl.obolibrary.org/obo/CHEBI_132153) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A carbohydrate acid derivative anion obtained by deprotonation of the carboxy groups of hyaluronic acid; major species at pH 7.3." + +- [hyaluronate](http://purl.obolibrary.org/obo/CHEBI_132153) [label](http://www.w3.org/2000/01/rdf-schema#label) "hyaluronate" + +- [hyaluronate](http://purl.obolibrary.org/obo/CHEBI_132153) [formula](http://purl.obolibrary.org/obo/chebi/formula) "(C14H20NO11)n.H2O" + +- [hyaluronate](http://purl.obolibrary.org/obo/CHEBI_132153) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hyaluronate](http://purl.obolibrary.org/obo/CHEBI_132153) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hyaluronate](http://purl.obolibrary.org/obo/CHEBI_132153) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hyaluronan" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- Class: [hyaluronate](http://purl.obolibrary.org/obo/CHEBI_132153) + +- [hyaluronate](http://purl.obolibrary.org/obo/CHEBI_132153) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) + +- [hyaluronate](http://purl.obolibrary.org/obo/CHEBI_132153) SubClassOf [polyanionic polymer](http://purl.obolibrary.org/obo/CHEBI_61469) + +- [hyaluronate](http://purl.obolibrary.org/obo/CHEBI_132153) SubClassOf [carbohydrate acid derivative anion](http://purl.obolibrary.org/obo/CHEBI_63551) + + + +### hyaluronic acid `http://purl.obolibrary.org/obo/CHEBI_16336` +#### Removed +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Hyaluronic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acide hyaluronique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [formula](http://purl.obolibrary.org/obo/chebi/formula) "(C14H21NO12)n" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [label](http://www.w3.org/2000/01/rdf-schema#label) "hyaluronic acid" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0010366" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24622" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:9004-61-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:G10505" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hyaluronan" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14412" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D08043" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hyaluronan" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells." + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:9004-61-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5772" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[beta-D-glucopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)]n" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Hyaluronsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:8187837" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18290544" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:16336" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:8538277" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24623" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18056362" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00518" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acido hialuronico" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[beta-N-Acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)]n" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11122186" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [hyaluronate](http://purl.obolibrary.org/obo/CHEBI_132153) + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) SubClassOf [exopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_72813) + +- [hyaluronic acid](http://purl.obolibrary.org/obo/CHEBI_16336) SubClassOf [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) + + + +### hyaluronic acid binding `http://purl.obolibrary.org/obo/GO_0005540` +#### Removed +- [hyaluronic acid binding](http://purl.obolibrary.org/obo/GO_0005540) SubClassOf [glycosaminoglycan binding](http://purl.obolibrary.org/obo/GO_0005539) + +#### Added +- [hyaluronic acid binding](http://purl.obolibrary.org/obo/GO_0005540) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### hydrides `http://purl.obolibrary.org/obo/CHEBI_33692` +#### Removed +- [hydrides](http://purl.obolibrary.org/obo/CHEBI_33692) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydrides" + +- [hydrides](http://purl.obolibrary.org/obo/CHEBI_33692) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33692" + +- [hydrides](http://purl.obolibrary.org/obo/CHEBI_33692) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Hydrides are chemical compounds of hydrogen with other chemical elements." + +- [hydrides](http://purl.obolibrary.org/obo/CHEBI_33692) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hydrides](http://purl.obolibrary.org/obo/CHEBI_33692) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [hydrides](http://purl.obolibrary.org/obo/CHEBI_33692) + +- [hydrides](http://purl.obolibrary.org/obo/CHEBI_33692) SubClassOf [heteroatomic molecular entity](http://purl.obolibrary.org/obo/CHEBI_37577) + +- [hydrides](http://purl.obolibrary.org/obo/CHEBI_33692) SubClassOf [hydrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33608) + + + +### hydridodioxygen(1+) `http://purl.obolibrary.org/obo/CHEBI_29793` +#### Removed +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+1" + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/O2/c1-2/p+1" + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:508" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) [formula](http://purl.obolibrary.org/obo/chebi/formula) "HO2" + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HOO(+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydridodioxygen(1+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "MYMOFIZGZYHOMD-UHFFFAOYSA-O" + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydridodioxygen(1+)" + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "32.99711" + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H][O+]=O" + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dioxidenium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HO2(+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:29793" + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[HO2](+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) [mass](http://purl.obolibrary.org/obo/chebi/mass) "33.00674" + +- Class: [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) SubClassOf [oxygen hydride](http://purl.obolibrary.org/obo/CHEBI_33693) + +- [hydridodioxygen(1+)](http://purl.obolibrary.org/obo/CHEBI_29793) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [dioxygen](http://purl.obolibrary.org/obo/CHEBI_15379) + + + +### hydridonitrate(2-) `http://purl.obolibrary.org/obo/CHEBI_29340` +#### Removed +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NH(2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-2" + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "imide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:29340" + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydridonitrate(2-)" + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A divalent inorganic anion resulting from the removal of two protons from ammonia." + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/HN/h1H/q-2" + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "15.01200" + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydridonitrate(2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "azanediide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) [mass](http://purl.obolibrary.org/obo/chebi/mass) "15.01468" + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "DZQYTNGKSBCIOE-UHFFFAOYSA-N" + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[N--][H]" + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) [formula](http://purl.obolibrary.org/obo/chebi/formula) "HN" + +- Class: [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [azanide](http://purl.obolibrary.org/obo/CHEBI_29337) + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) SubClassOf [divalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79388) + +- [hydridonitrate(2-)](http://purl.obolibrary.org/obo/CHEBI_29340) SubClassOf [nitrogen hydride](http://purl.obolibrary.org/obo/CHEBI_35106) + + + +### hydrocarbon `http://purl.obolibrary.org/obo/CHEBI_24632` +#### Removed +- [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrocarbon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Kohlenwasserstoffe" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Kohlenwasserstoff" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A compound consisting of carbon and hydrogen only." + +- [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hidrocarburos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hidrocarburo" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydrocarbon" + +- [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrocarbons" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrocarbure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24632" + +- Class: [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) + +- [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) SubClassOf [organic fundamental parent](http://purl.obolibrary.org/obo/CHEBI_33245) + + + +### hydrocarbon biosynthetic process `http://purl.obolibrary.org/obo/GO_0120251` +#### Removed +- [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrocarbon formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of a hydrocarbon, a compound consisting of carbon and hydrogen only." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hydrocarbon" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/19842"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydrocarbon biosynthetic process" + +- [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrocarbon anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2020-09-02T20:35:53Z" + +- [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "krc" + +- [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrocarbon synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrocarbon biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0120251" + +- [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) + +- [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632)) + +- [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) SubClassOf [organic substance biosynthetic process](http://purl.obolibrary.org/obo/GO_1901576) + +- [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) + +- [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) SubClassOf [hydrocarbon metabolic process](http://purl.obolibrary.org/obo/GO_0120252) + + + +### hydrocarbon catabolic process `http://purl.obolibrary.org/obo/GO_0120253` +#### Removed +- [hydrocarbon catabolic process](http://purl.obolibrary.org/obo/GO_0120253) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydrocarbon catabolic process" + +- [hydrocarbon catabolic process](http://purl.obolibrary.org/obo/GO_0120253) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2020-09-02T20:58:57Z" + +- [hydrocarbon catabolic process](http://purl.obolibrary.org/obo/GO_0120253) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "krc" + +- [hydrocarbon catabolic process](http://purl.obolibrary.org/obo/GO_0120253) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrocarbon breakdown" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [hydrocarbon catabolic process](http://purl.obolibrary.org/obo/GO_0120253) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrocarbon degradation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [hydrocarbon catabolic process](http://purl.obolibrary.org/obo/GO_0120253) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrocarbon catabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [hydrocarbon catabolic process](http://purl.obolibrary.org/obo/GO_0120253) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of a hydrocarbon, a compound consisting of carbon and hydrogen only." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hydrocarbon" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [hydrocarbon catabolic process](http://purl.obolibrary.org/obo/GO_0120253) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/19842"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [hydrocarbon catabolic process](http://purl.obolibrary.org/obo/GO_0120253) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [hydrocarbon catabolic process](http://purl.obolibrary.org/obo/GO_0120253) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0120253" + +- Class: [hydrocarbon catabolic process](http://purl.obolibrary.org/obo/GO_0120253) + +- [hydrocarbon catabolic process](http://purl.obolibrary.org/obo/GO_0120253) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632)) + +- [hydrocarbon catabolic process](http://purl.obolibrary.org/obo/GO_0120253) SubClassOf [organic substance catabolic process](http://purl.obolibrary.org/obo/GO_1901575) + +- [hydrocarbon catabolic process](http://purl.obolibrary.org/obo/GO_0120253) SubClassOf [hydrocarbon metabolic process](http://purl.obolibrary.org/obo/GO_0120252) + +- [hydrocarbon catabolic process](http://purl.obolibrary.org/obo/GO_0120253) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) + + + +### hydrocarbon metabolic process `http://purl.obolibrary.org/obo/GO_0120252` +#### Removed +- [hydrocarbon metabolic process](http://purl.obolibrary.org/obo/GO_0120252) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hydrocarbon" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [hydrocarbon metabolic process](http://purl.obolibrary.org/obo/GO_0120252) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydrocarbon metabolic process" + +- [hydrocarbon metabolic process](http://purl.obolibrary.org/obo/GO_0120252) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrocarbon metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [hydrocarbon metabolic process](http://purl.obolibrary.org/obo/GO_0120252) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0120252" + +- [hydrocarbon metabolic process](http://purl.obolibrary.org/obo/GO_0120252) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [hydrocarbon metabolic process](http://purl.obolibrary.org/obo/GO_0120252) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/19842"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [hydrocarbon metabolic process](http://purl.obolibrary.org/obo/GO_0120252) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "krc" + +- [hydrocarbon metabolic process](http://purl.obolibrary.org/obo/GO_0120252) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2020-09-02T20:47:28Z" + +- Class: [hydrocarbon metabolic process](http://purl.obolibrary.org/obo/GO_0120252) + +- [hydrocarbon metabolic process](http://purl.obolibrary.org/obo/GO_0120252) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632)) + +- [hydrocarbon metabolic process](http://purl.obolibrary.org/obo/GO_0120252) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) + +- [hydrocarbon metabolic process](http://purl.obolibrary.org/obo/GO_0120252) SubClassOf [organic substance metabolic process](http://purl.obolibrary.org/obo/GO_0071704) + + + +### hydrogen atom `http://purl.obolibrary.org/obo/CHEBI_49637` +#### Removed +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "YZCKVEUIGOORGS-UHFFFAOYSA-N" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [formula](http://purl.obolibrary.org/obo/chebi/formula) "H" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "1.00783" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrogen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hidrogeno" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/H" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrogene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "H" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:49636" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:49637" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H]" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24634" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "1H" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydrogen atom" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WebElements:H" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Wasserstoff" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) [mass](http://purl.obolibrary.org/obo/chebi/mass) "1.00794" + +- Class: [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) SubClassOf [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) SubClassOf [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [macronutrient](http://purl.obolibrary.org/obo/CHEBI_33937) + +- [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) SubClassOf [s-block element atom](http://purl.obolibrary.org/obo/CHEBI_33559) + + + +### hydrogen molecular entity `http://purl.obolibrary.org/obo/CHEBI_33608` +#### Removed +- [hydrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33608) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrogen compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [hydrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33608) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydrogen molecular entity" + +- [hydrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33608) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33608" + +- [hydrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33608) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrogen molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hydrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33608) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrogen compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hydrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33608) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrogen molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [hydrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33608) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hydrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33608) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [hydrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33608) + +- [hydrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33608) SubClassOf [s-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33674) + +- [hydrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33608) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [hydrogen atom](http://purl.obolibrary.org/obo/CHEBI_49637) + + + +### hydrogencarbonate `http://purl.obolibrary.org/obo/CHEBI_17544` +#### Removed +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HCO3(-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogentrioxocarbonate(IV)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydrogencarbonate" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "60.99312" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:29460248" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:29466234" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "BICARBONATE ION" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:BCT" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:71-52-3" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogen(trioxidocarbonate)(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Acid carbonate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:22863" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogencarbonate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:4208463" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[CO2(OH)](-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogencarbonate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HCO3-" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:29150416" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "BVKZGUZCCUSVTD-UHFFFAOYSA-M" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13363" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Hydrogencarbonate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrogen carbonate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Bicarbonate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogentrioxocarbonate(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28732801" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00288" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:40961" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:HCO3" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:17544" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:49249" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17505962" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:3903504" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Bicarbonate" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [mass](http://purl.obolibrary.org/obo/chebi/mass) "61.01684" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5589" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogencarbonate(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "OC([O-])=O" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17215880" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydroxidodioxidocarbonate(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The carbon oxoanion resulting from the removal of a proton from carbonic acid." + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18439416" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000595" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CHO3" + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [carbonic acid](http://purl.obolibrary.org/obo/CHEBI_28976) + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [cofactor](http://purl.obolibrary.org/obo/CHEBI_23357) + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [carbonate](http://purl.obolibrary.org/obo/CHEBI_41609) + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) SubClassOf [carbon oxoanion](http://purl.obolibrary.org/obo/CHEBI_35604) + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [hydrogencarbonate](http://purl.obolibrary.org/obo/CHEBI_17544) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) + + + +### hydrogenphosphate `http://purl.obolibrary.org/obo/CHEBI_43474` +#### Removed +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:1998" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:43470" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A phosphate ion that is the conjugate base of dihydrogenphosphate." + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:PI" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HYDROGENPHOSPHATE ION" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[PO3(OH)](2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:43474" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "95.96234" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-2" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MolBase:1628" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydroxidotrioxidophosphate(2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HPO4(2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrogen phosphate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "NBIIXXVUZAFLBC-UHFFFAOYSA-L" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:29139" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "OP([O-])([O-])=O" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogentetraoxophosphate(2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-2" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[P(OH)O3](2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MolBase" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:PO4" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "INORGANIC PHOSPHATE GROUP" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydrogenphosphate" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogenphosphate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "phosphate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [formula](http://purl.obolibrary.org/obo/chebi/formula) "HO4P" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [mass](http://purl.obolibrary.org/obo/chebi/mass) "95.97930" + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogen(tetraoxidophosphate)(2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogentetraoxophosphate(V)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- Class: [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) SubClassOf [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) SubClassOf [divalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79388) + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [cofactor](http://purl.obolibrary.org/obo/CHEBI_23357) + +- [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) + + + +### hydrogensulfate `http://purl.obolibrary.org/obo/CHEBI_45696` +#### Removed +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:45696" + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogensulfate(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HYDROGEN SULFATE" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydrogensulfate" + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:29199" + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:2121" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-1" + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HSO4(-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogen(tetraoxidosulfate)(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogentetraoxosulfate(VI)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogensulfate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [formula](http://purl.obolibrary.org/obo/chebi/formula) "HO4S" + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:45693" + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H]OS([O-])(=O)=O" + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydroxidotrioxidosulfate(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "96.96010" + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "QAOWNCQODCNURD-UHFFFAOYSA-M" + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogentetraoxosulfate(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[SO3(OH)](-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) [mass](http://purl.obolibrary.org/obo/chebi/mass) "97.07154" + +- Class: [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) SubClassOf [sulfur oxoanion](http://purl.obolibrary.org/obo/CHEBI_33482) + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) + +- [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) + + + +### hydroxide `http://purl.obolibrary.org/obo/CHEBI_16234` +#### Removed +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HYDROXIDE ION" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5594" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/H2O/h1H2/p-1" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:24714" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "OH(-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01328" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:44641" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "XLYOFNOQVPJJNP-UHFFFAOYSA-M" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxidanide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Hydroxide ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydridooxygenate(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydroxide" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13419" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydroxide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:14280-30-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:OH" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:14280-30-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [formula](http://purl.obolibrary.org/obo/chebi/formula) "HO" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:16234" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "OH-" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [mass](http://purl.obolibrary.org/obo/chebi/mass) "17.00734" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "17.00329" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13365" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HO-" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[O-][H]" + +- Class: [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [water](http://purl.obolibrary.org/obo/CHEBI_15377) + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) SubClassOf [oxygen hydride](http://purl.obolibrary.org/obo/CHEBI_33693) + + + +### hydroxides `http://purl.obolibrary.org/obo/CHEBI_24651` +#### Removed +- [hydroxides](http://purl.obolibrary.org/obo/CHEBI_24651) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24651" + +- [hydroxides](http://purl.obolibrary.org/obo/CHEBI_24651) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hydroxides](http://purl.obolibrary.org/obo/CHEBI_24651) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-))." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [hydroxides](http://purl.obolibrary.org/obo/CHEBI_24651) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydroxides" + +- [hydroxides](http://purl.obolibrary.org/obo/CHEBI_24651) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [hydroxides](http://purl.obolibrary.org/obo/CHEBI_24651) + +- [hydroxides](http://purl.obolibrary.org/obo/CHEBI_24651) SubClassOf [heteroatomic molecular entity](http://purl.obolibrary.org/obo/CHEBI_37577) + +- [hydroxides](http://purl.obolibrary.org/obo/CHEBI_24651) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) + +- [hydroxides](http://purl.obolibrary.org/obo/CHEBI_24651) SubClassOf [hydrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33608) + +- [hydroxides](http://purl.obolibrary.org/obo/CHEBI_24651) SubClassOf [oxygen molecular entity](http://purl.obolibrary.org/obo/CHEBI_25806) + + + +### hydroxy group `http://purl.obolibrary.org/obo/CHEBI_43176` +#### Removed +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "-OH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydroxy group" + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydroxy" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [formula](http://purl.obolibrary.org/obo/chebi/formula) "HO" + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydroxyl group" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydroxyl" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:OH" + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydroxy group" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:43171" + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "*O[H]" + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:43176" + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [mass](http://purl.obolibrary.org/obo/chebi/mass) "17.00734" + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "HYDROXY GROUP" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24706" + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "17.00274" + +- Class: [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) + +- [hydroxy group](http://purl.obolibrary.org/obo/CHEBI_43176) SubClassOf [inorganic group](http://purl.obolibrary.org/obo/CHEBI_33246) + + + +### hydroxy steroid `http://purl.obolibrary.org/obo/CHEBI_35350` +#### Removed +- [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydroxy steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C02159" + +- [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5814" + +- [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydroxysteroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24748" + +- [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydroxy steroid" + +- [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35350" + +- [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Hydroxysteroid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- Class: [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) + +- [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) SubClassOf [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) + +- [hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35350) SubClassOf [organic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_33822) + + + +### hydroxy-5beta-cholanic acid `http://purl.obolibrary.org/obo/CHEBI_24663` +#### Removed +- [hydroxy-5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_24663) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24663" + +- [hydroxy-5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_24663) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hydroxy-5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_24663) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any member of the class of 5beta-cholanic acids carrying at least one hydroxy group at unspecified position." + +- [hydroxy-5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_24663) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydroxy-5beta-cholanic acid" + +- [hydroxy-5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_24663) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydroxy-5beta-cholanic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [hydroxy-5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_24663) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [hydroxy-5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_24663) + +- [hydroxy-5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_24663) SubClassOf [5beta-cholanic acids](http://purl.obolibrary.org/obo/CHEBI_36248) + +- [hydroxy-5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_24663) SubClassOf [organic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_33822) + +- [hydroxy-5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_24663) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [5beta-cholanic acid](http://purl.obolibrary.org/obo/CHEBI_36238) + + + +### hydroxyindoles `http://purl.obolibrary.org/obo/CHEBI_84729` +#### Removed +- [hydroxyindoles](http://purl.obolibrary.org/obo/CHEBI_84729) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hydroxyindoles](http://purl.obolibrary.org/obo/CHEBI_84729) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydroxyindoles" + +- [hydroxyindoles](http://purl.obolibrary.org/obo/CHEBI_84729) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:84729" + +- [hydroxyindoles](http://purl.obolibrary.org/obo/CHEBI_84729) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hydroxyindoles](http://purl.obolibrary.org/obo/CHEBI_84729) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any member of the class of indoles carrying at least one hydroxy group." + +- Class: [hydroxyindoles](http://purl.obolibrary.org/obo/CHEBI_84729) + +- [hydroxyindoles](http://purl.obolibrary.org/obo/CHEBI_84729) SubClassOf [organic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_33822) + +- [hydroxyindoles](http://purl.obolibrary.org/obo/CHEBI_84729) SubClassOf [indoles](http://purl.obolibrary.org/obo/CHEBI_24828) + + + +### hydroxylapatite `http://purl.obolibrary.org/obo/CHEBI_52255` +#### Removed +- [hydroxylapatite](http://purl.obolibrary.org/obo/CHEBI_52255) [label](http://www.w3.org/2000/01/rdf-schema#label) "hydroxylapatite" + +- [hydroxylapatite](http://purl.obolibrary.org/obo/CHEBI_52255) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A phosphate mineral with the formula Ca5(PO4)3(OH)." + +- [hydroxylapatite](http://purl.obolibrary.org/obo/CHEBI_52255) [mass](http://purl.obolibrary.org/obo/chebi/mass) "502.312" + +- [hydroxylapatite](http://purl.obolibrary.org/obo/CHEBI_52255) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "501.67595" + +- [hydroxylapatite](http://purl.obolibrary.org/obo/CHEBI_52255) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [hydroxylapatite](http://purl.obolibrary.org/obo/CHEBI_52255) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [hydroxylapatite](http://purl.obolibrary.org/obo/CHEBI_52255) [formula](http://purl.obolibrary.org/obo/chebi/formula) "Ca5HO13P3" + +- [hydroxylapatite](http://purl.obolibrary.org/obo/CHEBI_52255) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:52255" + +- [hydroxylapatite](http://purl.obolibrary.org/obo/CHEBI_52255) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [hydroxylapatite](http://purl.obolibrary.org/obo/CHEBI_52255) SubClassOf [apatite](http://purl.obolibrary.org/obo/CHEBI_52254) + + + +### hypothalamus cell `http://purl.obolibrary.org/obo/CL_2000030` +#### Removed +- [hypothalamus cell](http://purl.obolibrary.org/obo/CL_2000030) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### iliac artery smooth muscle tissue `http://purl.obolibrary.org/obo/UBERON_8480003` +#### Removed +- [iliac artery smooth muscle tissue](http://purl.obolibrary.org/obo/UBERON_8480003) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](http://orcid.org/0000-0002-0819-0473) + +#### Added +- [iliac artery smooth muscle tissue](http://purl.obolibrary.org/obo/UBERON_8480003) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](https://orcid.org/0000-0002-0819-0473) + + +### iliac vein endothelium `http://purl.obolibrary.org/obo/UBERON_8480004` +#### Removed +- [iliac vein endothelium](http://purl.obolibrary.org/obo/UBERON_8480004) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](http://orcid.org/0000-0002-0819-0473) + +#### Added +- [iliac vein endothelium](http://purl.obolibrary.org/obo/UBERON_8480004) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](https://orcid.org/0000-0002-0819-0473) + + +### iliac vein smooth muscle tissue `http://purl.obolibrary.org/obo/UBERON_8480000` +#### Removed +- [iliac vein smooth muscle tissue](http://purl.obolibrary.org/obo/UBERON_8480000) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](http://orcid.org/0000-0002-0819-0473) + +#### Added +- [iliac vein smooth muscle tissue](http://purl.obolibrary.org/obo/UBERON_8480000) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](https://orcid.org/0000-0002-0819-0473) + + +### imidazole-containing compound catabolic process `http://purl.obolibrary.org/obo/GO_0052805` +#### Removed +- [imidazole-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0052805) SubClassOf [heterocycle catabolic process](http://purl.obolibrary.org/obo/GO_0046700) + +- [imidazole-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0052805) SubClassOf [organic cyclic compound catabolic process](http://purl.obolibrary.org/obo/GO_1901361) + +- [imidazole-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0052805) SubClassOf [organonitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_1901565) + +- [imidazole-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0052805) SubClassOf [aromatic compound catabolic process](http://purl.obolibrary.org/obo/GO_0019439) + + + +### imidazoles `http://purl.obolibrary.org/obo/CHEBI_24780` +#### Removed +- [imidazoles](http://purl.obolibrary.org/obo/CHEBI_24780) [label](http://www.w3.org/2000/01/rdf-schema#label) "imidazoles" + +- [imidazoles](http://purl.obolibrary.org/obo/CHEBI_24780) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [imidazoles](http://purl.obolibrary.org/obo/CHEBI_24780) SubClassOf [diazole](http://purl.obolibrary.org/obo/CHEBI_23677) + + + +### immature B cell `http://purl.obolibrary.org/obo/CL_0000816` +#### Removed +- [immature B cell](http://purl.obolibrary.org/obo/CL_0000816) EquivalentTo [B cell, CD19-positive](http://purl.obolibrary.org/obo/CL_0001201) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [isotype switching](http://purl.obolibrary.org/obo/GO_0045190)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) + +- [immature B cell](http://purl.obolibrary.org/obo/CL_0000816) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [isotype switching](http://purl.obolibrary.org/obo/GO_0045190) + +- [immature B cell](http://purl.obolibrary.org/obo/CL_0000816) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738) + +#### Added +- [immature B cell](http://purl.obolibrary.org/obo/CL_0000816) EquivalentTo [B cell, CD19-positive](http://purl.obolibrary.org/obo/CL_0001201) and ([has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [isotype switching](http://purl.obolibrary.org/obo/GO_0045190)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) + +- [immature B cell](http://purl.obolibrary.org/obo/CL_0000816) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738) + +- [immature B cell](http://purl.obolibrary.org/obo/CL_0000816) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [isotype switching](http://purl.obolibrary.org/obo/GO_0045190) + + +### immature CD11c-negative plasmacytoid dendritic cell `http://purl.obolibrary.org/obo/CL_0000994` +#### Removed +- [immature CD11c-negative plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000994) EquivalentTo [CD11c-negative plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000991) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [antigen processing and presentation](http://purl.obolibrary.org/obo/GO_0019882)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [CD86 molecule](http://purl.obolibrary.org/obo/PR_000001412)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD80 molecule](http://purl.obolibrary.org/obo/PR_000001438)) + +- [immature CD11c-negative plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000994) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD80 molecule](http://purl.obolibrary.org/obo/PR_000001438) + +#### Added +- [immature CD11c-negative plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000994) EquivalentTo [CD11c-negative plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000991) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD80 molecule](http://purl.obolibrary.org/obo/PR_000001438)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [antigen processing and presentation](http://purl.obolibrary.org/obo/GO_0019882)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [CD86 molecule](http://purl.obolibrary.org/obo/PR_000001412)) + +- [immature CD11c-negative plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000994) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD80 molecule](http://purl.obolibrary.org/obo/PR_000001438) + + +### immature NK T cell stage I `http://purl.obolibrary.org/obo/CL_0002039` +#### Removed +- [immature NK T cell stage I](http://purl.obolibrary.org/obo/CL_0002039) EquivalentTo [immature NK T cell](http://purl.obolibrary.org/obo/CL_0000914) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) + +- [immature NK T cell stage I](http://purl.obolibrary.org/obo/CL_0002039) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874) + +- [immature NK T cell stage I](http://purl.obolibrary.org/obo/CL_0002039) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307) + +#### Added +- [immature NK T cell stage I](http://purl.obolibrary.org/obo/CL_0002039) EquivalentTo [immature NK T cell](http://purl.obolibrary.org/obo/CL_0000914) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) + +- [immature NK T cell stage I](http://purl.obolibrary.org/obo/CL_0002039) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874) + +- [immature NK T cell stage I](http://purl.obolibrary.org/obo/CL_0002039) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307) + + +### immature NK T cell stage II `http://purl.obolibrary.org/obo/CL_0002040` +#### Removed +- [immature NK T cell stage II](http://purl.obolibrary.org/obo/CL_0002040) EquivalentTo [immature NK T cell](http://purl.obolibrary.org/obo/CL_0000914) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) + +- [immature NK T cell stage II](http://purl.obolibrary.org/obo/CL_0002040) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874) + +- [immature NK T cell stage II](http://purl.obolibrary.org/obo/CL_0002040) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307) + +#### Added +- [immature NK T cell stage II](http://purl.obolibrary.org/obo/CL_0002040) EquivalentTo [immature NK T cell](http://purl.obolibrary.org/obo/CL_0000914) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) + +- [immature NK T cell stage II](http://purl.obolibrary.org/obo/CL_0002040) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307) + +- [immature NK T cell stage II](http://purl.obolibrary.org/obo/CL_0002040) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874) + + +### immature NK T cell stage III `http://purl.obolibrary.org/obo/CL_0002041` +#### Removed +- [immature NK T cell stage III](http://purl.obolibrary.org/obo/CL_0002041) EquivalentTo [immature NK T cell](http://purl.obolibrary.org/obo/CL_0000914) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [integrin alpha-2](http://purl.obolibrary.org/obo/PR_000001008)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) + +- [immature NK T cell stage III](http://purl.obolibrary.org/obo/CL_0002041) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874) + +#### Added +- [immature NK T cell stage III](http://purl.obolibrary.org/obo/CL_0002041) EquivalentTo [immature NK T cell](http://purl.obolibrary.org/obo/CL_0000914) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [integrin alpha-2](http://purl.obolibrary.org/obo/PR_000001008)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) + +- [immature NK T cell stage III](http://purl.obolibrary.org/obo/CL_0002041) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874) + + +### immature NK T cell stage IV `http://purl.obolibrary.org/obo/CL_0002042` +#### Removed +- [immature NK T cell stage IV](http://purl.obolibrary.org/obo/CL_0002042) EquivalentTo [immature NK T cell](http://purl.obolibrary.org/obo/CL_0000914) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [integrin alpha-2](http://purl.obolibrary.org/obo/PR_000001008)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) + +- [immature NK T cell stage IV](http://purl.obolibrary.org/obo/CL_0002042) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874) + +#### Added +- [immature NK T cell stage IV](http://purl.obolibrary.org/obo/CL_0002042) EquivalentTo [immature NK T cell](http://purl.obolibrary.org/obo/CL_0000914) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [integrin alpha-2](http://purl.obolibrary.org/obo/PR_000001008)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) + +- [immature NK T cell stage IV](http://purl.obolibrary.org/obo/CL_0002042) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874) + + +### immature T cell `http://purl.obolibrary.org/obo/CL_0002420` +#### Removed +- [immature T cell](http://purl.obolibrary.org/obo/CL_0002420) EquivalentTo [T cell](http://purl.obolibrary.org/obo/CL_0000084) and ([has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) + +- [immature T cell](http://purl.obolibrary.org/obo/CL_0002420) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058) + +#### Added +- [immature T cell](http://purl.obolibrary.org/obo/CL_0002420) EquivalentTo [T cell](http://purl.obolibrary.org/obo/CL_0000084) and ([has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) + +- [immature T cell](http://purl.obolibrary.org/obo/CL_0002420) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058) + + +### immature alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000790` +#### Removed +- [immature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000790) EquivalentTo [alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000789) and ([has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) + +#### Added +- [immature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000790) EquivalentTo [alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000789) and ([has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) + + +### immature gamma-delta T cell `http://purl.obolibrary.org/obo/CL_0000799` +#### Removed +- [immature gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000799) EquivalentTo [gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000798) and ([has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [gamma-delta T cell differentiation](http://purl.obolibrary.org/obo/GO_0042492)) and ([has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) + +- [immature gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000799) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [gamma-delta T cell differentiation](http://purl.obolibrary.org/obo/GO_0042492) + +#### Added +- [immature gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000799) EquivalentTo [gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000798) and ([has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [gamma-delta T cell differentiation](http://purl.obolibrary.org/obo/GO_0042492)) and ([has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) + +- [immature gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000799) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [gamma-delta T cell differentiation](http://purl.obolibrary.org/obo/GO_0042492) + + +### immature single positive thymocyte `http://purl.obolibrary.org/obo/CL_0000805` +#### Removed +- [immature single positive thymocyte](http://purl.obolibrary.org/obo/CL_0000805) EquivalentTo [thymocyte](http://purl.obolibrary.org/obo/CL_0000893) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [pre-T cell receptor complex](http://purl.obolibrary.org/obo/GO_0043384)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) + +- [immature single positive thymocyte](http://purl.obolibrary.org/obo/CL_0000805) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + +- [immature single positive thymocyte](http://purl.obolibrary.org/obo/CL_0000805) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [immature single positive thymocyte](http://purl.obolibrary.org/obo/CL_0000805) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307) + +#### Added +- [immature single positive thymocyte](http://purl.obolibrary.org/obo/CL_0000805) EquivalentTo [thymocyte](http://purl.obolibrary.org/obo/CL_0000893) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [pre-T cell receptor complex](http://purl.obolibrary.org/obo/GO_0043384)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [T cell receptor co-receptor CD8](http://purl.obolibrary.org/obo/PR_000025402)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) + +- [immature single positive thymocyte](http://purl.obolibrary.org/obo/CL_0000805) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + +- [immature single positive thymocyte](http://purl.obolibrary.org/obo/CL_0000805) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [immature single positive thymocyte](http://purl.obolibrary.org/obo/CL_0000805) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307) + + +### immediate transformation of `http://purl.obolibrary.org/obo/RO_0002495` +#### Removed +- [immediate transformation of](http://purl.obolibrary.org/obo/RO_0002495) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [immediate transformation of](http://purl.obolibrary.org/obo/RO_0002495) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### immediately causally downstream of `http://purl.obolibrary.org/obo/RO_0002405` +#### Removed +- [immediately causally downstream of](http://purl.obolibrary.org/obo/RO_0002405) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [immediately causally downstream of](http://purl.obolibrary.org/obo/RO_0002405) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### immediately causally upstream of `http://purl.obolibrary.org/obo/RO_0002412` +#### Removed +- [immediately causally upstream of](http://purl.obolibrary.org/obo/RO_0002412) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [immediately causally upstream of](http://purl.obolibrary.org/obo/RO_0002412) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### immediately precedes `http://purl.obolibrary.org/obo/RO_0002090` + +#### Added +- [immediately precedes](http://purl.obolibrary.org/obo/RO_0002090) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + + +### immunoglobulin complex, circulating `http://purl.obolibrary.org/obo/GO_0042571` + +#### Added +- [immunoglobulin complex, circulating](http://purl.obolibrary.org/obo/GO_0042571) EquivalentTo [immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0019814) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [secretion by cell](http://purl.obolibrary.org/obo/GO_0032940)) + +- [immunoglobulin complex, circulating](http://purl.obolibrary.org/obo/GO_0042571) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [secretion by cell](http://purl.obolibrary.org/obo/GO_0032940) + + +### immunological adjuvant `http://purl.obolibrary.org/obo/CHEBI_50847` +#### Removed +- [immunological adjuvant](http://purl.obolibrary.org/obo/CHEBI_50847) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Immunologic_adjuvant" + +- [immunological adjuvant](http://purl.obolibrary.org/obo/CHEBI_50847) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [immunological adjuvant](http://purl.obolibrary.org/obo/CHEBI_50847) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50847" + +- [immunological adjuvant](http://purl.obolibrary.org/obo/CHEBI_50847) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Immunostimulant" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [immunological adjuvant](http://purl.obolibrary.org/obo/CHEBI_50847) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Immunoadjuvant" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [immunological adjuvant](http://purl.obolibrary.org/obo/CHEBI_50847) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity." + +- [immunological adjuvant](http://purl.obolibrary.org/obo/CHEBI_50847) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [immunological adjuvant](http://purl.obolibrary.org/obo/CHEBI_50847) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Immunopotentiator" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [immunological adjuvant](http://purl.obolibrary.org/obo/CHEBI_50847) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Immunologic adjuvant" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [immunological adjuvant](http://purl.obolibrary.org/obo/CHEBI_50847) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Immunoactivator" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [immunological adjuvant](http://purl.obolibrary.org/obo/CHEBI_50847) [label](http://www.w3.org/2000/01/rdf-schema#label) "immunological adjuvant" + +- Class: [immunological adjuvant](http://purl.obolibrary.org/obo/CHEBI_50847) + +- [immunological adjuvant](http://purl.obolibrary.org/obo/CHEBI_50847) SubClassOf [immunomodulator](http://purl.obolibrary.org/obo/CHEBI_50846) + +- [immunological adjuvant](http://purl.obolibrary.org/obo/CHEBI_50847) SubClassOf [adjuvant](http://purl.obolibrary.org/obo/CHEBI_60809) + + + +### immunomodulator `http://purl.obolibrary.org/obo/CHEBI_50846` +#### Removed +- [immunomodulator](http://purl.obolibrary.org/obo/CHEBI_50846) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Immunotherapy" + +- [immunomodulator](http://purl.obolibrary.org/obo/CHEBI_50846) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "immunomodulators" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [immunomodulator](http://purl.obolibrary.org/obo/CHEBI_50846) [label](http://www.w3.org/2000/01/rdf-schema#label) "immunomodulator" + +- [immunomodulator](http://purl.obolibrary.org/obo/CHEBI_50846) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [immunomodulator](http://purl.obolibrary.org/obo/CHEBI_50846) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Immunological factor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [immunomodulator](http://purl.obolibrary.org/obo/CHEBI_50846) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Biomodulator" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [immunomodulator](http://purl.obolibrary.org/obo/CHEBI_50846) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Biologically active substance whose activity affects or plays a role in the functioning of the immune system." + +- [immunomodulator](http://purl.obolibrary.org/obo/CHEBI_50846) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Immune factor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [immunomodulator](http://purl.obolibrary.org/obo/CHEBI_50846) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Immunologic factor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [immunomodulator](http://purl.obolibrary.org/obo/CHEBI_50846) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [immunomodulator](http://purl.obolibrary.org/obo/CHEBI_50846) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50846" + +- Class: [immunomodulator](http://purl.obolibrary.org/obo/CHEBI_50846) + +- [immunomodulator](http://purl.obolibrary.org/obo/CHEBI_50846) SubClassOf [drug](http://purl.obolibrary.org/obo/CHEBI_23888) + +- [immunomodulator](http://purl.obolibrary.org/obo/CHEBI_50846) SubClassOf [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) + + + +### in branching relationship with `http://purl.obolibrary.org/obo/RO_0002375` +#### Removed +- [in branching relationship with](http://purl.obolibrary.org/obo/RO_0002375) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [in branching relationship with](http://purl.obolibrary.org/obo/RO_0002375) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### in taxon `http://purl.obolibrary.org/obo/RO_0002162` +#### Removed +- [in taxon](http://purl.obolibrary.org/obo/RO_0002162) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Jennifer Deegan" + +- [in taxon](http://purl.obolibrary.org/obo/RO_0002162) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall"@en + +#### Added +- [in taxon](http://purl.obolibrary.org/obo/RO_0002162) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + +- [in taxon](http://purl.obolibrary.org/obo/RO_0002162) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [X](https://orcid.org/0000-0001-9227-417X) + + +### inchi `http://purl.obolibrary.org/obo/chebi/inchi` +#### Removed +- AnnotationProperty: [inchi](http://purl.obolibrary.org/obo/chebi/inchi) + + + +### inchikey `http://purl.obolibrary.org/obo/chebi/inchikey` +#### Removed +- AnnotationProperty: [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) + + + +### inclusion compound `http://purl.obolibrary.org/obo/CHEBI_39022` +#### Removed +- [inclusion compound](http://purl.obolibrary.org/obo/CHEBI_39022) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "compuesto de inclusion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [inclusion compound](http://purl.obolibrary.org/obo/CHEBI_39022) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [inclusion compound](http://purl.obolibrary.org/obo/CHEBI_39022) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:39022" + +- [inclusion compound](http://purl.obolibrary.org/obo/CHEBI_39022) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inclusion compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inclusion compound](http://purl.obolibrary.org/obo/CHEBI_39022) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "compuestos de inclusion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [inclusion compound](http://purl.obolibrary.org/obo/CHEBI_39022) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inclusion compound" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [inclusion compound](http://purl.obolibrary.org/obo/CHEBI_39022) [label](http://www.w3.org/2000/01/rdf-schema#label) "inclusion compound" + +- [inclusion compound](http://purl.obolibrary.org/obo/CHEBI_39022) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A complex in which one component (the host) forms a cavity or, in the case of a crystal, a crystal lattice containing spaces in the shape of long tunnels or channels in which molecular entities of a second chemical species (the guest) are located. There is no covalent bonding between guest and host, the attraction being generally due to van der Waals forces." + +- [inclusion compound](http://purl.obolibrary.org/obo/CHEBI_39022) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inclusion complex" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [inclusion compound](http://purl.obolibrary.org/obo/CHEBI_39022) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [inclusion compound](http://purl.obolibrary.org/obo/CHEBI_39022) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "compose d'inclusion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- Class: [inclusion compound](http://purl.obolibrary.org/obo/CHEBI_39022) + +- [inclusion compound](http://purl.obolibrary.org/obo/CHEBI_39022) SubClassOf [non-covalently-bound molecular entity](http://purl.obolibrary.org/obo/CHEBI_50967) + + + +### indirectly negatively regulates `http://purl.obolibrary.org/obo/RO_0002409` +#### Removed +- [indirectly negatively regulates](http://purl.obolibrary.org/obo/RO_0002409) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [indirectly negatively regulates](http://purl.obolibrary.org/obo/RO_0002409) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### indirectly positively regulates `http://purl.obolibrary.org/obo/RO_0002407` +#### Removed +- [indirectly positively regulates](http://purl.obolibrary.org/obo/RO_0002407) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [indirectly positively regulates](http://purl.obolibrary.org/obo/RO_0002407) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### indolalkylamine biosynthetic process `http://purl.obolibrary.org/obo/GO_0046219` +#### Removed +- [indolalkylamine biosynthetic process](http://purl.obolibrary.org/obo/GO_0046219) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "indolalkylamine biosynthesis" + +- [indolalkylamine biosynthetic process](http://purl.obolibrary.org/obo/GO_0046219) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:curators" + +- [indolalkylamine biosynthetic process](http://purl.obolibrary.org/obo/GO_0046219) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "indolalkylamine formation" + +- [indolalkylamine biosynthetic process](http://purl.obolibrary.org/obo/GO_0046219) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "indolalkylamine synthesis" + +- [indolalkylamine biosynthetic process](http://purl.obolibrary.org/obo/GO_0046219) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046219" + +- [indolalkylamine biosynthetic process](http://purl.obolibrary.org/obo/GO_0046219) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "indolalkylamine anabolism" + +- [indolalkylamine biosynthetic process](http://purl.obolibrary.org/obo/GO_0046219) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [indolalkylamine biosynthetic process](http://purl.obolibrary.org/obo/GO_0046219) [label](http://www.w3.org/2000/01/rdf-schema#label) "indolalkylamine biosynthetic process" + +- Class: [indolalkylamine biosynthetic process](http://purl.obolibrary.org/obo/GO_0046219) + +- [indolalkylamine biosynthetic process](http://purl.obolibrary.org/obo/GO_0046219) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [aminoalkylindole](http://purl.obolibrary.org/obo/CHEBI_38631)) + +- [indolalkylamine biosynthetic process](http://purl.obolibrary.org/obo/GO_0046219) SubClassOf [biogenic amine biosynthetic process](http://purl.obolibrary.org/obo/GO_0042401) + +- [indolalkylamine biosynthetic process](http://purl.obolibrary.org/obo/GO_0046219) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [aminoalkylindole](http://purl.obolibrary.org/obo/CHEBI_38631) + +- [indolalkylamine biosynthetic process](http://purl.obolibrary.org/obo/GO_0046219) SubClassOf [indole-containing compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0042435) + +- [indolalkylamine biosynthetic process](http://purl.obolibrary.org/obo/GO_0046219) SubClassOf [indolalkylamine metabolic process](http://purl.obolibrary.org/obo/GO_0006586) + + + +### indolalkylamine metabolic process `http://purl.obolibrary.org/obo/GO_0006586` +#### Removed +- [indolalkylamine metabolic process](http://purl.obolibrary.org/obo/GO_0006586) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [indolalkylamine metabolic process](http://purl.obolibrary.org/obo/GO_0006586) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "indolalkylamine metabolism" + +- [indolalkylamine metabolic process](http://purl.obolibrary.org/obo/GO_0006586) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006586" + +- [indolalkylamine metabolic process](http://purl.obolibrary.org/obo/GO_0006586) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "indolamine metabolism" + +- [indolalkylamine metabolic process](http://purl.obolibrary.org/obo/GO_0006586) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "indolamine metabolic process" + +- [indolalkylamine metabolic process](http://purl.obolibrary.org/obo/GO_0006586) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:curators" + +- [indolalkylamine metabolic process](http://purl.obolibrary.org/obo/GO_0006586) [label](http://www.w3.org/2000/01/rdf-schema#label) "indolalkylamine metabolic process" + +- Class: [indolalkylamine metabolic process](http://purl.obolibrary.org/obo/GO_0006586) + +- [indolalkylamine metabolic process](http://purl.obolibrary.org/obo/GO_0006586) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [aminoalkylindole](http://purl.obolibrary.org/obo/CHEBI_38631)) + +- [indolalkylamine metabolic process](http://purl.obolibrary.org/obo/GO_0006586) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [aminoalkylindole](http://purl.obolibrary.org/obo/CHEBI_38631) + +- [indolalkylamine metabolic process](http://purl.obolibrary.org/obo/GO_0006586) SubClassOf [biogenic amine metabolic process](http://purl.obolibrary.org/obo/GO_0006576) + +- [indolalkylamine metabolic process](http://purl.obolibrary.org/obo/GO_0006586) SubClassOf [indole-containing compound metabolic process](http://purl.obolibrary.org/obo/GO_0042430) + + + +### indole alkaloid `http://purl.obolibrary.org/obo/CHEBI_38958` +#### Removed +- [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24795" + +- [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5901" + +- [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C06073" + +- [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Indole_alkaloid" + +- [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Indole alkaloid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An alkaloid containing an indole skeleton." + +- [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:38958" + +- [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "indole alkaloids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958) [label](http://www.w3.org/2000/01/rdf-schema#label) "indole alkaloid" + +- Class: [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958) + +- [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [indole skeleton](http://purl.obolibrary.org/obo/CHEBI_73398) + +- [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958) SubClassOf [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) + + + +### indole alkaloid biosynthetic process `http://purl.obolibrary.org/obo/GO_0035835` +#### Removed +- [indole alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0035835) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [indole alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0035835) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0035835" + +- [indole alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0035835) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "indole alkaloid biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:bf" + +- [indole alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0035835) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "indole alkaloid formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:bf" + +- [indole alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0035835) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "indole alkaloid anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:bf" + +- [indole alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0035835) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "bf" + +- [indole alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0035835) [label](http://www.w3.org/2000/01/rdf-schema#label) "indole alkaloid biosynthetic process" + +- [indole alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0035835) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-05-04T03:18:31Z" + +- [indole alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0035835) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:yaf" + +- [indole alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0035835) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "indole alkaloid synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:bf" + +- Class: [indole alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0035835) + +- [indole alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0035835) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958)) + +- [indole alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0035835) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958) + +- [indole alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0035835) SubClassOf [alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009821) + +- [indole alkaloid biosynthetic process](http://purl.obolibrary.org/obo/GO_0035835) SubClassOf [indole alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0035834) + + + +### indole alkaloid metabolic process `http://purl.obolibrary.org/obo/GO_0035834` +#### Removed +- [indole alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0035834) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "indole alkaloid metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:bf" + +- [indole alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0035834) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-05-04T03:17:44Z" + +- [indole alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0035834) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0035834" + +- [indole alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0035834) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:yaf" + +- [indole alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0035834) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "bf" + +- [indole alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0035834) [label](http://www.w3.org/2000/01/rdf-schema#label) "indole alkaloid metabolic process" + +- [indole alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0035834) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [indole alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0035834) + +- [indole alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0035834) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958)) + +- [indole alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0035834) SubClassOf [alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0009820) + +- [indole alkaloid metabolic process](http://purl.obolibrary.org/obo/GO_0035834) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958) + + + +### indole skeleton `http://purl.obolibrary.org/obo/CHEBI_73398` +#### Removed +- [indole skeleton](http://purl.obolibrary.org/obo/CHEBI_73398) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "110.00307" + +- [indole skeleton](http://purl.obolibrary.org/obo/CHEBI_73398) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [indole skeleton](http://purl.obolibrary.org/obo/CHEBI_73398) [mass](http://purl.obolibrary.org/obo/chebi/mass) "110.09230" + +- [indole skeleton](http://purl.obolibrary.org/obo/CHEBI_73398) [label](http://www.w3.org/2000/01/rdf-schema#label) "indole skeleton" + +- [indole skeleton](http://purl.obolibrary.org/obo/CHEBI_73398) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:73398" + +- [indole skeleton](http://purl.obolibrary.org/obo/CHEBI_73398) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C1(=C(C(=C2C(=C1*)N(C(=C2*)*)*)*)*)*" + +- [indole skeleton](http://purl.obolibrary.org/obo/CHEBI_73398) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [indole skeleton](http://purl.obolibrary.org/obo/CHEBI_73398) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [indole skeleton](http://purl.obolibrary.org/obo/CHEBI_73398) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring." + +- [indole skeleton](http://purl.obolibrary.org/obo/CHEBI_73398) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C8N" + +- Class: [indole skeleton](http://purl.obolibrary.org/obo/CHEBI_73398) + +- [indole skeleton](http://purl.obolibrary.org/obo/CHEBI_73398) SubClassOf [organic heterobicyclic ring](http://purl.obolibrary.org/obo/CHEBI_73541) + + + +### indole-containing compound catabolic process `http://purl.obolibrary.org/obo/GO_0042436` +#### Removed +- [indole-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0042436) SubClassOf [organonitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_1901565) + +- [indole-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0042436) SubClassOf [aromatic compound catabolic process](http://purl.obolibrary.org/obo/GO_0019439) + +- [indole-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0042436) SubClassOf [organic cyclic compound catabolic process](http://purl.obolibrary.org/obo/GO_1901361) + +- [indole-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0042436) SubClassOf [heterocycle catabolic process](http://purl.obolibrary.org/obo/GO_0046700) + + + +### indoles `http://purl.obolibrary.org/obo/CHEBI_24828` +#### Removed +- [indoles](http://purl.obolibrary.org/obo/CHEBI_24828) [label](http://www.w3.org/2000/01/rdf-schema#label) "indoles" + +- [indoles](http://purl.obolibrary.org/obo/CHEBI_24828) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [indoles](http://purl.obolibrary.org/obo/CHEBI_24828) SubClassOf [benzopyrrole](http://purl.obolibrary.org/obo/CHEBI_22728) + + + +### inflammatory cell `http://purl.obolibrary.org/obo/CL_0009002` +#### Removed +- [inflammatory cell](http://purl.obolibrary.org/obo/CL_0009002) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### information biomacromolecule `http://purl.obolibrary.org/obo/CHEBI_33695` +#### Removed +- [information biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33695) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [information biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33695) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [information biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33695) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "information biomacromolecules" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [information biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33695) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "genetically encoded biopolymers" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [information biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33695) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "information macromolecules" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [information biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33695) [label](http://www.w3.org/2000/01/rdf-schema#label) "information biomacromolecule" + +- [information biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33695) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "information biopolymers" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [information biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33695) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33695" + +- [information biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33695) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "genetically encoded biomacromolecules" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [information biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33695) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "information macromolecule" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [information biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33695) + +- [information biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33695) SubClassOf [biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33694) + + + +### inhibitor `http://purl.obolibrary.org/obo/CHEBI_35222` +#### Removed +- [inhibitor](http://purl.obolibrary.org/obo/CHEBI_35222) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35222" + +- [inhibitor](http://purl.obolibrary.org/obo/CHEBI_35222) [label](http://www.w3.org/2000/01/rdf-schema#label) "inhibitor" + +- [inhibitor](http://purl.obolibrary.org/obo/CHEBI_35222) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibitor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [inhibitor](http://purl.obolibrary.org/obo/CHEBI_35222) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [inhibitor](http://purl.obolibrary.org/obo/CHEBI_35222) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inhibiteur" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inhibitor](http://purl.obolibrary.org/obo/CHEBI_35222) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inhibitors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inhibitor](http://purl.obolibrary.org/obo/CHEBI_35222) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [inhibitor](http://purl.obolibrary.org/obo/CHEBI_35222) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inhibidor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inhibitor](http://purl.obolibrary.org/obo/CHEBI_35222) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A substance that diminishes the rate of a chemical reaction." + +- Class: [inhibitor](http://purl.obolibrary.org/obo/CHEBI_35222) + +- [inhibitor](http://purl.obolibrary.org/obo/CHEBI_35222) SubClassOf [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) + + + +### innate lymphoid cell `http://purl.obolibrary.org/obo/CL_0001065` +#### Removed +- [innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001065) EquivalentTo [lymphocyte](http://purl.obolibrary.org/obo/CL_0000542) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [cytokine production](http://purl.obolibrary.org/obo/GO_0001816)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [innate immune response](http://purl.obolibrary.org/obo/GO_0045087)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) + +- [innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001065) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001065) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +#### Added +- [innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001065) EquivalentTo [lymphocyte](http://purl.obolibrary.org/obo/CL_0000542) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [cytokine production](http://purl.obolibrary.org/obo/GO_0001816)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [innate immune response](http://purl.obolibrary.org/obo/GO_0045087)) + +- [innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001065) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001065) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + + +### inner cell mass cell `http://purl.obolibrary.org/obo/CL_2000020` +#### Removed +- [inner cell mass cell](http://purl.obolibrary.org/obo/CL_2000020) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### inner chondrogenic layer of perichondrium `http://purl.obolibrary.org/obo/UBERON_0008304` + +#### Added +- [inner chondrogenic layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008304) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [inner chondrogenic layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008304) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:The_Free_Encyclopedia" + +- [inner chondrogenic layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008304) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The perichondrium consists of two separate layers: an outer fibrous layer and inner chondrogenic layer. The chondrogenic layer remains undifferentiated and can form chondroblasts or chondrocytes." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:The_Free_Encyclopedia" + +- [inner chondrogenic layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008304) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0005090" + +- [inner chondrogenic layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008304) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0008304" + +- [inner chondrogenic layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008304) [label](http://www.w3.org/2000/01/rdf-schema#label) "inner chondrogenic layer of perichondrium" + +- Class: [inner chondrogenic layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008304) + +- [inner chondrogenic layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008304) SubClassOf [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Vertebrata ](http://purl.obolibrary.org/obo/NCBITaxon_7742) + +- [inner chondrogenic layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008304) SubClassOf [connective tissue](http://purl.obolibrary.org/obo/UBERON_0002384) + +- [inner chondrogenic layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008304) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) + - [source](http://www.geneontology.org/formats/oboInOwl#source) "BTO" + + +### innervated_by `http://purl.obolibrary.org/obo/RO_0002005` +#### Removed +- [innervated_by](http://purl.obolibrary.org/obo/RO_0002005) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland" + +#### Added +- [innervated_by](http://purl.obolibrary.org/obo/RO_0002005) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + + +### innervates `http://purl.obolibrary.org/obo/RO_0002134` +#### Removed +- [innervates](http://purl.obolibrary.org/obo/RO_0002134) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBC:DOS" + +- [innervates](http://purl.obolibrary.org/obo/RO_0002134) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland"@en + +#### Added +- [innervates](http://purl.obolibrary.org/obo/RO_0002134) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + +- [innervates](http://purl.obolibrary.org/obo/RO_0002134) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + + +### inorganic acid `http://purl.obolibrary.org/obo/CHEBI_138103` +#### Removed +- [inorganic acid](http://purl.obolibrary.org/obo/CHEBI_138103) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [inorganic acid](http://purl.obolibrary.org/obo/CHEBI_138103) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mineral acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic acid](http://purl.obolibrary.org/obo/CHEBI_138103) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mineral_acid" + +- [inorganic acid](http://purl.obolibrary.org/obo/CHEBI_138103) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [inorganic acid](http://purl.obolibrary.org/obo/CHEBI_138103) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:138103" + +- [inorganic acid](http://purl.obolibrary.org/obo/CHEBI_138103) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inorganic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic acid](http://purl.obolibrary.org/obo/CHEBI_138103) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mineral acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic acid](http://purl.obolibrary.org/obo/CHEBI_138103) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water." + +- [inorganic acid](http://purl.obolibrary.org/obo/CHEBI_138103) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic acid" + +- Class: [inorganic acid](http://purl.obolibrary.org/obo/CHEBI_138103) + +- [inorganic acid](http://purl.obolibrary.org/obo/CHEBI_138103) SubClassOf [Bronsted acid](http://purl.obolibrary.org/obo/CHEBI_39141) + + + +### inorganic anion `http://purl.obolibrary.org/obo/CHEBI_24834` +#### Removed +- [inorganic anion](http://purl.obolibrary.org/obo/CHEBI_24834) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [inorganic anion](http://purl.obolibrary.org/obo/CHEBI_24834) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24834" + +- [inorganic anion](http://purl.obolibrary.org/obo/CHEBI_24834) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [inorganic anion](http://purl.obolibrary.org/obo/CHEBI_24834) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inorganic anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic anion](http://purl.obolibrary.org/obo/CHEBI_24834) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic anion" + +- Class: [inorganic anion](http://purl.obolibrary.org/obo/CHEBI_24834) + +- [inorganic anion](http://purl.obolibrary.org/obo/CHEBI_24834) SubClassOf [inorganic ion](http://purl.obolibrary.org/obo/CHEBI_36914) + +- [inorganic anion](http://purl.obolibrary.org/obo/CHEBI_24834) SubClassOf [anion](http://purl.obolibrary.org/obo/CHEBI_22563) + + + +### inorganic anion transmembrane transport `http://purl.obolibrary.org/obo/GO_0098661` +#### Removed +- [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "transmembrane inorganic anion transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The process in which an inorganic anion is transported across a membrane." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Note that this term is not intended for use in annotating lateral movement within membranes." + +- [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inorganic anion membrane transport" + +- [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0098661" + +- [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic anion transmembrane transport" + +- Class: [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661) + +- [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([results in transport across](http://purl.obolibrary.org/obo/RO_0002342) some [membrane](http://purl.obolibrary.org/obo/GO_0016020)) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [inorganic anion](http://purl.obolibrary.org/obo/CHEBI_24834)) + +- [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661) SubClassOf [inorganic ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098660) + +- [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661) SubClassOf [inorganic anion transport](http://purl.obolibrary.org/obo/GO_0015698) + + + +### inorganic anion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015103` +#### Removed +- [inorganic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015103) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015103" + +- [inorganic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015103) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [inorganic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015103) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [inorganic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015103) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic anion transmembrane transporter activity" + +- Class: [inorganic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015103) + +- [inorganic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015103) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [inorganic anion](http://purl.obolibrary.org/obo/CHEBI_24834)) + +- [inorganic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015103) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [inorganic anion](http://purl.obolibrary.org/obo/CHEBI_24834) + +- [inorganic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015103) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [inorganic anion transport](http://purl.obolibrary.org/obo/GO_0015698) + +- [inorganic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015103) SubClassOf [inorganic molecular entity transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015318) + + + +### inorganic anion transport `http://purl.obolibrary.org/obo/GO_0015698` +#### Removed +- [inorganic anion transport](http://purl.obolibrary.org/obo/GO_0015698) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015698" + +- [inorganic anion transport](http://purl.obolibrary.org/obo/GO_0015698) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [inorganic anion transport](http://purl.obolibrary.org/obo/GO_0015698) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic anion transport" + +- [inorganic anion transport](http://purl.obolibrary.org/obo/GO_0015698) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- Class: [inorganic anion transport](http://purl.obolibrary.org/obo/GO_0015698) + +- [inorganic anion transport](http://purl.obolibrary.org/obo/GO_0015698) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [inorganic anion](http://purl.obolibrary.org/obo/CHEBI_24834)) + +- [inorganic anion transport](http://purl.obolibrary.org/obo/GO_0015698) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [inorganic anion](http://purl.obolibrary.org/obo/CHEBI_24834) + +- [inorganic anion transport](http://purl.obolibrary.org/obo/GO_0015698) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + + +### inorganic cation `http://purl.obolibrary.org/obo/CHEBI_36915` +#### Removed +- [inorganic cation](http://purl.obolibrary.org/obo/CHEBI_36915) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inorganic cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic cation](http://purl.obolibrary.org/obo/CHEBI_36915) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36915" + +- [inorganic cation](http://purl.obolibrary.org/obo/CHEBI_36915) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [inorganic cation](http://purl.obolibrary.org/obo/CHEBI_36915) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [inorganic cation](http://purl.obolibrary.org/obo/CHEBI_36915) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic cation" + +- Class: [inorganic cation](http://purl.obolibrary.org/obo/CHEBI_36915) + +- [inorganic cation](http://purl.obolibrary.org/obo/CHEBI_36915) SubClassOf [inorganic ion](http://purl.obolibrary.org/obo/CHEBI_36914) + +- [inorganic cation](http://purl.obolibrary.org/obo/CHEBI_36915) SubClassOf [cation](http://purl.obolibrary.org/obo/CHEBI_36916) + + + +### inorganic cation transmembrane transport `http://purl.obolibrary.org/obo/GO_0098662` +#### Removed +- [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "monovalent inorganic cation transport" + +- [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic cation transmembrane transport" + +- [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0015672" + +- [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "divalent inorganic cation transport" + +- [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Note that this term is not intended for use in annotating lateral movement within membranes." + +- [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0072511" + +- [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "transmembrane inorganic cation transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0098662" + +- [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inorganic cation membrane transport" + +- [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- Class: [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) + +- [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([results in transport across](http://purl.obolibrary.org/obo/RO_0002342) some [membrane](http://purl.obolibrary.org/obo/GO_0016020)) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [inorganic cation](http://purl.obolibrary.org/obo/CHEBI_36915)) + +- [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [inorganic cation](http://purl.obolibrary.org/obo/CHEBI_36915) + +- [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) SubClassOf [inorganic ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098660) + + + +### inorganic cation transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0022890` +#### Removed +- [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "monovalent inorganic cation transmembrane transporter activity" + +- [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "di-, tri-valent inorganic cation transmembrane transporter activity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0015077" + +- [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0072509" + +- [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "divalent inorganic cation transmembrane transporter activity" + +- [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0015082" + +- [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0815340729" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_transport" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0022890" + +- [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "trivalent inorganic cation transmembrane transporter activity" + +- [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic cation transmembrane transporter activity" + +- [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0072510" + +- Class: [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) + +- [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [inorganic cation](http://purl.obolibrary.org/obo/CHEBI_36915)) + +- [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [inorganic cation](http://purl.obolibrary.org/obo/CHEBI_36915) + +- [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) SubClassOf [inorganic molecular entity transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015318) + + + +### inorganic group `http://purl.obolibrary.org/obo/CHEBI_33246` +#### Removed +- [inorganic group](http://purl.obolibrary.org/obo/CHEBI_33246) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33246" + +- [inorganic group](http://purl.obolibrary.org/obo/CHEBI_33246) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inorganic groups" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic group](http://purl.obolibrary.org/obo/CHEBI_33246) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any substituent group which does not contain carbon." + +- [inorganic group](http://purl.obolibrary.org/obo/CHEBI_33246) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [inorganic group](http://purl.obolibrary.org/obo/CHEBI_33246) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic group" + +- [inorganic group](http://purl.obolibrary.org/obo/CHEBI_33246) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [inorganic group](http://purl.obolibrary.org/obo/CHEBI_33246) + +- [inorganic group](http://purl.obolibrary.org/obo/CHEBI_33246) SubClassOf [group](http://purl.obolibrary.org/obo/CHEBI_24433) + + + +### inorganic hydride `http://purl.obolibrary.org/obo/CHEBI_33242` +#### Removed +- [inorganic hydride](http://purl.obolibrary.org/obo/CHEBI_33242) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33242" + +- [inorganic hydride](http://purl.obolibrary.org/obo/CHEBI_33242) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [inorganic hydride](http://purl.obolibrary.org/obo/CHEBI_33242) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [inorganic hydride](http://purl.obolibrary.org/obo/CHEBI_33242) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic hydride" + +- [inorganic hydride](http://purl.obolibrary.org/obo/CHEBI_33242) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inorganic hydrides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [inorganic hydride](http://purl.obolibrary.org/obo/CHEBI_33242) + +- [inorganic hydride](http://purl.obolibrary.org/obo/CHEBI_33242) SubClassOf [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) + +- [inorganic hydride](http://purl.obolibrary.org/obo/CHEBI_33242) SubClassOf [hydrides](http://purl.obolibrary.org/obo/CHEBI_33692) + + + +### inorganic hydroxy compound `http://purl.obolibrary.org/obo/CHEBI_52625` +#### Removed +- [inorganic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_52625) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic hydroxy compound" + +- [inorganic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_52625) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [inorganic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_52625) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [inorganic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_52625) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inorganic hydroxides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_52625) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:52625" + +- Class: [inorganic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_52625) + +- [inorganic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_52625) SubClassOf [hydroxides](http://purl.obolibrary.org/obo/CHEBI_24651) + +- [inorganic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_52625) SubClassOf [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) + + + +### inorganic ion `http://purl.obolibrary.org/obo/CHEBI_36914` +#### Removed +- [inorganic ion](http://purl.obolibrary.org/obo/CHEBI_36914) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inorganic ions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic ion](http://purl.obolibrary.org/obo/CHEBI_36914) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [inorganic ion](http://purl.obolibrary.org/obo/CHEBI_36914) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic ion" + +- [inorganic ion](http://purl.obolibrary.org/obo/CHEBI_36914) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36914" + +- [inorganic ion](http://purl.obolibrary.org/obo/CHEBI_36914) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [inorganic ion](http://purl.obolibrary.org/obo/CHEBI_36914) + +- [inorganic ion](http://purl.obolibrary.org/obo/CHEBI_36914) SubClassOf [ion](http://purl.obolibrary.org/obo/CHEBI_24870) + +- [inorganic ion](http://purl.obolibrary.org/obo/CHEBI_36914) SubClassOf [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) + + + +### inorganic ion homeostasis `http://purl.obolibrary.org/obo/GO_0098771` +#### Removed +- [inorganic ion homeostasis](http://purl.obolibrary.org/obo/GO_0098771) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [inorganic ion homeostasis](http://purl.obolibrary.org/obo/GO_0098771) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic ion homeostasis" + +- [inorganic ion homeostasis](http://purl.obolibrary.org/obo/GO_0098771) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dos" + +- [inorganic ion homeostasis](http://purl.obolibrary.org/obo/GO_0098771) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0098771" + +- [inorganic ion homeostasis](http://purl.obolibrary.org/obo/GO_0098771) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24455"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- Class: [inorganic ion homeostasis](http://purl.obolibrary.org/obo/GO_0098771) + +- [inorganic ion homeostasis](http://purl.obolibrary.org/obo/GO_0098771) EquivalentTo [homeostatic process](http://purl.obolibrary.org/obo/GO_0042592) and ([regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [inorganic ion](http://purl.obolibrary.org/obo/CHEBI_36914)) + +- [inorganic ion homeostasis](http://purl.obolibrary.org/obo/GO_0098771) SubClassOf [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [inorganic ion](http://purl.obolibrary.org/obo/CHEBI_36914) + +- [inorganic ion homeostasis](http://purl.obolibrary.org/obo/GO_0098771) SubClassOf [chemical homeostasis](http://purl.obolibrary.org/obo/GO_0048878) + + + +### inorganic ion transmembrane transport `http://purl.obolibrary.org/obo/GO_0098660` +#### Removed +- [inorganic ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098660) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "transmembrane inorganic ion transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [inorganic ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098660) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [inorganic ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098660) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inorganic ion membrane transport" + +- [inorganic ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098660) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic ion transmembrane transport" + +- [inorganic ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098660) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The process in which an inorganic ion is transported across a membrane." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [inorganic ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098660) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0098660" + +- [inorganic ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098660) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Note that this term is not intended for use in annotating lateral movement within membranes." + +- Class: [inorganic ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098660) + +- [inorganic ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098660) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([results in transport across](http://purl.obolibrary.org/obo/RO_0002342) some [membrane](http://purl.obolibrary.org/obo/GO_0016020)) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [inorganic ion](http://purl.obolibrary.org/obo/CHEBI_36914)) + +- [inorganic ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098660) SubClassOf [transmembrane transport](http://purl.obolibrary.org/obo/GO_0055085) + +- [inorganic ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098660) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [inorganic ion](http://purl.obolibrary.org/obo/CHEBI_36914) + + + +### inorganic molecular entity `http://purl.obolibrary.org/obo/CHEBI_24835` +#### Removed +- [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inorganic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anorganische Verbindungen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecular entity that contains no carbon." + +- [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24835" + +- [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inorganic molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic molecular entity" + +- [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inorganics" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inorganic entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) SubClassOf [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) + + + +### inorganic oxide `http://purl.obolibrary.org/obo/CHEBI_24836` +#### Removed +- [inorganic oxide](http://purl.obolibrary.org/obo/CHEBI_24836) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic oxide" + +- [inorganic oxide](http://purl.obolibrary.org/obo/CHEBI_24836) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inorganic oxides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic oxide](http://purl.obolibrary.org/obo/CHEBI_24836) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [inorganic oxide](http://purl.obolibrary.org/obo/CHEBI_24836) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [inorganic oxide](http://purl.obolibrary.org/obo/CHEBI_24836) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24836" + +- Class: [inorganic oxide](http://purl.obolibrary.org/obo/CHEBI_24836) + +- [inorganic oxide](http://purl.obolibrary.org/obo/CHEBI_24836) SubClassOf [oxide](http://purl.obolibrary.org/obo/CHEBI_25741) + +- [inorganic oxide](http://purl.obolibrary.org/obo/CHEBI_24836) SubClassOf [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) + + + +### inorganic radical `http://purl.obolibrary.org/obo/CHEBI_36871` +#### Removed +- [inorganic radical](http://purl.obolibrary.org/obo/CHEBI_36871) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inorganic radicals" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic radical](http://purl.obolibrary.org/obo/CHEBI_36871) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [inorganic radical](http://purl.obolibrary.org/obo/CHEBI_36871) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic radical" + +- [inorganic radical](http://purl.obolibrary.org/obo/CHEBI_36871) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [inorganic radical](http://purl.obolibrary.org/obo/CHEBI_36871) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36871" + +- Class: [inorganic radical](http://purl.obolibrary.org/obo/CHEBI_36871) + +- [inorganic radical](http://purl.obolibrary.org/obo/CHEBI_36871) SubClassOf [radical](http://purl.obolibrary.org/obo/CHEBI_26519) + +- [inorganic radical](http://purl.obolibrary.org/obo/CHEBI_36871) SubClassOf [inorganic molecular entity](http://purl.obolibrary.org/obo/CHEBI_24835) + + + +### inorganic radical anion `http://purl.obolibrary.org/obo/CHEBI_36876` +#### Removed +- [inorganic radical anion](http://purl.obolibrary.org/obo/CHEBI_36876) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic radical anion" + +- [inorganic radical anion](http://purl.obolibrary.org/obo/CHEBI_36876) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [inorganic radical anion](http://purl.obolibrary.org/obo/CHEBI_36876) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [inorganic radical anion](http://purl.obolibrary.org/obo/CHEBI_36876) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36876" + +- [inorganic radical anion](http://purl.obolibrary.org/obo/CHEBI_36876) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inorganic anion radical" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic radical anion](http://purl.obolibrary.org/obo/CHEBI_36876) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inorganic radical anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [inorganic radical anion](http://purl.obolibrary.org/obo/CHEBI_36876) + +- [inorganic radical anion](http://purl.obolibrary.org/obo/CHEBI_36876) SubClassOf [inorganic radical ion](http://purl.obolibrary.org/obo/CHEBI_36878) + +- [inorganic radical anion](http://purl.obolibrary.org/obo/CHEBI_36876) SubClassOf [radical anion](http://purl.obolibrary.org/obo/CHEBI_36873) + + + +### inorganic radical ion `http://purl.obolibrary.org/obo/CHEBI_36878` +#### Removed +- [inorganic radical ion](http://purl.obolibrary.org/obo/CHEBI_36878) [label](http://www.w3.org/2000/01/rdf-schema#label) "inorganic radical ion" + +- [inorganic radical ion](http://purl.obolibrary.org/obo/CHEBI_36878) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inorganic radical ions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic radical ion](http://purl.obolibrary.org/obo/CHEBI_36878) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inorganic ion radical" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [inorganic radical ion](http://purl.obolibrary.org/obo/CHEBI_36878) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [inorganic radical ion](http://purl.obolibrary.org/obo/CHEBI_36878) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36878" + +- [inorganic radical ion](http://purl.obolibrary.org/obo/CHEBI_36878) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [inorganic radical ion](http://purl.obolibrary.org/obo/CHEBI_36878) + +- [inorganic radical ion](http://purl.obolibrary.org/obo/CHEBI_36878) SubClassOf [radical ion](http://purl.obolibrary.org/obo/CHEBI_36875) + +- [inorganic radical ion](http://purl.obolibrary.org/obo/CHEBI_36878) SubClassOf [inorganic radical](http://purl.obolibrary.org/obo/CHEBI_36871) + + + +### input of `http://purl.obolibrary.org/obo/RO_0002352` +#### Removed +- [input of](http://purl.obolibrary.org/obo/RO_0002352) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [input of](http://purl.obolibrary.org/obo/RO_0002352) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### interaction relation helper property `http://purl.obolibrary.org/obo/RO_0002563` +#### Removed +- [interaction relation helper property](http://purl.obolibrary.org/obo/RO_0002563) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [interaction relation helper property](http://purl.obolibrary.org/obo/RO_0002563) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### interacts with `http://purl.obolibrary.org/obo/RO_0002434` +#### Removed +- [interacts with](http://purl.obolibrary.org/obo/RO_0002434) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [interacts with](http://purl.obolibrary.org/obo/RO_0002434) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### intermediate monocyte `http://purl.obolibrary.org/obo/CL_0002393` +#### Removed +- [intermediate monocyte](http://purl.obolibrary.org/obo/CL_0002393) EquivalentTo [monocyte](http://purl.obolibrary.org/obo/CL_0000576) and ([has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [monocyte differentiation](http://purl.obolibrary.org/obo/GO_0030224)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 2](http://purl.obolibrary.org/obo/PR_000001199)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) + +- [intermediate monocyte](http://purl.obolibrary.org/obo/CL_0002393) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [intermediate monocyte](http://purl.obolibrary.org/obo/CL_0002393) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [intermediate monocyte](http://purl.obolibrary.org/obo/CL_0002393) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [intermediate monocyte](http://purl.obolibrary.org/obo/CL_0002393) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 2](http://purl.obolibrary.org/obo/PR_000001199) + +- [intermediate monocyte](http://purl.obolibrary.org/obo/CL_0002393) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [monocyte differentiation](http://purl.obolibrary.org/obo/GO_0030224) + +#### Added +- [intermediate monocyte](http://purl.obolibrary.org/obo/CL_0002393) EquivalentTo [monocyte](http://purl.obolibrary.org/obo/CL_0000576) and ([has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [monocyte differentiation](http://purl.obolibrary.org/obo/GO_0030224)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 2](http://purl.obolibrary.org/obo/PR_000001199)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) + +- [intermediate monocyte](http://purl.obolibrary.org/obo/CL_0002393) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [intermediate monocyte](http://purl.obolibrary.org/obo/CL_0002393) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [monocyte differentiation](http://purl.obolibrary.org/obo/GO_0030224) + +- [intermediate monocyte](http://purl.obolibrary.org/obo/CL_0002393) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [intermediate monocyte](http://purl.obolibrary.org/obo/CL_0002393) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [intermediate monocyte](http://purl.obolibrary.org/obo/CL_0002393) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-C chemokine receptor type 2](http://purl.obolibrary.org/obo/PR_000001199) + + +### internodal tract myocyte `http://purl.obolibrary.org/obo/CL_0002096` + +#### Added +- [internodal tract myocyte](http://purl.obolibrary.org/obo/CL_0002096) SubClassOf [transversely striated visceral muscle cell](http://purl.obolibrary.org/obo/CL_0008009) + + +### interstitial cell `http://purl.obolibrary.org/obo/CL_4030031` +#### Removed +- [interstitial cell](http://purl.obolibrary.org/obo/CL_4030031) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### interstitial cell of Cajal `http://purl.obolibrary.org/obo/CL_0002088` +#### Removed +- [interstitial cell of Cajal](http://purl.obolibrary.org/obo/CL_0002088) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### intracellular calcium ion homeostasis `http://purl.obolibrary.org/obo/GO_0006874` +#### Removed +- [intracellular calcium ion homeostasis](http://purl.obolibrary.org/obo/GO_0006874) SubClassOf [calcium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055074) + +- [intracellular calcium ion homeostasis](http://purl.obolibrary.org/obo/GO_0006874) SubClassOf [intracellular monoatomic cation homeostasis](http://purl.obolibrary.org/obo/GO_0030003) + +#### Added +- [intracellular calcium ion homeostasis](http://purl.obolibrary.org/obo/GO_0006874) SubClassOf [cellular homeostasis](http://purl.obolibrary.org/obo/GO_0019725) + +- [intracellular calcium ion homeostasis](http://purl.obolibrary.org/obo/GO_0006874) SubClassOf [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [calcium(2+)](http://purl.obolibrary.org/obo/CHEBI_29108) + + +### intracellular glucose homeostasis `http://purl.obolibrary.org/obo/GO_0001678` +#### Removed +- [intracellular glucose homeostasis](http://purl.obolibrary.org/obo/GO_0001678) SubClassOf [glucose homeostasis](http://purl.obolibrary.org/obo/GO_0042593) + +- [intracellular glucose homeostasis](http://purl.obolibrary.org/obo/GO_0001678) SubClassOf [intracellular chemical homeostasis](http://purl.obolibrary.org/obo/GO_0055082) + +#### Added +- [intracellular glucose homeostasis](http://purl.obolibrary.org/obo/GO_0001678) SubClassOf [cellular homeostasis](http://purl.obolibrary.org/obo/GO_0019725) + +- [intracellular glucose homeostasis](http://purl.obolibrary.org/obo/GO_0001678) SubClassOf [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [glucose](http://purl.obolibrary.org/obo/CHEBI_17234) + + +### intracellular glutamate homeostasis `http://purl.obolibrary.org/obo/GO_0090461` +#### Removed +- [intracellular glutamate homeostasis](http://purl.obolibrary.org/obo/GO_0090461) SubClassOf [intracellular chemical homeostasis](http://purl.obolibrary.org/obo/GO_0055082) + +#### Added +- [intracellular glutamate homeostasis](http://purl.obolibrary.org/obo/GO_0090461) SubClassOf [cellular homeostasis](http://purl.obolibrary.org/obo/GO_0019725) + + +### intracellular iron ion homeostasis `http://purl.obolibrary.org/obo/GO_0006879` +#### Removed +- [intracellular iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0006879) SubClassOf [intracellular monoatomic cation homeostasis](http://purl.obolibrary.org/obo/GO_0030003) + +- [intracellular iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0006879) SubClassOf [iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0055072) + +#### Added +- [intracellular iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0006879) SubClassOf [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [iron cation](http://purl.obolibrary.org/obo/CHEBI_24875) + +- [intracellular iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0006879) SubClassOf [intracellular chemical homeostasis](http://purl.obolibrary.org/obo/GO_0055082) + + +### intracellular monoatomic cation homeostasis `http://purl.obolibrary.org/obo/GO_0030003` +#### Removed +- [intracellular monoatomic cation homeostasis](http://purl.obolibrary.org/obo/GO_0030003) SubClassOf [intracellular monoatomic ion homeostasis](http://purl.obolibrary.org/obo/GO_0006873) + +- [intracellular monoatomic cation homeostasis](http://purl.obolibrary.org/obo/GO_0030003) SubClassOf [monoatomic cation homeostasis](http://purl.obolibrary.org/obo/GO_0055080) + +#### Added +- [intracellular monoatomic cation homeostasis](http://purl.obolibrary.org/obo/GO_0030003) SubClassOf [cellular homeostasis](http://purl.obolibrary.org/obo/GO_0019725) + +- [intracellular monoatomic cation homeostasis](http://purl.obolibrary.org/obo/GO_0030003) SubClassOf [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [monoatomic cation](http://purl.obolibrary.org/obo/CHEBI_23906) + + +### intracellular monoatomic ion homeostasis `http://purl.obolibrary.org/obo/GO_0006873` +#### Removed +- [intracellular monoatomic ion homeostasis](http://purl.obolibrary.org/obo/GO_0006873) SubClassOf [intracellular chemical homeostasis](http://purl.obolibrary.org/obo/GO_0055082) + +- [intracellular monoatomic ion homeostasis](http://purl.obolibrary.org/obo/GO_0006873) SubClassOf [monoatomic ion homeostasis](http://purl.obolibrary.org/obo/GO_0050801) + +#### Added +- [intracellular monoatomic ion homeostasis](http://purl.obolibrary.org/obo/GO_0006873) SubClassOf [cellular homeostasis](http://purl.obolibrary.org/obo/GO_0019725) + +- [intracellular monoatomic ion homeostasis](http://purl.obolibrary.org/obo/GO_0006873) SubClassOf [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [monoatomic ion](http://purl.obolibrary.org/obo/CHEBI_24867) + + +### intracellular phosphate ion homeostasis `http://purl.obolibrary.org/obo/GO_0030643` +#### Removed +- [intracellular phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030643) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [intracellular phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030643) [label](http://www.w3.org/2000/01/rdf-schema#label) "intracellular phosphate ion homeostasis" + +- [intracellular phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030643) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular phosphate ion homeostasis" + +- [intracellular phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030643) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0030643" + +- [intracellular phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030643) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A homeostatic process involved in the maintenance of a steady state level of phosphate ions within a cell." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- Class: [intracellular phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030643) + +- [intracellular phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030643) EquivalentTo [cellular homeostasis](http://purl.obolibrary.org/obo/GO_0019725) and ([regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780)) + +- [intracellular phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030643) SubClassOf [phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055062) + +- [intracellular phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030643) SubClassOf [intracellular chemical homeostasis](http://purl.obolibrary.org/obo/GO_0055082) + + + +### intracellular sodium ion homeostasis `http://purl.obolibrary.org/obo/GO_0006883` +#### Removed +- [intracellular sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0006883) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular sodium ion homeostasis" + +- [intracellular sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0006883) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006883" + +- [intracellular sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0006883) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A homeostatic process involved in the maintenance of a steady state level of sodium ions within a cell." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [intracellular sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0006883) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [intracellular sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0006883) [label](http://www.w3.org/2000/01/rdf-schema#label) "intracellular sodium ion homeostasis" + +- Class: [intracellular sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0006883) + +- [intracellular sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0006883) EquivalentTo [intracellular chemical homeostasis](http://purl.obolibrary.org/obo/GO_0055082) and ([regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101)) + +- [intracellular sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0006883) SubClassOf [sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055078) + +- [intracellular sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0006883) SubClassOf [intracellular monoatomic cation homeostasis](http://purl.obolibrary.org/obo/GO_0030003) + + + +### intracellular sphingolipid homeostasis `http://purl.obolibrary.org/obo/GO_0090156` +#### Removed +- [intracellular sphingolipid homeostasis](http://purl.obolibrary.org/obo/GO_0090156) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tb" + +- [intracellular sphingolipid homeostasis](http://purl.obolibrary.org/obo/GO_0090156) [label](http://www.w3.org/2000/01/rdf-schema#label) "intracellular sphingolipid homeostasis" + +- [intracellular sphingolipid homeostasis](http://purl.obolibrary.org/obo/GO_0090156) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0090156" + +- [intracellular sphingolipid homeostasis](http://purl.obolibrary.org/obo/GO_0090156) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [intracellular sphingolipid homeostasis](http://purl.obolibrary.org/obo/GO_0090156) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular sphingolipid homeostasis" + +- [intracellular sphingolipid homeostasis](http://purl.obolibrary.org/obo/GO_0090156) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A homeostatic process involved in the maintenance of a steady state level of sphingolipids within a cell." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ascb_2009" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [intracellular sphingolipid homeostasis](http://purl.obolibrary.org/obo/GO_0090156) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2009-12-08T08:21:36Z" + +- Class: [intracellular sphingolipid homeostasis](http://purl.obolibrary.org/obo/GO_0090156) + +- [intracellular sphingolipid homeostasis](http://purl.obolibrary.org/obo/GO_0090156) EquivalentTo [cellular homeostasis](http://purl.obolibrary.org/obo/GO_0019725) and ([regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739)) + +- [intracellular sphingolipid homeostasis](http://purl.obolibrary.org/obo/GO_0090156) SubClassOf [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739) + +- [intracellular sphingolipid homeostasis](http://purl.obolibrary.org/obo/GO_0090156) SubClassOf [lipid homeostasis](http://purl.obolibrary.org/obo/GO_0055088) + +- [intracellular sphingolipid homeostasis](http://purl.obolibrary.org/obo/GO_0090156) SubClassOf [intracellular chemical homeostasis](http://purl.obolibrary.org/obo/GO_0055082) + + + +### intracellular sulfate ion homeostasis `http://purl.obolibrary.org/obo/GO_0030642` +#### Removed +- [intracellular sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030642) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular sulfate ion homeostasis" + +- [intracellular sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030642) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "sulphate ion homeostasis" + +- [intracellular sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030642) [label](http://www.w3.org/2000/01/rdf-schema#label) "intracellular sulfate ion homeostasis" + +- [intracellular sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030642) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0030642" + +- [intracellular sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030642) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [intracellular sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030642) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A homeostatic process involved in the maintenance of a steady state level of sulfate ions within a cell." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- Class: [intracellular sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030642) + +- [intracellular sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030642) EquivalentTo [intracellular chemical homeostasis](http://purl.obolibrary.org/obo/GO_0055082) and ([regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189)) + +- [intracellular sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030642) SubClassOf [sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055063) + +- [intracellular sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0030642) SubClassOf [intracellular chemical homeostasis](http://purl.obolibrary.org/obo/GO_0055082) + + + +### intracellular water homeostasis `http://purl.obolibrary.org/obo/GO_0009992` +#### Removed +- [intracellular water homeostasis](http://purl.obolibrary.org/obo/GO_0009992) SubClassOf [water homeostasis](http://purl.obolibrary.org/obo/GO_0030104) + +- [intracellular water homeostasis](http://purl.obolibrary.org/obo/GO_0009992) SubClassOf [intracellular chemical homeostasis](http://purl.obolibrary.org/obo/GO_0055082) + +#### Added +- [intracellular water homeostasis](http://purl.obolibrary.org/obo/GO_0009992) SubClassOf [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [water](http://purl.obolibrary.org/obo/CHEBI_15377) + + +### involved in `http://purl.obolibrary.org/obo/RO_0002331` +#### Removed +- [involved in](http://purl.obolibrary.org/obo/RO_0002331) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [involved in](http://purl.obolibrary.org/obo/RO_0002331) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### involved in negative regulation of `http://purl.obolibrary.org/obo/RO_0002430` +#### Removed +- [involved in negative regulation of](http://purl.obolibrary.org/obo/RO_0002430) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [involved in negative regulation of](http://purl.obolibrary.org/obo/RO_0002430) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### involved in or involved in regulation of `http://purl.obolibrary.org/obo/RO_0002431` +#### Removed +- [involved in or involved in regulation of](http://purl.obolibrary.org/obo/RO_0002431) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [involved in or involved in regulation of](http://purl.obolibrary.org/obo/RO_0002431) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### involved in positive regulation of `http://purl.obolibrary.org/obo/RO_0002429` +#### Removed +- [involved in positive regulation of](http://purl.obolibrary.org/obo/RO_0002429) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [involved in positive regulation of](http://purl.obolibrary.org/obo/RO_0002429) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### involved in regulation of `http://purl.obolibrary.org/obo/RO_0002428` +#### Removed +- [involved in regulation of](http://purl.obolibrary.org/obo/RO_0002428) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [involved in regulation of](http://purl.obolibrary.org/obo/RO_0002428) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### ion `http://purl.obolibrary.org/obo/CHEBI_24870` +#### Removed +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24870" + +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ionen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "iones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecular entity having a net electric charge." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ionen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) [label](http://www.w3.org/2000/01/rdf-schema#label) "ion" + +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "iones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [ion](http://purl.obolibrary.org/obo/CHEBI_24870) + +- [ion](http://purl.obolibrary.org/obo/CHEBI_24870) SubClassOf [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) + + + +### ion binding `http://purl.obolibrary.org/obo/GO_0043167` +#### Removed +- [ion binding](http://purl.obolibrary.org/obo/GO_0043167) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0043167" + +- [ion binding](http://purl.obolibrary.org/obo/GO_0043167) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_chembl](http://purl.obolibrary.org/obo/go#goslim_chembl) + +- [ion binding](http://purl.obolibrary.org/obo/GO_0043167) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_pir](http://purl.obolibrary.org/obo/go#goslim_pir) + +- [ion binding](http://purl.obolibrary.org/obo/GO_0043167) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_yeast](http://purl.obolibrary.org/obo/go#goslim_yeast) + +- [ion binding](http://purl.obolibrary.org/obo/GO_0043167) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_metagenomics](http://purl.obolibrary.org/obo/go#goslim_metagenomics) + +- [ion binding](http://purl.obolibrary.org/obo/GO_0043167) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to an ion, a charged atoms or groups of atoms." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [ion binding](http://purl.obolibrary.org/obo/GO_0043167) [label](http://www.w3.org/2000/01/rdf-schema#label) "ion binding" + +- [ion binding](http://purl.obolibrary.org/obo/GO_0043167) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [ion binding](http://purl.obolibrary.org/obo/GO_0043167) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "atom binding" + +- Class: [ion binding](http://purl.obolibrary.org/obo/GO_0043167) + +- [ion binding](http://purl.obolibrary.org/obo/GO_0043167) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [ion](http://purl.obolibrary.org/obo/CHEBI_24870)) + +- [ion binding](http://purl.obolibrary.org/obo/GO_0043167) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [ion](http://purl.obolibrary.org/obo/CHEBI_24870) + +- [ion binding](http://purl.obolibrary.org/obo/GO_0043167) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + + +### ionic macromolecule `http://purl.obolibrary.org/obo/CHEBI_53368` +#### Removed +- [ionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53368) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A macromolecule containing ionic groups." + +- [ionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53368) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polyionic macromolecule" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53368) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [ionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53368) [label](http://www.w3.org/2000/01/rdf-schema#label) "ionic macromolecule" + +- [ionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53368) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:53368" + +- [ionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53368) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ionic polymer" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53368) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [ionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53368) + +- [ionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53368) SubClassOf [macromolecule](http://purl.obolibrary.org/obo/CHEBI_33839) + + + +### ionic polymer `http://purl.obolibrary.org/obo/CHEBI_60164` +#### Removed +- [ionic polymer](http://purl.obolibrary.org/obo/CHEBI_60164) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polyionic polymer" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ionic polymer](http://purl.obolibrary.org/obo/CHEBI_60164) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:60164" + +- [ionic polymer](http://purl.obolibrary.org/obo/CHEBI_60164) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An ionic polymer is a polymer, composed of ionic macromolecules." + +- [ionic polymer](http://purl.obolibrary.org/obo/CHEBI_60164) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [ionic polymer](http://purl.obolibrary.org/obo/CHEBI_60164) [label](http://www.w3.org/2000/01/rdf-schema#label) "ionic polymer" + +- [ionic polymer](http://purl.obolibrary.org/obo/CHEBI_60164) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [ionic polymer](http://purl.obolibrary.org/obo/CHEBI_60164) + +- [ionic polymer](http://purl.obolibrary.org/obo/CHEBI_60164) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [ionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53368) + +- [ionic polymer](http://purl.obolibrary.org/obo/CHEBI_60164) SubClassOf [polymer](http://purl.obolibrary.org/obo/CHEBI_60027) + + + +### iron atom `http://purl.obolibrary.org/obo/CHEBI_18248` +#### Removed +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB01592" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7439-89-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "26Fe" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [formula](http://purl.obolibrary.org/obo/chebi/formula) "Fe" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WebElements:Fe" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:4122945" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/Fe" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7439-89-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "iron" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "iron" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [mass](http://purl.obolibrary.org/obo/chebi/mass) "55.84500" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[Fe]" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ferrum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [label](http://www.w3.org/2000/01/rdf-schema#label) "iron atom" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:18248" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00023" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Iron" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Eisen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13322" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An iron group element atom that has atomic number 26." + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Fe" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "55.93494" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fer" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0015531" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "XEEYBQQBJWHFJM-UHFFFAOYSA-N" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24872" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hierro" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7439-89-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Fe" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5974" + +- Class: [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [micronutrient](http://purl.obolibrary.org/obo/CHEBI_27027) + +- [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) SubClassOf [iron group element atom](http://purl.obolibrary.org/obo/CHEBI_33356) + + + +### iron cation `http://purl.obolibrary.org/obo/CHEBI_24875` +#### Removed +- [iron cation](http://purl.obolibrary.org/obo/CHEBI_24875) [formula](http://purl.obolibrary.org/obo/chebi/formula) "Fe" + +- [iron cation](http://purl.obolibrary.org/obo/CHEBI_24875) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [iron cation](http://purl.obolibrary.org/obo/CHEBI_24875) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [iron cation](http://purl.obolibrary.org/obo/CHEBI_24875) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24875" + +- [iron cation](http://purl.obolibrary.org/obo/CHEBI_24875) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "55.93494" + +- [iron cation](http://purl.obolibrary.org/obo/CHEBI_24875) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "iron cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [iron cation](http://purl.obolibrary.org/obo/CHEBI_24875) [mass](http://purl.obolibrary.org/obo/chebi/mass) "55.845" + +- [iron cation](http://purl.obolibrary.org/obo/CHEBI_24875) [label](http://www.w3.org/2000/01/rdf-schema#label) "iron cation" + +- [iron cation](http://purl.obolibrary.org/obo/CHEBI_24875) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "iron cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [iron cation](http://purl.obolibrary.org/obo/CHEBI_24875) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Fe cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [iron cation](http://purl.obolibrary.org/obo/CHEBI_24875) SubClassOf [transition element cation](http://purl.obolibrary.org/obo/CHEBI_33515) + +- [iron cation](http://purl.obolibrary.org/obo/CHEBI_24875) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [cofactor](http://purl.obolibrary.org/obo/CHEBI_23357) + +- [iron cation](http://purl.obolibrary.org/obo/CHEBI_24875) SubClassOf [elemental iron](http://purl.obolibrary.org/obo/CHEBI_82663) + + + +### iron group element atom `http://purl.obolibrary.org/obo/CHEBI_33356` +#### Removed +- [iron group element atom](http://purl.obolibrary.org/obo/CHEBI_33356) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "group 8 elements" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [iron group element atom](http://purl.obolibrary.org/obo/CHEBI_33356) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [iron group element atom](http://purl.obolibrary.org/obo/CHEBI_33356) [label](http://www.w3.org/2000/01/rdf-schema#label) "iron group element atom" + +- [iron group element atom](http://purl.obolibrary.org/obo/CHEBI_33356) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "iron group element" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [iron group element atom](http://purl.obolibrary.org/obo/CHEBI_33356) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33356" + +- [iron group element atom](http://purl.obolibrary.org/obo/CHEBI_33356) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "iron group elements" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [iron group element atom](http://purl.obolibrary.org/obo/CHEBI_33356) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [iron group element atom](http://purl.obolibrary.org/obo/CHEBI_33356) + +- [iron group element atom](http://purl.obolibrary.org/obo/CHEBI_33356) SubClassOf [d-block element atom](http://purl.obolibrary.org/obo/CHEBI_33561) + + + +### iron group molecular entity `http://purl.obolibrary.org/obo/CHEBI_33744` +#### Removed +- [iron group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33744) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33744" + +- [iron group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33744) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "iron group molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [iron group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33744) [label](http://www.w3.org/2000/01/rdf-schema#label) "iron group molecular entity" + +- [iron group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33744) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [iron group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33744) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [iron group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33744) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "iron group molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [iron group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33744) + +- [iron group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33744) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [iron group element atom](http://purl.obolibrary.org/obo/CHEBI_33356) + +- [iron group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33744) SubClassOf [d-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33676) + + + +### iron import into cell `http://purl.obolibrary.org/obo/GO_0033212` +#### Removed +- [iron import into cell](http://purl.obolibrary.org/obo/GO_0033212) SubClassOf [import into cell](http://purl.obolibrary.org/obo/GO_0098657) + +#### Added +- [iron import into cell](http://purl.obolibrary.org/obo/GO_0033212) SubClassOf [has target end location](http://purl.obolibrary.org/obo/RO_0002339) some [intracellular anatomical structure](http://purl.obolibrary.org/obo/GO_0005622) + +- [iron import into cell](http://purl.obolibrary.org/obo/GO_0033212) SubClassOf [has target start location](http://purl.obolibrary.org/obo/RO_0002338) some [extracellular region](http://purl.obolibrary.org/obo/GO_0005576) + + +### iron ion binding `http://purl.obolibrary.org/obo/GO_0005506` +#### Removed +- [iron ion binding](http://purl.obolibrary.org/obo/GO_0005506) SubClassOf [transition metal ion binding](http://purl.obolibrary.org/obo/GO_0046914) + +#### Added +- [iron ion binding](http://purl.obolibrary.org/obo/GO_0005506) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### iron ion homeostasis `http://purl.obolibrary.org/obo/GO_0055072` +#### Removed +- [iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0055072) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0055072) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "iron homeostasis" + +- [iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0055072) [label](http://www.w3.org/2000/01/rdf-schema#label) "iron ion homeostasis" + +- [iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0055072) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0055072" + +- [iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0055072) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jid" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- Class: [iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0055072) + +- [iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0055072) EquivalentTo [chemical homeostasis](http://purl.obolibrary.org/obo/GO_0048878) and ([regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [iron cation](http://purl.obolibrary.org/obo/CHEBI_24875)) + +- [iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0055072) SubClassOf [monoatomic cation homeostasis](http://purl.obolibrary.org/obo/GO_0055080) + +- [iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0055072) SubClassOf [inorganic ion homeostasis](http://purl.obolibrary.org/obo/GO_0098771) + +- [iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0055072) SubClassOf [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [iron cation](http://purl.obolibrary.org/obo/CHEBI_24875) + + + +### iron ion transmembrane transport `http://purl.obolibrary.org/obo/GO_0034755` +#### Removed +- [iron ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0034755) SubClassOf [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) + +- [iron ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0034755) SubClassOf [monoatomic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098655) + +#### Added +- [iron ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0034755) SubClassOf [transmembrane transport](http://purl.obolibrary.org/obo/GO_0055085) + + +### iron ion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0005381` +#### Removed +- [iron ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005381) SubClassOf [transition metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046915) + +#### Added +- [iron ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005381) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + +### iron ion transport `http://purl.obolibrary.org/obo/GO_0006826` +#### Removed +- [iron ion transport](http://purl.obolibrary.org/obo/GO_0006826) SubClassOf [transition metal ion transport](http://purl.obolibrary.org/obo/GO_0000041) + +#### Added +- [iron ion transport](http://purl.obolibrary.org/obo/GO_0006826) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### iron molecular entity `http://purl.obolibrary.org/obo/CHEBI_24873` +#### Removed +- [iron molecular entity](http://purl.obolibrary.org/obo/CHEBI_24873) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "iron molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [iron molecular entity](http://purl.obolibrary.org/obo/CHEBI_24873) [label](http://www.w3.org/2000/01/rdf-schema#label) "iron molecular entity" + +- [iron molecular entity](http://purl.obolibrary.org/obo/CHEBI_24873) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [iron molecular entity](http://purl.obolibrary.org/obo/CHEBI_24873) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "iron molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [iron molecular entity](http://purl.obolibrary.org/obo/CHEBI_24873) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24873" + +- [iron molecular entity](http://purl.obolibrary.org/obo/CHEBI_24873) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [iron molecular entity](http://purl.obolibrary.org/obo/CHEBI_24873) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "iron compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [iron molecular entity](http://purl.obolibrary.org/obo/CHEBI_24873) + +- [iron molecular entity](http://purl.obolibrary.org/obo/CHEBI_24873) SubClassOf [iron group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33744) + +- [iron molecular entity](http://purl.obolibrary.org/obo/CHEBI_24873) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [iron atom](http://purl.obolibrary.org/obo/CHEBI_18248) + + + +### is active in `http://purl.obolibrary.org/obo/RO_0002432` +#### Removed +- [is active in](http://purl.obolibrary.org/obo/RO_0002432) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [is active in](http://purl.obolibrary.org/obo/RO_0002432) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### is kinase activity `http://purl.obolibrary.org/obo/RO_0002481` +#### Removed +- [is kinase activity](http://purl.obolibrary.org/obo/RO_0002481) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [is kinase activity](http://purl.obolibrary.org/obo/RO_0002481) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### is negative form of `http://purl.obolibrary.org/obo/RO_0004050` +#### Removed +- [is negative form of](http://purl.obolibrary.org/obo/RO_0004050) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "cjm" + +#### Added +- [is negative form of](http://purl.obolibrary.org/obo/RO_0004050) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### is_conjugate_acid_of `http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of` +#### Removed +- ObjectProperty: [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) + + + +### is_conjugate_base_of `http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of` +#### Removed +- ObjectProperty: [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) + + + +### is_enantiomer_of `http://purl.obolibrary.org/obo/chebi#is_enantiomer_of` +#### Removed +- ObjectProperty: [is_enantiomer_of](http://purl.obolibrary.org/obo/chebi#is_enantiomer_of) + + + +### is_substituent_group_from `http://purl.obolibrary.org/obo/chebi#is_substituent_group_from` +#### Removed +- ObjectProperty: [is_substituent_group_from](http://purl.obolibrary.org/obo/chebi#is_substituent_group_from) + + + +### is_tautomer_of `http://purl.obolibrary.org/obo/chebi#is_tautomer_of` +#### Removed +- ObjectProperty: [is_tautomer_of](http://purl.obolibrary.org/obo/chebi#is_tautomer_of) + + + +### isoprenoid `http://purl.obolibrary.org/obo/CHEBI_24913` +#### Removed +- [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12769708" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LIPID_MAPS_class:LMPR01" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "LIPID MAPS" + +- [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) [label](http://www.w3.org/2000/01/rdf-schema#label) "isoprenoid" + +- [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "isoprenoids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24913" + +- [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "isoprenoid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19219049" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives." + +- [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "isoprenoids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- Class: [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) + +- [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) SubClassOf [lipid](http://purl.obolibrary.org/obo/CHEBI_18059) + + + +### isoprenoid binding `http://purl.obolibrary.org/obo/GO_0019840` +#### Removed +- [isoprenoid binding](http://purl.obolibrary.org/obo/GO_0019840) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_pir](http://purl.obolibrary.org/obo/go#goslim_pir) + +- [isoprenoid binding](http://purl.obolibrary.org/obo/GO_0019840) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [isoprenoid binding](http://purl.obolibrary.org/obo/GO_0019840) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [isoprenoid binding](http://purl.obolibrary.org/obo/GO_0019840) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0019840" + +- [isoprenoid binding](http://purl.obolibrary.org/obo/GO_0019840) [label](http://www.w3.org/2000/01/rdf-schema#label) "isoprenoid binding" + +- Class: [isoprenoid binding](http://purl.obolibrary.org/obo/GO_0019840) + +- [isoprenoid binding](http://purl.obolibrary.org/obo/GO_0019840) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913)) + +- [isoprenoid binding](http://purl.obolibrary.org/obo/GO_0019840) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) + +- [isoprenoid binding](http://purl.obolibrary.org/obo/GO_0019840) SubClassOf [lipid binding](http://purl.obolibrary.org/obo/GO_0008289) + + + +### isoprenoid biosynthetic process `http://purl.obolibrary.org/obo/GO_0008299` +#### Removed +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "polyisoprenoid anabolism" + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "isoprenoid biosynthesis" + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "polyterpene biosynthesis" + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "polyisoprenoid formation" + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "polyisoprenoid synthesis" + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) [label](http://www.w3.org/2000/01/rdf-schema#label) "isoprenoid biosynthetic process" + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0009241" + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "isoprenoid synthesis" + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "polyisoprenoid biosynthetic process" + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "isoprenoid formation" + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "polyisoprenoid biosynthesis" + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0008299" + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "polyterpene biosynthetic process" + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "isoprenoid anabolism" + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:POLYISOPRENSYN-PWY" + +- Class: [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913)) + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) SubClassOf [lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008610) + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) SubClassOf [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) + +- [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) SubClassOf [cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0044249) + + + +### isoprenoid catabolic process `http://purl.obolibrary.org/obo/GO_0008300` +#### Removed +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "polyisoprenoid catabolism" + +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "isoprenoid breakdown" + +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "polyterpene catabolism" + +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "polyisoprenoid catabolic process" + +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "polyisoprenoid degradation" + +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0008300" + +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0016097" + +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "isoprenoid degradation" + +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "isoprenoid catabolism" + +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "polyterpene catabolic process" + +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) [label](http://www.w3.org/2000/01/rdf-schema#label) "isoprenoid catabolic process" + +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "polyisoprenoid breakdown" + +- Class: [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) + +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913)) + +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) + +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) SubClassOf [cellular lipid catabolic process](http://purl.obolibrary.org/obo/GO_0044242) + +- [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) SubClassOf [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) + + + +### isoprenoid metabolic process `http://purl.obolibrary.org/obo/GO_0006720` +#### Removed +- [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "polyisoprenoid metabolism" + +- [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "polyterpene metabolic process" + +- [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "polyisoprenoid metabolic process" + +- [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0016096" + +- [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006720" + +- [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "polyterpene metabolism" + +- [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "isoprenoid metabolism" + +- [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198547684" + +- [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) [label](http://www.w3.org/2000/01/rdf-schema#label) "isoprenoid metabolic process" + +- Class: [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) + +- [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913)) + +- [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) + +- [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) SubClassOf [cellular lipid metabolic process](http://purl.obolibrary.org/obo/GO_0044255) + + + +### isoprenoid transport `http://purl.obolibrary.org/obo/GO_0046864` +#### Removed +- [isoprenoid transport](http://purl.obolibrary.org/obo/GO_0046864) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [isoprenoid transport](http://purl.obolibrary.org/obo/GO_0046864) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of isoprenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Isoprenoids comprise a group of compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [isoprenoid transport](http://purl.obolibrary.org/obo/GO_0046864) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046864" + +- [isoprenoid transport](http://purl.obolibrary.org/obo/GO_0046864) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_pir](http://purl.obolibrary.org/obo/go#goslim_pir) + +- [isoprenoid transport](http://purl.obolibrary.org/obo/GO_0046864) [label](http://www.w3.org/2000/01/rdf-schema#label) "isoprenoid transport" + +- Class: [isoprenoid transport](http://purl.obolibrary.org/obo/GO_0046864) + +- [isoprenoid transport](http://purl.obolibrary.org/obo/GO_0046864) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913)) + +- [isoprenoid transport](http://purl.obolibrary.org/obo/GO_0046864) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) + +- [isoprenoid transport](http://purl.obolibrary.org/obo/GO_0046864) SubClassOf [lipid transport](http://purl.obolibrary.org/obo/GO_0006869) + + + +### juvenile hormone `http://purl.obolibrary.org/obo/CHEBI_24943` +#### Removed +- [juvenile hormone](http://purl.obolibrary.org/obo/CHEBI_24943) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24943" + +- [juvenile hormone](http://purl.obolibrary.org/obo/CHEBI_24943) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Juvenile_hormone" + +- [juvenile hormone](http://purl.obolibrary.org/obo/CHEBI_24943) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A family of farnesane sesquiterpenoids that regulate many aspects of insect physiology." + +- [juvenile hormone](http://purl.obolibrary.org/obo/CHEBI_24943) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [juvenile hormone](http://purl.obolibrary.org/obo/CHEBI_24943) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [juvenile hormone](http://purl.obolibrary.org/obo/CHEBI_24943) [label](http://www.w3.org/2000/01/rdf-schema#label) "juvenile hormone" + +- [juvenile hormone](http://purl.obolibrary.org/obo/CHEBI_24943) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [animal metabolite](http://purl.obolibrary.org/obo/CHEBI_75767) + +- [juvenile hormone](http://purl.obolibrary.org/obo/CHEBI_24943) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [hormone](http://purl.obolibrary.org/obo/CHEBI_24621) + +- [juvenile hormone](http://purl.obolibrary.org/obo/CHEBI_24943) SubClassOf [farnesane sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_36757) + + + +### juvenile hormone binding `http://purl.obolibrary.org/obo/GO_0005500` +#### Removed +- [juvenile hormone binding](http://purl.obolibrary.org/obo/GO_0005500) SubClassOf [isoprenoid binding](http://purl.obolibrary.org/obo/GO_0019840) + + + +### juvenile hormone biosynthetic process `http://purl.obolibrary.org/obo/GO_0006718` +#### Removed +- [juvenile hormone biosynthetic process](http://purl.obolibrary.org/obo/GO_0006718) SubClassOf [sesquiterpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016106) + +#### Added +- [juvenile hormone biosynthetic process](http://purl.obolibrary.org/obo/GO_0006718) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### juvenile hormone catabolic process `http://purl.obolibrary.org/obo/GO_0006719` +#### Removed +- [juvenile hormone catabolic process](http://purl.obolibrary.org/obo/GO_0006719) SubClassOf [sesquiterpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016107) + + + +### juvenile hormone metabolic process `http://purl.obolibrary.org/obo/GO_0006716` +#### Removed +- [juvenile hormone metabolic process](http://purl.obolibrary.org/obo/GO_0006716) SubClassOf [sesquiterpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006714) + +#### Added +- [juvenile hormone metabolic process](http://purl.obolibrary.org/obo/GO_0006716) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### juvenile hormone secreting cell `http://purl.obolibrary.org/obo/CL_0000482` +#### Removed +- [juvenile hormone secreting cell](http://purl.obolibrary.org/obo/CL_0000482) SubClassOf [endocrine cell](http://purl.obolibrary.org/obo/CL_0000163) + +#### Added +- [juvenile hormone secreting cell](http://purl.obolibrary.org/obo/CL_0000482) SubClassOf [secretory cell](http://purl.obolibrary.org/obo/CL_0000151) + + +### juvenile hormone secretion `http://purl.obolibrary.org/obo/GO_0045443` +#### Removed +- [juvenile hormone secretion](http://purl.obolibrary.org/obo/GO_0045443) SubClassOf [terpenoid transport](http://purl.obolibrary.org/obo/GO_0046865) + +- [juvenile hormone secretion](http://purl.obolibrary.org/obo/GO_0045443) SubClassOf [lipid export from cell](http://purl.obolibrary.org/obo/GO_0140353) + + + +### juxtaglomerular apparatus `http://purl.obolibrary.org/obo/UBERON_0002303` + +#### Added +- [juxtaglomerular apparatus](http://purl.obolibrary.org/obo/UBERON_0002303) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [juxtaglomerular apparatus](http://purl.obolibrary.org/obo/UBERON_0002303) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + +### keratan `http://purl.obolibrary.org/obo/CHEBI_29057` +#### Removed +- [keratan](http://purl.obolibrary.org/obo/CHEBI_29057) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#1_STAR) + +- [keratan](http://purl.obolibrary.org/obo/CHEBI_29057) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14490" + +- [keratan](http://purl.obolibrary.org/obo/CHEBI_29057) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24954" + +- [keratan](http://purl.obolibrary.org/obo/CHEBI_29057) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:29057" + +- [keratan](http://purl.obolibrary.org/obo/CHEBI_29057) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [keratan](http://purl.obolibrary.org/obo/CHEBI_29057) [label](http://www.w3.org/2000/01/rdf-schema#label) "keratan" + +- Class: [keratan](http://purl.obolibrary.org/obo/CHEBI_29057) + +- [keratan](http://purl.obolibrary.org/obo/CHEBI_29057) SubClassOf [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) + + + +### keratan sulfate `http://purl.obolibrary.org/obo/CHEBI_60924` +#### Removed +- [keratan sulfate](http://purl.obolibrary.org/obo/CHEBI_60924) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "keratosulfate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "SUBMITTER" + +- [keratan sulfate](http://purl.obolibrary.org/obo/CHEBI_60924) [label](http://www.w3.org/2000/01/rdf-schema#label) "keratan sulfate" + +- [keratan sulfate](http://purl.obolibrary.org/obo/CHEBI_60924) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "keratan sulfates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [keratan sulfate](http://purl.obolibrary.org/obo/CHEBI_60924) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [keratan sulfate](http://purl.obolibrary.org/obo/CHEBI_60924) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A sulfated glycosaminoglycan, a linear polymer that consists of the repeating disaccharide [3)-beta-Gal-(1->4)-beta-GlcNAc-(1->] and containing sulfo groups located at random positions." + +- [keratan sulfate](http://purl.obolibrary.org/obo/CHEBI_60924) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:60924" + +- [keratan sulfate](http://purl.obolibrary.org/obo/CHEBI_60924) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [keratan sulfate](http://purl.obolibrary.org/obo/CHEBI_60924) SubClassOf [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) + +- [keratan sulfate](http://purl.obolibrary.org/obo/CHEBI_60924) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [keratan](http://purl.obolibrary.org/obo/CHEBI_29057) + +- [keratan sulfate](http://purl.obolibrary.org/obo/CHEBI_60924) SubClassOf [sulfated glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_35722) + + + +### keratan sulfate biosynthetic process `http://purl.obolibrary.org/obo/GO_0018146` +#### Removed +- [keratan sulfate biosynthetic process](http://purl.obolibrary.org/obo/GO_0018146) SubClassOf [glycosaminoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0006024) + +- [keratan sulfate biosynthetic process](http://purl.obolibrary.org/obo/GO_0018146) SubClassOf [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) + +#### Added +- [keratan sulfate biosynthetic process](http://purl.obolibrary.org/obo/GO_0018146) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### keratan sulfate catabolic process `http://purl.obolibrary.org/obo/GO_0042340` +#### Removed +- [keratan sulfate catabolic process](http://purl.obolibrary.org/obo/GO_0042340) SubClassOf [glycosaminoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0006027) + +- [keratan sulfate catabolic process](http://purl.obolibrary.org/obo/GO_0042340) SubClassOf [sulfur compound catabolic process](http://purl.obolibrary.org/obo/GO_0044273) + +#### Added +- [keratan sulfate catabolic process](http://purl.obolibrary.org/obo/GO_0042340) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### keratan sulfate metabolic process `http://purl.obolibrary.org/obo/GO_0042339` +#### Removed +- [keratan sulfate metabolic process](http://purl.obolibrary.org/obo/GO_0042339) SubClassOf [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) + +- [keratan sulfate metabolic process](http://purl.obolibrary.org/obo/GO_0042339) SubClassOf [mucopolysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903510) + +#### Added +- [keratan sulfate metabolic process](http://purl.obolibrary.org/obo/GO_0042339) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### keratinocyte `http://purl.obolibrary.org/obo/CL_0000312` +#### Removed +- [keratinocyte](http://purl.obolibrary.org/obo/CL_0000312) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0002185" + +- [keratinocyte](http://purl.obolibrary.org/obo/CL_0000312) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### ketone `http://purl.obolibrary.org/obo/CHEBI_17087` +#### Removed +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cetone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13427" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ketone" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ketones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13646" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ketones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24974" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "27.99491" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01450" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a ketone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:6127" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "R-CO-R'" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:17087" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Ketone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [mass](http://purl.obolibrary.org/obo/chebi/mass) "28.010" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:8742" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Keton" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [formula](http://purl.obolibrary.org/obo/chebi/formula) "COR2" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[*]C([*])=O" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H)." + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [label](http://www.w3.org/2000/01/rdf-schema#label) "ketone" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) SubClassOf [carbonyl compound](http://purl.obolibrary.org/obo/CHEBI_36586) + + + +### ketone catabolic process `http://purl.obolibrary.org/obo/GO_0042182` +#### Removed +- [ketone catabolic process](http://purl.obolibrary.org/obo/GO_0042182) SubClassOf [organic substance catabolic process](http://purl.obolibrary.org/obo/GO_1901575) + + + +### kidney blood vessel `http://purl.obolibrary.org/obo/UBERON_0003517` + +#### Added +- [kidney blood vessel](http://purl.obolibrary.org/obo/UBERON_0003517) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + +- [kidney blood vessel](http://purl.obolibrary.org/obo/UBERON_0003517) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + + +### kidney capillary `http://purl.obolibrary.org/obo/UBERON_0003527` + +#### Added +- [kidney capillary](http://purl.obolibrary.org/obo/UBERON_0003527) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [kidney capillary](http://purl.obolibrary.org/obo/UBERON_0003527) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + +### kidney cell `http://purl.obolibrary.org/obo/CL_1000497` +#### Removed +- [kidney cell](http://purl.obolibrary.org/obo/CL_1000497) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### kidney granular cell `http://purl.obolibrary.org/obo/CL_0000648` +#### Removed +- [kidney granular cell](http://purl.obolibrary.org/obo/CL_0000648) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000461" + + + +### kidney mesenchyme `http://purl.obolibrary.org/obo/UBERON_0003918` +#### Removed +- [kidney mesenchyme](http://purl.obolibrary.org/obo/UBERON_0003918) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [kidney mesenchyme](http://purl.obolibrary.org/obo/UBERON_0003918) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + + +### lacks_part `http://purl.obolibrary.org/obo/cl#lacks_part` +#### Removed +- [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) [label](http://www.w3.org/2000/01/rdf-schema#label) "lacks_part" + +- [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) [expand expression to](http://purl.obolibrary.org/obo/IAO_0000424) "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y" + +- ObjectProperty: [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) + + + +### lacks_part `http://purl.obolibrary.org/obo/CL_4030045` + +#### Added +- [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) [expand expression to](http://purl.obolibrary.org/obo/IAO_0000424) "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y" + +- [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) [label](http://www.w3.org/2000/01/rdf-schema#label) "lacks_part" + +- ObjectProperty: [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) + + +### lacks_part `http://purl.obolibrary.org/obo/pr#lacks_part` +#### Removed +- ObjectProperty: [lacks_part](http://purl.obolibrary.org/obo/pr#lacks_part) + + + +### lacks_plasma_membrane_part `http://purl.obolibrary.org/obo/CL_4030046` + +#### Added +- [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) [expand expression to](http://purl.obolibrary.org/obo/IAO_0000424) "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)" + +- [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) [label](http://www.w3.org/2000/01/rdf-schema#label) "lacks_plasma_membrane_part" + +- ObjectProperty: [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) + + +### lacks_plasma_membrane_part `http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part` +#### Removed +- [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) [expand expression to](http://purl.obolibrary.org/obo/IAO_0000424) "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)" + +- [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) [label](http://www.w3.org/2000/01/rdf-schema#label) "lacks_plasma_membrane_part" + +- ObjectProperty: [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) + + + +### langerin-negative dermal dendritic cell `http://purl.obolibrary.org/obo/CL_0002459` +#### Removed +- [langerin-negative dermal dendritic cell](http://purl.obolibrary.org/obo/CL_0002459) EquivalentTo [dermal dendritic cell](http://purl.obolibrary.org/obo/CL_0001006) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010)) + +- [langerin-negative dermal dendritic cell](http://purl.obolibrary.org/obo/CL_0002459) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010) + +#### Added +- [langerin-negative dermal dendritic cell](http://purl.obolibrary.org/obo/CL_0002459) EquivalentTo [dermal dendritic cell](http://purl.obolibrary.org/obo/CL_0001006) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) + +- [langerin-negative dermal dendritic cell](http://purl.obolibrary.org/obo/CL_0002459) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010) + + +### langerin-negative, CD103-negative lymph node dendritic cell `http://purl.obolibrary.org/obo/CL_0002508` +#### Removed +- [langerin-negative, CD103-negative lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002508) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-type lectin domain family 4 member K](http://purl.obolibrary.org/obo/PR_000001293)) + +- [langerin-negative, CD103-negative lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002508) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010) + +- [langerin-negative, CD103-negative lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002508) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [langerin-negative, CD103-negative lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002508) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-type lectin domain family 4 member K](http://purl.obolibrary.org/obo/PR_000001293) + +- [langerin-negative, CD103-negative lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002508) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +#### Added +- [langerin-negative, CD103-negative lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002508) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-type lectin domain family 4 member K](http://purl.obolibrary.org/obo/PR_000001293)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) + +- [langerin-negative, CD103-negative lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002508) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010) + +- [langerin-negative, CD103-negative lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002508) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [langerin-negative, CD103-negative lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002508) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [langerin-negative, CD103-negative lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002508) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [C-type lectin domain family 4 member K](http://purl.obolibrary.org/obo/PR_000001293) + + +### langerin-positive lymph node dendritic cell `http://purl.obolibrary.org/obo/CL_0002507` +#### Removed +- [langerin-positive lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002507) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-type lectin domain family 4 member K](http://purl.obolibrary.org/obo/PR_000001293)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) + +- [langerin-positive lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002507) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [langerin-positive lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002507) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +#### Added +- [langerin-positive lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002507) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-type lectin domain family 4 member K](http://purl.obolibrary.org/obo/PR_000001293)) + +- [langerin-positive lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002507) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [langerin-positive lymph node dendritic cell](http://purl.obolibrary.org/obo/CL_0002507) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + + +### large pre-B-II cell `http://purl.obolibrary.org/obo/CL_0000957` +#### Removed +- [large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000957) EquivalentTo [pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000955) and ([participates in](http://purl.obolibrary.org/obo/RO_0000056) some [lymphocyte proliferation](http://purl.obolibrary.org/obo/GO_0046651)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [V(D)J recombination-activating protein 1](http://purl.obolibrary.org/obo/PR_000003457)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [V(D)J recombination-activating protein 2](http://purl.obolibrary.org/obo/PR_000003460)) + +- [large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000957) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [V(D)J recombination-activating protein 2](http://purl.obolibrary.org/obo/PR_000003460) + +- [large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000957) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [V(D)J recombination-activating protein 1](http://purl.obolibrary.org/obo/PR_000003457) + +#### Added +- [large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000957) EquivalentTo [pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000955) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [V(D)J recombination-activating protein 1](http://purl.obolibrary.org/obo/PR_000003457)) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [V(D)J recombination-activating protein 2](http://purl.obolibrary.org/obo/PR_000003460)) and ([participates in](http://purl.obolibrary.org/obo/RO_0000056) some [lymphocyte proliferation](http://purl.obolibrary.org/obo/GO_0046651)) + +- [large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000957) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [V(D)J recombination-activating protein 1](http://purl.obolibrary.org/obo/PR_000003457) + +- [large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000957) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [V(D)J recombination-activating protein 2](http://purl.obolibrary.org/obo/PR_000003460) + + +### larval midgut cell `http://purl.obolibrary.org/obo/CL_0009003` +#### Removed +- [larval midgut cell](http://purl.obolibrary.org/obo/CL_0009003) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### lens of camera-type eye `http://purl.obolibrary.org/obo/UBERON_0000965` +#### Removed +- [lens of camera-type eye](http://purl.obolibrary.org/obo/UBERON_0000965) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "crystalline lens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000723" + +- [lens of camera-type eye](http://purl.obolibrary.org/obo/UBERON_0000965) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "The lens is avascular and nourished by diffusion from the aqueous and vitreous" + +- [lens of camera-type eye](http://purl.obolibrary.org/obo/UBERON_0000965) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Transparent part of camera-type eye that helps to refract light to be focused on the retina." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://orcid.org/0000-0002-6601-2165" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lens_(anatomy)" + +#### Added +- [lens of camera-type eye](http://purl.obolibrary.org/obo/UBERON_0000965) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "crystalline lens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000723" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:36055924" + +- [lens of camera-type eye](http://purl.obolibrary.org/obo/UBERON_0000965) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "The lens is avascular and nourished by diffusion from the aqueous and vitreous humors." + +- [lens of camera-type eye](http://purl.obolibrary.org/obo/UBERON_0000965) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A transparent and refractive lens located posterior to the iris. The lens of camera-type eye refracts light to be focused on the retina." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://orcid.org/0000-0002-6601-2165" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lens_(anatomy)" + + +### lepton `http://purl.obolibrary.org/obo/CHEBI_36338` +#### Removed +- [lepton](http://purl.obolibrary.org/obo/CHEBI_36338) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [lepton](http://purl.obolibrary.org/obo/CHEBI_36338) [label](http://www.w3.org/2000/01/rdf-schema#label) "lepton" + +- [lepton](http://purl.obolibrary.org/obo/CHEBI_36338) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "leptons" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [lepton](http://purl.obolibrary.org/obo/CHEBI_36338) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin)." + +- [lepton](http://purl.obolibrary.org/obo/CHEBI_36338) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36338" + +- [lepton](http://purl.obolibrary.org/obo/CHEBI_36338) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [lepton](http://purl.obolibrary.org/obo/CHEBI_36338) + +- [lepton](http://purl.obolibrary.org/obo/CHEBI_36338) SubClassOf [fundamental particle](http://purl.obolibrary.org/obo/CHEBI_33233) + +- [lepton](http://purl.obolibrary.org/obo/CHEBI_36338) SubClassOf [fermion](http://purl.obolibrary.org/obo/CHEBI_36340) + + + +### ligand-gated calcium channel activity `http://purl.obolibrary.org/obo/GO_0099604` +#### Removed +- [ligand-gated calcium channel activity](http://purl.obolibrary.org/obo/GO_0099604) SubClassOf [ligand-gated monoatomic cation channel activity](http://purl.obolibrary.org/obo/GO_0099094) + +#### Added +- [ligand-gated calcium channel activity](http://purl.obolibrary.org/obo/GO_0099604) SubClassOf [ligand-gated channel activity](http://purl.obolibrary.org/obo/GO_0022834) + + +### ligand-gated monoatomic cation channel activity `http://purl.obolibrary.org/obo/GO_0099094` +#### Removed +- [ligand-gated monoatomic cation channel activity](http://purl.obolibrary.org/obo/GO_0099094) SubClassOf [ligand-gated monoatomic ion channel activity](http://purl.obolibrary.org/obo/GO_0015276) + +#### Added +- [ligand-gated monoatomic cation channel activity](http://purl.obolibrary.org/obo/GO_0099094) SubClassOf [ligand-gated channel activity](http://purl.obolibrary.org/obo/GO_0022834) + + +### linear tetrapyrrole `http://purl.obolibrary.org/obo/CHEBI_25046` +#### Removed +- [linear tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_25046) [label](http://www.w3.org/2000/01/rdf-schema#label) "linear tetrapyrrole" + +- [linear tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_25046) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [linear tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_25046) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25046" + +- [linear tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_25046) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#1_STAR) + +- Class: [linear tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_25046) + +- [linear tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_25046) SubClassOf [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932) + + + +### linear tetrapyrrole anion `http://purl.obolibrary.org/obo/CHEBI_59252` +#### Removed +- [linear tetrapyrrole anion](http://purl.obolibrary.org/obo/CHEBI_59252) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [linear tetrapyrrole anion](http://purl.obolibrary.org/obo/CHEBI_59252) [label](http://www.w3.org/2000/01/rdf-schema#label) "linear tetrapyrrole anion" + +- [linear tetrapyrrole anion](http://purl.obolibrary.org/obo/CHEBI_59252) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "linear tetrapyrrole anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [linear tetrapyrrole anion](http://purl.obolibrary.org/obo/CHEBI_59252) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acyclic tetrapyrrole anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [linear tetrapyrrole anion](http://purl.obolibrary.org/obo/CHEBI_59252) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acyclic tetrapyrrole anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [linear tetrapyrrole anion](http://purl.obolibrary.org/obo/CHEBI_59252) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [linear tetrapyrrole anion](http://purl.obolibrary.org/obo/CHEBI_59252) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An organic anion arising from deprotonation of a acyclic tetrapyrrole compound." + +- [linear tetrapyrrole anion](http://purl.obolibrary.org/obo/CHEBI_59252) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:59252" + +- Class: [linear tetrapyrrole anion](http://purl.obolibrary.org/obo/CHEBI_59252) + +- [linear tetrapyrrole anion](http://purl.obolibrary.org/obo/CHEBI_59252) SubClassOf [organic anion](http://purl.obolibrary.org/obo/CHEBI_25696) + + + +### lipid `http://purl.obolibrary.org/obo/CHEBI_18059` +#### Removed +- [lipid](http://purl.obolibrary.org/obo/CHEBI_18059) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:6486" + +- [lipid](http://purl.obolibrary.org/obo/CHEBI_18059) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Lipid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [lipid](http://purl.obolibrary.org/obo/CHEBI_18059) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01356" + +- [lipid](http://purl.obolibrary.org/obo/CHEBI_18059) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [lipid](http://purl.obolibrary.org/obo/CHEBI_18059) [label](http://www.w3.org/2000/01/rdf-schema#label) "lipid" + +- [lipid](http://purl.obolibrary.org/obo/CHEBI_18059) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lipids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [lipid](http://purl.obolibrary.org/obo/CHEBI_18059) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14517" + +- [lipid](http://purl.obolibrary.org/obo/CHEBI_18059) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:25054" + +- [lipid](http://purl.obolibrary.org/obo/CHEBI_18059) SubClassOf [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) + + + +### lipid catabolic process `http://purl.obolibrary.org/obo/GO_0016042` +#### Removed +- [lipid catabolic process](http://purl.obolibrary.org/obo/GO_0016042) SubClassOf [organic substance catabolic process](http://purl.obolibrary.org/obo/GO_1901575) + +#### Added +- [lipid catabolic process](http://purl.obolibrary.org/obo/GO_0016042) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### lipid import into cell `http://purl.obolibrary.org/obo/GO_0140354` +#### Removed +- [lipid import into cell](http://purl.obolibrary.org/obo/GO_0140354) SubClassOf [import into cell](http://purl.obolibrary.org/obo/GO_0098657) + +#### Added +- [lipid import into cell](http://purl.obolibrary.org/obo/GO_0140354) SubClassOf [has target start location](http://purl.obolibrary.org/obo/RO_0002338) some [extracellular region](http://purl.obolibrary.org/obo/GO_0005576) + +- [lipid import into cell](http://purl.obolibrary.org/obo/GO_0140354) SubClassOf [has target end location](http://purl.obolibrary.org/obo/RO_0002339) some [intracellular anatomical structure](http://purl.obolibrary.org/obo/GO_0005622) + + +### lipid transport `http://purl.obolibrary.org/obo/GO_0006869` +#### Removed +- [lipid transport](http://purl.obolibrary.org/obo/GO_0006869) SubClassOf [organic substance transport](http://purl.obolibrary.org/obo/GO_0071702) + +#### Added +- [lipid transport](http://purl.obolibrary.org/obo/GO_0006869) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### lipoprotein `http://purl.obolibrary.org/obo/CHEBI_6495` +#### Removed +- [lipoprotein](http://purl.obolibrary.org/obo/CHEBI_6495) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [lipoprotein](http://purl.obolibrary.org/obo/CHEBI_6495) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lipoprotein particle" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [lipoprotein](http://purl.obolibrary.org/obo/CHEBI_6495) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lipoproteins" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [lipoprotein](http://purl.obolibrary.org/obo/CHEBI_6495) [label](http://www.w3.org/2000/01/rdf-schema#label) "lipoprotein" + +- [lipoprotein](http://purl.obolibrary.org/obo/CHEBI_6495) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01834" + +- [lipoprotein](http://purl.obolibrary.org/obo/CHEBI_6495) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:6495" + +- [lipoprotein](http://purl.obolibrary.org/obo/CHEBI_6495) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Lipoprotein" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [lipoprotein](http://purl.obolibrary.org/obo/CHEBI_6495) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [lipoprotein](http://purl.obolibrary.org/obo/CHEBI_6495) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids." + +- [lipoprotein](http://purl.obolibrary.org/obo/CHEBI_6495) SubClassOf [conjugated protein](http://purl.obolibrary.org/obo/CHEBI_33837) + +- [lipoprotein](http://purl.obolibrary.org/obo/CHEBI_6495) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) + +- [lipoprotein](http://purl.obolibrary.org/obo/CHEBI_6495) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [apolipoprotein](http://purl.obolibrary.org/obo/CHEBI_39015) + +- [lipoprotein](http://purl.obolibrary.org/obo/CHEBI_6495) SubClassOf [clathrate compound](http://purl.obolibrary.org/obo/CHEBI_39024) + + + +### lipoprotein biosynthetic process `http://purl.obolibrary.org/obo/GO_0042158` +#### Removed +- [lipoprotein biosynthetic process](http://purl.obolibrary.org/obo/GO_0042158) SubClassOf [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) + +- [lipoprotein biosynthetic process](http://purl.obolibrary.org/obo/GO_0042158) SubClassOf [organonitrogen compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901566) + +#### Added +- [lipoprotein biosynthetic process](http://purl.obolibrary.org/obo/GO_0042158) SubClassOf [macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0009059) + + +### lipoprotein catabolic process `http://purl.obolibrary.org/obo/GO_0042159` +#### Removed +- [lipoprotein catabolic process](http://purl.obolibrary.org/obo/GO_0042159) SubClassOf [protein catabolic process](http://purl.obolibrary.org/obo/GO_0030163) + +#### Added +- [lipoprotein catabolic process](http://purl.obolibrary.org/obo/GO_0042159) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### lipoprotein localization `http://purl.obolibrary.org/obo/GO_0044872` +#### Removed +- [lipoprotein localization](http://purl.obolibrary.org/obo/GO_0044872) SubClassOf [protein localization](http://purl.obolibrary.org/obo/GO_0008104) + +#### Added +- [lipoprotein localization](http://purl.obolibrary.org/obo/GO_0044872) SubClassOf [macromolecule localization](http://purl.obolibrary.org/obo/GO_0033036) + + +### lipoprotein localization to membrane `http://purl.obolibrary.org/obo/GO_0044873` +#### Removed +- [lipoprotein localization to membrane](http://purl.obolibrary.org/obo/GO_0044873) SubClassOf [protein localization to membrane](http://purl.obolibrary.org/obo/GO_0072657) + +#### Added +- [lipoprotein localization to membrane](http://purl.obolibrary.org/obo/GO_0044873) SubClassOf [localization within membrane](http://purl.obolibrary.org/obo/GO_0051668) + + +### lipoprotein metabolic process `http://purl.obolibrary.org/obo/GO_0042157` +#### Removed +- [lipoprotein metabolic process](http://purl.obolibrary.org/obo/GO_0042157) SubClassOf [protein metabolic process](http://purl.obolibrary.org/obo/GO_0019538) + +#### Added +- [lipoprotein metabolic process](http://purl.obolibrary.org/obo/GO_0042157) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### lipoprotein transport `http://purl.obolibrary.org/obo/GO_0042953` +#### Removed +- [lipoprotein transport](http://purl.obolibrary.org/obo/GO_0042953) SubClassOf [protein transport](http://purl.obolibrary.org/obo/GO_0015031) + +#### Added +- [lipoprotein transport](http://purl.obolibrary.org/obo/GO_0042953) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### liposaccharide `http://purl.obolibrary.org/obo/CHEBI_35740` +#### Removed +- [liposaccharide](http://purl.obolibrary.org/obo/CHEBI_35740) [label](http://www.w3.org/2000/01/rdf-schema#label) "liposaccharide" + +- [liposaccharide](http://purl.obolibrary.org/obo/CHEBI_35740) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [liposaccharide](http://purl.obolibrary.org/obo/CHEBI_35740) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "liposaccharides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [liposaccharide](http://purl.obolibrary.org/obo/CHEBI_35740) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [liposaccharide](http://purl.obolibrary.org/obo/CHEBI_35740) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35740" + +- Class: [liposaccharide](http://purl.obolibrary.org/obo/CHEBI_35740) + +- [liposaccharide](http://purl.obolibrary.org/obo/CHEBI_35740) SubClassOf [lipid](http://purl.obolibrary.org/obo/CHEBI_18059) + +- [liposaccharide](http://purl.obolibrary.org/obo/CHEBI_35740) SubClassOf [carbohydrate derivative](http://purl.obolibrary.org/obo/CHEBI_63299) + + + +### liposaccharide metabolic process `http://purl.obolibrary.org/obo/GO_1903509` +#### Removed +- [liposaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903509) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "liposaccharide metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [liposaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903509) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-10-01T21:52:52Z" + +- [liposaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903509) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1903509" + +- [liposaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903509) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving liposaccharide." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9452964" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000068" + +- [liposaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903509) [label](http://www.w3.org/2000/01/rdf-schema#label) "liposaccharide metabolic process" + +- [liposaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903509) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "dph" + +- [liposaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903509) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [liposaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903509) + +- [liposaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903509) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [liposaccharide](http://purl.obolibrary.org/obo/CHEBI_35740)) + +- [liposaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903509) SubClassOf [lipid metabolic process](http://purl.obolibrary.org/obo/GO_0006629) + +- [liposaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903509) SubClassOf [carbohydrate derivative metabolic process](http://purl.obolibrary.org/obo/GO_1901135) + +- [liposaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903509) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [liposaccharide](http://purl.obolibrary.org/obo/CHEBI_35740) + + + +### liver CD103-negative dendritic cell `http://purl.obolibrary.org/obo/CL_0002505` +#### Removed +- [liver CD103-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0002505) EquivalentTo [Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0002454) and ([located in](http://purl.obolibrary.org/obo/RO_0001025) some [hepatic sinusoid](http://purl.obolibrary.org/obo/UBERON_0001281)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C](http://purl.obolibrary.org/obo/PR_000001006)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010)) + +- [liver CD103-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0002505) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010) + +#### Added +- [liver CD103-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0002505) EquivalentTo [Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0002454) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010)) and ([located in](http://purl.obolibrary.org/obo/RO_0001025) some [hepatic sinusoid](http://purl.obolibrary.org/obo/UBERON_0001281)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C](http://purl.obolibrary.org/obo/PR_000001006)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) + +- [liver CD103-negative dendritic cell](http://purl.obolibrary.org/obo/CL_0002505) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010) + + +### lobular bronchiole `http://purl.obolibrary.org/obo/UBERON_8600000` +#### Removed +- [lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600000) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](http://orcid.org/0000-0001-6677-8489) + +#### Added +- [lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600000) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + + +### long lived plasma cell `http://purl.obolibrary.org/obo/CL_0000974` +#### Removed +- [long lived plasma cell](http://purl.obolibrary.org/obo/CL_0000974) EquivalentTo [plasma cell](http://purl.obolibrary.org/obo/CL_0000786) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [C-X-C chemokine receptor type 4](http://purl.obolibrary.org/obo/PR_000001208)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [syndecan-1](http://purl.obolibrary.org/obo/PR_000001935)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0019814)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) + +- [long lived plasma cell](http://purl.obolibrary.org/obo/CL_0000974) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + +#### Added +- [long lived plasma cell](http://purl.obolibrary.org/obo/CL_0000974) EquivalentTo [plasma cell](http://purl.obolibrary.org/obo/CL_0000786) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0019814)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [C-X-C chemokine receptor type 4](http://purl.obolibrary.org/obo/PR_000001208)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [syndecan-1](http://purl.obolibrary.org/obo/PR_000001935)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) + +- [long lived plasma cell](http://purl.obolibrary.org/obo/CL_0000974) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408) + + +### long term hematopoietic stem cell `http://purl.obolibrary.org/obo/CL_0002034` +#### Removed +- [long term hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002034) EquivalentTo [Kit and Sca1-positive hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001008) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [Thy-1 membrane glycoprotein](http://purl.obolibrary.org/obo/PR_000001843)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001)) + +- [long term hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002034) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001) + +- [long term hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002034) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + +#### Added +- [long term hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002034) EquivalentTo [Kit and Sca1-positive hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001008) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [Thy-1 membrane glycoprotein](http://purl.obolibrary.org/obo/PR_000001843)) + +- [long term hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002034) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001) + +- [long term hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002034) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + + +### lower urinary tract cell `http://purl.obolibrary.org/obo/CL_1000600` +#### Removed +- [lower urinary tract cell](http://purl.obolibrary.org/obo/CL_1000600) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### lumen of `http://purl.obolibrary.org/obo/RO_0002571` +#### Removed +- [lumen of](http://purl.obolibrary.org/obo/RO_0002571) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [lumen of](http://purl.obolibrary.org/obo/RO_0002571) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### luminal space of `http://purl.obolibrary.org/obo/RO_0002572` +#### Removed +- [luminal space of](http://purl.obolibrary.org/obo/RO_0002572) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [luminal space of](http://purl.obolibrary.org/obo/RO_0002572) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### lung megakaryocyte `http://purl.obolibrary.org/obo/CL_4033018` + +#### Added +- [lung megakaryocyte](http://purl.obolibrary.org/obo/CL_4033018) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lung MKs" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [plural term](http://purl.obolibrary.org/obo/uberon/core#PLURAL) + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [abbreviation](http://purl.obolibrary.org/obo/cl#abbreviation) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:33351116" + +- [lung megakaryocyte](http://purl.obolibrary.org/obo/CL_4033018) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A megakaryocyte that is resident in the lung connective tissue." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:33351116" + +- [lung megakaryocyte](http://purl.obolibrary.org/obo/CL_4033018) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- [lung megakaryocyte](http://purl.obolibrary.org/obo/CL_4033018) [date](http://purl.org/dc/terms/date) "2023-03-16T11:31:23Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [lung megakaryocyte](http://purl.obolibrary.org/obo/CL_4033018) [label](http://www.w3.org/2000/01/rdf-schema#label) "lung megakaryocyte" + +- [lung megakaryocyte](http://purl.obolibrary.org/obo/CL_4033018) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-9185-3994](https://orcid.org/0000-0002-9185-3994) + +- Class: [lung megakaryocyte](http://purl.obolibrary.org/obo/CL_4033018) + +- [lung megakaryocyte](http://purl.obolibrary.org/obo/CL_4033018) SubClassOf [megakaryocyte](http://purl.obolibrary.org/obo/CL_0000556) + + +### lung perichondrial fibroblast `http://purl.obolibrary.org/obo/CL_4033026` + +#### Added +- [lung perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033026) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-9185-3994](https://orcid.org/0000-0002-9185-3994) + +- [lung perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033026) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "PC-fibro" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [abbreviation](http://purl.obolibrary.org/obo/cl#abbreviation) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:36543915" + +- [lung perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033026) [label](http://www.w3.org/2000/01/rdf-schema#label) "lung perichondrial fibroblast" + +- [lung perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033026) [date](http://purl.org/dc/terms/date) "2023-03-16T16:15:39Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [lung perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033026) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- [lung perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033026) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A perichondrial fibroblast that is part of the lung" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:36543915" + +- Class: [lung perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033026) + +- [lung perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033026) EquivalentTo [perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033025) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [lung](http://purl.obolibrary.org/obo/UBERON_0002048)) + +- [lung perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033026) SubClassOf [fibroblast of lung](http://purl.obolibrary.org/obo/CL_0002553) + +- [lung perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033026) SubClassOf [perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033025) + + +### luteinizing hormone secreting cell `http://purl.obolibrary.org/obo/CL_0000438` +#### Removed +- [luteinizing hormone secreting cell](http://purl.obolibrary.org/obo/CL_0000438) SubClassOf [endocrine cell](http://purl.obolibrary.org/obo/CL_0000163) + +#### Added +- [luteinizing hormone secreting cell](http://purl.obolibrary.org/obo/CL_0000438) SubClassOf [secretory cell](http://purl.obolibrary.org/obo/CL_0000151) + + +### lymph node marginal reticular cell `http://purl.obolibrary.org/obo/CL_0009103` +#### Removed +- [lymph node marginal reticular cell](http://purl.obolibrary.org/obo/CL_0009103) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### lymphocyte of B lineage, CD19-positive `http://purl.obolibrary.org/obo/CL_0001200` +#### Removed +- [lymphocyte of B lineage, CD19-positive](http://purl.obolibrary.org/obo/CL_0001200) EquivalentTo [lymphocyte of B lineage](http://purl.obolibrary.org/obo/CL_0000945) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Mammalia](http://purl.obolibrary.org/obo/NCBITaxon_40674)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) + +- [lymphocyte of B lineage, CD19-positive](http://purl.obolibrary.org/obo/CL_0001200) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +#### Added +- [lymphocyte of B lineage, CD19-positive](http://purl.obolibrary.org/obo/CL_0001200) EquivalentTo [lymphocyte of B lineage](http://purl.obolibrary.org/obo/CL_0000945) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Mammalia](http://purl.obolibrary.org/obo/NCBITaxon_40674)) + +- [lymphocyte of B lineage, CD19-positive](http://purl.obolibrary.org/obo/CL_0001200) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + + +### lymphoid MHC-II-negative classical monocyte `http://purl.obolibrary.org/obo/CL_0002474` +#### Removed +- [lymphoid MHC-II-negative classical monocyte](http://purl.obolibrary.org/obo/CL_0002474) EquivalentTo [MHC-II-negative classical monocyte](http://purl.obolibrary.org/obo/CL_0002469) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) + +- [lymphoid MHC-II-negative classical monocyte](http://purl.obolibrary.org/obo/CL_0002474) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013) + +#### Added +- [lymphoid MHC-II-negative classical monocyte](http://purl.obolibrary.org/obo/CL_0002474) EquivalentTo [MHC-II-negative classical monocyte](http://purl.obolibrary.org/obo/CL_0002469) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) + +- [lymphoid MHC-II-negative classical monocyte](http://purl.obolibrary.org/obo/CL_0002474) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013) + + +### macromolecule `http://purl.obolibrary.org/obo/CHEBI_33839` +#### Removed +- [macromolecule](http://purl.obolibrary.org/obo/CHEBI_33839) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polymer" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [macromolecule](http://purl.obolibrary.org/obo/CHEBI_33839) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polymer molecule" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [macromolecule](http://purl.obolibrary.org/obo/CHEBI_33839) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "macromolecule" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [macromolecule](http://purl.obolibrary.org/obo/CHEBI_33839) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [macromolecule](http://purl.obolibrary.org/obo/CHEBI_33839) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33839" + +- [macromolecule](http://purl.obolibrary.org/obo/CHEBI_33839) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." + +- [macromolecule](http://purl.obolibrary.org/obo/CHEBI_33839) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polymers" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [macromolecule](http://purl.obolibrary.org/obo/CHEBI_33839) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [macromolecule](http://purl.obolibrary.org/obo/CHEBI_33839) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "macromolecules" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [macromolecule](http://purl.obolibrary.org/obo/CHEBI_33839) [label](http://www.w3.org/2000/01/rdf-schema#label) "macromolecule" + +- [macromolecule](http://purl.obolibrary.org/obo/CHEBI_33839) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Macromolecule" + +- Class: [macromolecule](http://purl.obolibrary.org/obo/CHEBI_33839) + +- [macromolecule](http://purl.obolibrary.org/obo/CHEBI_33839) SubClassOf [polyatomic entity](http://purl.obolibrary.org/obo/CHEBI_36357) + + + +### macromolecule biosynthetic process `http://purl.obolibrary.org/obo/GO_0009059` + +#### Added +- [macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0009059) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "http://amigo.geneontology.org/amigo/term/GO:0070589"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### macromolecule catabolic process `http://purl.obolibrary.org/obo/GO_0009057` +#### Removed +- [macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0009057) SubClassOf [organic substance catabolic process](http://purl.obolibrary.org/obo/GO_1901575) + +#### Added +- [macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0009057) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cellular macromolecule catabolic process" + +- [macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0009057) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cellular macromolecule catabolism" + +- [macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0009057) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cellular macromolecule degradation" + +- [macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0009057) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### macromolecule metabolic process `http://purl.obolibrary.org/obo/GO_0043170` +#### Removed +- [macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0043170) SubClassOf [organic substance metabolic process](http://purl.obolibrary.org/obo/GO_0071704) + +#### Added +- [macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0043170) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0034960" + +- [macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0043170) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### macronutrient `http://purl.obolibrary.org/obo/CHEBI_33937` +#### Removed +- [macronutrient](http://purl.obolibrary.org/obo/CHEBI_33937) [label](http://www.w3.org/2000/01/rdf-schema#label) "macronutrient" + +- [macronutrient](http://purl.obolibrary.org/obo/CHEBI_33937) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [macronutrient](http://purl.obolibrary.org/obo/CHEBI_33937) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33937" + +- [macronutrient](http://purl.obolibrary.org/obo/CHEBI_33937) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [macronutrient](http://purl.obolibrary.org/obo/CHEBI_33937) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals." + +- [macronutrient](http://purl.obolibrary.org/obo/CHEBI_33937) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "macronutrients" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [macronutrient](http://purl.obolibrary.org/obo/CHEBI_33937) + +- [macronutrient](http://purl.obolibrary.org/obo/CHEBI_33937) SubClassOf [nutrient](http://purl.obolibrary.org/obo/CHEBI_33284) + + + +### main group element atom `http://purl.obolibrary.org/obo/CHEBI_33318` +#### Removed +- [main group element atom](http://purl.obolibrary.org/obo/CHEBI_33318) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table." + +- [main group element atom](http://purl.obolibrary.org/obo/CHEBI_33318) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [main group element atom](http://purl.obolibrary.org/obo/CHEBI_33318) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [main group element atom](http://purl.obolibrary.org/obo/CHEBI_33318) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Hauptgruppenelemente" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [main group element atom](http://purl.obolibrary.org/obo/CHEBI_33318) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "main group elements" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [main group element atom](http://purl.obolibrary.org/obo/CHEBI_33318) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Hauptgruppenelement" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [main group element atom](http://purl.obolibrary.org/obo/CHEBI_33318) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "main group element" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [main group element atom](http://purl.obolibrary.org/obo/CHEBI_33318) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33318" + +- [main group element atom](http://purl.obolibrary.org/obo/CHEBI_33318) [label](http://www.w3.org/2000/01/rdf-schema#label) "main group element atom" + +- Class: [main group element atom](http://purl.obolibrary.org/obo/CHEBI_33318) + +- [main group element atom](http://purl.obolibrary.org/obo/CHEBI_33318) SubClassOf [atom](http://purl.obolibrary.org/obo/CHEBI_33250) + + + +### main group molecular entity `http://purl.obolibrary.org/obo/CHEBI_33579` +#### Removed +- [main group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33579) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "main group compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [main group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33579) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33579" + +- [main group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33579) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [main group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33579) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [main group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33579) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "main group molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [main group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33579) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "main group compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [main group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33579) [label](http://www.w3.org/2000/01/rdf-schema#label) "main group molecular entity" + +- [main group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33579) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [main group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33579) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "main group molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- Class: [main group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33579) + +- [main group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33579) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [main group element atom](http://purl.obolibrary.org/obo/CHEBI_33318) + +- [main group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33579) SubClassOf [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) + + + +### malpighian tubule tip cell `http://purl.obolibrary.org/obo/CL_1000182` +#### Removed +- [malpighian tubule tip cell](http://purl.obolibrary.org/obo/CL_1000182) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### mammalian metabolite `http://purl.obolibrary.org/obo/CHEBI_75768` +#### Removed +- [mammalian metabolite](http://purl.obolibrary.org/obo/CHEBI_75768) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:77464" + +- [mammalian metabolite](http://purl.obolibrary.org/obo/CHEBI_75768) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mammalian metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [mammalian metabolite](http://purl.obolibrary.org/obo/CHEBI_75768) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [mammalian metabolite](http://purl.obolibrary.org/obo/CHEBI_75768) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:77744" + +- [mammalian metabolite](http://purl.obolibrary.org/obo/CHEBI_75768) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:75768" + +- [mammalian metabolite](http://purl.obolibrary.org/obo/CHEBI_75768) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [mammalian metabolite](http://purl.obolibrary.org/obo/CHEBI_75768) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any animal metabolite produced during a metabolic reaction in mammals." + +- [mammalian metabolite](http://purl.obolibrary.org/obo/CHEBI_75768) [label](http://www.w3.org/2000/01/rdf-schema#label) "mammalian metabolite" + +- Class: [mammalian metabolite](http://purl.obolibrary.org/obo/CHEBI_75768) + +- [mammalian metabolite](http://purl.obolibrary.org/obo/CHEBI_75768) SubClassOf [animal metabolite](http://purl.obolibrary.org/obo/CHEBI_75767) + + + +### mammary alveolar cell `http://purl.obolibrary.org/obo/CL_0002325` +#### Removed +- [mammary alveolar cell](http://purl.obolibrary.org/obo/CL_0002325) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000476" + +- [mammary alveolar cell](http://purl.obolibrary.org/obo/CL_0002325) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0002230" + + + +### marginal zone B cell of spleen `http://purl.obolibrary.org/obo/CL_0000845` +#### Removed +- [marginal zone B cell of spleen](http://purl.obolibrary.org/obo/CL_0000845) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [marginal zone of spleen](http://purl.obolibrary.org/obo/UBERON_0001251)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [defense response to bacterium](http://purl.obolibrary.org/obo/GO_0042742)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) + +- [marginal zone B cell of spleen](http://purl.obolibrary.org/obo/CL_0000845) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880) + +- [marginal zone B cell of spleen](http://purl.obolibrary.org/obo/CL_0000845) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037) + +#### Added +- [marginal zone B cell of spleen](http://purl.obolibrary.org/obo/CL_0000845) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [marginal zone of spleen](http://purl.obolibrary.org/obo/UBERON_0001251)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement receptor type 2](http://purl.obolibrary.org/obo/PR_000001338)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [defense response to bacterium](http://purl.obolibrary.org/obo/GO_0042742)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) + +- [marginal zone B cell of spleen](http://purl.obolibrary.org/obo/CL_0000845) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin epsilon Fc receptor](http://purl.obolibrary.org/obo/PR_000001880) + +- [marginal zone B cell of spleen](http://purl.obolibrary.org/obo/CL_0000845) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037) + + +### mass `http://purl.obolibrary.org/obo/chebi/mass` +#### Removed +- AnnotationProperty: [mass](http://purl.obolibrary.org/obo/chebi/mass) + + + +### mast cell `http://purl.obolibrary.org/obo/CL_0000097` +#### Removed +- [mast cell](http://purl.obolibrary.org/obo/CL_0000097) EquivalentTo [myeloid leukocyte](http://purl.obolibrary.org/obo/CL_0000766) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [secretory granule](http://purl.obolibrary.org/obo/GO_0030141)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001255)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [cell surface glycoprotein CD200 receptor 3](http://purl.obolibrary.org/obo/PR_000006169)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [histamine production involved in inflammatory response](http://purl.obolibrary.org/obo/GO_0002349)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [prostaglandin production involved in inflammatory response](http://purl.obolibrary.org/obo/GO_0002539)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of peripheral tolerance induction](http://purl.obolibrary.org/obo/GO_0002660)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of leukocyte chemotaxis](http://purl.obolibrary.org/obo/GO_0002690)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of type 2 immune response](http://purl.obolibrary.org/obo/GO_0002830)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [heparin biosynthetic process](http://purl.obolibrary.org/obo/GO_0030210)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) + +- [mast cell](http://purl.obolibrary.org/obo/CL_0000097) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865) + +#### Added +- [mast cell](http://purl.obolibrary.org/obo/CL_0000097) EquivalentTo [myeloid leukocyte](http://purl.obolibrary.org/obo/CL_0000766) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [secretory granule](http://purl.obolibrary.org/obo/GO_0030141)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 3](http://purl.obolibrary.org/obo/PR_000001255)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [cell surface glycoprotein CD200 receptor 3](http://purl.obolibrary.org/obo/PR_000006169)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [histamine production involved in inflammatory response](http://purl.obolibrary.org/obo/GO_0002349)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [prostaglandin production involved in inflammatory response](http://purl.obolibrary.org/obo/GO_0002539)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of peripheral tolerance induction](http://purl.obolibrary.org/obo/GO_0002660)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of leukocyte chemotaxis](http://purl.obolibrary.org/obo/GO_0002690)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of type 2 immune response](http://purl.obolibrary.org/obo/GO_0002830)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [heparin biosynthetic process](http://purl.obolibrary.org/obo/GO_0030210)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431)) + +- [mast cell](http://purl.obolibrary.org/obo/CL_0000097) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865) + + +### mast cell progenitor `http://purl.obolibrary.org/obo/CL_0000831` +#### Removed +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) EquivalentTo [myeloid lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0000839) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [erythroid transcription factor](http://purl.obolibrary.org/obo/PR_000007857)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [endothelial transcription factor GATA-2](http://purl.obolibrary.org/obo/PR_000007858)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD9 molecule](http://purl.obolibrary.org/obo/PR_000005178)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [transmembrane emp24 domain-containing protein 1](http://purl.obolibrary.org/obo/PR_000016401)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [mast cell differentiation](http://purl.obolibrary.org/obo/GO_0060374)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [integrin beta-7](http://purl.obolibrary.org/obo/PR_000009143)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +#### Added +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) EquivalentTo [myeloid lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0000839) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [erythroid transcription factor](http://purl.obolibrary.org/obo/PR_000007857)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [endothelial transcription factor GATA-2](http://purl.obolibrary.org/obo/PR_000007858)) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD9 molecule](http://purl.obolibrary.org/obo/PR_000005178)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [transmembrane emp24 domain-containing protein 1](http://purl.obolibrary.org/obo/PR_000016401)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [mast cell differentiation](http://purl.obolibrary.org/obo/GO_0060374)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [integrin beta-7](http://purl.obolibrary.org/obo/PR_000009143)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [high affinity immunoglobulin epsilon receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000007431)) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6C2](http://purl.obolibrary.org/obo/PR_000002980) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [mast cell progenitor](http://purl.obolibrary.org/obo/CL_0000831) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + + +### mature basophil `http://purl.obolibrary.org/obo/CL_0000043` +#### Removed +- [mature basophil](http://purl.obolibrary.org/obo/CL_0000043) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000739" + + + +### mature neutrophil `http://purl.obolibrary.org/obo/CL_0000096` +#### Removed +- [mature neutrophil](http://purl.obolibrary.org/obo/CL_0000096) EquivalentTo [neutrophil](http://purl.obolibrary.org/obo/CL_0000775) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [neutrophillic cytoplasm](http://purl.obolibrary.org/obo/CL_0017500)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [tertiary granule](http://purl.obolibrary.org/obo/GO_0070820)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some +([nucleus](http://purl.obolibrary.org/obo/GO_0005634) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [lobed](http://purl.obolibrary.org/obo/PATO_0001979)))) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-X-C chemokine receptor type 1](http://purl.obolibrary.org/obo/PR_000001256)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-X-C chemokine receptor type 2](http://purl.obolibrary.org/obo/PR_000001257)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-(1,3)-fucosyltransferase 4](http://purl.obolibrary.org/obo/PR_000001456)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [transcription factor PU.1](http://purl.obolibrary.org/obo/PR_000001944)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [protein c-Fos](http://purl.obolibrary.org/obo/PR_000007597)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [respiratory burst involved in inflammatory response](http://purl.obolibrary.org/obo/GO_0002536)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of leukocyte chemotaxis](http://purl.obolibrary.org/obo/GO_0002690)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [phagocytosis](http://purl.obolibrary.org/obo/GO_0006909)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-8 production](http://purl.obolibrary.org/obo/GO_0032637)) and ([lacks_part](http://purl.obolibrary.org/obo/pr#lacks_part) some [lactotransferrin](http://purl.obolibrary.org/obo/PR_000009978)) and ([lacks_part](http://purl.obolibrary.org/obo/pr#lacks_part) some [myeloperoxidase](http://purl.obolibrary.org/obo/PR_000010543)) and ([lacks_part](http://purl.obolibrary.org/obo/pr#lacks_part) some [myb proto-oncogene protein](http://purl.obolibrary.org/obo/PR_000010799)) + +- [mature neutrophil](http://purl.obolibrary.org/obo/CL_0000096) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/pr#lacks_part) some [myeloperoxidase](http://purl.obolibrary.org/obo/PR_000010543) + +- [mature neutrophil](http://purl.obolibrary.org/obo/CL_0000096) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/pr#lacks_part) some [lactotransferrin](http://purl.obolibrary.org/obo/PR_000009978) + +- [mature neutrophil](http://purl.obolibrary.org/obo/CL_0000096) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/pr#lacks_part) some [myb proto-oncogene protein](http://purl.obolibrary.org/obo/PR_000010799) + +#### Added +- [mature neutrophil](http://purl.obolibrary.org/obo/CL_0000096) EquivalentTo [neutrophil](http://purl.obolibrary.org/obo/CL_0000775) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [neutrophillic cytoplasm](http://purl.obolibrary.org/obo/CL_0017500)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [tertiary granule](http://purl.obolibrary.org/obo/GO_0070820)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some +([nucleus](http://purl.obolibrary.org/obo/GO_0005634) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [lobed](http://purl.obolibrary.org/obo/PATO_0001979)))) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [lactotransferrin](http://purl.obolibrary.org/obo/PR_000009978)) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [myeloperoxidase](http://purl.obolibrary.org/obo/PR_000010543)) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [myb proto-oncogene protein](http://purl.obolibrary.org/obo/PR_000010799)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-X-C chemokine receptor type 1](http://purl.obolibrary.org/obo/PR_000001256)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-X-C chemokine receptor type 2](http://purl.obolibrary.org/obo/PR_000001257)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-(1,3)-fucosyltransferase 4](http://purl.obolibrary.org/obo/PR_000001456)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [leukosialin](http://purl.obolibrary.org/obo/PR_000001879)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [transcription factor PU.1](http://purl.obolibrary.org/obo/PR_000001944)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [protein c-Fos](http://purl.obolibrary.org/obo/PR_000007597)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [respiratory burst involved in inflammatory response](http://purl.obolibrary.org/obo/GO_0002536)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [positive regulation of leukocyte chemotaxis](http://purl.obolibrary.org/obo/GO_0002690)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [phagocytosis](http://purl.obolibrary.org/obo/GO_0006909)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-8 production](http://purl.obolibrary.org/obo/GO_0032637)) + +- [mature neutrophil](http://purl.obolibrary.org/obo/CL_0000096) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [lactotransferrin](http://purl.obolibrary.org/obo/PR_000009978) + +- [mature neutrophil](http://purl.obolibrary.org/obo/CL_0000096) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [myb proto-oncogene protein](http://purl.obolibrary.org/obo/PR_000010799) + +- [mature neutrophil](http://purl.obolibrary.org/obo/CL_0000096) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [myeloperoxidase](http://purl.obolibrary.org/obo/PR_000010543) + + +### megakaryocyte `http://purl.obolibrary.org/obo/CL_0000556` +#### Removed +- [megakaryocyte](http://purl.obolibrary.org/obo/CL_0000556) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://en.wikipedia.org/wiki/Megakaryocyte" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0721601464" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D008533" + +- [megakaryocyte](http://purl.obolibrary.org/obo/CL_0000556) EquivalentTo [myeloid cell](http://purl.obolibrary.org/obo/CL_0000763) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [bone marrow](http://purl.obolibrary.org/obo/UBERON_0002371)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [euploid](http://purl.obolibrary.org/obo/PATO_0001393)) + +- [megakaryocyte](http://purl.obolibrary.org/obo/CL_0000556) SubClassOf [bone marrow hematopoietic cell](http://purl.obolibrary.org/obo/CL_1001610) + +#### Added +- [megakaryocyte](http://purl.obolibrary.org/obo/CL_0000556) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:31043076" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://en.wikipedia.org/wiki/Megakaryocyte" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0721601464" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D008533" + + +### megakaryocyte development `http://purl.obolibrary.org/obo/GO_0035855` +#### Removed +- [megakaryocyte development](http://purl.obolibrary.org/obo/GO_0035855) SubClassOf [bone cell development](http://purl.obolibrary.org/obo/GO_0098751) + + + +### megakaryocyte progenitor cell `http://purl.obolibrary.org/obo/CL_0000553` +#### Removed +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) EquivalentTo [myeloid lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0000839) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [endomitotic cell cycle](http://purl.obolibrary.org/obo/GO_0007113)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [megakaryocyte differentiation](http://purl.obolibrary.org/obo/GO_0030219)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +#### Added +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) EquivalentTo [myeloid lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0000839) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [endomitotic cell cycle](http://purl.obolibrary.org/obo/GO_0007113)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [megakaryocyte differentiation](http://purl.obolibrary.org/obo/GO_0030219)) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + + +### meiotic cell cycle `http://purl.obolibrary.org/obo/GO_0051321` + +#### Added +- [meiotic cell cycle](http://purl.obolibrary.org/obo/GO_0051321) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24599"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [meiotic cell cycle](http://purl.obolibrary.org/obo/GO_0051321) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [sexual reproduction](http://purl.obolibrary.org/obo/GO_0019953) + + +### melanocyte `http://purl.obolibrary.org/obo/CL_0000148` +#### Removed +- [melanocyte](http://purl.obolibrary.org/obo/CL_0000148) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000572" + + + +### melatonin `http://purl.obolibrary.org/obo/CHEBI_16796` +#### Removed +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16678784" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:73-31-4" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:6730" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "melatonine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01598" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:205542" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:205542" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Melatonin" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:ML1" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18212404" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C=1C=C(C=C2C(=CNC12)CCNC(=O)C)OC" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "melatonin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "N-[2-(5-methoxyindol-3-yl)ethyl]acetamide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "N-Acetyl-5-methoxytryptamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14577" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0001389" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [mass](http://purl.obolibrary.org/obo/chebi/mass) "232.283" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:1672" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen atom is replaced by a 2-(5-methoxy-1H-indol-3-yl)ethyl group. It is a hormone secreted by the pineal gland in humans." + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [label](http://www.w3.org/2000/01/rdf-schema#label) "melatonin" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "DRLFMBDRBRZALE-UHFFFAOYSA-N" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LINCS:LSM-4779" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Melatonin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:N-ACETYL-5-METHOXY-TRYPTAMINE" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C13H16N2O2" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:25180" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D08170" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB01065" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18485664" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:16796" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:8290600" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:73-31-4" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "232.12118" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "5-methoxy-N-acetyltryptamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:73-31-4" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [anticonvulsant](http://purl.obolibrary.org/obo/CHEBI_35623) + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [immunological adjuvant](http://purl.obolibrary.org/obo/CHEBI_50847) + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [hormone](http://purl.obolibrary.org/obo/CHEBI_24621) + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) SubClassOf [tryptamines](http://purl.obolibrary.org/obo/CHEBI_27162) + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [geroprotector](http://purl.obolibrary.org/obo/CHEBI_176497) + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [radical scavenger](http://purl.obolibrary.org/obo/CHEBI_48578) + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) SubClassOf [acetamides](http://purl.obolibrary.org/obo/CHEBI_22160) + +- [melatonin](http://purl.obolibrary.org/obo/CHEBI_16796) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) + + + +### melatonin binding `http://purl.obolibrary.org/obo/GO_1904408` +#### Removed +- [melatonin binding](http://purl.obolibrary.org/obo/GO_1904408) SubClassOf [organic cyclic compound binding](http://purl.obolibrary.org/obo/GO_0097159) + +- [melatonin binding](http://purl.obolibrary.org/obo/GO_1904408) SubClassOf [amide binding](http://purl.obolibrary.org/obo/GO_0033218) + +- [melatonin binding](http://purl.obolibrary.org/obo/GO_1904408) SubClassOf [heterocyclic compound binding](http://purl.obolibrary.org/obo/GO_1901363) + +#### Added +- [melatonin binding](http://purl.obolibrary.org/obo/GO_1904408) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### melatonin catabolic process `http://purl.obolibrary.org/obo/GO_0042442` +#### Removed +- [melatonin catabolic process](http://purl.obolibrary.org/obo/GO_0042442) SubClassOf [indole-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0042436) + + + +### membrane lipid biosynthetic process `http://purl.obolibrary.org/obo/GO_0046467` +#### Removed +- [membrane lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046467) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrane lipid anabolism" + +- [membrane lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046467) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrane lipid biosynthesis" + +- [membrane lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046467) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrane lipid synthesis" + +- [membrane lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046467) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrane lipid formation" + +- [membrane lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046467) [label](http://www.w3.org/2000/01/rdf-schema#label) "membrane lipid biosynthetic process" + +- [membrane lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046467) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046467" + +- [membrane lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046467) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [membrane lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046467) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- Class: [membrane lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046467) + +- [membrane lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046467) SubClassOf [lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008610) + +- [membrane lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046467) SubClassOf [cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0044249) + +- [membrane lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046467) SubClassOf [membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_0006643) + + + +### membrane lipid catabolic process `http://purl.obolibrary.org/obo/GO_0046466` +#### Removed +- [membrane lipid catabolic process](http://purl.obolibrary.org/obo/GO_0046466) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "membrane lipid peroxidation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [membrane lipid catabolic process](http://purl.obolibrary.org/obo/GO_0046466) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrane lipid catabolism" + +- [membrane lipid catabolic process](http://purl.obolibrary.org/obo/GO_0046466) [label](http://www.w3.org/2000/01/rdf-schema#label) "membrane lipid catabolic process" + +- [membrane lipid catabolic process](http://purl.obolibrary.org/obo/GO_0046466) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [membrane lipid catabolic process](http://purl.obolibrary.org/obo/GO_0046466) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [membrane lipid catabolic process](http://purl.obolibrary.org/obo/GO_0046466) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrane lipid breakdown" + +- [membrane lipid catabolic process](http://purl.obolibrary.org/obo/GO_0046466) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrane lipid degradation" + +- [membrane lipid catabolic process](http://purl.obolibrary.org/obo/GO_0046466) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046466" + +- Class: [membrane lipid catabolic process](http://purl.obolibrary.org/obo/GO_0046466) + +- [membrane lipid catabolic process](http://purl.obolibrary.org/obo/GO_0046466) SubClassOf [membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_0006643) + +- [membrane lipid catabolic process](http://purl.obolibrary.org/obo/GO_0046466) SubClassOf [cellular lipid catabolic process](http://purl.obolibrary.org/obo/GO_0044242) + + + +### membrane lipid metabolic process `http://purl.obolibrary.org/obo/GO_0006643` +#### Removed +- [membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_0006643) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrane lipid metabolism" + +- [membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_0006643) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006643" + +- [membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_0006643) [label](http://www.w3.org/2000/01/rdf-schema#label) "membrane lipid metabolic process" + +- [membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_0006643) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_0006643) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- Class: [membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_0006643) + +- [membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_0006643) SubClassOf [cellular lipid metabolic process](http://purl.obolibrary.org/obo/GO_0044255) + + + +### memory B cell `http://purl.obolibrary.org/obo/CL_0000787` +#### Removed +- [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [B cell affinity maturation](http://purl.obolibrary.org/obo/GO_0002344)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [syndecan-1](http://purl.obolibrary.org/obo/PR_000001935)) + +- [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [syndecan-1](http://purl.obolibrary.org/obo/PR_000001935) + +#### Added +- [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [syndecan-1](http://purl.obolibrary.org/obo/PR_000001935)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [B cell affinity maturation](http://purl.obolibrary.org/obo/GO_0002344)) + +- [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [syndecan-1](http://purl.obolibrary.org/obo/PR_000001935) + + +### mereotopologically related to `http://purl.obolibrary.org/obo/RO_0002323` +#### Removed +- [mereotopologically related to](http://purl.obolibrary.org/obo/RO_0002323) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [mereotopologically related to](http://purl.obolibrary.org/obo/RO_0002323) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### mesenchymal stem cell `http://purl.obolibrary.org/obo/CL_0000134` +#### Removed +- [mesenchymal stem cell](http://purl.obolibrary.org/obo/CL_0000134) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0002452" + + + +### mesenchyme of ovary `http://purl.obolibrary.org/obo/UBERON_0003315` + +#### Added +- [mesenchyme of ovary](http://purl.obolibrary.org/obo/UBERON_0003315) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + +- [mesenchyme of ovary](http://purl.obolibrary.org/obo/UBERON_0003315) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + + +### mesenteric lymphatic vessel `http://purl.obolibrary.org/obo/UBERON_8480006` +#### Removed +- [mesenteric lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_8480006) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](http://orcid.org/0000-0002-0819-0473) + +#### Added +- [mesenteric lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_8480006) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](https://orcid.org/0000-0002-0819-0473) + + +### mesodermal cell `http://purl.obolibrary.org/obo/CL_0000222` +#### Removed +- [mesodermal cell](http://purl.obolibrary.org/obo/CL_0000222) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### metabolite `http://purl.obolibrary.org/obo/CHEBI_25212` +#### Removed +- [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25212" + +- [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "metabolite" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:26619" + +- [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "secondary metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) [label](http://www.w3.org/2000/01/rdf-schema#label) "metabolite" + +- [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites." + +- [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "primary metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:35220" + +- Class: [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) + +- [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) SubClassOf [biochemical role](http://purl.obolibrary.org/obo/CHEBI_52206) + + + +### metal atom `http://purl.obolibrary.org/obo/CHEBI_33521` +#### Removed +- [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:6788" + +- [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metals" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "elemental metals" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Metal" + +- [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metal elements" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:25217" + +- [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00050" + +- [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21784043" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) [label](http://www.w3.org/2000/01/rdf-schema#label) "metal atom" + +- [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "elemental metal" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metal element" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity." + +- [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33521" + +- Class: [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) + +- [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) SubClassOf [atom](http://purl.obolibrary.org/obo/CHEBI_33250) + + + +### metal cation `http://purl.obolibrary.org/obo/CHEBI_25213` +#### Removed +- [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metal cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25213" + +- [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a metal cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) [label](http://www.w3.org/2000/01/rdf-schema#label) "metal cation" + +- Class: [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) + +- [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) SubClassOf [monoatomic cation](http://purl.obolibrary.org/obo/CHEBI_23906) + +- [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) SubClassOf [inorganic cation](http://purl.obolibrary.org/obo/CHEBI_36915) + + + +### metal ion binding `http://purl.obolibrary.org/obo/GO_0046872` +#### Removed +- [metal ion binding](http://purl.obolibrary.org/obo/GO_0046872) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_agr](http://purl.obolibrary.org/obo/go#goslim_agr) + +- [metal ion binding](http://purl.obolibrary.org/obo/GO_0046872) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to a metal ion." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [metal ion binding](http://purl.obolibrary.org/obo/GO_0046872) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046872" + +- [metal ion binding](http://purl.obolibrary.org/obo/GO_0046872) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_flybase_ribbon](http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon) + +- [metal ion binding](http://purl.obolibrary.org/obo/GO_0046872) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_metagenomics](http://purl.obolibrary.org/obo/go#goslim_metagenomics) + +- [metal ion binding](http://purl.obolibrary.org/obo/GO_0046872) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_drosophila](http://purl.obolibrary.org/obo/go#goslim_drosophila) + +- [metal ion binding](http://purl.obolibrary.org/obo/GO_0046872) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "heavy metal binding" + +- [metal ion binding](http://purl.obolibrary.org/obo/GO_0046872) [label](http://www.w3.org/2000/01/rdf-schema#label) "metal ion binding" + +- [metal ion binding](http://purl.obolibrary.org/obo/GO_0046872) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "metal binding" + +- [metal ion binding](http://purl.obolibrary.org/obo/GO_0046872) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- Class: [metal ion binding](http://purl.obolibrary.org/obo/GO_0046872) + +- [metal ion binding](http://purl.obolibrary.org/obo/GO_0046872) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213)) + +- [metal ion binding](http://purl.obolibrary.org/obo/GO_0046872) SubClassOf [cation binding](http://purl.obolibrary.org/obo/GO_0043169) + +- [metal ion binding](http://purl.obolibrary.org/obo/GO_0046872) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) + + + +### metal ion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0046873` +#### Removed +- [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "heavy metal-exporting ATPase activity" + +- [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "heavy metal ion:hydrogen symporter activity" + +- [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of metal ions from one side of a membrane to the other." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "high affinity metal ion uptake transporter activity" + +- [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "heavy metal ion porter activity" + +- [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "heavy metal ion transporter activity" + +- [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046873" + +- [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "low affinity metal ion uptake transporter activity" + +- [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) [label](http://www.w3.org/2000/01/rdf-schema#label) "metal ion transmembrane transporter activity" + +- [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- Class: [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) + +- [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213)) + +- [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) SubClassOf [monoatomic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008324) + +- [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) + +- [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) SubClassOf [inorganic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022890) + +- [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) + + + +### metal ion transport `http://purl.obolibrary.org/obo/GO_0030001` +#### Removed +- [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0070838" + +- [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) [label](http://www.w3.org/2000/01/rdf-schema#label) "metal ion transport" + +- [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "heavy metal ion transport" + +- [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "metal ion export" + +- [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2009-07-31T01:07:46Z" + +- [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/23033"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "divalent metal ion transport" + +- [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "divalent metal ion export" + +- [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0030001" + +- [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0070839" + +- [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) + +- [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213)) + +- [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) SubClassOf [monoatomic cation transport](http://purl.obolibrary.org/obo/GO_0006812) + +- [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) + + + +### micronutrient `http://purl.obolibrary.org/obo/CHEBI_27027` +#### Removed +- [micronutrient](http://purl.obolibrary.org/obo/CHEBI_27027) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:27027" + +- [micronutrient](http://purl.obolibrary.org/obo/CHEBI_27027) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "micronutrients" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [micronutrient](http://purl.obolibrary.org/obo/CHEBI_27027) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions." + +- [micronutrient](http://purl.obolibrary.org/obo/CHEBI_27027) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Micronutrient" + +- [micronutrient](http://purl.obolibrary.org/obo/CHEBI_27027) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trace elements" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [micronutrient](http://purl.obolibrary.org/obo/CHEBI_27027) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [micronutrient](http://purl.obolibrary.org/obo/CHEBI_27027) [label](http://www.w3.org/2000/01/rdf-schema#label) "micronutrient" + +- [micronutrient](http://purl.obolibrary.org/obo/CHEBI_27027) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [micronutrient](http://purl.obolibrary.org/obo/CHEBI_27027) + +- [micronutrient](http://purl.obolibrary.org/obo/CHEBI_27027) SubClassOf [nutrient](http://purl.obolibrary.org/obo/CHEBI_33284) + + + +### micropylar cell `http://purl.obolibrary.org/obo/CL_0007022` +#### Removed +- [micropylar cell](http://purl.obolibrary.org/obo/CL_0007022) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### midbrain-derived inhibitory neuron `http://purl.obolibrary.org/obo/CL_4023079` +#### Removed +- [midbrain-derived inhibitory neuron](http://purl.obolibrary.org/obo/CL_4023079) SubClassOf [anatomical entity](http://purl.obolibrary.org/obo/CARO_0000000) + +#### Added +- [midbrain-derived inhibitory neuron](http://purl.obolibrary.org/obo/CL_4023079) SubClassOf [ectoderm-derived structure](http://purl.obolibrary.org/obo/UBERON_0004121) + + +### mineral `http://purl.obolibrary.org/obo/CHEBI_46662` +#### Removed +- [mineral](http://purl.obolibrary.org/obo/CHEBI_46662) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "minerales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [mineral](http://purl.obolibrary.org/obo/CHEBI_46662) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [mineral](http://purl.obolibrary.org/obo/CHEBI_46662) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "In general, a mineral is a chemical substance that is normally crystalline formed and has been formed as a result of geological processes. The term also includes metamict substances (naturally occurring, formerly crystalline substances whose crystallinity has been destroyed by ionising radiation) and can include naturally occurring amorphous substances that have never been crystalline ('mineraloids') such as georgite and calciouranoite as well as substances formed by the action of geological processes on bigenic compounds ('biogenic minerals')." + +- [mineral](http://purl.obolibrary.org/obo/CHEBI_46662) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "mineral" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [mineral](http://purl.obolibrary.org/obo/CHEBI_46662) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mineraux" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [mineral](http://purl.obolibrary.org/obo/CHEBI_46662) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:46662" + +- [mineral](http://purl.obolibrary.org/obo/CHEBI_46662) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [mineral](http://purl.obolibrary.org/obo/CHEBI_46662) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Minerale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [mineral](http://purl.obolibrary.org/obo/CHEBI_46662) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mineral" + +- [mineral](http://purl.obolibrary.org/obo/CHEBI_46662) [label](http://www.w3.org/2000/01/rdf-schema#label) "mineral" + +- [mineral](http://purl.obolibrary.org/obo/CHEBI_46662) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "minerals" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [mineral](http://purl.obolibrary.org/obo/CHEBI_46662) + +- [mineral](http://purl.obolibrary.org/obo/CHEBI_46662) SubClassOf [chemical substance](http://purl.obolibrary.org/obo/CHEBI_59999) + + + +### mineralocorticoid `http://purl.obolibrary.org/obo/CHEBI_25354` +#### Removed +- [mineralocorticoid](http://purl.obolibrary.org/obo/CHEBI_25354) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism." + +- [mineralocorticoid](http://purl.obolibrary.org/obo/CHEBI_25354) [label](http://www.w3.org/2000/01/rdf-schema#label) "mineralocorticoid" + +- [mineralocorticoid](http://purl.obolibrary.org/obo/CHEBI_25354) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mineralocorticoids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [mineralocorticoid](http://purl.obolibrary.org/obo/CHEBI_25354) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [mineralocorticoid](http://purl.obolibrary.org/obo/CHEBI_25354) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [mineralocorticoid](http://purl.obolibrary.org/obo/CHEBI_25354) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25354" + +- [mineralocorticoid](http://purl.obolibrary.org/obo/CHEBI_25354) SubClassOf [corticosteroid hormone](http://purl.obolibrary.org/obo/CHEBI_36699) + + + +### mineralocorticoid biosynthetic process `http://purl.obolibrary.org/obo/GO_0006705` +#### Removed +- [mineralocorticoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006705) SubClassOf [steroid hormone biosynthetic process](http://purl.obolibrary.org/obo/GO_0120178) + +#### Added +- [mineralocorticoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006705) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### mineralocorticoid catabolic process `http://purl.obolibrary.org/obo/GO_0006712` +#### Removed +- [mineralocorticoid catabolic process](http://purl.obolibrary.org/obo/GO_0006712) SubClassOf [steroid catabolic process](http://purl.obolibrary.org/obo/GO_0006706) + + + +### mixture `http://purl.obolibrary.org/obo/CHEBI_60004` +#### Removed +- [mixture](http://purl.obolibrary.org/obo/CHEBI_60004) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Mischung" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [mixture](http://purl.obolibrary.org/obo/CHEBI_60004) [label](http://www.w3.org/2000/01/rdf-schema#label) "mixture" + +- [mixture](http://purl.obolibrary.org/obo/CHEBI_60004) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [mixture](http://purl.obolibrary.org/obo/CHEBI_60004) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:60004" + +- [mixture](http://purl.obolibrary.org/obo/CHEBI_60004) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [mixture](http://purl.obolibrary.org/obo/CHEBI_60004) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind." + +- Class: [mixture](http://purl.obolibrary.org/obo/CHEBI_60004) + +- [mixture](http://purl.obolibrary.org/obo/CHEBI_60004) SubClassOf [chemical substance](http://purl.obolibrary.org/obo/CHEBI_59999) + + + +### modified amino acid transport `http://purl.obolibrary.org/obo/GO_0072337` +#### Removed +- [modified amino acid transport](http://purl.obolibrary.org/obo/GO_0072337) SubClassOf [nitrogen compound transport](http://purl.obolibrary.org/obo/GO_0071705) + +- [modified amino acid transport](http://purl.obolibrary.org/obo/GO_0072337) SubClassOf [organic substance transport](http://purl.obolibrary.org/obo/GO_0071702) + +#### Added +- [modified amino acid transport](http://purl.obolibrary.org/obo/GO_0072337) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### molecular entity `http://purl.obolibrary.org/obo/CHEBI_23367` +#### Removed +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "molekulare Entitaet" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "entidades moleculares" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "entite moleculaire" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "entidad molecular" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "entite moleculaire" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "molekulare Entitaet" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) [label](http://www.w3.org/2000/01/rdf-schema#label) "molecular entity" + +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "entidad molecular" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:23367" + +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "entidades moleculares" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- Class: [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) + +- [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) SubClassOf [chemical entity](http://purl.obolibrary.org/obo/CHEBI_24431) + + + +### molecular interaction relation helper property `http://purl.obolibrary.org/obo/RO_0002564` +#### Removed +- [molecular interaction relation helper property](http://purl.obolibrary.org/obo/RO_0002564) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [molecular interaction relation helper property](http://purl.obolibrary.org/obo/RO_0002564) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### molecular messenger `http://purl.obolibrary.org/obo/CHEBI_33280` +#### Removed +- [molecular messenger](http://purl.obolibrary.org/obo/CHEBI_33280) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [molecular messenger](http://purl.obolibrary.org/obo/CHEBI_33280) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chemical messenger" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [molecular messenger](http://purl.obolibrary.org/obo/CHEBI_33280) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33280" + +- [molecular messenger](http://purl.obolibrary.org/obo/CHEBI_33280) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [molecular messenger](http://purl.obolibrary.org/obo/CHEBI_33280) [label](http://www.w3.org/2000/01/rdf-schema#label) "molecular messenger" + +- Class: [molecular messenger](http://purl.obolibrary.org/obo/CHEBI_33280) + +- [molecular messenger](http://purl.obolibrary.org/obo/CHEBI_33280) SubClassOf [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) + + + +### molecular_function `http://purl.obolibrary.org/obo/GO_0003674` +#### Removed +- [molecular_function](http://purl.obolibrary.org/obo/GO_0003674) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pdt" + +#### Added +- [molecular_function](http://purl.obolibrary.org/obo/GO_0003674) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pdt" + + +### molecularly interacts with `http://purl.obolibrary.org/obo/RO_0002436` +#### Removed +- [molecularly interacts with](http://purl.obolibrary.org/obo/RO_0002436) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [molecularly interacts with](http://purl.obolibrary.org/obo/RO_0002436) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### molecule `http://purl.obolibrary.org/obo/CHEBI_25367` +#### Removed +- [molecule](http://purl.obolibrary.org/obo/CHEBI_25367) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [molecule](http://purl.obolibrary.org/obo/CHEBI_25367) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom." + +- [molecule](http://purl.obolibrary.org/obo/CHEBI_25367) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [molecule](http://purl.obolibrary.org/obo/CHEBI_25367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "molecules" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [molecule](http://purl.obolibrary.org/obo/CHEBI_25367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "neutral molecular compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [molecule](http://purl.obolibrary.org/obo/CHEBI_25367) [label](http://www.w3.org/2000/01/rdf-schema#label) "molecule" + +- [molecule](http://purl.obolibrary.org/obo/CHEBI_25367) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25367" + +- [molecule](http://purl.obolibrary.org/obo/CHEBI_25367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "molecula" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [molecule](http://purl.obolibrary.org/obo/CHEBI_25367) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "molecule" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [molecule](http://purl.obolibrary.org/obo/CHEBI_25367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Molekuel" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [molecule](http://purl.obolibrary.org/obo/CHEBI_25367) + +- [molecule](http://purl.obolibrary.org/obo/CHEBI_25367) SubClassOf [polyatomic entity](http://purl.obolibrary.org/obo/CHEBI_36357) + + + +### monoamine `http://purl.obolibrary.org/obo/CHEBI_63534` +#### Removed +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22153577" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "naturally occurring monoamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monoamines" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22218931" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22342987" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "naturally occurring monoamines" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:63534" + +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21993877" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) [label](http://www.w3.org/2000/01/rdf-schema#label) "monoamine" + +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21822758" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22005599" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22213370" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22371656" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22082101" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes." + +- Class: [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) + +- [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) SubClassOf [aralkylamino compound](http://purl.obolibrary.org/obo/CHEBI_64365) + + + +### monoamine molecular messenger `http://purl.obolibrary.org/obo/CHEBI_25375` +#### Removed +- [monoamine molecular messenger](http://purl.obolibrary.org/obo/CHEBI_25375) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monoamines" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monoamine molecular messenger](http://purl.obolibrary.org/obo/CHEBI_25375) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monamines" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monoamine molecular messenger](http://purl.obolibrary.org/obo/CHEBI_25375) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [monoamine molecular messenger](http://purl.obolibrary.org/obo/CHEBI_25375) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." + +- [monoamine molecular messenger](http://purl.obolibrary.org/obo/CHEBI_25375) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25375" + +- [monoamine molecular messenger](http://purl.obolibrary.org/obo/CHEBI_25375) [label](http://www.w3.org/2000/01/rdf-schema#label) "monoamine molecular messenger" + +- [monoamine molecular messenger](http://purl.obolibrary.org/obo/CHEBI_25375) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [monoamine molecular messenger](http://purl.obolibrary.org/obo/CHEBI_25375) + +- [monoamine molecular messenger](http://purl.obolibrary.org/obo/CHEBI_25375) SubClassOf [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) + +- [monoamine molecular messenger](http://purl.obolibrary.org/obo/CHEBI_25375) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [molecular messenger](http://purl.obolibrary.org/obo/CHEBI_33280) + + + +### monoamine transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0008504` +#### Removed +- [monoamine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008504) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-444160" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "VMAT1/2 can mediate the transport of biogenic amines" + +- [monoamine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008504) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-5660706" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "Defective SLC6A3 does not cotransport DA, Na+ from extracellular region to cytosol" + +- [monoamine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008504) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [monoamine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008504) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-380620" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "Reuptake of serotonin from the synapse" + +- [monoamine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008504) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [monoamine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008504) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0008504" + +- [monoamine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008504) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-372542" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "Loading of dopamine into synaptic veiscles" + +- [monoamine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008504) [label](http://www.w3.org/2000/01/rdf-schema#label) "monoamine transmembrane transporter activity" + +- [monoamine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008504) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0015201" + +- [monoamine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008504) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-380586" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "loading of Serotonin in synaptic vesicles" + +- [monoamine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008504) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-379393" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "SLC6A3 cotransports DA, Na+ from extracellular region to cytosol" + +- Class: [monoamine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008504) + +- [monoamine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008504) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534)) + +- [monoamine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008504) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) + +- [monoamine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008504) SubClassOf [active transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022804) + +- [monoamine transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008504) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [monoamine transport](http://purl.obolibrary.org/obo/GO_0015844) + + + +### monoamine transport `http://purl.obolibrary.org/obo/GO_0015844` +#### Removed +- [monoamine transport](http://purl.obolibrary.org/obo/GO_0015844) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [monoamine transport](http://purl.obolibrary.org/obo/GO_0015844) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [monoamine transport](http://purl.obolibrary.org/obo/GO_0015844) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015844" + +- [monoamine transport](http://purl.obolibrary.org/obo/GO_0015844) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0015873" + +- [monoamine transport](http://purl.obolibrary.org/obo/GO_0015844) [label](http://www.w3.org/2000/01/rdf-schema#label) "monoamine transport" + +- Class: [monoamine transport](http://purl.obolibrary.org/obo/GO_0015844) + +- [monoamine transport](http://purl.obolibrary.org/obo/GO_0015844) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534)) + +- [monoamine transport](http://purl.obolibrary.org/obo/GO_0015844) SubClassOf [organic substance transport](http://purl.obolibrary.org/obo/GO_0071702) + +- [monoamine transport](http://purl.obolibrary.org/obo/GO_0015844) SubClassOf [nitrogen compound transport](http://purl.obolibrary.org/obo/GO_0071705) + +- [monoamine transport](http://purl.obolibrary.org/obo/GO_0015844) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) + + + +### monoatomic cation `http://purl.obolibrary.org/obo/CHEBI_23906` +#### Removed +- [monoatomic cation](http://purl.obolibrary.org/obo/CHEBI_23906) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [monoatomic cation](http://purl.obolibrary.org/obo/CHEBI_23906) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [monoatomic cation](http://purl.obolibrary.org/obo/CHEBI_23906) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monoatomic cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monoatomic cation](http://purl.obolibrary.org/obo/CHEBI_23906) [label](http://www.w3.org/2000/01/rdf-schema#label) "monoatomic cation" + +- [monoatomic cation](http://purl.obolibrary.org/obo/CHEBI_23906) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:23906" + +- [monoatomic cation](http://purl.obolibrary.org/obo/CHEBI_23906) SubClassOf [monoatomic ion](http://purl.obolibrary.org/obo/CHEBI_24867) + +- [monoatomic cation](http://purl.obolibrary.org/obo/CHEBI_23906) SubClassOf [cation](http://purl.obolibrary.org/obo/CHEBI_36916) + + + +### monoatomic cation channel activity `http://purl.obolibrary.org/obo/GO_0005261` +#### Removed +- [monoatomic cation channel activity](http://purl.obolibrary.org/obo/GO_0005261) SubClassOf [monoatomic ion channel activity](http://purl.obolibrary.org/obo/GO_0005216) + +#### Added +- [monoatomic cation channel activity](http://purl.obolibrary.org/obo/GO_0005261) SubClassOf [channel activity](http://purl.obolibrary.org/obo/GO_0015267) + + +### monoatomic cation homeostasis `http://purl.obolibrary.org/obo/GO_0055080` +#### Removed +- [monoatomic cation homeostasis](http://purl.obolibrary.org/obo/GO_0055080) SubClassOf [monoatomic ion homeostasis](http://purl.obolibrary.org/obo/GO_0050801) + +#### Added +- [monoatomic cation homeostasis](http://purl.obolibrary.org/obo/GO_0055080) SubClassOf [chemical homeostasis](http://purl.obolibrary.org/obo/GO_0048878) + + +### monoatomic cation transmembrane transport `http://purl.obolibrary.org/obo/GO_0098655` +#### Removed +- [monoatomic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098655) SubClassOf [monoatomic ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0034220) + +#### Added +- [monoatomic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098655) SubClassOf [transmembrane transport](http://purl.obolibrary.org/obo/GO_0055085) + + +### monoatomic cation transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0008324` +#### Removed +- [monoatomic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008324) SubClassOf [monoatomic ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015075) + +#### Added +- [monoatomic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008324) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + +### monoatomic cation transport `http://purl.obolibrary.org/obo/GO_0006812` +#### Removed +- [monoatomic cation transport](http://purl.obolibrary.org/obo/GO_0006812) SubClassOf [monoatomic ion transport](http://purl.obolibrary.org/obo/GO_0006811) + +#### Added +- [monoatomic cation transport](http://purl.obolibrary.org/obo/GO_0006812) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### monoatomic dication `http://purl.obolibrary.org/obo/CHEBI_30412` +#### Removed +- [monoatomic dication](http://purl.obolibrary.org/obo/CHEBI_30412) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [monoatomic dication](http://purl.obolibrary.org/obo/CHEBI_30412) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monoatomic dications" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monoatomic dication](http://purl.obolibrary.org/obo/CHEBI_30412) [label](http://www.w3.org/2000/01/rdf-schema#label) "monoatomic dication" + +- [monoatomic dication](http://purl.obolibrary.org/obo/CHEBI_30412) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Divalent cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [monoatomic dication](http://purl.obolibrary.org/obo/CHEBI_30412) [mass](http://purl.obolibrary.org/obo/chebi/mass) "0.00000" + +- [monoatomic dication](http://purl.obolibrary.org/obo/CHEBI_30412) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:4665" + +- [monoatomic dication](http://purl.obolibrary.org/obo/CHEBI_30412) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[*++]" + +- [monoatomic dication](http://purl.obolibrary.org/obo/CHEBI_30412) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [monoatomic dication](http://purl.obolibrary.org/obo/CHEBI_30412) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+2" + +- [monoatomic dication](http://purl.obolibrary.org/obo/CHEBI_30412) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "divalent inorganic cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monoatomic dication](http://purl.obolibrary.org/obo/CHEBI_30412) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:30412" + +- [monoatomic dication](http://purl.obolibrary.org/obo/CHEBI_30412) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00572" + +- [monoatomic dication](http://purl.obolibrary.org/obo/CHEBI_30412) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:23856" + +- Class: [monoatomic dication](http://purl.obolibrary.org/obo/CHEBI_30412) + +- [monoatomic dication](http://purl.obolibrary.org/obo/CHEBI_30412) SubClassOf [monoatomic cation](http://purl.obolibrary.org/obo/CHEBI_23906) + + + +### monoatomic entity `http://purl.obolibrary.org/obo/CHEBI_33238` +#### Removed +- [monoatomic entity](http://purl.obolibrary.org/obo/CHEBI_33238) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [monoatomic entity](http://purl.obolibrary.org/obo/CHEBI_33238) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "atomic entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monoatomic entity](http://purl.obolibrary.org/obo/CHEBI_33238) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33238" + +- [monoatomic entity](http://purl.obolibrary.org/obo/CHEBI_33238) [label](http://www.w3.org/2000/01/rdf-schema#label) "monoatomic entity" + +- [monoatomic entity](http://purl.obolibrary.org/obo/CHEBI_33238) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A monoatomic entity is a molecular entity consisting of a single atom." + +- [monoatomic entity](http://purl.obolibrary.org/obo/CHEBI_33238) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monoatomic entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monoatomic entity](http://purl.obolibrary.org/obo/CHEBI_33238) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [monoatomic entity](http://purl.obolibrary.org/obo/CHEBI_33238) + +- [monoatomic entity](http://purl.obolibrary.org/obo/CHEBI_33238) SubClassOf [elemental molecular entity](http://purl.obolibrary.org/obo/CHEBI_33259) + + + +### monoatomic ion `http://purl.obolibrary.org/obo/CHEBI_24867` +#### Removed +- [monoatomic ion](http://purl.obolibrary.org/obo/CHEBI_24867) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [monoatomic ion](http://purl.obolibrary.org/obo/CHEBI_24867) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monoatomic ions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monoatomic ion](http://purl.obolibrary.org/obo/CHEBI_24867) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [monoatomic ion](http://purl.obolibrary.org/obo/CHEBI_24867) [label](http://www.w3.org/2000/01/rdf-schema#label) "monoatomic ion" + +- [monoatomic ion](http://purl.obolibrary.org/obo/CHEBI_24867) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24867" + +- [monoatomic ion](http://purl.obolibrary.org/obo/CHEBI_24867) SubClassOf [monoatomic entity](http://purl.obolibrary.org/obo/CHEBI_33238) + +- [monoatomic ion](http://purl.obolibrary.org/obo/CHEBI_24867) SubClassOf [ion](http://purl.obolibrary.org/obo/CHEBI_24870) + + + +### monoatomic ion channel complex `http://purl.obolibrary.org/obo/GO_0034702` +#### Removed +- [monoatomic ion channel complex](http://purl.obolibrary.org/obo/GO_0034702) [label](http://www.w3.org/2000/01/rdf-schema#label) "ion channel complex" + +- [monoatomic ion channel complex](http://purl.obolibrary.org/obo/GO_0034702) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:071673706X" + +#### Added +- [monoatomic ion channel complex](http://purl.obolibrary.org/obo/GO_0034702) [label](http://www.w3.org/2000/01/rdf-schema#label) "monoatomic ion channel complex" + +- [monoatomic ion channel complex](http://purl.obolibrary.org/obo/GO_0034702) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/20026"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [monoatomic ion channel complex](http://purl.obolibrary.org/obo/GO_0034702) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective monoatomic ion transport down its electrochemical gradient." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:071673706X" + + +### monoatomic monocation `http://purl.obolibrary.org/obo/CHEBI_25414` +#### Removed +- [monoatomic monocation](http://purl.obolibrary.org/obo/CHEBI_25414) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25414" + +- [monoatomic monocation](http://purl.obolibrary.org/obo/CHEBI_25414) [label](http://www.w3.org/2000/01/rdf-schema#label) "monoatomic monocation" + +- [monoatomic monocation](http://purl.obolibrary.org/obo/CHEBI_25414) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[*+]" + +- [monoatomic monocation](http://purl.obolibrary.org/obo/CHEBI_25414) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monovalent inorganic cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monoatomic monocation](http://purl.obolibrary.org/obo/CHEBI_25414) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [monoatomic monocation](http://purl.obolibrary.org/obo/CHEBI_25414) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [monoatomic monocation](http://purl.obolibrary.org/obo/CHEBI_25414) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+1" + +- [monoatomic monocation](http://purl.obolibrary.org/obo/CHEBI_25414) [mass](http://purl.obolibrary.org/obo/chebi/mass) "0.00000" + +- [monoatomic monocation](http://purl.obolibrary.org/obo/CHEBI_25414) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monoatomic monocations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [monoatomic monocation](http://purl.obolibrary.org/obo/CHEBI_25414) + +- [monoatomic monocation](http://purl.obolibrary.org/obo/CHEBI_25414) SubClassOf [monoatomic cation](http://purl.obolibrary.org/obo/CHEBI_23906) + + + +### monocarboxylic acid `http://purl.obolibrary.org/obo/CHEBI_25384` +#### Removed +- [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monocarboxylic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "monocarboxylic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt:" + +- [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An oxoacid containing a single carboxy group." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) [label](http://www.w3.org/2000/01/rdf-schema#label) "monocarboxylic acid" + +- [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monocarboxylic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25384" + +- Class: [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) + +- [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) SubClassOf [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) + +- [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) + + + +### monocarboxylic acid anion `http://purl.obolibrary.org/obo/CHEBI_35757` +#### Removed +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:3407" + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [label](http://www.w3.org/2000/01/rdf-schema#label) "monocarboxylic acid anion" + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00060" + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monocarboxylic acid anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CO2R" + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "43.98983" + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[O-]C([*])=O" + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13657" + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:25382" + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Carboxylate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a monocarboxylate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Monocarboxylate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35757" + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monocarboxylates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated." + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) [mass](http://purl.obolibrary.org/obo/chebi/mass) "44.01000" + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) SubClassOf [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) + +- [monocarboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_35757) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) + + + +### monocarboxylic acid binding `http://purl.obolibrary.org/obo/GO_0033293` +#### Removed +- [monocarboxylic acid binding](http://purl.obolibrary.org/obo/GO_0033293) SubClassOf [carboxylic acid binding](http://purl.obolibrary.org/obo/GO_0031406) + +#### Added +- [monocarboxylic acid binding](http://purl.obolibrary.org/obo/GO_0033293) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### monocarboxylic acid catabolic process `http://purl.obolibrary.org/obo/GO_0072329` +#### Removed +- [monocarboxylic acid catabolic process](http://purl.obolibrary.org/obo/GO_0072329) SubClassOf [carboxylic acid catabolic process](http://purl.obolibrary.org/obo/GO_0046395) + +#### Added +- [monocarboxylic acid catabolic process](http://purl.obolibrary.org/obo/GO_0072329) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### monocarboxylic acid transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0008028` +#### Removed +- [monocarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008028) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-429749" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "SLC5A8 transports monocarboxylates from extracellular region to cytosol" + +- [monocarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008028) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-433698" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol" + +- [monocarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008028) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0008028" + +- [monocarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008028) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [monocarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008028) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-9645220" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol" + +- [monocarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008028) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-5624211" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol" + +- [monocarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008028) [label](http://www.w3.org/2000/01/rdf-schema#label) "monocarboxylic acid transmembrane transporter activity" + +- [monocarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008028) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "monocarboxylate carrier" + +- [monocarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008028) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [monocarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008028) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "prostaglandin/thromboxane transporter activity" + +- [monocarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008028) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0008505" + +- Class: [monocarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008028) + +- [monocarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008028) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384)) + +- [monocarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008028) SubClassOf [organic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005342) + +- [monocarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008028) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [monocarboxylic acid](http://purl.obolibrary.org/obo/CHEBI_25384) + +- [monocarboxylic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008028) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [monocarboxylic acid transport](http://purl.obolibrary.org/obo/GO_0015718) + + + +### monocyclic heteroarene `http://purl.obolibrary.org/obo/CHEBI_38179` +#### Removed +- [monocyclic heteroarene](http://purl.obolibrary.org/obo/CHEBI_38179) [label](http://www.w3.org/2000/01/rdf-schema#label) "monocyclic heteroarene" + +- [monocyclic heteroarene](http://purl.obolibrary.org/obo/CHEBI_38179) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:38179" + +- [monocyclic heteroarene](http://purl.obolibrary.org/obo/CHEBI_38179) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [monocyclic heteroarene](http://purl.obolibrary.org/obo/CHEBI_38179) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [monocyclic heteroarene](http://purl.obolibrary.org/obo/CHEBI_38179) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monocyclic heteroarenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [monocyclic heteroarene](http://purl.obolibrary.org/obo/CHEBI_38179) + +- [monocyclic heteroarene](http://purl.obolibrary.org/obo/CHEBI_38179) SubClassOf [heteroarene](http://purl.obolibrary.org/obo/CHEBI_33833) + + + +### monoisotopicmass `http://purl.obolibrary.org/obo/chebi/monoisotopicmass` +#### Removed +- AnnotationProperty: [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) + + + +### mononuclear parent hydride `http://purl.obolibrary.org/obo/CHEBI_37176` +#### Removed +- [mononuclear parent hydride](http://purl.obolibrary.org/obo/CHEBI_37176) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mononuclear hydrides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [mononuclear parent hydride](http://purl.obolibrary.org/obo/CHEBI_37176) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [mononuclear parent hydride](http://purl.obolibrary.org/obo/CHEBI_37176) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [mononuclear parent hydride](http://purl.obolibrary.org/obo/CHEBI_37176) [label](http://www.w3.org/2000/01/rdf-schema#label) "mononuclear parent hydride" + +- [mononuclear parent hydride](http://purl.obolibrary.org/obo/CHEBI_37176) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "mononuclear parent hydrides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [mononuclear parent hydride](http://purl.obolibrary.org/obo/CHEBI_37176) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:37176" + +- [mononuclear parent hydride](http://purl.obolibrary.org/obo/CHEBI_37176) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mononuclear hydride" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [mononuclear parent hydride](http://purl.obolibrary.org/obo/CHEBI_37176) + +- [mononuclear parent hydride](http://purl.obolibrary.org/obo/CHEBI_37176) SubClassOf [hydrides](http://purl.obolibrary.org/obo/CHEBI_33692) + + + +### monosaccharide `http://purl.obolibrary.org/obo/CHEBI_35381` +#### Removed +- [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:25407" + +- [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Monosaccharide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35381" + +- [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) [label](http://www.w3.org/2000/01/rdf-schema#label) "monosaccharide" + +- [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monosacarido" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Monosacharid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Monosaccharid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:6984" + +- [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monosacaridos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group." + +- [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "monosaccharides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C06698" + +- [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) + +- [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) SubClassOf [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) + + + +### monosaccharide binding `http://purl.obolibrary.org/obo/GO_0048029` +#### Removed +- [monosaccharide binding](http://purl.obolibrary.org/obo/GO_0048029) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0048029" + +- [monosaccharide binding](http://purl.obolibrary.org/obo/GO_0048029) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jid" + +- [monosaccharide binding](http://purl.obolibrary.org/obo/GO_0048029) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [monosaccharide binding](http://purl.obolibrary.org/obo/GO_0048029) [label](http://www.w3.org/2000/01/rdf-schema#label) "monosaccharide binding" + +- Class: [monosaccharide binding](http://purl.obolibrary.org/obo/GO_0048029) + +- [monosaccharide binding](http://purl.obolibrary.org/obo/GO_0048029) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381)) + +- [monosaccharide binding](http://purl.obolibrary.org/obo/GO_0048029) SubClassOf [carbohydrate binding](http://purl.obolibrary.org/obo/GO_0030246) + +- [monosaccharide binding](http://purl.obolibrary.org/obo/GO_0048029) SubClassOf [small molecule binding](http://purl.obolibrary.org/obo/GO_0036094) + +- [monosaccharide binding](http://purl.obolibrary.org/obo/GO_0048029) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) + + + +### monosaccharide biosynthetic process `http://purl.obolibrary.org/obo/GO_0046364` +#### Removed +- [monosaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0046364) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "monosaccharide anabolism" + +- [monosaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0046364) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046364" + +- [monosaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0046364) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [monosaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0046364) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "monosaccharide synthesis" + +- [monosaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0046364) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [monosaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0046364) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "monosaccharide biosynthesis" + +- [monosaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0046364) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "monosaccharide formation" + +- [monosaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0046364) [label](http://www.w3.org/2000/01/rdf-schema#label) "monosaccharide biosynthetic process" + +- Class: [monosaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0046364) + +- [monosaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0046364) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381)) + +- [monosaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0046364) SubClassOf [small molecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0044283) + +- [monosaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0046364) SubClassOf [carbohydrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0016051) + +- [monosaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0046364) SubClassOf [monosaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005996) + +- [monosaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0046364) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) + + + +### monosaccharide catabolic process `http://purl.obolibrary.org/obo/GO_0046365` +#### Removed +- [monosaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0046365) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "monosaccharide degradation" + +- [monosaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0046365) [label](http://www.w3.org/2000/01/rdf-schema#label) "monosaccharide catabolic process" + +- [monosaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0046365) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "monosaccharide catabolism" + +- [monosaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0046365) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046365" + +- [monosaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0046365) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [monosaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0046365) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "monosaccharide breakdown" + +- [monosaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0046365) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [monosaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0046365) + +- [monosaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0046365) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381)) + +- [monosaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0046365) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) + +- [monosaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0046365) SubClassOf [small molecule catabolic process](http://purl.obolibrary.org/obo/GO_0044282) + +- [monosaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0046365) SubClassOf [monosaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005996) + +- [monosaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0046365) SubClassOf [carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0016052) + + + +### monosaccharide metabolic process `http://purl.obolibrary.org/obo/GO_0005996` +#### Removed +- [monosaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005996) [label](http://www.w3.org/2000/01/rdf-schema#label) "monosaccharide metabolic process" + +- [monosaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005996) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [monosaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005996) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [monosaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005996) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "monosaccharide metabolism" + +- [monosaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005996) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0005996" + +- Class: [monosaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005996) + +- [monosaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005996) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381)) + +- [monosaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005996) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) + +- [monosaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005996) SubClassOf [carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0005975) + +- [monosaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005996) SubClassOf [small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0044281) + + + +### monosaccharide transmembrane transport `http://purl.obolibrary.org/obo/GO_0015749` +#### Removed +- [monosaccharide transmembrane transport](http://purl.obolibrary.org/obo/GO_0015749) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:vw" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000069" + +- [monosaccharide transmembrane transport](http://purl.obolibrary.org/obo/GO_0015749) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "vw" + +- [monosaccharide transmembrane transport](http://purl.obolibrary.org/obo/GO_0015749) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:1905950" + +- [monosaccharide transmembrane transport](http://purl.obolibrary.org/obo/GO_0015749) [label](http://www.w3.org/2000/01/rdf-schema#label) "monosaccharide transmembrane transport" + +- [monosaccharide transmembrane transport](http://purl.obolibrary.org/obo/GO_0015749) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015749" + +- [monosaccharide transmembrane transport](http://purl.obolibrary.org/obo/GO_0015749) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [monosaccharide transmembrane transport](http://purl.obolibrary.org/obo/GO_0015749) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2017-02-19T10:41:27Z" + +- [monosaccharide transmembrane transport](http://purl.obolibrary.org/obo/GO_0015749) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monosaccharide transport" + +- Class: [monosaccharide transmembrane transport](http://purl.obolibrary.org/obo/GO_0015749) + +- [monosaccharide transmembrane transport](http://purl.obolibrary.org/obo/GO_0015749) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([results in transport across](http://purl.obolibrary.org/obo/RO_0002342) some [membrane](http://purl.obolibrary.org/obo/GO_0016020)) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381)) + +- [monosaccharide transmembrane transport](http://purl.obolibrary.org/obo/GO_0015749) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) + +- [monosaccharide transmembrane transport](http://purl.obolibrary.org/obo/GO_0015749) SubClassOf [carbohydrate transmembrane transport](http://purl.obolibrary.org/obo/GO_0034219) + + + +### monosaccharide transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015145` +#### Removed +- [monosaccharide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015145) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of a monosaccharide from one side of a membrane to the other." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0815340729" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_transport" + +- [monosaccharide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015145) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015145" + +- [monosaccharide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015145) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [monosaccharide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015145) [label](http://www.w3.org/2000/01/rdf-schema#label) "monosaccharide transmembrane transporter activity" + +- Class: [monosaccharide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015145) + +- [monosaccharide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015145) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381)) + +- [monosaccharide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015145) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [monosaccharide transmembrane transport](http://purl.obolibrary.org/obo/GO_0015749) + +- [monosaccharide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015145) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) + +- [monosaccharide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015145) SubClassOf [sugar transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051119) + + + +### monovalent inorganic anion `http://purl.obolibrary.org/obo/CHEBI_79389` +#### Removed +- [monovalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79389) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:79389" + +- [monovalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79389) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [monovalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79389) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monovalent inorganic anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [monovalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79389) [label](http://www.w3.org/2000/01/rdf-schema#label) "monovalent inorganic anion" + +- [monovalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79389) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [monovalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79389) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any inorganic anion with a valency of one." + +- Class: [monovalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79389) + +- [monovalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79389) SubClassOf [inorganic anion](http://purl.obolibrary.org/obo/CHEBI_24834) + + + +### monovalent inorganic cation `http://purl.obolibrary.org/obo/CHEBI_60242` +#### Removed +- [monovalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_60242) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:60242" + +- [monovalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_60242) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [monovalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_60242) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one." + +- [monovalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_60242) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a monovalent cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [monovalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_60242) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [monovalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_60242) [label](http://www.w3.org/2000/01/rdf-schema#label) "monovalent inorganic cation" + +- Class: [monovalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_60242) + +- [monovalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_60242) SubClassOf [inorganic cation](http://purl.obolibrary.org/obo/CHEBI_36915) + + + +### morula cell `http://purl.obolibrary.org/obo/CL_0000360` +#### Removed +- [morula cell](http://purl.obolibrary.org/obo/CL_0000360) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### motile cell `http://purl.obolibrary.org/obo/CL_0000219` +#### Removed +- [motile cell](http://purl.obolibrary.org/obo/CL_0000219) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### mouse metabolite `http://purl.obolibrary.org/obo/CHEBI_75771` +#### Removed +- [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Mus musculus metabolite" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:75771" + +- [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus)." + +- [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) [label](http://www.w3.org/2000/01/rdf-schema#label) "mouse metabolite" + +- [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mouse metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Mus musculus metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) SubClassOf [mammalian metabolite](http://purl.obolibrary.org/obo/CHEBI_75768) + + + +### mucopolysaccharide `http://purl.obolibrary.org/obo/CHEBI_37395` +#### Removed +- [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mucopolisacarido" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Mucopolysaccharid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) [label](http://www.w3.org/2000/01/rdf-schema#label) "mucopolysaccharide" + +- [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C05114" + +- [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mucopolisacaridos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "mucopolysaccharides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:37395" + +- [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any of the group of polysaccharides composed of alternating units from uronic acids and glycosamines, and commonly partially esterified with sulfuric acid." + +- [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:7011" + +- [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Mucopolysaccharide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Mukopolysaccharid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:25425" + +- [mucopolysaccharide](http://purl.obolibrary.org/obo/CHEBI_37395) SubClassOf [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) + + + +### mucopolysaccharide metabolic process `http://purl.obolibrary.org/obo/GO_1903510` +#### Removed +- [mucopolysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903510) SubClassOf [glycosaminoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0030203) + +#### Added +- [mucopolysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_1903510) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### mucosa of lobular bronchiole `http://purl.obolibrary.org/obo/UBERON_8600002` +#### Removed +- [mucosa of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600002) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](http://orcid.org/0000-0001-6677-8489) + +#### Added +- [mucosa of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600002) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + + +### mucous cell of stomach `http://purl.obolibrary.org/obo/CL_0002180` +#### Removed +- [mucous cell of stomach](http://purl.obolibrary.org/obo/CL_0002180) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000404" + + + +### mucous neck cell of gastric gland `http://purl.obolibrary.org/obo/CL_0002181` +#### Removed +- [mucous neck cell of gastric gland](http://purl.obolibrary.org/obo/CL_0002181) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000401" + + + +### mucus secreting cell of bronchus submucosal gland `http://purl.obolibrary.org/obo/CL_4033022` + +#### Added +- [mucus secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033022) [date](http://purl.org/dc/terms/date) "2023-03-16T15:12:52Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [mucus secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033022) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A mucus secreting cell of a submucosal gland of the bronchus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19965983" + +- [mucus secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033022) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-9185-3994](https://orcid.org/0000-0002-9185-3994) + +- [mucus secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033022) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- [mucus secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033022) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "bronchial gland mucous cell" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:5487122" + +- [mucus secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033022) [label](http://www.w3.org/2000/01/rdf-schema#label) "mucus secreting cell of bronchus submucosal gland" + +- Class: [mucus secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033022) + +- [mucus secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033022) EquivalentTo [mucus secreting cell](http://purl.obolibrary.org/obo/CL_0000319) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [bronchus submucosal gland](http://purl.obolibrary.org/obo/UBERON_8410043)) + +- [mucus secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033022) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [bronchus submucosal gland](http://purl.obolibrary.org/obo/UBERON_8410043) + +- [mucus secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033022) SubClassOf [exocrine cell](http://purl.obolibrary.org/obo/CL_0000152) + +- [mucus secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033022) SubClassOf [mucus secreting cell](http://purl.obolibrary.org/obo/CL_0000319) + + +### mucus secreting cell of trachea gland `http://purl.obolibrary.org/obo/CL_4033020` + +#### Added +- [mucus secreting cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033020) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-9185-3994](https://orcid.org/0000-0002-9185-3994) + +- [mucus secreting cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033020) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A mucus secreting cell that is part of a submucosal gland of the trachea." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:29656943" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18931053" + +- [mucus secreting cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033020) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tracheal submucosal gland mucous cell" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18931053" + +- [mucus secreting cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033020) [label](http://www.w3.org/2000/01/rdf-schema#label) "mucus secreting cell of trachea gland" + +- [mucus secreting cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033020) [date](http://purl.org/dc/terms/date) "2023-03-16T13:03:13Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [mucus secreting cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033020) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- Class: [mucus secreting cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033020) + +- [mucus secreting cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033020) EquivalentTo [mucus secreting cell](http://purl.obolibrary.org/obo/CL_0000319) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [trachea gland](http://purl.obolibrary.org/obo/UBERON_0005203)) + +- [mucus secreting cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033020) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [trachea gland](http://purl.obolibrary.org/obo/UBERON_0005203) + +- [mucus secreting cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033020) SubClassOf [exocrine cell](http://purl.obolibrary.org/obo/CL_0000152) + +- [mucus secreting cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033020) SubClassOf [mucus secreting cell](http://purl.obolibrary.org/obo/CL_0000319) + + +### multicellular organismal-level iron ion homeostasis `http://purl.obolibrary.org/obo/GO_0060586` +#### Removed +- [multicellular organismal-level iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0060586) SubClassOf [iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0055072) + +- [multicellular organismal-level iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0060586) SubClassOf [multicellular organismal-level chemical homeostasis](http://purl.obolibrary.org/obo/GO_0140962) + +#### Added +- [multicellular organismal-level iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0060586) SubClassOf [multicellular organismal-level homeostasis](http://purl.obolibrary.org/obo/GO_0048871) + +- [multicellular organismal-level iron ion homeostasis](http://purl.obolibrary.org/obo/GO_0060586) SubClassOf [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [iron cation](http://purl.obolibrary.org/obo/CHEBI_24875) + + +### multicellular organismal-level water homeostasis `http://purl.obolibrary.org/obo/GO_0050891` +#### Removed +- [multicellular organismal-level water homeostasis](http://purl.obolibrary.org/obo/GO_0050891) SubClassOf [water homeostasis](http://purl.obolibrary.org/obo/GO_0030104) + +- [multicellular organismal-level water homeostasis](http://purl.obolibrary.org/obo/GO_0050891) SubClassOf [multicellular organismal-level chemical homeostasis](http://purl.obolibrary.org/obo/GO_0140962) + +#### Added +- [multicellular organismal-level water homeostasis](http://purl.obolibrary.org/obo/GO_0050891) SubClassOf [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [water](http://purl.obolibrary.org/obo/CHEBI_15377) + +- [multicellular organismal-level water homeostasis](http://purl.obolibrary.org/obo/GO_0050891) SubClassOf [multicellular organismal-level homeostasis](http://purl.obolibrary.org/obo/GO_0048871) + + +### muscarinic agonist `http://purl.obolibrary.org/obo/CHEBI_38325` +#### Removed +- [muscarinic agonist](http://purl.obolibrary.org/obo/CHEBI_38325) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "muscarinic agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [muscarinic agonist](http://purl.obolibrary.org/obo/CHEBI_38325) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any drug that binds to and activates a muscarinic cholinergic receptor." + +- [muscarinic agonist](http://purl.obolibrary.org/obo/CHEBI_38325) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "muscarinic acetylcholine receptor agonist" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [muscarinic agonist](http://purl.obolibrary.org/obo/CHEBI_38325) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [muscarinic agonist](http://purl.obolibrary.org/obo/CHEBI_38325) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "muscarinic cholinergic agonist" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [muscarinic agonist](http://purl.obolibrary.org/obo/CHEBI_38325) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [muscarinic agonist](http://purl.obolibrary.org/obo/CHEBI_38325) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "muscarinic cholinergic agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [muscarinic agonist](http://purl.obolibrary.org/obo/CHEBI_38325) [label](http://www.w3.org/2000/01/rdf-schema#label) "muscarinic agonist" + +- [muscarinic agonist](http://purl.obolibrary.org/obo/CHEBI_38325) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:38325" + +- Class: [muscarinic agonist](http://purl.obolibrary.org/obo/CHEBI_38325) + +- [muscarinic agonist](http://purl.obolibrary.org/obo/CHEBI_38325) SubClassOf [cholinergic agonist](http://purl.obolibrary.org/obo/CHEBI_38324) + + + +### myelinating glial cell `http://purl.obolibrary.org/obo/CL_4023154` +#### Removed +- [myelinating glial cell](http://purl.obolibrary.org/obo/CL_4023154) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000328" + + + +### myeloblast `http://purl.obolibrary.org/obo/CL_0000835` +#### Removed +- [myeloblast](http://purl.obolibrary.org/obo/CL_0000835) EquivalentTo [granulocytopoietic cell](http://purl.obolibrary.org/obo/CL_0002191) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [basophilic cytoplasm](http://purl.obolibrary.org/obo/CL_0017503)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [euchromatin](http://purl.obolibrary.org/obo/GO_0000791)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582)) + +- [myeloblast](http://purl.obolibrary.org/obo/CL_0000835) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582) + +#### Added +- [myeloblast](http://purl.obolibrary.org/obo/CL_0000835) EquivalentTo [granulocytopoietic cell](http://purl.obolibrary.org/obo/CL_0002191) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [basophilic cytoplasm](http://purl.obolibrary.org/obo/CL_0017503)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [euchromatin](http://purl.obolibrary.org/obo/GO_0000791)) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582)) + +- [myeloblast](http://purl.obolibrary.org/obo/CL_0000835) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582) + + +### myeloid dendritic cell `http://purl.obolibrary.org/obo/CL_0000782` +#### Removed +- [myeloid dendritic cell](http://purl.obolibrary.org/obo/CL_0000782) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([develops from](http://purl.obolibrary.org/obo/RO_0002202) some [myeloid cell](http://purl.obolibrary.org/obo/CL_0000763)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) + +- [myeloid dendritic cell](http://purl.obolibrary.org/obo/CL_0000782) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865) + +#### Added +- [myeloid dendritic cell](http://purl.obolibrary.org/obo/CL_0000782) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) and ([develops from](http://purl.obolibrary.org/obo/RO_0002202) some [myeloid cell](http://purl.obolibrary.org/obo/CL_0000763)) + +- [myeloid dendritic cell](http://purl.obolibrary.org/obo/CL_0000782) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865) + + +### myocardial endocrine cell of septal division of left branch of atrioventricular bundle `http://purl.obolibrary.org/obo/CL_1000375` + +#### Added +- [myocardial endocrine cell of septal division of left branch of atrioventricular bundle](http://purl.obolibrary.org/obo/CL_1000375) SubClassOf [transversely striated visceral muscle cell](http://purl.obolibrary.org/obo/CL_0008009) + + +### myocyte of atrioventricular node `http://purl.obolibrary.org/obo/CL_1000410` + +#### Added +- [myocyte of atrioventricular node](http://purl.obolibrary.org/obo/CL_1000410) SubClassOf [transversely striated visceral muscle cell](http://purl.obolibrary.org/obo/CL_0008009) + + +### myocyte of sinoatrial node `http://purl.obolibrary.org/obo/CL_1000409` + +#### Added +- [myocyte of sinoatrial node](http://purl.obolibrary.org/obo/CL_1000409) SubClassOf [transversely striated visceral muscle cell](http://purl.obolibrary.org/obo/CL_0008009) + + +### myoepithelial cell of trachea gland `http://purl.obolibrary.org/obo/CL_4033021` + +#### Added +- [myoepithelial cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033021) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-9185-3994](https://orcid.org/0000-0002-9185-3994) + +- [myoepithelial cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033021) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A myoepithelial cell that is part of a submucosal gland of the trachea." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:29656943" + +- [myoepithelial cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033021) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- [myoepithelial cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033021) [label](http://www.w3.org/2000/01/rdf-schema#label) "myoepithelial cell of trachea gland" + +- [myoepithelial cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033021) [date](http://purl.org/dc/terms/date) "2023-03-16T13:36:43Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- Class: [myoepithelial cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033021) + +- [myoepithelial cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033021) EquivalentTo [myoepithelial cell](http://purl.obolibrary.org/obo/CL_0000185) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [trachea gland](http://purl.obolibrary.org/obo/UBERON_0005203)) + +- [myoepithelial cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033021) SubClassOf [tracheal epithelial cell](http://purl.obolibrary.org/obo/CL_0000307) + +- [myoepithelial cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033021) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [trachea gland](http://purl.obolibrary.org/obo/UBERON_0005203) + +- [myoepithelial cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033021) SubClassOf [connective tissue cell](http://purl.obolibrary.org/obo/CL_0002320) + +- [myoepithelial cell of trachea gland](http://purl.obolibrary.org/obo/CL_4033021) SubClassOf [myoepithelial cell](http://purl.obolibrary.org/obo/CL_0000185) + + +### myotube `http://purl.obolibrary.org/obo/CL_0002372` +#### Removed +- [myotube](http://purl.obolibrary.org/obo/CL_0002372) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000369" + + + +### naive B cell `http://purl.obolibrary.org/obo/CL_0000788` +#### Removed +- [naive B cell](http://purl.obolibrary.org/obo/CL_0000788) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [B cell affinity maturation](http://purl.obolibrary.org/obo/GO_0002344)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) + +- [naive B cell](http://purl.obolibrary.org/obo/CL_0000788) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [B cell affinity maturation](http://purl.obolibrary.org/obo/GO_0002344) + +- [naive B cell](http://purl.obolibrary.org/obo/CL_0000788) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963) + +#### Added +- [naive B cell](http://purl.obolibrary.org/obo/CL_0000788) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [B cell affinity maturation](http://purl.obolibrary.org/obo/GO_0002344)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) + +- [naive B cell](http://purl.obolibrary.org/obo/CL_0000788) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963) + +- [naive B cell](http://purl.obolibrary.org/obo/CL_0000788) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [B cell affinity maturation](http://purl.obolibrary.org/obo/GO_0002344) + + +### naive CCR4-positive regulatory T cell `http://purl.obolibrary.org/obo/CL_0001045` +#### Removed +- [naive CCR4-positive regulatory T cell](http://purl.obolibrary.org/obo/CL_0001045) EquivalentTo [naive regulatory T cell](http://purl.obolibrary.org/obo/CL_0002677) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 4](http://purl.obolibrary.org/obo/PR_000001200)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) + +- [naive CCR4-positive regulatory T cell](http://purl.obolibrary.org/obo/CL_0001045) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017) + +#### Added +- [naive CCR4-positive regulatory T cell](http://purl.obolibrary.org/obo/CL_0001045) EquivalentTo [naive regulatory T cell](http://purl.obolibrary.org/obo/CL_0002677) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 4](http://purl.obolibrary.org/obo/PR_000001200)) + +- [naive CCR4-positive regulatory T cell](http://purl.obolibrary.org/obo/CL_0001045) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017) + + +### naive thymus-derived CD4-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000895` +#### Removed +- [naive thymus-derived CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000895) EquivalentTo [CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000624) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) + +- [naive thymus-derived CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000895) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + +#### Added +- [naive thymus-derived CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000895) EquivalentTo [CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000624) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) + +- [naive thymus-derived CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000895) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + + +### naive thymus-derived CD8-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000900` +#### Removed +- [naive thymus-derived CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000900) EquivalentTo [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) + +- [naive thymus-derived CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000900) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + +#### Added +- [naive thymus-derived CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000900) EquivalentTo [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) + +- [naive thymus-derived CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000900) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380) + + +### natural helper lymphocyte `http://purl.obolibrary.org/obo/CL_0002679` +#### Removed +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) EquivalentTo [lymphocyte](http://purl.obolibrary.org/obo/CL_0000542) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [alpha-beta T cell receptor complex](http://purl.obolibrary.org/obo/GO_0042105)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) + +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [alpha-beta T cell receptor complex](http://purl.obolibrary.org/obo/GO_0042105) + +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874) + +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013) + +#### Added +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) EquivalentTo [lymphocyte](http://purl.obolibrary.org/obo/CL_0000542) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [alpha-beta T cell receptor complex](http://purl.obolibrary.org/obo/GO_0042105)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) + +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013) + +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [alpha-beta T cell receptor complex](http://purl.obolibrary.org/obo/GO_0042105) + +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874) + +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [natural helper lymphocyte](http://purl.obolibrary.org/obo/CL_0002679) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + + +### natural killer cell `http://purl.obolibrary.org/obo/CL_0000623` +#### Removed +- [natural killer cell](http://purl.obolibrary.org/obo/CL_0000623) EquivalentTo [group 1 innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001067) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [natural killer cell mediated immunity](http://purl.obolibrary.org/obo/GO_0002228)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [regulation of immune response](http://purl.obolibrary.org/obo/GO_0050776)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) + +- [natural killer cell](http://purl.obolibrary.org/obo/CL_0000623) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [natural killer cell](http://purl.obolibrary.org/obo/CL_0000623) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +#### Added +- [natural killer cell](http://purl.obolibrary.org/obo/CL_0000623) EquivalentTo [group 1 innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001067) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [natural killer cell mediated immunity](http://purl.obolibrary.org/obo/GO_0002228)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [regulation of immune response](http://purl.obolibrary.org/obo/GO_0050776)) + +- [natural killer cell](http://purl.obolibrary.org/obo/CL_0000623) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [natural killer cell](http://purl.obolibrary.org/obo/CL_0000623) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + + +### natural product fundamental parent `http://purl.obolibrary.org/obo/CHEBI_35507` +#### Removed +- [natural product fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35507) [label](http://www.w3.org/2000/01/rdf-schema#label) "natural product fundamental parent" + +- [natural product fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35507) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [natural product fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35507) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [natural product fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35507) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "natural product fundamental parents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [natural product fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35507) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35507" + +- Class: [natural product fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35507) + +- [natural product fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35507) SubClassOf [organic fundamental parent](http://purl.obolibrary.org/obo/CHEBI_33245) + + + +### negative regulation of CD4 production `http://purl.obolibrary.org/obo/GO_0045225` + +#### Added +- [negative regulation of CD4 production](http://purl.obolibrary.org/obo/GO_0045225) SubClassOf [negative regulation of protein metabolic process](http://purl.obolibrary.org/obo/GO_0051248) + + +### negative regulation of DNA biosynthetic process `http://purl.obolibrary.org/obo/GO_2000279` +#### Removed +- [negative regulation of DNA biosynthetic process](http://purl.obolibrary.org/obo/GO_2000279) SubClassOf [negative regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031327) + +- [negative regulation of DNA biosynthetic process](http://purl.obolibrary.org/obo/GO_2000279) SubClassOf [negative regulation of macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0010558) + +#### Added +- [negative regulation of DNA biosynthetic process](http://purl.obolibrary.org/obo/GO_2000279) SubClassOf [negative regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009890) + + +### negative regulation of DNA catabolic process `http://purl.obolibrary.org/obo/GO_1903625` +#### Removed +- [negative regulation of DNA catabolic process](http://purl.obolibrary.org/obo/GO_1903625) SubClassOf [negative regulation of cellular catabolic process](http://purl.obolibrary.org/obo/GO_0031330) + +#### Added +- [negative regulation of DNA catabolic process](http://purl.obolibrary.org/obo/GO_1903625) SubClassOf [negative regulation of catabolic process](http://purl.obolibrary.org/obo/GO_0009895) + + +### negative regulation of DNA metabolic process `http://purl.obolibrary.org/obo/GO_0051053` +#### Removed +- [negative regulation of DNA metabolic process](http://purl.obolibrary.org/obo/GO_0051053) SubClassOf [negative regulation of nucleobase-containing compound metabolic process](http://purl.obolibrary.org/obo/GO_0045934) + + + +### negative regulation of RNA biosynthetic process `http://purl.obolibrary.org/obo/GO_1902679` +#### Removed +- [negative regulation of RNA biosynthetic process](http://purl.obolibrary.org/obo/GO_1902679) SubClassOf [negative regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031327) + +- [negative regulation of RNA biosynthetic process](http://purl.obolibrary.org/obo/GO_1902679) SubClassOf [negative regulation of macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0010558) + +#### Added +- [negative regulation of RNA biosynthetic process](http://purl.obolibrary.org/obo/GO_1902679) SubClassOf [negative regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009890) + + +### negative regulation of RNA catabolic process `http://purl.obolibrary.org/obo/GO_1902369` +#### Removed +- [negative regulation of RNA catabolic process](http://purl.obolibrary.org/obo/GO_1902369) SubClassOf [negative regulation of cellular catabolic process](http://purl.obolibrary.org/obo/GO_0031330) + +#### Added +- [negative regulation of RNA catabolic process](http://purl.obolibrary.org/obo/GO_1902369) SubClassOf [negative regulation of catabolic process](http://purl.obolibrary.org/obo/GO_0009895) + +- [negative regulation of RNA catabolic process](http://purl.obolibrary.org/obo/GO_1902369) SubClassOf [negative regulation of macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0010605) + + +### negative regulation of RNA metabolic process `http://purl.obolibrary.org/obo/GO_0051253` +#### Removed +- [negative regulation of RNA metabolic process](http://purl.obolibrary.org/obo/GO_0051253) SubClassOf [negative regulation of macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0010605) + +- [negative regulation of RNA metabolic process](http://purl.obolibrary.org/obo/GO_0051253) SubClassOf [negative regulation of nucleobase-containing compound metabolic process](http://purl.obolibrary.org/obo/GO_0045934) + +#### Added +- [negative regulation of RNA metabolic process](http://purl.obolibrary.org/obo/GO_0051253) SubClassOf [negative regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009892) + + +### negative regulation of acetate catabolic process `http://purl.obolibrary.org/obo/GO_0045753` +#### Removed +- [negative regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045753) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of acetate catabolic process" + +- [negative regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045753) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of acetate catabolic process" + +- [negative regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045753) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of acetate catabolic process" + +- [negative regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045753) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of acetate degradation" + +- [negative regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045753) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of acetate catabolism" + +- [negative regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045753) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of acetate catabolic process" + +- [negative regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045753) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of acetate catabolic process" + +- [negative regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045753) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of acetate breakdown" + +- [negative regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045753) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0045753" + +- [negative regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045753) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [negative regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045753) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [negative regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045753) + +- [negative regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045753) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733)) + +- [negative regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045753) SubClassOf [regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045734) + +- [negative regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045753) SubClassOf [negative regulation of cellular catabolic process](http://purl.obolibrary.org/obo/GO_0031330) + +- [negative regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045753) SubClassOf [negative regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062014) + +- [negative regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045753) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733) + + + +### negative regulation of acetylcholine-gated cation channel activity `http://purl.obolibrary.org/obo/GO_1903049` + +#### Added +- [negative regulation of acetylcholine-gated cation channel activity](http://purl.obolibrary.org/obo/GO_1903049) SubClassOf [negative regulation of ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0032413) + + +### negative regulation of alcohol biosynthetic process `http://purl.obolibrary.org/obo/GO_1902931` +#### Removed +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of alcohol formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of alcohol anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of alcohol formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of alcohol anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-04-22T21:55:13Z" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of alcohol synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of alcohol biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of alcohol biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of alcohol synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of alcohol biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of alcohol biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of alcohol formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of alcohol anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of alcohol formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of alcohol synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902931" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of alcohol biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23332010" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of alcohol biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of alcohol anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of alcohol biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of alcohol biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of alcohol anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "negative regulation of solventogenesis" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of alcohol biosynthetic process" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of alcohol synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of alcohol formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of alcohol biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of alcohol synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165)) + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) SubClassOf [negative regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062014) + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) SubClassOf [negative regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009890) + +- [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) SubClassOf [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) + + + +### negative regulation of aldosterone biosynthetic process `http://purl.obolibrary.org/obo/GO_0032348` +#### Removed +- [negative regulation of aldosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_0032348) SubClassOf [negative regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902931) + + + +### negative regulation of alkane biosynthetic process `http://purl.obolibrary.org/obo/GO_1901578` +#### Removed +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of alkane biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of alkane biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of alkane synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of alkane formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of alkane biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of alkane biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of alkane synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "dhl" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of alkane biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of alkane anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of alkane biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of alkane biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of alkane anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-11-05T21:54:11Z" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of alkane biosynthetic process" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of alkane biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of alkane synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of alkane biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of alkane formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of alkane formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of alkane formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901578" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of alkane anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of alkane biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of alkane synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of alkane anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of alkane formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of alkane synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of alkane anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447)) + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) SubClassOf [negative regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031327) + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) SubClassOf [regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901577) + +- [negative regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901578) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447) + + + +### negative regulation of amide metabolic process `http://purl.obolibrary.org/obo/GO_0034249` +#### Removed +- [negative regulation of amide metabolic process](http://purl.obolibrary.org/obo/GO_0034249) SubClassOf [negative regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051172) + +#### Added +- [negative regulation of amide metabolic process](http://purl.obolibrary.org/obo/GO_0034249) SubClassOf [negative regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009892) + + +### negative regulation of amine metabolic process `http://purl.obolibrary.org/obo/GO_0033239` +#### Removed +- [negative regulation of amine metabolic process](http://purl.obolibrary.org/obo/GO_0033239) SubClassOf [negative regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051172) + +#### Added +- [negative regulation of amine metabolic process](http://purl.obolibrary.org/obo/GO_0033239) SubClassOf [negative regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009892) + + +### negative regulation of amino acid biosynthetic process `http://purl.obolibrary.org/obo/GO_2000283` +#### Removed +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) SubClassOf [negative regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031327) + +#### Added +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) SubClassOf [negative regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009890) + + +### negative regulation of amino acid transport `http://purl.obolibrary.org/obo/GO_0051956` +#### Removed +- [negative regulation of amino acid transport](http://purl.obolibrary.org/obo/GO_0051956) SubClassOf [negative regulation of organic acid transport](http://purl.obolibrary.org/obo/GO_0032891) + + + +### negative regulation of apolipoprotein binding `http://purl.obolibrary.org/obo/GO_2000657` +#### Removed +- [negative regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000657) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "vk" + +- [negative regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000657) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000657" + +- [negative regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000657) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000657) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein binding." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:BHF" + +- [negative regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000657) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of apolipoprotein binding" + +- [negative regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000657) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-05-02T05:33:44Z" + +- Class: [negative regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000657) + +- [negative regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000657) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185)) + +- [negative regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000657) SubClassOf [regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000656) + +- [negative regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000657) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185) + +- [negative regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000657) SubClassOf [negative regulation of protein binding](http://purl.obolibrary.org/obo/GO_0032091) + + + +### negative regulation of calcium ion transmembrane transport `http://purl.obolibrary.org/obo/GO_1903170` +#### Removed +- [negative regulation of calcium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903170) SubClassOf [negative regulation of cation transmembrane transport](http://purl.obolibrary.org/obo/GO_1904063) + +#### Added +- [negative regulation of calcium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903170) SubClassOf [negative regulation of transmembrane transport](http://purl.obolibrary.org/obo/GO_0034763) + + +### negative regulation of calcium ion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_1901020` +#### Removed +- [negative regulation of calcium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901020) SubClassOf [negative regulation of ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0032413) + +#### Added +- [negative regulation of calcium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901020) SubClassOf [negative regulation of transporter activity](http://purl.obolibrary.org/obo/GO_0032410) + + +### negative regulation of calcium ion transport `http://purl.obolibrary.org/obo/GO_0051926` +#### Removed +- [negative regulation of calcium ion transport](http://purl.obolibrary.org/obo/GO_0051926) SubClassOf [negative regulation of monoatomic ion transport](http://purl.obolibrary.org/obo/GO_0043271) + +#### Added +- [negative regulation of calcium ion transport](http://purl.obolibrary.org/obo/GO_0051926) SubClassOf [negative regulation of transport](http://purl.obolibrary.org/obo/GO_0051051) + + +### negative regulation of cation channel activity `http://purl.obolibrary.org/obo/GO_2001258` +#### Removed +- [negative regulation of cation channel activity](http://purl.obolibrary.org/obo/GO_2001258) SubClassOf [negative regulation of ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0032413) + +#### Added +- [negative regulation of cation channel activity](http://purl.obolibrary.org/obo/GO_2001258) SubClassOf [negative regulation of transporter activity](http://purl.obolibrary.org/obo/GO_0032410) + + +### negative regulation of cation transmembrane transport `http://purl.obolibrary.org/obo/GO_1904063` +#### Removed +- [negative regulation of cation transmembrane transport](http://purl.obolibrary.org/obo/GO_1904063) SubClassOf [negative regulation of monoatomic ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0034766) + +#### Added +- [negative regulation of cation transmembrane transport](http://purl.obolibrary.org/obo/GO_1904063) SubClassOf [negative regulation of transmembrane transport](http://purl.obolibrary.org/obo/GO_0034763) + + +### negative regulation of cellular amino acid metabolic process `http://purl.obolibrary.org/obo/GO_0045763` + +#### Added +- [negative regulation of cellular amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0045763) SubClassOf [negative regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051172) + + +### negative regulation of cellular carbohydrate metabolic process `http://purl.obolibrary.org/obo/GO_0010677` +#### Removed +- [negative regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010677) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [negative regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010677) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0010677" + +- [negative regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010677) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010677) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of cellular carbohydrate metabolic process" + +- Class: [negative regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010677) + +- [negative regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010677) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262)) + +- [negative regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010677) SubClassOf [regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010675) + +- [negative regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010677) SubClassOf [negative regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031324) + +- [negative regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010677) SubClassOf [negative regulation of carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0045912) + +- [negative regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010677) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262) + + + +### negative regulation of cellular macromolecule biosynthetic process `http://purl.obolibrary.org/obo/GO_2000113` +#### Removed +- [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tb" + +- [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-09-15T08:55:48Z" + +- [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of cellular macromolecule formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of cellular macromolecule biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents, or reduces the frequency, rate or extent of cellular macromolecule biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of cellular macromolecule biosynthetic process" + +- [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000113" + +- [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of cellular biopolymer biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of cellular macromolecule synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of cellular macromolecule anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) + +- [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645)) + +- [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) SubClassOf [negative regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031327) + +- [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) SubClassOf [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) + +- [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) + +- [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) SubClassOf [negative regulation of macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0010558) + + + +### negative regulation of cellular response to alcohol `http://purl.obolibrary.org/obo/GO_1905958` +#### Removed +- [negative regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905958) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:26434723" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + +- [negative regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905958) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of cellular response to alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905958) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of cellular response to alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905958) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of cellular response to alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905958) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "hbye" + +- [negative regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905958) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1905958" + +- [negative regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905958) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2017-02-22T12:03:08Z" + +- [negative regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905958) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of cellular response to alcohol" + +- [negative regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905958) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905958) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of cellular response to alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [negative regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905958) + +- [negative regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905958) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306)) + +- [negative regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905958) SubClassOf [negative regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901420) + +- [negative regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905958) SubClassOf [negative regulation of cellular process](http://purl.obolibrary.org/obo/GO_0048523) + +- [negative regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905958) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306) + +- [negative regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905958) SubClassOf [regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905957) + + + +### negative regulation of cellular response to oxidative stress `http://purl.obolibrary.org/obo/GO_1900408` +#### Removed +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of cellular response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of cellular response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "down-regulation of adaptive response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of cellular response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "down regulation of adaptive response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of cellular response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of adaptive response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-04-20T03:31:05Z" + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of cellular response to oxidative stress" + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1900408" + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "downregulation of adaptive response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "negative regulation of adaptive response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599)) + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) SubClassOf [negative regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902883) + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) SubClassOf [regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900407) + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599) + +- [negative regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900408) SubClassOf [negative regulation of cellular process](http://purl.obolibrary.org/obo/GO_0048523) + + + +### negative regulation of dopamine metabolic process `http://purl.obolibrary.org/obo/GO_0045963` +#### Removed +- [negative regulation of dopamine metabolic process](http://purl.obolibrary.org/obo/GO_0045963) SubClassOf [negative regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051172) + +#### Added +- [negative regulation of dopamine metabolic process](http://purl.obolibrary.org/obo/GO_0045963) SubClassOf [negative regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009892) + + +### negative regulation of ecdysteroid metabolic process `http://purl.obolibrary.org/obo/GO_0045965` +#### Removed +- [negative regulation of ecdysteroid metabolic process](http://purl.obolibrary.org/obo/GO_0045965) SubClassOf [negative regulation of steroid metabolic process](http://purl.obolibrary.org/obo/GO_0045939) + + + +### negative regulation of epinephrine secretion `http://purl.obolibrary.org/obo/GO_0032811` +#### Removed +- [negative regulation of epinephrine secretion](http://purl.obolibrary.org/obo/GO_0032811) SubClassOf [negative regulation of catecholamine secretion](http://purl.obolibrary.org/obo/GO_0033604) + +#### Added +- [negative regulation of epinephrine secretion](http://purl.obolibrary.org/obo/GO_0032811) SubClassOf [negative regulation of secretion](http://purl.obolibrary.org/obo/GO_0051048) + + +### negative regulation of estrogen secretion `http://purl.obolibrary.org/obo/GO_2000862` +#### Removed +- [negative regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000862) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000862" + +- [negative regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000862) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "negative regulation of oestrogen secretion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [negative regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000862) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "bf" + +- [negative regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000862) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of estrogen secretion" + +- [negative regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000862) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000862) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-07-26T08:48:28Z" + +- [negative regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000862) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of estrogen secretion." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:sl" + +- Class: [negative regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000862) + +- [negative regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000862) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [estrogen secretion](http://purl.obolibrary.org/obo/GO_0035937)) + +- [negative regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000862) SubClassOf [negative regulation of steroid hormone secretion](http://purl.obolibrary.org/obo/GO_2000832) + +- [negative regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000862) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [estrogen secretion](http://purl.obolibrary.org/obo/GO_0035937) + +- [negative regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000862) SubClassOf [regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000861) + + + +### negative regulation of fatty acid biosynthetic process `http://purl.obolibrary.org/obo/GO_0045717` +#### Removed +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of fatty acid anabolism" + +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of fatty acid biosynthesis" + +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of fatty acid biosynthetic process" + +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of fatty acid formation" + +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of fatty acid synthesis" + +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of fatty acid biosynthetic process" + +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0045717" + +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of fatty acid biosynthetic process" + +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of fatty acid biosynthetic process" + +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of fatty acid biosynthetic process" + +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) + +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633)) + +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) + +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) SubClassOf [negative regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045922) + +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) SubClassOf [negative regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031327) + +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) SubClassOf [negative regulation of lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051055) + +- [negative regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045717) SubClassOf [regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042304) + + + +### negative regulation of fatty acid metabolic process `http://purl.obolibrary.org/obo/GO_0045922` +#### Removed +- [negative regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045922) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045922) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of fatty acid metabolic process" + +- [negative regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045922) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [negative regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045922) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of fatty acid metabolism" + +- [negative regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045922) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of fatty acid metabolic process" + +- [negative regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045922) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0045922" + +- [negative regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045922) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of fatty acid metabolic process" + +- [negative regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045922) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of fatty acid metabolic process" + +- [negative regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045922) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of fatty acid metabolic process" + +- Class: [negative regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045922) + +- [negative regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045922) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631)) + +- [negative regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045922) SubClassOf [negative regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031324) + +- [negative regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045922) SubClassOf [negative regulation of lipid metabolic process](http://purl.obolibrary.org/obo/GO_0045833) + +- [negative regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045922) SubClassOf [negative regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062014) + +- [negative regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045922) SubClassOf [regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0019217) + +- [negative regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045922) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631) + + + +### negative regulation of fatty acid transport `http://purl.obolibrary.org/obo/GO_2000192` +#### Removed +- [negative regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000192) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000192) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-10-18T10:37:15Z" + +- [negative regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000192) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000192" + +- [negative regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000192) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:BHF" + +- [negative regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000192) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "rl" + +- [negative regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000192) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of fatty acid transport" + +- Class: [negative regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000192) + +- [negative regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000192) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908)) + +- [negative regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000192) SubClassOf [regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000191) + +- [negative regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000192) SubClassOf [negative regulation of lipid transport](http://purl.obolibrary.org/obo/GO_0032369) + +- [negative regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000192) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908) + + + +### negative regulation of fermentation `http://purl.obolibrary.org/obo/GO_1901003` +#### Removed +- [negative regulation of fermentation](http://purl.obolibrary.org/obo/GO_1901003) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of fermentation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of fermentation](http://purl.obolibrary.org/obo/GO_1901003) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of fermentation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of fermentation](http://purl.obolibrary.org/obo/GO_1901003) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of fermentation](http://purl.obolibrary.org/obo/GO_1901003) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of fermentation." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of fermentation](http://purl.obolibrary.org/obo/GO_1901003) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of fermentation" + +- [negative regulation of fermentation](http://purl.obolibrary.org/obo/GO_1901003) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of fermentation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of fermentation](http://purl.obolibrary.org/obo/GO_1901003) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of fermentation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of fermentation](http://purl.obolibrary.org/obo/GO_1901003) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-06-15T08:21:31Z" + +- [negative regulation of fermentation](http://purl.obolibrary.org/obo/GO_1901003) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901003" + +- [negative regulation of fermentation](http://purl.obolibrary.org/obo/GO_1901003) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "al" + +- Class: [negative regulation of fermentation](http://purl.obolibrary.org/obo/GO_1901003) + +- [negative regulation of fermentation](http://purl.obolibrary.org/obo/GO_1901003) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [fermentation](http://purl.obolibrary.org/obo/GO_0006113)) + +- [negative regulation of fermentation](http://purl.obolibrary.org/obo/GO_1901003) SubClassOf [regulation of fermentation](http://purl.obolibrary.org/obo/GO_0043465) + +- [negative regulation of fermentation](http://purl.obolibrary.org/obo/GO_1901003) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [fermentation](http://purl.obolibrary.org/obo/GO_0006113) + +- [negative regulation of fermentation](http://purl.obolibrary.org/obo/GO_1901003) SubClassOf [negative regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031324) + + + +### negative regulation of glucocorticoid catabolic process `http://purl.obolibrary.org/obo/GO_0031950` +#### Removed +- [negative regulation of glucocorticoid catabolic process](http://purl.obolibrary.org/obo/GO_0031950) SubClassOf [negative regulation of lipid catabolic process](http://purl.obolibrary.org/obo/GO_0050995) + + + +### negative regulation of gluconeogenesis `http://purl.obolibrary.org/obo/GO_0045721` +#### Removed +- [negative regulation of gluconeogenesis](http://purl.obolibrary.org/obo/GO_0045721) SubClassOf [negative regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010677) + +- [negative regulation of gluconeogenesis](http://purl.obolibrary.org/obo/GO_0045721) SubClassOf [negative regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062014) + +#### Added +- [negative regulation of gluconeogenesis](http://purl.obolibrary.org/obo/GO_0045721) SubClassOf [negative regulation of carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0045912) + + +### negative regulation of glycogen biosynthetic process `http://purl.obolibrary.org/obo/GO_0045719` +#### Removed +- [negative regulation of glycogen biosynthetic process](http://purl.obolibrary.org/obo/GO_0045719) SubClassOf [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) + +#### Added +- [negative regulation of glycogen biosynthetic process](http://purl.obolibrary.org/obo/GO_0045719) SubClassOf [negative regulation of macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0010558) + + +### negative regulation of glycogen metabolic process `http://purl.obolibrary.org/obo/GO_0070874` +#### Removed +- [negative regulation of glycogen metabolic process](http://purl.obolibrary.org/obo/GO_0070874) SubClassOf [negative regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010677) + +#### Added +- [negative regulation of glycogen metabolic process](http://purl.obolibrary.org/obo/GO_0070874) SubClassOf [negative regulation of carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0045912) + +- [negative regulation of glycogen metabolic process](http://purl.obolibrary.org/obo/GO_0070874) SubClassOf [negative regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031324) + + +### negative regulation of glycoprotein biosynthetic process `http://purl.obolibrary.org/obo/GO_0010561` +#### Removed +- [negative regulation of glycoprotein biosynthetic process](http://purl.obolibrary.org/obo/GO_0010561) SubClassOf [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) + +#### Added +- [negative regulation of glycoprotein biosynthetic process](http://purl.obolibrary.org/obo/GO_0010561) SubClassOf [negative regulation of macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0010558) + + +### negative regulation of glycoprotein metabolic process `http://purl.obolibrary.org/obo/GO_1903019` +#### Removed +- [negative regulation of glycoprotein metabolic process](http://purl.obolibrary.org/obo/GO_1903019) SubClassOf [negative regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031324) + +- [negative regulation of glycoprotein metabolic process](http://purl.obolibrary.org/obo/GO_1903019) SubClassOf [negative regulation of protein metabolic process](http://purl.obolibrary.org/obo/GO_0051248) + +#### Added +- [negative regulation of glycoprotein metabolic process](http://purl.obolibrary.org/obo/GO_1903019) SubClassOf [negative regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009892) + + +### negative regulation of hyaluronan biosynthetic process `http://purl.obolibrary.org/obo/GO_1900126` +#### Removed +- [negative regulation of hyaluronan biosynthetic process](http://purl.obolibrary.org/obo/GO_1900126) SubClassOf [negative regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051172) + +- [negative regulation of hyaluronan biosynthetic process](http://purl.obolibrary.org/obo/GO_1900126) SubClassOf [negative regulation of macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0010558) + +#### Added +- [negative regulation of hyaluronan biosynthetic process](http://purl.obolibrary.org/obo/GO_1900126) SubClassOf [negative regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009890) + + +### negative regulation of inorganic anion transmembrane transport `http://purl.obolibrary.org/obo/GO_1903796` +#### Removed +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of inorganic anion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of transmembrane inorganic anion transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of inorganic anion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of inorganic anion transmembrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1903796" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of inorganic anion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of inorganic anion transmembrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of transmembrane inorganic anion transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of transmembrane inorganic anion transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of inorganic anion transmembrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2015-01-14T21:44:59Z" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of inorganic anion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of transmembrane inorganic anion transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of inorganic anion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of transmembrane inorganic anion transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of inorganic anion transmembrane transport" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "sl" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of inorganic anion transmembrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of inorganic anion transmembrane transport." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11336802" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + +- Class: [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661)) + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661) + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) SubClassOf [regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903795) + +- [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) SubClassOf [negative regulation of transmembrane transport](http://purl.obolibrary.org/obo/GO_0034763) + + + +### negative regulation of iron ion transmembrane transport `http://purl.obolibrary.org/obo/GO_0034760` +#### Removed +- [negative regulation of iron ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0034760) SubClassOf [negative regulation of cation transmembrane transport](http://purl.obolibrary.org/obo/GO_1904063) + +#### Added +- [negative regulation of iron ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0034760) SubClassOf [negative regulation of transmembrane transport](http://purl.obolibrary.org/obo/GO_0034763) + + +### negative regulation of iron ion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_1904255` +#### Removed +- [negative regulation of iron ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1904255) SubClassOf [negative regulation of ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0032413) + +#### Added +- [negative regulation of iron ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1904255) SubClassOf [negative regulation of transporter activity](http://purl.obolibrary.org/obo/GO_0032410) + + +### negative regulation of iron ion transport `http://purl.obolibrary.org/obo/GO_0034757` +#### Removed +- [negative regulation of iron ion transport](http://purl.obolibrary.org/obo/GO_0034757) SubClassOf [negative regulation of monoatomic ion transport](http://purl.obolibrary.org/obo/GO_0043271) + +#### Added +- [negative regulation of iron ion transport](http://purl.obolibrary.org/obo/GO_0034757) SubClassOf [negative regulation of transport](http://purl.obolibrary.org/obo/GO_0051051) + + +### negative regulation of isoprenoid metabolic process `http://purl.obolibrary.org/obo/GO_0045827` +#### Removed +- [negative regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045827) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045827) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of isoprenoid metabolic process" + +- [negative regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045827) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of isoprenoid metabolic process" + +- [negative regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045827) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of isoprenoid metabolic process" + +- [negative regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045827) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0045827" + +- [negative regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045827) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of isoprenoid metabolic process" + +- [negative regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045827) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of isoprenoid metabolic process" + +- [negative regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045827) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [negative regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045827) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of isoprenoid metabolism" + +- Class: [negative regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045827) + +- [negative regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045827) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720)) + +- [negative regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045827) SubClassOf [regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0019747) + +- [negative regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045827) SubClassOf [negative regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031324) + +- [negative regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045827) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) + +- [negative regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045827) SubClassOf [negative regulation of lipid metabolic process](http://purl.obolibrary.org/obo/GO_0045833) + + + +### negative regulation of juvenile hormone biosynthetic process `http://purl.obolibrary.org/obo/GO_0045968` +#### Removed +- [negative regulation of juvenile hormone biosynthetic process](http://purl.obolibrary.org/obo/GO_0045968) SubClassOf [negative regulation of lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051055) + + + +### negative regulation of juvenile hormone catabolic process `http://purl.obolibrary.org/obo/GO_0045970` +#### Removed +- [negative regulation of juvenile hormone catabolic process](http://purl.obolibrary.org/obo/GO_0045970) SubClassOf [negative regulation of lipid catabolic process](http://purl.obolibrary.org/obo/GO_0050995) + +- [negative regulation of juvenile hormone catabolic process](http://purl.obolibrary.org/obo/GO_0045970) SubClassOf [negative regulation of cellular catabolic process](http://purl.obolibrary.org/obo/GO_0031330) + +#### Added +- [negative regulation of juvenile hormone catabolic process](http://purl.obolibrary.org/obo/GO_0045970) SubClassOf [negative regulation of catabolic process](http://purl.obolibrary.org/obo/GO_0009895) + + +### negative regulation of juvenile hormone metabolic process `http://purl.obolibrary.org/obo/GO_0045928` +#### Removed +- [negative regulation of juvenile hormone metabolic process](http://purl.obolibrary.org/obo/GO_0045928) SubClassOf [negative regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045827) + + + +### negative regulation of juvenile hormone secretion `http://purl.obolibrary.org/obo/GO_0045972` +#### Removed +- [negative regulation of juvenile hormone secretion](http://purl.obolibrary.org/obo/GO_0045972) SubClassOf [negative regulation of lipid transport](http://purl.obolibrary.org/obo/GO_0032369) + + + +### negative regulation of lipoprotein metabolic process `http://purl.obolibrary.org/obo/GO_0050748` +#### Removed +- [negative regulation of lipoprotein metabolic process](http://purl.obolibrary.org/obo/GO_0050748) SubClassOf [negative regulation of protein metabolic process](http://purl.obolibrary.org/obo/GO_0051248) + + + +### negative regulation of lipoprotein transport `http://purl.obolibrary.org/obo/GO_0140076` +#### Removed +- [negative regulation of lipoprotein transport](http://purl.obolibrary.org/obo/GO_0140076) SubClassOf [negative regulation of protein transport](http://purl.obolibrary.org/obo/GO_0051224) + +#### Added +- [negative regulation of lipoprotein transport](http://purl.obolibrary.org/obo/GO_0140076) SubClassOf [negative regulation of transport](http://purl.obolibrary.org/obo/GO_0051051) + + +### negative regulation of nitric oxide biosynthetic process `http://purl.obolibrary.org/obo/GO_0045019` + +#### Added +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) SubClassOf [negative regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051172) + + +### negative regulation of nitric oxide metabolic process `http://purl.obolibrary.org/obo/GO_1904406` +#### Removed +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) SubClassOf [negative regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051172) + +#### Added +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) SubClassOf [negative regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009892) + + +### negative regulation of peptide hormone processing `http://purl.obolibrary.org/obo/GO_0060570` +#### Removed +- [negative regulation of peptide hormone processing](http://purl.obolibrary.org/obo/GO_0060570) SubClassOf [negative regulation of amide metabolic process](http://purl.obolibrary.org/obo/GO_0034249) + + + +### negative regulation of phagocytosis `http://purl.obolibrary.org/obo/GO_0050765` +#### Removed +- [negative regulation of phagocytosis](http://purl.obolibrary.org/obo/GO_0050765) SubClassOf [negative regulation of transport](http://purl.obolibrary.org/obo/GO_0051051) + +#### Added +- [negative regulation of phagocytosis](http://purl.obolibrary.org/obo/GO_0050765) SubClassOf [negative regulation of endocytosis](http://purl.obolibrary.org/obo/GO_0045806) + + +### negative regulation of phosphate metabolic process `http://purl.obolibrary.org/obo/GO_0045936` +#### Removed +- [negative regulation of phosphate metabolic process](http://purl.obolibrary.org/obo/GO_0045936) SubClassOf [negative regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010563) + +#### Added +- [negative regulation of phosphate metabolic process](http://purl.obolibrary.org/obo/GO_0045936) SubClassOf [negative regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009892) + + +### negative regulation of phosphate transmembrane transport `http://purl.obolibrary.org/obo/GO_2000186` +#### Removed +- [negative regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000186) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of phosphate membrane transport" + +- [negative regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000186) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-10-15T11:33:08Z" + +- [negative regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000186) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of phosphate transmembrane transport" + +- [negative regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000186) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000186" + +- [negative regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000186) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000186) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [negative regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000186) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "vw" + +- Class: [negative regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000186) + +- [negative regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000186) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435)) + +- [negative regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000186) SubClassOf [negative regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903796) + +- [negative regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000186) SubClassOf [regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000185) + +- [negative regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000186) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435) + + + +### negative regulation of phosphorus metabolic process `http://purl.obolibrary.org/obo/GO_0010563` +#### Removed +- [negative regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010563) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0010563" + +- [negative regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010563) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of phosphorus metabolic process" + +- [negative regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010563) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010563) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- Class: [negative regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010563) + +- [negative regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010563) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0006793)) + +- [negative regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010563) SubClassOf [negative regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031324) + +- [negative regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010563) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0006793) + +- [negative regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010563) SubClassOf [regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0051174) + + + +### negative regulation of progesterone biosynthetic process `http://purl.obolibrary.org/obo/GO_2000183` +#### Removed +- [negative regulation of progesterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000183) SubClassOf [negative regulation of steroid biosynthetic process](http://purl.obolibrary.org/obo/GO_0010894) + +- [negative regulation of progesterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000183) SubClassOf [negative regulation of hormone biosynthetic process](http://purl.obolibrary.org/obo/GO_0032353) + +- [negative regulation of progesterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000183) SubClassOf [negative regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062014) + +#### Added +- [negative regulation of progesterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000183) SubClassOf [negative regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009890) + + +### negative regulation of protein metabolic process `http://purl.obolibrary.org/obo/GO_0051248` +#### Removed +- [negative regulation of protein metabolic process](http://purl.obolibrary.org/obo/GO_0051248) SubClassOf [negative regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051172) + +- [negative regulation of protein metabolic process](http://purl.obolibrary.org/obo/GO_0051248) SubClassOf [negative regulation of macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0010605) + +#### Added +- [negative regulation of protein metabolic process](http://purl.obolibrary.org/obo/GO_0051248) SubClassOf [negative regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009892) + + +### negative regulation of protein modification process `http://purl.obolibrary.org/obo/GO_0031400` + +#### Added +- [negative regulation of protein modification process](http://purl.obolibrary.org/obo/GO_0031400) SubClassOf [negative regulation of macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0010605) + + +### negative regulation of proteoglycan biosynthetic process `http://purl.obolibrary.org/obo/GO_1902729` +#### Removed +- [negative regulation of proteoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_1902729) SubClassOf [negative regulation of glycoprotein biosynthetic process](http://purl.obolibrary.org/obo/GO_0010561) + +#### Added +- [negative regulation of proteoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_1902729) SubClassOf [negative regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009890) + + +### negative regulation of reactive oxygen species biosynthetic process `http://purl.obolibrary.org/obo/GO_1903427` +#### Removed +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "negative regulation of reactive oxygen species generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of reactive oxygen species formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of reactive oxygen species formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "down regulation of reactive oxygen species generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inhibition of ROS formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of reactive oxygen species biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "negative regulation of ROS generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of reactive oxygen species synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of reactive oxygen species biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "downregulation of reactive oxygen species generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of reactive oxygen species biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "downregulation of ROS generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1903427" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of reactive oxygen species formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of reactive oxygen species biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of reactive oxygen species formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of reactive oxygen species biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inhibition of ROS generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "down regulation of ROS formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of reactive oxygen species biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "negative regulation of ROS formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "bf" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of reactive oxygen species anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of reactive oxygen species biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "prevention of ROS generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24252804" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of reactive oxygen species synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of reactive oxygen species anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of reactive oxygen species anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of reactive oxygen species biosynthetic process" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "downregulation of ROS formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of reactive oxygen species biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-09-11T10:01:56Z" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "down-regulation of ROS generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of reactive oxygen species anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:bf" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24252804" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:PARL" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of reactive oxygen species anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of reactive oxygen species synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of reactive oxygen species biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of reactive oxygen species synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of reactive oxygen species synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "down regulation of ROS generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "down-regulation of reactive oxygen species generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of reactive oxygen species formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inhibition of reactive oxygen species generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "down-regulation of ROS formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409)) + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) SubClassOf [negative regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000378) + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) SubClassOf [negative regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009890) + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) + +- [negative regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903427) SubClassOf [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) + + + +### negative regulation of reactive oxygen species metabolic process `http://purl.obolibrary.org/obo/GO_2000378` +#### Removed +- [negative regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000378) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000378) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000378" + +- [negative regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000378) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of reactive oxygen species metabolic process" + +- [negative regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000378) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-02-11T02:06:49Z" + +- [negative regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000378) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [negative regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000378) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of ROS metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [negative regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000378) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- [negative regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000378) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of reactive oxygen species metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- Class: [negative regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000378) + +- [negative regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000378) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593)) + +- [negative regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000378) SubClassOf [regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000377) + +- [negative regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000378) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593) + +- [negative regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000378) SubClassOf [negative regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031324) + + + +### negative regulation of response to acetate `http://purl.obolibrary.org/obo/GO_1901458` +#### Removed +- [negative regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901458) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of response to acetate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901458) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of response to acetate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901458) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901458" + +- [negative regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901458) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [negative regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901458) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of response to acetate" + +- [negative regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901458) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of response to acetate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901458) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [negative regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901458) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of response to acetate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901458) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-02T14:26:15Z" + +- [negative regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901458) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [negative regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901458) + +- [negative regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901458) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [response to acetate](http://purl.obolibrary.org/obo/GO_0010034)) + +- [negative regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901458) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [response to acetate](http://purl.obolibrary.org/obo/GO_0010034) + +- [negative regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901458) SubClassOf [negative regulation of response to stimulus](http://purl.obolibrary.org/obo/GO_0048585) + +- [negative regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901458) SubClassOf [regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901457) + + + +### negative regulation of response to alcohol `http://purl.obolibrary.org/obo/GO_1901420` +#### Removed +- [negative regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901420) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [negative regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901420) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of response to alcohol" + +- [negative regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901420) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of response to alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901420) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [negative regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901420) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of response to alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901420) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901420) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901420" + +- [negative regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901420) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of response to alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901420) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of response to alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901420) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-01T16:53:25Z" + +- Class: [negative regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901420) + +- [negative regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901420) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305)) + +- [negative regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901420) SubClassOf [regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901419) + +- [negative regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901420) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) + +- [negative regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901420) SubClassOf [negative regulation of response to stimulus](http://purl.obolibrary.org/obo/GO_0048585) + + + +### negative regulation of response to formic acid `http://purl.obolibrary.org/obo/GO_1901461` +#### Removed +- [negative regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901461) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of response to formic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [negative regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901461) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901461" + +- [negative regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901461) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of response to formic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901461) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of response to formic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901461) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of response to formic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901461) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of response to formic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901461) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of response to formic acid" + +- [negative regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901461) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [negative regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901461) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901461) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-02T14:29:02Z" + +- Class: [negative regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901461) + +- [negative regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901461) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [response to formic acid](http://purl.obolibrary.org/obo/GO_1901425)) + +- [negative regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901461) SubClassOf [negative regulation of response to stimulus](http://purl.obolibrary.org/obo/GO_0048585) + +- [negative regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901461) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [response to formic acid](http://purl.obolibrary.org/obo/GO_1901425) + +- [negative regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901461) SubClassOf [regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901460) + + + +### negative regulation of response to oxidative stress `http://purl.obolibrary.org/obo/GO_1902883` +#### Removed +- [negative regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902883) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of response to oxidative stress" + +- [negative regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902883) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902883" + +- [negative regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902883) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902883) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16899554" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:kmv" + +- [negative regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902883) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902883) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902883) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902883) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902883) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "kmv" + +- [negative regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902883) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-04-03T20:30:20Z" + +- Class: [negative regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902883) + +- [negative regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902883) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [response to oxidative stress](http://purl.obolibrary.org/obo/GO_0006979)) + +- [negative regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902883) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [response to oxidative stress](http://purl.obolibrary.org/obo/GO_0006979) + +- [negative regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902883) SubClassOf [negative regulation of response to stimulus](http://purl.obolibrary.org/obo/GO_0048585) + +- [negative regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902883) SubClassOf [regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902882) + + + +### negative regulation of response to reactive oxygen species `http://purl.obolibrary.org/obo/GO_1901032` +#### Removed +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of response to ROI" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of response to reactive oxidative species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of response to ROS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of response to ROS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of response to reactive oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:kmv" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of response to AOS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-06-20T07:47:28Z" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of response to active oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of response to reactive oxidative species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901032" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of response to reactive oxidative species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of response to reactive oxidative species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of response to reactive oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of response to active oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of response to ROS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of response to reactive oxygen intermediate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of response to ROI" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of response to AOS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of response to ROS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of response to reactive oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of response to reactive oxygen intermediate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of response to reactive oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of response to active oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of response to AOS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of response to ROI" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of response to reactive oxidative species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of response to reactive oxygen intermediate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "kmv" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of response to AOS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of response to ROI" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of response to reactive oxygen intermediate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of response to reactive oxygen species" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of response to active oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of response to reactive oxygen intermediate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of response to ROI" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of response to active oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of response to AOS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of response to ROS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302)) + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) SubClassOf [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) SubClassOf [negative regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902883) + +- [negative regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901032) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) + + + +### negative regulation of secondary metabolite biosynthetic process `http://purl.obolibrary.org/obo/GO_1900377` +#### Removed +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of secondary metabolite biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of secondary metabolite biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:di" + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1900377" + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-04-17T01:55:32Z" + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of secondary metabolite biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of secondary metabolite biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of secondary metabolite biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of secondary metabolite biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of secondary metabolite biosynthetic process" + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "di" + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of secondary metabolite biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of secondary metabolite biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of secondary metabolite biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550)) + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550) + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) SubClassOf [regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900376) + +- [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) SubClassOf [negative regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009890) + + + +### negative regulation of sodium ion transmembrane transport `http://purl.obolibrary.org/obo/GO_1902306` +#### Removed +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of sodium ion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_cardiac_conduct_nov11" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:rl" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:BHF" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18591664" + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of sodium ion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of sodium ion transmembrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of sodium ion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of sodium ion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of sodium ion transmembrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of sodium ion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2013-07-18T13:34:01Z" + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of sodium ion transmembrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "rl" + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902306" + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of sodium ion transmembrane transport" + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of sodium ion transmembrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725)) + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) SubClassOf [regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902305) + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725) + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) SubClassOf [negative regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010766) + +- [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) SubClassOf [negative regulation of cation transmembrane transport](http://purl.obolibrary.org/obo/GO_1904063) + + + +### negative regulation of sodium ion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_2000650` +#### Removed +- [negative regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000650) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000650" + +- [negative regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000650) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [negative regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000650) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of sodium ion transmembrane transporter activity" + +- [negative regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000650) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-04-28T08:42:57Z" + +- [negative regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000650) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000650) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "yaf" + +- [negative regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000650) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of sodium transporter activity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- Class: [negative regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000650) + +- [negative regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000650) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081)) + +- [negative regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000650) SubClassOf [negative regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902306) + +- [negative regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000650) SubClassOf [negative regulation of ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0032413) + +- [negative regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000650) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081) + +- [negative regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000650) SubClassOf [regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000649) + + + +### negative regulation of sodium ion transport `http://purl.obolibrary.org/obo/GO_0010766` +#### Removed +- [negative regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010766) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010766) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of sodium ion transport" + +- [negative regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010766) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [negative regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010766) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0010766" + +- Class: [negative regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010766) + +- [negative regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010766) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814)) + +- [negative regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010766) SubClassOf [regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0002028) + +- [negative regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010766) SubClassOf [negative regulation of monoatomic ion transport](http://purl.obolibrary.org/obo/GO_0043271) + +- [negative regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010766) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) + + + +### negative regulation of sphingolipid biosynthetic process `http://purl.obolibrary.org/obo/GO_0090155` +#### Removed +- [negative regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090155) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0090157" + +- [negative regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090155) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis" + +- [negative regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090155) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ascb_2009" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [negative regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090155) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0090155" + +- [negative regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090155) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2009-12-08T03:33:39Z" + +- [negative regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090155) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090155) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of sphingolipid biosynthetic process" + +- [negative regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090155) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tb" + +- Class: [negative regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090155) + +- [negative regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090155) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148)) + +- [negative regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090155) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) + +- [negative regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090155) SubClassOf [negative regulation of lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051055) + +- [negative regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090155) SubClassOf [negative regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031327) + +- [negative regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090155) SubClassOf [negative regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051172) + +- [negative regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090155) SubClassOf [regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090153) + + + +### negative regulation of sulfur metabolic process `http://purl.obolibrary.org/obo/GO_0051175` +#### Removed +- [negative regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051175) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of sulfur metabolic process" + +- [negative regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051175) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of sulphur metabolic process" + +- [negative regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051175) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of sulfur metabolism" + +- [negative regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051175) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0051175" + +- [negative regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051175) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of sulphur metabolism" + +- [negative regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051175) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of sulfur metabolic process" + +- [negative regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051175) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of sulfur metabolic process" + +- [negative regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051175) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051175) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of sulfur metabolic process" + +- [negative regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051175) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of sulfur metabolic process" + +- [negative regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051175) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- Class: [negative regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051175) + +- [negative regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051175) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790)) + +- [negative regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051175) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) + +- [negative regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051175) SubClassOf [regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0042762) + +- [negative regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051175) SubClassOf [negative regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031324) + + + +### negative regulation of superoxide anion generation `http://purl.obolibrary.org/obo/GO_0032929` +#### Removed +- [negative regulation of superoxide anion generation](http://purl.obolibrary.org/obo/GO_0032929) SubClassOf [negative regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000378) + +#### Added +- [negative regulation of superoxide anion generation](http://purl.obolibrary.org/obo/GO_0032929) SubClassOf [negative regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009892) + + +### negative regulation of testosterone biosynthetic process `http://purl.obolibrary.org/obo/GO_2000225` +#### Removed +- [negative regulation of testosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000225) SubClassOf [negative regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062014) + +- [negative regulation of testosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000225) SubClassOf [negative regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031327) + +- [negative regulation of testosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000225) SubClassOf [negative regulation of steroid biosynthetic process](http://purl.obolibrary.org/obo/GO_0010894) + +#### Added +- [negative regulation of testosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000225) SubClassOf [negative regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009890) + + +### negative regulation of testosterone secretion `http://purl.obolibrary.org/obo/GO_2000844` +#### Removed +- [negative regulation of testosterone secretion](http://purl.obolibrary.org/obo/GO_2000844) SubClassOf [negative regulation of lipid transport](http://purl.obolibrary.org/obo/GO_0032369) + + + +### negative regulation of tetrapyrrole biosynthetic process `http://purl.obolibrary.org/obo/GO_1901464` +#### Removed +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of tetrapyrrole biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-02T14:35:26Z" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of tetrapyrrole biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of tetrapyrrole formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901464" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of tetrapyrrole synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of tetrapyrrole formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of tetrapyrrole anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of tetrapyrrole anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of tetrapyrrole biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of tetrapyrrole anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of tetrapyrrole biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of tetrapyrrole synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of tetrapyrrole biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of tetrapyrrole synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of tetrapyrrole biosynthetic process" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of tetrapyrrole formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of tetrapyrrole biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of tetrapyrrole anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of tetrapyrrole biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of tetrapyrrole biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of tetrapyrrole synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of tetrapyrrole formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of tetrapyrrole synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of tetrapyrrole anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of tetrapyrrole formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of tetrapyrrole biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014)) + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) SubClassOf [negative regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031327) + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) SubClassOf [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) + +- [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) SubClassOf [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) + + + +### negative regulation of tetrapyrrole biosynthetic process from glutamate `http://purl.obolibrary.org/obo/GO_1901411` +#### Removed +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901411" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of tetrapyrrole synthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of tetrapyrrole anabolism from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of tetrapyrrole synthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of tetrapyrrole synthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of tetrapyrrole anabolism from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of tetrapyrrole biosynthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of tetrapyrrole formation from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of tetrapyrrole biosynthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of tetrapyrrole synthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of tetrapyrrole biosynthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-01T16:22:03Z" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of tetrapyrrole formation from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of tetrapyrrole biosynthetic process from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of tetrapyrrole biosynthetic process from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of tetrapyrrole formation from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of tetrapyrrole biosynthetic process from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of tetrapyrrole synthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of tetrapyrrole anabolism from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of tetrapyrrole biosynthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of tetrapyrrole formation from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of tetrapyrrole biosynthetic process from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of tetrapyrrole biosynthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of tetrapyrrole biosynthetic process from glutamate" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of tetrapyrrole formation from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of tetrapyrrole anabolism from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of tetrapyrrole anabolism from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526)) + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526) + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) SubClassOf [negative regulation of glutamate metabolic process](http://purl.obolibrary.org/obo/GO_2000212) + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) SubClassOf [negative regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901464) + +- [negative regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901411) SubClassOf [regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901410) + + + +### negative regulation of tetrapyrrole catabolic process `http://purl.obolibrary.org/obo/GO_1901405` +#### Removed +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of tetrapyrrole catabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of tetrapyrrole breakdown" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of tetrapyrrole breakdown" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of tetrapyrrole breakdown" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of tetrapyrrole breakdown" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of tetrapyrrole catabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of tetrapyrrole catabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of tetrapyrrole breakdown" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of tetrapyrrole catabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of tetrapyrrole catabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of tetrapyrrole degradation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of tetrapyrrole degradation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of tetrapyrrole degradation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of tetrapyrrole degradation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of tetrapyrrole catabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of tetrapyrrole catabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of tetrapyrrole catabolic process" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-01T14:39:22Z" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of tetrapyrrole catabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of tetrapyrrole catabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901405" + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of tetrapyrrole degradation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015)) + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) SubClassOf [regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901404) + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) SubClassOf [negative regulation of cellular catabolic process](http://purl.obolibrary.org/obo/GO_0031330) + +- [negative regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901405) SubClassOf [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) + + + +### negative regulation of tetrapyrrole metabolic process `http://purl.obolibrary.org/obo/GO_1901402` +#### Removed +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of tetrapyrrole metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of tetrapyrrole metabolic process" + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of tetrapyrrole metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of tetrapyrrole metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of tetrapyrrole metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of tetrapyrrole metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901402" + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-01T14:35:11Z" + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of tetrapyrrole metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of tetrapyrrole metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of tetrapyrrole metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inhibition of tetrapyrrole metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- Class: [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013)) + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) SubClassOf [negative regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031324) + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) SubClassOf [negative regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051172) + +- [negative regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901402) SubClassOf [regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901401) + + + +### negative regulation of translation `http://purl.obolibrary.org/obo/GO_0017148` +#### Removed +- [negative regulation of translation](http://purl.obolibrary.org/obo/GO_0017148) SubClassOf [negative regulation of amide metabolic process](http://purl.obolibrary.org/obo/GO_0034249) + +- [negative regulation of translation](http://purl.obolibrary.org/obo/GO_0017148) SubClassOf [negative regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000113) + +#### Added +- [negative regulation of translation](http://purl.obolibrary.org/obo/GO_0017148) SubClassOf [negative regulation of macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0010558) + + +### negative regulation of translation in response to oxidative stress `http://purl.obolibrary.org/obo/GO_0032938` +#### Removed +- [negative regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032938) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0032938" + +- [negative regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032938) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of translation in response to oxidative stress" + +- [negative regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032938) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032938) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- Class: [negative regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032938) + +- [negative regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032938) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599)) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [translational initiation](http://purl.obolibrary.org/obo/GO_0006413)) + +- [negative regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032938) SubClassOf [negative regulation of translational initiation in response to stress](http://purl.obolibrary.org/obo/GO_0032057) + +- [negative regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032938) SubClassOf [regulation of translational initiation in response to stress](http://purl.obolibrary.org/obo/GO_0043558) + +- [negative regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032938) SubClassOf [regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0043556) + + + +### negative regulation of translation in response to stress `http://purl.obolibrary.org/obo/GO_0032055` +#### Removed +- [negative regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032055) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of translation in response to stress" + +- [negative regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032055) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [negative regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032055) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0032055" + +- [negative regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032055) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032055) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of translation in response to stress" + +- [negative regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032055) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of translation in response to stress" + +- [negative regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032055) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of translation in response to stress" + +- [negative regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032055) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of translation in response to stress" + +- Class: [negative regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032055) + +- [negative regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032055) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [cellular response to stress](http://purl.obolibrary.org/obo/GO_0033554)) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [translation](http://purl.obolibrary.org/obo/GO_0006412)) + +- [negative regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032055) SubClassOf [regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0043555) + +- [negative regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032055) SubClassOf [negative regulation of translation](http://purl.obolibrary.org/obo/GO_0017148) + + + +### negative regulation of translational initiation `http://purl.obolibrary.org/obo/GO_0045947` + +#### Added +- [negative regulation of translational initiation](http://purl.obolibrary.org/obo/GO_0045947) SubClassOf [negative regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031324) + + +### negative regulation of voltage-gated calcium channel activity `http://purl.obolibrary.org/obo/GO_1901386` +#### Removed +- [negative regulation of voltage-gated calcium channel activity](http://purl.obolibrary.org/obo/GO_1901386) SubClassOf [negative regulation of cation channel activity](http://purl.obolibrary.org/obo/GO_2001258) + + + +### negatively regulated by `http://purl.obolibrary.org/obo/RO_0002335` +#### Removed +- [negatively regulated by](http://purl.obolibrary.org/obo/RO_0002335) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [negatively regulated by](http://purl.obolibrary.org/obo/RO_0002335) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### negatively regulates `http://purl.obolibrary.org/obo/RO_0002212` +#### Removed +- [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall"@en + +#### Added +- [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### neural cell `http://purl.obolibrary.org/obo/CL_0002319` +#### Removed +- [neural cell](http://purl.obolibrary.org/obo/CL_0002319) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### neuroblast (sensu Vertebrata) `http://purl.obolibrary.org/obo/CL_0000031` +#### Removed +- [neuroblast (sensu Vertebrata)](http://purl.obolibrary.org/obo/CL_0000031) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000337" + + + +### neuroendocrine cell `http://purl.obolibrary.org/obo/CL_0000165` +#### Removed +- [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000381" + + + +### neuroendocrine cell of epithelium of crypt of Lieberkuhn `http://purl.obolibrary.org/obo/CL_4033002` +#### Removed +- [neuroendocrine cell of epithelium of crypt of Lieberkuhn](http://purl.obolibrary.org/obo/CL_4033002) SubClassOf [intestinal epithelial cell](http://purl.obolibrary.org/obo/CL_0002563) + +#### Added +- [neuroendocrine cell of epithelium of crypt of Lieberkuhn](http://purl.obolibrary.org/obo/CL_4033002) SubClassOf [intestinal enteroendocrine cell](http://purl.obolibrary.org/obo/CL_1001516) + + +### neuromast supporting cell `http://purl.obolibrary.org/obo/CL_0000852` +#### Removed +- [neuromast supporting cell](http://purl.obolibrary.org/obo/CL_0000852) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### neuron `http://purl.obolibrary.org/obo/CL_0000540` +#### Removed +- [neuron](http://purl.obolibrary.org/obo/CL_0000540) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### neurotoxin `http://purl.obolibrary.org/obo/CHEBI_50910` +#### Removed +- [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "agente neurotoxico" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neurotoxin" + +- [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) [label](http://www.w3.org/2000/01/rdf-schema#label) "neurotoxin" + +- [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "neurotoxic agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A poison that interferes with the functions of the nervous system." + +- [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "neurotoxic agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "neurotoxicant" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nerve poisons" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nerve poison" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50910" + +- [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:50911" + +- [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "neurotoxins" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) + +- [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) SubClassOf [aetiopathogenetic role](http://purl.obolibrary.org/obo/CHEBI_52209) + +- [neurotoxin](http://purl.obolibrary.org/obo/CHEBI_50910) SubClassOf [poison](http://purl.obolibrary.org/obo/CHEBI_64909) + + + +### neurotransmitter `http://purl.obolibrary.org/obo/CHEBI_25512` +#### Removed +- [neurotransmitter](http://purl.obolibrary.org/obo/CHEBI_25512) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25512" + +- [neurotransmitter](http://purl.obolibrary.org/obo/CHEBI_25512) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neurotransmitter" + +- [neurotransmitter](http://purl.obolibrary.org/obo/CHEBI_25512) [label](http://www.w3.org/2000/01/rdf-schema#label) "neurotransmitter" + +- [neurotransmitter](http://purl.obolibrary.org/obo/CHEBI_25512) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [neurotransmitter](http://purl.obolibrary.org/obo/CHEBI_25512) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [neurotransmitter](http://purl.obolibrary.org/obo/CHEBI_25512) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An endogenous compound that is used to transmit information across the synapse between a neuron and another cell." + +- [neurotransmitter](http://purl.obolibrary.org/obo/CHEBI_25512) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "neurotransmitters" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [neurotransmitter](http://purl.obolibrary.org/obo/CHEBI_25512) + +- [neurotransmitter](http://purl.obolibrary.org/obo/CHEBI_25512) SubClassOf [molecular messenger](http://purl.obolibrary.org/obo/CHEBI_33280) + + + +### neurotransmitter agent `http://purl.obolibrary.org/obo/CHEBI_35942` +#### Removed +- [neurotransmitter agent](http://purl.obolibrary.org/obo/CHEBI_35942) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [neurotransmitter agent](http://purl.obolibrary.org/obo/CHEBI_35942) [label](http://www.w3.org/2000/01/rdf-schema#label) "neurotransmitter agent" + +- [neurotransmitter agent](http://purl.obolibrary.org/obo/CHEBI_35942) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function." + +- [neurotransmitter agent](http://purl.obolibrary.org/obo/CHEBI_35942) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "neurotransmitter agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [neurotransmitter agent](http://purl.obolibrary.org/obo/CHEBI_35942) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35942" + +- [neurotransmitter agent](http://purl.obolibrary.org/obo/CHEBI_35942) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [neurotransmitter agent](http://purl.obolibrary.org/obo/CHEBI_35942) + +- [neurotransmitter agent](http://purl.obolibrary.org/obo/CHEBI_35942) SubClassOf [pharmacological role](http://purl.obolibrary.org/obo/CHEBI_52210) + +- [neurotransmitter agent](http://purl.obolibrary.org/obo/CHEBI_35942) SubClassOf [drug](http://purl.obolibrary.org/obo/CHEBI_23888) + + + +### neutrophilic metamyelocyte `http://purl.obolibrary.org/obo/CL_0000582` +#### Removed +- [neutrophilic metamyelocyte](http://purl.obolibrary.org/obo/CL_0000582) EquivalentTo [immature neutrophil](http://purl.obolibrary.org/obo/CL_0000776) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [acidophilic cytoplasm](http://purl.obolibrary.org/obo/CL_0017502)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [reniform nucleus](http://purl.obolibrary.org/obo/CL_0017507)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [heterochromatin](http://purl.obolibrary.org/obo/GO_0000792)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [tertiary granule](http://purl.obolibrary.org/obo/GO_0070820)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [transcription factor PU.1](http://purl.obolibrary.org/obo/PR_000001944)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein epsilon](http://purl.obolibrary.org/obo/PR_000005310)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [neutrophil gelatinase-associated lipocalin](http://purl.obolibrary.org/obo/PR_000009725)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [lactotransferrin](http://purl.obolibrary.org/obo/PR_000009978)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [myeloperoxidase](http://purl.obolibrary.org/obo/PR_000010543)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-(1,3)-fucosyltransferase 4](http://purl.obolibrary.org/obo/PR_000001456)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD33 molecule](http://purl.obolibrary.org/obo/PR_000001892)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [aminopeptidase N](http://purl.obolibrary.org/obo/PR_000002031)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [fMet-Leu-Phe receptor](http://purl.obolibrary.org/obo/PR_000001580)) + +- [neutrophilic metamyelocyte](http://purl.obolibrary.org/obo/CL_0000582) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [fMet-Leu-Phe receptor](http://purl.obolibrary.org/obo/PR_000001580) + +#### Added +- [neutrophilic metamyelocyte](http://purl.obolibrary.org/obo/CL_0000582) EquivalentTo [immature neutrophil](http://purl.obolibrary.org/obo/CL_0000776) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [acidophilic cytoplasm](http://purl.obolibrary.org/obo/CL_0017502)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [reniform nucleus](http://purl.obolibrary.org/obo/CL_0017507)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [heterochromatin](http://purl.obolibrary.org/obo/GO_0000792)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [tertiary granule](http://purl.obolibrary.org/obo/GO_0070820)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [transcription factor PU.1](http://purl.obolibrary.org/obo/PR_000001944)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein epsilon](http://purl.obolibrary.org/obo/PR_000005310)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [neutrophil gelatinase-associated lipocalin](http://purl.obolibrary.org/obo/PR_000009725)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [lactotransferrin](http://purl.obolibrary.org/obo/PR_000009978)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [myeloperoxidase](http://purl.obolibrary.org/obo/PR_000010543)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [fMet-Leu-Phe receptor](http://purl.obolibrary.org/obo/PR_000001580)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-(1,3)-fucosyltransferase 4](http://purl.obolibrary.org/obo/PR_000001456)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD33 molecule](http://purl.obolibrary.org/obo/PR_000001892)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [aminopeptidase N](http://purl.obolibrary.org/obo/PR_000002031)) + +- [neutrophilic metamyelocyte](http://purl.obolibrary.org/obo/CL_0000582) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [fMet-Leu-Phe receptor](http://purl.obolibrary.org/obo/PR_000001580) + + +### neutrophilic myelocyte `http://purl.obolibrary.org/obo/CL_0000580` +#### Removed +- [neutrophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000580) EquivalentTo [immature neutrophil](http://purl.obolibrary.org/obo/CL_0000776) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [acidophilic cytoplasm](http://purl.obolibrary.org/obo/CL_0017502)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [transcription factor PU.1](http://purl.obolibrary.org/obo/PR_000001944)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein epsilon](http://purl.obolibrary.org/obo/PR_000005310)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [neutrophil gelatinase-associated lipocalin](http://purl.obolibrary.org/obo/PR_000009725)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [lactotransferrin](http://purl.obolibrary.org/obo/PR_000009978)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [myeloperoxidase](http://purl.obolibrary.org/obo/PR_000010543)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-(1,3)-fucosyltransferase 4](http://purl.obolibrary.org/obo/PR_000001456)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD33 molecule](http://purl.obolibrary.org/obo/PR_000001892)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [aminopeptidase N](http://purl.obolibrary.org/obo/PR_000002031)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [tertiary granule](http://purl.obolibrary.org/obo/GO_0070820)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) + +- [neutrophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000580) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483) + +- [neutrophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000580) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [tertiary granule](http://purl.obolibrary.org/obo/GO_0070820) + +#### Added +- [neutrophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000580) EquivalentTo [immature neutrophil](http://purl.obolibrary.org/obo/CL_0000776) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [acidophilic cytoplasm](http://purl.obolibrary.org/obo/CL_0017502)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [transcription factor PU.1](http://purl.obolibrary.org/obo/PR_000001944)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein epsilon](http://purl.obolibrary.org/obo/PR_000005310)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [neutrophil gelatinase-associated lipocalin](http://purl.obolibrary.org/obo/PR_000009725)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [lactotransferrin](http://purl.obolibrary.org/obo/PR_000009978)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [myeloperoxidase](http://purl.obolibrary.org/obo/PR_000010543)) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [tertiary granule](http://purl.obolibrary.org/obo/GO_0070820)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-(1,3)-fucosyltransferase 4](http://purl.obolibrary.org/obo/PR_000001456)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD33 molecule](http://purl.obolibrary.org/obo/PR_000001892)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [aminopeptidase N](http://purl.obolibrary.org/obo/PR_000002031)) + +- [neutrophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000580) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483) + +- [neutrophilic myelocyte](http://purl.obolibrary.org/obo/CL_0000580) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [tertiary granule](http://purl.obolibrary.org/obo/GO_0070820) + + +### neutrophilic promyelocyte `http://purl.obolibrary.org/obo/CL_0000564` +#### Removed +- [neutrophilic promyelocyte](http://purl.obolibrary.org/obo/CL_0000564) EquivalentTo [promyelocyte](http://purl.obolibrary.org/obo/CL_0000836) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [transcription factor PU.1](http://purl.obolibrary.org/obo/PR_000001944)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [erythroid transcription factor](http://purl.obolibrary.org/obo/PR_000007857)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [myeloperoxidase](http://purl.obolibrary.org/obo/PR_000010543)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [runt-related transcription factor 1](http://purl.obolibrary.org/obo/PR_000014362)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [neutrophil differentiation](http://purl.obolibrary.org/obo/GO_0030223)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [lactotransferrin](http://purl.obolibrary.org/obo/PR_000009978)) + +- [neutrophilic promyelocyte](http://purl.obolibrary.org/obo/CL_0000564) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [lactotransferrin](http://purl.obolibrary.org/obo/PR_000009978) + +#### Added +- [neutrophilic promyelocyte](http://purl.obolibrary.org/obo/CL_0000564) EquivalentTo [promyelocyte](http://purl.obolibrary.org/obo/CL_0000836) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [transcription factor PU.1](http://purl.obolibrary.org/obo/PR_000001944)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [CCAAT/enhancer-binding protein alpha](http://purl.obolibrary.org/obo/PR_000005307)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [erythroid transcription factor](http://purl.obolibrary.org/obo/PR_000007857)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [myeloperoxidase](http://purl.obolibrary.org/obo/PR_000010543)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [runt-related transcription factor 1](http://purl.obolibrary.org/obo/PR_000014362)) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [lactotransferrin](http://purl.obolibrary.org/obo/PR_000009978)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [neutrophil differentiation](http://purl.obolibrary.org/obo/GO_0030223)) + +- [neutrophilic promyelocyte](http://purl.obolibrary.org/obo/CL_0000564) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [lactotransferrin](http://purl.obolibrary.org/obo/PR_000009978) + + +### never in taxon `http://purl.obolibrary.org/obo/RO_0002161` +#### Removed +- [never in taxon](http://purl.obolibrary.org/obo/RO_0002161) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall"@en + +#### Added +- [never in taxon](http://purl.obolibrary.org/obo/RO_0002161) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### nitric oxide `http://purl.obolibrary.org/obo/CHEBI_16480` +#### Removed +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nitric oxide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(NO)(.)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00533" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:451" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "EDRF" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxoazanyl" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nitric_oxide" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "endothelium-derived relaxing factor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D00074" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A nitrogen oxide which is a free radical, each molecule of which consists of one nitrogen and one oxygen atom." + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Stickstoffmonoxid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [formula](http://purl.obolibrary.org/obo/chebi/formula) "NO" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[N]=O" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(.)NO" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:44452" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxido nitrico" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mononitrogen monoxide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:16480" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monoxido de nitrogeno" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "MWUXSHHQAYIFBG-UHFFFAOYSA-N" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[NO]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MolBase" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB00435" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Nitric oxide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:25546" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [label](http://www.w3.org/2000/01/rdf-schema#label) "nitric oxide" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:7583" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "29.99799" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Stickstoff(II)-oxid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:10102-43-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxyde azotique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [mass](http://purl.obolibrary.org/obo/chebi/mass) "30.00614" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NO(.)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14657" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:10102-43-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nitrogen monooxide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxyde nitrique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxido de nitrogeno(II)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nitrogen monoxide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Nitrogen monoxide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/NO/c1-2" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:3587257" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "monoxyde d'azote" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nitrosyl" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:NO" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:10102-43-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MolBase:943" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxidonitrogen(.)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NO" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [signalling molecule](http://purl.obolibrary.org/obo/CHEBI_62488) + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) SubClassOf [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764) + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [neurotransmitter](http://purl.obolibrary.org/obo/CHEBI_25512) + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) SubClassOf [inorganic radical](http://purl.obolibrary.org/obo/CHEBI_36871) + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [radical scavenger](http://purl.obolibrary.org/obo/CHEBI_48578) + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) SubClassOf [nitrogen oxide](http://purl.obolibrary.org/obo/CHEBI_35196) + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [bronchodilator agent](http://purl.obolibrary.org/obo/CHEBI_35523) + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) + +- [nitric oxide](http://purl.obolibrary.org/obo/CHEBI_16480) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [vasodilator agent](http://purl.obolibrary.org/obo/CHEBI_35620) + + + +### nitric oxide binding `http://purl.obolibrary.org/obo/GO_0070026` +#### Removed +- [nitric oxide binding](http://purl.obolibrary.org/obo/GO_0070026) [label](http://www.w3.org/2000/01/rdf-schema#label) "nitric oxide binding" + +- [nitric oxide binding](http://purl.obolibrary.org/obo/GO_0070026) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0070026" + +- [nitric oxide binding](http://purl.obolibrary.org/obo/GO_0070026) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nitrogen monoxide binding" + +- [nitric oxide binding](http://purl.obolibrary.org/obo/GO_0070026) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to nitric oxide (NO)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ecd" + +- [nitric oxide binding](http://purl.obolibrary.org/obo/GO_0070026) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [nitric oxide binding](http://purl.obolibrary.org/obo/GO_0070026) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nitrosyl binding" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CHEBI:16480" + +- [nitric oxide binding](http://purl.obolibrary.org/obo/GO_0070026) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "NO binding" + +- Class: [nitric oxide binding](http://purl.obolibrary.org/obo/GO_0070026) + +- [nitric oxide binding](http://purl.obolibrary.org/obo/GO_0070026) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [nitrogen oxide](http://purl.obolibrary.org/obo/CHEBI_35196)) + +- [nitric oxide binding](http://purl.obolibrary.org/obo/GO_0070026) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + +- [nitric oxide binding](http://purl.obolibrary.org/obo/GO_0070026) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [nitrogen oxide](http://purl.obolibrary.org/obo/CHEBI_35196) + + + +### nitric oxide metabolic process `http://purl.obolibrary.org/obo/GO_0046209` +#### Removed +- [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209) SubClassOf [reactive nitrogen species metabolic process](http://purl.obolibrary.org/obo/GO_2001057) + +#### Added +- [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### nitric oxide transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0030184` +#### Removed +- [nitric oxide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0030184) SubClassOf [inorganic molecular entity transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015318) + +#### Added +- [nitric oxide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0030184) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + +### nitric oxide transport `http://purl.obolibrary.org/obo/GO_0030185` +#### Removed +- [nitric oxide transport](http://purl.obolibrary.org/obo/GO_0030185) SubClassOf [nitrogen compound transport](http://purl.obolibrary.org/obo/GO_0071705) + +#### Added +- [nitric oxide transport](http://purl.obolibrary.org/obo/GO_0030185) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### nitrogen atom `http://purl.obolibrary.org/obo/CHEBI_25555` +#### Removed +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nitrogen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) [mass](http://purl.obolibrary.org/obo/chebi/mass) "14.007" + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "14.00307" + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nitrogeno" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) [label](http://www.w3.org/2000/01/rdf-schema#label) "nitrogen atom" + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) [formula](http://purl.obolibrary.org/obo/chebi/formula) "N" + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nitrogen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "7N" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25555" + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "azote" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WebElements:N" + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "N" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Stickstoff" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) SubClassOf [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) SubClassOf [pnictogen](http://purl.obolibrary.org/obo/CHEBI_33300) + +- [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [macronutrient](http://purl.obolibrary.org/obo/CHEBI_33937) + + + +### nitrogen fixing cell `http://purl.obolibrary.org/obo/CL_0000725` +#### Removed +- [nitrogen fixing cell](http://purl.obolibrary.org/obo/CL_0000725) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### nitrogen hydride `http://purl.obolibrary.org/obo/CHEBI_35106` +#### Removed +- [nitrogen hydride](http://purl.obolibrary.org/obo/CHEBI_35106) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [nitrogen hydride](http://purl.obolibrary.org/obo/CHEBI_35106) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [nitrogen hydride](http://purl.obolibrary.org/obo/CHEBI_35106) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35106" + +- [nitrogen hydride](http://purl.obolibrary.org/obo/CHEBI_35106) [label](http://www.w3.org/2000/01/rdf-schema#label) "nitrogen hydride" + +- [nitrogen hydride](http://purl.obolibrary.org/obo/CHEBI_35106) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nitrogen hydrides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [nitrogen hydride](http://purl.obolibrary.org/obo/CHEBI_35106) + +- [nitrogen hydride](http://purl.obolibrary.org/obo/CHEBI_35106) SubClassOf [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) + +- [nitrogen hydride](http://purl.obolibrary.org/obo/CHEBI_35106) SubClassOf [pnictogen hydride](http://purl.obolibrary.org/obo/CHEBI_35881) + + + +### nitrogen molecular entity `http://purl.obolibrary.org/obo/CHEBI_51143` +#### Removed +- [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Nitrogenous compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nitrogen molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:7594" + +- [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:25556" + +- [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nitrogen compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) [label](http://www.w3.org/2000/01/rdf-schema#label) "nitrogen molecular entity" + +- [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C06061" + +- [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nitrogen atom](http://purl.obolibrary.org/obo/CHEBI_25555) + +- [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) SubClassOf [pnictogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33302) + + + +### nitrogen oxide `http://purl.obolibrary.org/obo/CHEBI_35196` +#### Removed +- [nitrogen oxide](http://purl.obolibrary.org/obo/CHEBI_35196) [label](http://www.w3.org/2000/01/rdf-schema#label) "nitrogen oxide" + +- [nitrogen oxide](http://purl.obolibrary.org/obo/CHEBI_35196) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxides of nitrogen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nitrogen oxide](http://purl.obolibrary.org/obo/CHEBI_35196) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nitrogen oxides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nitrogen oxide](http://purl.obolibrary.org/obo/CHEBI_35196) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [nitrogen oxide](http://purl.obolibrary.org/obo/CHEBI_35196) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35196" + +- [nitrogen oxide](http://purl.obolibrary.org/obo/CHEBI_35196) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [nitrogen oxide](http://purl.obolibrary.org/obo/CHEBI_35196) + +- [nitrogen oxide](http://purl.obolibrary.org/obo/CHEBI_35196) SubClassOf [inorganic oxide](http://purl.obolibrary.org/obo/CHEBI_24836) + +- [nitrogen oxide](http://purl.obolibrary.org/obo/CHEBI_35196) SubClassOf [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) + + + +### nitrogenous compound fermentation `http://purl.obolibrary.org/obo/GO_0019666` +#### Removed +- [nitrogenous compound fermentation](http://purl.obolibrary.org/obo/GO_0019666) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [nitrogenous compound fermentation](http://purl.obolibrary.org/obo/GO_0019666) [label](http://www.w3.org/2000/01/rdf-schema#label) "nitrogenous compound fermentation" + +- [nitrogenous compound fermentation](http://purl.obolibrary.org/obo/GO_0019666) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "nitrogenous compound catabolic process" + +- [nitrogenous compound fermentation](http://purl.obolibrary.org/obo/GO_0019666) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0019666" + +- [nitrogenous compound fermentation](http://purl.obolibrary.org/obo/GO_0019666) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- Class: [nitrogenous compound fermentation](http://purl.obolibrary.org/obo/GO_0019666) + +- [nitrogenous compound fermentation](http://purl.obolibrary.org/obo/GO_0019666) EquivalentTo [fermentation](http://purl.obolibrary.org/obo/GO_0006113) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143)) + +- [nitrogenous compound fermentation](http://purl.obolibrary.org/obo/GO_0019666) SubClassOf [fermentation](http://purl.obolibrary.org/obo/GO_0006113) + +- [nitrogenous compound fermentation](http://purl.obolibrary.org/obo/GO_0019666) SubClassOf [nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0006807) + +- [nitrogenous compound fermentation](http://purl.obolibrary.org/obo/GO_0019666) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) + + + +### non-classical monocyte `http://purl.obolibrary.org/obo/CL_0000875` +#### Removed +- [non-classical monocyte](http://purl.obolibrary.org/obo/CL_0000875) EquivalentTo [monocyte](http://purl.obolibrary.org/obo/CL_0000576) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [decreased size](http://purl.obolibrary.org/obo/PATO_0000587)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [lymphocyte costimulation](http://purl.obolibrary.org/obo/GO_0031294)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [monocyte differentiation](http://purl.obolibrary.org/obo/GO_0030224)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) + +- [non-classical monocyte](http://purl.obolibrary.org/obo/CL_0000875) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [non-classical monocyte](http://purl.obolibrary.org/obo/CL_0000875) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [non-classical monocyte](http://purl.obolibrary.org/obo/CL_0000875) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +#### Added +- [non-classical monocyte](http://purl.obolibrary.org/obo/CL_0000875) EquivalentTo [monocyte](http://purl.obolibrary.org/obo/CL_0000576) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [decreased size](http://purl.obolibrary.org/obo/PATO_0000587)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [lymphocyte costimulation](http://purl.obolibrary.org/obo/GO_0031294)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [monocyte differentiation](http://purl.obolibrary.org/obo/GO_0030224)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206)) + +- [non-classical monocyte](http://purl.obolibrary.org/obo/CL_0000875) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [non-classical monocyte](http://purl.obolibrary.org/obo/CL_0000875) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [non-classical monocyte](http://purl.obolibrary.org/obo/CL_0000875) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + + +### non-covalently-bound molecular entity `http://purl.obolibrary.org/obo/CHEBI_50967` +#### Removed +- [non-covalently-bound molecular entity](http://purl.obolibrary.org/obo/CHEBI_50967) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Systems consisting of two or more molecular entities held together by non-covalent interactions." + +- [non-covalently-bound molecular entity](http://purl.obolibrary.org/obo/CHEBI_50967) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [non-covalently-bound molecular entity](http://purl.obolibrary.org/obo/CHEBI_50967) [label](http://www.w3.org/2000/01/rdf-schema#label) "non-covalently-bound molecular entity" + +- [non-covalently-bound molecular entity](http://purl.obolibrary.org/obo/CHEBI_50967) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50967" + +- [non-covalently-bound molecular entity](http://purl.obolibrary.org/obo/CHEBI_50967) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "non-covalently-bound molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [non-covalently-bound molecular entity](http://purl.obolibrary.org/obo/CHEBI_50967) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [non-covalently-bound molecular entity](http://purl.obolibrary.org/obo/CHEBI_50967) + +- [non-covalently-bound molecular entity](http://purl.obolibrary.org/obo/CHEBI_50967) SubClassOf [polyatomic entity](http://purl.obolibrary.org/obo/CHEBI_36357) + + + +### non-proteinogenic amino acid `http://purl.obolibrary.org/obo/CHEBI_83820` +#### Removed +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Non-proteinogenic_amino_acids" + +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "non-proteinogenic amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "non-coded amino-acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "non-canonical amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "non-coded amino-acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "non-coded amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any amino-acid that is not naturally encoded in the genetic code of any organism." + +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "non-proteinogenic amino-acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:83820" + +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "non-canonical amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) [label](http://www.w3.org/2000/01/rdf-schema#label) "non-proteinogenic amino acid" + +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "non-canonical amino-acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "non-coded amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "non-proteinogenic amino-acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "non-canonical amino-acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) + +- [non-proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83820) SubClassOf [amino acid](http://purl.obolibrary.org/obo/CHEBI_33709) + + + +### nongranular leukocyte `http://purl.obolibrary.org/obo/CL_0002087` +#### Removed +- [nongranular leukocyte](http://purl.obolibrary.org/obo/CL_0002087) EquivalentTo [leukocyte](http://purl.obolibrary.org/obo/CL_0000738) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [secretory granule](http://purl.obolibrary.org/obo/GO_0030141)) + +- [nongranular leukocyte](http://purl.obolibrary.org/obo/CL_0002087) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [secretory granule](http://purl.obolibrary.org/obo/GO_0030141) + +#### Added +- [nongranular leukocyte](http://purl.obolibrary.org/obo/CL_0002087) EquivalentTo [leukocyte](http://purl.obolibrary.org/obo/CL_0000738) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [secretory granule](http://purl.obolibrary.org/obo/GO_0030141)) + +- [nongranular leukocyte](http://purl.obolibrary.org/obo/CL_0002087) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [secretory granule](http://purl.obolibrary.org/obo/GO_0030141) + + +### nonmetal atom `http://purl.obolibrary.org/obo/CHEBI_25585` +#### Removed +- [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "no metales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "non-metaux" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nonmetal" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25585" + +- [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Nichtmetalle" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Nichtmetall" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "non-metal" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nonmetals" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "no metal" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) [label](http://www.w3.org/2000/01/rdf-schema#label) "nonmetal atom" + +- [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nonmetal" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- Class: [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) + +- [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) SubClassOf [atom](http://purl.obolibrary.org/obo/CHEBI_33250) + + + +### noradrenaline `http://purl.obolibrary.org/obo/CHEBI_33569` +#### Removed +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LINCS:LSM-5181" + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:138-65-8" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2" + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "SFLSHLFXELFNJZ-UHFFFAOYSA-N" + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:2210994" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "NCC(O)c1ccc(O)c(O)c1" + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "4-(2-amino-1-hydroxyethyl)benzene-1,2-diol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted." + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [mass](http://purl.obolibrary.org/obo/chebi/mass) "169.17788" + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "169.07389" + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "noradrenalina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33569" + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:863925" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C8H11NO3" + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "norepinephrine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:138-65-8" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) [label](http://www.w3.org/2000/01/rdf-schema#label) "noradrenaline" + +- Class: [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76967) + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) SubClassOf [catecholamine](http://purl.obolibrary.org/obo/CHEBI_33567) + +- [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) + + + +### noradrenaline(1+) `http://purl.obolibrary.org/obo/CHEBI_166902` +#### Removed +- [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:166902" + +- [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1" + +- [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) [mass](http://purl.obolibrary.org/obo/chebi/mass) "170.187" + +- [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+1" + +- [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#2_STAR) + +- [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "SFLSHLFXELFNJZ-UHFFFAOYSA-O" + +- [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "noradrenaline" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) [label](http://www.w3.org/2000/01/rdf-schema#label) "noradrenaline(1+)" + +- [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "170.08117" + +- [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C8H12NO3" + +- [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C1=CC(=CC(=C1O)O)C(C[NH3+])O" + +- Class: [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) + +- [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [noradrenaline](http://purl.obolibrary.org/obo/CHEBI_33569) + +- [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) SubClassOf [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) + +- [noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_166902) SubClassOf [organic cation](http://purl.obolibrary.org/obo/CHEBI_25697) + + + +### norepinephrine binding `http://purl.obolibrary.org/obo/GO_0051380` +#### Removed +- [norepinephrine binding](http://purl.obolibrary.org/obo/GO_0051380) SubClassOf [cation binding](http://purl.obolibrary.org/obo/GO_0043169) + +#### Added +- [norepinephrine binding](http://purl.obolibrary.org/obo/GO_0051380) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### norepinephrine biosynthetic process `http://purl.obolibrary.org/obo/GO_0042421` +#### Removed +- [norepinephrine biosynthetic process](http://purl.obolibrary.org/obo/GO_0042421) SubClassOf [organic substance biosynthetic process](http://purl.obolibrary.org/obo/GO_1901576) + +#### Added +- [norepinephrine biosynthetic process](http://purl.obolibrary.org/obo/GO_0042421) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### norepinephrine catabolic process `http://purl.obolibrary.org/obo/GO_0042422` +#### Removed +- [norepinephrine catabolic process](http://purl.obolibrary.org/obo/GO_0042422) SubClassOf [organic substance catabolic process](http://purl.obolibrary.org/obo/GO_1901575) + +#### Added +- [norepinephrine catabolic process](http://purl.obolibrary.org/obo/GO_0042422) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### norepinephrine metabolic process `http://purl.obolibrary.org/obo/GO_0042415` +#### Removed +- [norepinephrine metabolic process](http://purl.obolibrary.org/obo/GO_0042415) SubClassOf [nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0006807) + +- [norepinephrine metabolic process](http://purl.obolibrary.org/obo/GO_0042415) SubClassOf [organic substance metabolic process](http://purl.obolibrary.org/obo/GO_0071704) + +#### Added +- [norepinephrine metabolic process](http://purl.obolibrary.org/obo/GO_0042415) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### norepinephrine secretion, neurotransmission `http://purl.obolibrary.org/obo/GO_0061533` + +#### Added +- [norepinephrine secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0061533) EquivalentTo [neurotransmitter secretion](http://purl.obolibrary.org/obo/GO_0007269) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [(R)-noradrenaline(1+)](http://purl.obolibrary.org/obo/CHEBI_72587)) + + +### norepinephrine transport `http://purl.obolibrary.org/obo/GO_0015874` +#### Removed +- [norepinephrine transport](http://purl.obolibrary.org/obo/GO_0015874) SubClassOf [organic cation transport](http://purl.obolibrary.org/obo/GO_0015695) + + + +### nuclear particle `http://purl.obolibrary.org/obo/CHEBI_36347` +#### Removed +- [nuclear particle](http://purl.obolibrary.org/obo/CHEBI_36347) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36347" + +- [nuclear particle](http://purl.obolibrary.org/obo/CHEBI_36347) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nuclear particle" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [nuclear particle](http://purl.obolibrary.org/obo/CHEBI_36347) [label](http://www.w3.org/2000/01/rdf-schema#label) "nuclear particle" + +- [nuclear particle](http://purl.obolibrary.org/obo/CHEBI_36347) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [nuclear particle](http://purl.obolibrary.org/obo/CHEBI_36347) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [nuclear particle](http://purl.obolibrary.org/obo/CHEBI_36347) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A nucleus or any of its constituents in any of their energy states." + +- Class: [nuclear particle](http://purl.obolibrary.org/obo/CHEBI_36347) + +- [nuclear particle](http://purl.obolibrary.org/obo/CHEBI_36347) SubClassOf [subatomic particle](http://purl.obolibrary.org/obo/CHEBI_36342) + + + +### nucleated thrombocyte `http://purl.obolibrary.org/obo/CL_0000762` +#### Removed +- [nucleated thrombocyte](http://purl.obolibrary.org/obo/CL_0000762) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### nucleic acid `http://purl.obolibrary.org/obo/CHEBI_33696` +#### Removed +- [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33696" + +- [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acides nucleiques" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Nukleinsaeuren" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) [label](http://www.w3.org/2000/01/rdf-schema#label) "nucleic acid" + +- [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acido nucleico" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." + +- [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acidos nucleicos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NA" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acide nucleique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Nukleinsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) SubClassOf [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) + +- [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [canonical nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33791) + +- [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [canonical nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50297) + + + +### nucleic acid binding `http://purl.obolibrary.org/obo/GO_0003676` +#### Removed +- [nucleic acid binding](http://purl.obolibrary.org/obo/GO_0003676) SubClassOf [organic cyclic compound binding](http://purl.obolibrary.org/obo/GO_0097159) + +- [nucleic acid binding](http://purl.obolibrary.org/obo/GO_0003676) SubClassOf [heterocyclic compound binding](http://purl.obolibrary.org/obo/GO_1901363) + +#### Added +- [nucleic acid binding](http://purl.obolibrary.org/obo/GO_0003676) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### nucleic acid metabolic process `http://purl.obolibrary.org/obo/GO_0090304` +#### Removed +- [nucleic acid metabolic process](http://purl.obolibrary.org/obo/GO_0090304) SubClassOf [nucleobase-containing compound metabolic process](http://purl.obolibrary.org/obo/GO_0006139) + +- [nucleic acid metabolic process](http://purl.obolibrary.org/obo/GO_0090304) SubClassOf [macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0043170) + +#### Added +- [nucleic acid metabolic process](http://purl.obolibrary.org/obo/GO_0090304) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### nucleic acid transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0051032` +#### Removed +- [nucleic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051032) SubClassOf [nucleobase-containing compound transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015932) + +- [nucleic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051032) SubClassOf [macromolecule transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022884) + +#### Added +- [nucleic acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051032) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + +### nucleic acid transport `http://purl.obolibrary.org/obo/GO_0050657` +#### Removed +- [nucleic acid transport](http://purl.obolibrary.org/obo/GO_0050657) SubClassOf [nucleobase-containing compound transport](http://purl.obolibrary.org/obo/GO_0015931) + +#### Added +- [nucleic acid transport](http://purl.obolibrary.org/obo/GO_0050657) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### nucleobase `http://purl.obolibrary.org/obo/CHEBI_18282` +#### Removed +- [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:2995" + +- [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Base" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00701" + +- [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleobases" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13873" + +- [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:18282" + +- [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nucleobase" + +- [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) [label](http://www.w3.org/2000/01/rdf-schema#label) "nucleobase" + +- [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:25598" + +- [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "That part of DNA or RNA that may be involved in pairing." + +- [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) + +- [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) SubClassOf [organonitrogen heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_38101) + + + +### nucleobase binding `http://purl.obolibrary.org/obo/GO_0002054` +#### Removed +- [nucleobase binding](http://purl.obolibrary.org/obo/GO_0002054) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:hjd" + +- [nucleobase binding](http://purl.obolibrary.org/obo/GO_0002054) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0002054" + +- [nucleobase binding](http://purl.obolibrary.org/obo/GO_0002054) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_pir](http://purl.obolibrary.org/obo/go#goslim_pir) + +- [nucleobase binding](http://purl.obolibrary.org/obo/GO_0002054) [label](http://www.w3.org/2000/01/rdf-schema#label) "nucleobase binding" + +- [nucleobase binding](http://purl.obolibrary.org/obo/GO_0002054) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- Class: [nucleobase binding](http://purl.obolibrary.org/obo/GO_0002054) + +- [nucleobase binding](http://purl.obolibrary.org/obo/GO_0002054) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282)) + +- [nucleobase binding](http://purl.obolibrary.org/obo/GO_0002054) SubClassOf [heterocyclic compound binding](http://purl.obolibrary.org/obo/GO_1901363) + +- [nucleobase binding](http://purl.obolibrary.org/obo/GO_0002054) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) + +- [nucleobase binding](http://purl.obolibrary.org/obo/GO_0002054) SubClassOf [small molecule binding](http://purl.obolibrary.org/obo/GO_0036094) + +- [nucleobase binding](http://purl.obolibrary.org/obo/GO_0002054) SubClassOf [organic cyclic compound binding](http://purl.obolibrary.org/obo/GO_0097159) + + + +### nucleobase biosynthetic process `http://purl.obolibrary.org/obo/GO_0046112` +#### Removed +- [nucleobase biosynthetic process](http://purl.obolibrary.org/obo/GO_0046112) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleobase anabolism" + +- [nucleobase biosynthetic process](http://purl.obolibrary.org/obo/GO_0046112) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleobase synthesis" + +- [nucleobase biosynthetic process](http://purl.obolibrary.org/obo/GO_0046112) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [nucleobase biosynthetic process](http://purl.obolibrary.org/obo/GO_0046112) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleobase biosynthesis" + +- [nucleobase biosynthetic process](http://purl.obolibrary.org/obo/GO_0046112) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleobase formation" + +- [nucleobase biosynthetic process](http://purl.obolibrary.org/obo/GO_0046112) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046112" + +- [nucleobase biosynthetic process](http://purl.obolibrary.org/obo/GO_0046112) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [nucleobase biosynthetic process](http://purl.obolibrary.org/obo/GO_0046112) [label](http://www.w3.org/2000/01/rdf-schema#label) "nucleobase biosynthetic process" + +- Class: [nucleobase biosynthetic process](http://purl.obolibrary.org/obo/GO_0046112) + +- [nucleobase biosynthetic process](http://purl.obolibrary.org/obo/GO_0046112) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282)) + +- [nucleobase biosynthetic process](http://purl.obolibrary.org/obo/GO_0046112) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) + +- [nucleobase biosynthetic process](http://purl.obolibrary.org/obo/GO_0046112) SubClassOf [organonitrogen compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901566) + +- [nucleobase biosynthetic process](http://purl.obolibrary.org/obo/GO_0046112) SubClassOf [organic cyclic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901362) + +- [nucleobase biosynthetic process](http://purl.obolibrary.org/obo/GO_0046112) SubClassOf [nucleobase metabolic process](http://purl.obolibrary.org/obo/GO_0009112) + +- [nucleobase biosynthetic process](http://purl.obolibrary.org/obo/GO_0046112) SubClassOf [heterocycle biosynthetic process](http://purl.obolibrary.org/obo/GO_0018130) + + + +### nucleobase catabolic process `http://purl.obolibrary.org/obo/GO_0046113` +#### Removed +- [nucleobase catabolic process](http://purl.obolibrary.org/obo/GO_0046113) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [nucleobase catabolic process](http://purl.obolibrary.org/obo/GO_0046113) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleobase catabolism" + +- [nucleobase catabolic process](http://purl.obolibrary.org/obo/GO_0046113) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleobase degradation" + +- [nucleobase catabolic process](http://purl.obolibrary.org/obo/GO_0046113) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [nucleobase catabolic process](http://purl.obolibrary.org/obo/GO_0046113) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleobase breakdown" + +- [nucleobase catabolic process](http://purl.obolibrary.org/obo/GO_0046113) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046113" + +- [nucleobase catabolic process](http://purl.obolibrary.org/obo/GO_0046113) [label](http://www.w3.org/2000/01/rdf-schema#label) "nucleobase catabolic process" + +- Class: [nucleobase catabolic process](http://purl.obolibrary.org/obo/GO_0046113) + +- [nucleobase catabolic process](http://purl.obolibrary.org/obo/GO_0046113) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282)) + +- [nucleobase catabolic process](http://purl.obolibrary.org/obo/GO_0046113) SubClassOf [organic cyclic compound catabolic process](http://purl.obolibrary.org/obo/GO_1901361) + +- [nucleobase catabolic process](http://purl.obolibrary.org/obo/GO_0046113) SubClassOf [nucleobase metabolic process](http://purl.obolibrary.org/obo/GO_0009112) + +- [nucleobase catabolic process](http://purl.obolibrary.org/obo/GO_0046113) SubClassOf [organonitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_1901565) + +- [nucleobase catabolic process](http://purl.obolibrary.org/obo/GO_0046113) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) + +- [nucleobase catabolic process](http://purl.obolibrary.org/obo/GO_0046113) SubClassOf [heterocycle catabolic process](http://purl.obolibrary.org/obo/GO_0046700) + + + +### nucleobase metabolic process `http://purl.obolibrary.org/obo/GO_0009112` +#### Removed +- [nucleobase metabolic process](http://purl.obolibrary.org/obo/GO_0009112) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleobase metabolism" + +- [nucleobase metabolic process](http://purl.obolibrary.org/obo/GO_0009112) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0009112" + +- [nucleobase metabolic process](http://purl.obolibrary.org/obo/GO_0009112) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ma" + +- [nucleobase metabolic process](http://purl.obolibrary.org/obo/GO_0009112) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [nucleobase metabolic process](http://purl.obolibrary.org/obo/GO_0009112) [label](http://www.w3.org/2000/01/rdf-schema#label) "nucleobase metabolic process" + +- Class: [nucleobase metabolic process](http://purl.obolibrary.org/obo/GO_0009112) + +- [nucleobase metabolic process](http://purl.obolibrary.org/obo/GO_0009112) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282)) + +- [nucleobase metabolic process](http://purl.obolibrary.org/obo/GO_0009112) SubClassOf [nucleobase-containing small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0055086) + +- [nucleobase metabolic process](http://purl.obolibrary.org/obo/GO_0009112) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) + +- [nucleobase metabolic process](http://purl.obolibrary.org/obo/GO_0009112) SubClassOf [organonitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_1901564) + + + +### nucleobase transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015205` +#### Removed +- [nucleobase transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015205) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0015392" + +- [nucleobase transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015205) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [nucleobase transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015205) [label](http://www.w3.org/2000/01/rdf-schema#label) "nucleobase transmembrane transporter activity" + +- [nucleobase transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015205) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015205" + +- [nucleobase transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015205) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- Class: [nucleobase transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015205) + +- [nucleobase transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015205) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282)) + +- [nucleobase transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015205) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) + +- [nucleobase transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015205) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + +- [nucleobase transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015205) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [nucleobase transport](http://purl.obolibrary.org/obo/GO_0015851) + + + +### nucleobase transport `http://purl.obolibrary.org/obo/GO_0015851` +#### Removed +- [nucleobase transport](http://purl.obolibrary.org/obo/GO_0015851) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [nucleobase transport](http://purl.obolibrary.org/obo/GO_0015851) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015851" + +- [nucleobase transport](http://purl.obolibrary.org/obo/GO_0015851) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [nucleobase transport](http://purl.obolibrary.org/obo/GO_0015851) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleobase transmembrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [nucleobase transport](http://purl.obolibrary.org/obo/GO_0015851) [label](http://www.w3.org/2000/01/rdf-schema#label) "nucleobase transport" + +- Class: [nucleobase transport](http://purl.obolibrary.org/obo/GO_0015851) + +- [nucleobase transport](http://purl.obolibrary.org/obo/GO_0015851) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282)) + +- [nucleobase transport](http://purl.obolibrary.org/obo/GO_0015851) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) + +- [nucleobase transport](http://purl.obolibrary.org/obo/GO_0015851) SubClassOf [organic substance transport](http://purl.obolibrary.org/obo/GO_0071702) + +- [nucleobase transport](http://purl.obolibrary.org/obo/GO_0015851) SubClassOf [nitrogen compound transport](http://purl.obolibrary.org/obo/GO_0071705) + + + +### nucleobase-containing compound biosynthetic process `http://purl.obolibrary.org/obo/GO_0034654` +#### Removed +- [nucleobase-containing compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0034654) SubClassOf [heterocycle biosynthetic process](http://purl.obolibrary.org/obo/GO_0018130) + +- [nucleobase-containing compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0034654) SubClassOf [aromatic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0019438) + +- [nucleobase-containing compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0034654) SubClassOf [organic cyclic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901362) + + + +### nucleobase-containing compound catabolic process `http://purl.obolibrary.org/obo/GO_0034655` +#### Removed +- [nucleobase-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0034655) SubClassOf [aromatic compound catabolic process](http://purl.obolibrary.org/obo/GO_0019439) + +- [nucleobase-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0034655) SubClassOf [organic cyclic compound catabolic process](http://purl.obolibrary.org/obo/GO_1901361) + +- [nucleobase-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0034655) SubClassOf [heterocycle catabolic process](http://purl.obolibrary.org/obo/GO_0046700) + + + +### nucleobase-containing compound metabolic process `http://purl.obolibrary.org/obo/GO_0006139` +#### Removed +- [nucleobase-containing compound metabolic process](http://purl.obolibrary.org/obo/GO_0006139) SubClassOf [heterocycle metabolic process](http://purl.obolibrary.org/obo/GO_0046483) + +- [nucleobase-containing compound metabolic process](http://purl.obolibrary.org/obo/GO_0006139) SubClassOf [organic cyclic compound metabolic process](http://purl.obolibrary.org/obo/GO_1901360) + +- [nucleobase-containing compound metabolic process](http://purl.obolibrary.org/obo/GO_0006139) SubClassOf [cellular aromatic compound metabolic process](http://purl.obolibrary.org/obo/GO_0006725) + + + +### nucleobase-containing compound transport `http://purl.obolibrary.org/obo/GO_0015931` +#### Removed +- [nucleobase-containing compound transport](http://purl.obolibrary.org/obo/GO_0015931) SubClassOf [nitrogen compound transport](http://purl.obolibrary.org/obo/GO_0071705) + +- [nucleobase-containing compound transport](http://purl.obolibrary.org/obo/GO_0015931) SubClassOf [organic substance transport](http://purl.obolibrary.org/obo/GO_0071702) + +#### Added +- [nucleobase-containing compound transport](http://purl.obolibrary.org/obo/GO_0015931) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### nucleobase-containing molecular entity `http://purl.obolibrary.org/obo/CHEBI_61120` +#### Removed +- [nucleobase-containing molecular entity](http://purl.obolibrary.org/obo/CHEBI_61120) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [nucleobase-containing molecular entity](http://purl.obolibrary.org/obo/CHEBI_61120) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleobase-containing molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nucleobase-containing molecular entity](http://purl.obolibrary.org/obo/CHEBI_61120) [label](http://www.w3.org/2000/01/rdf-schema#label) "nucleobase-containing molecular entity" + +- [nucleobase-containing molecular entity](http://purl.obolibrary.org/obo/CHEBI_61120) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleobase-containing compound" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "SUBMITTER" + +- [nucleobase-containing molecular entity](http://purl.obolibrary.org/obo/CHEBI_61120) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any compound that has a nucleobase as a part." + +- [nucleobase-containing molecular entity](http://purl.obolibrary.org/obo/CHEBI_61120) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleobase-containing compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nucleobase-containing molecular entity](http://purl.obolibrary.org/obo/CHEBI_61120) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:61120" + +- [nucleobase-containing molecular entity](http://purl.obolibrary.org/obo/CHEBI_61120) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [nucleobase-containing molecular entity](http://purl.obolibrary.org/obo/CHEBI_61120) SubClassOf [heteroarene](http://purl.obolibrary.org/obo/CHEBI_33833) + +- [nucleobase-containing molecular entity](http://purl.obolibrary.org/obo/CHEBI_61120) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [nucleobase](http://purl.obolibrary.org/obo/CHEBI_18282) + +- [nucleobase-containing molecular entity](http://purl.obolibrary.org/obo/CHEBI_61120) SubClassOf [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) + + + +### nucleobase-containing small molecule metabolic process `http://purl.obolibrary.org/obo/GO_0055086` +#### Removed +- [nucleobase-containing small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0055086) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0055086" + +- [nucleobase-containing small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0055086) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:vw" + +- [nucleobase-containing small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0055086) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_yeast](http://purl.obolibrary.org/obo/go#goslim_yeast) + +- [nucleobase-containing small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0055086) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_drosophila](http://purl.obolibrary.org/obo/go#goslim_drosophila) + +- [nucleobase-containing small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0055086) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_pombe](http://purl.obolibrary.org/obo/go#goslim_pombe) + +- [nucleobase-containing small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0055086) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleobase, nucleoside and nucleotide metabolism" + +- [nucleobase-containing small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0055086) [label](http://www.w3.org/2000/01/rdf-schema#label) "nucleobase-containing small molecule metabolic process" + +- [nucleobase-containing small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0055086) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_generic](http://purl.obolibrary.org/obo/go#goslim_generic) + +- [nucleobase-containing small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0055086) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +- [nucleobase-containing small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0055086) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleobase, nucleoside and nucleotide metabolic process" + +- [nucleobase-containing small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0055086) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [nucleobase-containing small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0055086) + +- [nucleobase-containing small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0055086) SubClassOf [small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0044281) + +- [nucleobase-containing small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0055086) SubClassOf [nucleobase-containing compound metabolic process](http://purl.obolibrary.org/obo/GO_0006139) + + + +### nucleon `http://purl.obolibrary.org/obo/CHEBI_33253` +#### Removed +- [nucleon](http://purl.obolibrary.org/obo/CHEBI_33253) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Heavy nuclear particle: proton or neutron." + +- [nucleon](http://purl.obolibrary.org/obo/CHEBI_33253) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Nukleon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nucleon](http://purl.obolibrary.org/obo/CHEBI_33253) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [nucleon](http://purl.obolibrary.org/obo/CHEBI_33253) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33253" + +- [nucleon](http://purl.obolibrary.org/obo/CHEBI_33253) [label](http://www.w3.org/2000/01/rdf-schema#label) "nucleon" + +- [nucleon](http://purl.obolibrary.org/obo/CHEBI_33253) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [nucleon](http://purl.obolibrary.org/obo/CHEBI_33253) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [nucleon](http://purl.obolibrary.org/obo/CHEBI_33253) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Nukleonen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nucleon](http://purl.obolibrary.org/obo/CHEBI_33253) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleons" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nucleon](http://purl.obolibrary.org/obo/CHEBI_33253) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- Class: [nucleon](http://purl.obolibrary.org/obo/CHEBI_33253) + +- [nucleon](http://purl.obolibrary.org/obo/CHEBI_33253) SubClassOf [baryon](http://purl.obolibrary.org/obo/CHEBI_36339) + +- [nucleon](http://purl.obolibrary.org/obo/CHEBI_33253) SubClassOf [nuclear particle](http://purl.obolibrary.org/obo/CHEBI_36347) + + + +### nucleophilic reagent `http://purl.obolibrary.org/obo/CHEBI_59740` +#### Removed +- [nucleophilic reagent](http://purl.obolibrary.org/obo/CHEBI_59740) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:59740" + +- [nucleophilic reagent](http://purl.obolibrary.org/obo/CHEBI_59740) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleophiles" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nucleophilic reagent](http://purl.obolibrary.org/obo/CHEBI_59740) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleophilic reagents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nucleophilic reagent](http://purl.obolibrary.org/obo/CHEBI_59740) [label](http://www.w3.org/2000/01/rdf-schema#label) "nucleophilic reagent" + +- [nucleophilic reagent](http://purl.obolibrary.org/obo/CHEBI_59740) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons." + +- [nucleophilic reagent](http://purl.obolibrary.org/obo/CHEBI_59740) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [nucleophilic reagent](http://purl.obolibrary.org/obo/CHEBI_59740) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [nucleophilic reagent](http://purl.obolibrary.org/obo/CHEBI_59740) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleophile" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [nucleophilic reagent](http://purl.obolibrary.org/obo/CHEBI_59740) + +- [nucleophilic reagent](http://purl.obolibrary.org/obo/CHEBI_59740) SubClassOf [Lewis base](http://purl.obolibrary.org/obo/CHEBI_39144) + +- [nucleophilic reagent](http://purl.obolibrary.org/obo/CHEBI_59740) SubClassOf [reagent](http://purl.obolibrary.org/obo/CHEBI_33893) + + + +### nucleoside residue `http://purl.obolibrary.org/obo/CHEBI_50320` +#### Removed +- [nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_50320) [label](http://www.w3.org/2000/01/rdf-schema#label) "nucleoside residue" + +- [nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_50320) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_50320) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50320" + +- [nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_50320) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_50320) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleoside residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_50320) + +- [nucleoside residue](http://purl.obolibrary.org/obo/CHEBI_50320) SubClassOf [organic group](http://purl.obolibrary.org/obo/CHEBI_33247) + + + +### nucleotide residue `http://purl.obolibrary.org/obo/CHEBI_50319` +#### Removed +- [nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50319) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50319" + +- [nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50319) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleotide residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50319) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50319) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50319) [label](http://www.w3.org/2000/01/rdf-schema#label) "nucleotide residue" + +- Class: [nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50319) + +- [nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50319) SubClassOf [organic group](http://purl.obolibrary.org/obo/CHEBI_33247) + + + +### nutraceutical `http://purl.obolibrary.org/obo/CHEBI_50733` +#### Removed +- [nutraceutical](http://purl.obolibrary.org/obo/CHEBI_50733) [label](http://www.w3.org/2000/01/rdf-schema#label) "nutraceutical" + +- [nutraceutical](http://purl.obolibrary.org/obo/CHEBI_50733) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Food Supplementation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nutraceutical](http://purl.obolibrary.org/obo/CHEBI_50733) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [nutraceutical](http://purl.obolibrary.org/obo/CHEBI_50733) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance." + +- [nutraceutical](http://purl.obolibrary.org/obo/CHEBI_50733) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Nutritional supplement" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nutraceutical](http://purl.obolibrary.org/obo/CHEBI_50733) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Dietary Supplement" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nutraceutical](http://purl.obolibrary.org/obo/CHEBI_50733) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50733" + +- [nutraceutical](http://purl.obolibrary.org/obo/CHEBI_50733) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [nutraceutical](http://purl.obolibrary.org/obo/CHEBI_50733) + +- [nutraceutical](http://purl.obolibrary.org/obo/CHEBI_50733) SubClassOf [drug](http://purl.obolibrary.org/obo/CHEBI_23888) + + + +### nutrient `http://purl.obolibrary.org/obo/CHEBI_33284` +#### Removed +- [nutrient](http://purl.obolibrary.org/obo/CHEBI_33284) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33284" + +- [nutrient](http://purl.obolibrary.org/obo/CHEBI_33284) [label](http://www.w3.org/2000/01/rdf-schema#label) "nutrient" + +- [nutrient](http://purl.obolibrary.org/obo/CHEBI_33284) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [nutrient](http://purl.obolibrary.org/obo/CHEBI_33284) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [nutrient](http://purl.obolibrary.org/obo/CHEBI_33284) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nutrients" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [nutrient](http://purl.obolibrary.org/obo/CHEBI_33284) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A nutrient is a food component that an organism uses to survive and grow." + +- Class: [nutrient](http://purl.obolibrary.org/obo/CHEBI_33284) + +- [nutrient](http://purl.obolibrary.org/obo/CHEBI_33284) SubClassOf [food component](http://purl.obolibrary.org/obo/CHEBI_78295) + + + +### obsolete fusiform initial `http://purl.obolibrary.org/obo/CL_0000009` +#### Removed +- [obsolete fusiform initial](http://purl.obolibrary.org/obo/CL_0000009) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000274" + + + +### odontocyte `http://purl.obolibrary.org/obo/CL_0000140` +#### Removed +- [odontocyte](http://purl.obolibrary.org/obo/CL_0000140) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### olefinic compound `http://purl.obolibrary.org/obo/CHEBI_78840` +#### Removed +- [olefinic compound](http://purl.obolibrary.org/obo/CHEBI_78840) [label](http://www.w3.org/2000/01/rdf-schema#label) "olefinic compound" + +- [olefinic compound](http://purl.obolibrary.org/obo/CHEBI_78840) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [olefinic compound](http://purl.obolibrary.org/obo/CHEBI_78840) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "olefinic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [olefinic compound](http://purl.obolibrary.org/obo/CHEBI_78840) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any organic molecular entity that contains at least one C=C bond." + +- [olefinic compound](http://purl.obolibrary.org/obo/CHEBI_78840) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:78840" + +- [olefinic compound](http://purl.obolibrary.org/obo/CHEBI_78840) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [olefinic compound](http://purl.obolibrary.org/obo/CHEBI_78840) + +- [olefinic compound](http://purl.obolibrary.org/obo/CHEBI_78840) SubClassOf [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) + + + +### olefinic compound biosynthetic process `http://purl.obolibrary.org/obo/GO_0120255` +#### Removed +- [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkene substituted compound anabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0120255" + +- [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkene substituted compound synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/19936"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "krc" + +- [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) [label](http://www.w3.org/2000/01/rdf-schema#label) "olefinic compound biosynthetic process" + +- [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkene substituted compound biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkene substituted compound biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkene substituted compound anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2020-09-02T23:30:20Z" + +- Class: [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) + +- [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [olefinic compound](http://purl.obolibrary.org/obo/CHEBI_78840)) + +- [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) SubClassOf [olefinic compound metabolic process](http://purl.obolibrary.org/obo/GO_0120254) + +- [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) SubClassOf [organic substance biosynthetic process](http://purl.obolibrary.org/obo/GO_1901576) + +- [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [olefinic compound](http://purl.obolibrary.org/obo/CHEBI_78840) + + + +### olefinic compound catabolic process `http://purl.obolibrary.org/obo/GO_0120256` +#### Removed +- [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkene substituted compound breakdown" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkene substituted compound catabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkene substituted compound catabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) [label](http://www.w3.org/2000/01/rdf-schema#label) "olefinic compound catabolic process" + +- [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkene substituted compound degradation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2020-09-02T23:30:41Z" + +- [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0120256" + +- [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "krc" + +- [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/19936"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- Class: [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) + +- [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [olefinic compound](http://purl.obolibrary.org/obo/CHEBI_78840)) + +- [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) SubClassOf [organic substance catabolic process](http://purl.obolibrary.org/obo/GO_1901575) + +- [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) SubClassOf [olefinic compound metabolic process](http://purl.obolibrary.org/obo/GO_0120254) + +- [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [olefinic compound](http://purl.obolibrary.org/obo/CHEBI_78840) + + + +### olefinic compound metabolic process `http://purl.obolibrary.org/obo/GO_0120254` +#### Removed +- [olefinic compound metabolic process](http://purl.obolibrary.org/obo/GO_0120254) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [olefinic compound metabolic process](http://purl.obolibrary.org/obo/GO_0120254) [label](http://www.w3.org/2000/01/rdf-schema#label) "olefinic compound metabolic process" + +- [olefinic compound metabolic process](http://purl.obolibrary.org/obo/GO_0120254) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0120254" + +- [olefinic compound metabolic process](http://purl.obolibrary.org/obo/GO_0120254) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkene substituted compound metabolism" + +- [olefinic compound metabolic process](http://purl.obolibrary.org/obo/GO_0120254) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "alkene substituted compound metabolic process" + +- [olefinic compound metabolic process](http://purl.obolibrary.org/obo/GO_0120254) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2020-09-02T23:13:44Z" + +- [olefinic compound metabolic process](http://purl.obolibrary.org/obo/GO_0120254) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [olefinic compound metabolic process](http://purl.obolibrary.org/obo/GO_0120254) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "krc" + +- [olefinic compound metabolic process](http://purl.obolibrary.org/obo/GO_0120254) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/19936"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- Class: [olefinic compound metabolic process](http://purl.obolibrary.org/obo/GO_0120254) + +- [olefinic compound metabolic process](http://purl.obolibrary.org/obo/GO_0120254) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [olefinic compound](http://purl.obolibrary.org/obo/CHEBI_78840)) + +- [olefinic compound metabolic process](http://purl.obolibrary.org/obo/GO_0120254) SubClassOf [organic substance metabolic process](http://purl.obolibrary.org/obo/GO_0071704) + +- [olefinic compound metabolic process](http://purl.obolibrary.org/obo/GO_0120254) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [olefinic compound](http://purl.obolibrary.org/obo/CHEBI_78840) + + + +### one-carbon compound `http://purl.obolibrary.org/obo/CHEBI_64708` +#### Removed +- [one-carbon compound](http://purl.obolibrary.org/obo/CHEBI_64708) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "one-carbon compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [one-carbon compound](http://purl.obolibrary.org/obo/CHEBI_64708) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [one-carbon compound](http://purl.obolibrary.org/obo/CHEBI_64708) [label](http://www.w3.org/2000/01/rdf-schema#label) "one-carbon compound" + +- [one-carbon compound](http://purl.obolibrary.org/obo/CHEBI_64708) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An organic molecular entity containing a single carbon atom (C1)." + +- [one-carbon compound](http://purl.obolibrary.org/obo/CHEBI_64708) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:64708" + +- [one-carbon compound](http://purl.obolibrary.org/obo/CHEBI_64708) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [one-carbon compound](http://purl.obolibrary.org/obo/CHEBI_64708) + +- [one-carbon compound](http://purl.obolibrary.org/obo/CHEBI_64708) SubClassOf [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) + + + +### one-carbon compound transport `http://purl.obolibrary.org/obo/GO_0019755` +#### Removed +- [one-carbon compound transport](http://purl.obolibrary.org/obo/GO_0019755) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [one-carbon compound transport](http://purl.obolibrary.org/obo/GO_0019755) [label](http://www.w3.org/2000/01/rdf-schema#label) "one-carbon compound transport" + +- [one-carbon compound transport](http://purl.obolibrary.org/obo/GO_0019755) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0019755" + +- [one-carbon compound transport](http://purl.obolibrary.org/obo/GO_0019755) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "one carbon compound transport" + +- [one-carbon compound transport](http://purl.obolibrary.org/obo/GO_0019755) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- Class: [one-carbon compound transport](http://purl.obolibrary.org/obo/GO_0019755) + +- [one-carbon compound transport](http://purl.obolibrary.org/obo/GO_0019755) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [one-carbon compound](http://purl.obolibrary.org/obo/CHEBI_64708)) + +- [one-carbon compound transport](http://purl.obolibrary.org/obo/GO_0019755) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [one-carbon compound](http://purl.obolibrary.org/obo/CHEBI_64708) + +- [one-carbon compound transport](http://purl.obolibrary.org/obo/GO_0019755) SubClassOf [organic substance transport](http://purl.obolibrary.org/obo/GO_0071702) + + + +### onium cation `http://purl.obolibrary.org/obo/CHEBI_50313` +#### Removed +- [onium cation](http://purl.obolibrary.org/obo/CHEBI_50313) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "onium cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [onium cation](http://purl.obolibrary.org/obo/CHEBI_50313) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "onium cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [onium cation](http://purl.obolibrary.org/obo/CHEBI_50313) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50313" + +- [onium cation](http://purl.obolibrary.org/obo/CHEBI_50313) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [onium cation](http://purl.obolibrary.org/obo/CHEBI_50313) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "onium ions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [onium cation](http://purl.obolibrary.org/obo/CHEBI_50313) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families." + +- [onium cation](http://purl.obolibrary.org/obo/CHEBI_50313) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "onium ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [onium cation](http://purl.obolibrary.org/obo/CHEBI_50313) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [onium cation](http://purl.obolibrary.org/obo/CHEBI_50313) [label](http://www.w3.org/2000/01/rdf-schema#label) "onium cation" + +- Class: [onium cation](http://purl.obolibrary.org/obo/CHEBI_50313) + +- [onium cation](http://purl.obolibrary.org/obo/CHEBI_50313) SubClassOf [onium compound](http://purl.obolibrary.org/obo/CHEBI_50312) + + + +### onium compound `http://purl.obolibrary.org/obo/CHEBI_50312` +#### Removed +- [onium compound](http://purl.obolibrary.org/obo/CHEBI_50312) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50312" + +- [onium compound](http://purl.obolibrary.org/obo/CHEBI_50312) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#1_STAR) + +- [onium compound](http://purl.obolibrary.org/obo/CHEBI_50312) [label](http://www.w3.org/2000/01/rdf-schema#label) "onium compound" + +- [onium compound](http://purl.obolibrary.org/obo/CHEBI_50312) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [onium compound](http://purl.obolibrary.org/obo/CHEBI_50312) + +- [onium compound](http://purl.obolibrary.org/obo/CHEBI_50312) SubClassOf [heteroatomic molecular entity](http://purl.obolibrary.org/obo/CHEBI_37577) + + + +### only in taxon `http://purl.obolibrary.org/obo/RO_0002160` +#### Removed +- [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall"@en + +#### Added +- [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### organic acid `http://purl.obolibrary.org/obo/CHEBI_64709` +#### Removed +- [organic acid](http://purl.obolibrary.org/obo/CHEBI_64709) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic acid](http://purl.obolibrary.org/obo/CHEBI_64709) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic acid" + +- [organic acid](http://purl.obolibrary.org/obo/CHEBI_64709) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:64709" + +- [organic acid](http://purl.obolibrary.org/obo/CHEBI_64709) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organic acid](http://purl.obolibrary.org/obo/CHEBI_64709) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic acid](http://purl.obolibrary.org/obo/CHEBI_64709) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any organic molecular entity that is acidic and contains carbon in covalent linkage." + +- [organic acid](http://purl.obolibrary.org/obo/CHEBI_64709) SubClassOf [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) + + + +### organic acid catabolic process `http://purl.obolibrary.org/obo/GO_0016054` +#### Removed +- [organic acid catabolic process](http://purl.obolibrary.org/obo/GO_0016054) SubClassOf [organic substance catabolic process](http://purl.obolibrary.org/obo/GO_1901575) + + + +### organic acid transport `http://purl.obolibrary.org/obo/GO_0015849` +#### Removed +- [organic acid transport](http://purl.obolibrary.org/obo/GO_0015849) SubClassOf [organic substance transport](http://purl.obolibrary.org/obo/GO_0071702) + +#### Added +- [organic acid transport](http://purl.obolibrary.org/obo/GO_0015849) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### organic amino compound `http://purl.obolibrary.org/obo/CHEBI_50047` +#### Removed +- [organic amino compound](http://purl.obolibrary.org/obo/CHEBI_50047) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic amino compound](http://purl.obolibrary.org/obo/CHEBI_50047) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic amino compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic amino compound](http://purl.obolibrary.org/obo/CHEBI_50047) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic amino compound" + +- [organic amino compound](http://purl.obolibrary.org/obo/CHEBI_50047) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Bronsted base](http://purl.obolibrary.org/obo/CHEBI_39142) + +- [organic amino compound](http://purl.obolibrary.org/obo/CHEBI_50047) SubClassOf [has_parent_hydride](http://purl.obolibrary.org/obo/chebi#has_parent_hydride) some [ammonia](http://purl.obolibrary.org/obo/CHEBI_16134) + +- [organic amino compound](http://purl.obolibrary.org/obo/CHEBI_50047) SubClassOf [organonitrogen compound](http://purl.obolibrary.org/obo/CHEBI_35352) + + + +### organic anion `http://purl.obolibrary.org/obo/CHEBI_25696` +#### Removed +- [organic anion](http://purl.obolibrary.org/obo/CHEBI_25696) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic anion](http://purl.obolibrary.org/obo/CHEBI_25696) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25696" + +- [organic anion](http://purl.obolibrary.org/obo/CHEBI_25696) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic anion" + +- [organic anion](http://purl.obolibrary.org/obo/CHEBI_25696) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any organic ion with a net negative charge." + +- [organic anion](http://purl.obolibrary.org/obo/CHEBI_25696) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic anion](http://purl.obolibrary.org/obo/CHEBI_25696) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [organic anion](http://purl.obolibrary.org/obo/CHEBI_25696) + +- [organic anion](http://purl.obolibrary.org/obo/CHEBI_25696) SubClassOf [organic ion](http://purl.obolibrary.org/obo/CHEBI_25699) + +- [organic anion](http://purl.obolibrary.org/obo/CHEBI_25696) SubClassOf [anion](http://purl.obolibrary.org/obo/CHEBI_22563) + + + +### organic anion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0008514` +#### Removed +- [organic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008514) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [organic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008514) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-2142859" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "Growing HA is extruded from the cell by ABCC5" + +- [organic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008514) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0008514" + +- [organic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008514) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [organic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008514) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic anion transmembrane transporter activity" + +- Class: [organic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008514) + +- [organic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008514) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [organic anion](http://purl.obolibrary.org/obo/CHEBI_25696)) + +- [organic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008514) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [organic anion transport](http://purl.obolibrary.org/obo/GO_0015711) + +- [organic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008514) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [organic anion](http://purl.obolibrary.org/obo/CHEBI_25696) + +- [organic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008514) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + + +### organic anion transport `http://purl.obolibrary.org/obo/GO_0015711` +#### Removed +- [organic anion transport](http://purl.obolibrary.org/obo/GO_0015711) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic anion transport" + +- [organic anion transport](http://purl.obolibrary.org/obo/GO_0015711) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [organic anion transport](http://purl.obolibrary.org/obo/GO_0015711) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015711" + +- [organic anion transport](http://purl.obolibrary.org/obo/GO_0015711) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [organic anion transport](http://purl.obolibrary.org/obo/GO_0015711) + +- [organic anion transport](http://purl.obolibrary.org/obo/GO_0015711) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [organic anion](http://purl.obolibrary.org/obo/CHEBI_25696)) + +- [organic anion transport](http://purl.obolibrary.org/obo/GO_0015711) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [organic anion](http://purl.obolibrary.org/obo/CHEBI_25696) + +- [organic anion transport](http://purl.obolibrary.org/obo/GO_0015711) SubClassOf [organic substance transport](http://purl.obolibrary.org/obo/GO_0071702) + + + +### organic aromatic compound `http://purl.obolibrary.org/obo/CHEBI_33659` +#### Removed +- [organic aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33659) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic aromatic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [organic aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33659) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33659) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organic aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33659) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33659" + +- [organic aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33659) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic aromatic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33659) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic aromatic compound" + +- Class: [organic aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33659) + +- [organic aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33659) SubClassOf [aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33655) + +- [organic aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33659) SubClassOf [organic cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33832) + + + +### organic cation `http://purl.obolibrary.org/obo/CHEBI_25697` +#### Removed +- [organic cation](http://purl.obolibrary.org/obo/CHEBI_25697) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic cation" + +- [organic cation](http://purl.obolibrary.org/obo/CHEBI_25697) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organic cation](http://purl.obolibrary.org/obo/CHEBI_25697) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any organic ion with a net positive charge." + +- [organic cation](http://purl.obolibrary.org/obo/CHEBI_25697) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic cation](http://purl.obolibrary.org/obo/CHEBI_25697) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic cation](http://purl.obolibrary.org/obo/CHEBI_25697) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25697" + +- Class: [organic cation](http://purl.obolibrary.org/obo/CHEBI_25697) + +- [organic cation](http://purl.obolibrary.org/obo/CHEBI_25697) SubClassOf [organic ion](http://purl.obolibrary.org/obo/CHEBI_25699) + +- [organic cation](http://purl.obolibrary.org/obo/CHEBI_25697) SubClassOf [cation](http://purl.obolibrary.org/obo/CHEBI_36916) + + + +### organic cation transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015101` +#### Removed +- [organic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015101) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-549322" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "OCT1 transports organic cations out of hepatic cells" + +- [organic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015101) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-561072" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "OCT3 mediates renal uptake of organic cations" + +- [organic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015101) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015101" + +- [organic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015101) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-549279" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "OCT2 mediates tubular uptake of organic cations in the kidney" + +- [organic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015101) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic cation transmembrane transporter activity" + +- [organic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015101) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-549129" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "OCT1 transports organic cations into hepatic cells" + +- [organic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015101) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-561054" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "OCT2 mediates tubular secretion of organic cations in the kidney" + +- [organic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015101) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [organic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015101) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0815340729" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_transport" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [organic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015101) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-549304" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "OCT3 mediates renal clearance of organic cations" + +- [organic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015101) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-2161500" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "abacavir [extracellular] => abacavir [cytosol]" + +- Class: [organic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015101) + +- [organic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015101) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [organic cation](http://purl.obolibrary.org/obo/CHEBI_25697)) + +- [organic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015101) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [organic cation](http://purl.obolibrary.org/obo/CHEBI_25697) + +- [organic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015101) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + +- [organic cation transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015101) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [organic cation transport](http://purl.obolibrary.org/obo/GO_0015695) + + + +### organic cation transport `http://purl.obolibrary.org/obo/GO_0015695` +#### Removed +- [organic cation transport](http://purl.obolibrary.org/obo/GO_0015695) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [organic cation transport](http://purl.obolibrary.org/obo/GO_0015695) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic cation transport" + +- [organic cation transport](http://purl.obolibrary.org/obo/GO_0015695) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015695" + +- [organic cation transport](http://purl.obolibrary.org/obo/GO_0015695) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [organic cation transport](http://purl.obolibrary.org/obo/GO_0015695) + +- [organic cation transport](http://purl.obolibrary.org/obo/GO_0015695) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [organic cation](http://purl.obolibrary.org/obo/CHEBI_25697)) + +- [organic cation transport](http://purl.obolibrary.org/obo/GO_0015695) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [organic cation](http://purl.obolibrary.org/obo/CHEBI_25697) + +- [organic cation transport](http://purl.obolibrary.org/obo/GO_0015695) SubClassOf [organic substance transport](http://purl.obolibrary.org/obo/GO_0071702) + + + +### organic cyclic compound `http://purl.obolibrary.org/obo/CHEBI_33832` +#### Removed +- [organic cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33832) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any organic molecule that consists of atoms connected in the form of a ring." + +- [organic cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33832) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic cyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33832) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic cyclic compound" + +- [organic cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33832) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33832) SubClassOf [cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33595) + +- [organic cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33832) SubClassOf [organic molecule](http://purl.obolibrary.org/obo/CHEBI_72695) + + + +### organic cyclic compound catabolic process `http://purl.obolibrary.org/obo/GO_1901361` +#### Removed +- [organic cyclic compound catabolic process](http://purl.obolibrary.org/obo/GO_1901361) SubClassOf [organic substance catabolic process](http://purl.obolibrary.org/obo/GO_1901575) + +#### Added +- [organic cyclic compound catabolic process](http://purl.obolibrary.org/obo/GO_1901361) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### organic divalent group `http://purl.obolibrary.org/obo/CHEBI_51446` +#### Removed +- [organic divalent group](http://purl.obolibrary.org/obo/CHEBI_51446) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organic divalent group](http://purl.obolibrary.org/obo/CHEBI_51446) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#1_STAR) + +- [organic divalent group](http://purl.obolibrary.org/obo/CHEBI_51446) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic divalent group" + +- [organic divalent group](http://purl.obolibrary.org/obo/CHEBI_51446) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:51446" + +- Class: [organic divalent group](http://purl.obolibrary.org/obo/CHEBI_51446) + +- [organic divalent group](http://purl.obolibrary.org/obo/CHEBI_51446) SubClassOf [organic group](http://purl.obolibrary.org/obo/CHEBI_33247) + + + +### organic fundamental parent `http://purl.obolibrary.org/obo/CHEBI_33245` +#### Removed +- [organic fundamental parent](http://purl.obolibrary.org/obo/CHEBI_33245) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic fundamental parent](http://purl.obolibrary.org/obo/CHEBI_33245) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33245" + +- [organic fundamental parent](http://purl.obolibrary.org/obo/CHEBI_33245) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organic fundamental parent](http://purl.obolibrary.org/obo/CHEBI_33245) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic fundamental parent" + +- [organic fundamental parent](http://purl.obolibrary.org/obo/CHEBI_33245) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic fundamental parents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic fundamental parent](http://purl.obolibrary.org/obo/CHEBI_33245) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system." + +- [organic fundamental parent](http://purl.obolibrary.org/obo/CHEBI_33245) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic parent hydrides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [organic fundamental parent](http://purl.obolibrary.org/obo/CHEBI_33245) + +- [organic fundamental parent](http://purl.obolibrary.org/obo/CHEBI_33245) SubClassOf [organic hydride](http://purl.obolibrary.org/obo/CHEBI_37175) + +- [organic fundamental parent](http://purl.obolibrary.org/obo/CHEBI_33245) SubClassOf [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) + + + +### organic group `http://purl.obolibrary.org/obo/CHEBI_33247` +#### Removed +- [organic group](http://purl.obolibrary.org/obo/CHEBI_33247) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic groups" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic group](http://purl.obolibrary.org/obo/CHEBI_33247) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic group](http://purl.obolibrary.org/obo/CHEBI_33247) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organic group](http://purl.obolibrary.org/obo/CHEBI_33247) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any substituent group or skeleton containing carbon." + +- [organic group](http://purl.obolibrary.org/obo/CHEBI_33247) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic group" + +- [organic group](http://purl.obolibrary.org/obo/CHEBI_33247) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33247" + +- Class: [organic group](http://purl.obolibrary.org/obo/CHEBI_33247) + +- [organic group](http://purl.obolibrary.org/obo/CHEBI_33247) SubClassOf [group](http://purl.obolibrary.org/obo/CHEBI_24433) + +- [organic group](http://purl.obolibrary.org/obo/CHEBI_33247) SubClassOf [is_substituent_group_from](http://purl.obolibrary.org/obo/chebi#is_substituent_group_from) some [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) + + + +### organic heterobicyclic compound `http://purl.obolibrary.org/obo/CHEBI_27171` +#### Removed +- [organic heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_27171) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_27171) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic heterobicyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_27171) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:27171" + +- [organic heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_27171) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organic heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_27171) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic heterobicyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [organic heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_27171) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "heterobicyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [organic heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_27171) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic heterobicyclic compound" + +- [organic heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_27171) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "heterobicyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [organic heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_27171) + +- [organic heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_27171) SubClassOf [organic heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_38166) + +- [organic heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_27171) SubClassOf [heterobicyclic compound](http://purl.obolibrary.org/obo/CHEBI_33672) + + + +### organic heterobicyclic ring `http://purl.obolibrary.org/obo/CHEBI_73541` +#### Removed +- [organic heterobicyclic ring](http://purl.obolibrary.org/obo/CHEBI_73541) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic heterobicyclic ring" + +- [organic heterobicyclic ring](http://purl.obolibrary.org/obo/CHEBI_73541) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic heterobicyclic rings" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic heterobicyclic ring](http://purl.obolibrary.org/obo/CHEBI_73541) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A bicyclic organic group that contains both carbon and hetero atoms." + +- [organic heterobicyclic ring](http://purl.obolibrary.org/obo/CHEBI_73541) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic heterobicyclic ring](http://purl.obolibrary.org/obo/CHEBI_73541) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:73541" + +- [organic heterobicyclic ring](http://purl.obolibrary.org/obo/CHEBI_73541) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [organic heterobicyclic ring](http://purl.obolibrary.org/obo/CHEBI_73541) + +- [organic heterobicyclic ring](http://purl.obolibrary.org/obo/CHEBI_73541) SubClassOf [cyclic organic group](http://purl.obolibrary.org/obo/CHEBI_52845) + + + +### organic heterocyclic compound `http://purl.obolibrary.org/obo/CHEBI_24532` +#### Removed +- [organic heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_24532) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_24532) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic heterocycle" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_24532) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic heterocyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [organic heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_24532) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24532" + +- [organic heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_24532) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A cyclic compound having as ring members atoms of carbon and at least of one other element." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [organic heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_24532) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic heterocyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_24532) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic heterocycle" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [organic heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_24532) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic heterocyclic compound" + +- [organic heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_24532) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [organic heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_24532) + +- [organic heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_24532) SubClassOf [organic cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33832) + +- [organic heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_24532) SubClassOf [heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_5686) + +- [organic heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_24532) SubClassOf [heteroorganic entity](http://purl.obolibrary.org/obo/CHEBI_33285) + + + +### organic heteropolycyclic compound `http://purl.obolibrary.org/obo/CHEBI_38166` +#### Removed +- [organic heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_38166) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:38075" + +- [organic heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_38166) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic heteropolycyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_38166) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_38166) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic heteropolycyclic compound" + +- [organic heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_38166) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:38166" + +- [organic heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_38166) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organic heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_38166) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:25429" + +- Class: [organic heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_38166) + +- [organic heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_38166) SubClassOf [organic heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_24532) + +- [organic heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_38166) SubClassOf [heteropolycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33671) + + + +### organic hydride `http://purl.obolibrary.org/obo/CHEBI_37175` +#### Removed +- [organic hydride](http://purl.obolibrary.org/obo/CHEBI_37175) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organic hydride](http://purl.obolibrary.org/obo/CHEBI_37175) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic hydrides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic hydride](http://purl.obolibrary.org/obo/CHEBI_37175) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic hydride](http://purl.obolibrary.org/obo/CHEBI_37175) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic hydride" + +- [organic hydride](http://purl.obolibrary.org/obo/CHEBI_37175) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:37175" + +- Class: [organic hydride](http://purl.obolibrary.org/obo/CHEBI_37175) + +- [organic hydride](http://purl.obolibrary.org/obo/CHEBI_37175) SubClassOf [hydrides](http://purl.obolibrary.org/obo/CHEBI_33692) + + + +### organic hydroxy compound `http://purl.obolibrary.org/obo/CHEBI_33822` +#### Removed +- [organic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_33822) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydroxy compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [organic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_33822) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_33822) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic hydroxy compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_33822) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:64710" + +- [organic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_33822) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic hydroxy compound" + +- [organic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_33822) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_33822) SubClassOf [hydroxides](http://purl.obolibrary.org/obo/CHEBI_24651) + +- [organic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_33822) SubClassOf [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) + + + +### organic hydroxy compound catabolic process `http://purl.obolibrary.org/obo/GO_1901616` +#### Removed +- [organic hydroxy compound catabolic process](http://purl.obolibrary.org/obo/GO_1901616) SubClassOf [organic substance catabolic process](http://purl.obolibrary.org/obo/GO_1901575) + +#### Added +- [organic hydroxy compound catabolic process](http://purl.obolibrary.org/obo/GO_1901616) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### organic ion `http://purl.obolibrary.org/obo/CHEBI_25699` +#### Removed +- [organic ion](http://purl.obolibrary.org/obo/CHEBI_25699) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25699" + +- [organic ion](http://purl.obolibrary.org/obo/CHEBI_25699) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organic ion](http://purl.obolibrary.org/obo/CHEBI_25699) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic ion" + +- [organic ion](http://purl.obolibrary.org/obo/CHEBI_25699) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic ion](http://purl.obolibrary.org/obo/CHEBI_25699) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic ions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [organic ion](http://purl.obolibrary.org/obo/CHEBI_25699) + +- [organic ion](http://purl.obolibrary.org/obo/CHEBI_25699) SubClassOf [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) + +- [organic ion](http://purl.obolibrary.org/obo/CHEBI_25699) SubClassOf [ion](http://purl.obolibrary.org/obo/CHEBI_24870) + + + +### organic molecular entity `http://purl.obolibrary.org/obo/CHEBI_50860` +#### Removed +- [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:33244" + +- [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:25700" + +- [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic molecular entity" + +- [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) SubClassOf [carbon group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33582) + +- [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [carbon atom](http://purl.obolibrary.org/obo/CHEBI_27594) + + + +### organic molecule `http://purl.obolibrary.org/obo/CHEBI_72695` +#### Removed +- [organic molecule](http://purl.obolibrary.org/obo/CHEBI_72695) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity." + +- [organic molecule](http://purl.obolibrary.org/obo/CHEBI_72695) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic compound" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic molecule](http://purl.obolibrary.org/obo/CHEBI_72695) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic molecule](http://purl.obolibrary.org/obo/CHEBI_72695) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic molecule](http://purl.obolibrary.org/obo/CHEBI_72695) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic molecule" + +- [organic molecule](http://purl.obolibrary.org/obo/CHEBI_72695) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:72695" + +- [organic molecule](http://purl.obolibrary.org/obo/CHEBI_72695) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic molecules" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic molecule](http://purl.obolibrary.org/obo/CHEBI_72695) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [organic molecule](http://purl.obolibrary.org/obo/CHEBI_72695) + +- [organic molecule](http://purl.obolibrary.org/obo/CHEBI_72695) SubClassOf [organic molecular entity](http://purl.obolibrary.org/obo/CHEBI_50860) + +- [organic molecule](http://purl.obolibrary.org/obo/CHEBI_72695) SubClassOf [molecule](http://purl.obolibrary.org/obo/CHEBI_25367) + + + +### organic oxo compound `http://purl.obolibrary.org/obo/CHEBI_36587` +#### Removed +- [organic oxo compound](http://purl.obolibrary.org/obo/CHEBI_36587) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic oxo compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [organic oxo compound](http://purl.obolibrary.org/obo/CHEBI_36587) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic oxo compound" + +- [organic oxo compound](http://purl.obolibrary.org/obo/CHEBI_36587) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxo compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [organic oxo compound](http://purl.obolibrary.org/obo/CHEBI_36587) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organic oxo compound](http://purl.obolibrary.org/obo/CHEBI_36587) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36587" + +- [organic oxo compound](http://purl.obolibrary.org/obo/CHEBI_36587) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxo compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [organic oxo compound](http://purl.obolibrary.org/obo/CHEBI_36587) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [organic oxo compound](http://purl.obolibrary.org/obo/CHEBI_36587) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic oxo compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic oxo compound](http://purl.obolibrary.org/obo/CHEBI_36587) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [organic oxo compound](http://purl.obolibrary.org/obo/CHEBI_36587) + +- [organic oxo compound](http://purl.obolibrary.org/obo/CHEBI_36587) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) + +- [organic oxo compound](http://purl.obolibrary.org/obo/CHEBI_36587) SubClassOf [organic molecule](http://purl.obolibrary.org/obo/CHEBI_72695) + + + +### organic polycyclic compound `http://purl.obolibrary.org/obo/CHEBI_51958` +#### Removed +- [organic polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_51958) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_51958) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic polycyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_51958) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic polycyclic compound" + +- [organic polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_51958) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:51958" + +- [organic polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_51958) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [organic polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_51958) + +- [organic polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_51958) SubClassOf [organic cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33832) + +- [organic polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_51958) SubClassOf [polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33635) + + + +### organic salt `http://purl.obolibrary.org/obo/CHEBI_24868` +#### Removed +- [organic salt](http://purl.obolibrary.org/obo/CHEBI_24868) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic salt](http://purl.obolibrary.org/obo/CHEBI_24868) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24868" + +- [organic salt](http://purl.obolibrary.org/obo/CHEBI_24868) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organic salt](http://purl.obolibrary.org/obo/CHEBI_24868) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic salts" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic salt](http://purl.obolibrary.org/obo/CHEBI_24868) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic salt" + +- [organic salt](http://purl.obolibrary.org/obo/CHEBI_24868) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organisches Salz" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [organic salt](http://purl.obolibrary.org/obo/CHEBI_24868) + +- [organic salt](http://purl.obolibrary.org/obo/CHEBI_24868) SubClassOf [salt](http://purl.obolibrary.org/obo/CHEBI_24866) + + + +### organic sodium salt `http://purl.obolibrary.org/obo/CHEBI_38700` +#### Removed +- [organic sodium salt](http://purl.obolibrary.org/obo/CHEBI_38700) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic sodium salt](http://purl.obolibrary.org/obo/CHEBI_38700) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic sodium salt" + +- [organic sodium salt](http://purl.obolibrary.org/obo/CHEBI_38700) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic sodium salts" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic sodium salt](http://purl.obolibrary.org/obo/CHEBI_38700) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:38700" + +- [organic sodium salt](http://purl.obolibrary.org/obo/CHEBI_38700) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organic sodium salt](http://purl.obolibrary.org/obo/CHEBI_38700) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organic sodium salt" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [organic sodium salt](http://purl.obolibrary.org/obo/CHEBI_38700) + +- [organic sodium salt](http://purl.obolibrary.org/obo/CHEBI_38700) SubClassOf [organic salt](http://purl.obolibrary.org/obo/CHEBI_24868) + +- [organic sodium salt](http://purl.obolibrary.org/obo/CHEBI_38700) SubClassOf [sodium salt](http://purl.obolibrary.org/obo/CHEBI_26714) + + + +### organic sulfate `http://purl.obolibrary.org/obo/CHEBI_25704` +#### Removed +- [organic sulfate](http://purl.obolibrary.org/obo/CHEBI_25704) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic sulfate" + +- [organic sulfate](http://purl.obolibrary.org/obo/CHEBI_25704) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25704" + +- [organic sulfate](http://purl.obolibrary.org/obo/CHEBI_25704) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Compounds of the general formula SO3HOR where R is an organyl group" + +- [organic sulfate](http://purl.obolibrary.org/obo/CHEBI_25704) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organic sulfates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organic sulfate](http://purl.obolibrary.org/obo/CHEBI_25704) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organic sulfate](http://purl.obolibrary.org/obo/CHEBI_25704) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [organic sulfate](http://purl.obolibrary.org/obo/CHEBI_25704) + +- [organic sulfate](http://purl.obolibrary.org/obo/CHEBI_25704) SubClassOf [sulfates](http://purl.obolibrary.org/obo/CHEBI_26820) + +- [organic sulfate](http://purl.obolibrary.org/obo/CHEBI_25704) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [organosulfate oxoanion](http://purl.obolibrary.org/obo/CHEBI_58958) + + + +### organic univalent group `http://purl.obolibrary.org/obo/CHEBI_51447` +#### Removed +- [organic univalent group](http://purl.obolibrary.org/obo/CHEBI_51447) [label](http://www.w3.org/2000/01/rdf-schema#label) "organic univalent group" + +- [organic univalent group](http://purl.obolibrary.org/obo/CHEBI_51447) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organic univalent group](http://purl.obolibrary.org/obo/CHEBI_51447) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#1_STAR) + +- [organic univalent group](http://purl.obolibrary.org/obo/CHEBI_51447) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:51447" + +- Class: [organic univalent group](http://purl.obolibrary.org/obo/CHEBI_51447) + +- [organic univalent group](http://purl.obolibrary.org/obo/CHEBI_51447) SubClassOf [organic group](http://purl.obolibrary.org/obo/CHEBI_33247) + + + +### organism `http://purl.obolibrary.org/obo/CARO_0001010` +#### Removed +- [organism](http://purl.obolibrary.org/obo/CARO_0001010) [label](http://www.w3.org/2000/01/rdf-schema#label) "organism or virus or viroid" + +#### Added +- [organism](http://purl.obolibrary.org/obo/CARO_0001010) [label](http://www.w3.org/2000/01/rdf-schema#label) "organism" + +- [organism](http://purl.obolibrary.org/obo/CARO_0001010) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organism or virus or viroid" + + +### organochalcogen compound `http://purl.obolibrary.org/obo/CHEBI_36962` +#### Removed +- [organochalcogen compound](http://purl.obolibrary.org/obo/CHEBI_36962) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organochalcogen compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [organochalcogen compound](http://purl.obolibrary.org/obo/CHEBI_36962) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organochalcogen compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organochalcogen compound](http://purl.obolibrary.org/obo/CHEBI_36962) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organochalcogen compound](http://purl.obolibrary.org/obo/CHEBI_36962) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organochalcogen compound" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [organochalcogen compound](http://purl.obolibrary.org/obo/CHEBI_36962) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36962" + +- [organochalcogen compound](http://purl.obolibrary.org/obo/CHEBI_36962) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organochalcogen compound](http://purl.obolibrary.org/obo/CHEBI_36962) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organochalcogen compound" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organochalcogen compound](http://purl.obolibrary.org/obo/CHEBI_36962) [label](http://www.w3.org/2000/01/rdf-schema#label) "organochalcogen compound" + +- [organochalcogen compound](http://purl.obolibrary.org/obo/CHEBI_36962) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An organochalcogen compound is a compound containing at least one carbon-chalcogen bond." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- Class: [organochalcogen compound](http://purl.obolibrary.org/obo/CHEBI_36962) + +- [organochalcogen compound](http://purl.obolibrary.org/obo/CHEBI_36962) SubClassOf [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) + +- [organochalcogen compound](http://purl.obolibrary.org/obo/CHEBI_36962) SubClassOf [heteroorganic entity](http://purl.obolibrary.org/obo/CHEBI_33285) + + + +### organodiyl group `http://purl.obolibrary.org/obo/CHEBI_51422` +#### Removed +- [organodiyl group](http://purl.obolibrary.org/obo/CHEBI_51422) [label](http://www.w3.org/2000/01/rdf-schema#label) "organodiyl group" + +- [organodiyl group](http://purl.obolibrary.org/obo/CHEBI_51422) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s)." + +- [organodiyl group](http://purl.obolibrary.org/obo/CHEBI_51422) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organodiyl group](http://purl.obolibrary.org/obo/CHEBI_51422) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:51422" + +- [organodiyl group](http://purl.obolibrary.org/obo/CHEBI_51422) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organodiyl group](http://purl.obolibrary.org/obo/CHEBI_51422) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organodiyl groups" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [organodiyl group](http://purl.obolibrary.org/obo/CHEBI_51422) + +- [organodiyl group](http://purl.obolibrary.org/obo/CHEBI_51422) SubClassOf [organic divalent group](http://purl.obolibrary.org/obo/CHEBI_51446) + + + +### organonitrogen compound `http://purl.obolibrary.org/obo/CHEBI_35352` +#### Removed +- [organonitrogen compound](http://purl.obolibrary.org/obo/CHEBI_35352) [label](http://www.w3.org/2000/01/rdf-schema#label) "organonitrogen compound" + +- [organonitrogen compound](http://purl.obolibrary.org/obo/CHEBI_35352) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organonitrogens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organonitrogen compound](http://purl.obolibrary.org/obo/CHEBI_35352) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organonitrogen compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [organonitrogen compound](http://purl.obolibrary.org/obo/CHEBI_35352) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organonitrogen compound](http://purl.obolibrary.org/obo/CHEBI_35352) SubClassOf [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) + +- [organonitrogen compound](http://purl.obolibrary.org/obo/CHEBI_35352) SubClassOf [heteroorganic entity](http://purl.obolibrary.org/obo/CHEBI_33285) + + + +### organonitrogen compound catabolic process `http://purl.obolibrary.org/obo/GO_1901565` +#### Removed +- [organonitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_1901565) SubClassOf [organic substance catabolic process](http://purl.obolibrary.org/obo/GO_1901575) + +#### Added +- [organonitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_1901565) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### organonitrogen heterocyclic compound `http://purl.obolibrary.org/obo/CHEBI_38101` +#### Removed +- [organonitrogen heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_38101) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organonitrogen heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_38101) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organonitrogen heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_38101) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organonitrogen heterocyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organonitrogen heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_38101) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organonitrogen heterocyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [organonitrogen heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_38101) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "heterocyclic organonitrogen compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [organonitrogen heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_38101) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [organonitrogen heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_38101) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "heterocyclic organonitrogen compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organonitrogen heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_38101) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:38101" + +- [organonitrogen heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_38101) [label](http://www.w3.org/2000/01/rdf-schema#label) "organonitrogen heterocyclic compound" + +- Class: [organonitrogen heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_38101) + +- [organonitrogen heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_38101) SubClassOf [organic heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_24532) + +- [organonitrogen heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_38101) SubClassOf [organonitrogen compound](http://purl.obolibrary.org/obo/CHEBI_35352) + + + +### organooxygen compound `http://purl.obolibrary.org/obo/CHEBI_36963` +#### Removed +- [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organooxygen compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organooxygen compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17586126" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36963" + +- [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An organochalcogen compound containing at least one carbon-oxygen bond." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organooxygen compound" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) [label](http://www.w3.org/2000/01/rdf-schema#label) "organooxygen compound" + +- [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organooxygen compound" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) + +- [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) SubClassOf [organochalcogen compound](http://purl.obolibrary.org/obo/CHEBI_36962) + +- [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) SubClassOf [oxygen molecular entity](http://purl.obolibrary.org/obo/CHEBI_25806) + + + +### organosulfate oxoanion `http://purl.obolibrary.org/obo/CHEBI_58958` +#### Removed +- [organosulfate oxoanion](http://purl.obolibrary.org/obo/CHEBI_58958) [mass](http://purl.obolibrary.org/obo/chebi/mass) "96.06300" + +- [organosulfate oxoanion](http://purl.obolibrary.org/obo/CHEBI_58958) [label](http://www.w3.org/2000/01/rdf-schema#label) "organosulfate oxoanion" + +- [organosulfate oxoanion](http://purl.obolibrary.org/obo/CHEBI_58958) [formula](http://purl.obolibrary.org/obo/chebi/formula) "O4SR" + +- [organosulfate oxoanion](http://purl.obolibrary.org/obo/CHEBI_58958) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organosulfate oxoanion](http://purl.obolibrary.org/obo/CHEBI_58958) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organosulfate oxoanion](http://purl.obolibrary.org/obo/CHEBI_58958) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "95.95173" + +- [organosulfate oxoanion](http://purl.obolibrary.org/obo/CHEBI_58958) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[O-]S(=O)(=O)O[*]" + +- [organosulfate oxoanion](http://purl.obolibrary.org/obo/CHEBI_58958) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An organic anion of general formula RS(=O)2O(-) where R is an organyl group." + +- [organosulfate oxoanion](http://purl.obolibrary.org/obo/CHEBI_58958) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:58958" + +- [organosulfate oxoanion](http://purl.obolibrary.org/obo/CHEBI_58958) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organosulfate oxoanions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [organosulfate oxoanion](http://purl.obolibrary.org/obo/CHEBI_58958) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- Class: [organosulfate oxoanion](http://purl.obolibrary.org/obo/CHEBI_58958) + +- [organosulfate oxoanion](http://purl.obolibrary.org/obo/CHEBI_58958) SubClassOf [organic anion](http://purl.obolibrary.org/obo/CHEBI_25696) + +- [organosulfate oxoanion](http://purl.obolibrary.org/obo/CHEBI_58958) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [organic sulfate](http://purl.obolibrary.org/obo/CHEBI_25704) + +- [organosulfate oxoanion](http://purl.obolibrary.org/obo/CHEBI_58958) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) + +- [organosulfate oxoanion](http://purl.obolibrary.org/obo/CHEBI_58958) SubClassOf [sulfur oxoanion](http://purl.obolibrary.org/obo/CHEBI_33482) + + + +### organyl group `http://purl.obolibrary.org/obo/CHEBI_33249` +#### Removed +- [organyl group](http://purl.obolibrary.org/obo/CHEBI_33249) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organyl group" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [organyl group](http://purl.obolibrary.org/obo/CHEBI_33249) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "grupos organilo" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [organyl group](http://purl.obolibrary.org/obo/CHEBI_33249) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organyl groups" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [organyl group](http://purl.obolibrary.org/obo/CHEBI_33249) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "grupo organilo" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [organyl group](http://purl.obolibrary.org/obo/CHEBI_33249) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "groupe organyle" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [organyl group](http://purl.obolibrary.org/obo/CHEBI_33249) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any organic substituent group, regardless of functional type, having one free valence at a carbon atom." + +- [organyl group](http://purl.obolibrary.org/obo/CHEBI_33249) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [organyl group](http://purl.obolibrary.org/obo/CHEBI_33249) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [organyl group](http://purl.obolibrary.org/obo/CHEBI_33249) [label](http://www.w3.org/2000/01/rdf-schema#label) "organyl group" + +- [organyl group](http://purl.obolibrary.org/obo/CHEBI_33249) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33249" + +- Class: [organyl group](http://purl.obolibrary.org/obo/CHEBI_33249) + +- [organyl group](http://purl.obolibrary.org/obo/CHEBI_33249) SubClassOf [organic univalent group](http://purl.obolibrary.org/obo/CHEBI_51447) + + + +### outer fibrous layer of perichondrium `http://purl.obolibrary.org/obo/UBERON_0008305` + +#### Added +- [outer fibrous layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008305) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The perichondrium consists of two separate layers: an outer fibrous layer and inner chondrogenic layer. The fibrous layer contains fibroblasts, which produce collagenous fibers." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:The_Free_Encyclopedia" + +- [outer fibrous layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008305) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0005091" + +- [outer fibrous layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008305) [label](http://www.w3.org/2000/01/rdf-schema#label) "outer fibrous layer of perichondrium" + +- [outer fibrous layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008305) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0008305" + +- [outer fibrous layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008305) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [outer fibrous layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008305) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:The_Free_Encyclopedia" + +- Class: [outer fibrous layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008305) + +- [outer fibrous layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008305) SubClassOf [connective tissue](http://purl.obolibrary.org/obo/UBERON_0002384) + +- [outer fibrous layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008305) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) + - [source](http://www.geneontology.org/formats/oboInOwl#source) "BTO" + + +### output of `http://purl.obolibrary.org/obo/RO_0002353` +#### Removed +- [output of](http://purl.obolibrary.org/obo/RO_0002353) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [output of](http://purl.obolibrary.org/obo/RO_0002353) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### ovarian follicle `http://purl.obolibrary.org/obo/UBERON_0001305` +#### Removed +- [ovarian follicle](http://purl.obolibrary.org/obo/UBERON_0001305) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + + + +### oxide `http://purl.obolibrary.org/obo/CHEBI_25741` +#### Removed +- [oxide](http://purl.obolibrary.org/obo/CHEBI_25741) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An oxide is a chemical compound of oxygen with other chemical elements." + +- [oxide](http://purl.obolibrary.org/obo/CHEBI_25741) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [oxide](http://purl.obolibrary.org/obo/CHEBI_25741) [label](http://www.w3.org/2000/01/rdf-schema#label) "oxide" + +- [oxide](http://purl.obolibrary.org/obo/CHEBI_25741) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxide](http://purl.obolibrary.org/obo/CHEBI_25741) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxide](http://purl.obolibrary.org/obo/CHEBI_25741) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [oxide](http://purl.obolibrary.org/obo/CHEBI_25741) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25741" + +- Class: [oxide](http://purl.obolibrary.org/obo/CHEBI_25741) + +- [oxide](http://purl.obolibrary.org/obo/CHEBI_25741) SubClassOf [heteroatomic molecular entity](http://purl.obolibrary.org/obo/CHEBI_37577) + +- [oxide](http://purl.obolibrary.org/obo/CHEBI_25741) SubClassOf [oxygen molecular entity](http://purl.obolibrary.org/obo/CHEBI_25806) + + + +### oxidising agent `http://purl.obolibrary.org/obo/CHEBI_63248` +#### Removed +- [oxidising agent](http://purl.obolibrary.org/obo/CHEBI_63248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxidising agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxidising agent](http://purl.obolibrary.org/obo/CHEBI_63248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxidisers" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxidising agent](http://purl.obolibrary.org/obo/CHEBI_63248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxidiser" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxidising agent](http://purl.obolibrary.org/obo/CHEBI_63248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxidants" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxidising agent](http://purl.obolibrary.org/obo/CHEBI_63248) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [oxidising agent](http://purl.obolibrary.org/obo/CHEBI_63248) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A substance that removes electrons from another reactant in a redox reaction." + +- [oxidising agent](http://purl.obolibrary.org/obo/CHEBI_63248) [label](http://www.w3.org/2000/01/rdf-schema#label) "oxidising agent" + +- [oxidising agent](http://purl.obolibrary.org/obo/CHEBI_63248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxidizer" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxidising agent](http://purl.obolibrary.org/obo/CHEBI_63248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxidizing agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxidising agent](http://purl.obolibrary.org/obo/CHEBI_63248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxidizing agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxidising agent](http://purl.obolibrary.org/obo/CHEBI_63248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxidant" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxidising agent](http://purl.obolibrary.org/obo/CHEBI_63248) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxidizers" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxidising agent](http://purl.obolibrary.org/obo/CHEBI_63248) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [oxidising agent](http://purl.obolibrary.org/obo/CHEBI_63248) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:63248" + +- Class: [oxidising agent](http://purl.obolibrary.org/obo/CHEBI_63248) + +- [oxidising agent](http://purl.obolibrary.org/obo/CHEBI_63248) SubClassOf [chemical role](http://purl.obolibrary.org/obo/CHEBI_51086) + + + +### oxo group `http://purl.obolibrary.org/obo/CHEBI_46629` +#### Removed +- [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) [label](http://www.w3.org/2000/01/rdf-schema#label) "oxo group" + +- [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "15.99491" + +- [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:46629" + +- [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) [mass](http://purl.obolibrary.org/obo/chebi/mass) "15.99940" + +- [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxo" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "OXO GROUP" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) [formula](http://purl.obolibrary.org/obo/chebi/formula) "O" + +- [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:O" + +- [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "=O" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:29353" + +- [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "O=*" + +- [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:44607" + +- [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) + +- [oxo group](http://purl.obolibrary.org/obo/CHEBI_46629) SubClassOf [inorganic group](http://purl.obolibrary.org/obo/CHEBI_33246) + + + +### oxo steroid `http://purl.obolibrary.org/obo/CHEBI_35789` +#### Removed +- [oxo steroid](http://purl.obolibrary.org/obo/CHEBI_35789) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [oxo steroid](http://purl.obolibrary.org/obo/CHEBI_35789) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "keto steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxo steroid](http://purl.obolibrary.org/obo/CHEBI_35789) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:25804" + +- [oxo steroid](http://purl.obolibrary.org/obo/CHEBI_35789) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxosteroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxo steroid](http://purl.obolibrary.org/obo/CHEBI_35789) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:24979" + +- [oxo steroid](http://purl.obolibrary.org/obo/CHEBI_35789) [label](http://www.w3.org/2000/01/rdf-schema#label) "oxo steroid" + +- [oxo steroid](http://purl.obolibrary.org/obo/CHEBI_35789) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [oxo steroid](http://purl.obolibrary.org/obo/CHEBI_35789) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxo steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxo steroid](http://purl.obolibrary.org/obo/CHEBI_35789) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ketosteroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxo steroid](http://purl.obolibrary.org/obo/CHEBI_35789) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35789" + +- Class: [oxo steroid](http://purl.obolibrary.org/obo/CHEBI_35789) + +- [oxo steroid](http://purl.obolibrary.org/obo/CHEBI_35789) SubClassOf [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) + +- [oxo steroid](http://purl.obolibrary.org/obo/CHEBI_35789) SubClassOf [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) + + + +### oxoacid `http://purl.obolibrary.org/obo/CHEBI_24833` +#### Removed +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24833" + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxy-acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxy-acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxo acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxoacids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxacids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxyacids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxiacids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxoacid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [label](http://www.w3.org/2000/01/rdf-schema#label) "oxoacid" + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxacids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxoacid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxyacids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxoacids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxo acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxiacids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- Class: [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Bronsted acid](http://purl.obolibrary.org/obo/CHEBI_39141) + +- [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) SubClassOf [hydroxides](http://purl.obolibrary.org/obo/CHEBI_24651) + + + +### oxoacid derivative `http://purl.obolibrary.org/obo/CHEBI_33241` +#### Removed +- [oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33241) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33241) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33241" + +- [oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33241) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33241) [label](http://www.w3.org/2000/01/rdf-schema#label) "oxoacid derivative" + +- [oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33241) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxoacid derivatives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33241) + +- [oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33241) SubClassOf [heteroatomic molecular entity](http://purl.obolibrary.org/obo/CHEBI_37577) + +- [oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33241) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) + + + +### oxoanion `http://purl.obolibrary.org/obo/CHEBI_35406` +#### Removed +- [oxoanion](http://purl.obolibrary.org/obo/CHEBI_35406) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen." + +- [oxoanion](http://purl.obolibrary.org/obo/CHEBI_35406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxoanion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxoanion](http://purl.obolibrary.org/obo/CHEBI_35406) [label](http://www.w3.org/2000/01/rdf-schema#label) "oxoanion" + +- [oxoanion](http://purl.obolibrary.org/obo/CHEBI_35406) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:33436" + +- [oxoanion](http://purl.obolibrary.org/obo/CHEBI_35406) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:33274" + +- [oxoanion](http://purl.obolibrary.org/obo/CHEBI_35406) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35406" + +- [oxoanion](http://purl.obolibrary.org/obo/CHEBI_35406) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [oxoanion](http://purl.obolibrary.org/obo/CHEBI_35406) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxoacid anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxoanion](http://purl.obolibrary.org/obo/CHEBI_35406) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [oxoanion](http://purl.obolibrary.org/obo/CHEBI_35406) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxoanions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxoanion](http://purl.obolibrary.org/obo/CHEBI_35406) SubClassOf [oxide](http://purl.obolibrary.org/obo/CHEBI_25741) + +- [oxoanion](http://purl.obolibrary.org/obo/CHEBI_35406) SubClassOf [polyatomic anion](http://purl.obolibrary.org/obo/CHEBI_33273) + + + +### oxonium `http://purl.obolibrary.org/obo/CHEBI_29412` +#### Removed +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MolBase:1646" + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "H3O(+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "19.01784" + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:13968-08-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [formula](http://purl.obolibrary.org/obo/chebi/formula) "H3O" + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[OH3](+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MolBase" + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+1" + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxidanium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "XLYOFNOQVPJJNP-UHFFFAOYSA-O" + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Hydronium ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H][O+]([H])[H]" + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:13968-08-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/H2O/h1H2/p+1" + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:29412" + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Hydronium cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [mass](http://purl.obolibrary.org/obo/chebi/mass) "19.02322" + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [label](http://www.w3.org/2000/01/rdf-schema#label) "oxonium" + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:141" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aquahydrogen(1+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "trihydridooxygen(1+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxonium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) SubClassOf [onium cation](http://purl.obolibrary.org/obo/CHEBI_50313) + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) SubClassOf [oxygen hydride](http://purl.obolibrary.org/obo/CHEBI_33693) + +- [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [water](http://purl.obolibrary.org/obo/CHEBI_15377) + + + +### oxygen accumulating cell `http://purl.obolibrary.org/obo/CL_0000329` +#### Removed +- [oxygen accumulating cell](http://purl.obolibrary.org/obo/CL_0000329) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### oxygen atom `http://purl.obolibrary.org/obo/CHEBI_25805` +#### Removed +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00007" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [label](http://www.w3.org/2000/01/rdf-schema#label) "oxygen atom" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxygen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WebElements:O" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "QVGXLLKOCUKJST-UHFFFAOYSA-N" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxygene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "15.99491" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Sauerstoff" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "O" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25805" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxygen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[O]" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/O" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [mass](http://purl.obolibrary.org/obo/chebi/mass) "15.99940" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxigeno" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [formula](http://purl.obolibrary.org/obo/chebi/formula) "O" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "8O" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [macronutrient](http://purl.obolibrary.org/obo/CHEBI_33937) + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) SubClassOf [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) + +- [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) SubClassOf [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) + + + +### oxygen hydride `http://purl.obolibrary.org/obo/CHEBI_33693` +#### Removed +- [oxygen hydride](http://purl.obolibrary.org/obo/CHEBI_33693) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrides of oxygen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxygen hydride](http://purl.obolibrary.org/obo/CHEBI_33693) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxygen hydrides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxygen hydride](http://purl.obolibrary.org/obo/CHEBI_33693) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxygen hydride" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxygen hydride](http://purl.obolibrary.org/obo/CHEBI_33693) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [oxygen hydride](http://purl.obolibrary.org/obo/CHEBI_33693) [label](http://www.w3.org/2000/01/rdf-schema#label) "oxygen hydride" + +- [oxygen hydride](http://purl.obolibrary.org/obo/CHEBI_33693) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33693" + +- [oxygen hydride](http://purl.obolibrary.org/obo/CHEBI_33693) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [oxygen hydride](http://purl.obolibrary.org/obo/CHEBI_33693) + +- [oxygen hydride](http://purl.obolibrary.org/obo/CHEBI_33693) SubClassOf [chalcogen hydride](http://purl.obolibrary.org/obo/CHEBI_36902) + + + +### oxygen molecular entity `http://purl.obolibrary.org/obo/CHEBI_25806` +#### Removed +- [oxygen molecular entity](http://purl.obolibrary.org/obo/CHEBI_25806) [label](http://www.w3.org/2000/01/rdf-schema#label) "oxygen molecular entity" + +- [oxygen molecular entity](http://purl.obolibrary.org/obo/CHEBI_25806) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxygen molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxygen molecular entity](http://purl.obolibrary.org/obo/CHEBI_25806) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [oxygen molecular entity](http://purl.obolibrary.org/obo/CHEBI_25806) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxygen molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxygen molecular entity](http://purl.obolibrary.org/obo/CHEBI_25806) SubClassOf [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) + +- [oxygen molecular entity](http://purl.obolibrary.org/obo/CHEBI_25806) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [oxygen atom](http://purl.obolibrary.org/obo/CHEBI_25805) + + + +### oxygen radical `http://purl.obolibrary.org/obo/CHEBI_61073` +#### Removed +- [oxygen radical](http://purl.obolibrary.org/obo/CHEBI_61073) [label](http://www.w3.org/2000/01/rdf-schema#label) "oxygen radical" + +- [oxygen radical](http://purl.obolibrary.org/obo/CHEBI_61073) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [oxygen radical](http://purl.obolibrary.org/obo/CHEBI_61073) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [oxygen radical](http://purl.obolibrary.org/obo/CHEBI_61073) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:61073" + +- [oxygen radical](http://purl.obolibrary.org/obo/CHEBI_61073) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxygen radicals" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxygen radical](http://purl.obolibrary.org/obo/CHEBI_61073) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An inorganic radical in which a free electron resides on one or more oxygen atoms of an oxygen species." + +- Class: [oxygen radical](http://purl.obolibrary.org/obo/CHEBI_61073) + +- [oxygen radical](http://purl.obolibrary.org/obo/CHEBI_61073) SubClassOf [inorganic radical](http://purl.obolibrary.org/obo/CHEBI_36871) + +- [oxygen radical](http://purl.obolibrary.org/obo/CHEBI_61073) SubClassOf [reactive oxygen species](http://purl.obolibrary.org/obo/CHEBI_26523) + + + +### oxyketone `http://purl.obolibrary.org/obo/CHEBI_52395` +#### Removed +- [oxyketone](http://purl.obolibrary.org/obo/CHEBI_52395) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxyketones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxyketone](http://purl.obolibrary.org/obo/CHEBI_52395) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A compound with the general formula R2C=O (R=/=H) where one or more of the R groups contains an oxy (-O-) group." + +- [oxyketone](http://purl.obolibrary.org/obo/CHEBI_52395) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [oxyketone](http://purl.obolibrary.org/obo/CHEBI_52395) [label](http://www.w3.org/2000/01/rdf-schema#label) "oxyketone" + +- [oxyketone](http://purl.obolibrary.org/obo/CHEBI_52395) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [oxyketone](http://purl.obolibrary.org/obo/CHEBI_52395) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:52395" + +- Class: [oxyketone](http://purl.obolibrary.org/obo/CHEBI_52395) + +- [oxyketone](http://purl.obolibrary.org/obo/CHEBI_52395) SubClassOf [ketone](http://purl.obolibrary.org/obo/CHEBI_17087) + + + +### oxytocic `http://purl.obolibrary.org/obo/CHEBI_36063` +#### Removed +- [oxytocic](http://purl.obolibrary.org/obo/CHEBI_36063) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxytocic agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxytocic](http://purl.obolibrary.org/obo/CHEBI_36063) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A drug that stimulates contraction of the myometrium. Oxytocics are used to induce labour, obstetric at term, to prevent or control postpartum or postabortion haemorrhage, and to assess foetal status in high risk pregnancies. They may also be used alone or with other drugs to induce abortions (abortifacients)." + +- [oxytocic](http://purl.obolibrary.org/obo/CHEBI_36063) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [oxytocic](http://purl.obolibrary.org/obo/CHEBI_36063) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "uterine stimulants" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxytocic](http://purl.obolibrary.org/obo/CHEBI_36063) [label](http://www.w3.org/2000/01/rdf-schema#label) "oxytocic" + +- [oxytocic](http://purl.obolibrary.org/obo/CHEBI_36063) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxytocic" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxytocic](http://purl.obolibrary.org/obo/CHEBI_36063) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxytocic drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [oxytocic](http://purl.obolibrary.org/obo/CHEBI_36063) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [oxytocic](http://purl.obolibrary.org/obo/CHEBI_36063) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36063" + +- Class: [oxytocic](http://purl.obolibrary.org/obo/CHEBI_36063) + +- [oxytocic](http://purl.obolibrary.org/obo/CHEBI_36063) SubClassOf [drug](http://purl.obolibrary.org/obo/CHEBI_23888) + + + +### oxytocin `http://purl.obolibrary.org/obo/CHEBI_7872` +#### Removed +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Patent:US2938891" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG that also acts as a neurotransmitter in the brain; the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary. Together with the neuropeptide vasopressin, it is believed to influence social cognition and behaviour." + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:33192340" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:7872" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10983343" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3-Isoleucine-8-leucine vasopressin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00746" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18593851" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "OXT" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Patent:US3076797" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H][C@]1(NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)[C@@H](C)CC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:50-56-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10949083" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10949750" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18988842" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D00089" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic(1-6)-disulfide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C43H66N12O12S2/c1-5-22(4)35-42(66)49-26(12-13-32(45)57)38(62)51-29(17-33(46)58)39(63)53-30(20-69-68-19-25(44)36(60)50-28(40(64)54-35)16-23-8-10-24(56)11-9-23)43(67)55-14-6-7-31(55)41(65)52-27(15-21(2)3)37(61)48-18-34(47)59/h8-11,21-22,25-31,35,56H,5-7,12-20,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,48,61)(H,49,66)(H,50,60)(H,51,62)(H,52,65)(H,53,63)(H,54,64)/t22-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32979349" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19104313" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C43H66N12O12S2" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10834934" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:3586108" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [mass](http://purl.obolibrary.org/obo/chebi/mass) "1007.18982" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32509991" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Syntocinon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [BRAND_NAME](http://purl.obolibrary.org/obo/chebi#BRAND_NAME) + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Oxytocin" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [label](http://www.w3.org/2000/01/rdf-schema#label) "oxytocin" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10027619" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxytocine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11134819" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "OT" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(1-Hemicystine)oxytocin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19369205" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25209411" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB00107" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ocytocin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Orasthin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [BRAND_NAME](http://purl.obolibrary.org/obo/chebi#BRAND_NAME) + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24706799" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Endopituitrina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Pitocin" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [BRAND_NAME](http://purl.obolibrary.org/obo/chebi#BRAND_NAME) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0002865" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "1006.43646" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32683141" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:13305558" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19482229" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxytocin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "XNOPRXBHLZRZKH-DSZYJQQASA-N" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15815422" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Oxytocin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Piton S" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [BRAND_NAME](http://purl.obolibrary.org/obo/chebi#BRAND_NAME) + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Syntocinon" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [BRAND_NAME](http://purl.obolibrary.org/obo/chebi#BRAND_NAME) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxitocina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:2042" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxytocinum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) SubClassOf [heterodetic cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_24533) + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [vasodilator agent](http://purl.obolibrary.org/obo/CHEBI_35620) + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) SubClassOf [peptide hormone](http://purl.obolibrary.org/obo/CHEBI_25905) + +- [oxytocin](http://purl.obolibrary.org/obo/CHEBI_7872) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [oxytocic](http://purl.obolibrary.org/obo/CHEBI_36063) + + + +### p-block element atom `http://purl.obolibrary.org/obo/CHEBI_33560` +#### Removed +- [p-block element atom](http://purl.obolibrary.org/obo/CHEBI_33560) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33560" + +- [p-block element atom](http://purl.obolibrary.org/obo/CHEBI_33560) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "p-block element" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [p-block element atom](http://purl.obolibrary.org/obo/CHEBI_33560) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [p-block element atom](http://purl.obolibrary.org/obo/CHEBI_33560) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "p-block elements" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [p-block element atom](http://purl.obolibrary.org/obo/CHEBI_33560) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any main group element atom belonging to the p-block of the periodic table." + +- [p-block element atom](http://purl.obolibrary.org/obo/CHEBI_33560) [label](http://www.w3.org/2000/01/rdf-schema#label) "p-block element atom" + +- [p-block element atom](http://purl.obolibrary.org/obo/CHEBI_33560) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [p-block element atom](http://purl.obolibrary.org/obo/CHEBI_33560) + +- [p-block element atom](http://purl.obolibrary.org/obo/CHEBI_33560) SubClassOf [main group element atom](http://purl.obolibrary.org/obo/CHEBI_33318) + + + +### p-block molecular entity `http://purl.obolibrary.org/obo/CHEBI_33675` +#### Removed +- [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "p-block compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A main group molecular entity that contains one or more atoms of a p-block element." + +- [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "p-block molecular entitiy" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "p-block molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "p-block molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33675" + +- [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "p-block compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) [label](http://www.w3.org/2000/01/rdf-schema#label) "p-block molecular entity" + +- [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A p-block molecular entity is a molecular entity containing one or more atoms of a p-block element." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "p-block molecular entitiy" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- Class: [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) + +- [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) SubClassOf [main group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33579) + +- [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [p-block element atom](http://purl.obolibrary.org/obo/CHEBI_33560) + + + +### pancreatic A cell `http://purl.obolibrary.org/obo/CL_0000171` +#### Removed +- [pancreatic A cell](http://purl.obolibrary.org/obo/CL_0000171) SubClassOf [epithelial cell of pancreas](http://purl.obolibrary.org/obo/CL_0000083) + + + +### pancreatic D cell `http://purl.obolibrary.org/obo/CL_0000173` +#### Removed +- [pancreatic D cell](http://purl.obolibrary.org/obo/CL_0000173) SubClassOf [epithelial cell of pancreas](http://purl.obolibrary.org/obo/CL_0000083) + + + +### pancreatic E cell development `http://purl.obolibrary.org/obo/GO_0090105` +#### Removed +- [pancreatic E cell development](http://purl.obolibrary.org/obo/GO_0090105) SubClassOf [cell development](http://purl.obolibrary.org/obo/GO_0048468) + +#### Added +- [pancreatic E cell development](http://purl.obolibrary.org/obo/GO_0090105) SubClassOf [glandular epithelial cell development](http://purl.obolibrary.org/obo/GO_0002068) + + +### pancreatic PP cell `http://purl.obolibrary.org/obo/CL_0002275` +#### Removed +- [pancreatic PP cell](http://purl.obolibrary.org/obo/CL_0002275) SubClassOf [epithelial cell of pancreas](http://purl.obolibrary.org/obo/CL_0000083) + + + +### pancreatic centro-acinar cell `http://purl.obolibrary.org/obo/CL_0002080` +#### Removed +- [pancreatic centro-acinar cell](http://purl.obolibrary.org/obo/CL_0002080) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### pancreatic ductal cell `http://purl.obolibrary.org/obo/CL_0002079` +#### Removed +- [pancreatic ductal cell](http://purl.obolibrary.org/obo/CL_0002079) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### pancreatic endocrine cell `http://purl.obolibrary.org/obo/CL_0008024` +#### Removed +- [pancreatic endocrine cell](http://purl.obolibrary.org/obo/CL_0008024) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [pancreas](http://purl.obolibrary.org/obo/UBERON_0001264) + +- [pancreatic endocrine cell](http://purl.obolibrary.org/obo/CL_0008024) SubClassOf [endocrine cell](http://purl.obolibrary.org/obo/CL_0000163) + +#### Added +- [pancreatic endocrine cell](http://purl.obolibrary.org/obo/CL_0008024) SubClassOf [epithelial cell of pancreas](http://purl.obolibrary.org/obo/CL_0000083) + +- [pancreatic endocrine cell](http://purl.obolibrary.org/obo/CL_0008024) SubClassOf [enteroendocrine cell](http://purl.obolibrary.org/obo/CL_0000164) + + +### pancreatic epsilon cell differentiation `http://purl.obolibrary.org/obo/GO_0090104` +#### Removed +- [pancreatic epsilon cell differentiation](http://purl.obolibrary.org/obo/GO_0090104) SubClassOf [cell differentiation](http://purl.obolibrary.org/obo/GO_0030154) + +#### Added +- [pancreatic epsilon cell differentiation](http://purl.obolibrary.org/obo/GO_0090104) SubClassOf [enteroendocrine cell differentiation](http://purl.obolibrary.org/obo/GO_0035883) + + +### paneth cell `http://purl.obolibrary.org/obo/CL_0000510` +#### Removed +- [paneth cell](http://purl.obolibrary.org/obo/CL_0000510) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An epithelial cell found in the basal part of the intestinal glands (crypts of Lieberkuhn) including the appendix. Paneth cells synthesize and secrete lysozyme and cryptdins. Numerous in the deeper parts of the intestinal crypts, particularly in the duodenum, rich in zinc, contain large acidophilic granules, with irregular apical microvilli and prominent membrane-bound vacuoles containing matrix." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D019879" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tfm" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0517223651" + +#### Added +- [paneth cell](http://purl.obolibrary.org/obo/CL_0000510) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An epithelial cell found in the basal part of the intestinal glands (crypts of Lieberkuhn) including the appendix. Paneth cells synthesize and secrete lysozyme and cryptdins. Numerous in the deeper parts of the intestinal crypts, particularly in the duodenum, rich in zinc, contain large acidophilic granules, with irregular apical microvilli and prominent membrane-bound vacuoles containing matrix." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D019879" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tfm" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:29184701" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0517223651" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32308658" + +- [paneth cell](http://purl.obolibrary.org/obo/CL_0000510) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [crypt of Lieberkuhn](http://purl.obolibrary.org/obo/UBERON_0001983) + + +### paneth cell of epithelium of crypt of Lieberkuhn of small intestine `http://purl.obolibrary.org/obo/CL_1000345` +#### Removed +- [paneth cell of epithelium of crypt of Lieberkuhn of small intestine](http://purl.obolibrary.org/obo/CL_1000345) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [crypt of Lieberkuhn](http://purl.obolibrary.org/obo/UBERON_0001983) + + + +### parasol ganglion cell of retina `http://purl.obolibrary.org/obo/CL_4023189` +#### Removed +- [parasol ganglion cell of retina](http://purl.obolibrary.org/obo/CL_4023189) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A retinal ganglion cell ocated in the ganglion cell layer of the retina and projects to magnocellular cells in the lateral geniculate nucleus (LGN) as part of the magnocellular pathway in the visual system. They have large cell bodies as well as extensive branching dendrite networks and as such have large receptive fields." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32533915" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WikipediaVersioned:Parasol_cell&oldid=1032171532" + +#### Added +- [parasol ganglion cell of retina](http://purl.obolibrary.org/obo/CL_4023189) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A retinal ganglion cell located in the ganglion cell layer of the retina. This cell projects to magnocellular cells in the lateral geniculate nucleus (LGN). They have large cell bodies and extensive, branching dendritic networks that contribute to their large receptive fields." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32533915" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WikipediaVersioned:Parasol_cell&oldid=1032171532" + + +### parietal epithelial cell `http://purl.obolibrary.org/obo/CL_1000452` +#### Removed +- [parietal epithelial cell](http://purl.obolibrary.org/obo/CL_1000452) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000897" + + + +### part of developmental precursor of `http://purl.obolibrary.org/obo/RO_0002287` +#### Removed +- [part of developmental precursor of](http://purl.obolibrary.org/obo/RO_0002287) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [part of developmental precursor of](http://purl.obolibrary.org/obo/RO_0002287) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### part of structure that is capable of `http://purl.obolibrary.org/obo/RO_0002329` +#### Removed +- [part of structure that is capable of](http://purl.obolibrary.org/obo/RO_0002329) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [part of structure that is capable of](http://purl.obolibrary.org/obo/RO_0002329) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### peptide `http://purl.obolibrary.org/obo/CHEBI_16670` +#### Removed +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." + +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14753" + +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:7990" + +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00012" + +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) [label](http://www.w3.org/2000/01/rdf-schema#label) "peptide" + +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "peptidos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) [formula](http://purl.obolibrary.org/obo/chebi/formula) "(C2H2NOR)nC2H3NOR" + +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:25906" + +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Peptide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "peptido" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "peptides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Peptid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) SubClassOf [is_tautomer_of](http://purl.obolibrary.org/obo/chebi#is_tautomer_of) some [peptide zwitterion](http://purl.obolibrary.org/obo/CHEBI_60466) + +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) SubClassOf [carboxamide](http://purl.obolibrary.org/obo/CHEBI_37622) + +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) SubClassOf [organic amino compound](http://purl.obolibrary.org/obo/CHEBI_50047) + +- [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33708) + + + +### peptide binding `http://purl.obolibrary.org/obo/GO_0042277` +#### Removed +- [peptide binding](http://purl.obolibrary.org/obo/GO_0042277) SubClassOf [amide binding](http://purl.obolibrary.org/obo/GO_0033218) + +#### Added +- [peptide binding](http://purl.obolibrary.org/obo/GO_0042277) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### peptide biosynthetic process `http://purl.obolibrary.org/obo/GO_0043043` +#### Removed +- [peptide biosynthetic process](http://purl.obolibrary.org/obo/GO_0043043) SubClassOf [organonitrogen compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901566) + +- [peptide biosynthetic process](http://purl.obolibrary.org/obo/GO_0043043) SubClassOf [amide biosynthetic process](http://purl.obolibrary.org/obo/GO_0043604) + +#### Added +- [peptide biosynthetic process](http://purl.obolibrary.org/obo/GO_0043043) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### peptide catabolic process `http://purl.obolibrary.org/obo/GO_0043171` +#### Removed +- [peptide catabolic process](http://purl.obolibrary.org/obo/GO_0043171) SubClassOf [organonitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_1901565) + + + +### peptide hormone `http://purl.obolibrary.org/obo/CHEBI_25905` +#### Removed +- [peptide hormone](http://purl.obolibrary.org/obo/CHEBI_25905) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "peptide hormones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [peptide hormone](http://purl.obolibrary.org/obo/CHEBI_25905) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine." + +- [peptide hormone](http://purl.obolibrary.org/obo/CHEBI_25905) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [peptide hormone](http://purl.obolibrary.org/obo/CHEBI_25905) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polypeptide hormone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [peptide hormone](http://purl.obolibrary.org/obo/CHEBI_25905) [label](http://www.w3.org/2000/01/rdf-schema#label) "peptide hormone" + +- [peptide hormone](http://purl.obolibrary.org/obo/CHEBI_25905) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [peptide hormone](http://purl.obolibrary.org/obo/CHEBI_25905) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25905" + +- [peptide hormone](http://purl.obolibrary.org/obo/CHEBI_25905) SubClassOf [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) + +- [peptide hormone](http://purl.obolibrary.org/obo/CHEBI_25905) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [hormone](http://purl.obolibrary.org/obo/CHEBI_24621) + + + +### peptide hormone binding `http://purl.obolibrary.org/obo/GO_0017046` +#### Removed +- [peptide hormone binding](http://purl.obolibrary.org/obo/GO_0017046) SubClassOf [peptide binding](http://purl.obolibrary.org/obo/GO_0042277) + + + +### peptide hormone processing `http://purl.obolibrary.org/obo/GO_0016486` +#### Removed +- [peptide hormone processing](http://purl.obolibrary.org/obo/GO_0016486) SubClassOf [peptide metabolic process](http://purl.obolibrary.org/obo/GO_0006518) + + + +### peptide metabolic process `http://purl.obolibrary.org/obo/GO_0006518` +#### Removed +- [peptide metabolic process](http://purl.obolibrary.org/obo/GO_0006518) SubClassOf [organonitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_1901564) + +- [peptide metabolic process](http://purl.obolibrary.org/obo/GO_0006518) SubClassOf [amide metabolic process](http://purl.obolibrary.org/obo/GO_0043603) + +#### Added +- [peptide metabolic process](http://purl.obolibrary.org/obo/GO_0006518) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### peptide transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_1904680` +#### Removed +- [peptide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1904680) SubClassOf [amide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0042887) + +#### Added +- [peptide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1904680) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + +### peptide zwitterion `http://purl.obolibrary.org/obo/CHEBI_60466` +#### Removed +- [peptide zwitterion](http://purl.obolibrary.org/obo/CHEBI_60466) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "peptide zwitterions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [peptide zwitterion](http://purl.obolibrary.org/obo/CHEBI_60466) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged." + +- [peptide zwitterion](http://purl.obolibrary.org/obo/CHEBI_60466) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a peptide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [peptide zwitterion](http://purl.obolibrary.org/obo/CHEBI_60466) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2H4NO2R(C2H2NOR)n" + +- [peptide zwitterion](http://purl.obolibrary.org/obo/CHEBI_60466) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [peptide zwitterion](http://purl.obolibrary.org/obo/CHEBI_60466) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [peptide zwitterion](http://purl.obolibrary.org/obo/CHEBI_60466) [label](http://www.w3.org/2000/01/rdf-schema#label) "peptide zwitterion" + +- [peptide zwitterion](http://purl.obolibrary.org/obo/CHEBI_60466) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:60466" + +- [peptide zwitterion](http://purl.obolibrary.org/obo/CHEBI_60466) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [peptide zwitterion](http://purl.obolibrary.org/obo/CHEBI_60466) + +- [peptide zwitterion](http://purl.obolibrary.org/obo/CHEBI_60466) SubClassOf [zwitterion](http://purl.obolibrary.org/obo/CHEBI_27369) + +- [peptide zwitterion](http://purl.obolibrary.org/obo/CHEBI_60466) SubClassOf [is_tautomer_of](http://purl.obolibrary.org/obo/chebi#is_tautomer_of) some [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) + + + +### perichondrial fibroblast `http://purl.obolibrary.org/obo/CL_4033025` + +#### Added +- [perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033025) [date](http://purl.org/dc/terms/date) "2023-03-16T16:12:50Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033025) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- [perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033025) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-9185-3994](https://orcid.org/0000-0002-9185-3994) + +- [perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033025) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A fibroblast that is part of the fibrous layer of the perichondrium. This cell is responsible for collagen fiber production." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "wikipedia:Perichondrium" + +- [perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033025) [label](http://www.w3.org/2000/01/rdf-schema#label) "perichondrial fibroblast" + +- Class: [perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033025) + +- [perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033025) EquivalentTo [fibroblast](http://purl.obolibrary.org/obo/CL_0000057) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [outer fibrous layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008305)) + +- [perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033025) SubClassOf [fibroblast](http://purl.obolibrary.org/obo/CL_0000057) + +- [perichondrial fibroblast](http://purl.obolibrary.org/obo/CL_4033025) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [outer fibrous layer of perichondrium](http://purl.obolibrary.org/obo/UBERON_0008305) + + +### perichondrium `http://purl.obolibrary.org/obo/UBERON_0002222` + +#### Added +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "AAO:0010445" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0002222" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "SCTID:11881003" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [pheno_slim](http://purl.obolibrary.org/obo/uberon/core#pheno_slim) + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0005089" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "perichondral region of cartilage" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [UBPROP_0000001](http://purl.obolibrary.org/obo/UBPROP_0000001) "Portion of connective tissue which surrounds cartilage.[TAO]" + - [ontology](http://www.geneontology.org/formats/oboInOwl#ontology) "TAO" + + - [date_retrieved](http://www.geneontology.org/formats/oboInOwl#date_retrieved) "2012-08-14" + + - [source](http://www.geneontology.org/formats/oboInOwl#source) "TAO:wd" + + - [external_class](http://www.geneontology.org/formats/oboInOwl#external_class) "TAO:0001643" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "perichondral region of cartilage element" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EMAPA:35676" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MA:0003008" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Perichondrium" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ZFA:0001634" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [vertebrate_core](http://purl.obolibrary.org/obo/uberon/core#vertebrate_core) + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [label](http://www.w3.org/2000/01/rdf-schema#label) "perichondrium" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Fibrous connective tissue that surrounds cartilage." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "VSAO:0000036" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000034" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://dx.plos.org/10.1371/journal.pone.0051070" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PSPUB:0000170" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://github.com/obophenotype/uberon/issues/26" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "TAO:0001643" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [uberon_slim](http://purl.obolibrary.org/obo/uberon/core#uberon_slim) + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "VSAO:0000036" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cartilage connective tissue" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "XAO:0004049" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75446" + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- Class: [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) SubClassOf [bounding layer of](http://purl.obolibrary.org/obo/RO_0002007) some [cartilage element](http://purl.obolibrary.org/obo/UBERON_0007844) + +- [perichondrium](http://purl.obolibrary.org/obo/UBERON_0002222) SubClassOf [connective tissue](http://purl.obolibrary.org/obo/UBERON_0002384) + - [source](http://www.geneontology.org/formats/oboInOwl#source) "VSAO" + + +### pericyte `http://purl.obolibrary.org/obo/CL_0000669` +#### Removed +- [pericyte](http://purl.obolibrary.org/obo/CL_0000669) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000184" + + + +### peripheral nervous system neuron `http://purl.obolibrary.org/obo/CL_2000032` +#### Removed +- [peripheral nervous system neuron](http://purl.obolibrary.org/obo/CL_2000032) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000111" + + + +### peritoneal macrophage `http://purl.obolibrary.org/obo/CL_0000581` +#### Removed +- [peritoneal macrophage](http://purl.obolibrary.org/obo/CL_0000581) EquivalentTo [tissue-resident macrophage](http://purl.obolibrary.org/obo/CL_0000864) and ([located in](http://purl.obolibrary.org/obo/RO_0001025) some [peritoneal cavity](http://purl.obolibrary.org/obo/UBERON_0001179)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-type lectin domain family 7 member A](http://purl.obolibrary.org/obo/PR_000001807)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrosialin](http://purl.obolibrary.org/obo/PR_000002064)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD209 molecule-like protein B](http://purl.obolibrary.org/obo/PR_000006172)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [defense response to bacterium](http://purl.obolibrary.org/obo/GO_0042742)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [macrophage colony-stimulating factor 1 receptor](http://purl.obolibrary.org/obo/PR_000002062)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) + +- [peritoneal macrophage](http://purl.obolibrary.org/obo/CL_0000581) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613) + +#### Added +- [peritoneal macrophage](http://purl.obolibrary.org/obo/CL_0000581) EquivalentTo [tissue-resident macrophage](http://purl.obolibrary.org/obo/CL_0000864) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([located in](http://purl.obolibrary.org/obo/RO_0001025) some [peritoneal cavity](http://purl.obolibrary.org/obo/UBERON_0001179)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-type lectin domain family 7 member A](http://purl.obolibrary.org/obo/PR_000001807)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrosialin](http://purl.obolibrary.org/obo/PR_000002064)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD209 molecule-like protein B](http://purl.obolibrary.org/obo/PR_000006172)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [defense response to bacterium](http://purl.obolibrary.org/obo/GO_0042742)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [macrophage colony-stimulating factor 1 receptor](http://purl.obolibrary.org/obo/PR_000002062)) + +- [peritoneal macrophage](http://purl.obolibrary.org/obo/CL_0000581) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613) + + +### phagocytosis `http://purl.obolibrary.org/obo/GO_0006909` +#### Removed +- [phagocytosis](http://purl.obolibrary.org/obo/GO_0006909) SubClassOf [vesicle-mediated transport](http://purl.obolibrary.org/obo/GO_0016192) + +#### Added +- [phagocytosis](http://purl.obolibrary.org/obo/GO_0006909) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24907"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [phagocytosis](http://purl.obolibrary.org/obo/GO_0006909) SubClassOf [endocytosis](http://purl.obolibrary.org/obo/GO_0006897) + + +### pharmaceutical `http://purl.obolibrary.org/obo/CHEBI_52217` +#### Removed +- [pharmaceutical](http://purl.obolibrary.org/obo/CHEBI_52217) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "medicament" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [pharmaceutical](http://purl.obolibrary.org/obo/CHEBI_52217) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [pharmaceutical](http://purl.obolibrary.org/obo/CHEBI_52217) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "farmaco" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [pharmaceutical](http://purl.obolibrary.org/obo/CHEBI_52217) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [pharmaceutical](http://purl.obolibrary.org/obo/CHEBI_52217) [label](http://www.w3.org/2000/01/rdf-schema#label) "pharmaceutical" + +- [pharmaceutical](http://purl.obolibrary.org/obo/CHEBI_52217) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any substance introduced into a living organism with therapeutic or diagnostic purpose." + +- [pharmaceutical](http://purl.obolibrary.org/obo/CHEBI_52217) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:52217" + +- [pharmaceutical](http://purl.obolibrary.org/obo/CHEBI_52217) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:33293" + +- [pharmaceutical](http://purl.obolibrary.org/obo/CHEBI_52217) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:33294" + +- [pharmaceutical](http://purl.obolibrary.org/obo/CHEBI_52217) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pharmaceuticals" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [pharmaceutical](http://purl.obolibrary.org/obo/CHEBI_52217) + +- [pharmaceutical](http://purl.obolibrary.org/obo/CHEBI_52217) SubClassOf [application](http://purl.obolibrary.org/obo/CHEBI_33232) + + + +### pharmacological role `http://purl.obolibrary.org/obo/CHEBI_52210` +#### Removed +- [pharmacological role](http://purl.obolibrary.org/obo/CHEBI_52210) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties." + +- [pharmacological role](http://purl.obolibrary.org/obo/CHEBI_52210) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:52210" + +- [pharmacological role](http://purl.obolibrary.org/obo/CHEBI_52210) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [pharmacological role](http://purl.obolibrary.org/obo/CHEBI_52210) [label](http://www.w3.org/2000/01/rdf-schema#label) "pharmacological role" + +- [pharmacological role](http://purl.obolibrary.org/obo/CHEBI_52210) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [pharmacological role](http://purl.obolibrary.org/obo/CHEBI_52210) + +- [pharmacological role](http://purl.obolibrary.org/obo/CHEBI_52210) SubClassOf [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) + + + +### phenol-containing compound biosynthetic process `http://purl.obolibrary.org/obo/GO_0046189` +#### Removed +- [phenol-containing compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0046189) SubClassOf [aromatic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0019438) + +- [phenol-containing compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0046189) SubClassOf [organic cyclic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901362) + +- [phenol-containing compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0046189) SubClassOf [organic hydroxy compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901617) + +#### Added +- [phenol-containing compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0046189) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### phenol-containing compound catabolic process `http://purl.obolibrary.org/obo/GO_0019336` +#### Removed +- [phenol-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0019336) SubClassOf [organic cyclic compound catabolic process](http://purl.obolibrary.org/obo/GO_1901361) + +- [phenol-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0019336) SubClassOf [aromatic compound catabolic process](http://purl.obolibrary.org/obo/GO_0019439) + +- [phenol-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0019336) SubClassOf [organic hydroxy compound catabolic process](http://purl.obolibrary.org/obo/GO_1901616) + +#### Added +- [phenol-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0019336) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### phenolic steroid `http://purl.obolibrary.org/obo/CHEBI_177917` +#### Removed +- [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "HJKVPZJVBHWFCQ-UHFFFAOYSA-N" + +- [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C1=C2C(CCC3C4CCCC4(CCC32)C)=CC(=C1)O" + +- [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C18H24O" + +- [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:PHENOLIC-STEROID" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "SUBMITTER" + +- [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) [mass](http://purl.obolibrary.org/obo/chebi/mass) "256.389" + +- [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "256.18272" + +- [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C18H24O/c1-18-9-2-3-17(18)16-6-4-12-11-13(19)5-7-14(12)15(16)8-10-18/h5,7,11,15-17,19H,2-4,6,8-10H2,1H3" + +- [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C02453" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "SUBMITTER" + +- [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) [label](http://www.w3.org/2000/01/rdf-schema#label) "phenolic steroid" + +- [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#2_STAR) + +- [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a phenolic steroid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:177917" + +- [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) + +- [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) SubClassOf [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) + +- [phenolic steroid](http://purl.obolibrary.org/obo/CHEBI_177917) SubClassOf [3-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_36834) + + + +### phenols `http://purl.obolibrary.org/obo/CHEBI_33853` +#### Removed +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Phenols" + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:25969" + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [label](http://www.w3.org/2000/01/rdf-schema#label) "phenols" + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [mass](http://purl.obolibrary.org/obo/chebi/mass) "89.072" + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "89.00274" + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:Phenols" + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arenols" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C1(=C(C(=C(C(=C1*)*)*)*)*)O" + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Aryl alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C15584" + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a phenol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13664" + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13825" + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:2857" + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C6HOR5" + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phenols" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring." + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) SubClassOf [organic aromatic compound](http://purl.obolibrary.org/obo/CHEBI_33659) + +- [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) SubClassOf [organic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_33822) + + + +### phosphate `http://purl.obolibrary.org/obo/CHEBI_26020` +#### Removed +- [phosphate](http://purl.obolibrary.org/obo/CHEBI_26020) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphate" + +- [phosphate](http://purl.obolibrary.org/obo/CHEBI_26020) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "phosphates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphate](http://purl.obolibrary.org/obo/CHEBI_26020) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phosphates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [phosphate](http://purl.obolibrary.org/obo/CHEBI_26020) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26020" + +- [phosphate](http://purl.obolibrary.org/obo/CHEBI_26020) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [phosphate](http://purl.obolibrary.org/obo/CHEBI_26020) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [phosphate](http://purl.obolibrary.org/obo/CHEBI_26020) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom." + +- [phosphate](http://purl.obolibrary.org/obo/CHEBI_26020) SubClassOf [phosphoric acid derivative](http://purl.obolibrary.org/obo/CHEBI_26079) + + + +### phosphate ion `http://purl.obolibrary.org/obo/CHEBI_35780` +#### Removed +- [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "phosphate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Pi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphate ion" + +- [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35780" + +- [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A phosphorus oxoanion that is the conjugate base of phosphoric acid." + +- [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "phosphate ions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) + +- [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) SubClassOf [phosphorus oxoanion](http://purl.obolibrary.org/obo/CHEBI_33461) + +- [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) + + + +### phosphate ion binding `http://purl.obolibrary.org/obo/GO_0042301` +#### Removed +- [phosphate ion binding](http://purl.obolibrary.org/obo/GO_0042301) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to a phosphate ion." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [phosphate ion binding](http://purl.obolibrary.org/obo/GO_0042301) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphate ion binding" + +- [phosphate ion binding](http://purl.obolibrary.org/obo/GO_0042301) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0042301" + +- [phosphate ion binding](http://purl.obolibrary.org/obo/GO_0042301) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- Class: [phosphate ion binding](http://purl.obolibrary.org/obo/GO_0042301) + +- [phosphate ion binding](http://purl.obolibrary.org/obo/GO_0042301) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780)) + +- [phosphate ion binding](http://purl.obolibrary.org/obo/GO_0042301) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) + +- [phosphate ion binding](http://purl.obolibrary.org/obo/GO_0042301) SubClassOf [anion binding](http://purl.obolibrary.org/obo/GO_0043168) + + + +### phosphate ion homeostasis `http://purl.obolibrary.org/obo/GO_0055062` +#### Removed +- [phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055062) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055062) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jid" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055062) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0055062" + +- [phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055062) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphate ion homeostasis" + +- Class: [phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055062) + +- [phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055062) EquivalentTo [chemical homeostasis](http://purl.obolibrary.org/obo/GO_0048878) and ([regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780)) + +- [phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055062) SubClassOf [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) + +- [phosphate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055062) SubClassOf [inorganic ion homeostasis](http://purl.obolibrary.org/obo/GO_0098771) + + + +### phosphate ion transmembrane transport `http://purl.obolibrary.org/obo/GO_0035435` +#### Removed +- [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-04-08T11:24:06Z" + +- [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The process in which a phosphate is transported across a membrane." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:vw" + +- [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phosphate ion membrane transport" + +- [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphate ion transmembrane transport" + +- [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0035435" + +- [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "bf" + +- [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Note that this term is not intended for use in annotating lateral movement within membranes." + +- Class: [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435) + +- [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([results in transport across](http://purl.obolibrary.org/obo/RO_0002342) some [membrane](http://purl.obolibrary.org/obo/GO_0016020)) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780)) + +- [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435) SubClassOf [phosphate ion transport](http://purl.obolibrary.org/obo/GO_0006817) + +- [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435) SubClassOf [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661) + + + +### phosphate ion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015114` +#### Removed +- [phosphate ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015114) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "RHEA:32823" + +- [phosphate ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015114) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphate ion transmembrane transporter activity" + +- [phosphate ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015114) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "pr" + +- [phosphate ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015114) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [phosphate ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015114) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015114" + +- [phosphate ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015114) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-11-22T15:43:10Z" + +- [phosphate ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015114) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:1901677" + +- [phosphate ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015114) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "phosphate transmembrane transporter activity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:vw" + +- [phosphate ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015114) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- Class: [phosphate ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015114) + +- [phosphate ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015114) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780)) + +- [phosphate ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015114) SubClassOf [inorganic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015103) + +- [phosphate ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015114) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435) + - [source](http://www.geneontology.org/formats/oboInOwl#http://purl.org/dc/terms/source) "GO_REF:0000090" + +- [phosphate ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015114) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) + + + +### phosphate ion transport `http://purl.obolibrary.org/obo/GO_0006817` +#### Removed +- [phosphate ion transport](http://purl.obolibrary.org/obo/GO_0006817) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [phosphate ion transport](http://purl.obolibrary.org/obo/GO_0006817) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphate ion transport" + +- [phosphate ion transport](http://purl.obolibrary.org/obo/GO_0006817) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [phosphate ion transport](http://purl.obolibrary.org/obo/GO_0006817) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006817" + +- [phosphate ion transport](http://purl.obolibrary.org/obo/GO_0006817) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "phosphate transport" + +- Class: [phosphate ion transport](http://purl.obolibrary.org/obo/GO_0006817) + +- [phosphate ion transport](http://purl.obolibrary.org/obo/GO_0006817) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780)) + +- [phosphate ion transport](http://purl.obolibrary.org/obo/GO_0006817) SubClassOf [inorganic anion transport](http://purl.obolibrary.org/obo/GO_0015698) + +- [phosphate ion transport](http://purl.obolibrary.org/obo/GO_0006817) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) + + + +### phosphate mineral `http://purl.obolibrary.org/obo/CHEBI_46723` +#### Removed +- [phosphate mineral](http://purl.obolibrary.org/obo/CHEBI_46723) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [phosphate mineral](http://purl.obolibrary.org/obo/CHEBI_46723) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphate mineral" + +- [phosphate mineral](http://purl.obolibrary.org/obo/CHEBI_46723) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [phosphate mineral](http://purl.obolibrary.org/obo/CHEBI_46723) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "phosphate minerals" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphate mineral](http://purl.obolibrary.org/obo/CHEBI_46723) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:46723" + +- Class: [phosphate mineral](http://purl.obolibrary.org/obo/CHEBI_46723) + +- [phosphate mineral](http://purl.obolibrary.org/obo/CHEBI_46723) SubClassOf [mineral](http://purl.obolibrary.org/obo/CHEBI_46662) + + + +### phosphate(3-) `http://purl.obolibrary.org/obo/CHEBI_18367` +#### Removed +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "94.95507" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:45024" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [mass](http://purl.obolibrary.org/obo/chebi/mass) "94.97136" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Phosphate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14791" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphate(3-)" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:PO4" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChEBI" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetraoxophosphate(3-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Orthophosphate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetraoxophosphate(V)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-3" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "PO4(3-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:14265-44-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[O-]P([O-])([O-])=O" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[PO4](3-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetraoxidophosphate(3-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:14265-44-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "NBIIXXVUZAFLBC-UHFFFAOYSA-K" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "PHOSPHATE ION" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:1997" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [formula](http://purl.obolibrary.org/obo/chebi/formula) "O4P" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:3903772" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00009" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:3903772" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:7793" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phosphate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:18367" + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A phosphate ion that is the conjugate base of hydrogenphosphate." + +- Class: [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [hydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_43474) + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) SubClassOf [phosphate ion](http://purl.obolibrary.org/obo/CHEBI_35780) + +- [phosphate(3-)](http://purl.obolibrary.org/obo/CHEBI_18367) SubClassOf [trivalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79387) + + + +### phosphate-containing compound metabolic process `http://purl.obolibrary.org/obo/GO_0006796` +#### Removed +- [phosphate-containing compound metabolic process](http://purl.obolibrary.org/obo/GO_0006796) SubClassOf [phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0006793) + +#### Added +- [phosphate-containing compound metabolic process](http://purl.obolibrary.org/obo/GO_0006796) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### phosphoric acid `http://purl.obolibrary.org/obo/CHEBI_26078` +#### Removed +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22381614" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "H3PO4" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acide phosphorique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7664-38-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Phosphorsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Phosphoric_Acid" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:2000" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Phosphoric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11455380" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acidum phosphoricum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "orthophosphoric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22401268" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:4478" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [formula](http://purl.obolibrary.org/obo/chebi/formula) "H3O4P" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "trihydroxidooxidophosphorus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:1921286" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetraoxophosphoric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22282755" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7664-38-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Orthophosphoric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "NBIIXXVUZAFLBC-UHFFFAOYSA-N" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "trihydrogen tetraoxophosphate(3-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D05467" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00009" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00007408" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7664-38-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphoric acid" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phosphoric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom." + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [mass](http://purl.obolibrary.org/obo/chebi/mass) "97.99520" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Phosphorsaeureloesungen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Phosphate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "97.97690" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15630224" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H]OP(=O)(O[H])O[H]" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[PO(OH)3]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0002142" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17439666" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22333268" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26078" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17518491" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:1921286" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- Class: [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) SubClassOf [phosphoric acids](http://purl.obolibrary.org/obo/CHEBI_59698) + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [solvent](http://purl.obolibrary.org/obo/CHEBI_46787) + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [dihydrogenphosphate](http://purl.obolibrary.org/obo/CHEBI_39745) + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [algal metabolite](http://purl.obolibrary.org/obo/CHEBI_84735) + +- [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [fertilizer](http://purl.obolibrary.org/obo/CHEBI_33287) + + + +### phosphoric acid derivative `http://purl.obolibrary.org/obo/CHEBI_26079` +#### Removed +- [phosphoric acid derivative](http://purl.obolibrary.org/obo/CHEBI_26079) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26079" + +- [phosphoric acid derivative](http://purl.obolibrary.org/obo/CHEBI_26079) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#1_STAR) + +- [phosphoric acid derivative](http://purl.obolibrary.org/obo/CHEBI_26079) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphoric acid derivative" + +- [phosphoric acid derivative](http://purl.obolibrary.org/obo/CHEBI_26079) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [phosphoric acid derivative](http://purl.obolibrary.org/obo/CHEBI_26079) + +- [phosphoric acid derivative](http://purl.obolibrary.org/obo/CHEBI_26079) SubClassOf [phosphorus oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_36359) + +- [phosphoric acid derivative](http://purl.obolibrary.org/obo/CHEBI_26079) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [phosphoric acid](http://purl.obolibrary.org/obo/CHEBI_26078) + + + +### phosphoric acids `http://purl.obolibrary.org/obo/CHEBI_59698` +#### Removed +- [phosphoric acids](http://purl.obolibrary.org/obo/CHEBI_59698) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphoric acids" + +- [phosphoric acids](http://purl.obolibrary.org/obo/CHEBI_59698) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Compounds containing one or more phosphoric acid units." + +- [phosphoric acids](http://purl.obolibrary.org/obo/CHEBI_59698) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:59698" + +- [phosphoric acids](http://purl.obolibrary.org/obo/CHEBI_59698) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [phosphoric acids](http://purl.obolibrary.org/obo/CHEBI_59698) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [phosphoric acids](http://purl.obolibrary.org/obo/CHEBI_59698) + +- [phosphoric acids](http://purl.obolibrary.org/obo/CHEBI_59698) SubClassOf [phosphorus oxoacid](http://purl.obolibrary.org/obo/CHEBI_33457) + + + +### phosphorus atom `http://purl.obolibrary.org/obo/CHEBI_28659` +#### Removed +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Phosphorus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "30.97376" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "OAICVXFJPJFONN-UHFFFAOYSA-N" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [formula](http://purl.obolibrary.org/obo/chebi/formula) "P" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fosforo" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphorus atom" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:16235" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/P" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Phosphor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C06262" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:28659" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7723-14-0" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[P]" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "P" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [mass](http://purl.obolibrary.org/obo/chebi/mass) "30.97376" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "phosphorus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:26080" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phosphorus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:8168" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "P" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WebElements:P" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7723-14-0" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "15P" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "phosphore" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [macronutrient](http://purl.obolibrary.org/obo/CHEBI_33937) + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) SubClassOf [pnictogen](http://purl.obolibrary.org/obo/CHEBI_33300) + +- [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) SubClassOf [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) + + + +### phosphorus metabolic process `http://purl.obolibrary.org/obo/GO_0006793` +#### Removed +- [phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0006793) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_pir](http://purl.obolibrary.org/obo/go#goslim_pir) + +- [phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0006793) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0006793) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006793" + +- [phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0006793) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphorus metabolic process" + +- [phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0006793) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0006793) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phosphorus metabolism" + +- Class: [phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0006793) + +- [phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0006793) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [phosphorus molecular entity](http://purl.obolibrary.org/obo/CHEBI_26082)) + +- [phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0006793) SubClassOf [cellular metabolic process](http://purl.obolibrary.org/obo/GO_0044237) + +- [phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0006793) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [phosphorus molecular entity](http://purl.obolibrary.org/obo/CHEBI_26082) + + + +### phosphorus molecular entity `http://purl.obolibrary.org/obo/CHEBI_26082` +#### Removed +- [phosphorus molecular entity](http://purl.obolibrary.org/obo/CHEBI_26082) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [phosphorus molecular entity](http://purl.obolibrary.org/obo/CHEBI_26082) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26082" + +- [phosphorus molecular entity](http://purl.obolibrary.org/obo/CHEBI_26082) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "phosphorus molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphorus molecular entity](http://purl.obolibrary.org/obo/CHEBI_26082) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [phosphorus molecular entity](http://purl.obolibrary.org/obo/CHEBI_26082) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphorus molecular entity" + +- Class: [phosphorus molecular entity](http://purl.obolibrary.org/obo/CHEBI_26082) + +- [phosphorus molecular entity](http://purl.obolibrary.org/obo/CHEBI_26082) SubClassOf [pnictogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33302) + +- [phosphorus molecular entity](http://purl.obolibrary.org/obo/CHEBI_26082) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [phosphorus atom](http://purl.obolibrary.org/obo/CHEBI_28659) + + + +### phosphorus oxoacid `http://purl.obolibrary.org/obo/CHEBI_33457` +#### Removed +- [phosphorus oxoacid](http://purl.obolibrary.org/obo/CHEBI_33457) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons." + +- [phosphorus oxoacid](http://purl.obolibrary.org/obo/CHEBI_33457) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33457" + +- [phosphorus oxoacid](http://purl.obolibrary.org/obo/CHEBI_33457) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [phosphorus oxoacid](http://purl.obolibrary.org/obo/CHEBI_33457) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phosphorus oxoacid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphorus oxoacid](http://purl.obolibrary.org/obo/CHEBI_33457) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxoacids of phosphorus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphorus oxoacid](http://purl.obolibrary.org/obo/CHEBI_33457) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Oxosaeure des Phosphors" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphorus oxoacid](http://purl.obolibrary.org/obo/CHEBI_33457) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "phosphorus oxoacids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphorus oxoacid](http://purl.obolibrary.org/obo/CHEBI_33457) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [phosphorus oxoacid](http://purl.obolibrary.org/obo/CHEBI_33457) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphorus oxoacid" + +- Class: [phosphorus oxoacid](http://purl.obolibrary.org/obo/CHEBI_33457) + +- [phosphorus oxoacid](http://purl.obolibrary.org/obo/CHEBI_33457) SubClassOf [phosphorus oxoacids and derivatives](http://purl.obolibrary.org/obo/CHEBI_36360) + +- [phosphorus oxoacid](http://purl.obolibrary.org/obo/CHEBI_33457) SubClassOf [pnictogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33408) + + + +### phosphorus oxoacid derivative `http://purl.obolibrary.org/obo/CHEBI_36359` +#### Removed +- [phosphorus oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_36359) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phosphorus oxoacid derivative" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphorus oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_36359) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [phosphorus oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_36359) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36359" + +- [phosphorus oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_36359) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphorus oxoacid derivative" + +- [phosphorus oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_36359) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [phosphorus oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_36359) + +- [phosphorus oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_36359) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [phosphorus oxoacid](http://purl.obolibrary.org/obo/CHEBI_33457) + +- [phosphorus oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_36359) SubClassOf [oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33241) + +- [phosphorus oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_36359) SubClassOf [phosphorus oxoacids and derivatives](http://purl.obolibrary.org/obo/CHEBI_36360) + + + +### phosphorus oxoacids and derivatives `http://purl.obolibrary.org/obo/CHEBI_36360` +#### Removed +- [phosphorus oxoacids and derivatives](http://purl.obolibrary.org/obo/CHEBI_36360) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36360" + +- [phosphorus oxoacids and derivatives](http://purl.obolibrary.org/obo/CHEBI_36360) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#1_STAR) + +- [phosphorus oxoacids and derivatives](http://purl.obolibrary.org/obo/CHEBI_36360) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphorus oxoacids and derivatives" + +- [phosphorus oxoacids and derivatives](http://purl.obolibrary.org/obo/CHEBI_36360) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [phosphorus oxoacids and derivatives](http://purl.obolibrary.org/obo/CHEBI_36360) + +- [phosphorus oxoacids and derivatives](http://purl.obolibrary.org/obo/CHEBI_36360) SubClassOf [phosphorus molecular entity](http://purl.obolibrary.org/obo/CHEBI_26082) + + + +### phosphorus oxoanion `http://purl.obolibrary.org/obo/CHEBI_33461` +#### Removed +- [phosphorus oxoanion](http://purl.obolibrary.org/obo/CHEBI_33461) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33461" + +- [phosphorus oxoanion](http://purl.obolibrary.org/obo/CHEBI_33461) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "phosphorus oxoanions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphorus oxoanion](http://purl.obolibrary.org/obo/CHEBI_33461) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxoanions of phosphorus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphorus oxoanion](http://purl.obolibrary.org/obo/CHEBI_33461) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [phosphorus oxoanion](http://purl.obolibrary.org/obo/CHEBI_33461) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phosphorus oxoanion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [phosphorus oxoanion](http://purl.obolibrary.org/obo/CHEBI_33461) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [phosphorus oxoanion](http://purl.obolibrary.org/obo/CHEBI_33461) [label](http://www.w3.org/2000/01/rdf-schema#label) "phosphorus oxoanion" + +- Class: [phosphorus oxoanion](http://purl.obolibrary.org/obo/CHEBI_33461) + +- [phosphorus oxoanion](http://purl.obolibrary.org/obo/CHEBI_33461) SubClassOf [pnictogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33459) + +- [phosphorus oxoanion](http://purl.obolibrary.org/obo/CHEBI_33461) SubClassOf [inorganic anion](http://purl.obolibrary.org/obo/CHEBI_24834) + +- [phosphorus oxoanion](http://purl.obolibrary.org/obo/CHEBI_33461) SubClassOf [phosphorus molecular entity](http://purl.obolibrary.org/obo/CHEBI_26082) + + + +### phosphorylates `http://purl.obolibrary.org/obo/RO_0002447` +#### Removed +- [phosphorylates](http://purl.obolibrary.org/obo/RO_0002447) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [phosphorylates](http://purl.obolibrary.org/obo/RO_0002447) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### photon `http://purl.obolibrary.org/obo/CHEBI_30212` +#### Removed +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gamma" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "light quantum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [label](http://www.w3.org/2000/01/rdf-schema#label) "photon" + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:30212" + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00205" + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Light" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "0.0" + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:10581" + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hnu" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14383" + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "*" + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "foton" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Particle of zero charge, zero rest mass, spin quantum number 1, energy hnu and momentum hnu/c (h is the Planck constant, nu the frequency of radiation and c the speed of light), carrier of electromagnetic force." + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "photon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [mass](http://purl.obolibrary.org/obo/chebi/mass) "0.0" + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hnu" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Lichtquant" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [photon](http://purl.obolibrary.org/obo/CHEBI_30212) SubClassOf [boson](http://purl.obolibrary.org/obo/CHEBI_36341) + + + +### photosynthetic cell `http://purl.obolibrary.org/obo/CL_0000628` +#### Removed +- [photosynthetic cell](http://purl.obolibrary.org/obo/CL_0000628) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### physiological role `http://purl.obolibrary.org/obo/CHEBI_52211` +#### Removed +- [physiological role](http://purl.obolibrary.org/obo/CHEBI_52211) [label](http://www.w3.org/2000/01/rdf-schema#label) "physiological role" + +- [physiological role](http://purl.obolibrary.org/obo/CHEBI_52211) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#1_STAR) + +- [physiological role](http://purl.obolibrary.org/obo/CHEBI_52211) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:52211" + +- [physiological role](http://purl.obolibrary.org/obo/CHEBI_52211) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [physiological role](http://purl.obolibrary.org/obo/CHEBI_52211) + +- [physiological role](http://purl.obolibrary.org/obo/CHEBI_52211) SubClassOf [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) + + + +### pituitary gland cell `http://purl.obolibrary.org/obo/CL_2000004` +#### Removed +- [pituitary gland cell](http://purl.obolibrary.org/obo/CL_2000004) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### placental artery `http://purl.obolibrary.org/obo/UBERON_8480007` +#### Removed +- [placental artery](http://purl.obolibrary.org/obo/UBERON_8480007) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](http://orcid.org/0000-0002-0819-0473) + +#### Added +- [placental artery](http://purl.obolibrary.org/obo/UBERON_8480007) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](https://orcid.org/0000-0002-0819-0473) + + +### placental artery endothelium `http://purl.obolibrary.org/obo/UBERON_8480005` +#### Removed +- [placental artery endothelium](http://purl.obolibrary.org/obo/UBERON_8480005) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](http://orcid.org/0000-0002-0819-0473) + +#### Added +- [placental artery endothelium](http://purl.obolibrary.org/obo/UBERON_8480005) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](https://orcid.org/0000-0002-0819-0473) + + +### placental blood `http://purl.obolibrary.org/obo/UBERON_8470000` +#### Removed +- [placental blood](http://purl.obolibrary.org/obo/UBERON_8470000) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-1773-2692](http://orcid.org/0000-0002-1773-2692) + +#### Added +- [placental blood](http://purl.obolibrary.org/obo/UBERON_8470000) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-1773-2692](https://orcid.org/0000-0002-1773-2692) + + +### placental vein `http://purl.obolibrary.org/obo/UBERON_8480008` +#### Removed +- [placental vein](http://purl.obolibrary.org/obo/UBERON_8480008) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](http://orcid.org/0000-0002-0819-0473) + +#### Added +- [placental vein](http://purl.obolibrary.org/obo/UBERON_8480008) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](https://orcid.org/0000-0002-0819-0473) + + +### plant metabolite `http://purl.obolibrary.org/obo/CHEBI_76924` +#### Removed +- [plant metabolite](http://purl.obolibrary.org/obo/CHEBI_76924) [label](http://www.w3.org/2000/01/rdf-schema#label) "plant metabolite" + +- [plant metabolite](http://purl.obolibrary.org/obo/CHEBI_76924) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:75766" + +- [plant metabolite](http://purl.obolibrary.org/obo/CHEBI_76924) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [plant metabolite](http://purl.obolibrary.org/obo/CHEBI_76924) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [plant metabolite](http://purl.obolibrary.org/obo/CHEBI_76924) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:76924" + +- [plant metabolite](http://purl.obolibrary.org/obo/CHEBI_76924) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms." + +- [plant metabolite](http://purl.obolibrary.org/obo/CHEBI_76924) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:76925" + +- [plant metabolite](http://purl.obolibrary.org/obo/CHEBI_76924) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plant secondary metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [plant metabolite](http://purl.obolibrary.org/obo/CHEBI_76924) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plant metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [plant metabolite](http://purl.obolibrary.org/obo/CHEBI_76924) + +- [plant metabolite](http://purl.obolibrary.org/obo/CHEBI_76924) SubClassOf [eukaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75763) + + + +### plasma cell `http://purl.obolibrary.org/obo/CL_0000786` +#### Removed +- [plasma cell](http://purl.obolibrary.org/obo/CL_0000786) EquivalentTo [antibody secreting cell](http://purl.obolibrary.org/obo/CL_0000946) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [cartwheel heterochromatin](http://purl.obolibrary.org/obo/CL_0017508)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [Golgi apparatus](http://purl.obolibrary.org/obo/GO_0005794)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [syndecan-1](http://purl.obolibrary.org/obo/PR_000001935)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0019814)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) + +- [plasma cell](http://purl.obolibrary.org/obo/CL_0000786) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0019814) + +- [plasma cell](http://purl.obolibrary.org/obo/CL_0000786) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613) + +- [plasma cell](http://purl.obolibrary.org/obo/CL_0000786) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +#### Added +- [plasma cell](http://purl.obolibrary.org/obo/CL_0000786) EquivalentTo [antibody secreting cell](http://purl.obolibrary.org/obo/CL_0000946) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [cartwheel heterochromatin](http://purl.obolibrary.org/obo/CL_0017508)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [Golgi apparatus](http://purl.obolibrary.org/obo/GO_0005794)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0019814)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [syndecan-1](http://purl.obolibrary.org/obo/PR_000001935)) + +- [plasma cell](http://purl.obolibrary.org/obo/CL_0000786) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [plasma cell](http://purl.obolibrary.org/obo/CL_0000786) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613) + +- [plasma cell](http://purl.obolibrary.org/obo/CL_0000786) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0019814) + + +### plasma membrane acetate transport `http://purl.obolibrary.org/obo/GO_0006847` +#### Removed +- [plasma membrane acetate transport](http://purl.obolibrary.org/obo/GO_0006847) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [plasma membrane acetate transport](http://purl.obolibrary.org/obo/GO_0006847) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006847" + +- [plasma membrane acetate transport](http://purl.obolibrary.org/obo/GO_0006847) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of acetate across a plasma membrane." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [plasma membrane acetate transport](http://purl.obolibrary.org/obo/GO_0006847) [label](http://www.w3.org/2000/01/rdf-schema#label) "plasma membrane acetate transport" + +- Class: [plasma membrane acetate transport](http://purl.obolibrary.org/obo/GO_0006847) + +- [plasma membrane acetate transport](http://purl.obolibrary.org/obo/GO_0006847) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([results in transport across](http://purl.obolibrary.org/obo/RO_0002342) some [plasma membrane](http://purl.obolibrary.org/obo/GO_0005886)) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089)) + +- [plasma membrane acetate transport](http://purl.obolibrary.org/obo/GO_0006847) SubClassOf [results in transport across](http://purl.obolibrary.org/obo/RO_0002342) some [plasma membrane](http://purl.obolibrary.org/obo/GO_0005886) + +- [plasma membrane acetate transport](http://purl.obolibrary.org/obo/GO_0006847) SubClassOf [acetate transmembrane transport](http://purl.obolibrary.org/obo/GO_0035433) + + + +### plasmablast `http://purl.obolibrary.org/obo/CL_0000980` +#### Removed +- [plasmablast](http://purl.obolibrary.org/obo/CL_0000980) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([produces](http://purl.obolibrary.org/obo/RO_0003000) some [immunoglobulin complex, circulating](http://purl.obolibrary.org/obo/GO_0042571)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [syndecan-1](http://purl.obolibrary.org/obo/PR_000001935)) + +- [plasmablast](http://purl.obolibrary.org/obo/CL_0000980) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [syndecan-1](http://purl.obolibrary.org/obo/PR_000001935) + +- [plasmablast](http://purl.obolibrary.org/obo/CL_0000980) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +#### Added +- [plasmablast](http://purl.obolibrary.org/obo/CL_0000980) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [syndecan-1](http://purl.obolibrary.org/obo/PR_000001935)) and ([produces](http://purl.obolibrary.org/obo/RO_0003000) some [immunoglobulin complex, circulating](http://purl.obolibrary.org/obo/GO_0042571)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) + +- [plasmablast](http://purl.obolibrary.org/obo/CL_0000980) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [syndecan-1](http://purl.obolibrary.org/obo/PR_000001935) + +- [plasmablast](http://purl.obolibrary.org/obo/CL_0000980) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + + +### plasmacytoid dendritic cell, human `http://purl.obolibrary.org/obo/CL_0001058` +#### Removed +- [plasmacytoid dendritic cell, human](http://purl.obolibrary.org/obo/CL_0001058) EquivalentTo [plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000784) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC class II histocompatibility antigen alpha chain DRA](http://purl.obolibrary.org/obo/PR_000002015)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) + +- [plasmacytoid dendritic cell, human](http://purl.obolibrary.org/obo/CL_0001058) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013) + +#### Added +- [plasmacytoid dendritic cell, human](http://purl.obolibrary.org/obo/CL_0001058) EquivalentTo [plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000784) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC class II histocompatibility antigen alpha chain DRA](http://purl.obolibrary.org/obo/PR_000002015)) + +- [plasmacytoid dendritic cell, human](http://purl.obolibrary.org/obo/CL_0001058) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013) + + +### plural term `http://purl.obolibrary.org/obo/uberon/core#PLURAL` + +#### Added +- [plural term](http://purl.obolibrary.org/obo/uberon/core#PLURAL) [label](http://www.w3.org/2000/01/rdf-schema#label) "plural term" + + +### pnictogen `http://purl.obolibrary.org/obo/CHEBI_33300` +#### Removed +- [pnictogen](http://purl.obolibrary.org/obo/CHEBI_33300) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pnictogens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [pnictogen](http://purl.obolibrary.org/obo/CHEBI_33300) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [pnictogen](http://purl.obolibrary.org/obo/CHEBI_33300) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nitrogenoides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [pnictogen](http://purl.obolibrary.org/obo/CHEBI_33300) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "group V elements" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [pnictogen](http://purl.obolibrary.org/obo/CHEBI_33300) [label](http://www.w3.org/2000/01/rdf-schema#label) "pnictogen" + +- [pnictogen](http://purl.obolibrary.org/obo/CHEBI_33300) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33300" + +- [pnictogen](http://purl.obolibrary.org/obo/CHEBI_33300) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nitrogenoideos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [pnictogen](http://purl.obolibrary.org/obo/CHEBI_33300) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [pnictogen](http://purl.obolibrary.org/obo/CHEBI_33300) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pnictogene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [pnictogen](http://purl.obolibrary.org/obo/CHEBI_33300) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "group 15 elements" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [pnictogen](http://purl.obolibrary.org/obo/CHEBI_33300) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth." + +- [pnictogen](http://purl.obolibrary.org/obo/CHEBI_33300) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pnictogenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [pnictogen](http://purl.obolibrary.org/obo/CHEBI_33300) + +- [pnictogen](http://purl.obolibrary.org/obo/CHEBI_33300) SubClassOf [p-block element atom](http://purl.obolibrary.org/obo/CHEBI_33560) + + + +### pnictogen hydride `http://purl.obolibrary.org/obo/CHEBI_35881` +#### Removed +- [pnictogen hydride](http://purl.obolibrary.org/obo/CHEBI_35881) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pnictogen hydrides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [pnictogen hydride](http://purl.obolibrary.org/obo/CHEBI_35881) [label](http://www.w3.org/2000/01/rdf-schema#label) "pnictogen hydride" + +- [pnictogen hydride](http://purl.obolibrary.org/obo/CHEBI_35881) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35881" + +- [pnictogen hydride](http://purl.obolibrary.org/obo/CHEBI_35881) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [pnictogen hydride](http://purl.obolibrary.org/obo/CHEBI_35881) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [pnictogen hydride](http://purl.obolibrary.org/obo/CHEBI_35881) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pnictogen hydride" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [pnictogen hydride](http://purl.obolibrary.org/obo/CHEBI_35881) + +- [pnictogen hydride](http://purl.obolibrary.org/obo/CHEBI_35881) SubClassOf [inorganic hydride](http://purl.obolibrary.org/obo/CHEBI_33242) + +- [pnictogen hydride](http://purl.obolibrary.org/obo/CHEBI_35881) SubClassOf [pnictogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33302) + + + +### pnictogen molecular entity `http://purl.obolibrary.org/obo/CHEBI_33302` +#### Removed +- [pnictogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33302) [label](http://www.w3.org/2000/01/rdf-schema#label) "pnictogen molecular entity" + +- [pnictogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33302) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pnictogen molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [pnictogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33302) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pnictogen molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [pnictogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33302) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pnictogen molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [pnictogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33302) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [pnictogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33302) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [pnictogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33302) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33302" + +- [pnictogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33302) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A p-block molecular entity containing any pnictogen." + +- [pnictogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33302) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pnictogen molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [pnictogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33302) + +- [pnictogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33302) SubClassOf [p-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33675) + +- [pnictogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33302) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [pnictogen](http://purl.obolibrary.org/obo/CHEBI_33300) + + + +### pnictogen oxoacid `http://purl.obolibrary.org/obo/CHEBI_33408` +#### Removed +- [pnictogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33408) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33408" + +- [pnictogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33408) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pnictogen oxoacids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [pnictogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33408) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [pnictogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33408) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [pnictogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33408) [label](http://www.w3.org/2000/01/rdf-schema#label) "pnictogen oxoacid" + +- Class: [pnictogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33408) + +- [pnictogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33408) SubClassOf [pnictogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33302) + +- [pnictogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33408) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [inorganic acid](http://purl.obolibrary.org/obo/CHEBI_138103) + +- [pnictogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33408) SubClassOf [oxoacid](http://purl.obolibrary.org/obo/CHEBI_24833) + + + +### pnictogen oxoanion `http://purl.obolibrary.org/obo/CHEBI_33459` +#### Removed +- [pnictogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33459) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pnictogen oxoanion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [pnictogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33459) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pnictogen oxoanions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [pnictogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33459) [label](http://www.w3.org/2000/01/rdf-schema#label) "pnictogen oxoanion" + +- [pnictogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33459) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [pnictogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33459) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33459" + +- [pnictogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33459) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [pnictogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33459) + +- [pnictogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33459) SubClassOf [oxoanion](http://purl.obolibrary.org/obo/CHEBI_35406) + +- [pnictogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33459) SubClassOf [pnictogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33302) + + + +### poison `http://purl.obolibrary.org/obo/CHEBI_64909` +#### Removed +- [poison](http://purl.obolibrary.org/obo/CHEBI_64909) [label](http://www.w3.org/2000/01/rdf-schema#label) "poison" + +- [poison](http://purl.obolibrary.org/obo/CHEBI_64909) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "poisonous agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [poison](http://purl.obolibrary.org/obo/CHEBI_64909) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "poisonous agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [poison](http://purl.obolibrary.org/obo/CHEBI_64909) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism." + +- [poison](http://purl.obolibrary.org/obo/CHEBI_64909) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "toxic agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [poison](http://purl.obolibrary.org/obo/CHEBI_64909) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Poison" + +- [poison](http://purl.obolibrary.org/obo/CHEBI_64909) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "toxic substances" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [poison](http://purl.obolibrary.org/obo/CHEBI_64909) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "poisonous substance" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [poison](http://purl.obolibrary.org/obo/CHEBI_64909) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "toxic substance" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [poison](http://purl.obolibrary.org/obo/CHEBI_64909) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:64909" + +- [poison](http://purl.obolibrary.org/obo/CHEBI_64909) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "poisons" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [poison](http://purl.obolibrary.org/obo/CHEBI_64909) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [poison](http://purl.obolibrary.org/obo/CHEBI_64909) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [poison](http://purl.obolibrary.org/obo/CHEBI_64909) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "toxic agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [poison](http://purl.obolibrary.org/obo/CHEBI_64909) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "poisonous substances" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [poison](http://purl.obolibrary.org/obo/CHEBI_64909) + +- [poison](http://purl.obolibrary.org/obo/CHEBI_64909) SubClassOf [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) + + + +### polar amino acid `http://purl.obolibrary.org/obo/CHEBI_26167` +#### Removed +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any amino acid whose side chain is capable of forming one or more hydrogen bonds." + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) [mass](http://purl.obolibrary.org/obo/chebi/mass) "74.059" + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "74.02420" + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polar amino-acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "OC(C(*)N)=O" + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:8283" + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polar amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "polar amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:Polar-amino-acids" + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) [label](http://www.w3.org/2000/01/rdf-schema#label) "polar amino acid" + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26167" + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2H4NO2R" + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polar amino-acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12016058" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- Class: [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) SubClassOf [is_tautomer_of](http://purl.obolibrary.org/obo/chebi#is_tautomer_of) some [polar amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_62031) + +- [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) SubClassOf [amino acid](http://purl.obolibrary.org/obo/CHEBI_33709) + + + +### polar amino acid zwitterion `http://purl.obolibrary.org/obo/CHEBI_62031` +#### Removed +- [polar amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_62031) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C(C([O-])=O)(*)[NH3+]" + +- [polar amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_62031) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:62031" + +- [polar amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_62031) [mass](http://purl.obolibrary.org/obo/chebi/mass) "74.059" + +- [polar amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_62031) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#2_STAR) + +- [polar amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_62031) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Zwitterionic form of a polar amino acid having an anionic carboxy group and a protonated amino group." + +- [polar amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_62031) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:Polar-amino-acids" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "SUBMITTER" + +- [polar amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_62031) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a polar amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [polar amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_62031) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [polar amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_62031) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "74.02420" + +- [polar amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_62031) [label](http://www.w3.org/2000/01/rdf-schema#label) "polar amino acid zwitterion" + +- [polar amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_62031) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2H4NO2R" + +- [polar amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_62031) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- Class: [polar amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_62031) + +- [polar amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_62031) SubClassOf [is_tautomer_of](http://purl.obolibrary.org/obo/chebi#is_tautomer_of) some [polar amino acid](http://purl.obolibrary.org/obo/CHEBI_26167) + +- [polar amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_62031) SubClassOf [amino acid zwitterion](http://purl.obolibrary.org/obo/CHEBI_35238) + + + +### polar solvent `http://purl.obolibrary.org/obo/CHEBI_48354` +#### Removed +- [polar solvent](http://purl.obolibrary.org/obo/CHEBI_48354) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds." + +- [polar solvent](http://purl.obolibrary.org/obo/CHEBI_48354) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [polar solvent](http://purl.obolibrary.org/obo/CHEBI_48354) [label](http://www.w3.org/2000/01/rdf-schema#label) "polar solvent" + +- [polar solvent](http://purl.obolibrary.org/obo/CHEBI_48354) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [polar solvent](http://purl.obolibrary.org/obo/CHEBI_48354) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polar solvents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polar solvent](http://purl.obolibrary.org/obo/CHEBI_48354) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:48354" + +- [polar solvent](http://purl.obolibrary.org/obo/CHEBI_48354) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "polar solvent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- Class: [polar solvent](http://purl.obolibrary.org/obo/CHEBI_48354) + +- [polar solvent](http://purl.obolibrary.org/obo/CHEBI_48354) SubClassOf [solvent](http://purl.obolibrary.org/obo/CHEBI_46787) + + + +### polyanionic macromolecule `http://purl.obolibrary.org/obo/CHEBI_53309` +#### Removed +- [polyanionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53309) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polyanions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "SUBMITTER" + +- [polyanionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53309) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A polymer carrying multiple negative charges." + +- [polyanionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53309) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polyanion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polyanionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53309) [label](http://www.w3.org/2000/01/rdf-schema#label) "polyanionic macromolecule" + +- [polyanionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53309) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [polyanionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53309) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [polyanionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53309) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:53309" + +- Class: [polyanionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53309) + +- [polyanionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53309) SubClassOf [ionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53368) + + + +### polyanionic polymer `http://purl.obolibrary.org/obo/CHEBI_61469` +#### Removed +- [polyanionic polymer](http://purl.obolibrary.org/obo/CHEBI_61469) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A polymer, composed of polyanion macromolecules." + +- [polyanionic polymer](http://purl.obolibrary.org/obo/CHEBI_61469) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [polyanionic polymer](http://purl.obolibrary.org/obo/CHEBI_61469) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polyanions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polyanionic polymer](http://purl.obolibrary.org/obo/CHEBI_61469) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:61469" + +- [polyanionic polymer](http://purl.obolibrary.org/obo/CHEBI_61469) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [polyanionic polymer](http://purl.obolibrary.org/obo/CHEBI_61469) [label](http://www.w3.org/2000/01/rdf-schema#label) "polyanionic polymer" + +- [polyanionic polymer](http://purl.obolibrary.org/obo/CHEBI_61469) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polyanion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [polyanionic polymer](http://purl.obolibrary.org/obo/CHEBI_61469) + +- [polyanionic polymer](http://purl.obolibrary.org/obo/CHEBI_61469) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [polyanionic macromolecule](http://purl.obolibrary.org/obo/CHEBI_53309) + +- [polyanionic polymer](http://purl.obolibrary.org/obo/CHEBI_61469) SubClassOf [ionic polymer](http://purl.obolibrary.org/obo/CHEBI_60164) + + + +### polyatomic anion `http://purl.obolibrary.org/obo/CHEBI_33273` +#### Removed +- [polyatomic anion](http://purl.obolibrary.org/obo/CHEBI_33273) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An anion consisting of more than one atom." + +- [polyatomic anion](http://purl.obolibrary.org/obo/CHEBI_33273) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33273" + +- [polyatomic anion](http://purl.obolibrary.org/obo/CHEBI_33273) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [polyatomic anion](http://purl.obolibrary.org/obo/CHEBI_33273) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [polyatomic anion](http://purl.obolibrary.org/obo/CHEBI_33273) [label](http://www.w3.org/2000/01/rdf-schema#label) "polyatomic anion" + +- [polyatomic anion](http://purl.obolibrary.org/obo/CHEBI_33273) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polyatomic anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [polyatomic anion](http://purl.obolibrary.org/obo/CHEBI_33273) + +- [polyatomic anion](http://purl.obolibrary.org/obo/CHEBI_33273) SubClassOf [anion](http://purl.obolibrary.org/obo/CHEBI_22563) + +- [polyatomic anion](http://purl.obolibrary.org/obo/CHEBI_33273) SubClassOf [polyatomic ion](http://purl.obolibrary.org/obo/CHEBI_36358) + + + +### polyatomic cation `http://purl.obolibrary.org/obo/CHEBI_33702` +#### Removed +- [polyatomic cation](http://purl.obolibrary.org/obo/CHEBI_33702) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [polyatomic cation](http://purl.obolibrary.org/obo/CHEBI_33702) [label](http://www.w3.org/2000/01/rdf-schema#label) "polyatomic cation" + +- [polyatomic cation](http://purl.obolibrary.org/obo/CHEBI_33702) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33702" + +- [polyatomic cation](http://purl.obolibrary.org/obo/CHEBI_33702) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polyatomic cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polyatomic cation](http://purl.obolibrary.org/obo/CHEBI_33702) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polyatomic cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [polyatomic cation](http://purl.obolibrary.org/obo/CHEBI_33702) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A cation consisting of more than one atom." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [polyatomic cation](http://purl.obolibrary.org/obo/CHEBI_33702) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [polyatomic cation](http://purl.obolibrary.org/obo/CHEBI_33702) + +- [polyatomic cation](http://purl.obolibrary.org/obo/CHEBI_33702) SubClassOf [polyatomic ion](http://purl.obolibrary.org/obo/CHEBI_36358) + +- [polyatomic cation](http://purl.obolibrary.org/obo/CHEBI_33702) SubClassOf [cation](http://purl.obolibrary.org/obo/CHEBI_36916) + + + +### polyatomic entity `http://purl.obolibrary.org/obo/CHEBI_36357` +#### Removed +- [polyatomic entity](http://purl.obolibrary.org/obo/CHEBI_36357) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36357" + +- [polyatomic entity](http://purl.obolibrary.org/obo/CHEBI_36357) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [polyatomic entity](http://purl.obolibrary.org/obo/CHEBI_36357) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [polyatomic entity](http://purl.obolibrary.org/obo/CHEBI_36357) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any molecular entity consisting of more than one atom." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [polyatomic entity](http://purl.obolibrary.org/obo/CHEBI_36357) [label](http://www.w3.org/2000/01/rdf-schema#label) "polyatomic entity" + +- [polyatomic entity](http://purl.obolibrary.org/obo/CHEBI_36357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polyatomic entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [polyatomic entity](http://purl.obolibrary.org/obo/CHEBI_36357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polyatomic entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [polyatomic entity](http://purl.obolibrary.org/obo/CHEBI_36357) + +- [polyatomic entity](http://purl.obolibrary.org/obo/CHEBI_36357) SubClassOf [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) + +- [polyatomic entity](http://purl.obolibrary.org/obo/CHEBI_36357) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [group](http://purl.obolibrary.org/obo/CHEBI_24433) + + + +### polyatomic ion `http://purl.obolibrary.org/obo/CHEBI_36358` +#### Removed +- [polyatomic ion](http://purl.obolibrary.org/obo/CHEBI_36358) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polyatomic ions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [polyatomic ion](http://purl.obolibrary.org/obo/CHEBI_36358) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [polyatomic ion](http://purl.obolibrary.org/obo/CHEBI_36358) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36358" + +- [polyatomic ion](http://purl.obolibrary.org/obo/CHEBI_36358) [label](http://www.w3.org/2000/01/rdf-schema#label) "polyatomic ion" + +- [polyatomic ion](http://purl.obolibrary.org/obo/CHEBI_36358) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polyatomic ions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polyatomic ion](http://purl.obolibrary.org/obo/CHEBI_36358) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An ion consisting of more than one atom." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [polyatomic ion](http://purl.obolibrary.org/obo/CHEBI_36358) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [polyatomic ion](http://purl.obolibrary.org/obo/CHEBI_36358) + +- [polyatomic ion](http://purl.obolibrary.org/obo/CHEBI_36358) SubClassOf [ion](http://purl.obolibrary.org/obo/CHEBI_24870) + +- [polyatomic ion](http://purl.obolibrary.org/obo/CHEBI_36358) SubClassOf [polyatomic entity](http://purl.obolibrary.org/obo/CHEBI_36357) + + + +### polycyclic compound `http://purl.obolibrary.org/obo/CHEBI_33635` +#### Removed +- [polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33635) [label](http://www.w3.org/2000/01/rdf-schema#label) "polycyclic compound" + +- [polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33635) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33635) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polycyclic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33635) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33635" + +- [polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33635) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33635) + +- [polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_33635) SubClassOf [cyclic compound](http://purl.obolibrary.org/obo/CHEBI_33595) + + + +### polycyclic heteroarene `http://purl.obolibrary.org/obo/CHEBI_38180` +#### Removed +- [polycyclic heteroarene](http://purl.obolibrary.org/obo/CHEBI_38180) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polycyclic heteroarenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [polycyclic heteroarene](http://purl.obolibrary.org/obo/CHEBI_38180) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polycyclic heteroarenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polycyclic heteroarene](http://purl.obolibrary.org/obo/CHEBI_38180) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [polycyclic heteroarene](http://purl.obolibrary.org/obo/CHEBI_38180) [label](http://www.w3.org/2000/01/rdf-schema#label) "polycyclic heteroarene" + +- [polycyclic heteroarene](http://purl.obolibrary.org/obo/CHEBI_38180) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [polycyclic heteroarene](http://purl.obolibrary.org/obo/CHEBI_38180) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:38180" + +- Class: [polycyclic heteroarene](http://purl.obolibrary.org/obo/CHEBI_38180) + +- [polycyclic heteroarene](http://purl.obolibrary.org/obo/CHEBI_38180) SubClassOf [heteroarene](http://purl.obolibrary.org/obo/CHEBI_33833) + + + +### polymer `http://purl.obolibrary.org/obo/CHEBI_60027` +#### Removed +- [polymer](http://purl.obolibrary.org/obo/CHEBI_60027) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [polymer](http://purl.obolibrary.org/obo/CHEBI_60027) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:60027" + +- [polymer](http://purl.obolibrary.org/obo/CHEBI_60027) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [polymer](http://purl.obolibrary.org/obo/CHEBI_60027) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Polymer" + +- [polymer](http://purl.obolibrary.org/obo/CHEBI_60027) [label](http://www.w3.org/2000/01/rdf-schema#label) "polymer" + +- [polymer](http://purl.obolibrary.org/obo/CHEBI_60027) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Polymer" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polymer](http://purl.obolibrary.org/obo/CHEBI_60027) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Kunststoff" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polymer](http://purl.obolibrary.org/obo/CHEBI_60027) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc.." + +- Class: [polymer](http://purl.obolibrary.org/obo/CHEBI_60027) + +- [polymer](http://purl.obolibrary.org/obo/CHEBI_60027) SubClassOf [mixture](http://purl.obolibrary.org/obo/CHEBI_60004) + +- [polymer](http://purl.obolibrary.org/obo/CHEBI_60027) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [macromolecule](http://purl.obolibrary.org/obo/CHEBI_33839) + + + +### polynucleotide `http://purl.obolibrary.org/obo/CHEBI_15986` +#### Removed +- [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Polynucleotide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) [formula](http://purl.obolibrary.org/obo/chebi/formula) "(C5H8O6PR)n.C10H17O10PR2" + +- [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) [label](http://www.w3.org/2000/01/rdf-schema#label) "polynucleotide" + +- [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:15986" + +- [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:8312" + +- [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14859" + +- [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polynucleotides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00419" + +- [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues." + +- [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13672" + +- [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) + +- [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) SubClassOf [nucleobase-containing molecular entity](http://purl.obolibrary.org/obo/CHEBI_61120) + +- [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) SubClassOf [information biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33695) + +- [polynucleotide](http://purl.obolibrary.org/obo/CHEBI_15986) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50319) + + + +### polypeptide `http://purl.obolibrary.org/obo/CHEBI_15841` +#### Removed +- [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "polypeptides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C4H6N2O3R2(C2H2NOR)n" + +- [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14860" + +- [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:8314" + +- [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polipeptido" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) [label](http://www.w3.org/2000/01/rdf-schema#label) "polypeptide" + +- [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Polypeptid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00403" + +- [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:15841" + +- [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Polypeptide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A peptide containing ten or more amino acid residues." + +- Class: [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) + +- [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) SubClassOf [macromolecule](http://purl.obolibrary.org/obo/CHEBI_33839) + +- [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) SubClassOf [peptide](http://purl.obolibrary.org/obo/CHEBI_16670) + + + +### polypyrrole `http://purl.obolibrary.org/obo/CHEBI_38077` +#### Removed +- [polypyrrole](http://purl.obolibrary.org/obo/CHEBI_38077) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [polypyrrole](http://purl.obolibrary.org/obo/CHEBI_38077) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "poly(pyrrole)s" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polypyrrole](http://purl.obolibrary.org/obo/CHEBI_38077) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A compound composed of two or more pyrrole units." + +- [polypyrrole](http://purl.obolibrary.org/obo/CHEBI_38077) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:38077" + +- [polypyrrole](http://purl.obolibrary.org/obo/CHEBI_38077) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polypyrroles" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polypyrrole](http://purl.obolibrary.org/obo/CHEBI_38077) [label](http://www.w3.org/2000/01/rdf-schema#label) "polypyrrole" + +- [polypyrrole](http://purl.obolibrary.org/obo/CHEBI_38077) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "PPys" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polypyrrole](http://purl.obolibrary.org/obo/CHEBI_38077) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [polypyrrole](http://purl.obolibrary.org/obo/CHEBI_38077) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:8538310" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- Class: [polypyrrole](http://purl.obolibrary.org/obo/CHEBI_38077) + +- [polypyrrole](http://purl.obolibrary.org/obo/CHEBI_38077) SubClassOf [organonitrogen heterocyclic compound](http://purl.obolibrary.org/obo/CHEBI_38101) + + + +### polysaccharide `http://purl.obolibrary.org/obo/CHEBI_18154` +#### Removed +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:26205" + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glykan" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glycans" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polisacaridos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Polysaccharide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:18154" + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polisacarido" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00420" + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14864" + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glycan" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glycane" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "polysaccharides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Glykane" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues." + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [label](http://www.w3.org/2000/01/rdf-schema#label) "polysaccharide" + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:8322" + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) SubClassOf [biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33694) + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) SubClassOf [glycan](http://purl.obolibrary.org/obo/CHEBI_167559) + +- [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) SubClassOf [carbohydrate](http://purl.obolibrary.org/obo/CHEBI_16646) + + + +### polysaccharide binding `http://purl.obolibrary.org/obo/GO_0030247` +#### Removed +- [polysaccharide binding](http://purl.obolibrary.org/obo/GO_0030247) SubClassOf [carbohydrate binding](http://purl.obolibrary.org/obo/GO_0030246) + +#### Added +- [polysaccharide binding](http://purl.obolibrary.org/obo/GO_0030247) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### polysaccharide biosynthetic process `http://purl.obolibrary.org/obo/GO_0000271` +#### Removed +- [polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0000271) SubClassOf [carbohydrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0016051) + +- [polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0000271) SubClassOf [macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0009059) + +#### Added +- [polysaccharide biosynthetic process](http://purl.obolibrary.org/obo/GO_0000271) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### polysaccharide catabolic process `http://purl.obolibrary.org/obo/GO_0000272` +#### Removed +- [polysaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0000272) SubClassOf [macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0009057) + +- [polysaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0000272) SubClassOf [carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0016052) + +#### Added +- [polysaccharide catabolic process](http://purl.obolibrary.org/obo/GO_0000272) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### polysaccharide derivative `http://purl.obolibrary.org/obo/CHEBI_65212` +#### Removed +- [polysaccharide derivative](http://purl.obolibrary.org/obo/CHEBI_65212) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:65212" + +- [polysaccharide derivative](http://purl.obolibrary.org/obo/CHEBI_65212) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [polysaccharide derivative](http://purl.obolibrary.org/obo/CHEBI_65212) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [polysaccharide derivative](http://purl.obolibrary.org/obo/CHEBI_65212) [label](http://www.w3.org/2000/01/rdf-schema#label) "polysaccharide derivative" + +- [polysaccharide derivative](http://purl.obolibrary.org/obo/CHEBI_65212) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polysaccharide derivatives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [polysaccharide derivative](http://purl.obolibrary.org/obo/CHEBI_65212) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A carbohydrate derivative that is any derivative of a polysaccharide." + +- Class: [polysaccharide derivative](http://purl.obolibrary.org/obo/CHEBI_65212) + +- [polysaccharide derivative](http://purl.obolibrary.org/obo/CHEBI_65212) SubClassOf [glycan](http://purl.obolibrary.org/obo/CHEBI_167559) + +- [polysaccharide derivative](http://purl.obolibrary.org/obo/CHEBI_65212) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [polysaccharide](http://purl.obolibrary.org/obo/CHEBI_18154) + +- [polysaccharide derivative](http://purl.obolibrary.org/obo/CHEBI_65212) SubClassOf [carbohydrate derivative](http://purl.obolibrary.org/obo/CHEBI_63299) + +- [polysaccharide derivative](http://purl.obolibrary.org/obo/CHEBI_65212) SubClassOf [biomacromolecule](http://purl.obolibrary.org/obo/CHEBI_33694) + + + +### polysaccharide metabolic process `http://purl.obolibrary.org/obo/GO_0005976` +#### Removed +- [polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005976) SubClassOf [macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0043170) + +- [polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005976) SubClassOf [carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0005975) + +#### Added +- [polysaccharide metabolic process](http://purl.obolibrary.org/obo/GO_0005976) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### polysaccharide transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015159` +#### Removed +- [polysaccharide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015159) SubClassOf [carbohydrate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015144) + +- [polysaccharide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015159) SubClassOf [macromolecule transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022884) + +#### Added +- [polysaccharide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015159) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + +### polysaccharide transport `http://purl.obolibrary.org/obo/GO_0015774` +#### Removed +- [polysaccharide transport](http://purl.obolibrary.org/obo/GO_0015774) SubClassOf [carbohydrate transport](http://purl.obolibrary.org/obo/GO_0008643) + +#### Added +- [polysaccharide transport](http://purl.obolibrary.org/obo/GO_0015774) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### positive regulation of CD4 production `http://purl.obolibrary.org/obo/GO_0045224` + +#### Added +- [positive regulation of CD4 production](http://purl.obolibrary.org/obo/GO_0045224) SubClassOf [positive regulation of protein metabolic process](http://purl.obolibrary.org/obo/GO_0051247) + + +### positive regulation of DNA biosynthetic process `http://purl.obolibrary.org/obo/GO_2000573` +#### Removed +- [positive regulation of DNA biosynthetic process](http://purl.obolibrary.org/obo/GO_2000573) SubClassOf [positive regulation of macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0010557) + +- [positive regulation of DNA biosynthetic process](http://purl.obolibrary.org/obo/GO_2000573) SubClassOf [positive regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031328) + +#### Added +- [positive regulation of DNA biosynthetic process](http://purl.obolibrary.org/obo/GO_2000573) SubClassOf [positive regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009891) + + +### positive regulation of DNA catabolic process `http://purl.obolibrary.org/obo/GO_1903626` +#### Removed +- [positive regulation of DNA catabolic process](http://purl.obolibrary.org/obo/GO_1903626) SubClassOf [positive regulation of cellular catabolic process](http://purl.obolibrary.org/obo/GO_0031331) + +#### Added +- [positive regulation of DNA catabolic process](http://purl.obolibrary.org/obo/GO_1903626) SubClassOf [positive regulation of catabolic process](http://purl.obolibrary.org/obo/GO_0009896) + + +### positive regulation of DNA metabolic process `http://purl.obolibrary.org/obo/GO_0051054` +#### Removed +- [positive regulation of DNA metabolic process](http://purl.obolibrary.org/obo/GO_0051054) SubClassOf [positive regulation of nucleobase-containing compound metabolic process](http://purl.obolibrary.org/obo/GO_0045935) + + + +### positive regulation of RNA biosynthetic process `http://purl.obolibrary.org/obo/GO_1902680` +#### Removed +- [positive regulation of RNA biosynthetic process](http://purl.obolibrary.org/obo/GO_1902680) SubClassOf [positive regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031328) + +- [positive regulation of RNA biosynthetic process](http://purl.obolibrary.org/obo/GO_1902680) SubClassOf [positive regulation of macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0010557) + +#### Added +- [positive regulation of RNA biosynthetic process](http://purl.obolibrary.org/obo/GO_1902680) SubClassOf [positive regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009891) + + +### positive regulation of RNA metabolic process `http://purl.obolibrary.org/obo/GO_0051254` +#### Removed +- [positive regulation of RNA metabolic process](http://purl.obolibrary.org/obo/GO_0051254) SubClassOf [positive regulation of macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0010604) + +- [positive regulation of RNA metabolic process](http://purl.obolibrary.org/obo/GO_0051254) SubClassOf [positive regulation of nucleobase-containing compound metabolic process](http://purl.obolibrary.org/obo/GO_0045935) + +#### Added +- [positive regulation of RNA metabolic process](http://purl.obolibrary.org/obo/GO_0051254) SubClassOf [positive regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009893) + + +### positive regulation of acetate catabolic process `http://purl.obolibrary.org/obo/GO_0045754` +#### Removed +- [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of acetate catabolic process" + +- [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of acetate catabolic process" + +- [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "stimulation of acetate catabolic process" + +- [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of acetate catabolism" + +- [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of acetate breakdown" + +- [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0045754" + +- [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of acetate catabolic process" + +- [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of acetate catabolic process" + +- [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of acetate catabolic process" + +- [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of acetate degradation" + +- Class: [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) + +- [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733)) + +- [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733) + +- [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) SubClassOf [positive regulation of cellular catabolic process](http://purl.obolibrary.org/obo/GO_0031331) + +- [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) SubClassOf [positive regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062013) + +- [positive regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045754) SubClassOf [regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045734) + + + +### positive regulation of alcohol biosynthetic process `http://purl.obolibrary.org/obo/GO_1902932` +#### Removed +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of alcohol biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of alcohol formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of alcohol biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "positive regulation of solventogenesis" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of alcohol biosynthetic process" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of alcohol synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of alcohol biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of alcohol synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of alcohol anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of alcohol formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of alcohol anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of alcohol biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23332010" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of alcohol biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of alcohol biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of alcohol synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of alcohol formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902932" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of alcohol formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of alcohol biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of alcohol synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of alcohol biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-04-22T21:55:19Z" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of alcohol anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of alcohol anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of alcohol anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of alcohol formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of alcohol biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of alcohol synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165)) + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) SubClassOf [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) SubClassOf [positive regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009891) + +- [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) SubClassOf [positive regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062013) + + + +### positive regulation of aldosterone biosynthetic process `http://purl.obolibrary.org/obo/GO_0032349` +#### Removed +- [positive regulation of aldosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_0032349) SubClassOf [positive regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902932) + + + +### positive regulation of alkane biosynthetic process `http://purl.obolibrary.org/obo/GO_1901579` +#### Removed +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of alkane synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of alkane anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of alkane biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of alkane formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of alkane formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of alkane biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901579" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of alkane biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of alkane synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "dhl" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of alkane biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of alkane anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of alkane biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of alkane synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of alkane biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of alkane synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of alkane biosynthetic process" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of alkane biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of alkane biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of alkane biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of alkane synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of alkane formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of alkane formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of alkane anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of alkane biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of alkane formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of alkane anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-11-05T21:54:19Z" + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of alkane anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447)) + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) SubClassOf [positive regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031328) + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447) + +- [positive regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901579) SubClassOf [regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901577) + + + +### positive regulation of amide metabolic process `http://purl.obolibrary.org/obo/GO_0034250` +#### Removed +- [positive regulation of amide metabolic process](http://purl.obolibrary.org/obo/GO_0034250) SubClassOf [positive regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051173) + +#### Added +- [positive regulation of amide metabolic process](http://purl.obolibrary.org/obo/GO_0034250) SubClassOf [positive regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009893) + + +### positive regulation of amine metabolic process `http://purl.obolibrary.org/obo/GO_0033240` +#### Removed +- [positive regulation of amine metabolic process](http://purl.obolibrary.org/obo/GO_0033240) SubClassOf [positive regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051173) + +#### Added +- [positive regulation of amine metabolic process](http://purl.obolibrary.org/obo/GO_0033240) SubClassOf [positive regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009893) + + +### positive regulation of amino acid biosynthetic process `http://purl.obolibrary.org/obo/GO_2000284` +#### Removed +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) SubClassOf [positive regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031328) + +#### Added +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) SubClassOf [positive regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009891) + + +### positive regulation of amino acid metabolic process `http://purl.obolibrary.org/obo/GO_0045764` + +#### Added +- [positive regulation of amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0045764) SubClassOf [positive regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051173) + + +### positive regulation of amino acid transport `http://purl.obolibrary.org/obo/GO_0051957` +#### Removed +- [positive regulation of amino acid transport](http://purl.obolibrary.org/obo/GO_0051957) SubClassOf [positive regulation of organic acid transport](http://purl.obolibrary.org/obo/GO_0032892) + + + +### positive regulation of apolipoprotein binding `http://purl.obolibrary.org/obo/GO_2000658` +#### Removed +- [positive regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000658) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000658" + +- [positive regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000658) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000658) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of apolipoprotein binding" + +- [positive regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000658) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-05-02T05:33:46Z" + +- [positive regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000658) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "vk" + +- [positive regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000658) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of apolipoprotein binding." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:BHF" + +- Class: [positive regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000658) + +- [positive regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000658) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185)) + +- [positive regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000658) SubClassOf [positive regulation of protein binding](http://purl.obolibrary.org/obo/GO_0032092) + +- [positive regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000658) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185) + +- [positive regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000658) SubClassOf [regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000656) + + + +### positive regulation of calcium ion transmembrane transport `http://purl.obolibrary.org/obo/GO_1904427` +#### Removed +- [positive regulation of calcium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1904427) SubClassOf [positive regulation of cation transmembrane transport](http://purl.obolibrary.org/obo/GO_1904064) + +#### Added +- [positive regulation of calcium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1904427) SubClassOf [positive regulation of transmembrane transport](http://purl.obolibrary.org/obo/GO_0034764) + + +### positive regulation of calcium ion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_1901021` +#### Removed +- [positive regulation of calcium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901021) SubClassOf [positive regulation of ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0032414) + +#### Added +- [positive regulation of calcium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901021) SubClassOf [positive regulation of transporter activity](http://purl.obolibrary.org/obo/GO_0032411) + + +### positive regulation of calcium ion transport `http://purl.obolibrary.org/obo/GO_0051928` +#### Removed +- [positive regulation of calcium ion transport](http://purl.obolibrary.org/obo/GO_0051928) SubClassOf [positive regulation of monoatomic ion transport](http://purl.obolibrary.org/obo/GO_0043270) + +#### Added +- [positive regulation of calcium ion transport](http://purl.obolibrary.org/obo/GO_0051928) SubClassOf [positive regulation of transport](http://purl.obolibrary.org/obo/GO_0051050) + + +### positive regulation of calcium-mediated signaling involved in cellular response to calcium ion `http://purl.obolibrary.org/obo/GO_1901197` +#### Removed +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any positive regulation of calcium-mediated signaling that is involved in cellular response to calcium ion." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901197" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of calcium-mediated signaling involved in cellular response to calcium ion" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of calcium-mediated signaling involved in cellular response to Ca2+ ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "stimulation of calcium-mediated signaling involved in cellular response to calcium ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "stimulation of calcium-mediated signaling involved in cellular response to Ca2+ ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of calcium-mediated signaling involved in cellular response to calcium ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of calcium-mediated signaling involved in response to calcium ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of calcium-mediated signaling involved in cellular response to Ca2+ ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "al" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of calcium-mediated signalling involved in cellular response to Ca2+ ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of calcium-mediated signaling involved in cellular response to calcium ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of calcium-mediated signalling involved in cellular response to calcium ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of calcium-mediated signaling involved in cellular response to calcium ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-07-27T10:57:56Z" + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) EquivalentTo [positive regulation of calcium-mediated signaling](http://purl.obolibrary.org/obo/GO_0050850) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_0071277)) + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_0071277) + +- [positive regulation of calcium-mediated signaling involved in cellular response to calcium ion](http://purl.obolibrary.org/obo/GO_1901197) SubClassOf [positive regulation of calcium-mediated signaling](http://purl.obolibrary.org/obo/GO_0050850) + + + +### positive regulation of cation channel activity `http://purl.obolibrary.org/obo/GO_2001259` +#### Removed +- [positive regulation of cation channel activity](http://purl.obolibrary.org/obo/GO_2001259) SubClassOf [positive regulation of ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0032414) + +#### Added +- [positive regulation of cation channel activity](http://purl.obolibrary.org/obo/GO_2001259) SubClassOf [positive regulation of transporter activity](http://purl.obolibrary.org/obo/GO_0032411) + + +### positive regulation of cation transmembrane transport `http://purl.obolibrary.org/obo/GO_1904064` +#### Removed +- [positive regulation of cation transmembrane transport](http://purl.obolibrary.org/obo/GO_1904064) SubClassOf [positive regulation of monoatomic ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0034767) + +#### Added +- [positive regulation of cation transmembrane transport](http://purl.obolibrary.org/obo/GO_1904064) SubClassOf [positive regulation of transmembrane transport](http://purl.obolibrary.org/obo/GO_0034764) + + +### positive regulation of cellular carbohydrate metabolic process `http://purl.obolibrary.org/obo/GO_0010676` +#### Removed +- [positive regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010676) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010676) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of cellular carbohydrate metabolic process" + +- [positive regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010676) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that increases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [positive regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010676) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0010676" + +- Class: [positive regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010676) + +- [positive regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010676) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262)) + +- [positive regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010676) SubClassOf [positive regulation of carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0045913) + +- [positive regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010676) SubClassOf [regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010675) + +- [positive regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010676) SubClassOf [positive regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031325) + +- [positive regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010676) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262) + + + +### positive regulation of cellular response to alcohol `http://purl.obolibrary.org/obo/GO_1905959` +#### Removed +- [positive regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905959) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2017-02-22T12:03:16Z" + +- [positive regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905959) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of cellular response to alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905959) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of cellular response to alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905959) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of cellular response to alcohol" + +- [positive regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905959) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of cellular response to alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905959) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905959) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1905959" + +- [positive regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905959) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "hbye" + +- [positive regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905959) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of cellular response to alcohol." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:26434723" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + +- [positive regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905959) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of cellular response to alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [positive regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905959) + +- [positive regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905959) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306)) + +- [positive regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905959) SubClassOf [positive regulation of cellular process](http://purl.obolibrary.org/obo/GO_0048522) + +- [positive regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905959) SubClassOf [regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905957) + +- [positive regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905959) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306) + +- [positive regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905959) SubClassOf [positive regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901421) + + + +### positive regulation of cellular response to oxidative stress `http://purl.obolibrary.org/obo/GO_1900409` +#### Removed +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1900409" + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "up regulation of adaptive response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of adaptive response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of cellular response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "upregulation of adaptive response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of cellular response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of cellular response to oxidative stress" + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-04-20T03:31:16Z" + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "positive regulation of adaptive response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "up-regulation of adaptive response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of cellular response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of cellular response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599)) + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) SubClassOf [regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900407) + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) SubClassOf [positive regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902884) + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) SubClassOf [positive regulation of cellular process](http://purl.obolibrary.org/obo/GO_0048522) + +- [positive regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900409) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599) + + + +### positive regulation of dopamine metabolic process `http://purl.obolibrary.org/obo/GO_0045964` +#### Removed +- [positive regulation of dopamine metabolic process](http://purl.obolibrary.org/obo/GO_0045964) SubClassOf [positive regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051173) + +#### Added +- [positive regulation of dopamine metabolic process](http://purl.obolibrary.org/obo/GO_0045964) SubClassOf [positive regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009893) + + +### positive regulation of ecdysteroid metabolic process `http://purl.obolibrary.org/obo/GO_0045966` +#### Removed +- [positive regulation of ecdysteroid metabolic process](http://purl.obolibrary.org/obo/GO_0045966) SubClassOf [positive regulation of steroid metabolic process](http://purl.obolibrary.org/obo/GO_0045940) + + + +### positive regulation of epinephrine secretion `http://purl.obolibrary.org/obo/GO_0032812` +#### Removed +- [positive regulation of epinephrine secretion](http://purl.obolibrary.org/obo/GO_0032812) SubClassOf [positive regulation of catecholamine secretion](http://purl.obolibrary.org/obo/GO_0033605) + +#### Added +- [positive regulation of epinephrine secretion](http://purl.obolibrary.org/obo/GO_0032812) SubClassOf [positive regulation of secretion](http://purl.obolibrary.org/obo/GO_0051047) + + +### positive regulation of estrogen secretion `http://purl.obolibrary.org/obo/GO_2000863` +#### Removed +- [positive regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000863) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000863" + +- [positive regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000863) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "positive regulation of oestrogen secretion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [positive regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000863) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of estrogen secretion." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:sl" + +- [positive regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000863) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-07-26T08:48:31Z" + +- [positive regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000863) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000863) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "bf" + +- [positive regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000863) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of estrogen secretion" + +- Class: [positive regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000863) + +- [positive regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000863) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [estrogen secretion](http://purl.obolibrary.org/obo/GO_0035937)) + +- [positive regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000863) SubClassOf [regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000861) + +- [positive regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000863) SubClassOf [positive regulation of steroid hormone secretion](http://purl.obolibrary.org/obo/GO_2000833) + +- [positive regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000863) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [estrogen secretion](http://purl.obolibrary.org/obo/GO_0035937) + + + +### positive regulation of fatty acid biosynthetic process `http://purl.obolibrary.org/obo/GO_0045723` +#### Removed +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of fatty acid biosynthetic process" + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of fatty acid anabolism" + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "stimulation of fatty acid biosynthetic process" + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of fatty acid biosynthetic process" + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of fatty acid formation" + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of fatty acid biosynthetic process" + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of fatty acid biosynthesis" + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0045723" + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of fatty acid biosynthetic process" + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of fatty acid synthesis" + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of fatty acid biosynthetic process" + +- Class: [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633)) + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) SubClassOf [regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042304) + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) SubClassOf [positive regulation of lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046889) + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) SubClassOf [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) + +- [positive regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0045723) SubClassOf [positive regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031328) + + + +### positive regulation of fatty acid metabolic process `http://purl.obolibrary.org/obo/GO_0045923` +#### Removed +- [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of fatty acid metabolic process" + +- [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "stimulation of fatty acid metabolic process" + +- [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of fatty acid metabolic process" + +- [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0045923" + +- [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of fatty acid metabolic process" + +- [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of fatty acid metabolic process" + +- [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of fatty acid metabolic process" + +- [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of fatty acid metabolism" + +- Class: [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) + +- [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631)) + +- [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) SubClassOf [regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0019217) + +- [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) SubClassOf [positive regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031325) + +- [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631) + +- [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) SubClassOf [positive regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062013) + +- [positive regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0045923) SubClassOf [positive regulation of lipid metabolic process](http://purl.obolibrary.org/obo/GO_0045834) + + + +### positive regulation of fatty acid transport `http://purl.obolibrary.org/obo/GO_2000193` +#### Removed +- [positive regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000193) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of fatty acid transport" + +- [positive regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000193) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of fatty acid transport." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:BHF" + +- [positive regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000193) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000193) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000193" + +- [positive regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000193) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-10-18T10:37:17Z" + +- [positive regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000193) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "rl" + +- Class: [positive regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000193) + +- [positive regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000193) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908)) + +- [positive regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000193) SubClassOf [positive regulation of lipid transport](http://purl.obolibrary.org/obo/GO_0032370) + +- [positive regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000193) SubClassOf [regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000191) + +- [positive regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000193) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908) + + + +### positive regulation of glucocorticoid catabolic process `http://purl.obolibrary.org/obo/GO_0031951` +#### Removed +- [positive regulation of glucocorticoid catabolic process](http://purl.obolibrary.org/obo/GO_0031951) SubClassOf [positive regulation of lipid catabolic process](http://purl.obolibrary.org/obo/GO_0050996) + + + +### positive regulation of glucose metabolic process `http://purl.obolibrary.org/obo/GO_0010907` +#### Removed +- [positive regulation of glucose metabolic process](http://purl.obolibrary.org/obo/GO_0010907) SubClassOf [positive regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010676) + +- [positive regulation of glucose metabolic process](http://purl.obolibrary.org/obo/GO_0010907) SubClassOf [positive regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062013) + +#### Added +- [positive regulation of glucose metabolic process](http://purl.obolibrary.org/obo/GO_0010907) SubClassOf [positive regulation of carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0045913) + + +### positive regulation of glycogen metabolic process `http://purl.obolibrary.org/obo/GO_0070875` + +#### Added +- [positive regulation of glycogen metabolic process](http://purl.obolibrary.org/obo/GO_0070875) SubClassOf [positive regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031325) + + +### positive regulation of glycoprotein biosynthetic process `http://purl.obolibrary.org/obo/GO_0010560` +#### Removed +- [positive regulation of glycoprotein biosynthetic process](http://purl.obolibrary.org/obo/GO_0010560) SubClassOf [positive regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031328) + + + +### positive regulation of glycoprotein metabolic process `http://purl.obolibrary.org/obo/GO_1903020` +#### Removed +- [positive regulation of glycoprotein metabolic process](http://purl.obolibrary.org/obo/GO_1903020) SubClassOf [positive regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031325) + +- [positive regulation of glycoprotein metabolic process](http://purl.obolibrary.org/obo/GO_1903020) SubClassOf [positive regulation of protein metabolic process](http://purl.obolibrary.org/obo/GO_0051247) + +#### Added +- [positive regulation of glycoprotein metabolic process](http://purl.obolibrary.org/obo/GO_1903020) SubClassOf [positive regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009893) + + +### positive regulation of hyaluronan biosynthetic process `http://purl.obolibrary.org/obo/GO_1900127` +#### Removed +- [positive regulation of hyaluronan biosynthetic process](http://purl.obolibrary.org/obo/GO_1900127) SubClassOf [positive regulation of macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0010557) + +- [positive regulation of hyaluronan biosynthetic process](http://purl.obolibrary.org/obo/GO_1900127) SubClassOf [positive regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051173) + +#### Added +- [positive regulation of hyaluronan biosynthetic process](http://purl.obolibrary.org/obo/GO_1900127) SubClassOf [positive regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009891) + + +### positive regulation of inorganic anion transmembrane transport `http://purl.obolibrary.org/obo/GO_1903797` +#### Removed +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of inorganic anion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of inorganic anion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of transmembrane inorganic anion transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of inorganic anion transmembrane transport" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of inorganic anion transmembrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of inorganic anion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of inorganic anion transmembrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of inorganic anion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "sl" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of inorganic anion transmembrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of inorganic anion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of inorganic anion transmembrane transport." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11336802" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of transmembrane inorganic anion transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of transmembrane inorganic anion transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2015-01-14T21:45:08Z" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of inorganic anion transmembrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1903797" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of transmembrane inorganic anion transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of transmembrane inorganic anion transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661)) + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) SubClassOf [positive regulation of transmembrane transport](http://purl.obolibrary.org/obo/GO_0034764) + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661) + +- [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) SubClassOf [regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903795) + + + +### positive regulation of iron ion transmembrane transport `http://purl.obolibrary.org/obo/GO_0034761` +#### Removed +- [positive regulation of iron ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0034761) SubClassOf [positive regulation of cation transmembrane transport](http://purl.obolibrary.org/obo/GO_1904064) + +#### Added +- [positive regulation of iron ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0034761) SubClassOf [positive regulation of transmembrane transport](http://purl.obolibrary.org/obo/GO_0034764) + + +### positive regulation of iron ion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_1904256` +#### Removed +- [positive regulation of iron ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1904256) SubClassOf [positive regulation of ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0032414) + +#### Added +- [positive regulation of iron ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1904256) SubClassOf [positive regulation of transporter activity](http://purl.obolibrary.org/obo/GO_0032411) + + +### positive regulation of iron ion transport `http://purl.obolibrary.org/obo/GO_0034758` +#### Removed +- [positive regulation of iron ion transport](http://purl.obolibrary.org/obo/GO_0034758) SubClassOf [positive regulation of monoatomic ion transport](http://purl.obolibrary.org/obo/GO_0043270) + +#### Added +- [positive regulation of iron ion transport](http://purl.obolibrary.org/obo/GO_0034758) SubClassOf [positive regulation of transport](http://purl.obolibrary.org/obo/GO_0051050) + + +### positive regulation of isoprenoid metabolic process `http://purl.obolibrary.org/obo/GO_0045828` +#### Removed +- [positive regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045828) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of isoprenoid metabolism" + +- [positive regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045828) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of isoprenoid metabolic process" + +- [positive regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045828) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of isoprenoid metabolic process" + +- [positive regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045828) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of isoprenoid metabolic process" + +- [positive regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045828) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of isoprenoid metabolic process" + +- [positive regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045828) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0045828" + +- [positive regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045828) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of isoprenoid metabolic process" + +- [positive regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045828) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "stimulation of isoprenoid metabolic process" + +- [positive regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045828) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [positive regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045828) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [positive regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045828) + +- [positive regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045828) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720)) + +- [positive regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045828) SubClassOf [regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0019747) + +- [positive regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045828) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) + +- [positive regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045828) SubClassOf [positive regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031325) + +- [positive regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045828) SubClassOf [positive regulation of lipid metabolic process](http://purl.obolibrary.org/obo/GO_0045834) + + + +### positive regulation of juvenile hormone biosynthetic process `http://purl.obolibrary.org/obo/GO_0045969` +#### Removed +- [positive regulation of juvenile hormone biosynthetic process](http://purl.obolibrary.org/obo/GO_0045969) SubClassOf [positive regulation of lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046889) + + + +### positive regulation of juvenile hormone catabolic process `http://purl.obolibrary.org/obo/GO_0045971` +#### Removed +- [positive regulation of juvenile hormone catabolic process](http://purl.obolibrary.org/obo/GO_0045971) SubClassOf [positive regulation of cellular catabolic process](http://purl.obolibrary.org/obo/GO_0031331) + +- [positive regulation of juvenile hormone catabolic process](http://purl.obolibrary.org/obo/GO_0045971) SubClassOf [positive regulation of lipid catabolic process](http://purl.obolibrary.org/obo/GO_0050996) + +#### Added +- [positive regulation of juvenile hormone catabolic process](http://purl.obolibrary.org/obo/GO_0045971) SubClassOf [positive regulation of catabolic process](http://purl.obolibrary.org/obo/GO_0009896) + + +### positive regulation of juvenile hormone metabolic process `http://purl.obolibrary.org/obo/GO_0045929` +#### Removed +- [positive regulation of juvenile hormone metabolic process](http://purl.obolibrary.org/obo/GO_0045929) SubClassOf [positive regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0045828) + + + +### positive regulation of juvenile hormone secretion `http://purl.obolibrary.org/obo/GO_0045973` +#### Removed +- [positive regulation of juvenile hormone secretion](http://purl.obolibrary.org/obo/GO_0045973) SubClassOf [positive regulation of lipid transport](http://purl.obolibrary.org/obo/GO_0032370) + + + +### positive regulation of lipoprotein metabolic process `http://purl.obolibrary.org/obo/GO_0050747` +#### Removed +- [positive regulation of lipoprotein metabolic process](http://purl.obolibrary.org/obo/GO_0050747) SubClassOf [positive regulation of protein metabolic process](http://purl.obolibrary.org/obo/GO_0051247) + + + +### positive regulation of lipoprotein transport `http://purl.obolibrary.org/obo/GO_0140077` +#### Removed +- [positive regulation of lipoprotein transport](http://purl.obolibrary.org/obo/GO_0140077) SubClassOf [positive regulation of protein transport](http://purl.obolibrary.org/obo/GO_0051222) + +#### Added +- [positive regulation of lipoprotein transport](http://purl.obolibrary.org/obo/GO_0140077) SubClassOf [positive regulation of transport](http://purl.obolibrary.org/obo/GO_0051050) + + +### positive regulation of nitric oxide biosynthetic process `http://purl.obolibrary.org/obo/GO_0045429` + +#### Added +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) SubClassOf [positive regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051173) + + +### positive regulation of nitric oxide metabolic process `http://purl.obolibrary.org/obo/GO_1904407` +#### Removed +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) SubClassOf [positive regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051173) + +#### Added +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) SubClassOf [positive regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009893) + + +### positive regulation of peptide hormone processing `http://purl.obolibrary.org/obo/GO_0060569` +#### Removed +- [positive regulation of peptide hormone processing](http://purl.obolibrary.org/obo/GO_0060569) SubClassOf [positive regulation of amide metabolic process](http://purl.obolibrary.org/obo/GO_0034250) + + + +### positive regulation of phagocytosis `http://purl.obolibrary.org/obo/GO_0050766` +#### Removed +- [positive regulation of phagocytosis](http://purl.obolibrary.org/obo/GO_0050766) SubClassOf [positive regulation of transport](http://purl.obolibrary.org/obo/GO_0051050) + +#### Added +- [positive regulation of phagocytosis](http://purl.obolibrary.org/obo/GO_0050766) SubClassOf [positive regulation of endocytosis](http://purl.obolibrary.org/obo/GO_0045807) + + +### positive regulation of phosphate metabolic process `http://purl.obolibrary.org/obo/GO_0045937` +#### Removed +- [positive regulation of phosphate metabolic process](http://purl.obolibrary.org/obo/GO_0045937) SubClassOf [positive regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010562) + +#### Added +- [positive regulation of phosphate metabolic process](http://purl.obolibrary.org/obo/GO_0045937) SubClassOf [positive regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009893) + + +### positive regulation of phosphate transmembrane transport `http://purl.obolibrary.org/obo/GO_2000187` +#### Removed +- [positive regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000187) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "vw" + +- [positive regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000187) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of phosphate transmembrane transport" + +- [positive regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000187) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of phosphate membrane transport" + +- [positive regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000187) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [positive regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000187) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000187" + +- [positive regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000187) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-10-15T11:33:10Z" + +- [positive regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000187) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [positive regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000187) + +- [positive regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000187) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435)) + +- [positive regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000187) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435) + +- [positive regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000187) SubClassOf [regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000185) + +- [positive regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000187) SubClassOf [positive regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903797) + + + +### positive regulation of phosphorus metabolic process `http://purl.obolibrary.org/obo/GO_0010562` +#### Removed +- [positive regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010562) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0010562" + +- [positive regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010562) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [positive regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010562) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of phosphorus metabolic process" + +- [positive regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010562) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [positive regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010562) + +- [positive regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010562) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0006793)) + +- [positive regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010562) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0006793) + +- [positive regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010562) SubClassOf [regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0051174) + +- [positive regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0010562) SubClassOf [positive regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031325) + + + +### positive regulation of progesterone biosynthetic process `http://purl.obolibrary.org/obo/GO_2000184` +#### Removed +- [positive regulation of progesterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000184) SubClassOf [positive regulation of steroid biosynthetic process](http://purl.obolibrary.org/obo/GO_0010893) + +- [positive regulation of progesterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000184) SubClassOf [positive regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062013) + +- [positive regulation of progesterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000184) SubClassOf [positive regulation of hormone biosynthetic process](http://purl.obolibrary.org/obo/GO_0046886) + +#### Added +- [positive regulation of progesterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000184) SubClassOf [positive regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009891) + + +### positive regulation of protein metabolic process `http://purl.obolibrary.org/obo/GO_0051247` +#### Removed +- [positive regulation of protein metabolic process](http://purl.obolibrary.org/obo/GO_0051247) SubClassOf [positive regulation of macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0010604) + +- [positive regulation of protein metabolic process](http://purl.obolibrary.org/obo/GO_0051247) SubClassOf [positive regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051173) + +#### Added +- [positive regulation of protein metabolic process](http://purl.obolibrary.org/obo/GO_0051247) SubClassOf [positive regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009893) + + +### positive regulation of protein modification process `http://purl.obolibrary.org/obo/GO_0031401` + +#### Added +- [positive regulation of protein modification process](http://purl.obolibrary.org/obo/GO_0031401) SubClassOf [positive regulation of macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0010604) + + +### positive regulation of proteoglycan biosynthetic process `http://purl.obolibrary.org/obo/GO_1902730` +#### Removed +- [positive regulation of proteoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_1902730) SubClassOf [positive regulation of glycoprotein biosynthetic process](http://purl.obolibrary.org/obo/GO_0010560) + +#### Added +- [positive regulation of proteoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_1902730) SubClassOf [positive regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009891) + + +### positive regulation of reactive oxygen species biosynthetic process `http://purl.obolibrary.org/obo/GO_1903428` +#### Removed +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "bf" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "activation of ROS generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of reactive oxygen species biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "positive regulation of ROS formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of reactive oxygen species biosynthetic process" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of reactive oxygen species biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "up regulation of ROS generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "up-regulation of reactive oxygen species generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "activation of reactive oxygen species generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of reactive oxygen species synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of reactive oxygen species synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-09-11T10:02:05Z" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of reactive oxygen species biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of reactive oxygen species synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of reactive oxygen species biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "upregulation of ROS generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of reactive oxygen species formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "upregulation of ROS formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "up regulation of ROS formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "positive regulation of ROS generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "positive regulation of reactive oxygen species generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of reactive oxygen species formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of reactive oxygen species synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "activation of ROS formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of reactive oxygen species synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of reactive oxygen species anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of reactive oxygen species biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of reactive oxygen species formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1903428" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of reactive oxygen species biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "upregulation of reactive oxygen species generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "up regulation of reactive oxygen species generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of reactive oxygen species biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of reactive oxygen species anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of reactive oxygen species anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of reactive oxygen species formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of reactive oxygen species biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "up-regulation of ROS generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "up-regulation of ROS formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of reactive oxygen species formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of reactive oxygen species anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of reactive oxygen species biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of reactive oxygen species anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:bf" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24252804" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:PARL" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + +- Class: [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409)) + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) SubClassOf [positive regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000379) + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) SubClassOf [positive regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009891) + +- [positive regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903428) SubClassOf [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) + + + +### positive regulation of reactive oxygen species metabolic process `http://purl.obolibrary.org/obo/GO_2000379` +#### Removed +- [positive regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000379) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-02-11T02:06:57Z" + +- [positive regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000379) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000379" + +- [positive regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000379) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000379) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- [positive regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000379) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [positive regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000379) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of reactive oxygen species metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [positive regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000379) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of ROS metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [positive regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000379) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of reactive oxygen species metabolic process" + +- Class: [positive regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000379) + +- [positive regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000379) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593)) + +- [positive regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000379) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593) + +- [positive regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000379) SubClassOf [regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000377) + +- [positive regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000379) SubClassOf [positive regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031325) + + + +### positive regulation of response to acetate `http://purl.obolibrary.org/obo/GO_1901459` +#### Removed +- [positive regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901459) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of response to acetate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901459) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [positive regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901459) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of response to acetate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901459) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-02T14:26:34Z" + +- [positive regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901459) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of response to acetate" + +- [positive regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901459) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of response to acetate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901459) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901459" + +- [positive regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901459) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901459) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of response to acetate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901459) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of response to acetate." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- Class: [positive regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901459) + +- [positive regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901459) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [response to acetate](http://purl.obolibrary.org/obo/GO_0010034)) + +- [positive regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901459) SubClassOf [regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901457) + +- [positive regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901459) SubClassOf [positive regulation of response to stimulus](http://purl.obolibrary.org/obo/GO_0048584) + +- [positive regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901459) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [response to acetate](http://purl.obolibrary.org/obo/GO_0010034) + + + +### positive regulation of response to alcohol `http://purl.obolibrary.org/obo/GO_1901421` +#### Removed +- [positive regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901421) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-01T16:53:42Z" + +- [positive regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901421) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901421) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of response to alcohol" + +- [positive regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901421) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [positive regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901421) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of response to alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901421) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901421" + +- [positive regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901421) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of response to alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901421) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of response to alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901421) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of response to alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901421) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of response to alcohol." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- Class: [positive regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901421) + +- [positive regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901421) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305)) + +- [positive regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901421) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) + +- [positive regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901421) SubClassOf [regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901419) + +- [positive regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901421) SubClassOf [positive regulation of response to stimulus](http://purl.obolibrary.org/obo/GO_0048584) + + + +### positive regulation of response to formic acid `http://purl.obolibrary.org/obo/GO_1901462` +#### Removed +- [positive regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901462) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of response to formic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901462) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of response to formic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901462) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [positive regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901462) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of response to formic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901462) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of response to formic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901462) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901462" + +- [positive regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901462) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901462) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-02T14:29:20Z" + +- [positive regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901462) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of response to formic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [positive regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901462) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of response to formic acid" + +- Class: [positive regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901462) + +- [positive regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901462) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [response to formic acid](http://purl.obolibrary.org/obo/GO_1901425)) + +- [positive regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901462) SubClassOf [positive regulation of response to stimulus](http://purl.obolibrary.org/obo/GO_0048584) + +- [positive regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901462) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [response to formic acid](http://purl.obolibrary.org/obo/GO_1901425) + +- [positive regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901462) SubClassOf [regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901460) + + + +### positive regulation of response to oxidative stress `http://purl.obolibrary.org/obo/GO_1902884` +#### Removed +- [positive regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902884) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902884) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of response to oxidative stress." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16899554" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:kmv" + +- [positive regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902884) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902884" + +- [positive regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902884) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902884) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902884) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-04-03T20:30:47Z" + +- [positive regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902884) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902884) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "kmv" + +- [positive regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902884) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of response to oxidative stress" + +- [positive regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902884) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [positive regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902884) + +- [positive regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902884) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [response to oxidative stress](http://purl.obolibrary.org/obo/GO_0006979)) + +- [positive regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902884) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [response to oxidative stress](http://purl.obolibrary.org/obo/GO_0006979) + +- [positive regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902884) SubClassOf [positive regulation of response to stimulus](http://purl.obolibrary.org/obo/GO_0048584) + +- [positive regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902884) SubClassOf [regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902882) + + + +### positive regulation of response to reactive oxygen species `http://purl.obolibrary.org/obo/GO_1901033` +#### Removed +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of response to ROI" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of response to reactive oxidative species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of response to ROS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of response to reactive oxygen species" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of response to active oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of response to active oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of response to active oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of response to AOS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of response to ROS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of response to reactive oxidative species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of response to reactive oxygen intermediate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of response to reactive oxygen intermediate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of response to ROI" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of response to reactive oxidative species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of response to reactive oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of response to AOS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of response to ROI" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of response to reactive oxygen intermediate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of response to ROI" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of response to ROS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of response to reactive oxidative species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of response to reactive oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of response to reactive oxygen intermediate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of response to active oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of response to AOS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of response to reactive oxygen intermediate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "kmv" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of response to reactive oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of response to reactive oxidative species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of response to AOS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of response to ROI" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-06-20T07:47:35Z" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901033" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of response to active oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of response to ROS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of response to ROS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of response to reactive oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of response to AOS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:kmv" + +- Class: [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302)) + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) SubClassOf [positive regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902884) + +- [positive regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901033) SubClassOf [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) + + + +### positive regulation of secondary metabolite biosynthetic process `http://purl.obolibrary.org/obo/GO_1900378` +#### Removed +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1900378" + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of secondary metabolite biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of secondary metabolite biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of secondary metabolite biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of secondary metabolite biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:di" + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of secondary metabolite biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of secondary metabolite biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-04-17T01:55:41Z" + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of secondary metabolite biosynthetic process" + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of secondary metabolite biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "di" + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of secondary metabolite biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of secondary metabolite biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550)) + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550) + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) SubClassOf [regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900376) + +- [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) SubClassOf [positive regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009891) + + + +### positive regulation of sodium ion transmembrane transport `http://purl.obolibrary.org/obo/GO_1902307` +#### Removed +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of sodium ion transmembrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of sodium ion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of sodium ion transmembrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of sodium ion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of sodium ion transmembrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "rl" + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of sodium ion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of sodium ion transmembrane transport" + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of sodium ion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_cardiac_conduct_nov11" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:rl" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:BHF" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18591664" + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902307" + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of sodium ion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of sodium ion transmembrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2013-07-18T13:34:18Z" + +- Class: [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725)) + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725) + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) SubClassOf [regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902305) + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) SubClassOf [positive regulation of cation transmembrane transport](http://purl.obolibrary.org/obo/GO_1904064) + +- [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) SubClassOf [positive regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010765) + + + +### positive regulation of sodium ion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_2000651` +#### Removed +- [positive regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000651) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of sodium transporter activity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [positive regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000651) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of sodium ion transmembrane transporter activity" + +- [positive regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000651) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [positive regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000651) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-04-28T08:43:00Z" + +- [positive regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000651) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "yaf" + +- [positive regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000651) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000651" + +- [positive regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000651) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [positive regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000651) + +- [positive regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000651) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081)) + +- [positive regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000651) SubClassOf [positive regulation of ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0032414) + +- [positive regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000651) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081) + +- [positive regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000651) SubClassOf [positive regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902307) + +- [positive regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000651) SubClassOf [regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000649) + + + +### positive regulation of sodium ion transport `http://purl.obolibrary.org/obo/GO_0010765` +#### Removed +- [positive regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010765) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [positive regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010765) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010765) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0010765" + +- [positive regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010765) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of sodium ion transport" + +- Class: [positive regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010765) + +- [positive regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010765) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814)) + +- [positive regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010765) SubClassOf [regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0002028) + +- [positive regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010765) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) + +- [positive regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0010765) SubClassOf [positive regulation of monoatomic ion transport](http://purl.obolibrary.org/obo/GO_0043270) + + + +### positive regulation of sphingolipid biosynthetic process `http://purl.obolibrary.org/obo/GO_0090154` +#### Removed +- [positive regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090154) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tb" + +- [positive regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090154) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of sphingolipid biosynthetic process" + +- [positive regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090154) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090154) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0090154" + +- [positive regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090154) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ascb_2009" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [positive regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090154) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2009-12-08T03:27:33Z" + +- Class: [positive regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090154) + +- [positive regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090154) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148)) + +- [positive regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090154) SubClassOf [positive regulation of lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046889) + +- [positive regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090154) SubClassOf [regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090153) + +- [positive regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090154) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) + +- [positive regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090154) SubClassOf [positive regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031328) + +- [positive regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090154) SubClassOf [positive regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051173) + + + +### positive regulation of sulfur metabolic process `http://purl.obolibrary.org/obo/GO_0051176` +#### Removed +- [positive regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051176) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of sulphur metabolism" + +- [positive regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051176) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of sulfur metabolic process" + +- [positive regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051176) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of sulfur metabolic process" + +- [positive regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051176) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of sulfur metabolic process" + +- [positive regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051176) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of sulfur metabolic process" + +- [positive regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051176) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "stimulation of sulfur metabolic process" + +- [positive regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051176) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of sulphur metabolic process" + +- [positive regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051176) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of sulfur metabolic process" + +- [positive regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051176) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051176) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0051176" + +- [positive regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051176) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of sulfur metabolism" + +- [positive regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051176) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- Class: [positive regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051176) + +- [positive regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051176) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790)) + +- [positive regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051176) SubClassOf [positive regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031325) + +- [positive regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051176) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) + +- [positive regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0051176) SubClassOf [regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0042762) + + + +### positive regulation of superoxide anion generation `http://purl.obolibrary.org/obo/GO_0032930` +#### Removed +- [positive regulation of superoxide anion generation](http://purl.obolibrary.org/obo/GO_0032930) SubClassOf [positive regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000379) + +#### Added +- [positive regulation of superoxide anion generation](http://purl.obolibrary.org/obo/GO_0032930) SubClassOf [positive regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009893) + + +### positive regulation of testosterone secretion `http://purl.obolibrary.org/obo/GO_2000845` +#### Removed +- [positive regulation of testosterone secretion](http://purl.obolibrary.org/obo/GO_2000845) SubClassOf [positive regulation of lipid transport](http://purl.obolibrary.org/obo/GO_0032370) + + + +### positive regulation of tetrapyrrole biosynthetic process `http://purl.obolibrary.org/obo/GO_1901465` +#### Removed +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of tetrapyrrole formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of tetrapyrrole anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901465" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of tetrapyrrole formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of tetrapyrrole anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of tetrapyrrole synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of tetrapyrrole biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of tetrapyrrole biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of tetrapyrrole formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of tetrapyrrole biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of tetrapyrrole biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of tetrapyrrole formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of tetrapyrrole synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of tetrapyrrole anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of tetrapyrrole synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of tetrapyrrole anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of tetrapyrrole biosynthetic process" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of tetrapyrrole biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of tetrapyrrole synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of tetrapyrrole formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of tetrapyrrole biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of tetrapyrrole synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-02T14:35:43Z" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of tetrapyrrole anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of tetrapyrrole biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of tetrapyrrole biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of tetrapyrrole biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014)) + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) SubClassOf [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) SubClassOf [positive regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031328) + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) SubClassOf [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) + +- [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) + + + +### positive regulation of tetrapyrrole biosynthetic process from glutamate `http://purl.obolibrary.org/obo/GO_1901412` +#### Removed +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of tetrapyrrole biosynthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of tetrapyrrole anabolism from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of tetrapyrrole biosynthetic process from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of tetrapyrrole formation from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of tetrapyrrole biosynthetic process from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of tetrapyrrole biosynthetic process from glutamate" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of tetrapyrrole synthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of tetrapyrrole anabolism from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of tetrapyrrole anabolism from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of tetrapyrrole formation from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of tetrapyrrole formation from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of tetrapyrrole biosynthetic process from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of tetrapyrrole biosynthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of tetrapyrrole anabolism from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of tetrapyrrole formation from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of tetrapyrrole biosynthetic process from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of tetrapyrrole biosynthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of tetrapyrrole anabolism from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of tetrapyrrole biosynthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of tetrapyrrole biosynthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of tetrapyrrole synthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-01T16:22:21Z" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of tetrapyrrole synthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of tetrapyrrole synthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of tetrapyrrole synthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of tetrapyrrole formation from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901412" + +- Class: [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526)) + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) SubClassOf [regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901410) + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526) + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) SubClassOf [positive regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901465) + +- [positive regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901412) SubClassOf [positive regulation of glutamate metabolic process](http://purl.obolibrary.org/obo/GO_2000213) + + + +### positive regulation of tetrapyrrole catabolic process `http://purl.obolibrary.org/obo/GO_1901406` +#### Removed +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of tetrapyrrole catabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of tetrapyrrole degradation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of tetrapyrrole catabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of tetrapyrrole degradation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of tetrapyrrole catabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of tetrapyrrole breakdown" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901406" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of tetrapyrrole breakdown" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of tetrapyrrole catabolic process" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of tetrapyrrole catabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of tetrapyrrole catabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of tetrapyrrole catabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of tetrapyrrole catabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of tetrapyrrole breakdown" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of tetrapyrrole degradation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of tetrapyrrole catabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of tetrapyrrole breakdown" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of tetrapyrrole degradation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of tetrapyrrole breakdown" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of tetrapyrrole catabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of tetrapyrrole degradation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-01T14:39:40Z" + +- Class: [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015)) + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) SubClassOf [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) SubClassOf [positive regulation of cellular catabolic process](http://purl.obolibrary.org/obo/GO_0031331) + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) SubClassOf [regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901404) + +- [positive regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901406) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) + + + +### positive regulation of tetrapyrrole metabolic process `http://purl.obolibrary.org/obo/GO_1901403` +#### Removed +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of tetrapyrrole metabolic process" + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of tetrapyrrole metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "activation of tetrapyrrole metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of tetrapyrrole metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of tetrapyrrole metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of tetrapyrrole metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of tetrapyrrole metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of tetrapyrrole metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-01T14:35:29Z" + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of tetrapyrrole metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901403" + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of tetrapyrrole metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013)) + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) SubClassOf [regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901401) + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) SubClassOf [positive regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031325) + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) SubClassOf [positive regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051173) + +- [positive regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901403) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) + + + +### positive regulation of translation `http://purl.obolibrary.org/obo/GO_0045727` +#### Removed +- [positive regulation of translation](http://purl.obolibrary.org/obo/GO_0045727) SubClassOf [positive regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031328) + +- [positive regulation of translation](http://purl.obolibrary.org/obo/GO_0045727) SubClassOf [positive regulation of amide metabolic process](http://purl.obolibrary.org/obo/GO_0034250) + + + +### positive regulation of translation in response to oxidative stress `http://purl.obolibrary.org/obo/GO_0032939` +#### Removed +- [positive regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032939) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of translation in response to oxidative stress" + +- [positive regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032939) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of translation in response to oxidative stress" + +- [positive regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032939) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of translation in response to oxidative stress" + +- [positive regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032939) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [positive regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032939) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0032939" + +- [positive regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032939) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "stimulation of translation in response to oxidative stress" + +- [positive regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032939) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of translation in response to oxidative stress" + +- [positive regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032939) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032939) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of translation in response to oxidative stress" + +- Class: [positive regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032939) + +- [positive regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032939) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599)) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [translation](http://purl.obolibrary.org/obo/GO_0006412)) + +- [positive regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032939) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599) + +- [positive regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0032939) SubClassOf [positive regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032056) + + + +### positive regulation of translation in response to stress `http://purl.obolibrary.org/obo/GO_0032056` +#### Removed +- [positive regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032056) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of translation in response to stress" + +- [positive regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032056) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032056) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "stimulation of translation in response to stress" + +- [positive regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032056) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of translation in response to stress" + +- [positive regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032056) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of translation in response to stress" + +- [positive regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032056) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0032056" + +- [positive regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032056) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of translation in response to stress" + +- [positive regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032056) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [positive regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032056) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of translation in response to stress" + +- Class: [positive regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032056) + +- [positive regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032056) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [cellular response to stress](http://purl.obolibrary.org/obo/GO_0033554)) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [translation](http://purl.obolibrary.org/obo/GO_0006412)) + +- [positive regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032056) SubClassOf [positive regulation of translation](http://purl.obolibrary.org/obo/GO_0045727) + +- [positive regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032056) SubClassOf [regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0043555) + + + +### positive regulation of translational initiation `http://purl.obolibrary.org/obo/GO_0045948` + +#### Added +- [positive regulation of translational initiation](http://purl.obolibrary.org/obo/GO_0045948) SubClassOf [positive regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031325) + + +### positive regulation of voltage-gated calcium channel activity `http://purl.obolibrary.org/obo/GO_1901387` +#### Removed +- [positive regulation of voltage-gated calcium channel activity](http://purl.obolibrary.org/obo/GO_1901387) SubClassOf [positive regulation of cation channel activity](http://purl.obolibrary.org/obo/GO_2001259) + + + +### positively regulated by `http://purl.obolibrary.org/obo/RO_0002336` +#### Removed +- [positively regulated by](http://purl.obolibrary.org/obo/RO_0002336) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [positively regulated by](http://purl.obolibrary.org/obo/RO_0002336) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### positively regulates `http://purl.obolibrary.org/obo/RO_0002213` +#### Removed +- [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall"@en + +#### Added +- [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### pre-B-II cell `http://purl.obolibrary.org/obo/CL_0000955` +#### Removed +- [pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000955) EquivalentTo [precursor B cell](http://purl.obolibrary.org/obo/CL_0000817) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [immunoglobulin heavy chain V-D-J recombination](http://purl.obolibrary.org/obo/GO_0071707)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [DNA nucleotidylexotransferase](http://purl.obolibrary.org/obo/PR_000006611)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) + +- [pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000955) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [DNA nucleotidylexotransferase](http://purl.obolibrary.org/obo/PR_000006611) + +- [pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000955) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + +#### Added +- [pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000955) EquivalentTo [precursor B cell](http://purl.obolibrary.org/obo/CL_0000817) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [DNA nucleotidylexotransferase](http://purl.obolibrary.org/obo/PR_000006611)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [immunoglobulin heavy chain V-D-J recombination](http://purl.obolibrary.org/obo/GO_0071707)) + +- [pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000955) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [DNA nucleotidylexotransferase](http://purl.obolibrary.org/obo/PR_000006611) + +- [pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000955) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003) + + +### pre-conventional dendritic cell `http://purl.obolibrary.org/obo/CL_0002010` +#### Removed +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) EquivalentTo [hematopoietic lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0002031) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [tyrosine-protein phosphatase non-receptor type substrate 1](http://purl.obolibrary.org/obo/PR_000001968)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +#### Added +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) EquivalentTo [hematopoietic lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0002031) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [tyrosine-protein phosphatase non-receptor type substrate 1](http://purl.obolibrary.org/obo/PR_000001968)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001)) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 76 (mouse)](http://purl.obolibrary.org/obo/PR_000002981) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + + +### preBCR-negative large pre-B-II cell `http://purl.obolibrary.org/obo/CL_0000953` +#### Removed +- [preBCR-negative large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000953) EquivalentTo [large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000957) and ([has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [immunoglobulin light chain V-J recombination](http://purl.obolibrary.org/obo/GO_0071708)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [pre-B cell receptor complex](http://purl.obolibrary.org/obo/GO_0035369)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [immunoglobulin iota chain](http://purl.obolibrary.org/obo/PR_000001858)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [immunoglobulin lambda-like polypeptide 1](http://purl.obolibrary.org/obo/PR_000001859)) + +- [preBCR-negative large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000953) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [pre-B cell receptor complex](http://purl.obolibrary.org/obo/GO_0035369) + +- [preBCR-negative large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000953) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [immunoglobulin light chain V-J recombination](http://purl.obolibrary.org/obo/GO_0071708) + +- [preBCR-negative large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000953) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [immunoglobulin iota chain](http://purl.obolibrary.org/obo/PR_000001858) + +- [preBCR-negative large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000953) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [immunoglobulin lambda-like polypeptide 1](http://purl.obolibrary.org/obo/PR_000001859) + +#### Added +- [preBCR-negative large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000953) EquivalentTo [large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000957) and ([has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [immunoglobulin light chain V-J recombination](http://purl.obolibrary.org/obo/GO_0071708)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [pre-B cell receptor complex](http://purl.obolibrary.org/obo/GO_0035369)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [immunoglobulin iota chain](http://purl.obolibrary.org/obo/PR_000001858)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [immunoglobulin lambda-like polypeptide 1](http://purl.obolibrary.org/obo/PR_000001859)) + +- [preBCR-negative large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000953) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [immunoglobulin lambda-like polypeptide 1](http://purl.obolibrary.org/obo/PR_000001859) + +- [preBCR-negative large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000953) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [immunoglobulin light chain V-J recombination](http://purl.obolibrary.org/obo/GO_0071708) + +- [preBCR-negative large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000953) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [pre-B cell receptor complex](http://purl.obolibrary.org/obo/GO_0035369) + +- [preBCR-negative large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000953) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [immunoglobulin iota chain](http://purl.obolibrary.org/obo/PR_000001858) + + +### preBCR-positive large pre-B-II cell `http://purl.obolibrary.org/obo/CL_0000952` +#### Removed +- [preBCR-positive large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000952) EquivalentTo [large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000957) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [pre-B cell receptor complex](http://purl.obolibrary.org/obo/GO_0035369)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [immunoglobulin iota chain](http://purl.obolibrary.org/obo/PR_000001858)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [immunoglobulin lambda-like polypeptide 1](http://purl.obolibrary.org/obo/PR_000001859)) and ([has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [immunoglobulin light chain V-J recombination](http://purl.obolibrary.org/obo/GO_0071708)) + +- [preBCR-positive large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000952) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [immunoglobulin light chain V-J recombination](http://purl.obolibrary.org/obo/GO_0071708) + +#### Added +- [preBCR-positive large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000952) EquivalentTo [large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000957) and ([has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [immunoglobulin light chain V-J recombination](http://purl.obolibrary.org/obo/GO_0071708)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [pre-B cell receptor complex](http://purl.obolibrary.org/obo/GO_0035369)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [immunoglobulin iota chain](http://purl.obolibrary.org/obo/PR_000001858)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [immunoglobulin lambda-like polypeptide 1](http://purl.obolibrary.org/obo/PR_000001859)) + +- [preBCR-positive large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000952) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [immunoglobulin light chain V-J recombination](http://purl.obolibrary.org/obo/GO_0071708) + + +### precursor B cell `http://purl.obolibrary.org/obo/CL_0000817` +#### Removed +- [precursor B cell](http://purl.obolibrary.org/obo/CL_0000817) EquivalentTo [B cell, CD19-positive](http://purl.obolibrary.org/obo/CL_0001201) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [neprilysin](http://purl.obolibrary.org/obo/PR_000001898)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) + +- [precursor B cell](http://purl.obolibrary.org/obo/CL_0000817) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753) + +#### Added +- [precursor B cell](http://purl.obolibrary.org/obo/CL_0000817) EquivalentTo [B cell, CD19-positive](http://purl.obolibrary.org/obo/CL_0001201) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [neprilysin](http://purl.obolibrary.org/obo/PR_000001898)) + +- [precursor B cell](http://purl.obolibrary.org/obo/CL_0000817) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753) + + +### precursor cell `http://purl.obolibrary.org/obo/CL_0011115` +#### Removed +- [precursor cell](http://purl.obolibrary.org/obo/CL_0011115) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### pregnane `http://purl.obolibrary.org/obo/CHEBI_8386` +#### Removed +- [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H][C@]1(CC)CC[C@@]2([H])[C@]3([H])CCC4([H])CCCC[C@]4(C)[C@@]3([H])CC[C@]12C" + +- [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:8386" + +- [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C21H36" + +- [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LIPID_MAPS_instance:LMST02030000" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "LIPID MAPS" + +- [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "JWMFYGXQPXQEEM-WZBAXQLOSA-N" + +- [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) [mass](http://purl.obolibrary.org/obo/chebi/mass) "288.51054" + +- [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pregnane" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "288.28170" + +- [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C21H36/c1-4-15-9-11-18-17-10-8-16-7-5-6-13-20(16,2)19(17)12-14-21(15,18)3/h15-19H,4-14H2,1-3H3/t15-,16?,17-,18-,19-,20-,21+/m0/s1" + +- [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) [label](http://www.w3.org/2000/01/rdf-schema#label) "pregnane" + +- [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pregnane" + +- Class: [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) + +- [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) SubClassOf [steroid fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35508) + + + +### present_in_taxon `http://purl.obolibrary.org/obo/RO_0002175` +#### Removed +- [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "https://orcid.org/0000-0002-6601-2165" + +#### Added +- [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### prickle cell `http://purl.obolibrary.org/obo/CL_0000649` +#### Removed +- [prickle cell](http://purl.obolibrary.org/obo/CL_0000649) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0002186" + + + +### primary alcohol `http://purl.obolibrary.org/obo/CHEBI_15734` +#### Removed +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [label](http://www.w3.org/2000/01/rdf-schema#label) "primary alcohol" + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CH3OR" + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:15734" + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [mass](http://purl.obolibrary.org/obo/chebi/mass) "31.034" + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00226" + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a primary alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:57489" + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:8406" + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "31.01839" + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:26262" + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "*C(O)([H])[H]" + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "1-Alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14887" + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Primary alcohol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "primary alcohols" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13676" + +- Class: [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) + +- [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) SubClassOf [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) + + + +### primary alcohol biosynthetic process `http://purl.obolibrary.org/obo/GO_0034309` +#### Removed +- [primary alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0034309) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0034309" + +- [primary alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0034309) [label](http://www.w3.org/2000/01/rdf-schema#label) "primary alcohol biosynthetic process" + +- [primary alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0034309) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [primary alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0034309) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "primary alcohol formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [primary alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0034309) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [primary alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0034309) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "monohydric alcohol biosynthetic process" + +- [primary alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0034309) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "primary alcohol anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [primary alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0034309) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "primary alcohol biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [primary alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0034309) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "primary alcohol synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- Class: [primary alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0034309) + +- [primary alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0034309) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734)) + +- [primary alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0034309) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) + +- [primary alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0034309) SubClassOf [primary alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0034308) + +- [primary alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0034309) SubClassOf [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) + + + +### primary alcohol catabolic process `http://purl.obolibrary.org/obo/GO_0034310` +#### Removed +- [primary alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0034310) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [primary alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0034310) [label](http://www.w3.org/2000/01/rdf-schema#label) "primary alcohol catabolic process" + +- [primary alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0034310) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0034310" + +- [primary alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0034310) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [primary alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0034310) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "primary alcohol breakdown" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [primary alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0034310) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "primary alcohol degradation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [primary alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0034310) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "monohydric alcohol catabolic process" + +- [primary alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0034310) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "primary alcohol catabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- Class: [primary alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0034310) + +- [primary alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0034310) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734)) + +- [primary alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0034310) SubClassOf [alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0046164) + +- [primary alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0034310) SubClassOf [primary alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0034308) + +- [primary alcohol catabolic process](http://purl.obolibrary.org/obo/GO_0034310) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) + + + +### primary alcohol metabolic process `http://purl.obolibrary.org/obo/GO_0034308` +#### Removed +- [primary alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0034308) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [primary alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0034308) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "primary alcohol metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [primary alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0034308) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [primary alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0034308) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0034308" + +- [primary alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0034308) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "monohydric alcohol metabolic process" + +- [primary alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0034308) [label](http://www.w3.org/2000/01/rdf-schema#label) "primary alcohol metabolic process" + +- Class: [primary alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0034308) + +- [primary alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0034308) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734)) + +- [primary alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0034308) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) + +- [primary alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0034308) SubClassOf [alcohol metabolic process](http://purl.obolibrary.org/obo/GO_0006066) + + + +### primary alpha-hydroxy ketone `http://purl.obolibrary.org/obo/CHEBI_139590` +#### Removed +- [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "*C(C(O)([H])[H])=O" + +- [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C2H3O2R" + +- [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) [mass](http://purl.obolibrary.org/obo/chebi/mass) "59.044" + +- [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) [label](http://www.w3.org/2000/01/rdf-schema#label) "primary alpha-hydroxy ketone" + +- [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:139590" + +- [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "primary alpha-hydroxy ketones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "primary alpha-hydroxyketone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "59.01330" + +- [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An alpha-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a -CH2 (methylene) group." + +- [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "primary alpha-hydroxyketones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "primary alpha-hydroxy-ketones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "primary alpha-hydroxy-ketone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) + +- [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) SubClassOf [primary alcohol](http://purl.obolibrary.org/obo/CHEBI_15734) + +- [primary alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139590) SubClassOf [alpha-hydroxy ketone](http://purl.obolibrary.org/obo/CHEBI_139588) + + + +### primary amide `http://purl.obolibrary.org/obo/CHEBI_33256` +#### Removed +- [primary amide](http://purl.obolibrary.org/obo/CHEBI_33256) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [primary amide](http://purl.obolibrary.org/obo/CHEBI_33256) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "primary amide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [primary amide](http://purl.obolibrary.org/obo/CHEBI_33256) [label](http://www.w3.org/2000/01/rdf-schema#label) "primary amide" + +- [primary amide](http://purl.obolibrary.org/obo/CHEBI_33256) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33256" + +- [primary amide](http://purl.obolibrary.org/obo/CHEBI_33256) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "primary amide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + +- [primary amide](http://purl.obolibrary.org/obo/CHEBI_33256) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "primary amides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [primary amide](http://purl.obolibrary.org/obo/CHEBI_33256) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "primary amides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [primary amide](http://purl.obolibrary.org/obo/CHEBI_33256) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [primary amide](http://purl.obolibrary.org/obo/CHEBI_33256) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- Class: [primary amide](http://purl.obolibrary.org/obo/CHEBI_33256) + +- [primary amide](http://purl.obolibrary.org/obo/CHEBI_33256) SubClassOf [amide](http://purl.obolibrary.org/obo/CHEBI_32988) + + + +### primary amino compound `http://purl.obolibrary.org/obo/CHEBI_50994` +#### Removed +- [primary amino compound](http://purl.obolibrary.org/obo/CHEBI_50994) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "primary amino compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [primary amino compound](http://purl.obolibrary.org/obo/CHEBI_50994) [label](http://www.w3.org/2000/01/rdf-schema#label) "primary amino compound" + +- [primary amino compound](http://purl.obolibrary.org/obo/CHEBI_50994) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [primary amino compound](http://purl.obolibrary.org/obo/CHEBI_50994) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) + +- [primary amino compound](http://purl.obolibrary.org/obo/CHEBI_50994) SubClassOf [organic amino compound](http://purl.obolibrary.org/obo/CHEBI_50047) + + + +### primary amino compound biosynthetic process `http://purl.obolibrary.org/obo/GO_1901162` +#### Removed +- [primary amino compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901162) SubClassOf [organonitrogen compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901566) + +#### Added +- [primary amino compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901162) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### primary amino compound catabolic process `http://purl.obolibrary.org/obo/GO_1901161` +#### Removed +- [primary amino compound catabolic process](http://purl.obolibrary.org/obo/GO_1901161) SubClassOf [organonitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_1901565) + +#### Added +- [primary amino compound catabolic process](http://purl.obolibrary.org/obo/GO_1901161) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### primary ammonium ion `http://purl.obolibrary.org/obo/CHEBI_65296` +#### Removed +- [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) [label](http://www.w3.org/2000/01/rdf-schema#label) "primary ammonium ion" + +- [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a primary amine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+1" + +- [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[NH3+][*]" + +- [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) [formula](http://purl.obolibrary.org/obo/chebi/formula) "H3NR" + +- [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3." + +- [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "17.02655" + +- [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) [mass](http://purl.obolibrary.org/obo/chebi/mass) "17.031" + +- [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "substituted ammonium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:65296" + +- Class: [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) + +- [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) SubClassOf [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) + +- [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) SubClassOf [organic cation](http://purl.obolibrary.org/obo/CHEBI_25697) + +- [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [primary amino compound](http://purl.obolibrary.org/obo/CHEBI_50994) + + + +### primary oocyte `http://purl.obolibrary.org/obo/CL_0000654` +#### Removed +- [primary oocyte](http://purl.obolibrary.org/obo/CL_0000654) EquivalentTo [oocyte](http://purl.obolibrary.org/obo/CL_0000023) and ([has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [meiotic cell cycle](http://purl.obolibrary.org/obo/GO_0051321)) + +- [primary oocyte](http://purl.obolibrary.org/obo/CL_0000654) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [meiotic cell cycle](http://purl.obolibrary.org/obo/GO_0051321) + +#### Added +- [primary oocyte](http://purl.obolibrary.org/obo/CL_0000654) EquivalentTo [oocyte](http://purl.obolibrary.org/obo/CL_0000023) and ([has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [meiotic cell cycle](http://purl.obolibrary.org/obo/GO_0051321)) + +- [primary oocyte](http://purl.obolibrary.org/obo/CL_0000654) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [meiotic cell cycle](http://purl.obolibrary.org/obo/GO_0051321) + + +### primitive erythroid progenitor `http://purl.obolibrary.org/obo/CL_0002361` + +#### Added +- [primitive erythroid progenitor](http://purl.obolibrary.org/obo/CL_0002361) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + + +### primitive red blood cell `http://purl.obolibrary.org/obo/CL_0002355` + +#### Added +- [primitive red blood cell](http://purl.obolibrary.org/obo/CL_0002355) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + + +### pro-NK cell `http://purl.obolibrary.org/obo/CL_0000825` +#### Removed +- [pro-NK cell](http://purl.obolibrary.org/obo/CL_0000825) EquivalentTo [lymphoid lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0000838) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit beta](http://purl.obolibrary.org/obo/PR_000001381)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [neprilysin](http://purl.obolibrary.org/obo/PR_000001898)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) + +- [pro-NK cell](http://purl.obolibrary.org/obo/CL_0000825) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874) + +- [pro-NK cell](http://purl.obolibrary.org/obo/CL_0000825) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065) + +#### Added +- [pro-NK cell](http://purl.obolibrary.org/obo/CL_0000825) EquivalentTo [lymphoid lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0000838) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit beta](http://purl.obolibrary.org/obo/PR_000001381)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [neprilysin](http://purl.obolibrary.org/obo/PR_000001898)) + +- [pro-NK cell](http://purl.obolibrary.org/obo/CL_0000825) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [mast/stem cell growth factor receptor](http://purl.obolibrary.org/obo/PR_000002065) + +- [pro-NK cell](http://purl.obolibrary.org/obo/CL_0000825) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874) + + +### produced by `http://purl.obolibrary.org/obo/RO_0003001` +#### Removed +- [produced by](http://purl.obolibrary.org/obo/RO_0003001) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Melissa Haendel" + +#### Added +- [produced by](http://purl.obolibrary.org/obo/RO_0003001) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0001-9114-8737](https://orcid.org/0000-0001-9114-8737) + + +### produces `http://purl.obolibrary.org/obo/RO_0003000` +#### Removed +- [produces](http://purl.obolibrary.org/obo/RO_0003000) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Melissa Haendel" + +#### Added +- [produces](http://purl.obolibrary.org/obo/RO_0003000) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0001-9114-8737](https://orcid.org/0000-0001-9114-8737) + + +### proerythroblast `http://purl.obolibrary.org/obo/CL_0000547` +#### Removed +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) EquivalentTo [erythroid lineage cell](http://purl.obolibrary.org/obo/CL_0000764) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [basophilic cytoplasm](http://purl.obolibrary.org/obo/CL_0017503)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nucleolus](http://purl.obolibrary.org/obo/GO_0005730)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [nucleated](http://purl.obolibrary.org/obo/PATO_0002505)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +#### Added +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) EquivalentTo [erythroid lineage cell](http://purl.obolibrary.org/obo/CL_0000764) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [basophilic cytoplasm](http://purl.obolibrary.org/obo/CL_0017503)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nucleolus](http://purl.obolibrary.org/obo/GO_0005730)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [nucleated](http://purl.obolibrary.org/obo/PATO_0002505)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + + +### progesterone `http://purl.obolibrary.org/obo/CHEBI_17026` +#### Removed +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "progesterone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:8453" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C21H30O2" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Progesterone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:45786" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [label](http://www.w3.org/2000/01/rdf-schema#label) "progesterone" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "17alpha-progesterone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Progesteron" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Progesterone" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "luteohormone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:1915950" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D00066" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:STR" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "RJKFOVLPORLFTN-LEKSSAKUSA-N" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "PROGESTERONE" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-Pregnene-3,20-dione" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:PROGESTERONE" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(S)-Progesterone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(S)-4-Pregnene-3,20-dione" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10438974" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus luteum hormone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:1915950" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:2279" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9506942" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Gelbkoerperhormon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:439" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Agolutin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Delta(4)-pregnene-3,20-dione" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:57-83-0" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14896" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:26269" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:17026" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB00396" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pregn-4-ene-3,20-dione" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(S)-Pregn-4-en-3,20-dione" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [mass](http://purl.obolibrary.org/obo/chebi/mass) "314.46170" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:18798" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00410" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0001830" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:57-83-0" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:57-83-0" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Crinone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:708590" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "314.22458" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species." + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])C(C)=O" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Akrolutin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [progesterone receptor agonist](http://purl.obolibrary.org/obo/CHEBI_70709) + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) SubClassOf [has_parent_hydride](http://purl.obolibrary.org/obo/chebi#has_parent_hydride) some [pregnane](http://purl.obolibrary.org/obo/CHEBI_8386) + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [progestin](http://purl.obolibrary.org/obo/CHEBI_59826) + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) SubClassOf [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) SubClassOf [C21-steroid hormone](http://purl.obolibrary.org/obo/CHEBI_64600) + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) SubClassOf [20-oxo steroid](http://purl.obolibrary.org/obo/CHEBI_36885) + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [progesterone](http://purl.obolibrary.org/obo/CHEBI_17026) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [contraceptive drug](http://purl.obolibrary.org/obo/CHEBI_49323) + + + +### progesterone biosynthetic process `http://purl.obolibrary.org/obo/GO_0006701` +#### Removed +- [progesterone biosynthetic process](http://purl.obolibrary.org/obo/GO_0006701) SubClassOf [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) + +- [progesterone biosynthetic process](http://purl.obolibrary.org/obo/GO_0006701) SubClassOf [C21-steroid hormone biosynthetic process](http://purl.obolibrary.org/obo/GO_0006700) + +- [progesterone biosynthetic process](http://purl.obolibrary.org/obo/GO_0006701) SubClassOf [ketone biosynthetic process](http://purl.obolibrary.org/obo/GO_0042181) + +#### Added +- [progesterone biosynthetic process](http://purl.obolibrary.org/obo/GO_0006701) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### progesterone catabolic process `http://purl.obolibrary.org/obo/GO_0006709` +#### Removed +- [progesterone catabolic process](http://purl.obolibrary.org/obo/GO_0006709) SubClassOf [olefinic compound catabolic process](http://purl.obolibrary.org/obo/GO_0120256) + +- [progesterone catabolic process](http://purl.obolibrary.org/obo/GO_0006709) SubClassOf [C21-steroid hormone catabolic process](http://purl.obolibrary.org/obo/GO_0008208) + +- [progesterone catabolic process](http://purl.obolibrary.org/obo/GO_0006709) SubClassOf [ketone catabolic process](http://purl.obolibrary.org/obo/GO_0042182) + +#### Added +- [progesterone catabolic process](http://purl.obolibrary.org/obo/GO_0006709) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### progesterone metabolic process `http://purl.obolibrary.org/obo/GO_0042448` +#### Removed +- [progesterone metabolic process](http://purl.obolibrary.org/obo/GO_0042448) SubClassOf [olefinic compound metabolic process](http://purl.obolibrary.org/obo/GO_0120254) + +- [progesterone metabolic process](http://purl.obolibrary.org/obo/GO_0042448) SubClassOf [C21-steroid hormone metabolic process](http://purl.obolibrary.org/obo/GO_0008207) + +- [progesterone metabolic process](http://purl.obolibrary.org/obo/GO_0042448) SubClassOf [cellular ketone metabolic process](http://purl.obolibrary.org/obo/GO_0042180) + +#### Added +- [progesterone metabolic process](http://purl.obolibrary.org/obo/GO_0042448) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### progesterone receptor agonist `http://purl.obolibrary.org/obo/CHEBI_70709` +#### Removed +- [progesterone receptor agonist](http://purl.obolibrary.org/obo/CHEBI_70709) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "progesterone receptor agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [progesterone receptor agonist](http://purl.obolibrary.org/obo/CHEBI_70709) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "PR agonist" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [progesterone receptor agonist](http://purl.obolibrary.org/obo/CHEBI_70709) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A hormone agonist that binds to and activates progesterone receptors." + +- [progesterone receptor agonist](http://purl.obolibrary.org/obo/CHEBI_70709) [label](http://www.w3.org/2000/01/rdf-schema#label) "progesterone receptor agonist" + +- [progesterone receptor agonist](http://purl.obolibrary.org/obo/CHEBI_70709) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "PR agonists" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [progesterone receptor agonist](http://purl.obolibrary.org/obo/CHEBI_70709) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [progesterone receptor agonist](http://purl.obolibrary.org/obo/CHEBI_70709) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:70709" + +- [progesterone receptor agonist](http://purl.obolibrary.org/obo/CHEBI_70709) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [progesterone receptor agonist](http://purl.obolibrary.org/obo/CHEBI_70709) + +- [progesterone receptor agonist](http://purl.obolibrary.org/obo/CHEBI_70709) SubClassOf [hormone agonist](http://purl.obolibrary.org/obo/CHEBI_51060) + + + +### progestin `http://purl.obolibrary.org/obo/CHEBI_59826` +#### Removed +- [progestin](http://purl.obolibrary.org/obo/CHEBI_59826) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [progestin](http://purl.obolibrary.org/obo/CHEBI_59826) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [progestin](http://purl.obolibrary.org/obo/CHEBI_59826) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Progestin" + +- [progestin](http://purl.obolibrary.org/obo/CHEBI_59826) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:59826" + +- [progestin](http://purl.obolibrary.org/obo/CHEBI_59826) [label](http://www.w3.org/2000/01/rdf-schema#label) "progestin" + +- [progestin](http://purl.obolibrary.org/obo/CHEBI_59826) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A synthetic progestogen." + +- [progestin](http://purl.obolibrary.org/obo/CHEBI_59826) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "progestins" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [progestin](http://purl.obolibrary.org/obo/CHEBI_59826) + +- [progestin](http://purl.obolibrary.org/obo/CHEBI_59826) SubClassOf [progestogen](http://purl.obolibrary.org/obo/CHEBI_50745) + + + +### progestogen `http://purl.obolibrary.org/obo/CHEBI_50745` +#### Removed +- [progestogen](http://purl.obolibrary.org/obo/CHEBI_50745) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gestagens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [progestogen](http://purl.obolibrary.org/obo/CHEBI_50745) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "progestogens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [progestogen](http://purl.obolibrary.org/obo/CHEBI_50745) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [progestogen](http://purl.obolibrary.org/obo/CHEBI_50745) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gestagen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [progestogen](http://purl.obolibrary.org/obo/CHEBI_50745) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50745" + +- [progestogen](http://purl.obolibrary.org/obo/CHEBI_50745) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "progestagens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [progestogen](http://purl.obolibrary.org/obo/CHEBI_50745) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "progestagen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [progestogen](http://purl.obolibrary.org/obo/CHEBI_50745) [label](http://www.w3.org/2000/01/rdf-schema#label) "progestogen" + +- [progestogen](http://purl.obolibrary.org/obo/CHEBI_50745) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [progestogen](http://purl.obolibrary.org/obo/CHEBI_50745) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A compound that interacts with progesterone receptors in target tissues to bring about effects similar to those of progesterone." + +- Class: [progestogen](http://purl.obolibrary.org/obo/CHEBI_50745) + +- [progestogen](http://purl.obolibrary.org/obo/CHEBI_50745) SubClassOf [sex hormone](http://purl.obolibrary.org/obo/CHEBI_50112) + + + +### programmed cell death `http://purl.obolibrary.org/obo/GO_0012501` + +#### Added +- [programmed cell death](http://purl.obolibrary.org/obo/GO_0012501) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_plant](http://purl.obolibrary.org/obo/go#goslim_plant) + +- [programmed cell death](http://purl.obolibrary.org/obo/GO_0012501) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_chembl](http://purl.obolibrary.org/obo/go#goslim_chembl) + +- [programmed cell death](http://purl.obolibrary.org/obo/GO_0012501) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_agr](http://purl.obolibrary.org/obo/go#goslim_agr) + +- [programmed cell death](http://purl.obolibrary.org/obo/GO_0012501) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_drosophila](http://purl.obolibrary.org/obo/go#goslim_drosophila) + +- [programmed cell death](http://purl.obolibrary.org/obo/GO_0012501) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_mouse](http://purl.obolibrary.org/obo/go#goslim_mouse) + +- [programmed cell death](http://purl.obolibrary.org/obo/GO_0012501) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24835"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### prokaryotic metabolite `http://purl.obolibrary.org/obo/CHEBI_75787` +#### Removed +- [prokaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75787) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [prokaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75787) [label](http://www.w3.org/2000/01/rdf-schema#label) "prokaryotic metabolite" + +- [prokaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75787) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea." + +- [prokaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75787) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:75787" + +- [prokaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75787) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "prokaryotic metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [prokaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75787) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [prokaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75787) + +- [prokaryotic metabolite](http://purl.obolibrary.org/obo/CHEBI_75787) SubClassOf [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) + + + +### promyelocyte `http://purl.obolibrary.org/obo/CL_0000836` +#### Removed +- [promyelocyte](http://purl.obolibrary.org/obo/CL_0000836) EquivalentTo [myeloid lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0000839) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [basophilic cytoplasm](http://purl.obolibrary.org/obo/CL_0017503)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nucleolus](http://purl.obolibrary.org/obo/GO_0005730)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-(1,3)-fucosyltransferase 4](http://purl.obolibrary.org/obo/PR_000001456)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD33 molecule](http://purl.obolibrary.org/obo/PR_000001892)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) + +- [promyelocyte](http://purl.obolibrary.org/obo/CL_0000836) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [promyelocyte](http://purl.obolibrary.org/obo/CL_0000836) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483) + +- [promyelocyte](http://purl.obolibrary.org/obo/CL_0000836) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932) + +#### Added +- [promyelocyte](http://purl.obolibrary.org/obo/CL_0000836) EquivalentTo [myeloid lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0000839) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [basophilic cytoplasm](http://purl.obolibrary.org/obo/CL_0017503)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nucleolus](http://purl.obolibrary.org/obo/GO_0005730)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-(1,3)-fucosyltransferase 4](http://purl.obolibrary.org/obo/PR_000001456)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD33 molecule](http://purl.obolibrary.org/obo/PR_000001892)) + +- [promyelocyte](http://purl.obolibrary.org/obo/CL_0000836) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [promyelocyte](http://purl.obolibrary.org/obo/CL_0000836) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932) + +- [promyelocyte](http://purl.obolibrary.org/obo/CL_0000836) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483) + + +### protective agent `http://purl.obolibrary.org/obo/CHEBI_50267` +#### Removed +- [protective agent](http://purl.obolibrary.org/obo/CHEBI_50267) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [protective agent](http://purl.obolibrary.org/obo/CHEBI_50267) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chemoprotective agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [protective agent](http://purl.obolibrary.org/obo/CHEBI_50267) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "protective agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [protective agent](http://purl.obolibrary.org/obo/CHEBI_50267) [label](http://www.w3.org/2000/01/rdf-schema#label) "protective agent" + +- [protective agent](http://purl.obolibrary.org/obo/CHEBI_50267) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chemoprotectants" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [protective agent](http://purl.obolibrary.org/obo/CHEBI_50267) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [protective agent](http://purl.obolibrary.org/obo/CHEBI_50267) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chemoprotectant" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [protective agent](http://purl.obolibrary.org/obo/CHEBI_50267) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50267" + +- [protective agent](http://purl.obolibrary.org/obo/CHEBI_50267) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chemoprotective agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [protective agent](http://purl.obolibrary.org/obo/CHEBI_50267) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent." + +- Class: [protective agent](http://purl.obolibrary.org/obo/CHEBI_50267) + +- [protective agent](http://purl.obolibrary.org/obo/CHEBI_50267) SubClassOf [drug](http://purl.obolibrary.org/obo/CHEBI_23888) + + + +### protein `http://purl.obolibrary.org/obo/CHEBI_36080` +#### Removed +- [protein](http://purl.obolibrary.org/obo/CHEBI_36080) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:14911" + +- [protein](http://purl.obolibrary.org/obo/CHEBI_36080) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome." + +- [protein](http://purl.obolibrary.org/obo/CHEBI_36080) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36080" + +- [protein](http://purl.obolibrary.org/obo/CHEBI_36080) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13677" + +- [protein](http://purl.obolibrary.org/obo/CHEBI_36080) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [protein](http://purl.obolibrary.org/obo/CHEBI_36080) [label](http://www.w3.org/2000/01/rdf-schema#label) "protein" + +- [protein](http://purl.obolibrary.org/obo/CHEBI_36080) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [protein](http://purl.obolibrary.org/obo/CHEBI_36080) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "proteins" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + + + +### protein catabolic process `http://purl.obolibrary.org/obo/GO_0030163` +#### Removed +- [protein catabolic process](http://purl.obolibrary.org/obo/GO_0030163) SubClassOf [macromolecule catabolic process](http://purl.obolibrary.org/obo/GO_0009057) + +- [protein catabolic process](http://purl.obolibrary.org/obo/GO_0030163) SubClassOf [organonitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_1901565) + +#### Added +- [protein catabolic process](http://purl.obolibrary.org/obo/GO_0030163) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### protein metabolic process `http://purl.obolibrary.org/obo/GO_0019538` +#### Removed +- [protein metabolic process](http://purl.obolibrary.org/obo/GO_0019538) SubClassOf [organonitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_1901564) + +- [protein metabolic process](http://purl.obolibrary.org/obo/GO_0019538) SubClassOf [macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0043170) + + + +### protein modification process `http://purl.obolibrary.org/obo/GO_0036211` +#### Removed +- [protein modification process](http://purl.obolibrary.org/obo/GO_0036211) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_generic](http://purl.obolibrary.org/obo/go#goslim_generic) + + + +### protein polypeptide chain `http://purl.obolibrary.org/obo/CHEBI_16541` +#### Removed +- [protein polypeptide chain](http://purl.obolibrary.org/obo/CHEBI_16541) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polypeptide chain" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [protein polypeptide chain](http://purl.obolibrary.org/obo/CHEBI_16541) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Protein" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [protein polypeptide chain](http://purl.obolibrary.org/obo/CHEBI_16541) [label](http://www.w3.org/2000/01/rdf-schema#label) "protein polypeptide chain" + +- [protein polypeptide chain](http://purl.obolibrary.org/obo/CHEBI_16541) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a protein" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [protein polypeptide chain](http://purl.obolibrary.org/obo/CHEBI_16541) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [protein polypeptide chain](http://purl.obolibrary.org/obo/CHEBI_16541) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:16541" + +- [protein polypeptide chain](http://purl.obolibrary.org/obo/CHEBI_16541) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [protein polypeptide chain](http://purl.obolibrary.org/obo/CHEBI_16541) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "protein polypeptide chains" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [protein polypeptide chain](http://purl.obolibrary.org/obo/CHEBI_16541) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A naturally occurring polypeptide synthesized at the ribosome." + +- [protein polypeptide chain](http://purl.obolibrary.org/obo/CHEBI_16541) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:8526" + +- [protein polypeptide chain](http://purl.obolibrary.org/obo/CHEBI_16541) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00017" + +- [protein polypeptide chain](http://purl.obolibrary.org/obo/CHEBI_16541) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [proteinogenic amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33700) + +- [protein polypeptide chain](http://purl.obolibrary.org/obo/CHEBI_16541) SubClassOf [polypeptide](http://purl.obolibrary.org/obo/CHEBI_15841) + + + +### protein serine/threonine kinase inhibitor activity `http://purl.obolibrary.org/obo/GO_0030291` +#### Removed +- [protein serine/threonine kinase inhibitor activity](http://purl.obolibrary.org/obo/GO_0030291) EquivalentTo [molecular_function](http://purl.obolibrary.org/obo/GO_0003674) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [protein serine/threonine kinase activity](http://purl.obolibrary.org/obo/GO_0004674)) + +- [protein serine/threonine kinase inhibitor activity](http://purl.obolibrary.org/obo/GO_0030291) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [protein serine/threonine kinase activity](http://purl.obolibrary.org/obo/GO_0004674) + +- [protein serine/threonine kinase inhibitor activity](http://purl.obolibrary.org/obo/GO_0030291) SubClassOf [molecular_function](http://purl.obolibrary.org/obo/GO_0003674) + +#### Added +- [protein serine/threonine kinase inhibitor activity](http://purl.obolibrary.org/obo/GO_0030291) EquivalentTo [molecular function regulator activity](http://purl.obolibrary.org/obo/GO_0098772) and ([directly negatively regulates](http://purl.obolibrary.org/obo/RO_0002630) some [protein serine/threonine kinase activity](http://purl.obolibrary.org/obo/GO_0004674)) + +- [protein serine/threonine kinase inhibitor activity](http://purl.obolibrary.org/obo/GO_0030291) SubClassOf [directly negatively regulates](http://purl.obolibrary.org/obo/RO_0002630) some [protein serine/threonine kinase activity](http://purl.obolibrary.org/obo/GO_0004674) + +- [protein serine/threonine kinase inhibitor activity](http://purl.obolibrary.org/obo/GO_0030291) SubClassOf [protein kinase inhibitor activity](http://purl.obolibrary.org/obo/GO_0004860) + + +### protein transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0008320` +#### Removed +- [protein transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008320) SubClassOf [macromolecule transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022884) + +#### Added +- [protein transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0008320) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + +### protein transport `http://purl.obolibrary.org/obo/GO_0015031` +#### Removed +- [protein transport](http://purl.obolibrary.org/obo/GO_0015031) SubClassOf [nitrogen compound transport](http://purl.obolibrary.org/obo/GO_0071705) + + + +### protein tyrosine kinase activity `http://purl.obolibrary.org/obo/GO_0004713` +#### Removed +- [protein tyrosine kinase activity](http://purl.obolibrary.org/obo/GO_0004713) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [peptidyl-tyrosine phosphorylation](http://purl.obolibrary.org/obo/GO_0018108) + + + +### proteinogenic amino acid `http://purl.obolibrary.org/obo/CHEBI_83813` +#### Removed +- [proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83813) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canonical amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83813) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "proteinogenic amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83813) [label](http://www.w3.org/2000/01/rdf-schema#label) "proteinogenic amino acid" + +- [proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83813) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83813) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Proteinogenic_amino_acid" + +- [proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83813) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:83813" + +- [proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83813) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any of the 23 alpha-amino acids that are precursors to proteins, and are incorporated into proteins during translation. The group includes the 20 amino acids encoded by the nuclear genes of eukaryotes together with selenocysteine, pyrrolysine, and N-formylmethionine. Apart from glycine, which is non-chiral, all have L configuration." + +- [proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83813) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canonical amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83813) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83813) + +- [proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83813) SubClassOf [organonitrogen compound](http://purl.obolibrary.org/obo/CHEBI_35352) + +- [proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83813) SubClassOf [carboxylic acid](http://purl.obolibrary.org/obo/CHEBI_33575) + + + +### proteinogenic amino-acid residue `http://purl.obolibrary.org/obo/CHEBI_33700` +#### Removed +- [proteinogenic amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33700) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "standard amino acid residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [proteinogenic amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33700) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "proteinogenic amino-acid residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [proteinogenic amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33700) [label](http://www.w3.org/2000/01/rdf-schema#label) "proteinogenic amino-acid residue" + +- [proteinogenic amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33700) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "common amino acid residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [proteinogenic amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33700) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [proteinogenic amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33700) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [proteinogenic amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33700) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canonical amino-acid residue" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [proteinogenic amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33700) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canonical amino-acid residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [proteinogenic amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33700) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "standard amino-acid residues" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [proteinogenic amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33700) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33700" + +- Class: [proteinogenic amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33700) + +- [proteinogenic amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33700) SubClassOf [alpha-amino-acid residue](http://purl.obolibrary.org/obo/CHEBI_33710) + + + +### proteinogenic amino-acid side-chain group `http://purl.obolibrary.org/obo/CHEBI_50325` +#### Removed +- [proteinogenic amino-acid side-chain group](http://purl.obolibrary.org/obo/CHEBI_50325) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "proteinogenic amino-acid side-chain groups" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [proteinogenic amino-acid side-chain group](http://purl.obolibrary.org/obo/CHEBI_50325) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50325" + +- [proteinogenic amino-acid side-chain group](http://purl.obolibrary.org/obo/CHEBI_50325) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A univalent organyl group obtained by cleaving the bond from C-2 to the side chain of a proteinogenic amino-acid." + +- [proteinogenic amino-acid side-chain group](http://purl.obolibrary.org/obo/CHEBI_50325) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [proteinogenic amino-acid side-chain group](http://purl.obolibrary.org/obo/CHEBI_50325) [label](http://www.w3.org/2000/01/rdf-schema#label) "proteinogenic amino-acid side-chain group" + +- [proteinogenic amino-acid side-chain group](http://purl.obolibrary.org/obo/CHEBI_50325) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "proteinogenic amino-acid side-chains" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [proteinogenic amino-acid side-chain group](http://purl.obolibrary.org/obo/CHEBI_50325) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canonical amino-acid side-chains" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [proteinogenic amino-acid side-chain group](http://purl.obolibrary.org/obo/CHEBI_50325) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "proteinogenic amino-acid side-chain" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [proteinogenic amino-acid side-chain group](http://purl.obolibrary.org/obo/CHEBI_50325) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canonical amino-acid side-chain" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [proteinogenic amino-acid side-chain group](http://purl.obolibrary.org/obo/CHEBI_50325) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [proteinogenic amino-acid side-chain group](http://purl.obolibrary.org/obo/CHEBI_50325) + +- [proteinogenic amino-acid side-chain group](http://purl.obolibrary.org/obo/CHEBI_50325) SubClassOf [organyl group](http://purl.obolibrary.org/obo/CHEBI_33249) + + + +### proteoglycan `http://purl.obolibrary.org/obo/CHEBI_37396` +#### Removed +- [proteoglycan](http://purl.obolibrary.org/obo/CHEBI_37396) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Proteoglycan" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [proteoglycan](http://purl.obolibrary.org/obo/CHEBI_37396) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "proteoglycans" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [proteoglycan](http://purl.obolibrary.org/obo/CHEBI_37396) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [proteoglycan](http://purl.obolibrary.org/obo/CHEBI_37396) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [proteoglycan](http://purl.obolibrary.org/obo/CHEBI_37396) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:8582" + +- [proteoglycan](http://purl.obolibrary.org/obo/CHEBI_37396) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:26351" + +- [proteoglycan](http://purl.obolibrary.org/obo/CHEBI_37396) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:37396" + +- [proteoglycan](http://purl.obolibrary.org/obo/CHEBI_37396) [label](http://www.w3.org/2000/01/rdf-schema#label) "proteoglycan" + +- [proteoglycan](http://purl.obolibrary.org/obo/CHEBI_37396) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00866" + +- [proteoglycan](http://purl.obolibrary.org/obo/CHEBI_37396) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A glycoprotein in which the carbohydrate units are polysaccharides that contain amino sugars. The protein is glycosylated by one or more (up to about 100) glycosaminoglycans." + +- [proteoglycan](http://purl.obolibrary.org/obo/CHEBI_37396) SubClassOf [glycoprotein](http://purl.obolibrary.org/obo/CHEBI_17089) + +- [proteoglycan](http://purl.obolibrary.org/obo/CHEBI_37396) SubClassOf [polysaccharide derivative](http://purl.obolibrary.org/obo/CHEBI_65212) + + + +### proteoglycan binding `http://purl.obolibrary.org/obo/GO_0043394` +#### Removed +- [proteoglycan binding](http://purl.obolibrary.org/obo/GO_0043394) SubClassOf [carbohydrate derivative binding](http://purl.obolibrary.org/obo/GO_0097367) + +- [proteoglycan binding](http://purl.obolibrary.org/obo/GO_0043394) SubClassOf [protein binding](http://purl.obolibrary.org/obo/GO_0005515) + +#### Added +- [proteoglycan binding](http://purl.obolibrary.org/obo/GO_0043394) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### proteoglycan biosynthetic process `http://purl.obolibrary.org/obo/GO_0030166` +#### Removed +- [proteoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0030166) SubClassOf [glycoprotein biosynthetic process](http://purl.obolibrary.org/obo/GO_0009101) + +#### Added +- [proteoglycan biosynthetic process](http://purl.obolibrary.org/obo/GO_0030166) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### proteoglycan catabolic process `http://purl.obolibrary.org/obo/GO_0030167` +#### Removed +- [proteoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0030167) SubClassOf [glycoprotein catabolic process](http://purl.obolibrary.org/obo/GO_0006516) + +#### Added +- [proteoglycan catabolic process](http://purl.obolibrary.org/obo/GO_0030167) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### proteoglycan metabolic process `http://purl.obolibrary.org/obo/GO_0006029` +#### Removed +- [proteoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0006029) SubClassOf [glycoprotein metabolic process](http://purl.obolibrary.org/obo/GO_0009100) + +#### Added +- [proteoglycan metabolic process](http://purl.obolibrary.org/obo/GO_0006029) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### protic solvent `http://purl.obolibrary.org/obo/CHEBI_48356` +#### Removed +- [protic solvent](http://purl.obolibrary.org/obo/CHEBI_48356) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "protogenic solvent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [protic solvent](http://purl.obolibrary.org/obo/CHEBI_48356) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [protic solvent](http://purl.obolibrary.org/obo/CHEBI_48356) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [protic solvent](http://purl.obolibrary.org/obo/CHEBI_48356) [label](http://www.w3.org/2000/01/rdf-schema#label) "protic solvent" + +- [protic solvent](http://purl.obolibrary.org/obo/CHEBI_48356) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:48356" + +- [protic solvent](http://purl.obolibrary.org/obo/CHEBI_48356) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A polar solvent that is capable of acting as a hydron (proton) donor." + +- Class: [protic solvent](http://purl.obolibrary.org/obo/CHEBI_48356) + +- [protic solvent](http://purl.obolibrary.org/obo/CHEBI_48356) SubClassOf [Bronsted acid](http://purl.obolibrary.org/obo/CHEBI_39141) + +- [protic solvent](http://purl.obolibrary.org/obo/CHEBI_48356) SubClassOf [polar solvent](http://purl.obolibrary.org/obo/CHEBI_48354) + + + +### protophilic solvent `http://purl.obolibrary.org/obo/CHEBI_48359` +#### Removed +- [protophilic solvent](http://purl.obolibrary.org/obo/CHEBI_48359) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrogen bond acceptor solvent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [protophilic solvent](http://purl.obolibrary.org/obo/CHEBI_48359) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HBA solvent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [protophilic solvent](http://purl.obolibrary.org/obo/CHEBI_48359) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:48359" + +- [protophilic solvent](http://purl.obolibrary.org/obo/CHEBI_48359) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [protophilic solvent](http://purl.obolibrary.org/obo/CHEBI_48359) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "protophilic solvent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [protophilic solvent](http://purl.obolibrary.org/obo/CHEBI_48359) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Solvent that is capable of acting as a hydron (proton) acceptor." + +- [protophilic solvent](http://purl.obolibrary.org/obo/CHEBI_48359) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [protophilic solvent](http://purl.obolibrary.org/obo/CHEBI_48359) [label](http://www.w3.org/2000/01/rdf-schema#label) "protophilic solvent" + +- Class: [protophilic solvent](http://purl.obolibrary.org/obo/CHEBI_48359) + +- [protophilic solvent](http://purl.obolibrary.org/obo/CHEBI_48359) SubClassOf [polar solvent](http://purl.obolibrary.org/obo/CHEBI_48354) + +- [protophilic solvent](http://purl.obolibrary.org/obo/CHEBI_48359) SubClassOf [Bronsted base](http://purl.obolibrary.org/obo/CHEBI_39142) + + + +### pulmonary surfactant `http://purl.obolibrary.org/obo/UBERON_0008826` +#### Removed +- [pulmonary surfactant](http://purl.obolibrary.org/obo/UBERON_0008826) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + + + +### quaternary ammonium ion `http://purl.obolibrary.org/obo/CHEBI_35267` +#### Removed +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [mass](http://purl.obolibrary.org/obo/chebi/mass) "14.00670" + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "quaternary ammonium ions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C06703" + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [formula](http://purl.obolibrary.org/obo/chebi/formula) "NR4" + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[*][N+]([*])([*])[*]" + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+1" + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35267" + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually hydrocarbyl) groups." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [label](http://www.w3.org/2000/01/rdf-schema#label) "quaternary ammonium ion" + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "quaternary ammonium ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "quaternary ammonium ions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:8693" + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "14.00307" + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "quaternary ammonium ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:26470" + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NR4" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [FORMULA](http://purl.obolibrary.org/obo/fbbt#FORMULA) + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Quaternary amine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a quaternary ammonium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[*][N+]([*])([*])[*]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [SMILES](http://purl.obolibrary.org/obo/fbbt#SMILES) + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Quaternary amine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- Class: [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) SubClassOf [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) + +- [quaternary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_35267) SubClassOf [organic cation](http://purl.obolibrary.org/obo/CHEBI_25697) + + + +### radical `http://purl.obolibrary.org/obo/CHEBI_26519` +#### Removed +- [radical](http://purl.obolibrary.org/obo/CHEBI_26519) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "radical" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [radical](http://purl.obolibrary.org/obo/CHEBI_26519) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "free radical" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [radical](http://purl.obolibrary.org/obo/CHEBI_26519) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26519" + +- [radical](http://purl.obolibrary.org/obo/CHEBI_26519) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [radical](http://purl.obolibrary.org/obo/CHEBI_26519) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Radikal" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [radical](http://purl.obolibrary.org/obo/CHEBI_26519) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "radicals" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [radical](http://purl.obolibrary.org/obo/CHEBI_26519) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "radicales libres" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [radical](http://purl.obolibrary.org/obo/CHEBI_26519) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecular entity possessing an unpaired electron." + +- [radical](http://purl.obolibrary.org/obo/CHEBI_26519) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Radikale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [radical](http://purl.obolibrary.org/obo/CHEBI_26519) [label](http://www.w3.org/2000/01/rdf-schema#label) "radical" + +- [radical](http://purl.obolibrary.org/obo/CHEBI_26519) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [radical](http://purl.obolibrary.org/obo/CHEBI_26519) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "radical libre" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [radical](http://purl.obolibrary.org/obo/CHEBI_26519) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "freies Radikal" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [radical](http://purl.obolibrary.org/obo/CHEBI_26519) + +- [radical](http://purl.obolibrary.org/obo/CHEBI_26519) SubClassOf [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) + + + +### radical anion `http://purl.obolibrary.org/obo/CHEBI_36873` +#### Removed +- [radical anion](http://purl.obolibrary.org/obo/CHEBI_36873) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36873" + +- [radical anion](http://purl.obolibrary.org/obo/CHEBI_36873) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anion radical" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [radical anion](http://purl.obolibrary.org/obo/CHEBI_36873) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [radical anion](http://purl.obolibrary.org/obo/CHEBI_36873) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "radical anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [radical anion](http://purl.obolibrary.org/obo/CHEBI_36873) [label](http://www.w3.org/2000/01/rdf-schema#label) "radical anion" + +- [radical anion](http://purl.obolibrary.org/obo/CHEBI_36873) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [radical anion](http://purl.obolibrary.org/obo/CHEBI_36873) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "radical anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [radical anion](http://purl.obolibrary.org/obo/CHEBI_36873) + +- [radical anion](http://purl.obolibrary.org/obo/CHEBI_36873) SubClassOf [radical ion](http://purl.obolibrary.org/obo/CHEBI_36875) + +- [radical anion](http://purl.obolibrary.org/obo/CHEBI_36873) SubClassOf [anion](http://purl.obolibrary.org/obo/CHEBI_22563) + + + +### radical ion `http://purl.obolibrary.org/obo/CHEBI_36875` +#### Removed +- [radical ion](http://purl.obolibrary.org/obo/CHEBI_36875) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "radical ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [radical ion](http://purl.obolibrary.org/obo/CHEBI_36875) [label](http://www.w3.org/2000/01/rdf-schema#label) "radical ion" + +- [radical ion](http://purl.obolibrary.org/obo/CHEBI_36875) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36875" + +- [radical ion](http://purl.obolibrary.org/obo/CHEBI_36875) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "radical ions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [radical ion](http://purl.obolibrary.org/obo/CHEBI_36875) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [radical ion](http://purl.obolibrary.org/obo/CHEBI_36875) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ion radical" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [radical ion](http://purl.obolibrary.org/obo/CHEBI_36875) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A radical that carries an electric charge." + +- [radical ion](http://purl.obolibrary.org/obo/CHEBI_36875) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [radical ion](http://purl.obolibrary.org/obo/CHEBI_36875) + +- [radical ion](http://purl.obolibrary.org/obo/CHEBI_36875) SubClassOf [ion](http://purl.obolibrary.org/obo/CHEBI_24870) + +- [radical ion](http://purl.obolibrary.org/obo/CHEBI_36875) SubClassOf [radical](http://purl.obolibrary.org/obo/CHEBI_26519) + + + +### radical scavenger `http://purl.obolibrary.org/obo/CHEBI_48578` +#### Removed +- [radical scavenger](http://purl.obolibrary.org/obo/CHEBI_48578) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "free radical scavengers" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [radical scavenger](http://purl.obolibrary.org/obo/CHEBI_48578) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:48578" + +- [radical scavenger](http://purl.obolibrary.org/obo/CHEBI_48578) [label](http://www.w3.org/2000/01/rdf-schema#label) "radical scavenger" + +- [radical scavenger](http://purl.obolibrary.org/obo/CHEBI_48578) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [radical scavenger](http://purl.obolibrary.org/obo/CHEBI_48578) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "free-radical scavenger" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [radical scavenger](http://purl.obolibrary.org/obo/CHEBI_48578) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [radical scavenger](http://purl.obolibrary.org/obo/CHEBI_48578) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A role played by a substance that can react readily with, and thereby eliminate, radicals." + +- Class: [radical scavenger](http://purl.obolibrary.org/obo/CHEBI_48578) + +- [radical scavenger](http://purl.obolibrary.org/obo/CHEBI_48578) SubClassOf [antioxidant](http://purl.obolibrary.org/obo/CHEBI_22586) + + + +### reactive nitrogen species `http://purl.obolibrary.org/obo/CHEBI_62764` +#### Removed +- [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17667957" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "SUBMITTER" + +- [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "RNI" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "SUBMITTER" + +- [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Reactive_nitrogen_species" + +- [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A family of nitrogen molecular entities which are highly reactive and derived from nitric oxide (.NO) and superoxide (O2.(-)) produced via the enzymatic activity of inducible nitric oxide synthase 2 (NOS2) and NADPH oxidase respectively." + +- [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12076975" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "SUBMITTER" + +- [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:62764" + +- [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764) [label](http://www.w3.org/2000/01/rdf-schema#label) "reactive nitrogen species" + +- [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9741578" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "SUBMITTER" + +- [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "RNS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "SUBMITTER" + +- [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764) + +- [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764) SubClassOf [nitrogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_51143) + + + +### reactive nitrogen species metabolic process `http://purl.obolibrary.org/obo/GO_2001057` +#### Removed +- [reactive nitrogen species metabolic process](http://purl.obolibrary.org/obo/GO_2001057) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [reactive nitrogen species metabolic process](http://purl.obolibrary.org/obo/GO_2001057) [label](http://www.w3.org/2000/01/rdf-schema#label) "reactive nitrogen species metabolic process" + +- [reactive nitrogen species metabolic process](http://purl.obolibrary.org/obo/GO_2001057) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2001057" + +- [reactive nitrogen species metabolic process](http://purl.obolibrary.org/obo/GO_2001057) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-09-09T01:29:13Z" + +- [reactive nitrogen species metabolic process](http://purl.obolibrary.org/obo/GO_2001057) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "RNS metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [reactive nitrogen species metabolic process](http://purl.obolibrary.org/obo/GO_2001057) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "jl" + +- [reactive nitrogen species metabolic process](http://purl.obolibrary.org/obo/GO_2001057) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving a reactive nitrogen species." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [reactive nitrogen species metabolic process](http://purl.obolibrary.org/obo/GO_2001057) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "reactive nitrogen species metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [reactive nitrogen species metabolic process](http://purl.obolibrary.org/obo/GO_2001057) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "RNS metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- Class: [reactive nitrogen species metabolic process](http://purl.obolibrary.org/obo/GO_2001057) + +- [reactive nitrogen species metabolic process](http://purl.obolibrary.org/obo/GO_2001057) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764)) + +- [reactive nitrogen species metabolic process](http://purl.obolibrary.org/obo/GO_2001057) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [reactive nitrogen species](http://purl.obolibrary.org/obo/CHEBI_62764) + +- [reactive nitrogen species metabolic process](http://purl.obolibrary.org/obo/GO_2001057) SubClassOf [nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0006807) + + + +### reactive oxygen species `http://purl.obolibrary.org/obo/CHEBI_26523` +#### Removed +- [reactive oxygen species](http://purl.obolibrary.org/obo/CHEBI_26523) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers." + +- [reactive oxygen species](http://purl.obolibrary.org/obo/CHEBI_26523) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26523" + +- [reactive oxygen species](http://purl.obolibrary.org/obo/CHEBI_26523) [label](http://www.w3.org/2000/01/rdf-schema#label) "reactive oxygen species" + +- [reactive oxygen species](http://purl.obolibrary.org/obo/CHEBI_26523) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [reactive oxygen species](http://purl.obolibrary.org/obo/CHEBI_26523) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Reactive_oxygen_species" + +- [reactive oxygen species](http://purl.obolibrary.org/obo/CHEBI_26523) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [reactive oxygen species](http://purl.obolibrary.org/obo/CHEBI_26523) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ROS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [reactive oxygen species](http://purl.obolibrary.org/obo/CHEBI_26523) + +- [reactive oxygen species](http://purl.obolibrary.org/obo/CHEBI_26523) SubClassOf [oxygen molecular entity](http://purl.obolibrary.org/obo/CHEBI_25806) + + + +### reactive oxygen species biosynthetic process `http://purl.obolibrary.org/obo/GO_1903409` +#### Removed +- [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "reactive oxygen species generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24252804" + +- [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "reactive oxygen species anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "reactive oxygen species formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-09-03T09:19:13Z" + +- [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "bf" + +- [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "reactive oxygen species synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "reactive oxygen species biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) [label](http://www.w3.org/2000/01/rdf-schema#label) "reactive oxygen species biosynthetic process" + +- [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ROS generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24252804" + +- [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1903409" + +- [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ROS formation" + +- [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:bf" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24252804" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:PARL" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000068" + +- Class: [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) + +- [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [reactive oxygen species](http://purl.obolibrary.org/obo/CHEBI_26523)) + +- [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [reactive oxygen species](http://purl.obolibrary.org/obo/CHEBI_26523) + +- [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + +- [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) SubClassOf [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593) + + + +### reactive oxygen species metabolic process `http://purl.obolibrary.org/obo/GO_0072593` +#### Removed +- [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-02-11T10:50:06Z" + +- [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593) [label](http://www.w3.org/2000/01/rdf-schema#label) "reactive oxygen species metabolic process" + +- [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ROS metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CHEBI:26523" + +- [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0072593" + +- [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "reactive oxygen species metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- Class: [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593) + +- [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [reactive oxygen species](http://purl.obolibrary.org/obo/CHEBI_26523)) + +- [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [reactive oxygen species](http://purl.obolibrary.org/obo/CHEBI_26523) + +- [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593) SubClassOf [cellular metabolic process](http://purl.obolibrary.org/obo/GO_0044237) + + + +### reagent `http://purl.obolibrary.org/obo/CHEBI_33893` +#### Removed +- [reagent](http://purl.obolibrary.org/obo/CHEBI_33893) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "reagents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [reagent](http://purl.obolibrary.org/obo/CHEBI_33893) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [reagent](http://purl.obolibrary.org/obo/CHEBI_33893) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "reactif" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [reagent](http://purl.obolibrary.org/obo/CHEBI_33893) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [reagent](http://purl.obolibrary.org/obo/CHEBI_33893) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A substance used in a chemical reaction to detect, measure, examine, or produce other substances." + +- [reagent](http://purl.obolibrary.org/obo/CHEBI_33893) [label](http://www.w3.org/2000/01/rdf-schema#label) "reagent" + +- [reagent](http://purl.obolibrary.org/obo/CHEBI_33893) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33893" + +- [reagent](http://purl.obolibrary.org/obo/CHEBI_33893) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "reagent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [reagent](http://purl.obolibrary.org/obo/CHEBI_33893) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "reactivo" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- Class: [reagent](http://purl.obolibrary.org/obo/CHEBI_33893) + +- [reagent](http://purl.obolibrary.org/obo/CHEBI_33893) SubClassOf [application](http://purl.obolibrary.org/obo/CHEBI_33232) + + + +### receives input from `http://purl.obolibrary.org/obo/RO_0002485` +#### Removed +- [receives input from](http://purl.obolibrary.org/obo/RO_0002485) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [receives input from](http://purl.obolibrary.org/obo/RO_0002485) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### receptor modulator `http://purl.obolibrary.org/obo/CHEBI_90710` +#### Removed +- [receptor modulator](http://purl.obolibrary.org/obo/CHEBI_90710) [label](http://www.w3.org/2000/01/rdf-schema#label) "receptor modulator" + +- [receptor modulator](http://purl.obolibrary.org/obo/CHEBI_90710) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [receptor modulator](http://purl.obolibrary.org/obo/CHEBI_90710) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "receptor modulators" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [receptor modulator](http://purl.obolibrary.org/obo/CHEBI_90710) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:90710" + +- [receptor modulator](http://purl.obolibrary.org/obo/CHEBI_90710) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [receptor modulator](http://purl.obolibrary.org/obo/CHEBI_90710) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors." + +- Class: [receptor modulator](http://purl.obolibrary.org/obo/CHEBI_90710) + +- [receptor modulator](http://purl.obolibrary.org/obo/CHEBI_90710) SubClassOf [drug](http://purl.obolibrary.org/obo/CHEBI_23888) + + + +### rectal salt gland `http://purl.obolibrary.org/obo/UBERON_0004757` +#### Removed +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [organ_slim](http://purl.obolibrary.org/obo/uberon/core#organ_slim) + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) [never in taxon](http://purl.obolibrary.org/obo/RO_0002161) [Tetrapoda](http://purl.obolibrary.org/obo/NCBITaxon_32523) + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0004757" + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An evagination of the terminal portion of the intestine that is capable of secreting high concentrations of excess sodium chloride." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UBERON:cjm" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://www.briancoad.com/dictionary/complete%20dictionary.htm" + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) [UBPROP_0000009](http://purl.obolibrary.org/obo/UBPROP_0000009) "shark liver produces copious amounts of urea, making the shark hyperosmotic to seawater, & thus a shark acts like a fresh water fish, constantly gaining water. Excess salts are concentrated by the rectal gland and secreted" + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "glandula rectalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://www.briancoad.com/dictionary/complete%20dictionary.htm" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "SCTID:80455007" + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001157" + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) [label](http://www.w3.org/2000/01/rdf-schema#label) "rectal salt gland" + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "rectal gland" + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [NCBITaxon_119203](http://purl.obolibrary.org/obo/NCBITaxon_119203) + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "digitiform gland" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://www.briancoad.com/dictionary/complete%20dictionary.htm" + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [NCBITaxon_118072](http://purl.obolibrary.org/obo/NCBITaxon_118072) + +- Class: [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) EquivalentTo [gland](http://purl.obolibrary.org/obo/UBERON_0002530) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [rectum](http://purl.obolibrary.org/obo/UBERON_0001052)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055078)) + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [rectum](http://purl.obolibrary.org/obo/UBERON_0001052) + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) SubClassOf [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Gnathostomata ](http://purl.obolibrary.org/obo/NCBITaxon_7776) + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) SubClassOf [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) + +- [rectal salt gland](http://purl.obolibrary.org/obo/UBERON_0004757) SubClassOf [gland of digestive tract](http://purl.obolibrary.org/obo/UBERON_0003408) + + + +### refrigerant `http://purl.obolibrary.org/obo/CHEBI_78433` +#### Removed +- [refrigerant](http://purl.obolibrary.org/obo/CHEBI_78433) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure." + +- [refrigerant](http://purl.obolibrary.org/obo/CHEBI_78433) [label](http://www.w3.org/2000/01/rdf-schema#label) "refrigerant" + +- [refrigerant](http://purl.obolibrary.org/obo/CHEBI_78433) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:78433" + +- [refrigerant](http://purl.obolibrary.org/obo/CHEBI_78433) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [refrigerant](http://purl.obolibrary.org/obo/CHEBI_78433) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Refrigerant" + +- [refrigerant](http://purl.obolibrary.org/obo/CHEBI_78433) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "refrigerants" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [refrigerant](http://purl.obolibrary.org/obo/CHEBI_78433) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [refrigerant](http://purl.obolibrary.org/obo/CHEBI_78433) + +- [refrigerant](http://purl.obolibrary.org/obo/CHEBI_78433) SubClassOf [application](http://purl.obolibrary.org/obo/CHEBI_33232) + + + +### regulated by `http://purl.obolibrary.org/obo/RO_0002334` +#### Removed +- [regulated by](http://purl.obolibrary.org/obo/RO_0002334) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [regulated by](http://purl.obolibrary.org/obo/RO_0002334) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### regulates `http://purl.obolibrary.org/obo/RO_0002211` +#### Removed +- [regulates](http://purl.obolibrary.org/obo/RO_0002211) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +- [regulates](http://purl.obolibrary.org/obo/RO_0002211) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Tanya Berardini" + +- [regulates](http://purl.obolibrary.org/obo/RO_0002211) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Hill" + +#### Added +- [regulates](http://purl.obolibrary.org/obo/RO_0002211) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + +- [regulates](http://purl.obolibrary.org/obo/RO_0002211) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0001-7476-6306](https://orcid.org/0000-0001-7476-6306) + +- [regulates](http://purl.obolibrary.org/obo/RO_0002211) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-3837-8864](https://orcid.org/0000-0002-3837-8864) + + +### regulates activity of `http://purl.obolibrary.org/obo/RO_0011002` +#### Removed +- [regulates activity of](http://purl.obolibrary.org/obo/RO_0011002) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Vasundra Touré" + +#### Added +- [regulates activity of](http://purl.obolibrary.org/obo/RO_0011002) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0003-4639-4431](https://orcid.org/0000-0003-4639-4431) + + +### regulates levels of `http://purl.obolibrary.org/obo/RO_0002332` +#### Removed +- [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### regulation of CD4 production `http://purl.obolibrary.org/obo/GO_0045223` + +#### Added +- [regulation of CD4 production](http://purl.obolibrary.org/obo/GO_0045223) SubClassOf [regulation of protein metabolic process](http://purl.obolibrary.org/obo/GO_0051246) + + +### regulation of DNA biosynthetic process `http://purl.obolibrary.org/obo/GO_2000278` +#### Removed +- [regulation of DNA biosynthetic process](http://purl.obolibrary.org/obo/GO_2000278) SubClassOf [regulation of macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0010556) + +- [regulation of DNA biosynthetic process](http://purl.obolibrary.org/obo/GO_2000278) SubClassOf [regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031326) + +#### Added +- [regulation of DNA biosynthetic process](http://purl.obolibrary.org/obo/GO_2000278) SubClassOf [regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009889) + + +### regulation of DNA catabolic process `http://purl.obolibrary.org/obo/GO_1903624` +#### Removed +- [regulation of DNA catabolic process](http://purl.obolibrary.org/obo/GO_1903624) SubClassOf [regulation of cellular catabolic process](http://purl.obolibrary.org/obo/GO_0031329) + +#### Added +- [regulation of DNA catabolic process](http://purl.obolibrary.org/obo/GO_1903624) SubClassOf [regulation of catabolic process](http://purl.obolibrary.org/obo/GO_0009894) + + +### regulation of DNA metabolic process `http://purl.obolibrary.org/obo/GO_0051052` +#### Removed +- [regulation of DNA metabolic process](http://purl.obolibrary.org/obo/GO_0051052) SubClassOf [regulation of nucleobase-containing compound metabolic process](http://purl.obolibrary.org/obo/GO_0019219) + + + +### regulation of RNA biosynthetic process `http://purl.obolibrary.org/obo/GO_2001141` +#### Removed +- [regulation of RNA biosynthetic process](http://purl.obolibrary.org/obo/GO_2001141) SubClassOf [regulation of macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0010556) + +- [regulation of RNA biosynthetic process](http://purl.obolibrary.org/obo/GO_2001141) SubClassOf [regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031326) + +#### Added +- [regulation of RNA biosynthetic process](http://purl.obolibrary.org/obo/GO_2001141) SubClassOf [regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009889) + + +### regulation of RNA metabolic process `http://purl.obolibrary.org/obo/GO_0051252` +#### Removed +- [regulation of RNA metabolic process](http://purl.obolibrary.org/obo/GO_0051252) SubClassOf [regulation of macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0060255) + +- [regulation of RNA metabolic process](http://purl.obolibrary.org/obo/GO_0051252) SubClassOf [regulation of nucleobase-containing compound metabolic process](http://purl.obolibrary.org/obo/GO_0019219) + +#### Added +- [regulation of RNA metabolic process](http://purl.obolibrary.org/obo/GO_0051252) SubClassOf [regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0019222) + + +### regulation of acetate catabolic process `http://purl.obolibrary.org/obo/GO_0045734` +#### Removed +- [regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045734) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045734) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of acetate catabolism" + +- [regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045734) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045734) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of acetate breakdown" + +- [regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045734) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of acetate catabolic process" + +- [regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045734) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of acetate degradation" + +- [regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045734) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0045734" + +- Class: [regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045734) + +- [regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045734) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733)) + +- [regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045734) SubClassOf [regulation of cellular ketone metabolic process](http://purl.obolibrary.org/obo/GO_0010565) + +- [regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045734) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045733) + +- [regulation of acetate catabolic process](http://purl.obolibrary.org/obo/GO_0045734) SubClassOf [regulation of cellular catabolic process](http://purl.obolibrary.org/obo/GO_0031329) + + + +### regulation of acetylcholine-gated cation channel activity `http://purl.obolibrary.org/obo/GO_1903048` + +#### Added +- [regulation of acetylcholine-gated cation channel activity](http://purl.obolibrary.org/obo/GO_1903048) SubClassOf [regulation of monoatomic ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0032412) + + +### regulation of alcohol biosynthetic process `http://purl.obolibrary.org/obo/GO_1902930` +#### Removed +- [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-04-22T21:55:03Z" + +- [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of alcohol synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of alcohol anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of alcohol formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of alcohol biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23332010" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "regulation of solventogenesis" + +- [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of alcohol biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902930" + +- [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of alcohol biosynthetic process" + +- Class: [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) + +- [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165)) + +- [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) SubClassOf [regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009889) + +- [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_0046165) + +- [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) SubClassOf [regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062012) + + + +### regulation of aldosterone biosynthetic process `http://purl.obolibrary.org/obo/GO_0032347` +#### Removed +- [regulation of aldosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_0032347) SubClassOf [regulation of alcohol biosynthetic process](http://purl.obolibrary.org/obo/GO_1902930) + + + +### regulation of alkane biosynthetic process `http://purl.obolibrary.org/obo/GO_1901577` +#### Removed +- [regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901577) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-11-05T21:54:06Z" + +- [regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901577) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of alkane biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901577) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of alkane synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901577) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of alkane biosynthetic process" + +- [regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901577) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "dhl" + +- [regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901577) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of alkane anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901577) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901577) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of alkane biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901577) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of alkane formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901577) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901577" + +- Class: [regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901577) + +- [regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901577) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447)) + +- [regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901577) SubClassOf [regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031326) + +- [regulation of alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_1901577) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [alkane biosynthetic process](http://purl.obolibrary.org/obo/GO_0043447) + + + +### regulation of amide metabolic process `http://purl.obolibrary.org/obo/GO_0034248` +#### Removed +- [regulation of amide metabolic process](http://purl.obolibrary.org/obo/GO_0034248) SubClassOf [regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051171) + +#### Added +- [regulation of amide metabolic process](http://purl.obolibrary.org/obo/GO_0034248) SubClassOf [regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0019222) + + +### regulation of amine metabolic process `http://purl.obolibrary.org/obo/GO_0033238` +#### Removed +- [regulation of amine metabolic process](http://purl.obolibrary.org/obo/GO_0033238) SubClassOf [regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051171) + +#### Added +- [regulation of amine metabolic process](http://purl.obolibrary.org/obo/GO_0033238) SubClassOf [regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0019222) + + +### regulation of amino acid transport `http://purl.obolibrary.org/obo/GO_0051955` +#### Removed +- [regulation of amino acid transport](http://purl.obolibrary.org/obo/GO_0051955) SubClassOf [regulation of organic acid transport](http://purl.obolibrary.org/obo/GO_0032890) + + + +### regulation of apolipoprotein binding `http://purl.obolibrary.org/obo/GO_2000656` +#### Removed +- [regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000656) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of apolipoprotein binding." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:BHF" + +- [regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000656) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of apolipoprotein binding" + +- [regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000656) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000656) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000656" + +- [regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000656) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "vk" + +- [regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000656) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-05-02T05:33:41Z" + +- Class: [regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000656) + +- [regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000656) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185)) + +- [regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000656) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [apolipoprotein binding](http://purl.obolibrary.org/obo/GO_0034185) + +- [regulation of apolipoprotein binding](http://purl.obolibrary.org/obo/GO_2000656) SubClassOf [regulation of protein binding](http://purl.obolibrary.org/obo/GO_0043393) + + + +### regulation of calcium ion transmembrane transport `http://purl.obolibrary.org/obo/GO_1903169` +#### Removed +- [regulation of calcium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903169) SubClassOf [regulation of monoatomic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_1904062) + +#### Added +- [regulation of calcium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903169) SubClassOf [regulation of transmembrane transport](http://purl.obolibrary.org/obo/GO_0034762) + + +### regulation of calcium ion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_1901019` +#### Removed +- [regulation of calcium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901019) SubClassOf [regulation of monoatomic ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0032412) + +#### Added +- [regulation of calcium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901019) SubClassOf [regulation of transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022898) + + +### regulation of calcium ion transport `http://purl.obolibrary.org/obo/GO_0051924` +#### Removed +- [regulation of calcium ion transport](http://purl.obolibrary.org/obo/GO_0051924) SubClassOf [regulation of metal ion transport](http://purl.obolibrary.org/obo/GO_0010959) + +#### Added +- [regulation of calcium ion transport](http://purl.obolibrary.org/obo/GO_0051924) SubClassOf [regulation of transport](http://purl.obolibrary.org/obo/GO_0051049) + + +### regulation of cation channel activity `http://purl.obolibrary.org/obo/GO_2001257` +#### Removed +- [regulation of cation channel activity](http://purl.obolibrary.org/obo/GO_2001257) SubClassOf [regulation of monoatomic ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0032412) + +#### Added +- [regulation of cation channel activity](http://purl.obolibrary.org/obo/GO_2001257) SubClassOf [regulation of transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022898) + + +### regulation of cellular amino acid biosynthetic process `http://purl.obolibrary.org/obo/GO_2000282` +#### Removed +- [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) SubClassOf [regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031326) + +#### Added +- [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) SubClassOf [regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009889) + + +### regulation of cellular amino acid metabolic process `http://purl.obolibrary.org/obo/GO_0006521` + +#### Added +- [regulation of cellular amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0006521) SubClassOf [regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051171) + + +### regulation of cellular carbohydrate catabolic process `http://purl.obolibrary.org/obo/GO_0043471` +#### Removed +- [regulation of cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0043471) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0043471" + +- [regulation of cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0043471) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates, carried out by individual cells." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [regulation of cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0043471) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0043471) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of cellular carbohydrate catabolic process" + +- Class: [regulation of cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0043471) + +- [regulation of cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0043471) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0044275)) + +- [regulation of cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0043471) SubClassOf [regulation of cellular catabolic process](http://purl.obolibrary.org/obo/GO_0031329) + +- [regulation of cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0043471) SubClassOf [regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010675) + +- [regulation of cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0043471) SubClassOf [regulation of carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0043470) + +- [regulation of cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0043471) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0044275) + +- [regulation of cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0043471) SubClassOf [regulation of macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0060255) + + + +### regulation of cellular carbohydrate metabolic process `http://purl.obolibrary.org/obo/GO_0010675` +#### Removed +- [regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010675) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010675) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of cellular carbohydrate metabolic process" + +- [regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010675) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0010675" + +- [regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010675) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010675) + +- [regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010675) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262)) + +- [regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010675) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0044262) + +- [regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010675) SubClassOf [regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031323) + +- [regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010675) SubClassOf [regulation of carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0006109) + + + +### regulation of cellular macromolecule biosynthetic process `http://purl.obolibrary.org/obo/GO_2000112` +#### Removed +- [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-09-15T08:55:45Z" + +- [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of cellular macromolecule biosynthetic process" + +- [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of cellular macromolecule synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of cellular biopolymer biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of cellular macromolecule biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of cellular macromolecule formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000112" + +- [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of cellular macromolecule anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tb" + +- Class: [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) + +- [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645)) + +- [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) + +- [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) SubClassOf [regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031326) + +- [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) SubClassOf [regulation of macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0010556) + + + +### regulation of cellular response to alcohol `http://purl.obolibrary.org/obo/GO_1905957` +#### Removed +- [regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905957) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1905957" + +- [regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905957) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of cellular response to alcohol." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:26434723" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + +- [regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905957) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of cellular response to alcohol" + +- [regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905957) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2017-02-22T12:03:00Z" + +- [regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905957) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905957) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "hbye" + +- Class: [regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905957) + +- [regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905957) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306)) + +- [regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905957) SubClassOf [regulation of cellular process](http://purl.obolibrary.org/obo/GO_0050794) + +- [regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905957) SubClassOf [regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901419) + +- [regulation of cellular response to alcohol](http://purl.obolibrary.org/obo/GO_1905957) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [cellular response to alcohol](http://purl.obolibrary.org/obo/GO_0097306) + + + +### regulation of cellular response to oxidative stress `http://purl.obolibrary.org/obo/GO_1900407` +#### Removed +- [regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900407) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "regulation of adaptive response to oxidative stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900407) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-04-20T03:30:52Z" + +- [regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900407) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1900407" + +- [regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900407) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of cellular response to oxidative stress" + +- [regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900407) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of cellular response to oxidative stress." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900407) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900407) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- Class: [regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900407) + +- [regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900407) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599)) + +- [regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900407) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599) + +- [regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900407) SubClassOf [regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902882) + +- [regulation of cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_1900407) SubClassOf [regulation of cellular response to stress](http://purl.obolibrary.org/obo/GO_0080135) + + + +### regulation of cellular response to stress `http://purl.obolibrary.org/obo/GO_0080135` +#### Removed +- [regulation of cellular response to stress](http://purl.obolibrary.org/obo/GO_0080135) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "dhl" + +- [regulation of cellular response to stress](http://purl.obolibrary.org/obo/GO_0080135) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0080135" + +- [regulation of cellular response to stress](http://purl.obolibrary.org/obo/GO_0080135) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of cellular response to stress](http://purl.obolibrary.org/obo/GO_0080135) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dhl" + +- [regulation of cellular response to stress](http://purl.obolibrary.org/obo/GO_0080135) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of cellular response to stress" + +- [regulation of cellular response to stress](http://purl.obolibrary.org/obo/GO_0080135) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2009-05-06T05:02:52Z" + +- Class: [regulation of cellular response to stress](http://purl.obolibrary.org/obo/GO_0080135) + +- [regulation of cellular response to stress](http://purl.obolibrary.org/obo/GO_0080135) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [cellular response to stress](http://purl.obolibrary.org/obo/GO_0033554)) + +- [regulation of cellular response to stress](http://purl.obolibrary.org/obo/GO_0080135) SubClassOf [regulation of cellular process](http://purl.obolibrary.org/obo/GO_0050794) + +- [regulation of cellular response to stress](http://purl.obolibrary.org/obo/GO_0080135) SubClassOf [regulation of response to stress](http://purl.obolibrary.org/obo/GO_0080134) + +- [regulation of cellular response to stress](http://purl.obolibrary.org/obo/GO_0080135) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [cellular response to stress](http://purl.obolibrary.org/obo/GO_0033554) + + + +### regulation of dopamine metabolic process `http://purl.obolibrary.org/obo/GO_0042053` +#### Removed +- [regulation of dopamine metabolic process](http://purl.obolibrary.org/obo/GO_0042053) SubClassOf [regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051171) + +#### Added +- [regulation of dopamine metabolic process](http://purl.obolibrary.org/obo/GO_0042053) SubClassOf [regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0019222) + + +### regulation of ecdysteroid metabolic process `http://purl.obolibrary.org/obo/GO_0007553` +#### Removed +- [regulation of ecdysteroid metabolic process](http://purl.obolibrary.org/obo/GO_0007553) SubClassOf [regulation of steroid metabolic process](http://purl.obolibrary.org/obo/GO_0019218) + + + +### regulation of epinephrine secretion `http://purl.obolibrary.org/obo/GO_0014060` +#### Removed +- [regulation of epinephrine secretion](http://purl.obolibrary.org/obo/GO_0014060) SubClassOf [regulation of catecholamine secretion](http://purl.obolibrary.org/obo/GO_0050433) + +#### Added +- [regulation of epinephrine secretion](http://purl.obolibrary.org/obo/GO_0014060) SubClassOf [regulation of secretion](http://purl.obolibrary.org/obo/GO_0051046) + + +### regulation of estrogen secretion `http://purl.obolibrary.org/obo/GO_2000861` +#### Removed +- [regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000861) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "regulation of oestrogen secretion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000861) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of estrogen secretion." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:sl" + +- [regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000861) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-07-26T08:48:24Z" + +- [regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000861) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of estrogen secretion" + +- [regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000861) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000861) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000861" + +- [regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000861) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "bf" + +- Class: [regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000861) + +- [regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000861) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [estrogen secretion](http://purl.obolibrary.org/obo/GO_0035937)) + +- [regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000861) SubClassOf [regulation of steroid hormone secretion](http://purl.obolibrary.org/obo/GO_2000831) + +- [regulation of estrogen secretion](http://purl.obolibrary.org/obo/GO_2000861) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [estrogen secretion](http://purl.obolibrary.org/obo/GO_0035937) + + + +### regulation of fatty acid biosynthetic process `http://purl.obolibrary.org/obo/GO_0042304` +#### Removed +- [regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042304) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of fatty acid biosynthetic process" + +- [regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042304) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of fatty acid anabolism" + +- [regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042304) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of fatty acid formation" + +- [regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042304) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042304) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of fatty acid synthesis" + +- [regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042304) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042304) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of fatty acid biosynthesis" + +- [regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042304) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0042304" + +- Class: [regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042304) + +- [regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042304) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633)) + +- [regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042304) SubClassOf [regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0019217) + +- [regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042304) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) + +- [regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042304) SubClassOf [regulation of lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046890) + +- [regulation of fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0042304) SubClassOf [regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031326) + + + +### regulation of fatty acid metabolic process `http://purl.obolibrary.org/obo/GO_0019217` +#### Removed +- [regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0019217) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of fatty acid metabolic process" + +- [regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0019217) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0006632" + +- [regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0019217) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of fatty acid metabolism" + +- [regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0019217) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0019217) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0019217) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0019217" + +- Class: [regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0019217) + +- [regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0019217) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631)) + +- [regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0019217) SubClassOf [regulation of lipid metabolic process](http://purl.obolibrary.org/obo/GO_0019216) + +- [regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0019217) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631) + +- [regulation of fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0019217) SubClassOf [regulation of cellular ketone metabolic process](http://purl.obolibrary.org/obo/GO_0010565) + + + +### regulation of fatty acid transport `http://purl.obolibrary.org/obo/GO_2000191` +#### Removed +- [regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000191) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000191) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of fatty acid transport" + +- [regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000191) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-10-18T10:37:13Z" + +- [regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000191) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000191" + +- [regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000191) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "rl" + +- [regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000191) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of fatty acid transport." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:BHF" + +- Class: [regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000191) + +- [regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000191) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908)) + +- [regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000191) SubClassOf [regulation of lipid transport](http://purl.obolibrary.org/obo/GO_0032368) + +- [regulation of fatty acid transport](http://purl.obolibrary.org/obo/GO_2000191) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908) + + + +### regulation of fermentation `http://purl.obolibrary.org/obo/GO_0043465` +#### Removed +- [regulation of fermentation](http://purl.obolibrary.org/obo/GO_0043465) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of fermentation" + +- [regulation of fermentation](http://purl.obolibrary.org/obo/GO_0043465) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of fermentation, the anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, resulting in energy in the form of adenosine triphosphate (ATP)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [regulation of fermentation](http://purl.obolibrary.org/obo/GO_0043465) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of fermentation](http://purl.obolibrary.org/obo/GO_0043465) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0043465" + +- Class: [regulation of fermentation](http://purl.obolibrary.org/obo/GO_0043465) + +- [regulation of fermentation](http://purl.obolibrary.org/obo/GO_0043465) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [fermentation](http://purl.obolibrary.org/obo/GO_0006113)) + +- [regulation of fermentation](http://purl.obolibrary.org/obo/GO_0043465) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [fermentation](http://purl.obolibrary.org/obo/GO_0006113) + +- [regulation of fermentation](http://purl.obolibrary.org/obo/GO_0043465) SubClassOf [regulation of generation of precursor metabolites and energy](http://purl.obolibrary.org/obo/GO_0043467) + + + +### regulation of glucan biosynthetic process `http://purl.obolibrary.org/obo/GO_0010962` +#### Removed +- [regulation of glucan biosynthetic process](http://purl.obolibrary.org/obo/GO_0010962) SubClassOf [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) + +- [regulation of glucan biosynthetic process](http://purl.obolibrary.org/obo/GO_0010962) SubClassOf [regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010675) + + + +### regulation of glucocorticoid catabolic process `http://purl.obolibrary.org/obo/GO_0031949` +#### Removed +- [regulation of glucocorticoid catabolic process](http://purl.obolibrary.org/obo/GO_0031949) SubClassOf [regulation of lipid catabolic process](http://purl.obolibrary.org/obo/GO_0050994) + + + +### regulation of gluconeogenesis `http://purl.obolibrary.org/obo/GO_0006111` +#### Removed +- [regulation of gluconeogenesis](http://purl.obolibrary.org/obo/GO_0006111) SubClassOf [regulation of carbohydrate biosynthetic process](http://purl.obolibrary.org/obo/GO_0043255) + +#### Added +- [regulation of gluconeogenesis](http://purl.obolibrary.org/obo/GO_0006111) SubClassOf [regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009889) + + +### regulation of glucose metabolic process `http://purl.obolibrary.org/obo/GO_0010906` +#### Removed +- [regulation of glucose metabolic process](http://purl.obolibrary.org/obo/GO_0010906) SubClassOf [regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062012) + +- [regulation of glucose metabolic process](http://purl.obolibrary.org/obo/GO_0010906) SubClassOf [regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010675) + +#### Added +- [regulation of glucose metabolic process](http://purl.obolibrary.org/obo/GO_0010906) SubClassOf [regulation of carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0006109) + + +### regulation of glycogen catabolic process `http://purl.obolibrary.org/obo/GO_0005981` +#### Removed +- [regulation of glycogen catabolic process](http://purl.obolibrary.org/obo/GO_0005981) SubClassOf [regulation of cellular carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0043471) + +#### Added +- [regulation of glycogen catabolic process](http://purl.obolibrary.org/obo/GO_0005981) SubClassOf [regulation of carbohydrate catabolic process](http://purl.obolibrary.org/obo/GO_0043470) + + +### regulation of glycogen metabolic process `http://purl.obolibrary.org/obo/GO_0070873` +#### Removed +- [regulation of glycogen metabolic process](http://purl.obolibrary.org/obo/GO_0070873) SubClassOf [regulation of cellular carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0010675) + + + +### regulation of glycoprotein biosynthetic process `http://purl.obolibrary.org/obo/GO_0010559` +#### Removed +- [regulation of glycoprotein biosynthetic process](http://purl.obolibrary.org/obo/GO_0010559) SubClassOf [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) + +#### Added +- [regulation of glycoprotein biosynthetic process](http://purl.obolibrary.org/obo/GO_0010559) SubClassOf [regulation of macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0010556) + + +### regulation of glycoprotein metabolic process `http://purl.obolibrary.org/obo/GO_1903018` +#### Removed +- [regulation of glycoprotein metabolic process](http://purl.obolibrary.org/obo/GO_1903018) SubClassOf [regulation of protein metabolic process](http://purl.obolibrary.org/obo/GO_0051246) + +- [regulation of glycoprotein metabolic process](http://purl.obolibrary.org/obo/GO_1903018) SubClassOf [regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031323) + +#### Added +- [regulation of glycoprotein metabolic process](http://purl.obolibrary.org/obo/GO_1903018) SubClassOf [regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0019222) + + +### regulation of hyaluronan biosynthetic process `http://purl.obolibrary.org/obo/GO_1900125` +#### Removed +- [regulation of hyaluronan biosynthetic process](http://purl.obolibrary.org/obo/GO_1900125) SubClassOf [regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051171) + + + +### regulation of inorganic anion transmembrane transport `http://purl.obolibrary.org/obo/GO_1903795` +#### Removed +- [regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903795) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11336802" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + +- [regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903795) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of inorganic anion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903795) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2015-01-14T21:44:49Z" + +- [regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903795) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of inorganic anion transmembrane transport" + +- [regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903795) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of transmembrane inorganic anion transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903795) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1903795" + +- [regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903795) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "sl" + +- [regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903795) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903795) + +- [regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903795) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661)) + +- [regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903795) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661) + +- [regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903795) SubClassOf [regulation of transmembrane transport](http://purl.obolibrary.org/obo/GO_0034762) + + + +### regulation of iron ion transmembrane transport `http://purl.obolibrary.org/obo/GO_0034759` +#### Removed +- [regulation of iron ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0034759) SubClassOf [regulation of monoatomic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_1904062) + +#### Added +- [regulation of iron ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0034759) SubClassOf [regulation of transmembrane transport](http://purl.obolibrary.org/obo/GO_0034762) + + +### regulation of iron ion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_1904254` +#### Removed +- [regulation of iron ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1904254) SubClassOf [regulation of monoatomic ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0032412) + +#### Added +- [regulation of iron ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1904254) SubClassOf [regulation of transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022898) + + +### regulation of iron ion transport `http://purl.obolibrary.org/obo/GO_0034756` +#### Removed +- [regulation of iron ion transport](http://purl.obolibrary.org/obo/GO_0034756) SubClassOf [regulation of metal ion transport](http://purl.obolibrary.org/obo/GO_0010959) + +#### Added +- [regulation of iron ion transport](http://purl.obolibrary.org/obo/GO_0034756) SubClassOf [regulation of transport](http://purl.obolibrary.org/obo/GO_0051049) + + +### regulation of isoprenoid metabolic process `http://purl.obolibrary.org/obo/GO_0019747` +#### Removed +- [regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0019747) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of isoprenoid metabolism" + +- [regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0019747) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0019747) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0019747" + +- [regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0019747) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of isoprenoid metabolic process" + +- [regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0019747) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- Class: [regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0019747) + +- [regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0019747) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720)) + +- [regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0019747) SubClassOf [regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031323) + +- [regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0019747) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) + +- [regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0019747) SubClassOf [regulation of lipid metabolic process](http://purl.obolibrary.org/obo/GO_0019216) + + + +### regulation of juvenile hormone biosynthetic process `http://purl.obolibrary.org/obo/GO_0007557` +#### Removed +- [regulation of juvenile hormone biosynthetic process](http://purl.obolibrary.org/obo/GO_0007557) SubClassOf [regulation of lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046890) + + + +### regulation of juvenile hormone catabolic process `http://purl.obolibrary.org/obo/GO_0045952` +#### Removed +- [regulation of juvenile hormone catabolic process](http://purl.obolibrary.org/obo/GO_0045952) SubClassOf [regulation of cellular catabolic process](http://purl.obolibrary.org/obo/GO_0031329) + +- [regulation of juvenile hormone catabolic process](http://purl.obolibrary.org/obo/GO_0045952) SubClassOf [regulation of lipid catabolic process](http://purl.obolibrary.org/obo/GO_0050994) + +#### Added +- [regulation of juvenile hormone catabolic process](http://purl.obolibrary.org/obo/GO_0045952) SubClassOf [regulation of catabolic process](http://purl.obolibrary.org/obo/GO_0009894) + + +### regulation of juvenile hormone metabolic process `http://purl.obolibrary.org/obo/GO_0007556` +#### Removed +- [regulation of juvenile hormone metabolic process](http://purl.obolibrary.org/obo/GO_0007556) SubClassOf [regulation of isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0019747) + + + +### regulation of juvenile hormone secretion `http://purl.obolibrary.org/obo/GO_0007558` +#### Removed +- [regulation of juvenile hormone secretion](http://purl.obolibrary.org/obo/GO_0007558) SubClassOf [regulation of lipid transport](http://purl.obolibrary.org/obo/GO_0032368) + + + +### regulation of lipoprotein metabolic process `http://purl.obolibrary.org/obo/GO_0050746` +#### Removed +- [regulation of lipoprotein metabolic process](http://purl.obolibrary.org/obo/GO_0050746) SubClassOf [regulation of protein metabolic process](http://purl.obolibrary.org/obo/GO_0051246) + + + +### regulation of lipoprotein transport `http://purl.obolibrary.org/obo/GO_0140075` +#### Removed +- [regulation of lipoprotein transport](http://purl.obolibrary.org/obo/GO_0140075) SubClassOf [regulation of protein transport](http://purl.obolibrary.org/obo/GO_0051223) + +#### Added +- [regulation of lipoprotein transport](http://purl.obolibrary.org/obo/GO_0140075) SubClassOf [regulation of transport](http://purl.obolibrary.org/obo/GO_0051049) + + +### regulation of membrane lipid metabolic process `http://purl.obolibrary.org/obo/GO_1905038` +#### Removed +- [regulation of membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_1905038) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1905038" + +- [regulation of membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_1905038) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tb" + +- [regulation of membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_1905038) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of membrane lipid metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_1905038) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2016-03-08T20:41:32Z" + +- [regulation of membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_1905038) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of membrane lipid metabolic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25954280" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + +- [regulation of membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_1905038) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of membrane lipid metabolic process" + +- [regulation of membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_1905038) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [regulation of membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_1905038) + +- [regulation of membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_1905038) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_0006643)) + +- [regulation of membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_1905038) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_0006643) + +- [regulation of membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_1905038) SubClassOf [regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031323) + +- [regulation of membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_1905038) SubClassOf [regulation of lipid metabolic process](http://purl.obolibrary.org/obo/GO_0019216) + + + +### regulation of metal ion transport `http://purl.obolibrary.org/obo/GO_0010959` +#### Removed +- [regulation of metal ion transport](http://purl.obolibrary.org/obo/GO_0010959) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tb" + +- [regulation of metal ion transport](http://purl.obolibrary.org/obo/GO_0010959) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of metal ion transport](http://purl.obolibrary.org/obo/GO_0010959) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2009-05-06T11:40:55Z" + +- [regulation of metal ion transport](http://purl.obolibrary.org/obo/GO_0010959) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0010959" + +- [regulation of metal ion transport](http://purl.obolibrary.org/obo/GO_0010959) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of metal ion transport" + +- [regulation of metal ion transport](http://purl.obolibrary.org/obo/GO_0010959) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- Class: [regulation of metal ion transport](http://purl.obolibrary.org/obo/GO_0010959) + +- [regulation of metal ion transport](http://purl.obolibrary.org/obo/GO_0010959) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001)) + +- [regulation of metal ion transport](http://purl.obolibrary.org/obo/GO_0010959) SubClassOf [regulation of monoatomic ion transport](http://purl.obolibrary.org/obo/GO_0043269) + +- [regulation of metal ion transport](http://purl.obolibrary.org/obo/GO_0010959) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) + + + +### regulation of monoatomic cation transmembrane transport `http://purl.obolibrary.org/obo/GO_1904062` +#### Removed +- [regulation of monoatomic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_1904062) SubClassOf [regulation of monoatomic ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0034765) + +#### Added +- [regulation of monoatomic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_1904062) SubClassOf [regulation of transmembrane transport](http://purl.obolibrary.org/obo/GO_0034762) + + +### regulation of nitric oxide biosynthetic process `http://purl.obolibrary.org/obo/GO_0045428` + +#### Added +- [regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045428) SubClassOf [regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051171) + + +### regulation of nitric oxide metabolic process `http://purl.obolibrary.org/obo/GO_0080164` +#### Removed +- [regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0080164) SubClassOf [regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051171) + +#### Added +- [regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0080164) SubClassOf [regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0019222) + + +### regulation of peptide hormone processing `http://purl.obolibrary.org/obo/GO_0060568` +#### Removed +- [regulation of peptide hormone processing](http://purl.obolibrary.org/obo/GO_0060568) SubClassOf [regulation of amide metabolic process](http://purl.obolibrary.org/obo/GO_0034248) + + + +### regulation of phagocytosis `http://purl.obolibrary.org/obo/GO_0050764` +#### Removed +- [regulation of phagocytosis](http://purl.obolibrary.org/obo/GO_0050764) SubClassOf [regulation of vesicle-mediated transport](http://purl.obolibrary.org/obo/GO_0060627) + +#### Added +- [regulation of phagocytosis](http://purl.obolibrary.org/obo/GO_0050764) SubClassOf [regulation of endocytosis](http://purl.obolibrary.org/obo/GO_0030100) + + +### regulation of phosphate metabolic process `http://purl.obolibrary.org/obo/GO_0019220` +#### Removed +- [regulation of phosphate metabolic process](http://purl.obolibrary.org/obo/GO_0019220) SubClassOf [regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0051174) + +#### Added +- [regulation of phosphate metabolic process](http://purl.obolibrary.org/obo/GO_0019220) SubClassOf [regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0019222) + + +### regulation of phosphate transmembrane transport `http://purl.obolibrary.org/obo/GO_2000185` +#### Removed +- [regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000185) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "vw" + +- [regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000185) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of phosphate membrane transport" + +- [regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000185) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000185) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of phosphate transmembrane transport" + +- [regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000185) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000185" + +- [regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000185) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of phosphate transmembrane transport." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000185) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-10-15T11:33:04Z" + +- Class: [regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000185) + +- [regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000185) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435)) + +- [regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000185) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [phosphate ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035435) + +- [regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000185) SubClassOf [regulation of phosphate transport](http://purl.obolibrary.org/obo/GO_0010966) + +- [regulation of phosphate transmembrane transport](http://purl.obolibrary.org/obo/GO_2000185) SubClassOf [regulation of inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_1903795) + + + +### regulation of phosphate transport `http://purl.obolibrary.org/obo/GO_0010966` +#### Removed +- [regulation of phosphate transport](http://purl.obolibrary.org/obo/GO_0010966) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [regulation of phosphate transport](http://purl.obolibrary.org/obo/GO_0010966) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of phosphate transport](http://purl.obolibrary.org/obo/GO_0010966) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0010966" + +- [regulation of phosphate transport](http://purl.obolibrary.org/obo/GO_0010966) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tb" + +- [regulation of phosphate transport](http://purl.obolibrary.org/obo/GO_0010966) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2009-05-20T11:42:50Z" + +- [regulation of phosphate transport](http://purl.obolibrary.org/obo/GO_0010966) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of phosphate transport" + +- Class: [regulation of phosphate transport](http://purl.obolibrary.org/obo/GO_0010966) + +- [regulation of phosphate transport](http://purl.obolibrary.org/obo/GO_0010966) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [phosphate ion transport](http://purl.obolibrary.org/obo/GO_0006817)) + +- [regulation of phosphate transport](http://purl.obolibrary.org/obo/GO_0010966) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [phosphate ion transport](http://purl.obolibrary.org/obo/GO_0006817) + +- [regulation of phosphate transport](http://purl.obolibrary.org/obo/GO_0010966) SubClassOf [regulation of transport](http://purl.obolibrary.org/obo/GO_0051049) + + + +### regulation of phosphorus metabolic process `http://purl.obolibrary.org/obo/GO_0051174` +#### Removed +- [regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0051174) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of phosphorus metabolism" + +- [regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0051174) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0051174) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0051174) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of phosphorus metabolic process" + +- [regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0051174) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0051174" + +- Class: [regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0051174) + +- [regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0051174) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0006793)) + +- [regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0051174) SubClassOf [regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031323) + +- [regulation of phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0051174) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [phosphorus metabolic process](http://purl.obolibrary.org/obo/GO_0006793) + + + +### regulation of progesterone biosynthetic process `http://purl.obolibrary.org/obo/GO_2000182` +#### Removed +- [regulation of progesterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000182) SubClassOf [regulation of steroid biosynthetic process](http://purl.obolibrary.org/obo/GO_0050810) + +- [regulation of progesterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000182) SubClassOf [regulation of hormone biosynthetic process](http://purl.obolibrary.org/obo/GO_0046885) + +- [regulation of progesterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000182) SubClassOf [regulation of ketone biosynthetic process](http://purl.obolibrary.org/obo/GO_0010566) + +#### Added +- [regulation of progesterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000182) SubClassOf [regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009889) + + +### regulation of protein metabolic process `http://purl.obolibrary.org/obo/GO_0051246` +#### Removed +- [regulation of protein metabolic process](http://purl.obolibrary.org/obo/GO_0051246) SubClassOf [regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051171) + +- [regulation of protein metabolic process](http://purl.obolibrary.org/obo/GO_0051246) SubClassOf [regulation of macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0060255) + + + +### regulation of protein modification process `http://purl.obolibrary.org/obo/GO_0031399` + +#### Added +- [regulation of protein modification process](http://purl.obolibrary.org/obo/GO_0031399) SubClassOf [regulation of macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0060255) + + +### regulation of reactive oxygen species biosynthetic process `http://purl.obolibrary.org/obo/GO_1903426` +#### Removed +- [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of reactive oxygen species formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-09-11T10:01:47Z" + +- [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of reactive oxygen species biosynthetic process" + +- [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1903426" + +- [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of reactive oxygen species synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "regulation of ROS generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:bf" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24252804" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:PARL" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + +- [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "bf" + +- [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of reactive oxygen species biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "regulation of ROS formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of reactive oxygen species anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "regulation of reactive oxygen species generation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) + +- [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409)) + +- [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) SubClassOf [regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000377) + +- [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) SubClassOf [regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009889) + +- [regulation of reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903426) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [reactive oxygen species biosynthetic process](http://purl.obolibrary.org/obo/GO_1903409) + + + +### regulation of reactive oxygen species metabolic process `http://purl.obolibrary.org/obo/GO_2000377` +#### Removed +- [regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000377) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of ROS metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000377) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- [regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000377) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000377) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000377" + +- [regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000377) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-02-11T02:06:36Z" + +- [regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000377) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of reactive oxygen species metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000377) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000377) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of reactive oxygen species metabolic process" + +- Class: [regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000377) + +- [regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000377) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593)) + +- [regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000377) SubClassOf [regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031323) + +- [regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000377) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593) + + + +### regulation of response to acetate `http://purl.obolibrary.org/obo/GO_1901457` +#### Removed +- [regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901457) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of response to acetate" + +- [regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901457) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901457" + +- [regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901457) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901457) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901457) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-02T14:25:06Z" + +- [regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901457) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of response to acetate." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- Class: [regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901457) + +- [regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901457) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [response to acetate](http://purl.obolibrary.org/obo/GO_0010034)) + +- [regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901457) SubClassOf [regulation of response to stimulus](http://purl.obolibrary.org/obo/GO_0048583) + +- [regulation of response to acetate](http://purl.obolibrary.org/obo/GO_1901457) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [response to acetate](http://purl.obolibrary.org/obo/GO_0010034) + + + +### regulation of response to alcohol `http://purl.obolibrary.org/obo/GO_1901419` +#### Removed +- [regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901419) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of response to alcohol" + +- [regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901419) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-01T16:52:13Z" + +- [regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901419) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901419) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of response to alcohol." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901419) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901419" + +- [regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901419) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- Class: [regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901419) + +- [regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901419) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305)) + +- [regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901419) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) + +- [regulation of response to alcohol](http://purl.obolibrary.org/obo/GO_1901419) SubClassOf [regulation of response to stimulus](http://purl.obolibrary.org/obo/GO_0048583) + + + +### regulation of response to formic acid `http://purl.obolibrary.org/obo/GO_1901460` +#### Removed +- [regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901460) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-02T14:27:54Z" + +- [regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901460) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901460) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of response to formic acid." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901460) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of response to formic acid" + +- [regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901460) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901460" + +- [regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901460) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901460) + +- [regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901460) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [response to formic acid](http://purl.obolibrary.org/obo/GO_1901425)) + +- [regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901460) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [response to formic acid](http://purl.obolibrary.org/obo/GO_1901425) + +- [regulation of response to formic acid](http://purl.obolibrary.org/obo/GO_1901460) SubClassOf [regulation of response to stimulus](http://purl.obolibrary.org/obo/GO_0048583) + + + +### regulation of response to oxidative stress `http://purl.obolibrary.org/obo/GO_1902882` +#### Removed +- [regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902882) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-04-03T20:29:52Z" + +- [regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902882) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of response to oxidative stress" + +- [regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902882) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of response to oxidative stress." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16899554" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:kmv" + +- [regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902882) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902882" + +- [regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902882) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "kmv" + +- [regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902882) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902882) + +- [regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902882) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [response to oxidative stress](http://purl.obolibrary.org/obo/GO_0006979)) + +- [regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902882) SubClassOf [regulation of response to stress](http://purl.obolibrary.org/obo/GO_0080134) + +- [regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902882) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [response to oxidative stress](http://purl.obolibrary.org/obo/GO_0006979) + + + +### regulation of response to reactive oxygen species `http://purl.obolibrary.org/obo/GO_1901031` +#### Removed +- [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of response to ROS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of response to active oxygen species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "kmv" + +- [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of response to reactive oxidative species" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901031" + +- [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of response to reactive oxygen species." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:kmv" + +- [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of response to reactive oxygen species" + +- [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of response to AOS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of response to reactive oxygen intermediate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-06-20T07:47:06Z" + +- [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of response to ROI" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) + +- [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302)) + +- [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) + +- [regulation of response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_1901031) SubClassOf [regulation of response to oxidative stress](http://purl.obolibrary.org/obo/GO_1902882) + + + +### regulation of secondary metabolite biosynthetic process `http://purl.obolibrary.org/obo/GO_1900376` +#### Removed +- [regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900376) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900376) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:di" + +- [regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900376) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "di" + +- [regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900376) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of secondary metabolite biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900376) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-04-17T01:55:23Z" + +- [regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900376) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1900376" + +- [regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900376) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of secondary metabolite biosynthetic process" + +- Class: [regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900376) + +- [regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900376) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550)) + +- [regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900376) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550) + +- [regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900376) SubClassOf [regulation of secondary metabolic process](http://purl.obolibrary.org/obo/GO_0043455) + +- [regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900376) SubClassOf [regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009889) + + + +### regulation of sodium ion transmembrane transport `http://purl.obolibrary.org/obo/GO_1902305` +#### Removed +- [regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902305) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of sodium ion transmembrane transport" + +- [regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902305) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "rl" + +- [regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902305) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2013-07-18T13:33:53Z" + +- [regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902305) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902305" + +- [regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902305) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902305) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_cardiac_conduct_nov11" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:rl" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:BHF" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18591664" + +- [regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902305) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of sodium ion membrane transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902305) + +- [regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902305) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725)) + +- [regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902305) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725) + +- [regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902305) SubClassOf [regulation of monoatomic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_1904062) + +- [regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902305) SubClassOf [regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0002028) + + + +### regulation of sodium ion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_2000649` +#### Removed +- [regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000649) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "yaf" + +- [regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000649) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of sodium ion transmembrane transporter activity" + +- [regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000649) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000649) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000649" + +- [regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000649) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of sodium transporter activity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000649) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-04-28T08:42:53Z" + +- [regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000649) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- Class: [regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000649) + +- [regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000649) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081)) + +- [regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000649) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081) + +- [regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000649) SubClassOf [regulation of monoatomic ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0032412) + +- [regulation of sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_2000649) SubClassOf [regulation of sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_1902305) + + + +### regulation of sodium ion transport `http://purl.obolibrary.org/obo/GO_0002028` +#### Removed +- [regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0002028) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of Na+ transport" + +- [regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0002028) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0002028" + +- [regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0002028) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0002028) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + +- [regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0002028) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of sodium ion transport" + +- [regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0002028) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of sodium transport" + +- Class: [regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0002028) + +- [regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0002028) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814)) + +- [regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0002028) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) + +- [regulation of sodium ion transport](http://purl.obolibrary.org/obo/GO_0002028) SubClassOf [regulation of metal ion transport](http://purl.obolibrary.org/obo/GO_0010959) + + + +### regulation of sphingolipid biosynthetic process `http://purl.obolibrary.org/obo/GO_0090153` +#### Removed +- [regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090153) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090153) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ascb_2009" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090153) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0090153" + +- [regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090153) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2009-12-08T03:25:49Z" + +- [regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090153) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of sphingolipid biosynthetic process" + +- [regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090153) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tb" + +- Class: [regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090153) + +- [regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090153) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148)) + +- [regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090153) SubClassOf [regulation of membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_1905038) + +- [regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090153) SubClassOf [regulation of lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046890) + +- [regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090153) SubClassOf [regulation of macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0010556) + +- [regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090153) SubClassOf [regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051171) + +- [regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090153) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) + +- [regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090153) SubClassOf [regulation of cellular component biogenesis](http://purl.obolibrary.org/obo/GO_0044087) + +- [regulation of sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0090153) SubClassOf [regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031326) + + + +### regulation of sulfur metabolic process `http://purl.obolibrary.org/obo/GO_0042762` +#### Removed +- [regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0042762) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0042762" + +- [regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0042762) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0042762) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of sulphur metabolism" + +- [regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0042762) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of sulfur metabolic process" + +- [regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0042762) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of sulphur metabolic process" + +- [regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0042762) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of sulfur metabolism" + +- [regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0042762) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0042762) + +- [regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0042762) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790)) + +- [regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0042762) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) + +- [regulation of sulfur metabolic process](http://purl.obolibrary.org/obo/GO_0042762) SubClassOf [regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031323) + + + +### regulation of superoxide metabolic process `http://purl.obolibrary.org/obo/GO_0090322` +#### Removed +- [regulation of superoxide metabolic process](http://purl.obolibrary.org/obo/GO_0090322) SubClassOf [regulation of reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_2000377) + +#### Added +- [regulation of superoxide metabolic process](http://purl.obolibrary.org/obo/GO_0090322) SubClassOf [regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0019222) + + +### regulation of testosterone biosynthetic process `http://purl.obolibrary.org/obo/GO_2000224` +#### Removed +- [regulation of testosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000224) SubClassOf [regulation of steroid biosynthetic process](http://purl.obolibrary.org/obo/GO_0050810) + +- [regulation of testosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000224) SubClassOf [regulation of ketone biosynthetic process](http://purl.obolibrary.org/obo/GO_0010566) + +#### Added +- [regulation of testosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_2000224) SubClassOf [regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009889) + + +### regulation of testosterone secretion `http://purl.obolibrary.org/obo/GO_2000843` +#### Removed +- [regulation of testosterone secretion](http://purl.obolibrary.org/obo/GO_2000843) SubClassOf [regulation of lipid transport](http://purl.obolibrary.org/obo/GO_0032368) + + + +### regulation of tetrapyrrole biosynthetic process `http://purl.obolibrary.org/obo/GO_1901463` +#### Removed +- [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of tetrapyrrole biosynthetic process" + +- [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of tetrapyrrole biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of tetrapyrrole synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of tetrapyrrole formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-02T14:34:14Z" + +- [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of tetrapyrrole anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901463" + +- Class: [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) + +- [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014)) + +- [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) SubClassOf [regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031326) + +- [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) + +- [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) SubClassOf [regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901401) + + + +### regulation of tetrapyrrole biosynthetic process from glutamate `http://purl.obolibrary.org/obo/GO_1901410` +#### Removed +- [regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901410) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of tetrapyrrole biosynthetic process from glutamate" + +- [regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901410) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901410" + +- [regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901410) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901410) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-01T16:20:56Z" + +- [regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901410) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of tetrapyrrole anabolism from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901410) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of tetrapyrrole formation from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901410) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901410) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of tetrapyrrole biosynthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901410) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of tetrapyrrole synthesis from glutamate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901410) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901410) + +- [regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901410) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526)) + +- [regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901410) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526) + +- [regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901410) SubClassOf [regulation of tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_1901463) + +- [regulation of tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_1901410) SubClassOf [regulation of glutamate metabolic process](http://purl.obolibrary.org/obo/GO_2000211) + + + +### regulation of tetrapyrrole catabolic process `http://purl.obolibrary.org/obo/GO_1901404` +#### Removed +- [regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901404) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901404) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of tetrapyrrole catabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901404) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901404) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901404) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-01T14:38:12Z" + +- [regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901404) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of tetrapyrrole catabolic process" + +- [regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901404) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901404" + +- [regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901404) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of tetrapyrrole degradation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901404) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of tetrapyrrole breakdown" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901404) + +- [regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901404) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015)) + +- [regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901404) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) + +- [regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901404) SubClassOf [regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901401) + +- [regulation of tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_1901404) SubClassOf [regulation of cellular catabolic process](http://purl.obolibrary.org/obo/GO_0031329) + + + +### regulation of tetrapyrrole metabolic process `http://purl.obolibrary.org/obo/GO_1901401` +#### Removed +- [regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901401) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of tetrapyrrole metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901401) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901401) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901401) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901401" + +- [regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901401) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901401) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of tetrapyrrole metabolic process" + +- [regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901401) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-01T14:34:03Z" + +- Class: [regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901401) + +- [regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901401) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013)) + +- [regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901401) SubClassOf [regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031323) + +- [regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901401) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) + +- [regulation of tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_1901401) SubClassOf [regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051171) + + + +### regulation of translation `http://purl.obolibrary.org/obo/GO_0006417` +#### Removed +- [regulation of translation](http://purl.obolibrary.org/obo/GO_0006417) SubClassOf [regulation of cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_2000112) + +- [regulation of translation](http://purl.obolibrary.org/obo/GO_0006417) SubClassOf [regulation of amide metabolic process](http://purl.obolibrary.org/obo/GO_0034248) + +#### Added +- [regulation of translation](http://purl.obolibrary.org/obo/GO_0006417) SubClassOf [regulation of macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0010556) + + +### regulation of translation in response to oxidative stress `http://purl.obolibrary.org/obo/GO_0043556` +#### Removed +- [regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0043556) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0043556) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0043556) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of translation in response to oxidative stress" + +- [regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0043556) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0043556" + +- Class: [regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0043556) + +- [regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0043556) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599)) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [translation](http://purl.obolibrary.org/obo/GO_0006412)) + +- [regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0043556) SubClassOf [negative regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0032055) + +- [regulation of translation in response to oxidative stress](http://purl.obolibrary.org/obo/GO_0043556) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [cellular response to oxidative stress](http://purl.obolibrary.org/obo/GO_0034599) + + + +### regulation of translation in response to stress `http://purl.obolibrary.org/obo/GO_0043555` +#### Removed +- [regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0043555) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0043555) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of translation in response to stress" + +- [regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0043555) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0043555" + +- [regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0043555) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0043555) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "translational stress response" + +- Class: [regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0043555) + +- [regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0043555) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [cellular response to stress](http://purl.obolibrary.org/obo/GO_0033554)) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [translation](http://purl.obolibrary.org/obo/GO_0006412)) + +- [regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0043555) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [cellular response to stress](http://purl.obolibrary.org/obo/GO_0033554) + +- [regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0043555) SubClassOf [regulation of translation](http://purl.obolibrary.org/obo/GO_0006417) + + + +### regulation of translational initiation `http://purl.obolibrary.org/obo/GO_0006446` + +#### Added +- [regulation of translational initiation](http://purl.obolibrary.org/obo/GO_0006446) SubClassOf [regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031323) + + +### regulation of translational initiation in response to stress `http://purl.obolibrary.org/obo/GO_0043558` +#### Removed +- [regulation of translational initiation in response to stress](http://purl.obolibrary.org/obo/GO_0043558) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of translational initiation in response to stress" + +- [regulation of translational initiation in response to stress](http://purl.obolibrary.org/obo/GO_0043558) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [regulation of translational initiation in response to stress](http://purl.obolibrary.org/obo/GO_0043558) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of translation initiation in response to stress" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:hjd" + +- [regulation of translational initiation in response to stress](http://purl.obolibrary.org/obo/GO_0043558) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0043558" + +- [regulation of translational initiation in response to stress](http://purl.obolibrary.org/obo/GO_0043558) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [regulation of translational initiation in response to stress](http://purl.obolibrary.org/obo/GO_0043558) + +- [regulation of translational initiation in response to stress](http://purl.obolibrary.org/obo/GO_0043558) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [cellular response to stress](http://purl.obolibrary.org/obo/GO_0033554)) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [translational initiation](http://purl.obolibrary.org/obo/GO_0006413)) + +- [regulation of translational initiation in response to stress](http://purl.obolibrary.org/obo/GO_0043558) SubClassOf [regulation of translation in response to stress](http://purl.obolibrary.org/obo/GO_0043555) + +- [regulation of translational initiation in response to stress](http://purl.obolibrary.org/obo/GO_0043558) SubClassOf [regulation of translational initiation](http://purl.obolibrary.org/obo/GO_0006446) + + + +### regulation of voltage-gated calcium channel activity `http://purl.obolibrary.org/obo/GO_1901385` +#### Removed +- [regulation of voltage-gated calcium channel activity](http://purl.obolibrary.org/obo/GO_1901385) SubClassOf [regulation of cation channel activity](http://purl.obolibrary.org/obo/GO_2001257) + + + +### related via localization to `http://purl.obolibrary.org/obo/RO_0002337` +#### Removed +- [related via localization to](http://purl.obolibrary.org/obo/RO_0002337) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [related via localization to](http://purl.obolibrary.org/obo/RO_0002337) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### relation between physical entity and a process or stage `http://purl.obolibrary.org/obo/RO_0002487` +#### Removed +- [relation between physical entity and a process or stage](http://purl.obolibrary.org/obo/RO_0002487) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [relation between physical entity and a process or stage](http://purl.obolibrary.org/obo/RO_0002487) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### renal alpha-intercalated cell `http://purl.obolibrary.org/obo/CL_0005011` +#### Removed +- [renal alpha-intercalated cell](http://purl.obolibrary.org/obo/CL_0005011) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### renal sodium ion transport `http://purl.obolibrary.org/obo/GO_0003096` +#### Removed +- [renal sodium ion transport](http://purl.obolibrary.org/obo/GO_0003096) [label](http://www.w3.org/2000/01/rdf-schema#label) "renal sodium ion transport" + +- [renal sodium ion transport](http://purl.obolibrary.org/obo/GO_0003096) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of sodium ions (Na+) by the renal system." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_cardio" + +- [renal sodium ion transport](http://purl.obolibrary.org/obo/GO_0003096) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [renal sodium ion transport](http://purl.obolibrary.org/obo/GO_0003096) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0003096" + +- Class: [renal sodium ion transport](http://purl.obolibrary.org/obo/GO_0003096) + +- [renal sodium ion transport](http://purl.obolibrary.org/obo/GO_0003096) EquivalentTo [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) and ([occurs in](http://purl.obolibrary.org/obo/BFO_0000066) some [renal system](http://purl.obolibrary.org/obo/UBERON_0001008)) + +- [renal sodium ion transport](http://purl.obolibrary.org/obo/GO_0003096) SubClassOf [occurs in](http://purl.obolibrary.org/obo/BFO_0000066) some [renal system](http://purl.obolibrary.org/obo/UBERON_0001008) + +- [renal sodium ion transport](http://purl.obolibrary.org/obo/GO_0003096) SubClassOf [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) + +- [renal sodium ion transport](http://purl.obolibrary.org/obo/GO_0003096) SubClassOf [renal system process](http://purl.obolibrary.org/obo/GO_0003014) + + + +### renal water homeostasis `http://purl.obolibrary.org/obo/GO_0003091` +#### Removed +- [renal water homeostasis](http://purl.obolibrary.org/obo/GO_0003091) EquivalentTo [water homeostasis](http://purl.obolibrary.org/obo/GO_0030104) and ([occurs in](http://purl.obolibrary.org/obo/BFO_0000066) some [renal system](http://purl.obolibrary.org/obo/UBERON_0001008)) + +- [renal water homeostasis](http://purl.obolibrary.org/obo/GO_0003091) SubClassOf [occurs in](http://purl.obolibrary.org/obo/BFO_0000066) some [renal system](http://purl.obolibrary.org/obo/UBERON_0001008) + + + +### reproductive control drug `http://purl.obolibrary.org/obo/CHEBI_50689` +#### Removed +- [reproductive control drug](http://purl.obolibrary.org/obo/CHEBI_50689) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A substance used either in the prevention or facilitation of pregnancy." + +- [reproductive control drug](http://purl.obolibrary.org/obo/CHEBI_50689) [label](http://www.w3.org/2000/01/rdf-schema#label) "reproductive control drug" + +- [reproductive control drug](http://purl.obolibrary.org/obo/CHEBI_50689) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50689" + +- [reproductive control drug](http://purl.obolibrary.org/obo/CHEBI_50689) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [reproductive control drug](http://purl.obolibrary.org/obo/CHEBI_50689) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [reproductive control drug](http://purl.obolibrary.org/obo/CHEBI_50689) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "reproductive control drugs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [reproductive control drug](http://purl.obolibrary.org/obo/CHEBI_50689) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "reproductive control agent" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [reproductive control drug](http://purl.obolibrary.org/obo/CHEBI_50689) + +- [reproductive control drug](http://purl.obolibrary.org/obo/CHEBI_50689) SubClassOf [drug](http://purl.obolibrary.org/obo/CHEBI_23888) + + + +### respiratory ciliated cell `http://purl.obolibrary.org/obo/CL_4030034` +#### Removed +- [respiratory ciliated cell](http://purl.obolibrary.org/obo/CL_4030034) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### response to L-glutamate `http://purl.obolibrary.org/obo/GO_1902065` + +#### Added +- [response to L-glutamate](http://purl.obolibrary.org/obo/GO_1902065) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tb" + +- [response to L-glutamate](http://purl.obolibrary.org/obo/GO_1902065) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2013-04-16T21:21:14Z" + +- [response to L-glutamate](http://purl.obolibrary.org/obo/GO_1902065) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902065" + +- [response to L-glutamate](http://purl.obolibrary.org/obo/GO_1902065) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [response to L-glutamate](http://purl.obolibrary.org/obo/GO_1902065) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23574009" + +- [response to L-glutamate](http://purl.obolibrary.org/obo/GO_1902065) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to L-glutamate" + +- Class: [response to L-glutamate](http://purl.obolibrary.org/obo/GO_1902065) + +- [response to L-glutamate](http://purl.obolibrary.org/obo/GO_1902065) EquivalentTo [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [CHEBI_29985](http://purl.obolibrary.org/obo/CHEBI_29985)) + +- [response to L-glutamate](http://purl.obolibrary.org/obo/GO_1902065) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + +- [response to L-glutamate](http://purl.obolibrary.org/obo/GO_1902065) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [CHEBI_29985](http://purl.obolibrary.org/obo/CHEBI_29985) + + +### response to acetate `http://purl.obolibrary.org/obo/GO_0010034` +#### Removed +- [response to acetate](http://purl.obolibrary.org/obo/GO_0010034) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0010034" + +- [response to acetate](http://purl.obolibrary.org/obo/GO_0010034) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:sm" + +- [response to acetate](http://purl.obolibrary.org/obo/GO_0010034) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to acetate" + +- [response to acetate](http://purl.obolibrary.org/obo/GO_0010034) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [response to acetate](http://purl.obolibrary.org/obo/GO_0010034) + +- [response to acetate](http://purl.obolibrary.org/obo/GO_0010034) EquivalentTo [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089)) + +- [response to acetate](http://purl.obolibrary.org/obo/GO_0010034) SubClassOf [response to organic substance](http://purl.obolibrary.org/obo/GO_0010033) + +- [response to acetate](http://purl.obolibrary.org/obo/GO_0010034) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [acetate](http://purl.obolibrary.org/obo/CHEBI_30089) + +- [response to acetate](http://purl.obolibrary.org/obo/GO_0010034) SubClassOf [response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901700) + + + +### response to acetylcholine `http://purl.obolibrary.org/obo/GO_1905144` +#### Removed +- [response to acetylcholine](http://purl.obolibrary.org/obo/GO_1905144) SubClassOf [response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901698) + +- [response to acetylcholine](http://purl.obolibrary.org/obo/GO_1905144) SubClassOf [response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901700) + +- [response to acetylcholine](http://purl.obolibrary.org/obo/GO_1905144) SubClassOf [response to organic substance](http://purl.obolibrary.org/obo/GO_0010033) + +#### Added +- [response to acetylcholine](http://purl.obolibrary.org/obo/GO_1905144) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to alcohol `http://purl.obolibrary.org/obo/GO_0097305` +#### Removed +- [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0097305" + +- [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24014527" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pr" + +- [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to alcohol" + +- [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-05-15T03:48:45Z" + +- [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "process resulting in tolerance to alcohol" + +- [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "pr" + +- [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:1990335" + +- Class: [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) + +- [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) EquivalentTo [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879)) + +- [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [alcohol](http://purl.obolibrary.org/obo/CHEBI_30879) + +- [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) SubClassOf [response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901700) + +- [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) SubClassOf [response to organic substance](http://purl.obolibrary.org/obo/GO_0010033) + + + +### response to aldosterone `http://purl.obolibrary.org/obo/GO_1904044` +#### Removed +- [response to aldosterone](http://purl.obolibrary.org/obo/GO_1904044) SubClassOf [response to ketone](http://purl.obolibrary.org/obo/GO_1901654) + +- [response to aldosterone](http://purl.obolibrary.org/obo/GO_1904044) SubClassOf [response to mineralocorticoid](http://purl.obolibrary.org/obo/GO_0051385) + +- [response to aldosterone](http://purl.obolibrary.org/obo/GO_1904044) SubClassOf [response to alcohol](http://purl.obolibrary.org/obo/GO_0097305) + +#### Added +- [response to aldosterone](http://purl.obolibrary.org/obo/GO_1904044) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to alkaloid `http://purl.obolibrary.org/obo/GO_0043279` +#### Removed +- [response to alkaloid](http://purl.obolibrary.org/obo/GO_0043279) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0043279" + +- [response to alkaloid](http://purl.obolibrary.org/obo/GO_0043279) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [response to alkaloid](http://purl.obolibrary.org/obo/GO_0043279) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [response to alkaloid](http://purl.obolibrary.org/obo/GO_0043279) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to alkaloid" + +- Class: [response to alkaloid](http://purl.obolibrary.org/obo/GO_0043279) + +- [response to alkaloid](http://purl.obolibrary.org/obo/GO_0043279) EquivalentTo [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315)) + +- [response to alkaloid](http://purl.obolibrary.org/obo/GO_0043279) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [alkaloid](http://purl.obolibrary.org/obo/CHEBI_22315) + +- [response to alkaloid](http://purl.obolibrary.org/obo/GO_0043279) SubClassOf [response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0010243) + + + +### response to alkane `http://purl.obolibrary.org/obo/GO_1902778` +#### Removed +- [response to alkane](http://purl.obolibrary.org/obo/GO_1902778) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [response to alkane](http://purl.obolibrary.org/obo/GO_1902778) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902778" + +- [response to alkane](http://purl.obolibrary.org/obo/GO_1902778) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "process resulting in tolerance to alkane" + +- [response to alkane](http://purl.obolibrary.org/obo/GO_1902778) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:1990373" + +- [response to alkane](http://purl.obolibrary.org/obo/GO_1902778) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to alkane" + +- [response to alkane](http://purl.obolibrary.org/obo/GO_1902778) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22958739" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23826995" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000071" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- Class: [response to alkane](http://purl.obolibrary.org/obo/GO_1902778) + +- [response to alkane](http://purl.obolibrary.org/obo/GO_1902778) EquivalentTo [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [alkane](http://purl.obolibrary.org/obo/CHEBI_18310)) + +- [response to alkane](http://purl.obolibrary.org/obo/GO_1902778) SubClassOf [response to organic substance](http://purl.obolibrary.org/obo/GO_0010033) + +- [response to alkane](http://purl.obolibrary.org/obo/GO_1902778) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [alkane](http://purl.obolibrary.org/obo/CHEBI_18310) + + + +### response to amine `http://purl.obolibrary.org/obo/GO_0014075` +#### Removed +- [response to amine](http://purl.obolibrary.org/obo/GO_0014075) SubClassOf [response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0010243) + +#### Added +- [response to amine](http://purl.obolibrary.org/obo/GO_0014075) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to amino acid `http://purl.obolibrary.org/obo/GO_0043200` +#### Removed +- [response to amino acid](http://purl.obolibrary.org/obo/GO_0043200) SubClassOf [response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0010243) + +- [response to amino acid](http://purl.obolibrary.org/obo/GO_0043200) SubClassOf [response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901700) + + + +### response to ammonium ion `http://purl.obolibrary.org/obo/GO_0060359` +#### Removed +- [response to ammonium ion](http://purl.obolibrary.org/obo/GO_0060359) SubClassOf [response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901698) + +- [response to ammonium ion](http://purl.obolibrary.org/obo/GO_0060359) SubClassOf [response to inorganic substance](http://purl.obolibrary.org/obo/GO_0010035) + +#### Added +- [response to ammonium ion](http://purl.obolibrary.org/obo/GO_0060359) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to bile acid `http://purl.obolibrary.org/obo/GO_1903412` +#### Removed +- [response to bile acid](http://purl.obolibrary.org/obo/GO_1903412) SubClassOf [response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901700) + +- [response to bile acid](http://purl.obolibrary.org/obo/GO_1903412) SubClassOf [response to lipid](http://purl.obolibrary.org/obo/GO_0033993) + +- [response to bile acid](http://purl.obolibrary.org/obo/GO_1903412) SubClassOf [response to organic cyclic compound](http://purl.obolibrary.org/obo/GO_0014070) + +#### Added +- [response to bile acid](http://purl.obolibrary.org/obo/GO_1903412) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to butyrate `http://purl.obolibrary.org/obo/GO_1903544` +#### Removed +- [response to butyrate](http://purl.obolibrary.org/obo/GO_1903544) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mr" + +- [response to butyrate](http://purl.obolibrary.org/obo/GO_1903544) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-10-17T13:57:25Z" + +- [response to butyrate](http://purl.obolibrary.org/obo/GO_1903544) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to butyrate" + +- [response to butyrate](http://purl.obolibrary.org/obo/GO_1903544) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1903544" + +- [response to butyrate](http://purl.obolibrary.org/obo/GO_1903544) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mr" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9734870" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000071" + +- [response to butyrate](http://purl.obolibrary.org/obo/GO_1903544) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [response to butyrate](http://purl.obolibrary.org/obo/GO_1903544) + +- [response to butyrate](http://purl.obolibrary.org/obo/GO_1903544) EquivalentTo [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968)) + +- [response to butyrate](http://purl.obolibrary.org/obo/GO_1903544) SubClassOf [response to fatty acid](http://purl.obolibrary.org/obo/GO_0070542) + +- [response to butyrate](http://purl.obolibrary.org/obo/GO_1903544) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [butyrate](http://purl.obolibrary.org/obo/CHEBI_17968) + + + +### response to calcium ion `http://purl.obolibrary.org/obo/GO_0051592` +#### Removed +- [response to calcium ion](http://purl.obolibrary.org/obo/GO_0051592) SubClassOf [response to metal ion](http://purl.obolibrary.org/obo/GO_0010038) + +#### Added +- [response to calcium ion](http://purl.obolibrary.org/obo/GO_0051592) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to carbamate `http://purl.obolibrary.org/obo/GO_0046681` +#### Removed +- [response to carbamate](http://purl.obolibrary.org/obo/GO_0046681) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbamate susceptibility/resistance" + +- [response to carbamate](http://purl.obolibrary.org/obo/GO_0046681) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to carbamate" + +- [response to carbamate](http://purl.obolibrary.org/obo/GO_0046681) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [response to carbamate](http://purl.obolibrary.org/obo/GO_0046681) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "carbamate resistance" + +- [response to carbamate](http://purl.obolibrary.org/obo/GO_0046681) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046681" + +- [response to carbamate](http://purl.obolibrary.org/obo/GO_0046681) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0721662544" + +- Class: [response to carbamate](http://purl.obolibrary.org/obo/GO_0046681) + +- [response to carbamate](http://purl.obolibrary.org/obo/GO_0046681) EquivalentTo [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941)) + +- [response to carbamate](http://purl.obolibrary.org/obo/GO_0046681) SubClassOf [response to insecticide](http://purl.obolibrary.org/obo/GO_0017085) + +- [response to carbamate](http://purl.obolibrary.org/obo/GO_0046681) SubClassOf [response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901700) + +- [response to carbamate](http://purl.obolibrary.org/obo/GO_0046681) SubClassOf [response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0010243) + +- [response to carbamate](http://purl.obolibrary.org/obo/GO_0046681) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [carbamate](http://purl.obolibrary.org/obo/CHEBI_13941) + + + +### response to carbohydrate `http://purl.obolibrary.org/obo/GO_0009743` +#### Removed +- [response to carbohydrate](http://purl.obolibrary.org/obo/GO_0009743) SubClassOf [response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901700) + +- [response to carbohydrate](http://purl.obolibrary.org/obo/GO_0009743) SubClassOf [response to organic substance](http://purl.obolibrary.org/obo/GO_0010033) + +#### Added +- [response to carbohydrate](http://purl.obolibrary.org/obo/GO_0009743) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to catecholamine `http://purl.obolibrary.org/obo/GO_0071869` +#### Removed +- [response to catecholamine](http://purl.obolibrary.org/obo/GO_0071869) SubClassOf [response to monoamine](http://purl.obolibrary.org/obo/GO_0071867) + +- [response to catecholamine](http://purl.obolibrary.org/obo/GO_0071869) SubClassOf [response to organic cyclic compound](http://purl.obolibrary.org/obo/GO_0014070) + +- [response to catecholamine](http://purl.obolibrary.org/obo/GO_0071869) SubClassOf [response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901700) + +#### Added +- [response to catecholamine](http://purl.obolibrary.org/obo/GO_0071869) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to corticosteroid `http://purl.obolibrary.org/obo/GO_0031960` +#### Removed +- [response to corticosteroid](http://purl.obolibrary.org/obo/GO_0031960) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to corticosteroid" + +- [response to corticosteroid](http://purl.obolibrary.org/obo/GO_0031960) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [response to corticosteroid](http://purl.obolibrary.org/obo/GO_0031960) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "response to corticosteroid stimulus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dos" + +- [response to corticosteroid](http://purl.obolibrary.org/obo/GO_0031960) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0031960" + +- [response to corticosteroid](http://purl.obolibrary.org/obo/GO_0031960) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11027914" + +- Class: [response to corticosteroid](http://purl.obolibrary.org/obo/GO_0031960) + +- [response to corticosteroid](http://purl.obolibrary.org/obo/GO_0031960) EquivalentTo [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [corticosteroid](http://purl.obolibrary.org/obo/CHEBI_50858)) + +- [response to corticosteroid](http://purl.obolibrary.org/obo/GO_0031960) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [corticosteroid](http://purl.obolibrary.org/obo/CHEBI_50858) + +- [response to corticosteroid](http://purl.obolibrary.org/obo/GO_0031960) SubClassOf [response to steroid hormone](http://purl.obolibrary.org/obo/GO_0048545) + + + +### response to dopamine `http://purl.obolibrary.org/obo/GO_1903350` +#### Removed +- [response to dopamine](http://purl.obolibrary.org/obo/GO_1903350) SubClassOf [response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901698) + +#### Added +- [response to dopamine](http://purl.obolibrary.org/obo/GO_1903350) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to epinephrine `http://purl.obolibrary.org/obo/GO_0071871` +#### Removed +- [response to epinephrine](http://purl.obolibrary.org/obo/GO_0071871) SubClassOf [response to catecholamine](http://purl.obolibrary.org/obo/GO_0071869) + +#### Added +- [response to epinephrine](http://purl.obolibrary.org/obo/GO_0071871) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to estradiol `http://purl.obolibrary.org/obo/GO_0032355` +#### Removed +- [response to estradiol](http://purl.obolibrary.org/obo/GO_0032355) SubClassOf [response to organic cyclic compound](http://purl.obolibrary.org/obo/GO_0014070) + +- [response to estradiol](http://purl.obolibrary.org/obo/GO_0032355) SubClassOf [response to lipid](http://purl.obolibrary.org/obo/GO_0033993) + +- [response to estradiol](http://purl.obolibrary.org/obo/GO_0032355) SubClassOf [response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901700) + +#### Added +- [response to estradiol](http://purl.obolibrary.org/obo/GO_0032355) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to fatty acid `http://purl.obolibrary.org/obo/GO_0070542` +#### Removed +- [response to fatty acid](http://purl.obolibrary.org/obo/GO_0070542) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:lp" + +- [response to fatty acid](http://purl.obolibrary.org/obo/GO_0070542) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [response to fatty acid](http://purl.obolibrary.org/obo/GO_0070542) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0070542" + +- [response to fatty acid](http://purl.obolibrary.org/obo/GO_0070542) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to fatty acid" + +- Class: [response to fatty acid](http://purl.obolibrary.org/obo/GO_0070542) + +- [response to fatty acid](http://purl.obolibrary.org/obo/GO_0070542) EquivalentTo [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868)) + +- [response to fatty acid](http://purl.obolibrary.org/obo/GO_0070542) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) + +- [response to fatty acid](http://purl.obolibrary.org/obo/GO_0070542) SubClassOf [response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901700) + +- [response to fatty acid](http://purl.obolibrary.org/obo/GO_0070542) SubClassOf [response to lipid](http://purl.obolibrary.org/obo/GO_0033993) + + + +### response to formic acid `http://purl.obolibrary.org/obo/GO_1901425` +#### Removed +- [response to formic acid](http://purl.obolibrary.org/obo/GO_1901425) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [response to formic acid](http://purl.obolibrary.org/obo/GO_1901425) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formic acid stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mengo_curators" + +- [response to formic acid](http://purl.obolibrary.org/obo/GO_1901425) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901425" + +- [response to formic acid](http://purl.obolibrary.org/obo/GO_1901425) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "tt" + +- [response to formic acid](http://purl.obolibrary.org/obo/GO_1901425) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to formic acid" + +- [response to formic acid](http://purl.obolibrary.org/obo/GO_1901425) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-10-01T18:43:05Z" + +- Class: [response to formic acid](http://purl.obolibrary.org/obo/GO_1901425) + +- [response to formic acid](http://purl.obolibrary.org/obo/GO_1901425) EquivalentTo [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [formate](http://purl.obolibrary.org/obo/CHEBI_15740)) + +- [response to formic acid](http://purl.obolibrary.org/obo/GO_1901425) SubClassOf [response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901700) + +- [response to formic acid](http://purl.obolibrary.org/obo/GO_1901425) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [formate](http://purl.obolibrary.org/obo/CHEBI_15740) + +- [response to formic acid](http://purl.obolibrary.org/obo/GO_1901425) SubClassOf [response to organic substance](http://purl.obolibrary.org/obo/GO_0010033) + + + +### response to glucagon `http://purl.obolibrary.org/obo/GO_0033762` +#### Removed +- [response to glucagon](http://purl.obolibrary.org/obo/GO_0033762) SubClassOf [response to peptide hormone](http://purl.obolibrary.org/obo/GO_0043434) + +#### Added +- [response to glucagon](http://purl.obolibrary.org/obo/GO_0033762) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to glucocorticoid `http://purl.obolibrary.org/obo/GO_0051384` +#### Removed +- [response to glucocorticoid](http://purl.obolibrary.org/obo/GO_0051384) SubClassOf [response to corticosteroid](http://purl.obolibrary.org/obo/GO_0031960) + +#### Added +- [response to glucocorticoid](http://purl.obolibrary.org/obo/GO_0051384) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to glucose `http://purl.obolibrary.org/obo/GO_0009749` +#### Removed +- [response to glucose](http://purl.obolibrary.org/obo/GO_0009749) SubClassOf [response to hexose](http://purl.obolibrary.org/obo/GO_0009746) + +#### Added +- [response to glucose](http://purl.obolibrary.org/obo/GO_0009749) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to glycine `http://purl.obolibrary.org/obo/GO_1905429` +#### Removed +- [response to glycine](http://purl.obolibrary.org/obo/GO_1905429) SubClassOf [response to organic substance](http://purl.obolibrary.org/obo/GO_0010033) + +#### Added +- [response to glycine](http://purl.obolibrary.org/obo/GO_1905429) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to glycoprotein `http://purl.obolibrary.org/obo/GO_1904587` +#### Removed +- [response to glycoprotein](http://purl.obolibrary.org/obo/GO_1904587) SubClassOf [response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901700) + +- [response to glycoprotein](http://purl.obolibrary.org/obo/GO_1904587) SubClassOf [response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0010243) + +#### Added +- [response to glycoprotein](http://purl.obolibrary.org/obo/GO_1904587) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to hexose `http://purl.obolibrary.org/obo/GO_0009746` +#### Removed +- [response to hexose](http://purl.obolibrary.org/obo/GO_0009746) SubClassOf [response to monosaccharide](http://purl.obolibrary.org/obo/GO_0034284) + +#### Added +- [response to hexose](http://purl.obolibrary.org/obo/GO_0009746) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to histamine `http://purl.obolibrary.org/obo/GO_0034776` +#### Removed +- [response to histamine](http://purl.obolibrary.org/obo/GO_0034776) SubClassOf [response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901698) + +#### Added +- [response to histamine](http://purl.obolibrary.org/obo/GO_0034776) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to insecticide `http://purl.obolibrary.org/obo/GO_0017085` +#### Removed +- [response to insecticide](http://purl.obolibrary.org/obo/GO_0017085) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:curators" + +- [response to insecticide](http://purl.obolibrary.org/obo/GO_0017085) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0017085" + +- [response to insecticide](http://purl.obolibrary.org/obo/GO_0017085) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "insecticide resistance" + +- [response to insecticide](http://purl.obolibrary.org/obo/GO_0017085) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to insecticide" + +- [response to insecticide](http://purl.obolibrary.org/obo/GO_0017085) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [response to insecticide](http://purl.obolibrary.org/obo/GO_0017085) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "insecticide susceptibility/resistance" + +- Class: [response to insecticide](http://purl.obolibrary.org/obo/GO_0017085) + +- [response to insecticide](http://purl.obolibrary.org/obo/GO_0017085) SubClassOf [response to toxic substance](http://purl.obolibrary.org/obo/GO_0009636) + + + +### response to iron ion `http://purl.obolibrary.org/obo/GO_0010039` +#### Removed +- [response to iron ion](http://purl.obolibrary.org/obo/GO_0010039) SubClassOf [response to metal ion](http://purl.obolibrary.org/obo/GO_0010038) + +#### Added +- [response to iron ion](http://purl.obolibrary.org/obo/GO_0010039) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to ketone `http://purl.obolibrary.org/obo/GO_1901654` +#### Removed +- [response to ketone](http://purl.obolibrary.org/obo/GO_1901654) SubClassOf [response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901700) + + + +### response to lipid `http://purl.obolibrary.org/obo/GO_0033993` +#### Removed +- [response to lipid](http://purl.obolibrary.org/obo/GO_0033993) SubClassOf [response to organic substance](http://purl.obolibrary.org/obo/GO_0010033) + +#### Added +- [response to lipid](http://purl.obolibrary.org/obo/GO_0033993) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to lipoprotein particle `http://purl.obolibrary.org/obo/GO_0055094` +#### Removed +- [response to lipoprotein particle](http://purl.obolibrary.org/obo/GO_0055094) SubClassOf [response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0010243) + + + +### response to metal ion `http://purl.obolibrary.org/obo/GO_0010038` +#### Removed +- [response to metal ion](http://purl.obolibrary.org/obo/GO_0010038) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to metal ion" + +- [response to metal ion](http://purl.obolibrary.org/obo/GO_0010038) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:sm" + +- [response to metal ion](http://purl.obolibrary.org/obo/GO_0010038) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [response to metal ion](http://purl.obolibrary.org/obo/GO_0010038) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0010038" + +- [response to metal ion](http://purl.obolibrary.org/obo/GO_0010038) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "response to heavy metal" + +- [response to metal ion](http://purl.obolibrary.org/obo/GO_0010038) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "heavy metal sensitivity/resistance" + +- [response to metal ion](http://purl.obolibrary.org/obo/GO_0010038) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "response to metal" + +- Class: [response to metal ion](http://purl.obolibrary.org/obo/GO_0010038) + +- [response to metal ion](http://purl.obolibrary.org/obo/GO_0010038) EquivalentTo [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213)) + +- [response to metal ion](http://purl.obolibrary.org/obo/GO_0010038) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) + +- [response to metal ion](http://purl.obolibrary.org/obo/GO_0010038) SubClassOf [response to inorganic substance](http://purl.obolibrary.org/obo/GO_0010035) + + + +### response to mineralocorticoid `http://purl.obolibrary.org/obo/GO_0051385` +#### Removed +- [response to mineralocorticoid](http://purl.obolibrary.org/obo/GO_0051385) SubClassOf [response to corticosteroid](http://purl.obolibrary.org/obo/GO_0031960) + +#### Added +- [response to mineralocorticoid](http://purl.obolibrary.org/obo/GO_0051385) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to monoamine `http://purl.obolibrary.org/obo/GO_0071867` +#### Removed +- [response to monoamine](http://purl.obolibrary.org/obo/GO_0071867) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "response to monoamine stimulus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dos" + +- [response to monoamine](http://purl.obolibrary.org/obo/GO_0071867) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-09-13T02:36:37Z" + +- [response to monoamine](http://purl.obolibrary.org/obo/GO_0071867) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [response to monoamine](http://purl.obolibrary.org/obo/GO_0071867) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- [response to monoamine](http://purl.obolibrary.org/obo/GO_0071867) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to monoamine" + +- [response to monoamine](http://purl.obolibrary.org/obo/GO_0071867) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0071867" + +- [response to monoamine](http://purl.obolibrary.org/obo/GO_0071867) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- Class: [response to monoamine](http://purl.obolibrary.org/obo/GO_0071867) + +- [response to monoamine](http://purl.obolibrary.org/obo/GO_0071867) EquivalentTo [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534)) + +- [response to monoamine](http://purl.obolibrary.org/obo/GO_0071867) SubClassOf [response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0010243) + +- [response to monoamine](http://purl.obolibrary.org/obo/GO_0071867) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [monoamine](http://purl.obolibrary.org/obo/CHEBI_63534) + + + +### response to monosaccharide `http://purl.obolibrary.org/obo/GO_0034284` +#### Removed +- [response to monosaccharide](http://purl.obolibrary.org/obo/GO_0034284) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to monosaccharide" + +- [response to monosaccharide](http://purl.obolibrary.org/obo/GO_0034284) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "response to monosaccharide stimulus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dos" + +- [response to monosaccharide](http://purl.obolibrary.org/obo/GO_0034284) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0034284" + +- [response to monosaccharide](http://purl.obolibrary.org/obo/GO_0034284) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [response to monosaccharide](http://purl.obolibrary.org/obo/GO_0034284) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [response to monosaccharide](http://purl.obolibrary.org/obo/GO_0034284) + +- [response to monosaccharide](http://purl.obolibrary.org/obo/GO_0034284) EquivalentTo [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381)) + +- [response to monosaccharide](http://purl.obolibrary.org/obo/GO_0034284) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [monosaccharide](http://purl.obolibrary.org/obo/CHEBI_35381) + +- [response to monosaccharide](http://purl.obolibrary.org/obo/GO_0034284) SubClassOf [response to carbohydrate](http://purl.obolibrary.org/obo/GO_0009743) + + + +### response to nitric oxide `http://purl.obolibrary.org/obo/GO_0071731` +#### Removed +- [response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071731) SubClassOf [response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901698) + +- [response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071731) SubClassOf [response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901700) + +- [response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071731) SubClassOf [response to inorganic substance](http://purl.obolibrary.org/obo/GO_0010035) + +#### Added +- [response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071731) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to nitrogen compound `http://purl.obolibrary.org/obo/GO_1901698` +#### Removed +- [response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901698) SubClassOf [response to chemical](http://purl.obolibrary.org/obo/GO_0042221) + +#### Added +- [response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901698) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to norepinephrine `http://purl.obolibrary.org/obo/GO_0071873` +#### Removed +- [response to norepinephrine](http://purl.obolibrary.org/obo/GO_0071873) SubClassOf [response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901698) + +- [response to norepinephrine](http://purl.obolibrary.org/obo/GO_0071873) SubClassOf [response to organic substance](http://purl.obolibrary.org/obo/GO_0010033) + +#### Added +- [response to norepinephrine](http://purl.obolibrary.org/obo/GO_0071873) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to organic cyclic compound `http://purl.obolibrary.org/obo/GO_0014070` +#### Removed +- [response to organic cyclic compound](http://purl.obolibrary.org/obo/GO_0014070) SubClassOf [response to organic substance](http://purl.obolibrary.org/obo/GO_0010033) + +#### Added +- [response to organic cyclic compound](http://purl.obolibrary.org/obo/GO_0014070) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to organonitrogen compound `http://purl.obolibrary.org/obo/GO_0010243` +#### Removed +- [response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0010243) SubClassOf [response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901698) + +- [response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0010243) SubClassOf [response to organic substance](http://purl.obolibrary.org/obo/GO_0010033) + +#### Added +- [response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0010243) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to oxidative stress `http://purl.obolibrary.org/obo/GO_0006979` +#### Removed +- [response to oxidative stress](http://purl.obolibrary.org/obo/GO_0006979) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [response to oxidative stress](http://purl.obolibrary.org/obo/GO_0006979) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to oxidative stress" + +- [response to oxidative stress](http://purl.obolibrary.org/obo/GO_0006979) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006979" + +- [response to oxidative stress](http://purl.obolibrary.org/obo/GO_0006979) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12115731" + +- [response to oxidative stress](http://purl.obolibrary.org/obo/GO_0006979) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_yeast](http://purl.obolibrary.org/obo/go#goslim_yeast) + +- Class: [response to oxidative stress](http://purl.obolibrary.org/obo/GO_0006979) + +- [response to oxidative stress](http://purl.obolibrary.org/obo/GO_0006979) SubClassOf [response to stress](http://purl.obolibrary.org/obo/GO_0006950) + + + +### response to oxygen radical `http://purl.obolibrary.org/obo/GO_0000305` +#### Removed +- [response to oxygen radical](http://purl.obolibrary.org/obo/GO_0000305) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0000305" + +- [response to oxygen radical](http://purl.obolibrary.org/obo/GO_0000305) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [response to oxygen radical](http://purl.obolibrary.org/obo/GO_0000305) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to oxygen radical" + +- [response to oxygen radical](http://purl.obolibrary.org/obo/GO_0000305) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0124325653" + +- Class: [response to oxygen radical](http://purl.obolibrary.org/obo/GO_0000305) + +- [response to oxygen radical](http://purl.obolibrary.org/obo/GO_0000305) EquivalentTo [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [oxygen radical](http://purl.obolibrary.org/obo/CHEBI_61073)) + +- [response to oxygen radical](http://purl.obolibrary.org/obo/GO_0000305) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [oxygen radical](http://purl.obolibrary.org/obo/CHEBI_61073) + +- [response to oxygen radical](http://purl.obolibrary.org/obo/GO_0000305) SubClassOf [response to inorganic substance](http://purl.obolibrary.org/obo/GO_0010035) + +- [response to oxygen radical](http://purl.obolibrary.org/obo/GO_0000305) SubClassOf [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) + + + +### response to peptide `http://purl.obolibrary.org/obo/GO_1901652` +#### Removed +- [response to peptide](http://purl.obolibrary.org/obo/GO_1901652) SubClassOf [response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901700) + +- [response to peptide](http://purl.obolibrary.org/obo/GO_1901652) SubClassOf [response to organonitrogen compound](http://purl.obolibrary.org/obo/GO_0010243) + +#### Added +- [response to peptide](http://purl.obolibrary.org/obo/GO_1901652) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to peptide hormone `http://purl.obolibrary.org/obo/GO_0043434` +#### Removed +- [response to peptide hormone](http://purl.obolibrary.org/obo/GO_0043434) SubClassOf [response to peptide](http://purl.obolibrary.org/obo/GO_1901652) + + + +### response to progesterone `http://purl.obolibrary.org/obo/GO_0032570` +#### Removed +- [response to progesterone](http://purl.obolibrary.org/obo/GO_0032570) SubClassOf [response to steroid hormone](http://purl.obolibrary.org/obo/GO_0048545) + +- [response to progesterone](http://purl.obolibrary.org/obo/GO_0032570) SubClassOf [response to ketone](http://purl.obolibrary.org/obo/GO_1901654) + +#### Added +- [response to progesterone](http://purl.obolibrary.org/obo/GO_0032570) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to reactive oxygen species `http://purl.obolibrary.org/obo/GO_0000302` +#### Removed +- [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "response to reactive oxygen intermediate" + +- [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0000302" + +- [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "response to ROS" + +- [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "response to ROI" + +- [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "response to active oxygen species" + +- [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" + +- [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to reactive oxygen species" + +- [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "response to reactive oxidative species" + +- [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "response to AOS" + +- [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) + +- [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) EquivalentTo [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [reactive oxygen species](http://purl.obolibrary.org/obo/CHEBI_26523)) + +- [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) SubClassOf [response to oxygen-containing compound](http://purl.obolibrary.org/obo/GO_1901700) + +- [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) SubClassOf [response to oxidative stress](http://purl.obolibrary.org/obo/GO_0006979) + +- [response to reactive oxygen species](http://purl.obolibrary.org/obo/GO_0000302) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [reactive oxygen species](http://purl.obolibrary.org/obo/CHEBI_26523) + + + +### response to salt `http://purl.obolibrary.org/obo/GO_1902074` +#### Removed +- [response to salt](http://purl.obolibrary.org/obo/GO_1902074) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mls" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16666921" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [response to salt](http://purl.obolibrary.org/obo/GO_1902074) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [response to salt](http://purl.obolibrary.org/obo/GO_1902074) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2013-04-22T15:41:57Z" + +- [response to salt](http://purl.obolibrary.org/obo/GO_1902074) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "response to salinity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mls" + +- [response to salt](http://purl.obolibrary.org/obo/GO_1902074) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902074" + +- [response to salt](http://purl.obolibrary.org/obo/GO_1902074) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to salt" + +- [response to salt](http://purl.obolibrary.org/obo/GO_1902074) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mls" + +- Class: [response to salt](http://purl.obolibrary.org/obo/GO_1902074) + +- [response to salt](http://purl.obolibrary.org/obo/GO_1902074) EquivalentTo [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [salt](http://purl.obolibrary.org/obo/CHEBI_24866)) + +- [response to salt](http://purl.obolibrary.org/obo/GO_1902074) SubClassOf [response to chemical](http://purl.obolibrary.org/obo/GO_0042221) + +- [response to salt](http://purl.obolibrary.org/obo/GO_1902074) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [salt](http://purl.obolibrary.org/obo/CHEBI_24866) + + + +### response to serotonin `http://purl.obolibrary.org/obo/GO_1904014` +#### Removed +- [response to serotonin](http://purl.obolibrary.org/obo/GO_1904014) SubClassOf [response to nitrogen compound](http://purl.obolibrary.org/obo/GO_1901698) + +#### Added +- [response to serotonin](http://purl.obolibrary.org/obo/GO_1904014) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to steroid hormone `http://purl.obolibrary.org/obo/GO_0048545` +#### Removed +- [response to steroid hormone](http://purl.obolibrary.org/obo/GO_0048545) SubClassOf [response to organic cyclic compound](http://purl.obolibrary.org/obo/GO_0014070) + +- [response to steroid hormone](http://purl.obolibrary.org/obo/GO_0048545) SubClassOf [response to lipid](http://purl.obolibrary.org/obo/GO_0033993) + + + +### response to superoxide `http://purl.obolibrary.org/obo/GO_0000303` +#### Removed +- [response to superoxide](http://purl.obolibrary.org/obo/GO_0000303) SubClassOf [response to oxygen radical](http://purl.obolibrary.org/obo/GO_0000305) + +#### Added +- [response to superoxide](http://purl.obolibrary.org/obo/GO_0000303) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to testosterone `http://purl.obolibrary.org/obo/GO_0033574` +#### Removed +- [response to testosterone](http://purl.obolibrary.org/obo/GO_0033574) SubClassOf [response to organic cyclic compound](http://purl.obolibrary.org/obo/GO_0014070) + +- [response to testosterone](http://purl.obolibrary.org/obo/GO_0033574) SubClassOf [response to lipid](http://purl.obolibrary.org/obo/GO_0033993) + +- [response to testosterone](http://purl.obolibrary.org/obo/GO_0033574) SubClassOf [response to ketone](http://purl.obolibrary.org/obo/GO_1901654) + +#### Added +- [response to testosterone](http://purl.obolibrary.org/obo/GO_0033574) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### response to vasopressin `http://purl.obolibrary.org/obo/GO_1904116` +#### Removed +- [response to vasopressin](http://purl.obolibrary.org/obo/GO_1904116) SubClassOf [response to peptide hormone](http://purl.obolibrary.org/obo/GO_0043434) + +#### Added +- [response to vasopressin](http://purl.obolibrary.org/obo/GO_1904116) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + +### results in acquisition of features of `http://purl.obolibrary.org/obo/RO_0002315` +#### Removed +- [results in acquisition of features of](http://purl.obolibrary.org/obo/RO_0002315) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [results in acquisition of features of](http://purl.obolibrary.org/obo/RO_0002315) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### results in changes to anatomical or cellular structure `http://purl.obolibrary.org/obo/RO_0040036` +#### Removed +- [results in changes to anatomical or cellular structure](http://purl.obolibrary.org/obo/RO_0040036) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "cjm" + +#### Added +- [results in changes to anatomical or cellular structure](http://purl.obolibrary.org/obo/RO_0040036) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### results in development of `http://purl.obolibrary.org/obo/RO_0002296` +#### Removed +- [results in development of](http://purl.obolibrary.org/obo/RO_0002296) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [results in development of](http://purl.obolibrary.org/obo/RO_0002296) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### results in developmental progression of `http://purl.obolibrary.org/obo/RO_0002295` +#### Removed +- [results in developmental progression of](http://purl.obolibrary.org/obo/RO_0002295) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [results in developmental progression of](http://purl.obolibrary.org/obo/RO_0002295) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### results in formation of `http://purl.obolibrary.org/obo/RO_0002297` +#### Removed +- [results in formation of](http://purl.obolibrary.org/obo/RO_0002297) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [results in formation of](http://purl.obolibrary.org/obo/RO_0002297) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### results in growth of `http://purl.obolibrary.org/obo/RO_0002343` +#### Removed +- [results in growth of](http://purl.obolibrary.org/obo/RO_0002343) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [results in growth of](http://purl.obolibrary.org/obo/RO_0002343) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### results in maturation of `http://purl.obolibrary.org/obo/RO_0002299` +#### Removed +- [results in maturation of](http://purl.obolibrary.org/obo/RO_0002299) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [results in maturation of](http://purl.obolibrary.org/obo/RO_0002299) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### results in morphogenesis of `http://purl.obolibrary.org/obo/RO_0002298` +#### Removed +- [results in morphogenesis of](http://purl.obolibrary.org/obo/RO_0002298) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [results in morphogenesis of](http://purl.obolibrary.org/obo/RO_0002298) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### results in movement of `http://purl.obolibrary.org/obo/RO_0002565` +#### Removed +- [results in movement of](http://purl.obolibrary.org/obo/RO_0002565) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [results in movement of](http://purl.obolibrary.org/obo/RO_0002565) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### results in transport across `http://purl.obolibrary.org/obo/RO_0002342` +#### Removed +- [results in transport across](http://purl.obolibrary.org/obo/RO_0002342) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [results in transport across](http://purl.obolibrary.org/obo/RO_0002342) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### results in transport along `http://purl.obolibrary.org/obo/RO_0002341` +#### Removed +- [results in transport along](http://purl.obolibrary.org/obo/RO_0002341) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [results in transport along](http://purl.obolibrary.org/obo/RO_0002341) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### results in transport to from or in `http://purl.obolibrary.org/obo/RO_0002344` +#### Removed +- [results in transport to from or in](http://purl.obolibrary.org/obo/RO_0002344) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [results in transport to from or in](http://purl.obolibrary.org/obo/RO_0002344) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### reticulocyte `http://purl.obolibrary.org/obo/CL_0000558` +#### Removed +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) EquivalentTo [erythroid lineage cell](http://purl.obolibrary.org/obo/CL_0000764) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [extracellular exosome assembly](http://purl.obolibrary.org/obo/GO_0071971)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +#### Added +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) EquivalentTo [erythroid lineage cell](http://purl.obolibrary.org/obo/CL_0000764) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [extracellular exosome assembly](http://purl.obolibrary.org/obo/GO_0071971)) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289) + +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084) + + +### retinal astrocyte `http://purl.obolibrary.org/obo/CL_4033015` + +#### Added +- [retinal astrocyte](http://purl.obolibrary.org/obo/CL_4033015) [date](http://purl.org/dc/terms/date) "2023-03-02T14:38:32Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [retinal astrocyte](http://purl.obolibrary.org/obo/CL_4033015) [label](http://www.w3.org/2000/01/rdf-schema#label) "retinal astrocyte" + +- [retinal astrocyte](http://purl.obolibrary.org/obo/CL_4033015) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A star-shaped glial cell that is part of some retina. This cell links neurons to blood vessels and may provide structural and physiological support to optic nerve head axons." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25236977" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:33796062" + +- [retinal astrocyte](http://purl.obolibrary.org/obo/CL_4033015) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "retinal astroglia" + - [synonym_type_property](http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty) [plural term](http://purl.obolibrary.org/obo/uberon/core#PLURAL) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:33796062" + +- [retinal astrocyte](http://purl.obolibrary.org/obo/CL_4033015) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "In response to elevated intraocular pressure, a retinal astrocyte may modulate extracellular matrix remodeling. In the human retina, a retinal astrocyte is GFAP-positive, SOD3-positive and GYPC-positive." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32555229" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:33796062" + +- [retinal astrocyte](http://purl.obolibrary.org/obo/CL_4033015) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- Class: [retinal astrocyte](http://purl.obolibrary.org/obo/CL_4033015) + +- [retinal astrocyte](http://purl.obolibrary.org/obo/CL_4033015) EquivalentTo [astrocyte](http://purl.obolibrary.org/obo/CL_0000127) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [retina](http://purl.obolibrary.org/obo/UBERON_0000966)) + +- [retinal astrocyte](http://purl.obolibrary.org/obo/CL_4033015) SubClassOf [retinal cell](http://purl.obolibrary.org/obo/CL_0009004) + +- [retinal astrocyte](http://purl.obolibrary.org/obo/CL_4033015) SubClassOf [astrocyte](http://purl.obolibrary.org/obo/CL_0000127) + +- [retinal astrocyte](http://purl.obolibrary.org/obo/CL_4033015) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [retina](http://purl.obolibrary.org/obo/UBERON_0000966) + + +### ribonucleic acid `http://purl.obolibrary.org/obo/CHEBI_33697` +#### Removed +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ribose nucleic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ribonukleinsaeure" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) [label](http://www.w3.org/2000/01/rdf-schema#label) "ribonucleic acid" + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "RNA" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "RNS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33697" + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ribonucleic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ribonucleic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pentosenucleic acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "yeast nucleic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "RNA" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:63231-63-0" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ribonucleic acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [canonical ribonucleoside residue](http://purl.obolibrary.org/obo/CHEBI_33792) + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [canonical ribonucleotide residue](http://purl.obolibrary.org/obo/CHEBI_50299) + +- [ribonucleic acid](http://purl.obolibrary.org/obo/CHEBI_33697) SubClassOf [nucleic acid](http://purl.obolibrary.org/obo/CHEBI_33696) + + + +### role `http://purl.obolibrary.org/obo/CHEBI_50906` +#### Removed +- [role](http://purl.obolibrary.org/obo/CHEBI_50906) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50906" + +- [role](http://purl.obolibrary.org/obo/CHEBI_50906) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [role](http://purl.obolibrary.org/obo/CHEBI_50906) [label](http://www.w3.org/2000/01/rdf-schema#label) "role" + +- [role](http://purl.obolibrary.org/obo/CHEBI_50906) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A role is particular behaviour which a material entity may exhibit." + +- [role](http://purl.obolibrary.org/obo/CHEBI_50906) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + + + +### s-block element atom `http://purl.obolibrary.org/obo/CHEBI_33559` +#### Removed +- [s-block element atom](http://purl.obolibrary.org/obo/CHEBI_33559) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [s-block element atom](http://purl.obolibrary.org/obo/CHEBI_33559) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [s-block element atom](http://purl.obolibrary.org/obo/CHEBI_33559) [label](http://www.w3.org/2000/01/rdf-schema#label) "s-block element atom" + +- [s-block element atom](http://purl.obolibrary.org/obo/CHEBI_33559) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "s-block elements" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [s-block element atom](http://purl.obolibrary.org/obo/CHEBI_33559) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33559" + +- [s-block element atom](http://purl.obolibrary.org/obo/CHEBI_33559) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "s-block element" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [s-block element atom](http://purl.obolibrary.org/obo/CHEBI_33559) + +- [s-block element atom](http://purl.obolibrary.org/obo/CHEBI_33559) SubClassOf [atom](http://purl.obolibrary.org/obo/CHEBI_33250) + + + +### s-block molecular entity `http://purl.obolibrary.org/obo/CHEBI_33674` +#### Removed +- [s-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33674) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "s-block molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [s-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33674) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "s-block molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [s-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33674) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "s-block molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [s-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33674) [label](http://www.w3.org/2000/01/rdf-schema#label) "s-block molecular entity" + +- [s-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33674) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [s-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33674) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "s-block molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [s-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33674) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "s-block compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [s-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33674) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33674" + +- [s-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33674) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [s-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33674) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "s-block compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [s-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33674) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- Class: [s-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33674) + +- [s-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33674) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [s-block element atom](http://purl.obolibrary.org/obo/CHEBI_33559) + +- [s-block molecular entity](http://purl.obolibrary.org/obo/CHEBI_33674) SubClassOf [main group molecular entity](http://purl.obolibrary.org/obo/CHEBI_33579) + + + +### salivary gland cell `http://purl.obolibrary.org/obo/CL_0009005` +#### Removed +- [salivary gland cell](http://purl.obolibrary.org/obo/CL_0009005) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### salt `http://purl.obolibrary.org/obo/CHEBI_24866` +#### Removed +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A salt is an assembly of cations and anions." + +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:24866" + +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) [label](http://www.w3.org/2000/01/rdf-schema#label) "salt" + +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ionic compound" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sal" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "salts" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "salt" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ionic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Salz" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sel" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sels" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Salze" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [salt](http://purl.obolibrary.org/obo/CHEBI_24866) + +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [anion](http://purl.obolibrary.org/obo/CHEBI_22563) + +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [cation](http://purl.obolibrary.org/obo/CHEBI_36916) + +- [salt](http://purl.obolibrary.org/obo/CHEBI_24866) SubClassOf [heteroatomic molecular entity](http://purl.obolibrary.org/obo/CHEBI_37577) + + + +### salt gland `http://purl.obolibrary.org/obo/UBERON_0004758` +#### Removed +- [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) [never in taxon](http://purl.obolibrary.org/obo/RO_0002161) [Mammalia](http://purl.obolibrary.org/obo/NCBITaxon_40674) + +- [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [organ_slim](http://purl.obolibrary.org/obo/uberon/core#organ_slim) + +- [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0004758" + +- [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Salt_gland" + +- [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GAID:1235" + +- [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001204" + +- [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [functional_classification](http://purl.obolibrary.org/obo/uberon/core#functional_classification) + +- [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An organ for excreting excess salts. It is found in elasmobranchs, seabirds, and some reptiles.[WP]." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Salt_gland" + +- [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) [label](http://www.w3.org/2000/01/rdf-schema#label) "salt gland" + +- [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) [UBPROP_0000008](http://purl.obolibrary.org/obo/UBPROP_0000008) "In sharks, salt glands are found in the rectum, but in birds and reptiles, they are found in or on the skull, in the area of the eyes, nostrils or mouth. In crocodiles, the salt is excreted through the tongue. Such glands work by active transport via sodium-potassium pump that moves salt from the blood into the gland, where it can be excreted as a concentrated solution. Salt glands function to keep salt balance, and allow marine vertebrates to drink seawater" + +- [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D012491" + +- Class: [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) + +- [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) EquivalentTo [gland](http://purl.obolibrary.org/obo/UBERON_0002530) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055078)) + +- [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) SubClassOf [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Vertebrata ](http://purl.obolibrary.org/obo/NCBITaxon_7742) + +- [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) SubClassOf [capable of](http://purl.obolibrary.org/obo/RO_0002215) some [sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055078) + +- [salt gland](http://purl.obolibrary.org/obo/UBERON_0004758) SubClassOf [gland](http://purl.obolibrary.org/obo/UBERON_0002530) + + + +### salt transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_1901702` +#### Removed +- [salt transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901702) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of salt from one side of a membrane to the other." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pr" + +- [salt transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901702) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901702" + +- [salt transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901702) [label](http://www.w3.org/2000/01/rdf-schema#label) "salt transmembrane transporter activity" + +- [salt transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901702) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "pr" + +- [salt transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901702) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [salt transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901702) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-12-13T15:14:47Z" + +- Class: [salt transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901702) + +- [salt transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901702) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [salt](http://purl.obolibrary.org/obo/CHEBI_24866)) + +- [salt transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901702) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [salt](http://purl.obolibrary.org/obo/CHEBI_24866) + +- [salt transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901702) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + + +### saturated fatty acid `http://purl.obolibrary.org/obo/CHEBI_26607` +#### Removed +- [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "SFA" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16492686" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26607" + +- [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "SFAs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "SFA" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "saturated fatty acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "saturated fatty acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "SFAs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) [label](http://www.w3.org/2000/01/rdf-schema#label) "saturated fatty acid" + +- [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "saturated fatty acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "saturated fatty acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20237329" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any fatty acid containing no carbon to carbon multiple bonds. Known to produce adverse biological effects when ingested to excess." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19763019" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) + +- [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) SubClassOf [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) + + + +### saturated fatty acid anion `http://purl.obolibrary.org/obo/CHEBI_58953` +#### Removed +- [saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58953) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58953) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:58953" + +- [saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58953) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58953) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "saturated fatty acid anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58953) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any fatty acid anion in which there is no C-C unsaturation." + +- [saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58953) [label](http://www.w3.org/2000/01/rdf-schema#label) "saturated fatty acid anion" + +- Class: [saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58953) + +- [saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58953) SubClassOf [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) + + + +### sebaceous gland cell `http://purl.obolibrary.org/obo/CL_2000021` +#### Removed +- [sebaceous gland cell](http://purl.obolibrary.org/obo/CL_2000021) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) + + + +### secondary crest myofibroblast `http://purl.obolibrary.org/obo/CL_4033016` + +#### Added +- [secondary crest myofibroblast](http://purl.obolibrary.org/obo/CL_4033016) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "SCMFs" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [abbreviation](http://purl.obolibrary.org/obo/cl#abbreviation) + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [plural term](http://purl.obolibrary.org/obo/uberon#PLURAL) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25448080" + +- [secondary crest myofibroblast](http://purl.obolibrary.org/obo/CL_4033016) [label](http://www.w3.org/2000/01/rdf-schema#label) "secondary crest myofibroblast" + +- [secondary crest myofibroblast](http://purl.obolibrary.org/obo/CL_4033016) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-9185-3994](https://orcid.org/0000-0002-9185-3994) + +- [secondary crest myofibroblast](http://purl.obolibrary.org/obo/CL_4033016) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "SCMF" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:33624948" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [abbreviation](http://purl.obolibrary.org/obo/cl#abbreviation) + +- [secondary crest myofibroblast](http://purl.obolibrary.org/obo/CL_4033016) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A myofibroblast that is part of an alveoli during alveolarization. The contractile force of this cell elongates the secondary crest, while producing a framework of elastin and tenascin. During the maturation of the septa, secondary crest myofibroblasts, together with matrix fibroblasts, secrete metalloproteinases and other ECM‐remodeling proteins to thin the septal tip ECM. The secondary crest myofibroblast continues producing elastin, eventually undergoing apoptosis during adulthood." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:33624948" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:31331942" + +- [secondary crest myofibroblast](http://purl.obolibrary.org/obo/CL_4033016) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alveolar myofibroblast" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:31331942" + +- [secondary crest myofibroblast](http://purl.obolibrary.org/obo/CL_4033016) [date](http://purl.org/dc/terms/date) "2023-03-16T09:17:47Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [secondary crest myofibroblast](http://purl.obolibrary.org/obo/CL_4033016) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "secondary-crest myofibroblast" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:31331942" + +- [secondary crest myofibroblast](http://purl.obolibrary.org/obo/CL_4033016) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- Class: [secondary crest myofibroblast](http://purl.obolibrary.org/obo/CL_4033016) + +- [secondary crest myofibroblast](http://purl.obolibrary.org/obo/CL_4033016) SubClassOf [myofibroblast cell](http://purl.obolibrary.org/obo/CL_0000186) + +- [secondary crest myofibroblast](http://purl.obolibrary.org/obo/CL_4033016) SubClassOf [participates in](http://purl.obolibrary.org/obo/RO_0000056) some [lung alveolus development](http://purl.obolibrary.org/obo/GO_0048286) + +- [secondary crest myofibroblast](http://purl.obolibrary.org/obo/CL_4033016) SubClassOf [connective tissue cell](http://purl.obolibrary.org/obo/CL_0002320) + +- [secondary crest myofibroblast](http://purl.obolibrary.org/obo/CL_4033016) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [lung connective tissue](http://purl.obolibrary.org/obo/UBERON_0000114) + + +### secondary metabolite biosynthetic process `http://purl.obolibrary.org/obo/GO_0044550` +#### Removed +- [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550) [label](http://www.w3.org/2000/01/rdf-schema#label) "secondary metabolite biosynthetic process" + +- [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "secondary metabolite biosynthesis" + +- [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-03-29T01:55:18Z" + +- [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" + +- [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +- [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0044550" + +- [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "jl" + +- Class: [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550) + +- [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550) SubClassOf [secondary metabolic process](http://purl.obolibrary.org/obo/GO_0019748) + +- [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + + +### secondary oocyte `http://purl.obolibrary.org/obo/CL_0000655` +#### Removed +- [secondary oocyte](http://purl.obolibrary.org/obo/CL_0000655) EquivalentTo [oocyte](http://purl.obolibrary.org/obo/CL_0000023) and ([has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [female meiosis II](http://purl.obolibrary.org/obo/GO_0007147)) + +- [secondary oocyte](http://purl.obolibrary.org/obo/CL_0000655) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [female meiosis II](http://purl.obolibrary.org/obo/GO_0007147) + +#### Added +- [secondary oocyte](http://purl.obolibrary.org/obo/CL_0000655) EquivalentTo [oocyte](http://purl.obolibrary.org/obo/CL_0000023) and ([has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [female meiosis II](http://purl.obolibrary.org/obo/GO_0007147)) + +- [secondary oocyte](http://purl.obolibrary.org/obo/CL_0000655) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [female meiosis II](http://purl.obolibrary.org/obo/GO_0007147) + + +### secretory cell `http://purl.obolibrary.org/obo/CL_0000151` +#### Removed +- [secretory cell](http://purl.obolibrary.org/obo/CL_0000151) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### seminiferous tubule of testis `http://purl.obolibrary.org/obo/UBERON_0001343` +#### Removed +- [seminiferous tubule of testis](http://purl.obolibrary.org/obo/UBERON_0001343) SubClassOf [contains process](http://purl.obolibrary.org/obo/BFO_0000067) some [meiotic cell cycle](http://purl.obolibrary.org/obo/GO_0051321) + + + +### sends output to `http://purl.obolibrary.org/obo/RO_0002486` +#### Removed +- [sends output to](http://purl.obolibrary.org/obo/RO_0002486) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [sends output to](http://purl.obolibrary.org/obo/RO_0002486) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### sensory receptor cell `http://purl.obolibrary.org/obo/CL_0000197` +#### Removed +- [sensory receptor cell](http://purl.obolibrary.org/obo/CL_0000197) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) + + + +### serine family amino acid `http://purl.obolibrary.org/obo/CHEBI_26650` +#### Removed +- [serine family amino acid](http://purl.obolibrary.org/obo/CHEBI_26650) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "serine family amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [serine family amino acid](http://purl.obolibrary.org/obo/CHEBI_26650) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An L-alpha-amino acid which is biosynthesised from 3-phosphoglycerate (i.e. serine, glycine, cysteine and homocysteine). A closed class." + +- [serine family amino acid](http://purl.obolibrary.org/obo/CHEBI_26650) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [serine family amino acid](http://purl.obolibrary.org/obo/CHEBI_26650) [label](http://www.w3.org/2000/01/rdf-schema#label) "serine family amino acid" + +- [serine family amino acid](http://purl.obolibrary.org/obo/CHEBI_26650) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26650" + +- [serine family amino acid](http://purl.obolibrary.org/obo/CHEBI_26650) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [serine family amino acid](http://purl.obolibrary.org/obo/CHEBI_26650) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3-phosphoglycerate family amino acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [serine family amino acid](http://purl.obolibrary.org/obo/CHEBI_26650) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3-phosphoglycerate family amino acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [serine family amino acid](http://purl.obolibrary.org/obo/CHEBI_26650) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20709681" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [serine family amino acid](http://purl.obolibrary.org/obo/CHEBI_26650) SubClassOf [proteinogenic amino acid](http://purl.obolibrary.org/obo/CHEBI_83813) + +- [serine family amino acid](http://purl.obolibrary.org/obo/CHEBI_26650) SubClassOf [L-alpha-amino acid](http://purl.obolibrary.org/obo/CHEBI_15705) + + + +### serine family amino acid biosynthetic process `http://purl.obolibrary.org/obo/GO_0009070` +#### Removed +- [serine family amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009070) SubClassOf [organonitrogen compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901566) + +- [serine family amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009070) SubClassOf [organic acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016053) + +#### Added +- [serine family amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0009070) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### serine family amino acid catabolic process `http://purl.obolibrary.org/obo/GO_0009071` +#### Removed +- [serine family amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009071) SubClassOf [organonitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_1901565) + +- [serine family amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009071) SubClassOf [organic acid catabolic process](http://purl.obolibrary.org/obo/GO_0016054) + +#### Added +- [serine family amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009071) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + + +### serine family amino acid metabolic process `http://purl.obolibrary.org/obo/GO_0009069` +#### Removed +- [serine family amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0009069) SubClassOf [organic acid metabolic process](http://purl.obolibrary.org/obo/GO_0006082) + +- [serine family amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0009069) SubClassOf [organonitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_1901564) + +#### Added +- [serine family amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0009069) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### serosa of duodenum `http://purl.obolibrary.org/obo/UBERON_0003336` + +#### Added +- [serosa of duodenum](http://purl.obolibrary.org/obo/UBERON_0003336) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [serosa of duodenum](http://purl.obolibrary.org/obo/UBERON_0003336) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + +### serotonergic neuron `http://purl.obolibrary.org/obo/CL_0000850` +#### Removed +- [serotonergic neuron](http://purl.obolibrary.org/obo/CL_0000850) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000403" + + + +### serotonin `http://purl.obolibrary.org/obo/CHEBI_28790` +#### Removed +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The 5-hydroxy derivative of tryptamine." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "5-HT" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPHAR:" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Enteramine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:1420" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "serotonine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:SRO" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C10H12N2O" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Enteramine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00780" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C1=CC(=CC=2C(=CNC12)CCN)O" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "thrombotonin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus:" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:1861995" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000259" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:50-67-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "3-(2-aminoethyl)-1H-indol-5-ol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/fbbt#IUPAC_NAME) + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "NCCc1c[nH]c2ccc(O)cc12" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [SMILES](http://purl.obolibrary.org/obo/fbbt#SMILES) + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "3-(2-aminoethyl)-1H-indol-5-ol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "5-HT" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPHAR" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "InChIKey=QZAYGJVTTNCVMB-UHFFFAOYSA-N" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [InChIKey](http://purl.obolibrary.org/obo/fbbt#InChIKey) + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "serotonine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22770225" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:143524" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [label](http://www.w3.org/2000/01/rdf-schema#label) "serotonin" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24136337" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "SEROTONIN" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "QZAYGJVTTNCVMB-UHFFFAOYSA-N" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00001429" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "thrombotonin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [InChI](http://purl.obolibrary.org/obo/fbbt#InChI) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A primary amino compound that is the 5-hydroxy derivative of tryptamine." + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "thrombocytin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:143524" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "C10H12N2O" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [FORMULA](http://purl.obolibrary.org/obo/fbbt#FORMULA) + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Serotonin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "5-Hydroxytryptamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LINCS:LSM-6589" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [mass](http://purl.obolibrary.org/obo/chebi/mass) "176.215" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:28790" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "5-Hydroxytryptamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:50-67-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "thrombocytin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus:" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:49894" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18593914" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Serotonin" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "SEROTONIN" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Serotonin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3-(2-Aminoethyl)-1H-indol-5-ol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:26652" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "176.09496" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3-(2-Aminoethyl)-1H-indol-5-ol" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG COMPOUND:" + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:SEROTONIN" + +- Class: [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) SubClassOf [primary amino compound](http://purl.obolibrary.org/obo/CHEBI_50994) + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) SubClassOf [tryptamines](http://purl.obolibrary.org/obo/CHEBI_27162) + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) SubClassOf [monoamine molecular messenger](http://purl.obolibrary.org/obo/CHEBI_25375) + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) SubClassOf [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) SubClassOf [hydroxyindoles](http://purl.obolibrary.org/obo/CHEBI_84729) + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [neurotransmitter](http://purl.obolibrary.org/obo/CHEBI_25512) + +- [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + + + +### serotonin binding `http://purl.obolibrary.org/obo/GO_0051378` +#### Removed +- [serotonin binding](http://purl.obolibrary.org/obo/GO_0051378) SubClassOf [cation binding](http://purl.obolibrary.org/obo/GO_0043169) + + + +### serotonin secretion, neurotransmission `http://purl.obolibrary.org/obo/GO_0060096` + +#### Added +- [serotonin secretion, neurotransmission](http://purl.obolibrary.org/obo/GO_0060096) EquivalentTo [neurotransmitter secretion](http://purl.obolibrary.org/obo/GO_0007269) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546)) + + +### serotonin transport `http://purl.obolibrary.org/obo/GO_0006837` +#### Removed +- [serotonin transport](http://purl.obolibrary.org/obo/GO_0006837) SubClassOf [nitrogen compound transport](http://purl.obolibrary.org/obo/GO_0071705) + +#### Added +- [serotonin transport](http://purl.obolibrary.org/obo/GO_0006837) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + +### serotonin(1+) `http://purl.obolibrary.org/obo/CHEBI_350546` +#### Removed +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2/p+1" + +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C10H13N2O" + +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[NH3+]CCc1c[nH]c2ccc(O)cc12" + +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "serotonin cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "2-(5-hydroxy-1H-indol-3-yl)ethanaminium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "serotonin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "QZAYGJVTTNCVMB-UHFFFAOYSA-O" + +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) [label](http://www.w3.org/2000/01/rdf-schema#label) "serotonin(1+)" + +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:350546" + +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+1" + +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3." + +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "177.10224" + +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) [mass](http://purl.obolibrary.org/obo/chebi/mass) "177.22250" + +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) SubClassOf [ammonium ion derivative](http://purl.obolibrary.org/obo/CHEBI_35274) + +- [serotonin(1+)](http://purl.obolibrary.org/obo/CHEBI_350546) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [serotonin](http://purl.obolibrary.org/obo/CHEBI_28790) + + + +### sesquiterpene `http://purl.obolibrary.org/obo/CHEBI_35189` +#### Removed +- [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sesquiterpeno" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A C15 terpene." + +- [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189) [label](http://www.w3.org/2000/01/rdf-schema#label) "sesquiterpene" + +- [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35189" + +- [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Sesquiterpen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sesquiterpenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sesquiterpenos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sesquiterpenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- Class: [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189) + +- [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189) SubClassOf [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) + + + +### sesquiterpene biosynthetic process `http://purl.obolibrary.org/obo/GO_0051762` +#### Removed +- [sesquiterpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0051762) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [sesquiterpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0051762) [label](http://www.w3.org/2000/01/rdf-schema#label) "sesquiterpene biosynthetic process" + +- [sesquiterpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0051762) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0051762" + +- [sesquiterpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0051762) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [sesquiterpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0051762) + +- [sesquiterpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0051762) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189)) + +- [sesquiterpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0051762) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189) + +- [sesquiterpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0051762) SubClassOf [sesquiterpene metabolic process](http://purl.obolibrary.org/obo/GO_0051761) + +- [sesquiterpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0051762) SubClassOf [terpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0046246) + + + +### sesquiterpene catabolic process `http://purl.obolibrary.org/obo/GO_0051763` +#### Removed +- [sesquiterpene catabolic process](http://purl.obolibrary.org/obo/GO_0051763) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [sesquiterpene catabolic process](http://purl.obolibrary.org/obo/GO_0051763) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [sesquiterpene catabolic process](http://purl.obolibrary.org/obo/GO_0051763) [label](http://www.w3.org/2000/01/rdf-schema#label) "sesquiterpene catabolic process" + +- [sesquiterpene catabolic process](http://purl.obolibrary.org/obo/GO_0051763) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0051763" + +- Class: [sesquiterpene catabolic process](http://purl.obolibrary.org/obo/GO_0051763) + +- [sesquiterpene catabolic process](http://purl.obolibrary.org/obo/GO_0051763) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189)) + +- [sesquiterpene catabolic process](http://purl.obolibrary.org/obo/GO_0051763) SubClassOf [terpene catabolic process](http://purl.obolibrary.org/obo/GO_0046247) + +- [sesquiterpene catabolic process](http://purl.obolibrary.org/obo/GO_0051763) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189) + +- [sesquiterpene catabolic process](http://purl.obolibrary.org/obo/GO_0051763) SubClassOf [sesquiterpene metabolic process](http://purl.obolibrary.org/obo/GO_0051761) + + + +### sesquiterpene metabolic process `http://purl.obolibrary.org/obo/GO_0051761` +#### Removed +- [sesquiterpene metabolic process](http://purl.obolibrary.org/obo/GO_0051761) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [sesquiterpene metabolic process](http://purl.obolibrary.org/obo/GO_0051761) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [sesquiterpene metabolic process](http://purl.obolibrary.org/obo/GO_0051761) [label](http://www.w3.org/2000/01/rdf-schema#label) "sesquiterpene metabolic process" + +- [sesquiterpene metabolic process](http://purl.obolibrary.org/obo/GO_0051761) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sesquiterpene metabolism" + +- [sesquiterpene metabolic process](http://purl.obolibrary.org/obo/GO_0051761) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0051761" + +- Class: [sesquiterpene metabolic process](http://purl.obolibrary.org/obo/GO_0051761) + +- [sesquiterpene metabolic process](http://purl.obolibrary.org/obo/GO_0051761) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189)) + +- [sesquiterpene metabolic process](http://purl.obolibrary.org/obo/GO_0051761) SubClassOf [terpene metabolic process](http://purl.obolibrary.org/obo/GO_0042214) + +- [sesquiterpene metabolic process](http://purl.obolibrary.org/obo/GO_0051761) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189) + + + +### sesquiterpenoid `http://purl.obolibrary.org/obo/CHEBI_26658` +#### Removed +- [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LIPID_MAPS_class:LMPR0103" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "LIPID MAPS" + +- [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups)." + +- [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26658" + +- [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sesquiterpenoids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sesquiterpenoides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658) [label](http://www.w3.org/2000/01/rdf-schema#label) "sesquiterpenoid" + +- Class: [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658) + +- [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658) SubClassOf [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) + +- [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658) SubClassOf [has_parent_hydride](http://purl.obolibrary.org/obo/chebi#has_parent_hydride) some [sesquiterpene](http://purl.obolibrary.org/obo/CHEBI_35189) + + + +### sesquiterpenoid biosynthetic process `http://purl.obolibrary.org/obo/GO_0016106` +#### Removed +- [sesquiterpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016106) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sesquiterpenoid synthesis" + +- [sesquiterpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016106) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sesquiterpenoid biosynthesis" + +- [sesquiterpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016106) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0016106" + +- [sesquiterpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016106) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [sesquiterpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016106) [label](http://www.w3.org/2000/01/rdf-schema#label) "sesquiterpenoid biosynthetic process" + +- [sesquiterpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016106) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sesquiterpenoid formation" + +- [sesquiterpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016106) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sesquiterpenoid anabolism" + +- [sesquiterpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016106) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- Class: [sesquiterpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016106) + +- [sesquiterpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016106) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658)) + +- [sesquiterpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016106) SubClassOf [terpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016114) + +- [sesquiterpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016106) SubClassOf [sesquiterpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006714) + +- [sesquiterpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016106) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658) + + + +### sesquiterpenoid catabolic process `http://purl.obolibrary.org/obo/GO_0016107` +#### Removed +- [sesquiterpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016107) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0016107" + +- [sesquiterpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016107) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [sesquiterpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016107) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sesquiterpenoid breakdown" + +- [sesquiterpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016107) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sesquiterpenoid catabolism" + +- [sesquiterpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016107) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sesquiterpenoid degradation" + +- [sesquiterpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016107) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [sesquiterpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016107) [label](http://www.w3.org/2000/01/rdf-schema#label) "sesquiterpenoid catabolic process" + +- Class: [sesquiterpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016107) + +- [sesquiterpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016107) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658)) + +- [sesquiterpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016107) SubClassOf [sesquiterpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006714) + +- [sesquiterpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016107) SubClassOf [terpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016115) + +- [sesquiterpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016107) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658) + + + +### sesquiterpenoid metabolic process `http://purl.obolibrary.org/obo/GO_0006714` +#### Removed +- [sesquiterpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006714) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sesquiterpenoid metabolism" + +- [sesquiterpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006714) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006714" + +- [sesquiterpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006714) [label](http://www.w3.org/2000/01/rdf-schema#label) "sesquiterpenoid metabolic process" + +- [sesquiterpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006714) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [sesquiterpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006714) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198547684" + +- Class: [sesquiterpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006714) + +- [sesquiterpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006714) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658)) + +- [sesquiterpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006714) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [sesquiterpenoid](http://purl.obolibrary.org/obo/CHEBI_26658) + +- [sesquiterpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006714) SubClassOf [terpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006721) + + + +### sex hormone `http://purl.obolibrary.org/obo/CHEBI_50112` +#### Removed +- [sex hormone](http://purl.obolibrary.org/obo/CHEBI_50112) [label](http://www.w3.org/2000/01/rdf-schema#label) "sex hormone" + +- [sex hormone](http://purl.obolibrary.org/obo/CHEBI_50112) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sex hormones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [sex hormone](http://purl.obolibrary.org/obo/CHEBI_50112) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50112" + +- [sex hormone](http://purl.obolibrary.org/obo/CHEBI_50112) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any hormone that is responsible for controlling sexual characteristics and reproductive function." + +- [sex hormone](http://purl.obolibrary.org/obo/CHEBI_50112) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hormones sexuelles" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [sex hormone](http://purl.obolibrary.org/obo/CHEBI_50112) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [sex hormone](http://purl.obolibrary.org/obo/CHEBI_50112) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [sex hormone](http://purl.obolibrary.org/obo/CHEBI_50112) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Sexualhormon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [sex hormone](http://purl.obolibrary.org/obo/CHEBI_50112) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Geschlechtshormon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [sex hormone](http://purl.obolibrary.org/obo/CHEBI_50112) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Geschlechtshormone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [sex hormone](http://purl.obolibrary.org/obo/CHEBI_50112) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hormone sexuelle" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [sex hormone](http://purl.obolibrary.org/obo/CHEBI_50112) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Sexualhormone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [sex hormone](http://purl.obolibrary.org/obo/CHEBI_50112) + +- [sex hormone](http://purl.obolibrary.org/obo/CHEBI_50112) SubClassOf [hormone](http://purl.obolibrary.org/obo/CHEBI_24621) + + + +### sexual sporulation `http://purl.obolibrary.org/obo/GO_0034293` +#### Removed +- [sexual sporulation](http://purl.obolibrary.org/obo/GO_0034293) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [sexual reproduction](http://purl.obolibrary.org/obo/GO_0019953) + + + +### short term hematopoietic stem cell `http://purl.obolibrary.org/obo/CL_0002033` +#### Removed +- [short term hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002033) EquivalentTo [Kit and Sca1-positive hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001008) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001)) + +- [short term hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002033) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001) + +#### Added +- [short term hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002033) EquivalentTo [Kit and Sca1-positive hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001008) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [SLAM family member 1](http://purl.obolibrary.org/obo/PR_000001833)) + +- [short term hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002033) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein kinase FLT3](http://purl.obolibrary.org/obo/PR_000002001) + + +### short-chain fatty acid `http://purl.obolibrary.org/obo/CHEBI_26666` +#### Removed +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20148677" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18203540" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "SCFAs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "SCFA" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An aliphatic monocarboxylic acid with a chain length of less than C6." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16633129" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "44.99765" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An aliphatic monocarboxylic acid with a chain length of less than C6. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid." + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "OC([*])=O" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "short-chain fatty acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26666" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CH2OR" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [label](http://www.w3.org/2000/01/rdf-schema#label) "short-chain fatty acid" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [mass](http://purl.obolibrary.org/obo/chebi/mass) "45.017" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "SCFAs" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16870803" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "SCFA" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "short-chain fatty acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) SubClassOf [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) + +- [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) + + + +### short-chain fatty acid anion `http://purl.obolibrary.org/obo/CHEBI_58951` +#### Removed +- [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:58951" + +- [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) [mass](http://purl.obolibrary.org/obo/chebi/mass) "44.010" + +- [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) [label](http://www.w3.org/2000/01/rdf-schema#label) "short-chain fatty acid anion" + +- [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) [formula](http://purl.obolibrary.org/obo/chebi/formula) "CO2R" + +- [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any fatty acid anion obtained by removal of a proton from the carboxy group of a short-chain fatty acid (chain length of less than C6)." + +- [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" + +- [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a short-chain fatty acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" + +- [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[O-]C([*])=O" + +- [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "43.98983" + +- [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "short-chain fatty acid anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) + +- [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) SubClassOf [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) + +- [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [short-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_26666) + + + +### short-chain fatty acid biosynthetic process `http://purl.obolibrary.org/obo/GO_0051790` +#### Removed +- [short-chain fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051790) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "short-chain fatty acid biosynthesis" + +- [short-chain fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051790) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "short-chain fatty acid formation" + +- [short-chain fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051790) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "short chain fatty acid biosynthetic process" + +- [short-chain fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051790) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "short-chain fatty acid anabolism" + +- [short-chain fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051790) [label](http://www.w3.org/2000/01/rdf-schema#label) "short-chain fatty acid biosynthetic process" + +- [short-chain fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051790) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "short-chain fatty acid synthesis" + +- [short-chain fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051790) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of fatty acids with a chain length of less than C6." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fatty_acid_metabolism" + +- [short-chain fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051790) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "short chain fatty acid biosynthesis" + +- [short-chain fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051790) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0051790" + +- [short-chain fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051790) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [short-chain fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051790) + +- [short-chain fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051790) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951)) + +- [short-chain fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051790) SubClassOf [short-chain fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0046459) + +- [short-chain fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051790) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) + +- [short-chain fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0051790) SubClassOf [fatty acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006633) + + + +### short-chain fatty acid catabolic process `http://purl.obolibrary.org/obo/GO_0019626` +#### Removed +- [short-chain fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0019626) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of fatty acids with a chain length of less than C6." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [short-chain fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0019626) [label](http://www.w3.org/2000/01/rdf-schema#label) "short-chain fatty acid catabolic process" + +- [short-chain fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0019626) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "short-chain fatty acid degradation" + +- [short-chain fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0019626) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0019626" + +- [short-chain fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0019626) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "short-chain fatty acid breakdown" + +- [short-chain fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0019626) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "short-chain fatty acid catabolism" + +- [short-chain fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0019626) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [short-chain fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0019626) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:ACETOACETATE-DEG-PWY" + +- Class: [short-chain fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0019626) + +- [short-chain fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0019626) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951)) + +- [short-chain fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0019626) SubClassOf [short-chain fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0046459) + +- [short-chain fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0019626) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) + +- [short-chain fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0019626) SubClassOf [fatty acid catabolic process](http://purl.obolibrary.org/obo/GO_0009062) + + + +### short-chain fatty acid metabolic process `http://purl.obolibrary.org/obo/GO_0046459` +#### Removed +- [short-chain fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0046459) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [short-chain fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0046459) [label](http://www.w3.org/2000/01/rdf-schema#label) "short-chain fatty acid metabolic process" + +- [short-chain fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0046459) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "short-chain fatty acid metabolism" + +- [short-chain fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0046459) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046459" + +- [short-chain fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0046459) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving fatty acids with a chain length of less than C6." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fatty_acid_metabolism" + +- Class: [short-chain fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0046459) + +- [short-chain fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0046459) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951)) + +- [short-chain fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0046459) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) + +- [short-chain fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0046459) SubClassOf [fatty acid metabolic process](http://purl.obolibrary.org/obo/GO_0006631) + + + +### short-chain fatty acid transmembrane transport `http://purl.obolibrary.org/obo/GO_0015913` +#### Removed +- [short-chain fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_0015913) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "short-chain fatty acid import" + +- [short-chain fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_0015913) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015913" + +- [short-chain fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_0015913) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24587"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [short-chain fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_0015913) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "short-chain fatty acid uptake" + +- [short-chain fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_0015913) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of short-chain fatty acids into a cell or organelle. Short-chain fatty acids are fatty acids with a chain length of less than C6." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [short-chain fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_0015913) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [short-chain fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_0015913) [label](http://www.w3.org/2000/01/rdf-schema#label) "short-chain fatty acid transmembrane transport" + +- Class: [short-chain fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_0015913) + +- [short-chain fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_0015913) EquivalentTo [transmembrane transport](http://purl.obolibrary.org/obo/GO_0055085) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951)) + +- [short-chain fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_0015913) SubClassOf [fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_1902001) + +- [short-chain fatty acid transmembrane transport](http://purl.obolibrary.org/obo/GO_0015913) SubClassOf [short-chain fatty acid transport](http://purl.obolibrary.org/obo/GO_0015912) + + + +### short-chain fatty acid transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015636` +#### Removed +- [short-chain fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015636) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "short-chain fatty acid uptake transporter activity" + +- [short-chain fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015636) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of short-chain fatty acids from one side of a membrane to the other. Short-chain fatty acids are fatty acids with a chain length of less than C6." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [short-chain fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015636) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "short-chain fatty acid transporter activity" + +- [short-chain fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015636) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [short-chain fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015636) [label](http://www.w3.org/2000/01/rdf-schema#label) "short-chain fatty acid transmembrane transporter activity" + +- [short-chain fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015636) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0015635" + +- [short-chain fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015636) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015636" + +- Class: [short-chain fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015636) + +- [short-chain fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015636) EquivalentTo [transporter activity](http://purl.obolibrary.org/obo/GO_0005215) and ([results in transport across](http://purl.obolibrary.org/obo/RO_0002342) some [membrane](http://purl.obolibrary.org/obo/GO_0016020)) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951)) + +- [short-chain fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015636) SubClassOf [fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015245) + +- [short-chain fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015636) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) + +- [short-chain fatty acid transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015636) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [short-chain fatty acid transport](http://purl.obolibrary.org/obo/GO_0015912) + + + +### short-chain fatty acid transport `http://purl.obolibrary.org/obo/GO_0015912` +#### Removed +- [short-chain fatty acid transport](http://purl.obolibrary.org/obo/GO_0015912) [label](http://www.w3.org/2000/01/rdf-schema#label) "short-chain fatty acid transport" + +- [short-chain fatty acid transport](http://purl.obolibrary.org/obo/GO_0015912) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of short-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Short-chain fatty acids are fatty acids with a chain length of less than C6." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [short-chain fatty acid transport](http://purl.obolibrary.org/obo/GO_0015912) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015912" + +- [short-chain fatty acid transport](http://purl.obolibrary.org/obo/GO_0015912) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [short-chain fatty acid transport](http://purl.obolibrary.org/obo/GO_0015912) + +- [short-chain fatty acid transport](http://purl.obolibrary.org/obo/GO_0015912) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951)) + +- [short-chain fatty acid transport](http://purl.obolibrary.org/obo/GO_0015912) SubClassOf [fatty acid transport](http://purl.obolibrary.org/obo/GO_0015908) + +- [short-chain fatty acid transport](http://purl.obolibrary.org/obo/GO_0015912) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [short-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58951) + + + +### signaling `http://purl.obolibrary.org/obo/GO_0023052` +#### Removed +- [signaling](http://purl.obolibrary.org/obo/GO_0023052) SubClassOf [biological_process](http://purl.obolibrary.org/obo/GO_0008150) + +#### Added +- [signaling](http://purl.obolibrary.org/obo/GO_0023052) SubClassOf [regulation of biological process](http://purl.obolibrary.org/obo/GO_0050789) + + +### signalling molecule `http://purl.obolibrary.org/obo/CHEBI_62488` +#### Removed +- [signalling molecule](http://purl.obolibrary.org/obo/CHEBI_62488) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:62488" + +- [signalling molecule](http://purl.obolibrary.org/obo/CHEBI_62488) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [signalling molecule](http://purl.obolibrary.org/obo/CHEBI_62488) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell." + +- [signalling molecule](http://purl.obolibrary.org/obo/CHEBI_62488) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "signaling molecules" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [signalling molecule](http://purl.obolibrary.org/obo/CHEBI_62488) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "signal molecule" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [signalling molecule](http://purl.obolibrary.org/obo/CHEBI_62488) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "signaling molecule" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [signalling molecule](http://purl.obolibrary.org/obo/CHEBI_62488) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [signalling molecule](http://purl.obolibrary.org/obo/CHEBI_62488) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "signal molecules" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [signalling molecule](http://purl.obolibrary.org/obo/CHEBI_62488) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "signalling molecules" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [signalling molecule](http://purl.obolibrary.org/obo/CHEBI_62488) [label](http://www.w3.org/2000/01/rdf-schema#label) "signalling molecule" + +- Class: [signalling molecule](http://purl.obolibrary.org/obo/CHEBI_62488) + +- [signalling molecule](http://purl.obolibrary.org/obo/CHEBI_62488) SubClassOf [molecular messenger](http://purl.obolibrary.org/obo/CHEBI_33280) + + + +### simple protein `http://purl.obolibrary.org/obo/CHEBI_38560` +#### Removed +- [simple protein](http://purl.obolibrary.org/obo/CHEBI_38560) [label](http://www.w3.org/2000/01/rdf-schema#label) "simple protein" + +- [simple protein](http://purl.obolibrary.org/obo/CHEBI_38560) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "simple proteins" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [simple protein](http://purl.obolibrary.org/obo/CHEBI_38560) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:38560" + +- [simple protein](http://purl.obolibrary.org/obo/CHEBI_38560) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [simple protein](http://purl.obolibrary.org/obo/CHEBI_38560) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [simple protein](http://purl.obolibrary.org/obo/CHEBI_38560) + +- [simple protein](http://purl.obolibrary.org/obo/CHEBI_38560) SubClassOf [protein](http://purl.obolibrary.org/obo/PR_000000001) + +- [simple protein](http://purl.obolibrary.org/obo/CHEBI_38560) SubClassOf [protein](http://purl.obolibrary.org/obo/CHEBI_36080) + + + +### simultaneous with `http://purl.obolibrary.org/obo/RO_0002082` +#### Removed +- [simultaneous with](http://purl.obolibrary.org/obo/RO_0002082) SubPropertyOf: [ends](http://purl.obolibrary.org/obo/RO_0002229) + +- [simultaneous with](http://purl.obolibrary.org/obo/RO_0002082) SubPropertyOf: [starts](http://purl.obolibrary.org/obo/RO_0002223) + +#### Added +- [simultaneous with](http://purl.obolibrary.org/obo/RO_0002082) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) + + +### skeleton of `http://purl.obolibrary.org/obo/RO_0002576` +#### Removed +- [skeleton of](http://purl.obolibrary.org/obo/RO_0002576) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" + +#### Added +- [skeleton of](http://purl.obolibrary.org/obo/RO_0002576) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) + + +### skin of breast `http://purl.obolibrary.org/obo/UBERON_8480030` +#### Removed +- [skin of breast](http://purl.obolibrary.org/obo/UBERON_8480030) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](http://orcid.org/0000-0002-0819-0473) + +#### Added +- [skin of breast](http://purl.obolibrary.org/obo/UBERON_8480030) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](https://orcid.org/0000-0002-0819-0473) + + +### skin of clavicle region `http://purl.obolibrary.org/obo/UBERON_8480025` +#### Removed +- [skin of clavicle region](http://purl.obolibrary.org/obo/UBERON_8480025) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](http://orcid.org/0000-0002-0819-0473) + +#### Added +- [skin of clavicle region](http://purl.obolibrary.org/obo/UBERON_8480025) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](https://orcid.org/0000-0002-0819-0473) + + +### skin of external genitalia `http://purl.obolibrary.org/obo/UBERON_8480029` +#### Removed +- [skin of external genitalia](http://purl.obolibrary.org/obo/UBERON_8480029) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](http://orcid.org/0000-0002-0819-0473) + +#### Added +- [skin of external genitalia](http://purl.obolibrary.org/obo/UBERON_8480029) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](https://orcid.org/0000-0002-0819-0473) + + +### skin of iliac crest region `http://purl.obolibrary.org/obo/UBERON_8480026` +#### Removed +- [skin of iliac crest region](http://purl.obolibrary.org/obo/UBERON_8480026) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](http://orcid.org/0000-0002-0819-0473) + +#### Added +- [skin of iliac crest region](http://purl.obolibrary.org/obo/UBERON_8480026) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](https://orcid.org/0000-0002-0819-0473) + + +### small intestine serosal dendritic cell `http://purl.obolibrary.org/obo/CL_0002466` +#### Removed +- [small intestine serosal dendritic cell](http://purl.obolibrary.org/obo/CL_0002466) EquivalentTo [CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0002465) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C](http://purl.obolibrary.org/obo/PR_000001006)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010)) + +- [small intestine serosal dendritic cell](http://purl.obolibrary.org/obo/CL_0002466) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010) + +#### Added +- [small intestine serosal dendritic cell](http://purl.obolibrary.org/obo/CL_0002466) EquivalentTo [CD11b-positive dendritic cell](http://purl.obolibrary.org/obo/CL_0002465) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C](http://purl.obolibrary.org/obo/PR_000001006)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) + +- [small intestine serosal dendritic cell](http://purl.obolibrary.org/obo/CL_0002466) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-E](http://purl.obolibrary.org/obo/PR_000001010) + + +### small pre-B-II cell `http://purl.obolibrary.org/obo/CL_0000954` +#### Removed +- [small pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000954) EquivalentTo [pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000955) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [V(D)J recombination-activating protein 1](http://purl.obolibrary.org/obo/PR_000003457)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [V(D)J recombination-activating protein 2](http://purl.obolibrary.org/obo/PR_000003460)) and ([participates in](http://purl.obolibrary.org/obo/RO_0000056) some [immunoglobulin light chain V-J recombination](http://purl.obolibrary.org/obo/GO_0071708)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [B cell receptor complex](http://purl.obolibrary.org/obo/GO_0019815)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [pre-B cell receptor complex](http://purl.obolibrary.org/obo/GO_0035369)) + +- [small pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000954) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [pre-B cell receptor complex](http://purl.obolibrary.org/obo/GO_0035369) + +- [small pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000954) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [B cell receptor complex](http://purl.obolibrary.org/obo/GO_0019815) + +#### Added +- [small pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000954) EquivalentTo [pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000955) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [V(D)J recombination-activating protein 1](http://purl.obolibrary.org/obo/PR_000003457)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [V(D)J recombination-activating protein 2](http://purl.obolibrary.org/obo/PR_000003460)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [B cell receptor complex](http://purl.obolibrary.org/obo/GO_0019815)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [pre-B cell receptor complex](http://purl.obolibrary.org/obo/GO_0035369)) and ([participates in](http://purl.obolibrary.org/obo/RO_0000056) some [immunoglobulin light chain V-J recombination](http://purl.obolibrary.org/obo/GO_0071708)) + +- [small pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000954) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [B cell receptor complex](http://purl.obolibrary.org/obo/GO_0019815) + +- [small pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000954) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [pre-B cell receptor complex](http://purl.obolibrary.org/obo/GO_0035369) + + +### smiles `http://purl.obolibrary.org/obo/chebi/smiles` +#### Removed +- AnnotationProperty: [smiles](http://purl.obolibrary.org/obo/chebi/smiles) + + + +### smooth muscle cell `http://purl.obolibrary.org/obo/CL_0000192` +#### Removed +- [smooth muscle cell](http://purl.obolibrary.org/obo/CL_0000192) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000191" + + + +### smooth muscle tissue of lobular bronchiole `http://purl.obolibrary.org/obo/UBERON_8600003` +#### Removed +- [smooth muscle tissue of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600003) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](http://orcid.org/0000-0001-6677-8489) + +#### Added +- [smooth muscle tissue of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600003) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + + +### sodium atom `http://purl.obolibrary.org/obo/CHEBI_26708` +#### Removed +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "KEAYESYHFKHZAL-UHFFFAOYSA-N" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [label](http://www.w3.org/2000/01/rdf-schema#label) "sodium atom" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [mass](http://purl.obolibrary.org/obo/chebi/mass) "22.98977" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[Na]" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "11Na" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "22.98977" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01330" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Natrium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:16221" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Na" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "natrium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26708" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WebElements:Na" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/Na" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sodium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sodium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [formula](http://purl.obolibrary.org/obo/chebi/formula) "Na" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7440-23-5" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sodio" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- Class: [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [macronutrient](http://purl.obolibrary.org/obo/CHEBI_33937) + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) + +- [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) SubClassOf [alkali metal atom](http://purl.obolibrary.org/obo/CHEBI_22314) + + + +### sodium channel activity `http://purl.obolibrary.org/obo/GO_0005272` +#### Removed +- [sodium channel activity](http://purl.obolibrary.org/obo/GO_0005272) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-3295580" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "TRPM4,5 transport extracellular Na+ to cytosol" + +- [sodium channel activity](http://purl.obolibrary.org/obo/GO_0005272) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-2730664" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol" + +- [sodium channel activity](http://purl.obolibrary.org/obo/GO_0005272) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0005272" + +- [sodium channel activity](http://purl.obolibrary.org/obo/GO_0005272) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0815340729" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_transport" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:BHF" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pr" + +- [sodium channel activity](http://purl.obolibrary.org/obo/GO_0005272) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [sodium channel activity](http://purl.obolibrary.org/obo/GO_0005272) [label](http://www.w3.org/2000/01/rdf-schema#label) "sodium channel activity" + +- Class: [sodium channel activity](http://purl.obolibrary.org/obo/GO_0005272) + +- [sodium channel activity](http://purl.obolibrary.org/obo/GO_0005272) EquivalentTo [channel activity](http://purl.obolibrary.org/obo/GO_0015267) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101)) + +- [sodium channel activity](http://purl.obolibrary.org/obo/GO_0005272) SubClassOf [monoatomic cation channel activity](http://purl.obolibrary.org/obo/GO_0005261) + +- [sodium channel activity](http://purl.obolibrary.org/obo/GO_0005272) SubClassOf [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081) + + + +### sodium channel complex `http://purl.obolibrary.org/obo/GO_0034706` +#### Removed +- [sodium channel complex](http://purl.obolibrary.org/obo/GO_0034706) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "cellular_component" + +- [sodium channel complex](http://purl.obolibrary.org/obo/GO_0034706) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0034706" + +- [sodium channel complex](http://purl.obolibrary.org/obo/GO_0034706) [label](http://www.w3.org/2000/01/rdf-schema#label) "sodium channel complex" + +- [sodium channel complex](http://purl.obolibrary.org/obo/GO_0034706) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An ion channel complex through which sodium ions pass." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- Class: [sodium channel complex](http://purl.obolibrary.org/obo/GO_0034706) + +- [sodium channel complex](http://purl.obolibrary.org/obo/GO_0034706) EquivalentTo [protein-containing complex](http://purl.obolibrary.org/obo/GO_0032991) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [sodium channel activity](http://purl.obolibrary.org/obo/GO_0005272)) + +- [sodium channel complex](http://purl.obolibrary.org/obo/GO_0034706) SubClassOf [capable of](http://purl.obolibrary.org/obo/RO_0002215) some [sodium channel activity](http://purl.obolibrary.org/obo/GO_0005272) + +- [sodium channel complex](http://purl.obolibrary.org/obo/GO_0034706) SubClassOf [cation channel complex](http://purl.obolibrary.org/obo/GO_0034703) + + + +### sodium channel inhibitor activity `http://purl.obolibrary.org/obo/GO_0019871` +#### Removed +- [sodium channel inhibitor activity](http://purl.obolibrary.org/obo/GO_0019871) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0019868" + +- [sodium channel inhibitor activity](http://purl.obolibrary.org/obo/GO_0019871) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [sodium channel inhibitor activity](http://purl.obolibrary.org/obo/GO_0019871) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0019871" + +- [sodium channel inhibitor activity](http://purl.obolibrary.org/obo/GO_0019871) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binds to and stops, prevents, or reduces the activity of a sodium channel." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [sodium channel inhibitor activity](http://purl.obolibrary.org/obo/GO_0019871) [label](http://www.w3.org/2000/01/rdf-schema#label) "sodium channel inhibitor activity" + +- Class: [sodium channel inhibitor activity](http://purl.obolibrary.org/obo/GO_0019871) + +- [sodium channel inhibitor activity](http://purl.obolibrary.org/obo/GO_0019871) EquivalentTo [molecular function regulator activity](http://purl.obolibrary.org/obo/GO_0098772) and ([directly negatively regulates](http://purl.obolibrary.org/obo/RO_0002630) some [sodium channel activity](http://purl.obolibrary.org/obo/GO_0005272)) + +- [sodium channel inhibitor activity](http://purl.obolibrary.org/obo/GO_0019871) SubClassOf [ion channel inhibitor activity](http://purl.obolibrary.org/obo/GO_0008200) + +- [sodium channel inhibitor activity](http://purl.obolibrary.org/obo/GO_0019871) SubClassOf [sodium channel regulator activity](http://purl.obolibrary.org/obo/GO_0017080) + +- [sodium channel inhibitor activity](http://purl.obolibrary.org/obo/GO_0019871) SubClassOf [directly negatively regulates](http://purl.obolibrary.org/obo/RO_0002630) some [sodium channel activity](http://purl.obolibrary.org/obo/GO_0005272) + + + +### sodium channel regulator activity `http://purl.obolibrary.org/obo/GO_0017080` +#### Removed +- [sodium channel regulator activity](http://purl.obolibrary.org/obo/GO_0017080) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0017080" + +- [sodium channel regulator activity](http://purl.obolibrary.org/obo/GO_0017080) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binds to and modulates the activity of a sodium channel." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [sodium channel regulator activity](http://purl.obolibrary.org/obo/GO_0017080) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [sodium channel regulator activity](http://purl.obolibrary.org/obo/GO_0017080) [label](http://www.w3.org/2000/01/rdf-schema#label) "sodium channel regulator activity" + +- Class: [sodium channel regulator activity](http://purl.obolibrary.org/obo/GO_0017080) + +- [sodium channel regulator activity](http://purl.obolibrary.org/obo/GO_0017080) EquivalentTo [molecular function regulator activity](http://purl.obolibrary.org/obo/GO_0098772) and ([directly regulates](http://purl.obolibrary.org/obo/RO_0002578) some [sodium channel activity](http://purl.obolibrary.org/obo/GO_0005272)) + +- [sodium channel regulator activity](http://purl.obolibrary.org/obo/GO_0017080) SubClassOf [ion channel regulator activity](http://purl.obolibrary.org/obo/GO_0099106) + +- [sodium channel regulator activity](http://purl.obolibrary.org/obo/GO_0017080) SubClassOf [directly regulates](http://purl.obolibrary.org/obo/RO_0002578) some [sodium channel activity](http://purl.obolibrary.org/obo/GO_0005272) + + + +### sodium ion binding `http://purl.obolibrary.org/obo/GO_0031402` +#### Removed +- [sodium ion binding](http://purl.obolibrary.org/obo/GO_0031402) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Na+ ion binding" + +- [sodium ion binding](http://purl.obolibrary.org/obo/GO_0031402) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [sodium ion binding](http://purl.obolibrary.org/obo/GO_0031402) [label](http://www.w3.org/2000/01/rdf-schema#label) "sodium ion binding" + +- [sodium ion binding](http://purl.obolibrary.org/obo/GO_0031402) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0031402" + +- [sodium ion binding](http://purl.obolibrary.org/obo/GO_0031402) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to a sodium ion (Na+)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- Class: [sodium ion binding](http://purl.obolibrary.org/obo/GO_0031402) + +- [sodium ion binding](http://purl.obolibrary.org/obo/GO_0031402) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101)) + +- [sodium ion binding](http://purl.obolibrary.org/obo/GO_0031402) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) + +- [sodium ion binding](http://purl.obolibrary.org/obo/GO_0031402) SubClassOf [alkali metal ion binding](http://purl.obolibrary.org/obo/GO_0031420) + + + +### sodium ion homeostasis `http://purl.obolibrary.org/obo/GO_0055078` +#### Removed +- [sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055078) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jid" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055078) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055078) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0055078" + +- [sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055078) [label](http://www.w3.org/2000/01/rdf-schema#label) "sodium ion homeostasis" + +- Class: [sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055078) + +- [sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055078) EquivalentTo [chemical homeostasis](http://purl.obolibrary.org/obo/GO_0048878) and ([regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101)) + +- [sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055078) SubClassOf [monoatomic cation homeostasis](http://purl.obolibrary.org/obo/GO_0055080) + +- [sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055078) SubClassOf [inorganic ion homeostasis](http://purl.obolibrary.org/obo/GO_0098771) + +- [sodium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055078) SubClassOf [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) + + + +### sodium ion transmembrane transport `http://purl.obolibrary.org/obo/GO_0035725` +#### Removed +- [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Note that this term is not intended for use in annotating lateral movement within membranes." + +- [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "bf" + +- [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725) [label](http://www.w3.org/2000/01/rdf-schema#label) "sodium ion transmembrane transport" + +- [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:vw" + +- [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sodium ion membrane transport" + +- [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2011-03-10T02:52:36Z" + +- [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0035725" + +- Class: [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725) + +- [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725) EquivalentTo [transmembrane transport](http://purl.obolibrary.org/obo/GO_0055085) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101)) + +- [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725) SubClassOf [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) + +- [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725) SubClassOf [monoatomic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098655) + +- [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725) SubClassOf [inorganic cation transmembrane transport](http://purl.obolibrary.org/obo/GO_0098662) + + + +### sodium ion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015081` +#### Removed +- [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24076"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sodium transporter activity" + +- [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015081" + +- [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081) [label](http://www.w3.org/2000/01/rdf-schema#label) "sodium ion transmembrane transporter activity" + +- [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "RHEA:34963" + +- [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0022816" + +- [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of sodium ions (Na+) from one side of a membrane to the other." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "RHEA:34963" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:BHF" + +- Class: [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081) + +- [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101)) + +- [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [sodium ion transmembrane transport](http://purl.obolibrary.org/obo/GO_0035725) + +- [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081) SubClassOf [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) + +- [sodium ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015081) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) + + + +### sodium ion transport `http://purl.obolibrary.org/obo/GO_0006814` +#### Removed +- [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "sodium:solute transport" + +- [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006814" + +- [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0016974" + +- [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "sodium:calcium exchange" + +- [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0006834" + +- [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "sodium/potassium transport" + +- [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sodium transport" + +- [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sodium channel auxiliary protein activity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) [label](http://www.w3.org/2000/01/rdf-schema#label) "sodium ion transport" + +- [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "mitochondrial sodium/calcium ion exchange" + +- Class: [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) + +- [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101)) + +- [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) + +- [sodium ion transport](http://purl.obolibrary.org/obo/GO_0006814) SubClassOf [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) + + + +### sodium molecular entity `http://purl.obolibrary.org/obo/CHEBI_26712` +#### Removed +- [sodium molecular entity](http://purl.obolibrary.org/obo/CHEBI_26712) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [sodium molecular entity](http://purl.obolibrary.org/obo/CHEBI_26712) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sodium molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [sodium molecular entity](http://purl.obolibrary.org/obo/CHEBI_26712) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sodium compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [sodium molecular entity](http://purl.obolibrary.org/obo/CHEBI_26712) [label](http://www.w3.org/2000/01/rdf-schema#label) "sodium molecular entity" + +- [sodium molecular entity](http://purl.obolibrary.org/obo/CHEBI_26712) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26712" + +- [sodium molecular entity](http://purl.obolibrary.org/obo/CHEBI_26712) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- Class: [sodium molecular entity](http://purl.obolibrary.org/obo/CHEBI_26712) + +- [sodium molecular entity](http://purl.obolibrary.org/obo/CHEBI_26712) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [sodium atom](http://purl.obolibrary.org/obo/CHEBI_26708) + +- [sodium molecular entity](http://purl.obolibrary.org/obo/CHEBI_26712) SubClassOf [alkali metal molecular entity](http://purl.obolibrary.org/obo/CHEBI_33296) + + + +### sodium salt `http://purl.obolibrary.org/obo/CHEBI_26714` +#### Removed +- [sodium salt](http://purl.obolibrary.org/obo/CHEBI_26714) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [sodium salt](http://purl.obolibrary.org/obo/CHEBI_26714) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any alkali metal salt having sodium(1+) as the cation." + +- [sodium salt](http://purl.obolibrary.org/obo/CHEBI_26714) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Natriumsalz" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [sodium salt](http://purl.obolibrary.org/obo/CHEBI_26714) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [sodium salt](http://purl.obolibrary.org/obo/CHEBI_26714) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Natriumsalze" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [sodium salt](http://purl.obolibrary.org/obo/CHEBI_26714) [label](http://www.w3.org/2000/01/rdf-schema#label) "sodium salt" + +- [sodium salt](http://purl.obolibrary.org/obo/CHEBI_26714) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sodium salts" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [sodium salt](http://purl.obolibrary.org/obo/CHEBI_26714) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26714" + +- Class: [sodium salt](http://purl.obolibrary.org/obo/CHEBI_26714) + +- [sodium salt](http://purl.obolibrary.org/obo/CHEBI_26714) SubClassOf [alkali metal salt](http://purl.obolibrary.org/obo/CHEBI_35479) + +- [sodium salt](http://purl.obolibrary.org/obo/CHEBI_26714) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) + +- [sodium salt](http://purl.obolibrary.org/obo/CHEBI_26714) SubClassOf [sodium molecular entity](http://purl.obolibrary.org/obo/CHEBI_26712) + + + +### sodium(1+) `http://purl.obolibrary.org/obo/CHEBI_29101` +#### Removed +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:29101" + +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [mass](http://purl.obolibrary.org/obo/chebi/mass) "22.98977" -#### Added -- [Axl+ dendritic cell, human](http://purl.obolibrary.org/obo/CL_0017009) [label](http://www.w3.org/2000/01/rdf-schema#label) "Axl+ dendritic cell, human" +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:9175" -- [Axl+ dendritic cell, human](http://purl.obolibrary.org/obo/CL_0017009) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A human dendritic cell that expresses the AXL and SIGLEC6 genes." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:31156637"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/Na/q+1" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28428369"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sodium(1+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:29221729"^^[string](http://www.w3.org/2001/XMLSchema#string) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [Axl+ dendritic cell, human](http://purl.obolibrary.org/obo/CL_0017009) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "AS DC, human" +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [Axl+ dendritic cell, human](http://purl.obolibrary.org/obo/CL_0017009) [date](http://purl.org/dc/elements/1.1/date) "2022-08-25T14:18:37Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Na+" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" -- [Axl+ dendritic cell, human](http://purl.obolibrary.org/obo/CL_0017009) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) [0000-0003-2473-2313](http://orcid.org/0000-0003-2473-2313) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:17341-25-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" -- Class: [Axl+ dendritic cell, human](http://purl.obolibrary.org/obo/CL_0017009) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+1" -- [Axl+ dendritic cell, human](http://purl.obolibrary.org/obo/CL_0017009) SubClassOf [expresses](http://purl.obolibrary.org/obo/RO_0002292) some [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[Na+]" -- [Axl+ dendritic cell, human](http://purl.obolibrary.org/obo/CL_0017009) SubClassOf [dendritic cell, human](http://purl.obolibrary.org/obo/CL_0001056) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "SODIUM ION" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" -- [Axl+ dendritic cell, human](http://purl.obolibrary.org/obo/CL_0017009) SubClassOf [expresses](http://purl.obolibrary.org/obo/RO_0002292) some [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sodium(I) cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -### Bm4 B cell `http://purl.obolibrary.org/obo/CL_0000966` -#### Removed -- [Bm4 B cell](http://purl.obolibrary.org/obo/CL_0000966) EquivalentTo [germinal center B cell](http://purl.obolibrary.org/obo/CL_0000844) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [somatic hypermutation of immunoglobulin genes](http://purl.obolibrary.org/obo/GO_0016446)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lactosylceramide 4-alpha-galactosyltransferase](http://purl.obolibrary.org/obo/PR_000003516)) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:NA" -- [Bm4 B cell](http://purl.obolibrary.org/obo/CL_0000966) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [somatic hypermutation of immunoglobulin genes](http://purl.obolibrary.org/obo/GO_0016446) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sodium cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -#### Added -- [Bm4 B cell](http://purl.obolibrary.org/obo/CL_0000966) EquivalentTo [germinal center B cell](http://purl.obolibrary.org/obo/CL_0000844) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [somatic hypermutation of immunoglobulin genes](http://purl.obolibrary.org/obo/GO_0016446)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lactosylceramide 4-alpha-galactosyltransferase](http://purl.obolibrary.org/obo/PR_000003516)) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [Bm4 B cell](http://purl.obolibrary.org/obo/CL_0000966) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [somatic hypermutation of immunoglobulin genes](http://purl.obolibrary.org/obo/GO_0016446) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Na(+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:17341-25-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" -### Bm5 B cell `http://purl.obolibrary.org/obo/CL_0000967` -#### Removed -- [Bm5 B cell](http://purl.obolibrary.org/obo/CL_0000967) EquivalentTo [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [germinal center B cell differentiation](http://purl.obolibrary.org/obo/GO_0002314)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [somatic hypermutation of immunoglobulin genes](http://purl.obolibrary.org/obo/GO_0016446)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [Bm5 B cell](http://purl.obolibrary.org/obo/CL_0000967) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [somatic hypermutation of immunoglobulin genes](http://purl.obolibrary.org/obo/GO_0016446) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A monoatomic monocation obtained from sodium." -- [Bm5 B cell](http://purl.obolibrary.org/obo/CL_0000967) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [germinal center B cell differentiation](http://purl.obolibrary.org/obo/GO_0002314) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:49766" -#### Added -- [Bm5 B cell](http://purl.obolibrary.org/obo/CL_0000967) EquivalentTo [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [germinal center B cell differentiation](http://purl.obolibrary.org/obo/GO_0002314)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [somatic hypermutation of immunoglobulin genes](http://purl.obolibrary.org/obo/GO_0016446)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "FKNQFGJONOIPTF-UHFFFAOYSA-N" -- [Bm5 B cell](http://purl.obolibrary.org/obo/CL_0000967) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [somatic hypermutation of immunoglobulin genes](http://purl.obolibrary.org/obo/GO_0016446) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:15196" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" -- [Bm5 B cell](http://purl.obolibrary.org/obo/CL_0000967) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [germinal center B cell differentiation](http://purl.obolibrary.org/obo/GO_0002314) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [label](http://www.w3.org/2000/01/rdf-schema#label) "sodium(1+)" +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "22.98922" -### CD27-negative gamma-delta T cell `http://purl.obolibrary.org/obo/CL_0002125` -#### Removed -- [CD27-negative gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0002125) EquivalentTo [mature gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000800) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nuclear receptor ROR-gamma isoform 2](http://purl.obolibrary.org/obo/PR_000003455)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-17 production](http://purl.obolibrary.org/obo/GO_0032620)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:26717" -- [CD27-negative gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0002125) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sodium(1+) ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -#### Added -- [CD27-negative gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0002125) EquivalentTo [mature gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000800) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nuclear receptor ROR-gamma isoform 2](http://purl.obolibrary.org/obo/PR_000003455)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [interleukin-17 production](http://purl.obolibrary.org/obo/GO_0032620)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [CD27-negative gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0002125) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C01330" +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [formula](http://purl.obolibrary.org/obo/chebi/formula) "Na" -### CD27-positive gamma-delta T cell `http://purl.obolibrary.org/obo/CL_0002124` -#### Removed -- [CD27-positive gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0002124) EquivalentTo [mature gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000800) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [type II interferon production](http://purl.obolibrary.org/obo/GO_0032609)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Na(+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [CD27-positive gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0002124) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) +- Class: [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) -#### Added -- [CD27-positive gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0002124) EquivalentTo [mature gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000800) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [type II interferon production](http://purl.obolibrary.org/obo/GO_0032609)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) SubClassOf [monoatomic monocation](http://purl.obolibrary.org/obo/CHEBI_25414) + +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) SubClassOf [alkali metal cation](http://purl.obolibrary.org/obo/CHEBI_33504) -- [CD27-positive gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0002124) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [cofactor](http://purl.obolibrary.org/obo/CHEBI_23357) -### CD4-positive helper T cell `http://purl.obolibrary.org/obo/CL_0000492` +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) SubClassOf [monovalent inorganic cation](http://purl.obolibrary.org/obo/CHEBI_60242) + +- [sodium(1+)](http://purl.obolibrary.org/obo/CHEBI_29101) SubClassOf [elemental sodium](http://purl.obolibrary.org/obo/CHEBI_37246) + + + +### solvent `http://purl.obolibrary.org/obo/CHEBI_46787` #### Removed -- [CD4-positive helper T cell](http://purl.obolibrary.org/obo/CL_0000492) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) +- [solvent](http://purl.obolibrary.org/obo/CHEBI_46787) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -#### Added -- [CD4-positive helper T cell](http://purl.obolibrary.org/obo/CL_0000492) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) +- [solvent](http://purl.obolibrary.org/obo/CHEBI_46787) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:46787" + +- [solvent](http://purl.obolibrary.org/obo/CHEBI_46787) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Loesungsmittel" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [solvent](http://purl.obolibrary.org/obo/CHEBI_46787) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Solvent" + +- [solvent](http://purl.obolibrary.org/obo/CHEBI_46787) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "solvant" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [solvent](http://purl.obolibrary.org/obo/CHEBI_46787) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A liquid that can dissolve other substances (solutes) without any change in their chemical composition." + +- [solvent](http://purl.obolibrary.org/obo/CHEBI_46787) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "solvents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [solvent](http://purl.obolibrary.org/obo/CHEBI_46787) [label](http://www.w3.org/2000/01/rdf-schema#label) "solvent" + +- [solvent](http://purl.obolibrary.org/obo/CHEBI_46787) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [solvent](http://purl.obolibrary.org/obo/CHEBI_46787) +- [solvent](http://purl.obolibrary.org/obo/CHEBI_46787) SubClassOf [application](http://purl.obolibrary.org/obo/CHEBI_33232) -### CD4-positive, alpha-beta cytotoxic T cell `http://purl.obolibrary.org/obo/CL_0000934` +- [solvent](http://purl.obolibrary.org/obo/CHEBI_46787) SubClassOf [chemical role](http://purl.obolibrary.org/obo/CHEBI_51086) + + + +### somatostatin `http://purl.obolibrary.org/obo/CHEBI_64628` #### Removed -- [CD4-positive, alpha-beta cytotoxic T cell](http://purl.obolibrary.org/obo/CL_0000934) EquivalentTo [CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000624) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [T cell mediated cytotoxicity](http://purl.obolibrary.org/obo/GO_0001913)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Somatostatin-14" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [mass](http://purl.obolibrary.org/obo/chebi/mass) "1637.87800" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "1636.71666" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:10148626" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:64628" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C16022" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22251942" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:2997" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Somatostatin" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "somatostatine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22129035" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:38916-34-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG DRUG" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "somatostatinum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "somatostatina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:38916-34-6" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "somatostatin" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_DRUG" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A fourteen-membered heterodetic cyclic peptide comprising the sequence Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys cyclised by a disulfide bridge between the two Cys residues at positions 3 and 14." + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21922516" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22147011" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [label](http://www.w3.org/2000/01/rdf-schema#label) "somatostatin" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0013072" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22509294" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [CD4-positive, alpha-beta cytotoxic T cell](http://purl.obolibrary.org/obo/CL_0000934) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D07431" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LINCS:LSM-5326" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22483686" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Somatostatin-1" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Synthetic growth hormone release-inhibiting hormone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C76H104N18O19S2" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "NHXLMOGPVYXJNR-ATOGVRKGSA-N" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) SubClassOf [peptide hormone](http://purl.obolibrary.org/obo/CHEBI_25905) + +- [somatostatin](http://purl.obolibrary.org/obo/CHEBI_64628) SubClassOf [heterodetic cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_24533) + + + +### somatostatin binding `http://purl.obolibrary.org/obo/GO_0120023` +#### Removed +- [somatostatin binding](http://purl.obolibrary.org/obo/GO_0120023) SubClassOf [peptide hormone binding](http://purl.obolibrary.org/obo/GO_0017046) #### Added -- [CD4-positive, alpha-beta cytotoxic T cell](http://purl.obolibrary.org/obo/CL_0000934) EquivalentTo [CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000624) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [T cell mediated cytotoxicity](http://purl.obolibrary.org/obo/GO_0001913)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) +- [somatostatin binding](http://purl.obolibrary.org/obo/GO_0120023) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### somatotropin secreting cell `http://purl.obolibrary.org/obo/CL_0000295` +#### Removed +- [somatotropin secreting cell](http://purl.obolibrary.org/obo/CL_0000295) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000471" -- [CD4-positive, alpha-beta cytotoxic T cell](http://purl.obolibrary.org/obo/CL_0000934) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) -### CD4-positive, alpha-beta memory T cell `http://purl.obolibrary.org/obo/CL_0000897` +### spatially coextensive with `http://purl.obolibrary.org/obo/RO_0002379` #### Removed -- [CD4-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000897) EquivalentTo [CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000624) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [increased life span](http://purl.obolibrary.org/obo/PATO_0001603)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell activation involved in immune response](http://purl.obolibrary.org/obo/GO_0002286)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) +- [spatially coextensive with](http://purl.obolibrary.org/obo/RO_0002379) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" #### Added -- [CD4-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000897) EquivalentTo [CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000624) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [increased life span](http://purl.obolibrary.org/obo/PATO_0001603)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell activation involved in immune response](http://purl.obolibrary.org/obo/GO_0002286)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) +- [spatially coextensive with](http://purl.obolibrary.org/obo/RO_0002379) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) -### CD4-positive, alpha-beta memory T cell, CD45RO-positive `http://purl.obolibrary.org/obo/CL_0001204` +### spatially disjoint from `http://purl.obolibrary.org/obo/RO_0002163` #### Removed -- [CD4-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001204) EquivalentTo [CD4-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000897) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [interleukin-2 receptor subunit beta](http://purl.obolibrary.org/obo/PR_000001381)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) +- [spatially disjoint from](http://purl.obolibrary.org/obo/RO_0002163) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall"@en #### Added -- [CD4-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001204) EquivalentTo [CD4-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000897) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [interleukin-2 receptor subunit beta](http://purl.obolibrary.org/obo/PR_000001381)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) +- [spatially disjoint from](http://purl.obolibrary.org/obo/RO_0002163) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) -### CD8-positive, alpha-beta cytokine secreting effector T cell `http://purl.obolibrary.org/obo/CL_0000908` +### sphingolipid `http://purl.obolibrary.org/obo/CHEBI_26739` #### Removed -- [CD8-positive, alpha-beta cytokine secreting effector T cell](http://purl.obolibrary.org/obo/CL_0000908) EquivalentTo [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD69 molecule](http://purl.obolibrary.org/obo/PR_000001343)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [cytokine production](http://purl.obolibrary.org/obo/GO_0001816)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) +- [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Sphingolipids are a complex family of compounds that share a common structural feature, a sphingoid base backbone." -- [CD8-positive, alpha-beta cytokine secreting effector T cell](http://purl.obolibrary.org/obo/CL_0000908) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) +- [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -#### Added -- [CD8-positive, alpha-beta cytokine secreting effector T cell](http://purl.obolibrary.org/obo/CL_0000908) EquivalentTo [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD69 molecule](http://purl.obolibrary.org/obo/PR_000001343)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [cytokine production](http://purl.obolibrary.org/obo/GO_0001816)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) +- [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sphingolipids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [CD8-positive, alpha-beta cytokine secreting effector T cell](http://purl.obolibrary.org/obo/CL_0000908) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) +- [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" +- [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26739" -### CD8-positive, alpha-beta cytotoxic T cell `http://purl.obolibrary.org/obo/CL_0000794` -#### Removed -- [CD8-positive, alpha-beta cytotoxic T cell](http://purl.obolibrary.org/obo/CL_0000794) EquivalentTo [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [perforin-1](http://purl.obolibrary.org/obo/PR_000003466)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [granzyme B](http://purl.obolibrary.org/obo/PR_000003499)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [T cell mediated cytotoxicity](http://purl.obolibrary.org/obo/GO_0001913)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [granzyme B localization to T cell secretory granule](http://purl.obolibrary.org/obo/GO_0033380)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) +- [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739) [label](http://www.w3.org/2000/01/rdf-schema#label) "sphingolipid" -- [CD8-positive, alpha-beta cytotoxic T cell](http://purl.obolibrary.org/obo/CL_0000794) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) +- Class: [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739) -#### Added -- [CD8-positive, alpha-beta cytotoxic T cell](http://purl.obolibrary.org/obo/CL_0000794) EquivalentTo [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [perforin-1](http://purl.obolibrary.org/obo/PR_000003466)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [granzyme B](http://purl.obolibrary.org/obo/PR_000003499)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [T cell mediated cytotoxicity](http://purl.obolibrary.org/obo/GO_0001913)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [granzyme B localization to T cell secretory granule](http://purl.obolibrary.org/obo/GO_0033380)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) +- [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739) SubClassOf [organonitrogen compound](http://purl.obolibrary.org/obo/CHEBI_35352) + +- [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739) SubClassOf [organooxygen compound](http://purl.obolibrary.org/obo/CHEBI_36963) -- [CD8-positive, alpha-beta cytotoxic T cell](http://purl.obolibrary.org/obo/CL_0000794) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) +- [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739) SubClassOf [lipid](http://purl.obolibrary.org/obo/CHEBI_18059) -### CD8-positive, alpha-beta memory T cell `http://purl.obolibrary.org/obo/CL_0000909` + +### sphingolipid binding `http://purl.obolibrary.org/obo/GO_0046625` #### Removed -- [CD8-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000909) EquivalentTo [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [increased life span](http://purl.obolibrary.org/obo/PATO_0001603)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell activation involved in immune response](http://purl.obolibrary.org/obo/GO_0002286)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) +- [sphingolipid binding](http://purl.obolibrary.org/obo/GO_0046625) [label](http://www.w3.org/2000/01/rdf-schema#label) "sphingolipid binding" -#### Added -- [CD8-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000909) EquivalentTo [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [increased life span](http://purl.obolibrary.org/obo/PATO_0001603)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell activation involved in immune response](http://purl.obolibrary.org/obo/GO_0002286)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) +- [sphingolipid binding](http://purl.obolibrary.org/obo/GO_0046625) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" +- [sphingolipid binding](http://purl.obolibrary.org/obo/GO_0046625) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046625" -### CD8-positive, alpha-beta memory T cell, CD45RO-positive `http://purl.obolibrary.org/obo/CL_0001203` -#### Removed -- [CD8-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001203) EquivalentTo [CD8-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000909) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [interleukin-2 receptor subunit beta](http://purl.obolibrary.org/obo/PR_000001381)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) +- [sphingolipid binding](http://purl.obolibrary.org/obo/GO_0046625) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to a sphingolipid, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" -#### Added -- [CD8-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001203) EquivalentTo [CD8-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000909) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [interleukin-2 receptor subunit beta](http://purl.obolibrary.org/obo/PR_000001381)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [interleukin-2 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001380)) +- Class: [sphingolipid binding](http://purl.obolibrary.org/obo/GO_0046625) +- [sphingolipid binding](http://purl.obolibrary.org/obo/GO_0046625) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739)) -### GABAergic neuron `http://purl.obolibrary.org/obo/CL_0000617` +- [sphingolipid binding](http://purl.obolibrary.org/obo/GO_0046625) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739) -#### Added -- [GABAergic neuron](http://purl.obolibrary.org/obo/CL_0000617) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007228"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sphingolipid binding](http://purl.obolibrary.org/obo/GO_0046625) SubClassOf [lipid binding](http://purl.obolibrary.org/obo/GO_0008289) -### Kenyon cell `http://purl.obolibrary.org/obo/CL_0000673` -#### Added -- [Kenyon cell](http://purl.obolibrary.org/obo/CL_0000673) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00003686"^^[string](http://www.w3.org/2001/XMLSchema#string) +### sphingolipid biosynthetic process `http://purl.obolibrary.org/obo/GO_0030148` +#### Removed +- [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" +- [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sphingolipid anabolism" -### acellular anatomical structure `http://purl.obolibrary.org/obo/UBERON_0000476` +- [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sphingolipid biosynthesis" -#### Added -- [acellular anatomical structure](http://purl.obolibrary.org/obo/UBERON_0000476) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) [label](http://www.w3.org/2000/01/rdf-schema#label) "sphingolipid biosynthetic process" + +- [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:PWY-5129" -- [acellular anatomical structure](http://purl.obolibrary.org/obo/UBERON_0000476) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0030148" -- [acellular anatomical structure](http://purl.obolibrary.org/obo/UBERON_0000476) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" -- [acellular anatomical structure](http://purl.obolibrary.org/obo/UBERON_0000476) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" +- [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sphingolipid synthesis" -### acellular membrane `http://purl.obolibrary.org/obo/UBERON_0005764` +- [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sphingolipid formation" -#### Added -- [acellular membrane](http://purl.obolibrary.org/obo/UBERON_0005764) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- Class: [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) -- [acellular membrane](http://purl.obolibrary.org/obo/UBERON_0005764) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739)) -- [acellular membrane](http://purl.obolibrary.org/obo/UBERON_0005764) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) SubClassOf [organonitrogen compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901566) -- [acellular membrane](http://purl.obolibrary.org/obo/UBERON_0005764) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739) +- [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) SubClassOf [membrane lipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0046467) -### alveolar ridge `http://purl.obolibrary.org/obo/UBERON_0004103` +- [sphingolipid biosynthetic process](http://purl.obolibrary.org/obo/GO_0030148) SubClassOf [sphingolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006665) + + + +### sphingolipid catabolic process `http://purl.obolibrary.org/obo/GO_0030149` #### Removed -- [alveolar ridge](http://purl.obolibrary.org/obo/UBERON_0004103) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [sphingolipid catabolic process](http://purl.obolibrary.org/obo/GO_0030149) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" +- [sphingolipid catabolic process](http://purl.obolibrary.org/obo/GO_0030149) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0030149" +- [sphingolipid catabolic process](http://purl.obolibrary.org/obo/GO_0030149) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -### anatomical border `http://purl.obolibrary.org/obo/UBERON_0036304` +- [sphingolipid catabolic process](http://purl.obolibrary.org/obo/GO_0030149) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sphingolipid catabolism" -#### Added -- [anatomical border](http://purl.obolibrary.org/obo/UBERON_0036304) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [sphingolipid catabolic process](http://purl.obolibrary.org/obo/GO_0030149) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sphingolipid degradation" -- [anatomical border](http://purl.obolibrary.org/obo/UBERON_0036304) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [sphingolipid catabolic process](http://purl.obolibrary.org/obo/GO_0030149) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sphingolipid breakdown" -- [anatomical border](http://purl.obolibrary.org/obo/UBERON_0036304) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [sphingolipid catabolic process](http://purl.obolibrary.org/obo/GO_0030149) [label](http://www.w3.org/2000/01/rdf-schema#label) "sphingolipid catabolic process" -- [anatomical border](http://purl.obolibrary.org/obo/UBERON_0036304) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- Class: [sphingolipid catabolic process](http://purl.obolibrary.org/obo/GO_0030149) +- [sphingolipid catabolic process](http://purl.obolibrary.org/obo/GO_0030149) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739)) -### anatomical cluster `http://purl.obolibrary.org/obo/UBERON_0000477` +- [sphingolipid catabolic process](http://purl.obolibrary.org/obo/GO_0030149) SubClassOf [organonitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_1901565) -#### Added -- [anatomical cluster](http://purl.obolibrary.org/obo/UBERON_0000477) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [sphingolipid catabolic process](http://purl.obolibrary.org/obo/GO_0030149) SubClassOf [sphingolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006665) -- [anatomical cluster](http://purl.obolibrary.org/obo/UBERON_0000477) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [sphingolipid catabolic process](http://purl.obolibrary.org/obo/GO_0030149) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739) -- [anatomical cluster](http://purl.obolibrary.org/obo/UBERON_0000477) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [sphingolipid catabolic process](http://purl.obolibrary.org/obo/GO_0030149) SubClassOf [membrane lipid catabolic process](http://purl.obolibrary.org/obo/GO_0046466) -- [anatomical cluster](http://purl.obolibrary.org/obo/UBERON_0000477) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) -### anatomical collection `http://purl.obolibrary.org/obo/UBERON_0034925` +### sphingolipid metabolic process `http://purl.obolibrary.org/obo/GO_0006665` +#### Removed +- [sphingolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006665) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006665" -#### Added -- [anatomical collection](http://purl.obolibrary.org/obo/UBERON_0034925) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [sphingolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006665) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sphingolipid metabolism" -- [anatomical collection](http://purl.obolibrary.org/obo/UBERON_0034925) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [sphingolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006665) [label](http://www.w3.org/2000/01/rdf-schema#label) "sphingolipid metabolic process" -- [anatomical collection](http://purl.obolibrary.org/obo/UBERON_0034925) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [sphingolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006665) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" -- [anatomical collection](http://purl.obolibrary.org/obo/UBERON_0034925) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" +- [sphingolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006665) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -### anatomical conduit `http://purl.obolibrary.org/obo/UBERON_0004111` +- Class: [sphingolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006665) -#### Added -- [anatomical conduit](http://purl.obolibrary.org/obo/UBERON_0004111) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [sphingolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006665) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739)) -- [anatomical conduit](http://purl.obolibrary.org/obo/UBERON_0004111) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [sphingolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006665) SubClassOf [membrane lipid metabolic process](http://purl.obolibrary.org/obo/GO_0006643) -- [anatomical conduit](http://purl.obolibrary.org/obo/UBERON_0004111) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [sphingolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006665) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739) -- [anatomical conduit](http://purl.obolibrary.org/obo/UBERON_0004111) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [sphingolipid metabolic process](http://purl.obolibrary.org/obo/GO_0006665) SubClassOf [organonitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_1901564) -### anatomical conduit space `http://purl.obolibrary.org/obo/UBERON_0013686` -#### Added -- [anatomical conduit space](http://purl.obolibrary.org/obo/UBERON_0013686) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +### sphingolipid transporter activity `http://purl.obolibrary.org/obo/GO_0046624` +#### Removed +- [sphingolipid transporter activity](http://purl.obolibrary.org/obo/GO_0046624) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-9695890" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "SPNS2 transports S1P from cytosol to extracellular region" -- [anatomical conduit space](http://purl.obolibrary.org/obo/UBERON_0013686) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [sphingolipid transporter activity](http://purl.obolibrary.org/obo/GO_0046624) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" -- [anatomical conduit space](http://purl.obolibrary.org/obo/UBERON_0013686) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [sphingolipid transporter activity](http://purl.obolibrary.org/obo/GO_0046624) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046624" -- [anatomical conduit space](http://purl.obolibrary.org/obo/UBERON_0013686) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [sphingolipid transporter activity](http://purl.obolibrary.org/obo/GO_0046624) [label](http://www.w3.org/2000/01/rdf-schema#label) "sphingolipid transporter activity" +- [sphingolipid transporter activity](http://purl.obolibrary.org/obo/GO_0046624) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the directed movement of sphingolipids into, out of or within a cell, or between cells. Sphingolipids are a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" -### anatomical entity `http://purl.obolibrary.org/obo/UBERON_0001062` + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" -#### Added -- [anatomical entity](http://purl.obolibrary.org/obo/UBERON_0001062) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- Class: [sphingolipid transporter activity](http://purl.obolibrary.org/obo/GO_0046624) -- [anatomical entity](http://purl.obolibrary.org/obo/UBERON_0001062) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [sphingolipid transporter activity](http://purl.obolibrary.org/obo/GO_0046624) EquivalentTo [transporter activity](http://purl.obolibrary.org/obo/GO_0005215) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739)) -- [anatomical entity](http://purl.obolibrary.org/obo/UBERON_0001062) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [sphingolipid transporter activity](http://purl.obolibrary.org/obo/GO_0046624) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sphingolipid](http://purl.obolibrary.org/obo/CHEBI_26739) -- [anatomical entity](http://purl.obolibrary.org/obo/UBERON_0001062) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [sphingolipid transporter activity](http://purl.obolibrary.org/obo/GO_0046624) SubClassOf [lipid transporter activity](http://purl.obolibrary.org/obo/GO_0005319) -### anatomical junction `http://purl.obolibrary.org/obo/UBERON_0007651` -#### Added -- [anatomical junction](http://purl.obolibrary.org/obo/UBERON_0007651) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +### splenic marginal zone macrophage `http://purl.obolibrary.org/obo/CL_0000872` +#### Removed +- [splenic marginal zone macrophage](http://purl.obolibrary.org/obo/CL_0000872) EquivalentTo [splenic macrophage](http://purl.obolibrary.org/obo/CL_0000871) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [marginal zone of spleen](http://purl.obolibrary.org/obo/UBERON_0001251)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-type lectin domain family 6 member A](http://purl.obolibrary.org/obo/PR_000001806)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrophage receptor MARCO](http://purl.obolibrary.org/obo/PR_000001884)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrophage scavenger receptor types I and II](http://purl.obolibrary.org/obo/PR_000001885)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD209 molecule-like protein B](http://purl.obolibrary.org/obo/PR_000006172)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) + +- [splenic marginal zone macrophage](http://purl.obolibrary.org/obo/CL_0000872) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) -- [anatomical junction](http://purl.obolibrary.org/obo/UBERON_0007651) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +#### Added +- [splenic marginal zone macrophage](http://purl.obolibrary.org/obo/CL_0000872) EquivalentTo [splenic macrophage](http://purl.obolibrary.org/obo/CL_0000871) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [marginal zone of spleen](http://purl.obolibrary.org/obo/UBERON_0001251)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-type lectin domain family 6 member A](http://purl.obolibrary.org/obo/PR_000001806)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrophage receptor MARCO](http://purl.obolibrary.org/obo/PR_000001884)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrophage scavenger receptor types I and II](http://purl.obolibrary.org/obo/PR_000001885)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD209 molecule-like protein B](http://purl.obolibrary.org/obo/PR_000006172)) -- [anatomical junction](http://purl.obolibrary.org/obo/UBERON_0007651) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [splenic marginal zone macrophage](http://purl.obolibrary.org/obo/CL_0000872) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) -- [anatomical junction](http://purl.obolibrary.org/obo/UBERON_0007651) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +### splenic metallophillic macrophage `http://purl.obolibrary.org/obo/CL_0000873` +#### Removed +- [splenic metallophillic macrophage](http://purl.obolibrary.org/obo/CL_0000873) EquivalentTo [splenic macrophage](http://purl.obolibrary.org/obo/CL_0000871) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [marginal zone of spleen](http://purl.obolibrary.org/obo/UBERON_0001251)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [sialoadhesin](http://purl.obolibrary.org/obo/PR_000001931)) and ([adjacent to](http://purl.obolibrary.org/obo/RO_0002220) some [white pulp of spleen](http://purl.obolibrary.org/obo/UBERON_0001959)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [C-type lectin domain family 6 member A](http://purl.obolibrary.org/obo/PR_000001806)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) -### anatomical projection `http://purl.obolibrary.org/obo/UBERON_0004529` +- [splenic metallophillic macrophage](http://purl.obolibrary.org/obo/CL_0000873) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813) #### Added -- [anatomical projection](http://purl.obolibrary.org/obo/UBERON_0004529) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [splenic metallophillic macrophage](http://purl.obolibrary.org/obo/CL_0000873) EquivalentTo [splenic macrophage](http://purl.obolibrary.org/obo/CL_0000871) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [marginal zone of spleen](http://purl.obolibrary.org/obo/UBERON_0001251)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [sialoadhesin](http://purl.obolibrary.org/obo/PR_000001931)) and ([adjacent to](http://purl.obolibrary.org/obo/RO_0002220) some [white pulp of spleen](http://purl.obolibrary.org/obo/UBERON_0001959)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [C-type lectin domain family 6 member A](http://purl.obolibrary.org/obo/PR_000001806)) -- [anatomical projection](http://purl.obolibrary.org/obo/UBERON_0004529) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [splenic metallophillic macrophage](http://purl.obolibrary.org/obo/CL_0000873) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813) -- [anatomical projection](http://purl.obolibrary.org/obo/UBERON_0004529) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) -- [anatomical projection](http://purl.obolibrary.org/obo/UBERON_0004529) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +### splenic red pulp macrophage `http://purl.obolibrary.org/obo/CL_0000874` +#### Removed +- [splenic red pulp macrophage](http://purl.obolibrary.org/obo/CL_0000874) EquivalentTo [splenic macrophage](http://purl.obolibrary.org/obo/CL_0000871) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [red pulp of spleen](http://purl.obolibrary.org/obo/UBERON_0001250)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-type lectin domain family 6 member A](http://purl.obolibrary.org/obo/PR_000001806)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrosialin](http://purl.obolibrary.org/obo/PR_000002064)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrophage mannose receptor 1](http://purl.obolibrary.org/obo/PR_000002972)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [immune response](http://purl.obolibrary.org/obo/GO_0006955)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [erythrocyte clearance](http://purl.obolibrary.org/obo/GO_0034102)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [sialoadhesin](http://purl.obolibrary.org/obo/PR_000001931)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) + +- [splenic red pulp macrophage](http://purl.obolibrary.org/obo/CL_0000874) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013) + +#### Added +- [splenic red pulp macrophage](http://purl.obolibrary.org/obo/CL_0000874) EquivalentTo [splenic macrophage](http://purl.obolibrary.org/obo/CL_0000871) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [red pulp of spleen](http://purl.obolibrary.org/obo/UBERON_0001250)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-type lectin domain family 6 member A](http://purl.obolibrary.org/obo/PR_000001806)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrosialin](http://purl.obolibrary.org/obo/PR_000002064)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrophage mannose receptor 1](http://purl.obolibrary.org/obo/PR_000002972)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [immune response](http://purl.obolibrary.org/obo/GO_0006955)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [erythrocyte clearance](http://purl.obolibrary.org/obo/GO_0034102)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [sialoadhesin](http://purl.obolibrary.org/obo/PR_000001931)) +- [splenic red pulp macrophage](http://purl.obolibrary.org/obo/CL_0000874) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013) -### anatomical row `http://purl.obolibrary.org/obo/UBERON_0034926` + +### splenic white pulp macrophage `http://purl.obolibrary.org/obo/CL_0000876` +#### Removed +- [splenic white pulp macrophage](http://purl.obolibrary.org/obo/CL_0000876) EquivalentTo [splenic macrophage](http://purl.obolibrary.org/obo/CL_0000871) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [white pulp of spleen](http://purl.obolibrary.org/obo/UBERON_0001959)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrosialin](http://purl.obolibrary.org/obo/PR_000002064)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) + +- [splenic white pulp macrophage](http://purl.obolibrary.org/obo/CL_0000876) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813) #### Added -- [anatomical row](http://purl.obolibrary.org/obo/UBERON_0034926) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [splenic white pulp macrophage](http://purl.obolibrary.org/obo/CL_0000876) EquivalentTo [splenic macrophage](http://purl.obolibrary.org/obo/CL_0000871) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [white pulp of spleen](http://purl.obolibrary.org/obo/UBERON_0001959)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [macrosialin](http://purl.obolibrary.org/obo/PR_000002064)) -- [anatomical row](http://purl.obolibrary.org/obo/UBERON_0034926) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [splenic white pulp macrophage](http://purl.obolibrary.org/obo/CL_0000876) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [adhesion G protein-coupled receptor E1](http://purl.obolibrary.org/obo/PR_000001813) -- [anatomical row](http://purl.obolibrary.org/obo/UBERON_0034926) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) -- [anatomical row](http://purl.obolibrary.org/obo/UBERON_0034926) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +### squalene `http://purl.obolibrary.org/obo/CHEBI_15440` +#### Removed +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "(6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -### anatomical space `http://purl.obolibrary.org/obo/UBERON_0000464` +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:SQUALENE" -#### Added -- [anatomical space](http://purl.obolibrary.org/obo/UBERON_0000464) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C30H50" -- [anatomical space](http://purl.obolibrary.org/obo/UBERON_0000464) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:111-02-4" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" -- [anatomical space](http://purl.obolibrary.org/obo/UBERON_0000464) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" -- [anatomical space](http://purl.obolibrary.org/obo/UBERON_0000464) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "410.39125" +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25286851" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -### anatomical structure `http://purl.obolibrary.org/obo/UBERON_0000061` +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(all-E)-2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" -#### Added -- [anatomical structure](http://purl.obolibrary.org/obo/UBERON_0000061) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24362891" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [anatomical structure](http://purl.obolibrary.org/obo/UBERON_0000061) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16341241" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [anatomical structure](http://purl.obolibrary.org/obo/UBERON_0000061) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [anatomical structure](http://purl.obolibrary.org/obo/UBERON_0000061) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:111-02-4" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Squalene" -### anatomical surface region `http://purl.obolibrary.org/obo/UBERON_0036215` +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:SQL" -#### Added -- [anatomical surface region](http://purl.obolibrary.org/obo/UBERON_0036215) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Spinacene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" -- [anatomical surface region](http://purl.obolibrary.org/obo/UBERON_0036215) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [label](http://www.w3.org/2000/01/rdf-schema#label) "squalene" -- [anatomical surface region](http://purl.obolibrary.org/obo/UBERON_0036215) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000256" -- [anatomical surface region](http://purl.obolibrary.org/obo/UBERON_0036215) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25286853" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Supraene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" -### anatomical system `http://purl.obolibrary.org/obo/UBERON_0000467` +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:15440" -#### Added -- [anatomical system](http://purl.obolibrary.org/obo/UBERON_0000467) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [mass](http://purl.obolibrary.org/obo/chebi/mass) "410.730" -- [anatomical system](http://purl.obolibrary.org/obo/UBERON_0000467) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "squalene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" -- [anatomical system](http://purl.obolibrary.org/obo/UBERON_0000467) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:15104" -- [anatomical system](http://purl.obolibrary.org/obo/UBERON_0000467) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:1728920" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:9245" -### animal cell `http://purl.obolibrary.org/obo/CL_0000548` +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:26746" -#### Added -- [animal cell](http://purl.obolibrary.org/obo/CL_0000548) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "metazoan cell" +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25987292" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [animal cell](http://purl.obolibrary.org/obo/CL_0000548) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A native cell that is part of some Metazoa." +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C30H50/c1-25(2)15-11-19-29(7)23-13-21-27(5)17-9-10-18-28(6)22-14-24-30(8)20-12-16-26(3)4/h15-18,23-24H,9-14,19-22H2,1-8H3/b27-17+,28-18+,29-23+,30-24+" +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -### anterior horn motor neuron `http://purl.obolibrary.org/obo/CL_2000048` -#### Removed -- [anterior horn motor neuron](http://purl.obolibrary.org/obo/CL_2000048) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An lower motor neuron whose soma is located in one of the ventral horns of the spinal cord and innervates skeletal muscles of the trunk or head."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DOI:10.1016/B978-0-323-42876-7.00030-2"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00751" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DOI:10.1016/B978-0-323-37101-8.00140-5"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LIPID_MAPS_instance:LMPR0106010002" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "LIPID MAPS" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://www.sciencedirect.com/topics/medicine-and-dentistry/anterior-horn-cell"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Squalene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" -#### Added -- [anterior horn motor neuron](http://purl.obolibrary.org/obo/CL_2000048) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A lower motor neuron whose soma is located in the anterior horn. Anterior horn motor neurons project from the anterior portion of the grey matter in the spinal cord to some skeletal muscles."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DOI:10.1016/B978-0-12-817962-8.00025-1"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:10843" +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "YYGNTYWPHWGJRM-AAJYLUCBSA-N" -### anterior lateral line neuromast mantle cell `http://purl.obolibrary.org/obo/CL_2000035` -#### Removed -- [anterior lateral line neuromast mantle cell](http://purl.obolibrary.org/obo/CL_2000035) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any neuromast mantle cell that is part of a anterior lateral line."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:111-02-4" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" + +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A triterpene consisting of 2,6,10,15,19,23-hexamethyltetracosane having six double bonds at the 2-, 6-, 10-, 14-, 18- and 22-positions with (all-E)-configuration." + +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C=C(/C)CC\C=C(/C)CCC=C(C)C" + +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:10795" + +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23625688" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" + +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00003755" + +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) + +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) + +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) SubClassOf [triterpene](http://purl.obolibrary.org/obo/CHEBI_35191) + +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) + +- [squalene](http://purl.obolibrary.org/obo/CHEBI_15440) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [plant metabolite](http://purl.obolibrary.org/obo/CHEBI_76924) + + + +### starts `http://purl.obolibrary.org/obo/RO_0002223` #### Added -- [anterior lateral line neuromast mantle cell](http://purl.obolibrary.org/obo/CL_2000035) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any neuromast mantle cell that is part of an anterior lateral line."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" +- [starts](http://purl.obolibrary.org/obo/RO_0002223) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) -### anterior part of tongue `http://purl.obolibrary.org/obo/UBERON_0010032` -#### Removed -- [anterior part of tongue](http://purl.obolibrary.org/obo/UBERON_0010032) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +### starts with `http://purl.obolibrary.org/obo/RO_0002224` #### Added -- [anterior part of tongue](http://purl.obolibrary.org/obo/UBERON_0010032) SubClassOf [anatomical entity](http://purl.obolibrary.org/obo/CARO_0000000) +- [starts with](http://purl.obolibrary.org/obo/RO_0002224) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) -### aortic sac `http://purl.obolibrary.org/obo/UBERON_0005432` +### stem cell of gastric gland `http://purl.obolibrary.org/obo/CL_0002183` #### Removed -- [aortic sac](http://purl.obolibrary.org/obo/UBERON_0005432) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [stem cell of gastric gland](http://purl.obolibrary.org/obo/CL_0002183) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000400" -### apocrine cell `http://purl.obolibrary.org/obo/CL_0000033` +### steroid `http://purl.obolibrary.org/obo/CHEBI_35341` #### Removed -- [apocrine cell](http://purl.obolibrary.org/obo/CL_0000033) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An apocrine cell is a secretory cell characterized loss of part of the cytoplasm during the process of secretion - secretions are budded off through the plasma membrane producing membrane bound vesicles containing the secreted substance."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tfm" - - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0721662544" +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:9263" -- [apocrine cell](http://purl.obolibrary.org/obo/CL_0000033) SubClassOf [secretory cell](http://purl.obolibrary.org/obo/CL_0000151) +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a steroid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" -#### Added -- [apocrine cell](http://purl.obolibrary.org/obo/CL_0000033) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An exocrine cell characterized by loss of part of the cytoplasm during the process of secretion. The secreted substance is accumulated at the apical end and is either budded off through the plasma membrane producing secreted vesicles or dissolved in the cytoplasm that is lost during secretion."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tfm" +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "259.24258" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25960390"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0721662544" +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13687" -- [apocrine cell](http://purl.obolibrary.org/obo/CL_0000033) SubClassOf [exocrine cell](http://purl.obolibrary.org/obo/CL_0000152) +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [label](http://www.w3.org/2000/01/rdf-schema#label) "steroid" +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "C12C(C3C(C(CC3)*)(C)CC1)CCC4C2(CCCC4)C" -### appendix smooth muscle circular layer `http://purl.obolibrary.org/obo/UBERON_8410046` +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" -#### Added -- [appendix smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410046) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A circular muscle layer of muscular coat that is part of a vermiform appendix smooth muscle." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://orcid.org/0000-0003-3440-1876"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene." -- [appendix smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410046) [label](http://www.w3.org/2000/01/rdf-schema#label) "appendix smooth muscle circular layer" +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [mass](http://purl.obolibrary.org/obo/chebi/mass) "259.450" -- [appendix smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410046) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "smooth muscle circular layer of appendix" +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Steroid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" -- [appendix smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410046) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "smooth muscle circular layer of vermiform appendix" +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C19H31R" -- [appendix smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410046) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:8410046" +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:26768" -- [appendix smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410046) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-2825-0621](https://orcid.org/0000-0002-2825-0621) +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "steroids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [appendix smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410046) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [appendix smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410046) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "smooth muscle circular layer of appendix vermiformis" +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:Steroids" -- Class: [appendix smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410046) +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00377" -- [appendix smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410046) EquivalentTo [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [vermiform appendix](http://purl.obolibrary.org/obo/UBERON_0001154)) +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35341" -- [appendix smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410046) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [vermiform appendix](http://purl.obolibrary.org/obo/UBERON_0001154) +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [appendix smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410046) SubClassOf [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) SubClassOf [organic polycyclic compound](http://purl.obolibrary.org/obo/CHEBI_51958) +- [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) SubClassOf [lipid](http://purl.obolibrary.org/obo/CHEBI_18059) -### appendix smooth muscle longitudinal layer `http://purl.obolibrary.org/obo/UBERON_8410047` -#### Added -- [appendix smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410047) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-2825-0621](https://orcid.org/0000-0002-2825-0621) -- [appendix smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410047) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "smooth muscle longitudinal layer of appendix" +### steroid acid `http://purl.obolibrary.org/obo/CHEBI_47891` +#### Removed +- [steroid acid](http://purl.obolibrary.org/obo/CHEBI_47891) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any steroid substituted by at least one carboxy group." -- [appendix smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410047) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:8410047" +- [steroid acid](http://purl.obolibrary.org/obo/CHEBI_47891) [label](http://www.w3.org/2000/01/rdf-schema#label) "steroid acid" -- [appendix smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410047) [label](http://www.w3.org/2000/01/rdf-schema#label) "appendix smooth muscle longitudinal layer" +- [steroid acid](http://purl.obolibrary.org/obo/CHEBI_47891) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:47891" -- [appendix smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410047) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "smooth muscle longitudinal layer of vermiform appendix" +- [steroid acid](http://purl.obolibrary.org/obo/CHEBI_47891) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [appendix smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410047) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "smooth muscle longitudinal layer of appendix vermiformis" +- [steroid acid](http://purl.obolibrary.org/obo/CHEBI_47891) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "steroid acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [appendix smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410047) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A longitudinal muscle layer of muscular coat that is part of a vermiform appendix smooth muscle." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://orcid.org/0000-0003-3440-1876"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [steroid acid](http://purl.obolibrary.org/obo/CHEBI_47891) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [appendix smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410047) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- Class: [steroid acid](http://purl.obolibrary.org/obo/CHEBI_47891) -- Class: [appendix smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410047) +- [steroid acid](http://purl.obolibrary.org/obo/CHEBI_47891) SubClassOf [organic acid](http://purl.obolibrary.org/obo/CHEBI_64709) -- [appendix smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410047) EquivalentTo [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [vermiform appendix](http://purl.obolibrary.org/obo/UBERON_0001154)) +- [steroid acid](http://purl.obolibrary.org/obo/CHEBI_47891) SubClassOf [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) -- [appendix smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410047) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [vermiform appendix](http://purl.obolibrary.org/obo/UBERON_0001154) +- [steroid acid](http://purl.obolibrary.org/obo/CHEBI_47891) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [steroid acid anion](http://purl.obolibrary.org/obo/CHEBI_50160) -- [appendix smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410047) SubClassOf [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) -### arch of aorta `http://purl.obolibrary.org/obo/UBERON_0001508` +### steroid acid anion `http://purl.obolibrary.org/obo/CHEBI_50160` #### Removed -- [arch of aorta](http://purl.obolibrary.org/obo/UBERON_0001508) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [steroid acid anion](http://purl.obolibrary.org/obo/CHEBI_50160) [label](http://www.w3.org/2000/01/rdf-schema#label) "steroid acid anion" -#### Added -- [arch of aorta](http://purl.obolibrary.org/obo/UBERON_0001508) SubClassOf [anatomical entity](http://purl.obolibrary.org/obo/CARO_0000000) +- [steroid acid anion](http://purl.obolibrary.org/obo/CHEBI_50160) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) +- [steroid acid anion](http://purl.obolibrary.org/obo/CHEBI_50160) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50160" -### arcuate nucleus of hypothalamus KNDy neuron `http://purl.obolibrary.org/obo/CL_4023127` -#### Removed -- [arcuate nucleus of hypothalamus KNDy neuron](http://purl.obolibrary.org/obo/CL_4023127) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "a KDNy neuron that is located in the arcuate nucleus of the hypothalamus." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30042117"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [steroid acid anion](http://purl.obolibrary.org/obo/CHEBI_50160) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any anion formed by loss of a proton from a steroid acid." -#### Added -- [arcuate nucleus of hypothalamus KNDy neuron](http://purl.obolibrary.org/obo/CL_4023127) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "a KNDy neuron that is located in the arcuate nucleus of the hypothalamus."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30042117"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [steroid acid anion](http://purl.obolibrary.org/obo/CHEBI_50160) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" +- [steroid acid anion](http://purl.obolibrary.org/obo/CHEBI_50160) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "steroid acid anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -### ascending aorta `http://purl.obolibrary.org/obo/UBERON_0001496` -#### Removed -- [ascending aorta](http://purl.obolibrary.org/obo/UBERON_0001496) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- Class: [steroid acid anion](http://purl.obolibrary.org/obo/CHEBI_50160) -#### Added -- [ascending aorta](http://purl.obolibrary.org/obo/UBERON_0001496) SubClassOf [anatomical entity](http://purl.obolibrary.org/obo/CARO_0000000) +- [steroid acid anion](http://purl.obolibrary.org/obo/CHEBI_50160) SubClassOf [carboxylic acid anion](http://purl.obolibrary.org/obo/CHEBI_29067) +- [steroid acid anion](http://purl.obolibrary.org/obo/CHEBI_50160) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [steroid acid](http://purl.obolibrary.org/obo/CHEBI_47891) -### basal cell of epithelium of lobular bronchiole `http://purl.obolibrary.org/obo/CL_1000352` + + +### steroid aldehyde `http://purl.obolibrary.org/obo/CHEBI_131565` #### Removed -- [basal cell of epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/CL_1000352) EquivalentTo [respiratory basal cell](http://purl.obolibrary.org/obo/CL_0002633) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of bronchiole](http://purl.obolibrary.org/obo/UBERON_0002051)) +- [steroid aldehyde](http://purl.obolibrary.org/obo/CHEBI_131565) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:131565" -- [basal cell of epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/CL_1000352) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of bronchiole](http://purl.obolibrary.org/obo/UBERON_0002051) +- [steroid aldehyde](http://purl.obolibrary.org/obo/CHEBI_131565) [label](http://www.w3.org/2000/01/rdf-schema#label) "steroid aldehyde" -- [basal cell of epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/CL_1000352) SubClassOf [basal cell of epithelium of bronchus](http://purl.obolibrary.org/obo/CL_1000349) +- [steroid aldehyde](http://purl.obolibrary.org/obo/CHEBI_131565) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -#### Added -- [basal cell of epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/CL_1000352) EquivalentTo [respiratory basal cell](http://purl.obolibrary.org/obo/CL_0002633) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001)) +- [steroid aldehyde](http://purl.obolibrary.org/obo/CHEBI_131565) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any steroid substituted by a formyl group." -- [basal cell of epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/CL_1000352) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001) +- [steroid aldehyde](http://purl.obolibrary.org/obo/CHEBI_131565) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [basal cell of epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/CL_1000352) SubClassOf [respiratory basal cell](http://purl.obolibrary.org/obo/CL_0002633) - - [is_inferred](http://www.geneontology.org/formats/oboInOwl#is_inferred) "true" +- [steroid aldehyde](http://purl.obolibrary.org/obo/CHEBI_131565) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "steroid aldehydes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- Class: [steroid aldehyde](http://purl.obolibrary.org/obo/CHEBI_131565) + +- [steroid aldehyde](http://purl.obolibrary.org/obo/CHEBI_131565) SubClassOf [aldehyde](http://purl.obolibrary.org/obo/CHEBI_17478) + +- [steroid aldehyde](http://purl.obolibrary.org/obo/CHEBI_131565) SubClassOf [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) -- [basal cell of epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/CL_1000352) SubClassOf [epithelial cell of tracheobronchial tree](http://purl.obolibrary.org/obo/CL_0002202) -### basal cell of epithelium of respiratory bronchiole `http://purl.obolibrary.org/obo/CL_1000351` +### steroid binding `http://purl.obolibrary.org/obo/GO_0005496` #### Removed -- [basal cell of epithelium of respiratory bronchiole](http://purl.obolibrary.org/obo/CL_1000351) SubClassOf [basal cell of epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/CL_1000352) +- [steroid binding](http://purl.obolibrary.org/obo/GO_0005496) SubClassOf [lipid binding](http://purl.obolibrary.org/obo/GO_0008289) + +- [steroid binding](http://purl.obolibrary.org/obo/GO_0005496) SubClassOf [organic cyclic compound binding](http://purl.obolibrary.org/obo/GO_0097159) #### Added -- [basal cell of epithelium of respiratory bronchiole](http://purl.obolibrary.org/obo/CL_1000351) SubClassOf [respiratory basal cell](http://purl.obolibrary.org/obo/CL_0002633) - - [is_inferred](http://www.geneontology.org/formats/oboInOwl#is_inferred) "true" +- [steroid binding](http://purl.obolibrary.org/obo/GO_0005496) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + + +### steroid catabolic process `http://purl.obolibrary.org/obo/GO_0006706` +#### Removed +- [steroid catabolic process](http://purl.obolibrary.org/obo/GO_0006706) SubClassOf [organic cyclic compound catabolic process](http://purl.obolibrary.org/obo/GO_1901361) -- [basal cell of epithelium of respiratory bronchiole](http://purl.obolibrary.org/obo/CL_1000351) SubClassOf [epithelial cell of tracheobronchial tree](http://purl.obolibrary.org/obo/CL_0002202) +- [steroid catabolic process](http://purl.obolibrary.org/obo/GO_0006706) SubClassOf [lipid catabolic process](http://purl.obolibrary.org/obo/GO_0016042) -- [basal cell of epithelium of respiratory bronchiole](http://purl.obolibrary.org/obo/CL_1000351) SubClassOf [epithelial cell of lung](http://purl.obolibrary.org/obo/CL_0000082) +#### Added +- [steroid catabolic process](http://purl.obolibrary.org/obo/GO_0006706) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) -### basal cell of epithelium of terminal bronchiole `http://purl.obolibrary.org/obo/CL_1000350` +### steroid fundamental parent `http://purl.obolibrary.org/obo/CHEBI_35508` #### Removed -- [basal cell of epithelium of terminal bronchiole](http://purl.obolibrary.org/obo/CL_1000350) SubClassOf [basal cell of epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/CL_1000352) +- [steroid fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35508) [label](http://www.w3.org/2000/01/rdf-schema#label) "steroid fundamental parent" -#### Added -- [basal cell of epithelium of terminal bronchiole](http://purl.obolibrary.org/obo/CL_1000350) SubClassOf [epithelial cell of lung](http://purl.obolibrary.org/obo/CL_0000082) +- [steroid fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35508) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35508" -- [basal cell of epithelium of terminal bronchiole](http://purl.obolibrary.org/obo/CL_1000350) SubClassOf [epithelial cell of tracheobronchial tree](http://purl.obolibrary.org/obo/CL_0002202) +- [steroid fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35508) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [basal cell of epithelium of terminal bronchiole](http://purl.obolibrary.org/obo/CL_1000350) SubClassOf [respiratory basal cell](http://purl.obolibrary.org/obo/CL_0002633) - - [is_inferred](http://www.geneontology.org/formats/oboInOwl#is_inferred) "true" +- [steroid fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35508) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "steroid fundamental parents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [steroid fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35508) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [steroid fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35508) + +- [steroid fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35508) SubClassOf [natural product fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35507) +- [steroid fundamental parent](http://purl.obolibrary.org/obo/CHEBI_35508) SubClassOf [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) -### biological pigment `http://purl.obolibrary.org/obo/CHEBI_26130` + + +### steroid hormone `http://purl.obolibrary.org/obo/CHEBI_26764` #### Removed -- [biological pigment](http://purl.obolibrary.org/obo/CHEBI_26130) [label](http://www.w3.org/2000/01/rdf-schema#label) "biological pigment" +- [steroid hormone](http://purl.obolibrary.org/obo/CHEBI_26764) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [biological pigment](http://purl.obolibrary.org/obo/CHEBI_26130) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" +- [steroid hormone](http://purl.obolibrary.org/obo/CHEBI_26764) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Steroidhormon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [biological pigment](http://purl.obolibrary.org/obo/CHEBI_26130) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26130" +- [steroid hormone](http://purl.obolibrary.org/obo/CHEBI_26764) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Steroidhormone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [biological pigment](http://purl.obolibrary.org/obo/CHEBI_26130) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An endogenous molecular entity that results in a colour of an organism as the consequence of the selective absorption of light." +- [steroid hormone](http://purl.obolibrary.org/obo/CHEBI_26764) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hormone steroide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [biological pigment](http://purl.obolibrary.org/obo/CHEBI_26130) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pigments" +- [steroid hormone](http://purl.obolibrary.org/obo/CHEBI_26764) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hormonas esteroideas" - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [biological pigment](http://purl.obolibrary.org/obo/CHEBI_26130) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) +- [steroid hormone](http://purl.obolibrary.org/obo/CHEBI_26764) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- Class: [biological pigment](http://purl.obolibrary.org/obo/CHEBI_26130) +- [steroid hormone](http://purl.obolibrary.org/obo/CHEBI_26764) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hormones steroides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [biological pigment](http://purl.obolibrary.org/obo/CHEBI_26130) SubClassOf [biophysical role](http://purl.obolibrary.org/obo/CHEBI_52208) +- [steroid hormone](http://purl.obolibrary.org/obo/CHEBI_26764) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "steroid hormones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" +- [steroid hormone](http://purl.obolibrary.org/obo/CHEBI_26764) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any steroid that acts as hormone." +- [steroid hormone](http://purl.obolibrary.org/obo/CHEBI_26764) [label](http://www.w3.org/2000/01/rdf-schema#label) "steroid hormone" -### biophysical role `http://purl.obolibrary.org/obo/CHEBI_52208` -#### Removed -- [biophysical role](http://purl.obolibrary.org/obo/CHEBI_52208) [label](http://www.w3.org/2000/01/rdf-schema#label) "biophysical role" +- [steroid hormone](http://purl.obolibrary.org/obo/CHEBI_26764) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26764" -- [biophysical role](http://purl.obolibrary.org/obo/CHEBI_52208) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" +- [steroid hormone](http://purl.obolibrary.org/obo/CHEBI_26764) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hormona esteroide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [steroid hormone](http://purl.obolibrary.org/obo/CHEBI_26764) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [hormone](http://purl.obolibrary.org/obo/CHEBI_24621) -- [biophysical role](http://purl.obolibrary.org/obo/CHEBI_52208) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#1_STAR) +- [steroid hormone](http://purl.obolibrary.org/obo/CHEBI_26764) SubClassOf [steroid](http://purl.obolibrary.org/obo/CHEBI_35341) -- [biophysical role](http://purl.obolibrary.org/obo/CHEBI_52208) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:52208" -- Class: [biophysical role](http://purl.obolibrary.org/obo/CHEBI_52208) -- [biophysical role](http://purl.obolibrary.org/obo/CHEBI_52208) SubClassOf [biological role](http://purl.obolibrary.org/obo/CHEBI_24432) +### steroid hormone secreting cell `http://purl.obolibrary.org/obo/CL_0000174` +#### Removed +- [steroid hormone secreting cell](http://purl.obolibrary.org/obo/CL_0000174) SubClassOf [endocrine cell](http://purl.obolibrary.org/obo/CL_0000163) +#### Added +- [steroid hormone secreting cell](http://purl.obolibrary.org/obo/CL_0000174) SubClassOf [secretory cell](http://purl.obolibrary.org/obo/CL_0000151) -### blood nerve barrier `http://purl.obolibrary.org/obo/UBERON_0003209` +### stomach neuroendocrine cell `http://purl.obolibrary.org/obo/CL_1000222` +#### Removed +- [stomach neuroendocrine cell](http://purl.obolibrary.org/obo/CL_1000222) SubClassOf [epithelial cell of stomach](http://purl.obolibrary.org/obo/CL_0002178) #### Added -- [blood nerve barrier](http://purl.obolibrary.org/obo/UBERON_0003209) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0003209" +- [stomach neuroendocrine cell](http://purl.obolibrary.org/obo/CL_1000222) SubClassOf [enteroendocrine cell](http://purl.obolibrary.org/obo/CL_0000164) + +- [stomach neuroendocrine cell](http://purl.obolibrary.org/obo/CL_1000222) SubClassOf [glandular cell of stomach](http://purl.obolibrary.org/obo/CL_0002659) -- [blood nerve barrier](http://purl.obolibrary.org/obo/UBERON_0003209) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" -- [blood nerve barrier](http://purl.obolibrary.org/obo/UBERON_0003209) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "blood-nerve barrier" +### stomach neuroendocrine cell differentiation `http://purl.obolibrary.org/obo/GO_0061102` + +#### Added +- [stomach neuroendocrine cell differentiation](http://purl.obolibrary.org/obo/GO_0061102) SubClassOf [enteroendocrine cell differentiation](http://purl.obolibrary.org/obo/GO_0035883) -- [blood nerve barrier](http://purl.obolibrary.org/obo/UBERON_0003209) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Barrier between the perineurium of peripheral nerves and the vascular endothelium of endoneurial capillaries. The perineurium acts as a diffusion barrier, but ion permeability at the blood-nerve barrier is still higher than at the blood-brain barrier[GO]." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO:0008065" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Blood-nerve_barrier" +### straight-chain fatty acid `http://purl.obolibrary.org/obo/CHEBI_59202` +#### Removed +- [straight-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_59202) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [blood nerve barrier](http://purl.obolibrary.org/obo/UBERON_0003209) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Blood-nerve_barrier" +- [straight-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_59202) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:59202" -- [blood nerve barrier](http://purl.obolibrary.org/obo/UBERON_0003209) [label](http://www.w3.org/2000/01/rdf-schema#label) "blood nerve barrier" +- [straight-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_59202) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [blood nerve barrier](http://purl.obolibrary.org/obo/UBERON_0003209) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D049428" +- [straight-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_59202) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "straight-chain fatty acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- Class: [blood nerve barrier](http://purl.obolibrary.org/obo/UBERON_0003209) +- [straight-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_59202) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any fatty acid whose skeletal carbon atoms form an unbranched open chain." -- [blood nerve barrier](http://purl.obolibrary.org/obo/UBERON_0003209) SubClassOf [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Chordata](http://purl.obolibrary.org/obo/NCBITaxon_7711) +- [straight-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_59202) [label](http://www.w3.org/2000/01/rdf-schema#label) "straight-chain fatty acid" -- [blood nerve barrier](http://purl.obolibrary.org/obo/UBERON_0003209) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [nervous system](http://purl.obolibrary.org/obo/UBERON_0001016) +- Class: [straight-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_59202) -- [blood nerve barrier](http://purl.obolibrary.org/obo/UBERON_0003209) SubClassOf [adjacent to](http://purl.obolibrary.org/obo/RO_0002220) some [haemolymphatic fluid](http://purl.obolibrary.org/obo/UBERON_0000179) +- [straight-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_59202) SubClassOf [fatty acid](http://purl.obolibrary.org/obo/CHEBI_35366) -- [blood nerve barrier](http://purl.obolibrary.org/obo/UBERON_0003209) SubClassOf [adjacent to](http://purl.obolibrary.org/obo/RO_0002220) some [nerve](http://purl.obolibrary.org/obo/UBERON_0001021) +- [straight-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_59202) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [straight-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_59203) -- [blood nerve barrier](http://purl.obolibrary.org/obo/UBERON_0003209) SubClassOf [cell layer](http://purl.obolibrary.org/obo/UBERON_0000119) -### bronchiole `http://purl.obolibrary.org/obo/UBERON_0002186` +### straight-chain fatty acid anion `http://purl.obolibrary.org/obo/CHEBI_59203` #### Removed -- [bronchiole](http://purl.obolibrary.org/obo/UBERON_0002186) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobular bronchiole" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7410" +- [straight-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_59203) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "straight-chain FA anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [straight-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_59203) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:59203" -- [bronchiole](http://purl.obolibrary.org/obo/UBERON_0002186) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [tracheobronchial tree](http://purl.obolibrary.org/obo/UBERON_0007196) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" +- [straight-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_59203) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "straight-chain FA anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [bronchiole](http://purl.obolibrary.org/obo/UBERON_0002186) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [bronchus](http://purl.obolibrary.org/obo/UBERON_0002185) +- [straight-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_59203) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -#### Added -- [bronchiole](http://purl.obolibrary.org/obo/UBERON_0002186) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "In some texts/references/ontologies, bronchiole has been used as an exact synonym of 'lobular bronchiole'. However, a 'lobular bronchiole' is a segment of a bronchiole." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://github.com/obophenotype/uberon/issues/2795" +- [straight-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_59203) [label](http://www.w3.org/2000/01/rdf-schema#label) "straight-chain fatty acid anion" -- [bronchiole](http://purl.obolibrary.org/obo/UBERON_0002186) [UBPROP_0000012](http://purl.obolibrary.org/obo/UBPROP_0000012) "In FMA2 and FMA3, lobular bronchiole is an exact synonym of bronchiole; however, there are two distinct terms for the corresponding epithelium." - - [external_ontology](http://www.geneontology.org/formats/oboInOwl#external_ontology) "FMA" +- [straight-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_59203) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A fatty acid anion formed by deprotonation of the carboxylic acid functional group of a straight-chain fatty acid." -- [bronchiole](http://purl.obolibrary.org/obo/UBERON_0002186) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [tracheobronchial tree](http://purl.obolibrary.org/obo/UBERON_0007196) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" +- [straight-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_59203) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) +- [straight-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_59203) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "straight-chain fatty acid anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -### brush cell of bronchus `http://purl.obolibrary.org/obo/CL_0002208` +- Class: [straight-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_59203) + +- [straight-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_59203) SubClassOf [fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_28868) + +- [straight-chain fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_59203) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [straight-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_59202) + + + +### straight-chain saturated fatty acid `http://purl.obolibrary.org/obo/CHEBI_39418` #### Removed -- [brush cell of bronchus](http://purl.obolibrary.org/obo/CL_0002208) EquivalentTo [brush cell of trachebronchial tree](http://purl.obolibrary.org/obo/CL_0002075) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of bronchus](http://purl.obolibrary.org/obo/UBERON_0002031)) +- [straight-chain saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_39418) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [brush cell of bronchus](http://purl.obolibrary.org/obo/CL_0002208) SubClassOf [brush cell of trachebronchial tree](http://purl.obolibrary.org/obo/CL_0002075) - - [is_inferred](http://www.geneontology.org/formats/oboInOwl#is_inferred) "true" +- [straight-chain saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_39418) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "straight-chain saturated fatty acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [brush cell of bronchus](http://purl.obolibrary.org/obo/CL_0002208) SubClassOf [bronchial epithelial cell](http://purl.obolibrary.org/obo/CL_0002328) - - [is_inferred](http://www.geneontology.org/formats/oboInOwl#is_inferred) "true" +- [straight-chain saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_39418) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "straight-chain saturated fatty acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" -#### Added -- [brush cell of bronchus](http://purl.obolibrary.org/obo/CL_0002208) EquivalentTo [brush cell](http://purl.obolibrary.org/obo/CL_0002204) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of bronchus](http://purl.obolibrary.org/obo/UBERON_0002031)) +- [straight-chain saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_39418) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "straight-chain saturated fatty acids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [brush cell of bronchus](http://purl.obolibrary.org/obo/CL_0002208) SubClassOf [brush cell of trachebronchial tree](http://purl.obolibrary.org/obo/CL_0002075) +- [straight-chain saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_39418) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15644336" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [brush cell of bronchus](http://purl.obolibrary.org/obo/CL_0002208) SubClassOf [bronchial epithelial cell](http://purl.obolibrary.org/obo/CL_0002328) +- [straight-chain saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_39418) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "straight-chain saturated fatty acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI:" +- [straight-chain saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_39418) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any saturated fatty acid lacking a carbon side-chain." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" -### brush cell of epithelium of lobar bronchus `http://purl.obolibrary.org/obo/CL_4033007` +- [straight-chain saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_39418) [label](http://www.w3.org/2000/01/rdf-schema#label) "straight-chain saturated fatty acid" -#### Added -- [brush cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033007) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A(n) brush cell that is part of a(n) epithelium of lobar bronchus."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15817800"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [straight-chain saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_39418) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [brush cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033007) [label](http://www.w3.org/2000/01/rdf-schema#label) "brush cell of epithelium of lobar bronchus"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [straight-chain saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_39418) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any saturated fatty acid lacking a side-chain." -- [brush cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033007) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) +- [straight-chain saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_39418) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:39418" -- Class: [brush cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033007) +- Class: [straight-chain saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_39418) -- [brush cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033007) EquivalentTo [brush cell](http://purl.obolibrary.org/obo/CL_0002204) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of lobar bronchus](http://purl.obolibrary.org/obo/UBERON_0002339)) +- [straight-chain saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_39418) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [straight-chain saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58954) -- [brush cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033007) SubClassOf [epithelial cell of lung](http://purl.obolibrary.org/obo/CL_0000082) +- [straight-chain saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_39418) SubClassOf [saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_26607) -- [brush cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033007) SubClassOf [brush cell of bronchus](http://purl.obolibrary.org/obo/CL_0002208) +- [straight-chain saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_39418) SubClassOf [straight-chain fatty acid](http://purl.obolibrary.org/obo/CHEBI_59202) -- [brush cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033007) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of lobar bronchus](http://purl.obolibrary.org/obo/UBERON_0002339) -### brush cell of lobular bronchiole `http://purl.obolibrary.org/obo/CL_0002205` +### straight-chain saturated fatty acid anion `http://purl.obolibrary.org/obo/CHEBI_58954` #### Removed -- [brush cell of lobular bronchiole](http://purl.obolibrary.org/obo/CL_0002205) EquivalentTo [brush cell of trachebronchial tree](http://purl.obolibrary.org/obo/CL_0002075) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of bronchiole](http://purl.obolibrary.org/obo/UBERON_0002051)) +- [straight-chain saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58954) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [brush cell of lobular bronchiole](http://purl.obolibrary.org/obo/CL_0002205) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of bronchiole](http://purl.obolibrary.org/obo/UBERON_0002051) +- [straight-chain saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58954) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:58954" -- [brush cell of lobular bronchiole](http://purl.obolibrary.org/obo/CL_0002205) SubClassOf [brush cell of bronchus](http://purl.obolibrary.org/obo/CL_0002208) +- [straight-chain saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58954) [label](http://www.w3.org/2000/01/rdf-schema#label) "straight-chain saturated fatty acid anion" -#### Added -- [brush cell of lobular bronchiole](http://purl.obolibrary.org/obo/CL_0002205) EquivalentTo [brush cell](http://purl.obolibrary.org/obo/CL_0002204) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001)) +- [straight-chain saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58954) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any saturated fatty acid anion lacking a carbon side-chain." + +- [straight-chain saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58954) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "straight-chain saturated fatty acid anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [brush cell of lobular bronchiole](http://purl.obolibrary.org/obo/CL_0002205) SubClassOf [brush cell of trachebronchial tree](http://purl.obolibrary.org/obo/CL_0002075) +- [straight-chain saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58954) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [brush cell of lobular bronchiole](http://purl.obolibrary.org/obo/CL_0002205) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001) +- Class: [straight-chain saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58954) +- [straight-chain saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58954) SubClassOf [saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58953) -### brush cell of terminal bronchiole `http://purl.obolibrary.org/obo/CL_0002206` +- [straight-chain saturated fatty acid anion](http://purl.obolibrary.org/obo/CHEBI_58954) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [straight-chain saturated fatty acid](http://purl.obolibrary.org/obo/CHEBI_39418) + + + +### subatomic particle `http://purl.obolibrary.org/obo/CHEBI_36342` #### Removed -- [brush cell of terminal bronchiole](http://purl.obolibrary.org/obo/CL_0002206) EquivalentTo [brush cell of trachebronchial tree](http://purl.obolibrary.org/obo/CL_0002075) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [terminal bronchiole epithelium](http://purl.obolibrary.org/obo/UBERON_0001958)) +- [subatomic particle](http://purl.obolibrary.org/obo/CHEBI_36342) [label](http://www.w3.org/2000/01/rdf-schema#label) "subatomic particle" -- [brush cell of terminal bronchiole](http://purl.obolibrary.org/obo/CL_0002206) SubClassOf [brush cell of lobular bronchiole](http://purl.obolibrary.org/obo/CL_0002205) +- [subatomic particle](http://purl.obolibrary.org/obo/CHEBI_36342) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:36342" -#### Added -- [brush cell of terminal bronchiole](http://purl.obolibrary.org/obo/CL_0002206) EquivalentTo [brush cell](http://purl.obolibrary.org/obo/CL_0002204) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [terminal bronchiole epithelium](http://purl.obolibrary.org/obo/UBERON_0001958)) +- [subatomic particle](http://purl.obolibrary.org/obo/CHEBI_36342) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A particle smaller than an atom." -- [brush cell of terminal bronchiole](http://purl.obolibrary.org/obo/CL_0002206) SubClassOf [epithelial cell of lung](http://purl.obolibrary.org/obo/CL_0000082) +- [subatomic particle](http://purl.obolibrary.org/obo/CHEBI_36342) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [brush cell of terminal bronchiole](http://purl.obolibrary.org/obo/CL_0002206) SubClassOf [brush cell of trachebronchial tree](http://purl.obolibrary.org/obo/CL_0002075) +- [subatomic particle](http://purl.obolibrary.org/obo/CHEBI_36342) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Subatomic_particle" +- [subatomic particle](http://purl.obolibrary.org/obo/CHEBI_36342) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "subatomic particles" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -### capable of `http://purl.obolibrary.org/obo/RO_0002215` +- [subatomic particle](http://purl.obolibrary.org/obo/CHEBI_36342) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) + +- Class: [subatomic particle](http://purl.obolibrary.org/obo/CHEBI_36342) + + + +### subcapsular sinus ceiling `http://purl.obolibrary.org/obo/UBERON_8410071` +#### Removed +- [subcapsular sinus ceiling](http://purl.obolibrary.org/obo/UBERON_8410071) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-2825-0621](http://orcid.org/0000-0002-2825-0621) + +#### Added +- [subcapsular sinus ceiling](http://purl.obolibrary.org/obo/UBERON_8410071) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-2825-0621](https://orcid.org/0000-0002-2825-0621) + + +### subcapsular sinus floor `http://purl.obolibrary.org/obo/UBERON_8410072` #### Removed -- [capable of](http://purl.obolibrary.org/obo/RO_0002215) SubPropertyOf: [functionally related to](http://purl.obolibrary.org/obo/RO_0002328) +- [subcapsular sinus floor](http://purl.obolibrary.org/obo/UBERON_8410072) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-2825-0621](http://orcid.org/0000-0002-2825-0621) +#### Added +- [subcapsular sinus floor](http://purl.obolibrary.org/obo/UBERON_8410072) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-2825-0621](https://orcid.org/0000-0002-2825-0621) -### cell cluster `http://purl.obolibrary.org/obo/UBERON_0034922` +### subserosa of uterine tube `http://purl.obolibrary.org/obo/UBERON_8480037` +#### Removed +- [subserosa of uterine tube](http://purl.obolibrary.org/obo/UBERON_8480037) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](http://orcid.org/0000-0002-0819-0473) #### Added -- [cell cluster](http://purl.obolibrary.org/obo/UBERON_0034922) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [subserosa of uterine tube](http://purl.obolibrary.org/obo/UBERON_8480037) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](https://orcid.org/0000-0002-0819-0473) + + +### sugar transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0051119` +#### Removed +- [sugar transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051119) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-8875902" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "SLC45A3 transports Glc from extracellular region to cytosol" -- [cell cluster](http://purl.obolibrary.org/obo/UBERON_0034922) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [sugar transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051119) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0815340729" -- [cell cluster](http://purl.obolibrary.org/obo/UBERON_0034922) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_transport" -- [cell cluster](http://purl.obolibrary.org/obo/UBERON_0034922) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" +- [sugar transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051119) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-428779" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "GLUT7 and GLUT11 transport glucose and fructose" -### cementum `http://purl.obolibrary.org/obo/UBERON_0001753` -#### Removed -- [cementum](http://purl.obolibrary.org/obo/UBERON_0001753) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [sugar transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051119) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" +- [sugar transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051119) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0051119" +- [sugar transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051119) [label](http://www.w3.org/2000/01/rdf-schema#label) "sugar transmembrane transporter activity" -### cholinergic neuron `http://purl.obolibrary.org/obo/CL_0000108` +- [sugar transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051119) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-8876319" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "SLC50A1 transports Glc from cytosol to extracellular region" -#### Added -- [cholinergic neuron](http://purl.obolibrary.org/obo/CL_0000108) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007173"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sugar transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051119) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "sugar/polyol channel activity" +- Class: [sugar transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051119) -### chromaffin cell `http://purl.obolibrary.org/obo/CL_0000166` -#### Removed -- [chromaffin cell](http://purl.obolibrary.org/obo/CL_0000166) SubClassOf [develops from](http://purl.obolibrary.org/obo/RO_0002202) some [migratory neural crest cell](http://purl.obolibrary.org/obo/CL_0000333) +- [sugar transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0051119) SubClassOf [carbohydrate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015144) -#### Added -- [chromaffin cell](http://purl.obolibrary.org/obo/CL_0000166) SubClassOf [neural crest derived neuron](http://purl.obolibrary.org/obo/CL_0000029) -### chromophil cell of anterior pituitary gland `http://purl.obolibrary.org/obo/CL_0000637` +### sulfate `http://purl.obolibrary.org/obo/CHEBI_16189` #### Removed -- [chromophil cell of anterior pituitary gland](http://purl.obolibrary.org/obo/CL_0000637) SubClassOf [neural cell](http://purl.obolibrary.org/obo/CL_0002319) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19047345" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17120760" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:3648446" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" -### ciliated columnar cell of tracheobronchial tree `http://purl.obolibrary.org/obo/CL_0002145` - -#### Added -- [ciliated columnar cell of tracheobronchial tree](http://purl.obolibrary.org/obo/CL_0002145) SubClassOf [respiratory ciliated cell](http://purl.obolibrary.org/obo/CL_4030034) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17420092" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "SO4(2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -### circular muscle layer of muscular coat `http://purl.obolibrary.org/obo/UBERON_0012368` +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Sulfate dianion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB" -#### Added -- [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inner muscularis layer" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62899" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16742508" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) [label](http://www.w3.org/2000/01/rdf-schema#label) "circular muscle layer of muscular coat" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The inner layer of the muscular coat." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0005213" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:16189" -- [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "circular muscle layer" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2" -- [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0005213" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D05963" -- [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "circular smooth muscle" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0005213" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16483812" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62899" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "inner muscularis" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62899" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16656509" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0012368" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "SULFATE ION" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" -- [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16348007" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- Class: [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12166931" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) SubClassOf [layer of smooth muscle tissue](http://purl.obolibrary.org/obo/UBERON_0034933) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid." -- [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [muscular coat](http://purl.obolibrary.org/obo/UBERON_0006660) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:9335" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19244483" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -### class switched memory B cell `http://purl.obolibrary.org/obo/CL_0000972` -#### Removed -- [class switched memory B cell](http://purl.obolibrary.org/obo/CL_0000972) EquivalentTo [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [isotype switching](http://purl.obolibrary.org/obo/GO_0045190)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19812358" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [class switched memory B cell](http://purl.obolibrary.org/obo/CL_0000972) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [isotype switching](http://purl.obolibrary.org/obo/GO_0045190) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-2" -#### Added -- [class switched memory B cell](http://purl.obolibrary.org/obo/CL_0000972) EquivalentTo [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [isotype switching](http://purl.obolibrary.org/obo/GO_0045190)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:45687" -- [class switched memory B cell](http://purl.obolibrary.org/obo/CL_0000972) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [isotype switching](http://purl.obolibrary.org/obo/GO_0045190) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11452993" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19544990" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -### clavicle bone `http://purl.obolibrary.org/obo/UBERON_0001105` -#### Removed -- [clavicle bone](http://purl.obolibrary.org/obo/UBERON_0001105) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:2120" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16534979" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0001448" -### colon smooth muscle circular layer `http://purl.obolibrary.org/obo/UBERON_8410060` +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetraoxosulfate(2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -#### Added -- [colon smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410060) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A circular muscle layer of muscular coat that is part of a colon smooth muscle." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://orcid.org/0000-0003-3440-1876"^^[string](http://www.w3.org/2001/XMLSchema#string) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [colon smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410060) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:8410060" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Sulfuric acid ion(2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB" -- [colon smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410060) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "smooth muscle circular layer of colon" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16345535" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [colon smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410060) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:3648446" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" -- [colon smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410060) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-2825-0621](https://orcid.org/0000-0002-2825-0621) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16186560" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [colon smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410060) [label](http://www.w3.org/2000/01/rdf-schema#label) "colon smooth muscle circular layer" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sulfate" -- Class: [colon smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410060) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16742518" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [colon smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410060) EquivalentTo [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [colon](http://purl.obolibrary.org/obo/UBERON_0001155)) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [large intestine smooth muscle](http://purl.obolibrary.org/obo/UBERON_0004220)) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18846414" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [colon smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410060) SubClassOf [large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012398) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18815700" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [colon smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_8410060) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [colon](http://purl.obolibrary.org/obo/UBERON_0001155) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30398859" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [mass](http://purl.obolibrary.org/obo/chebi/mass) "96.06360" -### colon smooth muscle longitudinal layer `http://purl.obolibrary.org/obo/UBERON_8410061` +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulphate ion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -#### Added -- [colon smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410061) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "smooth muscle longitudinal layer of colon" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17709180" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [colon smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410061) [label](http://www.w3.org/2000/01/rdf-schema#label) "colon smooth muscle longitudinal layer" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[O-]S([O-])(=O)=O" -- [colon smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410061) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12668033" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [colon smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410061) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:8410061" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetraoxosulfate(VI)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [colon smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410061) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-2825-0621](https://orcid.org/0000-0002-2825-0621) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [colon smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410061) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A longitudinal muscle layer of muscular coat that is part of a colon smooth muscle." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://orcid.org/0000-0003-3440-1876"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Sulfate anion(2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB" -- Class: [colon smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410061) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:15135" -- [colon smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410061) EquivalentTo [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [colon](http://purl.obolibrary.org/obo/UBERON_0001155)) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [large intestine smooth muscle](http://purl.obolibrary.org/obo/UBERON_0004220)) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16347366" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [colon smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410061) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [colon](http://purl.obolibrary.org/obo/UBERON_0001155) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:14808-79-8" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" -- [colon smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_8410061) SubClassOf [large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012399) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "QAOWNCQODCNURD-UHFFFAOYSA-L" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[SO4](2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -### common carotid artery plus branches `http://purl.obolibrary.org/obo/UBERON_0001530` -#### Removed -- [common carotid artery plus branches](http://purl.obolibrary.org/obo/UBERON_0001530) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Sulfate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:SULFATE" -### common_anatomy `http://purl.obolibrary.org/obo/uberon/core#common_anatomy` +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:14808-79-8" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" -#### Added -- AnnotationProperty: [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:SO4" -- [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) SubPropertyOf: [subset_property](http://www.geneontology.org/formats/oboInOwl#SubsetProperty) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Sulfate(2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [formula](http://purl.obolibrary.org/obo/chebi/formula) "O4S" -### connected to `http://purl.obolibrary.org/obo/RO_0002170` -#### Removed -- [connected to](http://purl.obolibrary.org/obo/RO_0002170) SubPropertyOf: [transitively_connected to](http://purl.obolibrary.org/obo/uberon/core#transitively_connected_to) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetraoxidosulfate(2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -### creator `http://purl.org/dc/elements/1.1/creator` + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -#### Added -- [creator](http://purl.org/dc/elements/1.1/creator) [shorthand](http://www.geneontology.org/formats/oboInOwl#shorthand) "dc-creator" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfate" -- [creator](http://purl.org/dc/elements/1.1/creator) [label](http://www.w3.org/2000/01/rdf-schema#label) "creator" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15093386" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [creator](http://purl.org/dc/elements/1.1/creator) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17439666" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [creator](http://purl.org/dc/elements/1.1/creator) [id](http://www.geneontology.org/formats/oboInOwl#id) "dc-creator" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "95.95283" -- [creator](http://purl.org/dc/elements/1.1/creator) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://purl.org/dc/elements/1.1/creator" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19628332" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [creator](http://purl.org/dc/elements/1.1/creator) [is_metadata_tag](http://www.geneontology.org/formats/oboInOwl#is_metadata_tag) true +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulphate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- AnnotationProperty: [creator](http://purl.org/dc/elements/1.1/creator) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18398178" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:14597181" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -### death stage `http://purl.obolibrary.org/obo/UBERON_0000071` +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00059" -#### Added -- [death stage](http://purl.obolibrary.org/obo/UBERON_0000071) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11200094" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [death stage](http://purl.obolibrary.org/obo/UBERON_0000071) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15984785" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [death stage](http://purl.obolibrary.org/obo/UBERON_0000071) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11798107" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [death stage](http://purl.obolibrary.org/obo/UBERON_0000071) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11581495" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- Class: [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) -### dental epithelium `http://purl.obolibrary.org/obo/UBERON_0003843` -#### Removed -- [dental epithelium](http://purl.obolibrary.org/obo/UBERON_0003843) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [cofactor](http://purl.obolibrary.org/obo/CHEBI_23357) -#### Added -- [dental epithelium](http://purl.obolibrary.org/obo/UBERON_0003843) SubClassOf [anatomical entity](http://purl.obolibrary.org/obo/CARO_0000000) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) SubClassOf [sulfur oxoanion](http://purl.obolibrary.org/obo/CHEBI_33482) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) -### dental pulp cell `http://purl.obolibrary.org/obo/CL_0002148` -#### Removed -- [dental pulp cell](http://purl.obolibrary.org/obo/CL_0002148) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000339"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) SubClassOf [divalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79388) -- [dental pulp cell](http://purl.obolibrary.org/obo/CL_0002148) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A cell found within the dental pulp."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tfm" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11087820"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) SubClassOf [sulfur oxide](http://purl.obolibrary.org/obo/CHEBI_48154) -#### Added -- [dental pulp cell](http://purl.obolibrary.org/obo/CL_0002148) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A cell found within the dental pulp."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tfm" +- [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:36267574"^^[string](http://www.w3.org/2001/XMLSchema#string) -### dental pulp stem cell `http://purl.obolibrary.org/obo/CL_4030035` +### sulfate binding `http://purl.obolibrary.org/obo/GO_0043199` +#### Removed +- [sulfate binding](http://purl.obolibrary.org/obo/GO_0043199) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" -#### Added -- [dental pulp stem cell](http://purl.obolibrary.org/obo/CL_4030035) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A dental pulp cell that possesses stem-cell-like qualities, including self-renewal capability and multi-lineage differentiation."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) [0000-0002-2825-0621](https://orcid.org/0000-0002-2825-0621) +- [sulfate binding](http://purl.obolibrary.org/obo/GO_0043199) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0043199" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DOI:10.1177/154405910208100806"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfate binding](http://purl.obolibrary.org/obo/GO_0043199) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to sulfate, SO4(2-), a negatively charged small molecule." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mlg" -- [dental pulp stem cell](http://purl.obolibrary.org/obo/CL_4030035) [date](http://purl.org/dc/terms/date) "2023-01-10T14:02:02Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) +- [sulfate binding](http://purl.obolibrary.org/obo/GO_0043199) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfate binding" -- [dental pulp stem cell](http://purl.obolibrary.org/obo/CL_4030035) [label](http://www.w3.org/2000/01/rdf-schema#label) "dental pulp stem cell" +- Class: [sulfate binding](http://purl.obolibrary.org/obo/GO_0043199) -- [dental pulp stem cell](http://purl.obolibrary.org/obo/CL_4030035) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "DPSC"^^[string](http://www.w3.org/2001/XMLSchema#string) - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [abbreviation](http://purl.obolibrary.org/obo/cl#abbreviation) +- [sulfate binding](http://purl.obolibrary.org/obo/GO_0043199) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189)) -- Class: [dental pulp stem cell](http://purl.obolibrary.org/obo/CL_4030035) +- [sulfate binding](http://purl.obolibrary.org/obo/GO_0043199) SubClassOf [anion binding](http://purl.obolibrary.org/obo/GO_0043168) -- [dental pulp stem cell](http://purl.obolibrary.org/obo/CL_4030035) EquivalentTo [stem cell](http://purl.obolibrary.org/obo/CL_0000034) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [dental pulp](http://purl.obolibrary.org/obo/UBERON_0001754)) +- [sulfate binding](http://purl.obolibrary.org/obo/GO_0043199) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) -- [dental pulp stem cell](http://purl.obolibrary.org/obo/CL_4030035) SubClassOf [stem cell](http://purl.obolibrary.org/obo/CL_0000034) +- [sulfate binding](http://purl.obolibrary.org/obo/GO_0043199) SubClassOf [sulfur compound binding](http://purl.obolibrary.org/obo/GO_1901681) -- [dental pulp stem cell](http://purl.obolibrary.org/obo/CL_4030035) SubClassOf [dental pulp cell](http://purl.obolibrary.org/obo/CL_0002148) -### dermal skeletal element `http://purl.obolibrary.org/obo/UBERON_0004756` +### sulfate ion homeostasis `http://purl.obolibrary.org/obo/GO_0055063` #### Removed -- [dermal skeletal element](http://purl.obolibrary.org/obo/UBERON_0004756) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055063) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfate homeostasis" +- [sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055063) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulphate ion homeostasis" +- [sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055063) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfate ion homeostasis" -### developing anatomical structure `http://purl.obolibrary.org/obo/UBERON_0005423` +- [sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055063) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0080174" -#### Added -- [developing anatomical structure](http://purl.obolibrary.org/obo/UBERON_0005423) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055063) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0055063" -- [developing anatomical structure](http://purl.obolibrary.org/obo/UBERON_0005423) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055063) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -- [developing anatomical structure](http://purl.obolibrary.org/obo/UBERON_0005423) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055063) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jid" -- [developing anatomical structure](http://purl.obolibrary.org/obo/UBERON_0005423) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" +- Class: [sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055063) -### disconnected anatomical group `http://purl.obolibrary.org/obo/UBERON_0034923` +- [sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055063) EquivalentTo [chemical homeostasis](http://purl.obolibrary.org/obo/GO_0048878) and ([regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189)) -#### Added -- [disconnected anatomical group](http://purl.obolibrary.org/obo/UBERON_0034923) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055063) SubClassOf [inorganic ion homeostasis](http://purl.obolibrary.org/obo/GO_0098771) -- [disconnected anatomical group](http://purl.obolibrary.org/obo/UBERON_0034923) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [sulfate ion homeostasis](http://purl.obolibrary.org/obo/GO_0055063) SubClassOf [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) -- [disconnected anatomical group](http://purl.obolibrary.org/obo/UBERON_0034923) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) -- [disconnected anatomical group](http://purl.obolibrary.org/obo/UBERON_0034923) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +### sulfate transmembrane transport `http://purl.obolibrary.org/obo/GO_1902358` +#### Removed +- [sulfate transmembrane transport](http://purl.obolibrary.org/obo/GO_1902358) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2013-08-14T14:46:04Z" -### dopaminergic neuron `http://purl.obolibrary.org/obo/CL_0000700` +- [sulfate transmembrane transport](http://purl.obolibrary.org/obo/GO_1902358) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfate transmembrane transport" -#### Added -- [dopaminergic neuron](http://purl.obolibrary.org/obo/CL_0000700) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005131"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfate transmembrane transport](http://purl.obolibrary.org/obo/GO_1902358) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" +- [sulfate transmembrane transport](http://purl.obolibrary.org/obo/GO_1902358) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of sulfate across a membrane." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9055073" -### early spermatid `http://purl.obolibrary.org/obo/CL_4030036` + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" -#### Added -- [early spermatid](http://purl.obolibrary.org/obo/CL_4030036) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "round spermatid"^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://doi.org/10.1016/B978-0-323-01970-5.50014-2"^^[string](http://www.w3.org/2001/XMLSchema#string) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" -- [early spermatid](http://purl.obolibrary.org/obo/CL_4030036) [label](http://www.w3.org/2000/01/rdf-schema#label) "early spermatid" +- [sulfate transmembrane transport](http://purl.obolibrary.org/obo/GO_1902358) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902358" -- [early spermatid](http://purl.obolibrary.org/obo/CL_4030036) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A spermatid in an early stage of maturation that has a round morphology and is transcriptionally active."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://www.proteinatlas.org/humanproteome/single+cell+type/Germ+cells#earlyspermatids"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfate transmembrane transport](http://purl.obolibrary.org/obo/GO_1902358) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "dph" -- [early spermatid](http://purl.obolibrary.org/obo/CL_4030036) [date](http://purl.org/dc/terms/date) "2023-02-01T13:56:00Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) +- Class: [sulfate transmembrane transport](http://purl.obolibrary.org/obo/GO_1902358) -- Class: [early spermatid](http://purl.obolibrary.org/obo/CL_4030036) +- [sulfate transmembrane transport](http://purl.obolibrary.org/obo/GO_1902358) EquivalentTo [transmembrane transport](http://purl.obolibrary.org/obo/GO_0055085) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189)) -- [early spermatid](http://purl.obolibrary.org/obo/CL_4030036) SubClassOf [capable of](http://purl.obolibrary.org/obo/RO_0002215) some [spermatid development](http://purl.obolibrary.org/obo/GO_0007286) +- [sulfate transmembrane transport](http://purl.obolibrary.org/obo/GO_1902358) SubClassOf [inorganic anion transmembrane transport](http://purl.obolibrary.org/obo/GO_0098661) -- [early spermatid](http://purl.obolibrary.org/obo/CL_4030036) SubClassOf [spermatid](http://purl.obolibrary.org/obo/CL_0000018) +- [sulfate transmembrane transport](http://purl.obolibrary.org/obo/GO_1902358) SubClassOf [sulfate transport](http://purl.obolibrary.org/obo/GO_0008272) -- [early spermatid](http://purl.obolibrary.org/obo/CL_4030036) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [male reproductive system](http://purl.obolibrary.org/obo/UBERON_0000079) -### effector T cell `http://purl.obolibrary.org/obo/CL_0000911` +### sulfate transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015116` #### Removed -- [effector T cell](http://purl.obolibrary.org/obo/CL_0000911) EquivalentTo [mature T cell](http://purl.obolibrary.org/obo/CL_0002419) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [normal life span](http://purl.obolibrary.org/obo/PATO_0045026)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) +- [sulfate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015116) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-8875871" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "SLC26A11 transports SO4(2-) from extracellular region to cytosol" -- [effector T cell](http://purl.obolibrary.org/obo/CL_0000911) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) +- [sulfate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015116) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "RHEA:34983" -#### Added -- [effector T cell](http://purl.obolibrary.org/obo/CL_0000911) EquivalentTo [mature T cell](http://purl.obolibrary.org/obo/CL_0002419) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [normal life span](http://purl.obolibrary.org/obo/PATO_0045026)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) +- [sulfate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015116) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulfate permease activity" -- [effector T cell](http://purl.obolibrary.org/obo/CL_0000911) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) +- [sulfate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015116) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfate transmembrane transporter activity" +- [sulfate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015116) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" -### effector memory CD4-positive, alpha-beta T cell, terminally differentiated `http://purl.obolibrary.org/obo/CL_0001087` -#### Removed -- [effector memory CD4-positive, alpha-beta T cell, terminally differentiated](http://purl.obolibrary.org/obo/CL_0001087) EquivalentTo [CD4-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000897) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) +- [sulfate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015116) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulphate transporter activity" -#### Added -- [effector memory CD4-positive, alpha-beta T cell, terminally differentiated](http://purl.obolibrary.org/obo/CL_0001087) EquivalentTo [CD4-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000897) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) +- [sulfate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015116) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-3560789" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "Defective SLC26A2 does not cotransport extracellular SO4(2-), H+ to cytosol" +- [sulfate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015116) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" -### effector memory CD8-positive, alpha-beta T cell, terminally differentiated `http://purl.obolibrary.org/obo/CL_0001062` -#### Removed -- [effector memory CD8-positive, alpha-beta T cell, terminally differentiated](http://purl.obolibrary.org/obo/CL_0001062) EquivalentTo [CD8-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000909) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) +- [sulfate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015116) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-427555" + - [label](http://www.w3.org/2000/01/rdf-schema#label) "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol" -#### Added -- [effector memory CD8-positive, alpha-beta T cell, terminally differentiated](http://purl.obolibrary.org/obo/CL_0001062) EquivalentTo [CD8-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000909) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([in taxon](http://purl.obolibrary.org/obo/RO_0002162) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RO](http://purl.obolibrary.org/obo/PR_000001017)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) +- [sulfate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015116) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0015116" +- Class: [sulfate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015116) -### efferent lymphatic vessel `http://purl.obolibrary.org/obo/UBERON_0010397` +- [sulfate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015116) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189)) -#### Added -- [efferent lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0010397) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Lymphatic vessel that exits the lymph node. The efferent lymphatic vessel commences from the lymph sinuses of the medullary portion of the lymph nodes and leave the lymph nodes either to veins or greater nodes. Efferent lymphatic vessels are also found in the thymus and spleen. This is in contrast to afferent lymphatic vessels, which are found only in lymph nodes." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MP:MP" +- [sulfate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015116) SubClassOf [sulfur compound transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901682) -- [efferent lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0010397) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MA:0000749" +- [sulfate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015116) SubClassOf [inorganic anion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015103) -- [efferent lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0010397) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "efferent lymphatic vessel" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Efferent_lymph_vessel" +- [sulfate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015116) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) -- [efferent lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0010397) [label](http://www.w3.org/2000/01/rdf-schema#label) "efferent lymphatic vessel" +- [sulfate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015116) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [sulfate transmembrane transport](http://purl.obolibrary.org/obo/GO_1902358) + - [source](http://www.geneontology.org/formats/oboInOwl#http://purl.org/dc/terms/source) "GO_REF:0000090" -- [efferent lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0010397) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [pheno_slim](http://purl.obolibrary.org/obo/uberon/core#pheno_slim) -- [efferent lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0010397) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0010397" -- [efferent lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0010397) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) +### sulfate transport `http://purl.obolibrary.org/obo/GO_0008272` +#### Removed +- [sulfate transport](http://purl.obolibrary.org/obo/GO_0008272) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0008272" -- [efferent lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0010397) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [sulfate transport](http://purl.obolibrary.org/obo/GO_0008272) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0006870" -- [efferent lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0010397) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Efferent_lymph_vessel" +- [sulfate transport](http://purl.obolibrary.org/obo/GO_0008272) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:krc" -- [efferent lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0010397) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) +- [sulfate transport](http://purl.obolibrary.org/obo/GO_0008272) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfate transport" -- [efferent lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0010397) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "efferent lymphatic vessels" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Efferent_lymph_vessel" +- [sulfate transport](http://purl.obolibrary.org/obo/GO_0008272) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulphate transport" -- Class: [efferent lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0010397) +- [sulfate transport](http://purl.obolibrary.org/obo/GO_0008272) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -- [efferent lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0010397) SubClassOf [lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0001473) +- Class: [sulfate transport](http://purl.obolibrary.org/obo/GO_0008272) +- [sulfate transport](http://purl.obolibrary.org/obo/GO_0008272) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189)) -### endometrial ciliated epithelial cell `http://purl.obolibrary.org/obo/CL_4030040` +- [sulfate transport](http://purl.obolibrary.org/obo/GO_0008272) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sulfate](http://purl.obolibrary.org/obo/CHEBI_16189) -#### Added -- [endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030040) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "endometrium ciliated epithelial cell"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfate transport](http://purl.obolibrary.org/obo/GO_0008272) SubClassOf [inorganic anion transport](http://purl.obolibrary.org/obo/GO_0015698) -- [endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030040) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A ciliated cell of the endometrial epithelium. The cilia of this cell type help move mucus from glandular tissue of the endometrium."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://www.proteinatlas.org/humanproteome/single+cell+type/Glandular+epithelial+cells#endometrialciliatedcells"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfate transport](http://purl.obolibrary.org/obo/GO_0008272) SubClassOf [sulfur compound transport](http://purl.obolibrary.org/obo/GO_0072348) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://www.nature.com/articles/s41591-020-1040-z"^^[string](http://www.w3.org/2001/XMLSchema#string) -- [endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030040) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "ciliated cell of the uterus"^^[string](http://www.w3.org/2001/XMLSchema#string) -- [endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030040) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "In human samples, the expression of FOXJ1 protein, a regulator for motile cilia with epithelial lineage identity, has been noted."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ttps://www.nature.com/articles/s41591-020-1040-z"^^[string](http://www.w3.org/2001/XMLSchema#string) +### sulfated glycosaminoglycan `http://purl.obolibrary.org/obo/CHEBI_35722` +#### Removed +- [sulfated glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_35722) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glycosaminoglycan sulfates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030040) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "uterine ciliated cell"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfated glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_35722) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulfated glycosaminoglycans" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030040) [date](http://purl.org/dc/terms/date) "2023-02-09T11:25:14Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) +- [sulfated glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_35722) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030040) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ciliated cell of the endometrium"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfated glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_35722) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfated glycosaminoglycan" -- [endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030040) [label](http://www.w3.org/2000/01/rdf-schema#label) "endometrial ciliated epithelial cell" +- [sulfated glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_35722) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35722" -- Class: [endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030040) +- [sulfated glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_35722) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030040) EquivalentTo [ciliated cell](http://purl.obolibrary.org/obo/CL_0000064) and [epithelial cell](http://purl.obolibrary.org/obo/CL_0000066) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [endometrium epithelium](http://purl.obolibrary.org/obo/UBERON_0004811)) +- [sulfated glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_35722) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glycosaminoglycan sulfate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030040) SubClassOf [ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_0000067) +- [sulfated glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_35722) SubClassOf [glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_18085) -- [endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030040) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [endometrium epithelium](http://purl.obolibrary.org/obo/UBERON_0004811) +- [sulfated glycosaminoglycan](http://purl.obolibrary.org/obo/CHEBI_35722) SubClassOf [carbohydrate sulfate](http://purl.obolibrary.org/obo/CHEBI_35724) -### endometrium luminal epithelium `http://purl.obolibrary.org/obo/UBERON_0011949` -#### Added -- [endometrium luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011949) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MA:0002733" +### sulfates `http://purl.obolibrary.org/obo/CHEBI_26820` +#### Removed +- [sulfates](http://purl.obolibrary.org/obo/CHEBI_26820) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [endometrium luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011949) [label](http://www.w3.org/2000/01/rdf-schema#label) "endometrium luminal epithelium" +- [sulfates](http://purl.obolibrary.org/obo/CHEBI_26820) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [endometrium luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011949) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0011949" +- [sulfates](http://purl.obolibrary.org/obo/CHEBI_26820) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulfuric acid derivative" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [endometrium luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011949) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) +- [sulfates](http://purl.obolibrary.org/obo/CHEBI_26820) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [endometrium luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011949) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [sulfates](http://purl.obolibrary.org/obo/CHEBI_26820) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulphates" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [endometrium luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011949) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) +- [sulfates](http://purl.obolibrary.org/obo/CHEBI_26820) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Salts and esters of sulfuric acid" -- [endometrium luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011949) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A luminal layer of epithelium that is part of a endometrium epithelium." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [sulfates](http://purl.obolibrary.org/obo/CHEBI_26820) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26820" -- [endometrium luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011949) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EMAPA:35309" +- [sulfates](http://purl.obolibrary.org/obo/CHEBI_26820) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfates" -- Class: [endometrium luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011949) +- Class: [sulfates](http://purl.obolibrary.org/obo/CHEBI_26820) -- [endometrium luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011949) EquivalentTo [luminal layer of epithelium](http://purl.obolibrary.org/obo/UBERON_0011945) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [endometrium epithelium](http://purl.obolibrary.org/obo/UBERON_0004811)) +- [sulfates](http://purl.obolibrary.org/obo/CHEBI_26820) SubClassOf [sulfuric acid derivative](http://purl.obolibrary.org/obo/CHEBI_37826) -- [endometrium luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011949) SubClassOf [luminal layer of epithelium](http://purl.obolibrary.org/obo/UBERON_0011945) -- [endometrium luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011949) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [endometrium epithelium](http://purl.obolibrary.org/obo/UBERON_0004811) +### sulfur atom `http://purl.obolibrary.org/obo/CHEBI_26833` +#### Removed +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "soufre" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -### endothelial cell of arteriole of lymph node `http://purl.obolibrary.org/obo/CL_4033001` +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [mass](http://purl.obolibrary.org/obo/chebi/mass) "32.06600" -#### Added -- [endothelial cell of arteriole of lymph node](http://purl.obolibrary.org/obo/CL_4033001) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A(n) endothelial cell that is part of a(n) arteriole of lymph node."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28217126" +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WebElements:S" -- [endothelial cell of arteriole of lymph node](http://purl.obolibrary.org/obo/CL_4033001) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7704-34-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" -- [endothelial cell of arteriole of lymph node](http://purl.obolibrary.org/obo/CL_4033001) [label](http://www.w3.org/2000/01/rdf-schema#label) "endothelial cell of arteriole of lymph node"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Elemental sulfur" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" -- Class: [endothelial cell of arteriole of lymph node](http://purl.obolibrary.org/obo/CL_4033001) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/S" -- [endothelial cell of arteriole of lymph node](http://purl.obolibrary.org/obo/CL_4033001) EquivalentTo [endothelial cell](http://purl.obolibrary.org/obo/CL_0000115) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [arteriole of lymph node](http://purl.obolibrary.org/obo/UBERON_8410042)) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00087" -- [endothelial cell of arteriole of lymph node](http://purl.obolibrary.org/obo/CL_4033001) SubClassOf [endothelial cell of arteriole](http://purl.obolibrary.org/obo/CL_1000412) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "azufre" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [endothelial cell of arteriole of lymph node](http://purl.obolibrary.org/obo/CL_4033001) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [arteriole of lymph node](http://purl.obolibrary.org/obo/UBERON_8410042) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7704-34-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Schwefel" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -### endothelial cell of efferent lymphatic vessel `http://purl.obolibrary.org/obo/CL_4033006` +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "S" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -#### Added -- [endothelial cell of efferent lymphatic vessel](http://purl.obolibrary.org/obo/CL_4033006) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfur" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [endothelial cell of efferent lymphatic vessel](http://purl.obolibrary.org/obo/CL_4033006) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A(n) endothelial cell that is part of a(n) efferent lymphatic vessel."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32094869"^^[string](http://www.w3.org/2001/XMLSchema#string) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [endothelial cell of efferent lymphatic vessel](http://purl.obolibrary.org/obo/CL_4033006) [label](http://www.w3.org/2000/01/rdf-schema#label) "endothelial cell of efferent lymphatic vessel"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "theion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- Class: [endothelial cell of efferent lymphatic vessel](http://purl.obolibrary.org/obo/CL_4033006) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [formula](http://purl.obolibrary.org/obo/chebi/formula) "S" -- [endothelial cell of efferent lymphatic vessel](http://purl.obolibrary.org/obo/CL_4033006) EquivalentTo [endothelial cell](http://purl.obolibrary.org/obo/CL_0000115) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [efferent lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0010397)) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [endothelial cell of efferent lymphatic vessel](http://purl.obolibrary.org/obo/CL_4033006) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [efferent lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0010397) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulphur" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [endothelial cell of efferent lymphatic vessel](http://purl.obolibrary.org/obo/CL_4033006) SubClassOf [endothelial cell](http://purl.obolibrary.org/obo/CL_0000115) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulfur" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfur atom" -### endothelial cell of venule of lymph node `http://purl.obolibrary.org/obo/CL_4033000` +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "NINIDFKCEFEMDL-UHFFFAOYSA-N" -#### Added -- [endothelial cell of venule of lymph node](http://purl.obolibrary.org/obo/CL_4033000) [label](http://www.w3.org/2000/01/rdf-schema#label) "endothelial cell of venule of lymph node"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulfur" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [endothelial cell of venule of lymph node](http://purl.obolibrary.org/obo/CL_4033000) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A(n) endothelial cell that is part of a(n) venule of lymph node."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28217126" +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [endothelial cell of venule of lymph node](http://purl.obolibrary.org/obo/CL_4033000) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "31.97207" -- Class: [endothelial cell of venule of lymph node](http://purl.obolibrary.org/obo/CL_4033000) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D06527" -- [endothelial cell of venule of lymph node](http://purl.obolibrary.org/obo/CL_4033000) EquivalentTo [endothelial cell](http://purl.obolibrary.org/obo/CL_0000115) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [venule of lymph node](http://purl.obolibrary.org/obo/UBERON_8410041)) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "S" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" -- [endothelial cell of venule of lymph node](http://purl.obolibrary.org/obo/CL_4033000) SubClassOf [endothelial cell](http://purl.obolibrary.org/obo/CL_0000115) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26833" -- [endothelial cell of venule of lymph node](http://purl.obolibrary.org/obo/CL_4033000) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [venule of lymph node](http://purl.obolibrary.org/obo/UBERON_8410041) +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "16S" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -### epithelium of bronchiole `http://purl.obolibrary.org/obo/UBERON_0002051` -#### Removed -- [epithelium of bronchiole](http://purl.obolibrary.org/obo/UBERON_0002051) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "epithelial tissue of lobular bronchiole" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PPDB:605" -- [epithelium of bronchiole](http://purl.obolibrary.org/obo/UBERON_0002051) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobular bronchiole epithelial tissue" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[S]" -- [epithelium of bronchiole](http://purl.obolibrary.org/obo/UBERON_0002051) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "epithelium of lobular bronchiole" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- Class: [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) -- [epithelium of bronchiole](http://purl.obolibrary.org/obo/UBERON_0002051) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62497" +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [macronutrient](http://purl.obolibrary.org/obo/CHEBI_33937) -- [epithelium of bronchiole](http://purl.obolibrary.org/obo/UBERON_0002051) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobular bronchiole epithelium" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) SubClassOf [nonmetal atom](http://purl.obolibrary.org/obo/CHEBI_25585) -- [epithelium of bronchiole](http://purl.obolibrary.org/obo/UBERON_0002051) [UBPROP_0000012](http://purl.obolibrary.org/obo/UBPROP_0000012) "in FMA2 and FMA3, lobular bronchiole is an exact synonym of bronchiole; however there are two distinct terms for the corresponding epithelium." - - [external_ontology](http://www.geneontology.org/formats/oboInOwl#external_ontology) "FMA" +- [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) SubClassOf [chalcogen](http://purl.obolibrary.org/obo/CHEBI_33303) -- [epithelium of bronchiole](http://purl.obolibrary.org/obo/UBERON_0002051) SubClassOf [epithelium of bronchus](http://purl.obolibrary.org/obo/UBERON_0002031) -#### Added -- [epithelium of bronchiole](http://purl.obolibrary.org/obo/UBERON_0002051) SubClassOf [tracheobronchial epithelium](http://purl.obolibrary.org/obo/UBERON_0008397) +### sulfur compound binding `http://purl.obolibrary.org/obo/GO_1901681` +#### Removed +- [sulfur compound binding](http://purl.obolibrary.org/obo/GO_1901681) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to a sulfur compound." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" -### epithelium of lobular bronchiole `http://purl.obolibrary.org/obo/UBERON_8600001` + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pr" -#### Added -- [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobular bronchiole epithelium" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62497" +- [sulfur compound binding](http://purl.obolibrary.org/obo/GO_1901681) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901681" -- [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001) [label](http://www.w3.org/2000/01/rdf-schema#label) "epithelium of lobular bronchiole" +- [sulfur compound binding](http://purl.obolibrary.org/obo/GO_1901681) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfur compound binding" -- [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "epithelium of preterminal bronchiole" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16543587" +- [sulfur compound binding](http://purl.obolibrary.org/obo/GO_1901681) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfur molecular entity binding" -- [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001) [date](http://purl.org/dc/terms/date) "2023-02-10T14:26:09Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) +- [sulfur compound binding](http://purl.obolibrary.org/obo/GO_1901681) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "pr" -- [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:8600001" +- [sulfur compound binding](http://purl.obolibrary.org/obo/GO_1901681) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" -- [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](http://orcid.org/0000-0001-6677-8489) +- [sulfur compound binding](http://purl.obolibrary.org/obo/GO_1901681) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-11-26T20:45:23Z" -- [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An epithelium of the lobular bronchiole." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62497" +- Class: [sulfur compound binding](http://purl.obolibrary.org/obo/GO_1901681) -- [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [sulfur compound binding](http://purl.obolibrary.org/obo/GO_1901681) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835)) -- Class: [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001) +- [sulfur compound binding](http://purl.obolibrary.org/obo/GO_1901681) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) -- [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001) EquivalentTo [epithelium](http://purl.obolibrary.org/obo/UBERON_0000483) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600000)) +- [sulfur compound binding](http://purl.obolibrary.org/obo/GO_1901681) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) -- [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600000) -- [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001) SubClassOf [epithelium of bronchiole](http://purl.obolibrary.org/obo/UBERON_0002051) +### sulfur compound biosynthetic process `http://purl.obolibrary.org/obo/GO_0044272` +#### Removed +- [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" -### esophagus smooth muscle circular layer `http://purl.obolibrary.org/obo/UBERON_0009960` +- [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "sulfur biosynthetic process" -#### Added -- [esophagus smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0009960) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EMAPA:37523" - - [source](http://www.geneontology.org/formats/oboInOwl#source) "MA:th" +- [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "sulfur biosynthesis" -- [esophagus smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0009960) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:67605" +- [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfur compound biosynthetic process" -- [esophagus smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0009960) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MA:0001574" +- [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfur compound anabolism" -- [esophagus smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0009960) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0044272" -- [esophagus smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0009960) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "esophagus smooth muscle circular layer" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MA:0001574" +- [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -- [esophagus smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0009960) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "inner circular muscle layer of esophagus" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:67605" +- [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfur compound biosynthesis" -- [esophagus smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0009960) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A circular muscle layer of muscular coat that is part of a esophagus." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfur compound synthesis" -- [esophagus smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0009960) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0009960" +- [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfur compound formation" -- [esophagus smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0009960) [label](http://www.w3.org/2000/01/rdf-schema#label) "esophagus smooth muscle circular layer" +- Class: [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) -- [esophagus smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0009960) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "circular muscle layer of esophagus" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:67605" +- [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835)) -- Class: [esophagus smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0009960) +- [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) -- [esophagus smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0009960) EquivalentTo [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [esophagus](http://purl.obolibrary.org/obo/UBERON_0001043)) +- [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) SubClassOf [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) -- [esophagus smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0009960) SubClassOf [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) +- [sulfur compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044272) SubClassOf [cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0044249) -- [esophagus smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0009960) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [smooth muscle of esophagus](http://purl.obolibrary.org/obo/UBERON_0002112) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "MA" -### external carotid artery `http://purl.obolibrary.org/obo/UBERON_0001070` +### sulfur compound catabolic process `http://purl.obolibrary.org/obo/GO_0044273` #### Removed -- [external carotid artery](http://purl.obolibrary.org/obo/UBERON_0001070) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [sulfur compound catabolic process](http://purl.obolibrary.org/obo/GO_0044273) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfur compound catabolic process" +- [sulfur compound catabolic process](http://purl.obolibrary.org/obo/GO_0044273) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" +- [sulfur compound catabolic process](http://purl.obolibrary.org/obo/GO_0044273) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfur compound breakdown" -### facial muscle `http://purl.obolibrary.org/obo/UBERON_0001577` -#### Removed -- [facial muscle](http://purl.obolibrary.org/obo/UBERON_0001577) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) - +- [sulfur compound catabolic process](http://purl.obolibrary.org/obo/GO_0044273) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "sulfur catabolism" +- [sulfur compound catabolic process](http://purl.obolibrary.org/obo/GO_0044273) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfur compound catabolism" -### flight muscle cell `http://purl.obolibrary.org/obo/CL_0000196` +- [sulfur compound catabolic process](http://purl.obolibrary.org/obo/GO_0044273) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfur compound degradation" -#### Added -- [flight muscle cell](http://purl.obolibrary.org/obo/CL_0000196) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00003360"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfur compound catabolic process](http://purl.obolibrary.org/obo/GO_0044273) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0044273" +- [sulfur compound catabolic process](http://purl.obolibrary.org/obo/GO_0044273) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" -### future internal carotid artery `http://purl.obolibrary.org/obo/UBERON_2001053` -#### Removed -- [future internal carotid artery](http://purl.obolibrary.org/obo/UBERON_2001053) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [sulfur compound catabolic process](http://purl.obolibrary.org/obo/GO_0044273) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "sulfur catabolic process" +- Class: [sulfur compound catabolic process](http://purl.obolibrary.org/obo/GO_0044273) +- [sulfur compound catabolic process](http://purl.obolibrary.org/obo/GO_0044273) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835)) -### glandular endometrial ciliated epithelial cell `http://purl.obolibrary.org/obo/CL_4030042` +- [sulfur compound catabolic process](http://purl.obolibrary.org/obo/GO_0044273) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) -#### Added -- [glandular endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030042) [label](http://www.w3.org/2000/01/rdf-schema#label) "glandular endometrial ciliated epithelial cell" +- [sulfur compound catabolic process](http://purl.obolibrary.org/obo/GO_0044273) SubClassOf [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) -- [glandular endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030042) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A ciliated cell of the endometrial glandular epithelium."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://www.nature.com/articles/s41591-020-1040-z"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfur compound catabolic process](http://purl.obolibrary.org/obo/GO_0044273) SubClassOf [cellular catabolic process](http://purl.obolibrary.org/obo/GO_0044248) -- [glandular endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030042) [date](http://purl.org/dc/terms/date) "2023-02-09T11:37:30Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) -- Class: [glandular endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030042) -- [glandular endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030042) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [endometrium glandular epithelium](http://purl.obolibrary.org/obo/UBERON_0012276) +### sulfur compound metabolic process `http://purl.obolibrary.org/obo/GO_0006790` +#### Removed +- [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_drosophila](http://purl.obolibrary.org/obo/go#goslim_drosophila) -- [glandular endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030042) SubClassOf [endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030040) +- [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_pir](http://purl.obolibrary.org/obo/go#goslim_pir) +- [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006790" -### glutamatergic neuron `http://purl.obolibrary.org/obo/CL_0000679` +- [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sulfur_metabolism" -#### Added -- [glutamatergic neuron](http://purl.obolibrary.org/obo/CL_0000679) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A neuron that is capable of some neurotansmission by glutamate secretion." +- [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_chembl](http://purl.obolibrary.org/obo/go#goslim_chembl) -- [glutamatergic neuron](http://purl.obolibrary.org/obo/CL_0000679) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00100291"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulphur metabolic process" +- [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -### glycinergic neuron `http://purl.obolibrary.org/obo/CL_1001509` +- [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulphur metabolism" -#### Added -- [glycinergic neuron](http://purl.obolibrary.org/obo/CL_1001509) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00048032"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfur metabolism" +- [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" -### goblet cell of epithelium of lobar bronchus `http://purl.obolibrary.org/obo/CL_4033009` +- [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) -#### Added -- [goblet cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033009) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A(n) goblet cell that is part of a(n) epithelium of lobar bronchus."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18757316"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfur compound metabolic process" -- [goblet cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033009) [label](http://www.w3.org/2000/01/rdf-schema#label) "goblet cell of epithelium of lobar bronchus"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_pombe](http://purl.obolibrary.org/obo/go#goslim_pombe) -- [goblet cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033009) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) +- [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_generic](http://purl.obolibrary.org/obo/go#goslim_generic) -- Class: [goblet cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033009) +- Class: [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) -- [goblet cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033009) EquivalentTo [goblet cell](http://purl.obolibrary.org/obo/CL_0000160) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of lobar bronchus](http://purl.obolibrary.org/obo/UBERON_0002339)) +- [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835)) -- [goblet cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033009) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of lobar bronchus](http://purl.obolibrary.org/obo/UBERON_0002339) +- [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) -- [goblet cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033009) SubClassOf [lung goblet cell](http://purl.obolibrary.org/obo/CL_1000143) +- [sulfur compound metabolic process](http://purl.obolibrary.org/obo/GO_0006790) SubClassOf [cellular metabolic process](http://purl.obolibrary.org/obo/GO_0044237) -- [goblet cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033009) SubClassOf [bronchial goblet cell](http://purl.obolibrary.org/obo/CL_1000312) -### gonadotropin releasing neuron `http://purl.obolibrary.org/obo/CL_0011111` +### sulfur compound transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_1901682` #### Removed -- [gonadotropin releasing neuron](http://purl.obolibrary.org/obo/CL_0011111) SubClassOf [neurosecretory neuron](http://purl.obolibrary.org/obo/CL_0000381) +- [sulfur compound transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901682) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2012-11-26T20:45:29Z" -- [gonadotropin releasing neuron](http://purl.obolibrary.org/obo/CL_0011111) SubClassOf [endocrine cell](http://purl.obolibrary.org/obo/CL_0000163) +- [sulfur compound transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901682) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" -#### Added -- [gonadotropin releasing neuron](http://purl.obolibrary.org/obo/CL_0011111) SubClassOf [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) +- [sulfur compound transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901682) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfur molecular entity transmembrane transporter activity" +- [sulfur compound transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901682) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1901682" -### gonadtroph `http://purl.obolibrary.org/obo/CL_0000437` +- [sulfur compound transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901682) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "pr" -#### Added -- [gonadtroph](http://purl.obolibrary.org/obo/CL_0000437) SubClassOf [gonadotropin releasing neuron](http://purl.obolibrary.org/obo/CL_0011111) +- [sulfur compound transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901682) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfur compound transmembrane transporter activity" +- [sulfur compound transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901682) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of a sulfur compound from one side of a membrane to the other." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" -### hair follicle `http://purl.obolibrary.org/obo/UBERON_0002073` -#### Removed -- [hair follicle](http://purl.obolibrary.org/obo/UBERON_0002073) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pr" +- Class: [sulfur compound transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901682) +- [sulfur compound transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901682) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835)) -### has developmental contribution from `http://purl.obolibrary.org/obo/RO_0002254` -#### Removed -- Transitive: [has developmental contribution from](http://purl.obolibrary.org/obo/RO_0002254) +- [sulfur compound transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901682) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + +- [sulfur compound transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_1901682) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) -### has_completed `http://purl.obolibrary.org/obo/cl#has_completed` +### sulfur compound transport `http://purl.obolibrary.org/obo/GO_0072348` #### Removed -- [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) [label](http://www.w3.org/2000/01/rdf-schema#label) "has_completed"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfur compound transport](http://purl.obolibrary.org/obo/GO_0072348) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfur compound transport" -- ObjectProperty: [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) +- [sulfur compound transport](http://purl.obolibrary.org/obo/GO_0072348) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" +- [sulfur compound transport](http://purl.obolibrary.org/obo/GO_0072348) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-11-11T11:43:56Z" +- [sulfur compound transport](http://purl.obolibrary.org/obo/GO_0072348) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0072348" -### hindbrain `http://purl.obolibrary.org/obo/UBERON_0002028` -#### Removed -- [hindbrain](http://purl.obolibrary.org/obo/UBERON_0002028) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [sulfur compound transport](http://purl.obolibrary.org/obo/GO_0072348) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfur-containing compound transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" +- [sulfur compound transport](http://purl.obolibrary.org/obo/GO_0072348) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" +- [sulfur compound transport](http://purl.obolibrary.org/obo/GO_0072348) [created_by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" -### hindbrain neural plate `http://purl.obolibrary.org/obo/UBERON_0009614` -#### Removed -- [hindbrain neural plate](http://purl.obolibrary.org/obo/UBERON_0009614) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- Class: [sulfur compound transport](http://purl.obolibrary.org/obo/GO_0072348) +- [sulfur compound transport](http://purl.obolibrary.org/obo/GO_0072348) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835)) +- [sulfur compound transport](http://purl.obolibrary.org/obo/GO_0072348) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) -### histaminergic neuron `http://purl.obolibrary.org/obo/CL_0011110` +- [sulfur compound transport](http://purl.obolibrary.org/obo/GO_0072348) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) -#### Added -- [histaminergic neuron](http://purl.obolibrary.org/obo/CL_0011110) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007367"^^[string](http://www.w3.org/2001/XMLSchema#string) -### hyoid arch skeleton `http://purl.obolibrary.org/obo/UBERON_0005884` +### sulfur molecular entity `http://purl.obolibrary.org/obo/CHEBI_26835` #### Removed -- [hyoid arch skeleton](http://purl.obolibrary.org/obo/UBERON_0005884) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) - -#### Added -- [hyoid arch skeleton](http://purl.obolibrary.org/obo/UBERON_0005884) SubClassOf [anatomical entity](http://purl.obolibrary.org/obo/CARO_0000000) +- [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" +- [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -### hyoid bone `http://purl.obolibrary.org/obo/UBERON_0001685` -#### Removed -- [hyoid bone](http://purl.obolibrary.org/obo/UBERON_0001685) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26835" +- [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfur molecular entity" +- [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulfur molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -### imaginal disc cell `http://purl.obolibrary.org/obo/CL_0000429` +- [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfur molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -#### Added -- [imaginal disc cell](http://purl.obolibrary.org/obo/CL_0000429) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007108"^^[string](http://www.w3.org/2001/XMLSchema#string) +- Class: [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) +- [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) SubClassOf [chalcogen molecular entity](http://purl.obolibrary.org/obo/CHEBI_33304) -### immaterial anatomical entity `http://purl.obolibrary.org/obo/UBERON_0000466` +- [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [sulfur atom](http://purl.obolibrary.org/obo/CHEBI_26833) -#### Added -- [immaterial anatomical entity](http://purl.obolibrary.org/obo/UBERON_0000466) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) -- [immaterial anatomical entity](http://purl.obolibrary.org/obo/UBERON_0000466) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) -- [immaterial anatomical entity](http://purl.obolibrary.org/obo/UBERON_0000466) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +### sulfur oxide `http://purl.obolibrary.org/obo/CHEBI_48154` +#### Removed +- [sulfur oxide](http://purl.obolibrary.org/obo/CHEBI_48154) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfur oxide" -- [immaterial anatomical entity](http://purl.obolibrary.org/obo/UBERON_0000466) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [sulfur oxide](http://purl.obolibrary.org/obo/CHEBI_48154) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxides of sulfur" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" +- [sulfur oxide](http://purl.obolibrary.org/obo/CHEBI_48154) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -### internal carotid artery `http://purl.obolibrary.org/obo/UBERON_0001532` -#### Removed -- [internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0001532) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [sulfur oxide](http://purl.obolibrary.org/obo/CHEBI_48154) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulfur oxides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" +- [sulfur oxide](http://purl.obolibrary.org/obo/CHEBI_48154) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Schwefeloxide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" +- [sulfur oxide](http://purl.obolibrary.org/obo/CHEBI_48154) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -### iridophore `http://purl.obolibrary.org/obo/CL_0000431` -#### Removed -- [iridophore](http://purl.obolibrary.org/obo/CL_0000431) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A pigment cell derived from the neural crest. The cell contains flat light-reflecting platelets, probably of guanine, in stacks called reflecting platets or iridisomes. The color-generating components produce a silver, gold, or iridescent color."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "SANBI:mhl"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfur oxide](http://purl.obolibrary.org/obo/CHEBI_48154) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:48154" -#### Added -- [iridophore](http://purl.obolibrary.org/obo/CL_0000431) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A pigment cell derived from the neural crest. The cell contains flat light-reflecting platelets, probably of guanine, in stacks called reflecting platelets or iridisomes. The color-generating components produce a silver, gold, or iridescent color."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "SANBI:mhl"^^[string](http://www.w3.org/2001/XMLSchema#string) +- Class: [sulfur oxide](http://purl.obolibrary.org/obo/CHEBI_48154) +- [sulfur oxide](http://purl.obolibrary.org/obo/CHEBI_48154) SubClassOf [inorganic oxide](http://purl.obolibrary.org/obo/CHEBI_24836) -### juvenile hormone secreting cell `http://purl.obolibrary.org/obo/CL_0000482` +- [sulfur oxide](http://purl.obolibrary.org/obo/CHEBI_48154) SubClassOf [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) -#### Added -- [juvenile hormone secreting cell](http://purl.obolibrary.org/obo/CL_0000482) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00058020"^^[string](http://www.w3.org/2001/XMLSchema#string) -### kidney inner medulla collecting duct epithelial cell `http://purl.obolibrary.org/obo/CL_1000547` +### sulfur oxoacid `http://purl.obolibrary.org/obo/CHEBI_33402` +#### Removed +- [sulfur oxoacid](http://purl.obolibrary.org/obo/CHEBI_33402) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxoacids of sulfur" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -#### Added -- [kidney inner medulla collecting duct epithelial cell](http://purl.obolibrary.org/obo/CL_1000547) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An epithelial cell that is part of some inner medullary collecting duct." +- [sulfur oxoacid](http://purl.obolibrary.org/obo/CHEBI_33402) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfur oxoacid" +- [sulfur oxoacid](http://purl.obolibrary.org/obo/CHEBI_33402) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -### kidney loop of Henle cortical thick ascending limb epithelial cell `http://purl.obolibrary.org/obo/CL_1001109` +- [sulfur oxoacid](http://purl.obolibrary.org/obo/CHEBI_33402) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -#### Added -- [kidney loop of Henle cortical thick ascending limb epithelial cell](http://purl.obolibrary.org/obo/CL_1001109) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An epithelial cell that is part of some loop of Henle thick ascending limb segment located in the renal cortex." +- [sulfur oxoacid](http://purl.obolibrary.org/obo/CHEBI_33402) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33402" +- [sulfur oxoacid](http://purl.obolibrary.org/obo/CHEBI_33402) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulfur oxoacids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -### kidney loop of Henle medullary thick ascending limb epithelial cell `http://purl.obolibrary.org/obo/CL_1001108` +- Class: [sulfur oxoacid](http://purl.obolibrary.org/obo/CHEBI_33402) -#### Added -- [kidney loop of Henle medullary thick ascending limb epithelial cell](http://purl.obolibrary.org/obo/CL_1001108) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An epithelial cell that is part of some loop of Henle thick ascending limb segment located in the renal medulla." +- [sulfur oxoacid](http://purl.obolibrary.org/obo/CHEBI_33402) SubClassOf [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) +- [sulfur oxoacid](http://purl.obolibrary.org/obo/CHEBI_33402) SubClassOf [chalcogen oxoacid](http://purl.obolibrary.org/obo/CHEBI_33484) -### kidney loop of Henle thick ascending limb epithelial cell `http://purl.obolibrary.org/obo/CL_1001106` -#### Added -- [kidney loop of Henle thick ascending limb epithelial cell](http://purl.obolibrary.org/obo/CL_1001106) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An epithelial cell that is part of some loop of Henle thick ascending limb. It is known in some mammalian species that this cell may express the Na+-K+-2Cl− cotransporter (NKCC2) apically." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25318757"^^[string](http://www.w3.org/2001/XMLSchema#string) +### sulfur oxoacid derivative `http://purl.obolibrary.org/obo/CHEBI_33424` +#### Removed +- [sulfur oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33424) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -### kidney loop of Henle thin ascending limb epithelial cell `http://purl.obolibrary.org/obo/CL_1001107` +- [sulfur oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33424) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33424" -#### Added -- [kidney loop of Henle thin ascending limb epithelial cell](http://purl.obolibrary.org/obo/CL_1001107) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An epithelial cell that is part of some loop of Henle thin ascending limb." +- [sulfur oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33424) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" +- [sulfur oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33424) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulfur oxoacid derivatives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -### kidney loop of Henle thin descending limb epithelial cell `http://purl.obolibrary.org/obo/CL_1001111` +- [sulfur oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33424) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfur oxoacid derivative" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -#### Added -- [kidney loop of Henle thin descending limb epithelial cell](http://purl.obolibrary.org/obo/CL_1001111) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An epithelial cell that is part of some loop of Henle thin descending limb." +- [sulfur oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33424) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfur oxoacid derivative" +- Class: [sulfur oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33424) -### kidney outer medulla collecting duct intercalated cell `http://purl.obolibrary.org/obo/CL_1000717` +- [sulfur oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33424) SubClassOf [oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33241) -#### Added -- [kidney outer medulla collecting duct intercalated cell](http://purl.obolibrary.org/obo/CL_1000717) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Intercalated cell that is part of some outer medullary collecting duct. It is known in some mammalian species that this cell may contribute in the maintenance of acid/base homeostasis." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25632105"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfur oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33424) SubClassOf [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) -### kidney outer medulla collecting duct principal cell `http://purl.obolibrary.org/obo/CL_1000716` -#### Added -- [kidney outer medulla collecting duct principal cell](http://purl.obolibrary.org/obo/CL_1000716) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Principal cell that is part of some outer medullary collecting duct. It is known in some mammalian species that this cell may express the epithelial sodium channel (ENaC)." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25632105"^^[string](http://www.w3.org/2001/XMLSchema#string) +### sulfur oxoanion `http://purl.obolibrary.org/obo/CHEBI_33482` +#### Removed +- [sulfur oxoanion](http://purl.obolibrary.org/obo/CHEBI_33482) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulfur oxoanions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" +- [sulfur oxoanion](http://purl.obolibrary.org/obo/CHEBI_33482) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33482" -### kidney resident macrophage `http://purl.obolibrary.org/obo/CL_1000698` +- [sulfur oxoanion](http://purl.obolibrary.org/obo/CHEBI_33482) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "oxoanions of sulfur" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -#### Added -- [kidney resident macrophage](http://purl.obolibrary.org/obo/CL_1000698) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A tissue-resident macrophage that is part of some kidney." +- [sulfur oxoanion](http://purl.obolibrary.org/obo/CHEBI_33482) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" +- [sulfur oxoanion](http://purl.obolibrary.org/obo/CHEBI_33482) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -### large intestine smooth muscle circular layer `http://purl.obolibrary.org/obo/UBERON_0012398` +- [sulfur oxoanion](http://purl.obolibrary.org/obo/CHEBI_33482) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfur oxoanion" -#### Added -- [large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012398) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MA:0001548" +- [sulfur oxoanion](http://purl.obolibrary.org/obo/CHEBI_33482) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfur oxoanion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012398) [label](http://www.w3.org/2000/01/rdf-schema#label) "large intestine smooth muscle circular layer" +- Class: [sulfur oxoanion](http://purl.obolibrary.org/obo/CHEBI_33482) -- [large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012398) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EMAPA:37558" - - [source](http://www.geneontology.org/formats/oboInOwl#source) "MA:th" +- [sulfur oxoanion](http://purl.obolibrary.org/obo/CHEBI_33482) SubClassOf [sulfur molecular entity](http://purl.obolibrary.org/obo/CHEBI_26835) -- [large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012398) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "circular muscle layer of segment of large intestine" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:81160" +- [sulfur oxoanion](http://purl.obolibrary.org/obo/CHEBI_33482) SubClassOf [chalcogen oxoanion](http://purl.obolibrary.org/obo/CHEBI_33485) -- [large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012398) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) -- [large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012398) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:81160" -- [large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012398) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A circular muscle layer of muscular coat that is part of a large intestine smooth muscle." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +### sulfuric acid `http://purl.obolibrary.org/obo/CHEBI_26836` +#### Removed +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogen tetraoxosulfate(2-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012398) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0012398" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012398) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sulfuric_acid" -- [large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012398) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22136045" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- Class: [large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012398) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012398) EquivalentTo [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [large intestine smooth muscle](http://purl.obolibrary.org/obo/UBERON_0004220)) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00007530" -- [large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012398) SubClassOf [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:2037554" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" -- [large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012398) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [large intestine smooth muscle](http://purl.obolibrary.org/obo/UBERON_0004220) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22047659" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Schwefelsaeureloesungen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" -### large intestine smooth muscle longitudinal layer `http://purl.obolibrary.org/obo/UBERON_0012399` +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfuric acid" -#### Added -- [large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012399) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A longitudinal muscle layer of muscular coat that is part of a large intestine smooth muscle." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D05963" -- [large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012399) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7664-93-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" -- [large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012399) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EMAPA:37559" - - [source](http://www.geneontology.org/formats/oboInOwl#source) "MA:th" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetraoxosulfuric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012399) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "longitudinal muscle layer of zone of large intestine" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:63637" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012399) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Acide sulfurique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" -- [large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012399) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0012399" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" -- [large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012399) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Acido sulfurico" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" -- [large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012399) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MA:0001549" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:13568755" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012399) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:63637" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19397353" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012399) [label](http://www.w3.org/2000/01/rdf-schema#label) "large intestine smooth muscle longitudinal layer" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22204399" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- Class: [large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012399) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22296037" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012399) EquivalentTo [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [large intestine smooth muscle](http://purl.obolibrary.org/obo/UBERON_0004220)) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00059" -- [large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012399) SubClassOf [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16122922" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012399) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [large intestine smooth muscle](http://purl.obolibrary.org/obo/UBERON_0004220) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7664-93-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "QAOWNCQODCNURD-UHFFFAOYSA-N" -### laryngeal apparatus `http://purl.obolibrary.org/obo/UBERON_0010212` -#### Removed -- [laryngeal apparatus](http://purl.obolibrary.org/obo/UBERON_0010212) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26836" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfuric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -### laryngeal associated mesenchyme `http://purl.obolibrary.org/obo/UBERON_0010221` -#### Removed -- [laryngeal associated mesenchyme](http://purl.obolibrary.org/obo/UBERON_0010221) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PPDB:606" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [formula](http://purl.obolibrary.org/obo/chebi/formula) "H2O4S" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22267186" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -### laryngeal pre-cartilage condensation `http://purl.obolibrary.org/obo/UBERON_0010213` -#### Removed -- [laryngeal pre-cartilage condensation](http://purl.obolibrary.org/obo/UBERON_0010213) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dihydrogen tetraoxosulfate" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:2122" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" -### late spermatid `http://purl.obolibrary.org/obo/CL_4030037` +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [mass](http://purl.obolibrary.org/obo/chebi/mass) "98.07948" -#### Added -- [late spermatid](http://purl.obolibrary.org/obo/CL_4030037) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "elongated spermatid"^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://doi.org/10.1016/B978-0-323-01970-5.50014-2"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[SO2(OH)2]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [late spermatid](http://purl.obolibrary.org/obo/CL_4030037) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A spermatid in a late stage of maturation that has an elongated morphology and is transcriptionally inert when the acrosome is fully developed."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://www.proteinatlas.org/humanproteome/single+cell+type/Germ+cells#latespermatids"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MolBase:4" -- [late spermatid](http://purl.obolibrary.org/obo/CL_4030037) [label](http://www.w3.org/2000/01/rdf-schema#label) "late spermatid" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "97.96738" -- [late spermatid](http://purl.obolibrary.org/obo/CL_4030037) [date](http://purl.org/dc/terms/date) "2023-02-01T14:02:15Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfuric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- Class: [late spermatid](http://purl.obolibrary.org/obo/CL_4030037) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [late spermatid](http://purl.obolibrary.org/obo/CL_4030037) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [male reproductive system](http://purl.obolibrary.org/obo/UBERON_0000079) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Sulfuric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" -- [late spermatid](http://purl.obolibrary.org/obo/CL_4030037) SubClassOf [capable of](http://purl.obolibrary.org/obo/RO_0002215) some [spermatid development](http://purl.obolibrary.org/obo/GO_0007286) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7664-93-9" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" -- [late spermatid](http://purl.obolibrary.org/obo/CL_4030037) SubClassOf [spermatid](http://purl.obolibrary.org/obo/CL_0000018) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom." -- [late spermatid](http://purl.obolibrary.org/obo/CL_4030037) SubClassOf [develops from](http://purl.obolibrary.org/obo/RO_0002202) some [early spermatid](http://purl.obolibrary.org/obo/CL_4030036) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[S(OH)2O2]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MolBase" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hydrogen tetraoxosulfate(VI)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -### left lung bronchiole `http://purl.obolibrary.org/obo/UBERON_0003539` -#### Removed -- [left lung bronchiole](http://purl.obolibrary.org/obo/UBERON_0003539) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobular bronchiole of left lung" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [left lung bronchiole](http://purl.obolibrary.org/obo/UBERON_0003539) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "left lung lobular bronchiole" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H]OS(=O)(=O)O[H]" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dihydroxidodioxidosulfur" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -### life cycle `http://purl.obolibrary.org/obo/UBERON_0000104` +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -#### Added -- [life cycle](http://purl.obolibrary.org/obo/UBERON_0000104) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "H2SO4" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [life cycle](http://purl.obolibrary.org/obo/UBERON_0000104) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Acidum sulfuricum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" -- [life cycle](http://purl.obolibrary.org/obo/UBERON_0000104) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22435616" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [life cycle](http://purl.obolibrary.org/obo/UBERON_0000104) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulphuric acid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MolBase" +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22364556" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -### life cycle stage `http://purl.obolibrary.org/obo/UBERON_0000105` +- Class: [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) -#### Added -- [life cycle stage](http://purl.obolibrary.org/obo/UBERON_0000105) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [catalyst](http://purl.obolibrary.org/obo/CHEBI_35223) -- [life cycle stage](http://purl.obolibrary.org/obo/UBERON_0000105) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) SubClassOf [sulfur oxoacid](http://purl.obolibrary.org/obo/CHEBI_33402) -- [life cycle stage](http://purl.obolibrary.org/obo/UBERON_0000105) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [hydrogensulfate](http://purl.obolibrary.org/obo/CHEBI_45696) -- [life cycle stage](http://purl.obolibrary.org/obo/UBERON_0000105) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) -### lingual swellings `http://purl.obolibrary.org/obo/UBERON_0006260` +### sulfuric acid derivative `http://purl.obolibrary.org/obo/CHEBI_37826` #### Removed -- [lingual swellings](http://purl.obolibrary.org/obo/UBERON_0006260) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) - -#### Added -- [lingual swellings](http://purl.obolibrary.org/obo/UBERON_0006260) SubClassOf [anatomical entity](http://purl.obolibrary.org/obo/CARO_0000000) +- [sulfuric acid derivative](http://purl.obolibrary.org/obo/CHEBI_37826) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) +- [sulfuric acid derivative](http://purl.obolibrary.org/obo/CHEBI_37826) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulfuric acid derivatives" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -### lobular bronchiole `http://purl.obolibrary.org/obo/UBERON_8600000` +- [sulfuric acid derivative](http://purl.obolibrary.org/obo/CHEBI_37826) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfuric acid derivative" -#### Added -- [lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600000) [date](http://purl.org/dc/terms/date) "2023-02-08T13:31:12Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) +- [sulfuric acid derivative](http://purl.obolibrary.org/obo/CHEBI_37826) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600000) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A conductive airway that branches into terminal bronchioles." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16543587" +- [sulfuric acid derivative](http://purl.obolibrary.org/obo/CHEBI_37826) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:37826" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:27611890" +- [sulfuric acid derivative](http://purl.obolibrary.org/obo/CHEBI_37826) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulfuric acid derivative" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600000) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](http://orcid.org/0000-0001-6677-8489) +- Class: [sulfuric acid derivative](http://purl.obolibrary.org/obo/CHEBI_37826) -- [lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600000) [label](http://www.w3.org/2000/01/rdf-schema#label) "lobular bronchiole" +- [sulfuric acid derivative](http://purl.obolibrary.org/obo/CHEBI_37826) SubClassOf [has_functional_parent](http://purl.obolibrary.org/obo/chebi#has_functional_parent) some [sulfuric acid](http://purl.obolibrary.org/obo/CHEBI_26836) -- [lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600000) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [sulfuric acid derivative](http://purl.obolibrary.org/obo/CHEBI_37826) SubClassOf [sulfur oxoacid derivative](http://purl.obolibrary.org/obo/CHEBI_33424) -- [lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600000) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "preterminal bronchiole" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16543587" -- [lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600000) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:8600000" -- Class: [lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600000) +### sulfuric ester `http://purl.obolibrary.org/obo/CHEBI_26819` +#### Removed +- [sulfuric ester](http://purl.obolibrary.org/obo/CHEBI_26819) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26819" -- [lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600000) SubClassOf [bronchiole](http://purl.obolibrary.org/obo/UBERON_0002186) +- [sulfuric ester](http://purl.obolibrary.org/obo/CHEBI_26819) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulfate ester" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" +- [sulfuric ester](http://purl.obolibrary.org/obo/CHEBI_26819) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "95.95173" -### longitudinal muscle layer of muscular coat `http://purl.obolibrary.org/obo/UBERON_0012369` +- [sulfuric ester](http://purl.obolibrary.org/obo/CHEBI_26819) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -#### Added -- [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0005214" +- [sulfuric ester](http://purl.obolibrary.org/obo/CHEBI_26819) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[*]OS(=O)(=O)O[*]" -- [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62900" +- [sulfuric ester](http://purl.obolibrary.org/obo/CHEBI_26819) [mass](http://purl.obolibrary.org/obo/chebi/mass) "96.06300" -- [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "outer muscularis" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62900" +- [sulfuric ester](http://purl.obolibrary.org/obo/CHEBI_26819) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "longitudinal muscle layer" +- [sulfuric ester](http://purl.obolibrary.org/obo/CHEBI_26819) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulfuric acid esters" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "outer muscularis layer" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62900" +- [sulfuric ester](http://purl.obolibrary.org/obo/CHEBI_26819) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" -- [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) [label](http://www.w3.org/2000/01/rdf-schema#label) "longitudinal muscle layer of muscular coat" +- [sulfuric ester](http://purl.obolibrary.org/obo/CHEBI_26819) [label](http://www.w3.org/2000/01/rdf-schema#label) "sulfuric ester" -- [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [sulfuric ester](http://purl.obolibrary.org/obo/CHEBI_26819) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulfuric acid ester" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The outer layer of the muscular coat." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0005214" +- [sulfuric ester](http://purl.obolibrary.org/obo/CHEBI_26819) [formula](http://purl.obolibrary.org/obo/chebi/formula) "O4SR2" -- [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0012369" +- [sulfuric ester](http://purl.obolibrary.org/obo/CHEBI_26819) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An ester of an alcohol and sulfuric acid." -- [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "longitudinal smooth muscle" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0005214" +- Class: [sulfuric ester](http://purl.obolibrary.org/obo/CHEBI_26819) -- Class: [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) +- [sulfuric ester](http://purl.obolibrary.org/obo/CHEBI_26819) SubClassOf [sulfuric acid derivative](http://purl.obolibrary.org/obo/CHEBI_37826) -- [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) SubClassOf [layer of smooth muscle tissue](http://purl.obolibrary.org/obo/UBERON_0034933) +- [sulfuric ester](http://purl.obolibrary.org/obo/CHEBI_26819) SubClassOf [ester](http://purl.obolibrary.org/obo/CHEBI_35701) -- [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [muscular coat](http://purl.obolibrary.org/obo/UBERON_0006660) -### luminal endometrial ciliated epithelial cell `http://purl.obolibrary.org/obo/CL_4030041` +### superior paraolivary nucleus `http://purl.obolibrary.org/obo/UBERON_8440043` +#### Removed +- [superior paraolivary nucleus](http://purl.obolibrary.org/obo/UBERON_8440043) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-7258-9596](http://orcid.org/0000-0001-7258-9596) #### Added -- [luminal endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030041) [label](http://www.w3.org/2000/01/rdf-schema#label) "luminal endometrial ciliated epithelial cell"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [superior paraolivary nucleus](http://purl.obolibrary.org/obo/UBERON_8440043) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-7258-9596](https://orcid.org/0000-0001-7258-9596) -- [luminal endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030041) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A ciliated cell of the endometrial luminal epithelium."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://www.nature.com/articles/s41591-020-1040-z"^^[string](http://www.w3.org/2001/XMLSchema#string) -- [luminal endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030041) [date](http://purl.org/dc/terms/date) "2023-02-09T11:34:42Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) - -- Class: [luminal endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030041) - -- [luminal endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030041) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [endometrium luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011949) +### superoxide `http://purl.obolibrary.org/obo/CHEBI_18421` +#### Removed +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23542447" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [luminal endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030041) SubClassOf [endometrial ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_4030040) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11008114" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dioxide(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -### luminal layer of epithelium `http://purl.obolibrary.org/obo/UBERON_0011945` +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:33248264" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -#### Added -- [luminal layer of epithelium](http://purl.obolibrary.org/obo/UBERON_0011945) [label](http://www.w3.org/2000/01/rdf-schema#label) "luminal layer of epithelium" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Superoxide anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" -- [luminal layer of epithelium](http://purl.obolibrary.org/obo/UBERON_0011945) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0002168" -- [luminal layer of epithelium](http://purl.obolibrary.org/obo/UBERON_0011945) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0011945" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "OUUQCZGPVNCOIJ-UHFFFAOYSA-M" -- Class: [luminal layer of epithelium](http://purl.obolibrary.org/obo/UBERON_0011945) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30500433" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [luminal layer of epithelium](http://purl.obolibrary.org/obo/UBERON_0011945) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium](http://purl.obolibrary.org/obo/UBERON_0000483) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9337481" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [luminal layer of epithelium](http://purl.obolibrary.org/obo/UBERON_0011945) SubClassOf [multi cell part structure](http://purl.obolibrary.org/obo/UBERON_0005162) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "O2.-" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17303648" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -### lung ciliated cell `http://purl.obolibrary.org/obo/CL_1000271` -#### Removed -- [lung ciliated cell](http://purl.obolibrary.org/obo/CL_1000271) SubClassOf [ciliated cell](http://purl.obolibrary.org/obo/CL_0000064) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "superoxide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [lung ciliated cell](http://purl.obolibrary.org/obo/CL_1000271) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -#### Added -- [lung ciliated cell](http://purl.obolibrary.org/obo/CL_1000271) SubClassOf [respiratory ciliated cell](http://purl.obolibrary.org/obo/CL_4030034) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28842493" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:26875845" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -### magnocellular neurosecretory cell `http://purl.obolibrary.org/obo/CL_0011003` -#### Removed -- [magnocellular neurosecretory cell](http://purl.obolibrary.org/obo/CL_0011003) SubClassOf [anatomical entity](http://purl.obolibrary.org/obo/CARO_0000000) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15807660" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [magnocellular neurosecretory cell](http://purl.obolibrary.org/obo/CL_0011003) SubClassOf [neurosecretory neuron](http://purl.obolibrary.org/obo/CL_0000381) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:2FK" -#### Added -- [magnocellular neurosecretory cell](http://purl.obolibrary.org/obo/CL_0011003) SubClassOf [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19628033" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22247596" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -### mammary gland luminal epithelium `http://purl.obolibrary.org/obo/UBERON_0011950` +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21434856" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -#### Added -- [mammary gland luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011950) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The inner cell layer of the mammary epithelium bilayer that lines the luminal surface of mammary gland ducts and alveoli; luminal cells have only limited contact with the underlying basement membrane and surrounding connective tissue; they are secretory epithelial cells characterized by the expression of the receptors for systemic hormones, i.e. estrogens, progesterone and prolactin." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MGI:anna" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19273321" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [mammary gland luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011950) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lumina layer of epithelium of lactiferous gland" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74458" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10588368" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [mammary gland luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011950) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EMAPA:37902" - - [source](http://www.geneontology.org/formats/oboInOwl#source) "MA:th" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:33805942" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [mammary gland luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011950) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74458" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "31.98983" -- [mammary gland luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011950) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0011950" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28842347" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [mammary gland luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011950) [label](http://www.w3.org/2000/01/rdf-schema#label) "mammary gland luminal epithelium" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:26047895" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [mammary gland luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011950) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dioxide(.1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- Class: [mammary gland luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011950) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [mammary gland luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011950) EquivalentTo [luminal layer of epithelium](http://purl.obolibrary.org/obo/UBERON_0011945) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [mammary gland](http://purl.obolibrary.org/obo/UBERON_0001911)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24862271" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [mammary gland luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011950) SubClassOf [luminal layer of epithelium](http://purl.obolibrary.org/obo/UBERON_0011945) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "superoxide radical" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [mammary gland luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011950) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of mammary gland](http://purl.obolibrary.org/obo/UBERON_0003244) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hiperoxido" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" - - [is_inferred](http://www.geneontology.org/formats/oboInOwl#is_inferred) "true" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "superoxide anion radical" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "superoxyde" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -### material anatomical entity `http://purl.obolibrary.org/obo/UBERON_0000465` +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:29896077" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -#### Added -- [material anatomical entity](http://purl.obolibrary.org/obo/UBERON_0000465) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:7710" -- [material anatomical entity](http://purl.obolibrary.org/obo/UBERON_0000465) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30573187" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [material anatomical entity](http://purl.obolibrary.org/obo/UBERON_0000465) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FooDB:FDB022880" -- [material anatomical entity](http://purl.obolibrary.org/obo/UBERON_0000465) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:27590268" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Dioxid(1-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -### mature B cell `http://purl.obolibrary.org/obo/CL_0000785` -#### Removed -- [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) EquivalentTo [B cell, CD19-positive](http://purl.obolibrary.org/obo/CL_0001201) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [antigen processing and presentation of peptide or polysaccharide antigen via MHC class II](http://purl.obolibrary.org/obo/GO_0002504)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [B cell activation](http://purl.obolibrary.org/obo/GO_0042113)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [mature B cell differentiation](http://purl.obolibrary.org/obo/GO_0002335)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18519744" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [mature B cell differentiation](http://purl.obolibrary.org/obo/GO_0002335) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32478084" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -#### Added -- [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) EquivalentTo [B cell, CD19-positive](http://purl.obolibrary.org/obo/CL_0001201) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [antigen processing and presentation of peptide or polysaccharide antigen via MHC class II](http://purl.obolibrary.org/obo/GO_0002504)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [B cell activation](http://purl.obolibrary.org/obo/GO_0042113)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [mature B cell differentiation](http://purl.obolibrary.org/obo/GO_0002335)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22521482" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [mature B cell differentiation](http://purl.obolibrary.org/obo/GO_0002335) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [label](http://www.w3.org/2000/01/rdf-schema#label) "superoxide" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15586010" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -### mature NK T cell `http://purl.obolibrary.org/obo/CL_0000814` -#### Removed -- [mature NK T cell](http://purl.obolibrary.org/obo/CL_0000814) EquivalentTo [mature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000791) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [MHC class Ib receptor activity](http://purl.obolibrary.org/obo/GO_0032394)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [innate immune response](http://purl.obolibrary.org/obo/GO_0045087)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Hyperoxid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [mature NK T cell](http://purl.obolibrary.org/obo/CL_0000814) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22198225" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -#### Added -- [mature NK T cell](http://purl.obolibrary.org/obo/CL_0000814) EquivalentTo [mature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000791) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [KLRB1-like protein](http://purl.obolibrary.org/obo/PR_000001874)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [MHC class Ib receptor activity](http://purl.obolibrary.org/obo/GO_0032394)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [innate immune response](http://purl.obolibrary.org/obo/GO_0045087)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hyperoxide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [mature NK T cell](http://purl.obolibrary.org/obo/CL_0000814) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:27066179" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21297912" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -### mature T cell `http://purl.obolibrary.org/obo/CL_0002419` -#### Removed -- [mature T cell](http://purl.obolibrary.org/obo/CL_0002419) EquivalentTo [T cell](http://purl.obolibrary.org/obo/CL_0000084) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [T cell receptor complex](http://purl.obolibrary.org/obo/GO_0042101)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:33716500" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [mature T cell](http://purl.obolibrary.org/obo/CL_0002419) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -#### Added -- [mature T cell](http://purl.obolibrary.org/obo/CL_0002419) EquivalentTo [T cell](http://purl.obolibrary.org/obo/CL_0000084) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [T cell receptor complex](http://purl.obolibrary.org/obo/GO_0042101)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "O2(-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [mature T cell](http://purl.obolibrary.org/obo/CL_0002419) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19482633" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:31484901" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -### mature alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000791` -#### Removed -- [mature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000791) EquivalentTo [alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000789) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:487" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" -#### Added -- [mature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000791) EquivalentTo [alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000789) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superoxide" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:8577306" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -### mature gamma-delta T cell `http://purl.obolibrary.org/obo/CL_0000800` -#### Removed -- [mature gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000800) EquivalentTo [gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000798) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17531522" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -#### Added -- [mature gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000800) EquivalentTo [gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000798) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:14726604" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "superoxido" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -### maxillary artery `http://purl.obolibrary.org/obo/UBERON_0001616` -#### Removed -- [maxillary artery](http://purl.obolibrary.org/obo/UBERON_0001616) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [mass](http://purl.obolibrary.org/obo/chebi/mass) "31.999" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32220789" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17052238" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -### melanin biosynthetic process `http://purl.obolibrary.org/obo/GO_0042438` -#### Removed -- [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:curators" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:14703794" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) [label](http://www.w3.org/2000/01/rdf-schema#label) "melanin biosynthetic process" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:15143" -- [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "melanin synthesis" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Chemspider:4514331" -- [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "melanin anabolism" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [charge](http://purl.obolibrary.org/obo/chebi/charge) "-1" -- [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "melanin formation" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23660153" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32144830" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "melanin biosynthesis" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18827931" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0042438" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:27085844" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- Class: [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "(O2)(.-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [melanins](http://purl.obolibrary.org/obo/CHEBI_25179)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:14529453" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) SubClassOf [pigment biosynthetic process](http://purl.obolibrary.org/obo/GO_0046148) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10523323" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) SubClassOf [phenol-containing compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0046189) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16814528" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) SubClassOf [secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_0044550) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [formula](http://purl.obolibrary.org/obo/chebi/formula) "O2" -- [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [melanins](http://purl.obolibrary.org/obo/CHEBI_25179) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:31254369" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) SubClassOf [melanin metabolic process](http://purl.obolibrary.org/obo/GO_0006582) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10440226" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22759590" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:26839" -### melanin catabolic process `http://purl.obolibrary.org/obo/GO_0046150` -#### Removed -- [melanin catabolic process](http://purl.obolibrary.org/obo/GO_0046150) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:27965593" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin catabolic process](http://purl.obolibrary.org/obo/GO_0046150) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "melanin breakdown" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "O2-" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" -- [melanin catabolic process](http://purl.obolibrary.org/obo/GO_0046150) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "melanin catabolism" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32760286" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin catabolic process](http://purl.obolibrary.org/obo/GO_0046150) [label](http://www.w3.org/2000/01/rdf-schema#label) "melanin catabolic process" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:34635271" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin catabolic process](http://purl.obolibrary.org/obo/GO_0046150) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046150" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:2160451" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin catabolic process](http://purl.obolibrary.org/obo/GO_0046150) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00704" -- [melanin catabolic process](http://purl.obolibrary.org/obo/GO_0046150) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "melanin degradation" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:29259135" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- Class: [melanin catabolic process](http://purl.obolibrary.org/obo/GO_0046150) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12137408" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin catabolic process](http://purl.obolibrary.org/obo/GO_0046150) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [melanins](http://purl.obolibrary.org/obo/CHEBI_25179)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19914407" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin catabolic process](http://purl.obolibrary.org/obo/GO_0046150) SubClassOf [pigment catabolic process](http://purl.obolibrary.org/obo/GO_0046149) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28825637" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin catabolic process](http://purl.obolibrary.org/obo/GO_0046150) SubClassOf [phenol-containing compound catabolic process](http://purl.obolibrary.org/obo/GO_0019336) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12598407" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin catabolic process](http://purl.obolibrary.org/obo/GO_0046150) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [melanins](http://purl.obolibrary.org/obo/CHEBI_25179) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:1671684" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin catabolic process](http://purl.obolibrary.org/obo/GO_0046150) SubClassOf [melanin metabolic process](http://purl.obolibrary.org/obo/GO_0006582) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30307099" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19857607" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22729857" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -### melanin metabolic process `http://purl.obolibrary.org/obo/GO_0006582` -#### Removed -- [melanin metabolic process](http://purl.obolibrary.org/obo/GO_0006582) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:18421" -- [melanin metabolic process](http://purl.obolibrary.org/obo/GO_0006582) [label](http://www.w3.org/2000/01/rdf-schema#label) "melanin metabolic process" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:11062-77-4" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" -- [melanin metabolic process](http://purl.obolibrary.org/obo/GO_0006582) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20868230" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin metabolic process](http://purl.obolibrary.org/obo/GO_0006582) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "melanin metabolism" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:7998676" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin metabolic process](http://purl.obolibrary.org/obo/GO_0006582) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006582" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "superoxide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" -- Class: [melanin metabolic process](http://purl.obolibrary.org/obo/GO_0006582) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:2552230" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin metabolic process](http://purl.obolibrary.org/obo/GO_0006582) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [melanins](http://purl.obolibrary.org/obo/CHEBI_25179)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:29669742" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin metabolic process](http://purl.obolibrary.org/obo/GO_0006582) SubClassOf [phenol-containing compound metabolic process](http://purl.obolibrary.org/obo/GO_0018958) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15952898" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin metabolic process](http://purl.obolibrary.org/obo/GO_0006582) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [melanins](http://purl.obolibrary.org/obo/CHEBI_25179) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:27066025" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin metabolic process](http://purl.obolibrary.org/obo/GO_0006582) SubClassOf [secondary metabolic process](http://purl.obolibrary.org/obo/GO_0019748) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24567847" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanin metabolic process](http://purl.obolibrary.org/obo/GO_0006582) SubClassOf [pigment metabolic process](http://purl.obolibrary.org/obo/GO_0042440) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:8959373" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:29385710" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "superoxide radical anion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -### melanins `http://purl.obolibrary.org/obo/CHEBI_25179` -#### Removed -- [melanins](http://purl.obolibrary.org/obo/CHEBI_25179) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#1_STAR) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21473702" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanins](http://purl.obolibrary.org/obo/CHEBI_25179) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:6727" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32667121" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanins](http://purl.obolibrary.org/obo/CHEBI_25179) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:25179" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12097818" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanins](http://purl.obolibrary.org/obo/CHEBI_25179) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11333112" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanins](http://purl.obolibrary.org/obo/CHEBI_25179) [label](http://www.w3.org/2000/01/rdf-schema#label) "melanins" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23668959" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- Class: [melanins](http://purl.obolibrary.org/obo/CHEBI_25179) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:11062-77-4" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" -- [melanins](http://purl.obolibrary.org/obo/CHEBI_25179) SubClassOf [polyphenol](http://purl.obolibrary.org/obo/CHEBI_26195) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dioxidanidyl" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [melanins](http://purl.obolibrary.org/obo/CHEBI_25179) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [biological pigment](http://purl.obolibrary.org/obo/CHEBI_26130) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11485972" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:27357008" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -### melanophage `http://purl.obolibrary.org/obo/CL_0002060` -#### Removed -- [melanophage](http://purl.obolibrary.org/obo/CL_0002060) EquivalentTo [tissue-resident macrophage](http://purl.obolibrary.org/obo/CL_0000864) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [skin of body](http://purl.obolibrary.org/obo/UBERON_0002097)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [melanins](http://purl.obolibrary.org/obo/CHEBI_25179)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:217531" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [melanophage](http://purl.obolibrary.org/obo/CL_0002060) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [melanins](http://purl.obolibrary.org/obo/CHEBI_25179) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:SUPER-OXIDE" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/HO2/c1-2/h1H/p-1" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "O2(.-)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -### memory B cell `http://purl.obolibrary.org/obo/CL_0000787` -#### Removed -- [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [B cell affinity maturation](http://purl.obolibrary.org/obo/GO_0002344)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [syndecan-1](http://purl.obolibrary.org/obo/PR_000001935)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28599858" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [B cell affinity maturation](http://purl.obolibrary.org/obo/GO_0002344) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:8720916" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -#### Added -- [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) EquivalentTo [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [MHC class II protein complex](http://purl.obolibrary.org/obo/GO_0042613)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [B cell affinity maturation](http://purl.obolibrary.org/obo/GO_0002344)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [syndecan-1](http://purl.obolibrary.org/obo/PR_000001935)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16771675" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [B cell affinity maturation](http://purl.obolibrary.org/obo/GO_0002344) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:32927603" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28341974" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -### memory T cell `http://purl.obolibrary.org/obo/CL_0000813` -#### Removed -- [memory T cell](http://purl.obolibrary.org/obo/CL_0000813) EquivalentTo [mature T cell](http://purl.obolibrary.org/obo/CL_0002419) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [increased life span](http://purl.obolibrary.org/obo/PATO_0001603)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell activation involved in immune response](http://purl.obolibrary.org/obo/GO_0002286)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30886134" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [memory T cell](http://purl.obolibrary.org/obo/CL_0000813) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[O][O-]" -#### Added -- [memory T cell](http://purl.obolibrary.org/obo/CL_0000813) EquivalentTo [mature T cell](http://purl.obolibrary.org/obo/CL_0002419) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [increased life span](http://purl.obolibrary.org/obo/PATO_0001603)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell activation involved in immune response](http://purl.obolibrary.org/obo/GO_0002286)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:26475962" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [memory T cell](http://purl.obolibrary.org/obo/CL_0000813) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) SubClassOf [diatomic oxygen](http://purl.obolibrary.org/obo/CHEBI_33263) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) SubClassOf [inorganic radical anion](http://purl.obolibrary.org/obo/CHEBI_36876) -### memory regulatory T cell `http://purl.obolibrary.org/obo/CL_0002678` -#### Removed -- [memory regulatory T cell](http://purl.obolibrary.org/obo/CL_0002678) EquivalentTo [CD4-positive, CD25-positive, alpha-beta regulatory T cell](http://purl.obolibrary.org/obo/CL_0000792) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) -#### Added -- [memory regulatory T cell](http://purl.obolibrary.org/obo/CL_0002678) EquivalentTo [CD4-positive, CD25-positive, alpha-beta regulatory T cell](http://purl.obolibrary.org/obo/CL_0000792) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [memory T cell differentiation](http://purl.obolibrary.org/obo/GO_0043379)) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) SubClassOf [oxygen radical](http://purl.obolibrary.org/obo/CHEBI_61073) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) -### meninx of hindbrain `http://purl.obolibrary.org/obo/UBERON_0003291` -#### Removed -- [meninx of hindbrain](http://purl.obolibrary.org/obo/UBERON_0003291) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [superoxide](http://purl.obolibrary.org/obo/CHEBI_18421) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) -### mesenchyme of trachea `http://purl.obolibrary.org/obo/UBERON_0009505` +### superoxide metabolic process `http://purl.obolibrary.org/obo/GO_0006801` #### Removed -- [mesenchyme of trachea](http://purl.obolibrary.org/obo/UBERON_0009505) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [superoxide metabolic process](http://purl.obolibrary.org/obo/GO_0006801) SubClassOf [reactive oxygen species metabolic process](http://purl.obolibrary.org/obo/GO_0072593) +#### Added +- [superoxide metabolic process](http://purl.obolibrary.org/obo/GO_0006801) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) -### metencephalon `http://purl.obolibrary.org/obo/UBERON_0001895` +### surrounded by `http://purl.obolibrary.org/obo/RO_0002219` #### Removed -- [metencephalon](http://purl.obolibrary.org/obo/UBERON_0001895) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) - - - -### morphological feature `http://purl.obolibrary.org/obo/UBERON_0034768` +- [surrounded by](http://purl.obolibrary.org/obo/RO_0002219) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" #### Added -- [morphological feature](http://purl.obolibrary.org/obo/UBERON_0034768) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [surrounded by](http://purl.obolibrary.org/obo/RO_0002219) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) -- [morphological feature](http://purl.obolibrary.org/obo/UBERON_0034768) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) -- [morphological feature](http://purl.obolibrary.org/obo/UBERON_0034768) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +### surrounds `http://purl.obolibrary.org/obo/RO_0002221` +#### Removed +- [surrounds](http://purl.obolibrary.org/obo/RO_0002221) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" -- [morphological feature](http://purl.obolibrary.org/obo/UBERON_0034768) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +#### Added +- [surrounds](http://purl.obolibrary.org/obo/RO_0002221) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) -### mucosa of bronchiole `http://purl.obolibrary.org/obo/UBERON_0005039` +### sympathomimetic agent `http://purl.obolibrary.org/obo/CHEBI_35524` #### Removed -- [mucosa of bronchiole](http://purl.obolibrary.org/obo/UBERON_0005039) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobular bronchiole mucous membrane" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [sympathomimetic agent](http://purl.obolibrary.org/obo/CHEBI_35524) [label](http://www.w3.org/2000/01/rdf-schema#label) "sympathomimetic agent" -- [mucosa of bronchiole](http://purl.obolibrary.org/obo/UBERON_0005039) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "mucosa of organ of lobular bronchiole" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [sympathomimetic agent](http://purl.obolibrary.org/obo/CHEBI_35524) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [mucosa of bronchiole](http://purl.obolibrary.org/obo/UBERON_0005039) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "mucosa of lobular bronchiole" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [sympathomimetic agent](http://purl.obolibrary.org/obo/CHEBI_35524) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sympathomimetics" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [mucosa of bronchiole](http://purl.obolibrary.org/obo/UBERON_0005039) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organ mucosa of lobular bronchiole" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [sympathomimetic agent](http://purl.obolibrary.org/obo/CHEBI_35524) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters." -- [mucosa of bronchiole](http://purl.obolibrary.org/obo/UBERON_0005039) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobular bronchiole mucosa" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [sympathomimetic agent](http://purl.obolibrary.org/obo/CHEBI_35524) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sympathomimetic" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [mucosa of bronchiole](http://purl.obolibrary.org/obo/UBERON_0005039) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobular bronchiole organ mucosa" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [sympathomimetic agent](http://purl.obolibrary.org/obo/CHEBI_35524) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [mucosa of bronchiole](http://purl.obolibrary.org/obo/UBERON_0005039) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobular bronchiole mucosa of organ" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [sympathomimetic agent](http://purl.obolibrary.org/obo/CHEBI_35524) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35524" -- [mucosa of bronchiole](http://purl.obolibrary.org/obo/UBERON_0005039) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:263230" +- Class: [sympathomimetic agent](http://purl.obolibrary.org/obo/CHEBI_35524) -- [mucosa of bronchiole](http://purl.obolibrary.org/obo/UBERON_0005039) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "mucous membrane of lobular bronchiole" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [sympathomimetic agent](http://purl.obolibrary.org/obo/CHEBI_35524) SubClassOf [adrenergic agent](http://purl.obolibrary.org/obo/CHEBI_37962) -- [mucosa of bronchiole](http://purl.obolibrary.org/obo/UBERON_0005039) SubClassOf [bronchial mucosa](http://purl.obolibrary.org/obo/UBERON_0000410) -#### Added -- [mucosa of bronchiole](http://purl.obolibrary.org/obo/UBERON_0005039) SubClassOf [tracheal mucosa](http://purl.obolibrary.org/obo/UBERON_0000379) +### synapsed by `http://purl.obolibrary.org/obo/RO_0002103` +#### Removed +- [synapsed by](http://purl.obolibrary.org/obo/RO_0002103) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall"@en + +- [synapsed by](http://purl.obolibrary.org/obo/RO_0002103) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Relation between an anatomical structure and a neuron that chemically synapses to it." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBC:DOS" -### mucosa of lobular bronchiole `http://purl.obolibrary.org/obo/UBERON_8600002` +- [synapsed by](http://purl.obolibrary.org/obo/RO_0002103) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland"@en #### Added -- [mucosa of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600002) [label](http://www.w3.org/2000/01/rdf-schema#label) "mucosa of lobular bronchiole" +- [synapsed by](http://purl.obolibrary.org/obo/RO_0002103) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) -- [mucosa of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600002) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:8600002" +- [synapsed by](http://purl.obolibrary.org/obo/RO_0002103) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Relation between an anatomical structure and a neuron that chemically synapses to it." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) -- [mucosa of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600002) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [synapsed by](http://purl.obolibrary.org/obo/RO_0002103) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) -- [mucosa of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600002) [date](http://purl.org/dc/terms/date) "2023-02-10T14:48:35Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) -- [mucosa of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600002) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](http://orcid.org/0000-0001-6677-8489) +### synapsed to `http://purl.obolibrary.org/obo/RO_0002120` +#### Removed +- [synapsed to](http://purl.obolibrary.org/obo/RO_0002120) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Relation between a neuron and an anatomical structure that it chemically synapses to." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBC:DOS" -- [mucosa of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600002) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A mucosa that is part of a lobular bronchiole." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:263230" +- [synapsed to](http://purl.obolibrary.org/obo/RO_0002120) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "David Osumi-Sutherland"@en -- Class: [mucosa of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600002) +- [synapsed to](http://purl.obolibrary.org/obo/RO_0002120) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall"@en -- [mucosa of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600002) EquivalentTo [mucosa](http://purl.obolibrary.org/obo/UBERON_0000344) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600000)) +#### Added +- [synapsed to](http://purl.obolibrary.org/obo/RO_0002120) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) -- [mucosa of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600002) SubClassOf [mucosa of bronchiole](http://purl.obolibrary.org/obo/UBERON_0005039) +- [synapsed to](http://purl.obolibrary.org/obo/RO_0002120) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) -- [mucosa of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600002) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600000) +- [synapsed to](http://purl.obolibrary.org/obo/RO_0002120) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Relation between a neuron and an anatomical structure that it chemically synapses to." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) [0000-0002-7073-9172](https://orcid.org/0000-0002-7073-9172) -### mucosal invariant T cell `http://purl.obolibrary.org/obo/CL_0000940` +### system `http://purl.obolibrary.org/obo/RO_0002577` #### Removed -- [mucosal invariant T cell](http://purl.obolibrary.org/obo/CL_0000940) EquivalentTo [mature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000791) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [innate immune response in mucosa](http://purl.obolibrary.org/obo/GO_0002227)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [MHC class Ib receptor activity](http://purl.obolibrary.org/obo/GO_0032394)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) - -- [mucosal invariant T cell](http://purl.obolibrary.org/obo/CL_0000940) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) - -#### Added -- [mucosal invariant T cell](http://purl.obolibrary.org/obo/CL_0000940) EquivalentTo [mature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000791) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [innate immune response in mucosa](http://purl.obolibrary.org/obo/GO_0002227)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [MHC class Ib receptor activity](http://purl.obolibrary.org/obo/GO_0032394)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217)) - -- [mucosal invariant T cell](http://purl.obolibrary.org/obo/CL_0000940) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell differentiation](http://purl.obolibrary.org/obo/GO_0030217) - - -### multi organ part structure `http://purl.obolibrary.org/obo/UBERON_0034921` +- [system](http://purl.obolibrary.org/obo/RO_0002577) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" #### Added -- [multi organ part structure](http://purl.obolibrary.org/obo/UBERON_0034921) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [system](http://purl.obolibrary.org/obo/RO_0002577) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) -- [multi organ part structure](http://purl.obolibrary.org/obo/UBERON_0034921) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) -- [multi organ part structure](http://purl.obolibrary.org/obo/UBERON_0034921) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +### tanycyte `http://purl.obolibrary.org/obo/CL_0002085` +#### Removed +- [tanycyte](http://purl.obolibrary.org/obo/CL_0002085) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000643" -- [multi organ part structure](http://purl.obolibrary.org/obo/UBERON_0034921) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) -### multi-ciliated epithelial cell `http://purl.obolibrary.org/obo/CL_0005012` +### temporally related to `http://purl.obolibrary.org/obo/RO_0002222` #### Removed -- [multi-ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_0005012) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A ciliated epithelial cell with many cilium."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CL:CVS"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [temporally related to](http://purl.obolibrary.org/obo/RO_0002222) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" #### Added -- [multi-ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_0005012) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A ciliated epithelial cell with many cilia."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CL:CVS"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [temporally related to](http://purl.obolibrary.org/obo/RO_0002222) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) -### multi-tissue structure `http://purl.obolibrary.org/obo/UBERON_0000481` - -#### Added -- [multi-tissue structure](http://purl.obolibrary.org/obo/UBERON_0000481) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +### terpene `http://purl.obolibrary.org/obo/CHEBI_35186` +#### Removed +- [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH2=C(CH3)CH=CH2]." -- [multi-tissue structure](http://purl.obolibrary.org/obo/UBERON_0000481) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Terpen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [multi-tissue structure](http://purl.obolibrary.org/obo/UBERON_0000481) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) [label](http://www.w3.org/2000/01/rdf-schema#label) "terpene" -- [multi-tissue structure](http://purl.obolibrary.org/obo/UBERON_0000481) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "terpenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" +- [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "terpenos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -### multicellular anatomical structure `http://purl.obolibrary.org/obo/UBERON_0010000` +- [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35186" -#### Added -- [multicellular anatomical structure](http://purl.obolibrary.org/obo/UBERON_0010000) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [multicellular anatomical structure](http://purl.obolibrary.org/obo/UBERON_0010000) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [multicellular anatomical structure](http://purl.obolibrary.org/obo/UBERON_0010000) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "terpeno" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [multicellular anatomical structure](http://purl.obolibrary.org/obo/UBERON_0010000) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) +- [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -### multicellular organism `http://purl.obolibrary.org/obo/UBERON_0000468` +- [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpene" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -#### Added -- [multicellular organism](http://purl.obolibrary.org/obo/UBERON_0000468) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- Class: [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) -- [multicellular organism](http://purl.obolibrary.org/obo/UBERON_0000468) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) SubClassOf [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) -- [multicellular organism](http://purl.obolibrary.org/obo/UBERON_0000468) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) SubClassOf [hydrocarbon](http://purl.obolibrary.org/obo/CHEBI_24632) -- [multicellular organism](http://purl.obolibrary.org/obo/UBERON_0000468) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) -### myelencephalon `http://purl.obolibrary.org/obo/UBERON_0005290` +### terpene biosynthetic process `http://purl.obolibrary.org/obo/GO_0046246` #### Removed -- [myelencephalon](http://purl.obolibrary.org/obo/UBERON_0005290) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [terpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0046246) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of terpenes, any of a large group of hydrocarbons made up of isoprene units." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" +- [terpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0046246) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpene formation" +- [terpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0046246) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -### myoepithelial cell of bronchus submucosal gland `http://purl.obolibrary.org/obo/CL_4033003` - -#### Added -- [myoepithelial cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033003) [label](http://www.w3.org/2000/01/rdf-schema#label) "myoepithelial cell of bronchus submucosal gland"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0046246) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpene biosynthesis" -- [myoepithelial cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033003) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) +- [terpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0046246) [label](http://www.w3.org/2000/01/rdf-schema#label) "terpene biosynthetic process" -- [myoepithelial cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033003) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A(n) myoepithelial cell that is part of a(n) bronchus submucosal gland."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:5487122"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0046246) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046246" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19996346"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0046246) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpene anabolism" -- Class: [myoepithelial cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033003) +- [terpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0046246) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpene synthesis" -- [myoepithelial cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033003) EquivalentTo [myoepithelial cell](http://purl.obolibrary.org/obo/CL_0000185) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [bronchus submucosal gland](http://purl.obolibrary.org/obo/UBERON_8410043)) +- Class: [terpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0046246) -- [myoepithelial cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033003) SubClassOf [myoepithelial cell](http://purl.obolibrary.org/obo/CL_0000185) +- [terpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0046246) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [terpene](http://purl.obolibrary.org/obo/CHEBI_35186)) -- [myoepithelial cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033003) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [bronchus submucosal gland](http://purl.obolibrary.org/obo/UBERON_8410043) +- [terpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0046246) SubClassOf [hydrocarbon biosynthetic process](http://purl.obolibrary.org/obo/GO_0120251) -- [myoepithelial cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033003) SubClassOf [bronchial epithelial cell](http://purl.obolibrary.org/obo/CL_0002328) +- [terpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0046246) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) +- [terpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0046246) SubClassOf [terpene metabolic process](http://purl.obolibrary.org/obo/GO_0042214) -### naive T cell `http://purl.obolibrary.org/obo/CL_0000898` -#### Removed -- [naive T cell](http://purl.obolibrary.org/obo/CL_0000898) EquivalentTo [mature T cell](http://purl.obolibrary.org/obo/CL_0002419) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) +- [terpene biosynthetic process](http://purl.obolibrary.org/obo/GO_0046246) SubClassOf [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) -#### Added -- [naive T cell](http://purl.obolibrary.org/obo/CL_0000898) EquivalentTo [mature T cell](http://purl.obolibrary.org/obo/CL_0002419) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [C-C chemokine receptor type 7](http://purl.obolibrary.org/obo/PR_000001203)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-7 receptor subunit alpha](http://purl.obolibrary.org/obo/PR_000001869)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [L-selectin](http://purl.obolibrary.org/obo/PR_000001318)) and ([has low plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015016) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) -### negative regulation of melanin biosynthetic process `http://purl.obolibrary.org/obo/GO_0048022` +### terpene catabolic process `http://purl.obolibrary.org/obo/GO_0046247` #### Removed -- [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0048022" +- [terpene catabolic process](http://purl.obolibrary.org/obo/GO_0046247) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" -- [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of melanin biosynthetic process" +- [terpene catabolic process](http://purl.obolibrary.org/obo/GO_0046247) [label](http://www.w3.org/2000/01/rdf-schema#label) "terpene catabolic process" -- [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of melanin formation" +- [terpene catabolic process](http://purl.obolibrary.org/obo/GO_0046247) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046247" -- [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of melanin biosynthetic process" +- [terpene catabolic process](http://purl.obolibrary.org/obo/GO_0046247) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpene breakdown" -- [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of melanin biosynthetic process" +- [terpene catabolic process](http://purl.obolibrary.org/obo/GO_0046247) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpene catabolism" -- [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of melanin anabolism" +- [terpene catabolic process](http://purl.obolibrary.org/obo/GO_0046247) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpene degradation" -- [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of melanin biosynthesis" +- [terpene catabolic process](http://purl.obolibrary.org/obo/GO_0046247) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -- [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" +- Class: [terpene catabolic process](http://purl.obolibrary.org/obo/GO_0046247) -- [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of melanin biosynthetic process" +- [terpene catabolic process](http://purl.obolibrary.org/obo/GO_0046247) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [terpene](http://purl.obolibrary.org/obo/CHEBI_35186)) -- [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of melanin synthesis" +- [terpene catabolic process](http://purl.obolibrary.org/obo/GO_0046247) SubClassOf [hydrocarbon catabolic process](http://purl.obolibrary.org/obo/GO_0120253) -- [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jid" +- [terpene catabolic process](http://purl.obolibrary.org/obo/GO_0046247) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) + +- [terpene catabolic process](http://purl.obolibrary.org/obo/GO_0046247) SubClassOf [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) -- [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of melanin biosynthetic process" +- [terpene catabolic process](http://purl.obolibrary.org/obo/GO_0046247) SubClassOf [terpene metabolic process](http://purl.obolibrary.org/obo/GO_0042214) -- Class: [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) -- [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438)) -- [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) SubClassOf [regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048021) +### terpene metabolic process `http://purl.obolibrary.org/obo/GO_0042214` +#### Removed +- [terpene metabolic process](http://purl.obolibrary.org/obo/GO_0042214) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0042214" -- [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) SubClassOf [negative regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900377) +- [terpene metabolic process](http://purl.obolibrary.org/obo/GO_0042214) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:curators" -- [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) SubClassOf [negative regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031327) +- [terpene metabolic process](http://purl.obolibrary.org/obo/GO_0042214) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -- [negative regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048022) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) +- [terpene metabolic process](http://purl.obolibrary.org/obo/GO_0042214) [label](http://www.w3.org/2000/01/rdf-schema#label) "terpene metabolic process" +- [terpene metabolic process](http://purl.obolibrary.org/obo/GO_0042214) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpene metabolism" +- Class: [terpene metabolic process](http://purl.obolibrary.org/obo/GO_0042214) -### negative regulation of stomach neuroendocrine cell differentiation `http://purl.obolibrary.org/obo/GO_0061106` +- [terpene metabolic process](http://purl.obolibrary.org/obo/GO_0042214) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [terpene](http://purl.obolibrary.org/obo/CHEBI_35186)) -#### Added -- [negative regulation of stomach neuroendocrine cell differentiation](http://purl.obolibrary.org/obo/GO_0061106) SubClassOf [negative regulation of neuron differentiation](http://purl.obolibrary.org/obo/GO_0045665) +- [terpene metabolic process](http://purl.obolibrary.org/obo/GO_0042214) SubClassOf [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) +- [terpene metabolic process](http://purl.obolibrary.org/obo/GO_0042214) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) -### neuroendocrine cell `http://purl.obolibrary.org/obo/CL_0000165` -#### Removed -- [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "neurosecretory cell"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpene metabolic process](http://purl.obolibrary.org/obo/GO_0042214) SubClassOf [hydrocarbon metabolic process](http://purl.obolibrary.org/obo/GO_0120252) -- [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An endocrine cell that has the specialized function to produce and secrete hormones in response to neuronal signals."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D055099"^^[string](http://www.w3.org/2001/XMLSchema#string) -- [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) SubClassOf [electrically responsive cell](http://purl.obolibrary.org/obo/CL_0000393) -#### Added -- [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "The neurosecretory cell is neither an ordinary neuron nor an endocrine cell, but a combination of both. Its neuronal features resemble those of ordinary neurons concerning both structure and function. The production of a visible secretory material marks the neurosecretory neuron as a gland cell, and the fact that extractable cellular products act in the manner of hormones places it in the realm of endocrine elements. +### terpenoid `http://purl.obolibrary.org/obo/CHEBI_26873` +#### Removed +- [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Terpenoid" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -The modern definition of neurosecretion has evolved to include the release of any neuronal secretory product from a neuron." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:5342440"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "terpenoide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://www.clinicalkey.com/#!/content/book/3-s2.0-B9780323555968000073"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Terpenoid" -- [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A neuron that is capable of some hormone secretion in response to neuronal signals."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D055099"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any isoprenoid that is a natural product or related compound formally derived from isoprene units. Terpenoids may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the parent terpene. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group." -- [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "neurosecretory neuron"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpenoids" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005130"^^[string](http://www.w3.org/2001/XMLSchema#string) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "neurosecretory cell"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) [label](http://www.w3.org/2000/01/rdf-schema#label) "terpenoid" -- [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0000381" +- [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) EquivalentTo [neuron](http://purl.obolibrary.org/obo/CL_0000540) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [hormone secretion](http://purl.obolibrary.org/obo/GO_0046879)) +- [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) SubClassOf [efferent neuron](http://purl.obolibrary.org/obo/CL_0000527) +- [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26873" +- [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "terpenoides" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -### neuroendocrine cell differentiation `http://purl.obolibrary.org/obo/GO_0061101` +- Class: [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) -#### Added -- [neuroendocrine cell differentiation](http://purl.obolibrary.org/obo/GO_0061101) SubClassOf [neuron differentiation](http://purl.obolibrary.org/obo/GO_0030182) +- [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) SubClassOf [has_parent_hydride](http://purl.obolibrary.org/obo/chebi#has_parent_hydride) some [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) +- [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) SubClassOf [isoprenoid](http://purl.obolibrary.org/obo/CHEBI_24913) -### neuroendocrine cell of epithelium of crypt of Lieberkuhn `http://purl.obolibrary.org/obo/CL_4033002` -#### Added -- [neuroendocrine cell of epithelium of crypt of Lieberkuhn](http://purl.obolibrary.org/obo/CL_4033002) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A(n) neuroendocrine cell that is part of a(n) epithelium of crypt of Lieberkuhn."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:31390635"^^[string](http://www.w3.org/2001/XMLSchema#string) -- [neuroendocrine cell of epithelium of crypt of Lieberkuhn](http://purl.obolibrary.org/obo/CL_4033002) [label](http://www.w3.org/2000/01/rdf-schema#label) "neuroendocrine cell of epithelium of crypt of Lieberkuhn"^^[string](http://www.w3.org/2001/XMLSchema#string) +### terpenoid biosynthetic process `http://purl.obolibrary.org/obo/GO_0016114` +#### Removed +- [terpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016114) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpenoid synthesis" -- [neuroendocrine cell of epithelium of crypt of Lieberkuhn](http://purl.obolibrary.org/obo/CL_4033002) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) +- [terpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016114) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0016114" -- Class: [neuroendocrine cell of epithelium of crypt of Lieberkuhn](http://purl.obolibrary.org/obo/CL_4033002) +- [terpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016114) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -- [neuroendocrine cell of epithelium of crypt of Lieberkuhn](http://purl.obolibrary.org/obo/CL_4033002) EquivalentTo [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of crypt of Lieberkuhn](http://purl.obolibrary.org/obo/UBERON_0011184)) +- [terpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016114) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Terpenoid" -- [neuroendocrine cell of epithelium of crypt of Lieberkuhn](http://purl.obolibrary.org/obo/CL_4033002) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of crypt of Lieberkuhn](http://purl.obolibrary.org/obo/UBERON_0011184) +- [terpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016114) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" -- [neuroendocrine cell of epithelium of crypt of Lieberkuhn](http://purl.obolibrary.org/obo/CL_4033002) SubClassOf [intestinal epithelial cell](http://purl.obolibrary.org/obo/CL_0002563) +- [terpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016114) [label](http://www.w3.org/2000/01/rdf-schema#label) "terpenoid biosynthetic process" -- [neuroendocrine cell of epithelium of crypt of Lieberkuhn](http://purl.obolibrary.org/obo/CL_4033002) SubClassOf [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) +- [terpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016114) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpenoid formation" +- [terpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016114) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpenoid biosynthesis" -### neuroendocrine cell of epithelium of lobar bronchus `http://purl.obolibrary.org/obo/CL_4033010` +- [terpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016114) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpenoid anabolism" -#### Added -- [neuroendocrine cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033010) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A(n) neuroendocrine cell that is part of a(n) epithelium of lobar bronchus."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:26711336"^^[string](http://www.w3.org/2001/XMLSchema#string) +- Class: [terpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016114) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:33355253"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016114) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873)) -- [neuroendocrine cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033010) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) +- [terpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016114) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) -- [neuroendocrine cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033010) [label](http://www.w3.org/2000/01/rdf-schema#label) "neuroendocrine cell of epithelium of lobar bronchus"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016114) SubClassOf [terpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006721) -- Class: [neuroendocrine cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033010) +- [terpenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0016114) SubClassOf [isoprenoid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008299) -- [neuroendocrine cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033010) EquivalentTo [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of lobar bronchus](http://purl.obolibrary.org/obo/UBERON_0002339)) -- [neuroendocrine cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033010) SubClassOf [lung neuroendocrine cell](http://purl.obolibrary.org/obo/CL_1000223) -- [neuroendocrine cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033010) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of lobar bronchus](http://purl.obolibrary.org/obo/UBERON_0002339) +### terpenoid catabolic process `http://purl.obolibrary.org/obo/GO_0016115` +#### Removed +- [terpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016115) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpenoid degradation" -- [neuroendocrine cell of epithelium of lobar bronchus](http://purl.obolibrary.org/obo/CL_4033010) SubClassOf [bronchial epithelial cell](http://purl.obolibrary.org/obo/CL_0002328) +- [terpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016115) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0016115" +- [terpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016115) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpenoid breakdown" -### neurosecretory neuron `http://purl.obolibrary.org/obo/CL_0000381` -#### Removed -- [neurosecretory neuron](http://purl.obolibrary.org/obo/CL_0000381) [label](http://www.w3.org/2000/01/rdf-schema#label) "neurosecretory neuron"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016115) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" -- [neurosecretory neuron](http://purl.obolibrary.org/obo/CL_0000381) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005130"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016115) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -- [neurosecretory neuron](http://purl.obolibrary.org/obo/CL_0000381) EquivalentTo [neuron](http://purl.obolibrary.org/obo/CL_0000540) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [hormone secretion](http://purl.obolibrary.org/obo/GO_0046879)) +- [terpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016115) [label](http://www.w3.org/2000/01/rdf-schema#label) "terpenoid catabolic process" -- [neurosecretory neuron](http://purl.obolibrary.org/obo/CL_0000381) SubClassOf [secretory cell](http://purl.obolibrary.org/obo/CL_0000151) +- [terpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016115) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpenoid catabolism" -- [neurosecretory neuron](http://purl.obolibrary.org/obo/CL_0000381) SubClassOf [capable of](http://purl.obolibrary.org/obo/RO_0002215) some [hormone secretion](http://purl.obolibrary.org/obo/GO_0046879) +- Class: [terpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016115) -- [neurosecretory neuron](http://purl.obolibrary.org/obo/CL_0000381) SubClassOf [efferent neuron](http://purl.obolibrary.org/obo/CL_0000527) +- [terpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016115) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873)) -#### Added -- [neurosecretory neuron](http://purl.obolibrary.org/obo/CL_0000381) [deprecated](http://www.w3.org/2002/07/owl#deprecated) true +- [terpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016115) SubClassOf [isoprenoid catabolic process](http://purl.obolibrary.org/obo/GO_0008300) -- [neurosecretory neuron](http://purl.obolibrary.org/obo/CL_0000381) [label](http://www.w3.org/2000/01/rdf-schema#label) "obsolete neurosecretory neuron"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016115) SubClassOf [terpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006721) -- [neurosecretory neuron](http://purl.obolibrary.org/obo/CL_0000381) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "https://github.com/obophenotype/cell-ontology/issues/1784 -'neuroendocrine cell' (which has exact synonym "neurosecretory cell") and 'neurosecretory neuron' may all refer to the same cell type."^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpenoid catabolic process](http://purl.obolibrary.org/obo/GO_0016115) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) -- [neurosecretory neuron](http://purl.obolibrary.org/obo/CL_0000381) [term replaced by](http://purl.obolibrary.org/obo/IAO_0100001) [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) -### non-classical monocyte `http://purl.obolibrary.org/obo/CL_0000875` +### terpenoid metabolic process `http://purl.obolibrary.org/obo/GO_0006721` #### Removed -- [non-classical monocyte](http://purl.obolibrary.org/obo/CL_0000875) EquivalentTo [monocyte](http://purl.obolibrary.org/obo/CL_0000576) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [decreased size](http://purl.obolibrary.org/obo/PATO_0000587)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [lymphocyte costimulation](http://purl.obolibrary.org/obo/GO_0031294)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206)) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [monocyte differentiation](http://purl.obolibrary.org/obo/GO_0030224)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) +- [terpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006721) [label](http://www.w3.org/2000/01/rdf-schema#label) "terpenoid metabolic process" -- [non-classical monocyte](http://purl.obolibrary.org/obo/CL_0000875) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [monocyte differentiation](http://purl.obolibrary.org/obo/GO_0030224) +- [terpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006721) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "terpenoid metabolism" -#### Added -- [non-classical monocyte](http://purl.obolibrary.org/obo/CL_0000875) EquivalentTo [monocyte](http://purl.obolibrary.org/obo/CL_0000576) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [decreased size](http://purl.obolibrary.org/obo/PATO_0000587)) and ([capable of](http://purl.obolibrary.org/obo/RO_0002215) some [lymphocyte costimulation](http://purl.obolibrary.org/obo/GO_0031294)) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [monocyte differentiation](http://purl.obolibrary.org/obo/GO_0030224)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [CX3C chemokine receptor 1](http://purl.obolibrary.org/obo/PR_000001206)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) +- [terpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006721) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" -- [non-classical monocyte](http://purl.obolibrary.org/obo/CL_0000875) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [monocyte differentiation](http://purl.obolibrary.org/obo/GO_0030224) +- [terpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006721) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006721" +- [terpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006721) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -### non-material anatomical boundary `http://purl.obolibrary.org/obo/UBERON_0000015` +- Class: [terpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006721) -#### Added -- [non-material anatomical boundary](http://purl.obolibrary.org/obo/UBERON_0000015) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [terpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006721) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873)) -- [non-material anatomical boundary](http://purl.obolibrary.org/obo/UBERON_0000015) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [terpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006721) SubClassOf [isoprenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006720) -- [non-material anatomical boundary](http://purl.obolibrary.org/obo/UBERON_0000015) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [terpenoid metabolic process](http://purl.obolibrary.org/obo/GO_0006721) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) -- [non-material anatomical boundary](http://purl.obolibrary.org/obo/UBERON_0000015) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) -### non-pigmented ciliary epithelial cell `http://purl.obolibrary.org/obo/CL_0002304` +### terpenoid transport `http://purl.obolibrary.org/obo/GO_0046865` #### Removed -- [non-pigmented ciliary epithelial cell](http://purl.obolibrary.org/obo/CL_0002304) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "NPE"^^[string](http://www.w3.org/2001/XMLSchema#string) - -- [non-pigmented ciliary epithelial cell](http://purl.obolibrary.org/obo/CL_0002304) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A multi-ciliated cell of the retina that lacks visual pigment and contributes to aqueous humor by secreting chloride ions. This cell type maintains gap junctions with pigmented epithelial cells."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tfm" +- [terpenoid transport](http://purl.obolibrary.org/obo/GO_0046865) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046865" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15106942"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpenoid transport](http://purl.obolibrary.org/obo/GO_0046865) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -- [non-pigmented ciliary epithelial cell](http://purl.obolibrary.org/obo/CL_0002304) SubClassOf [multi-ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_0005012) +- [terpenoid transport](http://purl.obolibrary.org/obo/GO_0046865) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of terpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Terpenoids are a class of compounds characterized by an isoprenoid chemical structure and include derivatives with various functional groups." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" -#### Added -- [non-pigmented ciliary epithelial cell](http://purl.obolibrary.org/obo/CL_0002304) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "NPE cell"^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://doi.org/10.1016/j.exer.2003.09.021"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpenoid transport](http://purl.obolibrary.org/obo/GO_0046865) [label](http://www.w3.org/2000/01/rdf-schema#label) "terpenoid transport" -- [non-pigmented ciliary epithelial cell](http://purl.obolibrary.org/obo/CL_0002304) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "In a consensus model of unidirectional secretion, aqueous humour is formed by transferring solute, principally NaCl, from stroma to posterior chamber, with water passively following the osmotic gradient. Unidirectional secretion comprises three sequential steps. First, NaCl is transferred from the stromal interstitium into the pigmented ciliary epithelial (PE) cells. Second, solute passes from the PE into the non-pigmented ciliary epithelial (NPE) cells through gap junctions. Finally, NPE cells release Na+ and Cl− into the aqueous humour."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://doi.org/10.1016/j.exer.2003.09.021"^^[string](http://www.w3.org/2001/XMLSchema#string) +- Class: [terpenoid transport](http://purl.obolibrary.org/obo/GO_0046865) -- [non-pigmented ciliary epithelial cell](http://purl.obolibrary.org/obo/CL_0002304) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A cell that is part of non-pigmented ciliary epithelium. This cell type participates in aqueous humor formation by releasing solute, principally sodium and chloride ions received from pigmented epithelial cells via gap junctions, into the aqueous humor of the eye."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tfm" +- [terpenoid transport](http://purl.obolibrary.org/obo/GO_0046865) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873)) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15106942"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpenoid transport](http://purl.obolibrary.org/obo/GO_0046865) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [terpenoid](http://purl.obolibrary.org/obo/CHEBI_26873) -- [non-pigmented ciliary epithelial cell](http://purl.obolibrary.org/obo/CL_0002304) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nonpigmented ciliary epithelial cell"^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10913011"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [terpenoid transport](http://purl.obolibrary.org/obo/GO_0046865) SubClassOf [isoprenoid transport](http://purl.obolibrary.org/obo/GO_0046864) -- [non-pigmented ciliary epithelial cell](http://purl.obolibrary.org/obo/CL_0002304) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [ciliary epithelium](http://purl.obolibrary.org/obo/UBERON_0001778) -### odontoblast `http://purl.obolibrary.org/obo/CL_0000060` +### testosterone `http://purl.obolibrary.org/obo/CHEBI_17347` #### Removed -- [odontoblast](http://purl.obolibrary.org/obo/CL_0000060) SubClassOf [general ecto-epithelial cell](http://purl.obolibrary.org/obo/CL_0002159) - -#### Added -- [odontoblast](http://purl.obolibrary.org/obo/CL_0000060) SubClassOf [dental pulp cell](http://purl.obolibrary.org/obo/CL_0002148) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "testosterona" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) -### organ `http://purl.obolibrary.org/obo/UBERON_0000062` +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11786693" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -#### Added -- [organ](http://purl.obolibrary.org/obo/UBERON_0000062) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00535" -- [organ](http://purl.obolibrary.org/obo/UBERON_0000062) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" -- [organ](http://purl.obolibrary.org/obo/UBERON_0000062) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:26883" -- [organ](http://purl.obolibrary.org/obo/UBERON_0000062) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:58-22-0" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:1915399" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" -### organ part `http://purl.obolibrary.org/obo/UBERON_0000064` +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5.." -#### Added -- [organ part](http://purl.obolibrary.org/obo/UBERON_0000064) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [mass](http://purl.obolibrary.org/obo/chebi/mass) "288.42440" -- [organ part](http://purl.obolibrary.org/obo/UBERON_0000064) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB00624" -- [organ part](http://purl.obolibrary.org/obo/UBERON_0000064) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10438974" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [organ part](http://purl.obolibrary.org/obo/UBERON_0000064) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [label](http://www.w3.org/2000/01/rdf-schema#label) "testosterone" +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000234" -### organ system subdivision `http://purl.obolibrary.org/obo/UBERON_0011216` +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Drug_Central:2607" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "DrugCentral" -#### Added -- [organ system subdivision](http://purl.obolibrary.org/obo/UBERON_0011216) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:58-22-0" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" -- [organ system subdivision](http://purl.obolibrary.org/obo/UBERON_0011216) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "4-androsten-17beta-ol-3-one" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" -- [organ system subdivision](http://purl.obolibrary.org/obo/UBERON_0011216) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "17beta-Hydroxy-4-androsten-3-one" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" -- [organ system subdivision](http://purl.obolibrary.org/obo/UBERON_0011216) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:17347" +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:3653705" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" -### organism subdivision `http://purl.obolibrary.org/obo/UBERON_0000475` +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Testosterone" -#### Added -- [organism subdivision](http://purl.obolibrary.org/obo/UBERON_0000475) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24498482" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [organism subdivision](http://purl.obolibrary.org/obo/UBERON_0000475) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Testosterone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" -- [organism subdivision](http://purl.obolibrary.org/obo/UBERON_0000475) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "testosterone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" -- [organism subdivision](http://purl.obolibrary.org/obo/UBERON_0000475) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@@H](O)CC[C@@]21[H]" -### organism substance `http://purl.obolibrary.org/obo/UBERON_0000463` +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:538843" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" -#### Added -- [organism substance](http://purl.obolibrary.org/obo/UBERON_0000463) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "TESTOSTERONE" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" -- [organism substance](http://purl.obolibrary.org/obo/UBERON_0000463) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1" -- [organism substance](http://purl.obolibrary.org/obo/UBERON_0000463) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D00075" -- [organism substance](http://purl.obolibrary.org/obo/UBERON_0000463) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:15214" +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "LIPID_MAPS_instance:LMST02020002" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "LIPID MAPS" -### palatoquadrate arch `http://purl.obolibrary.org/obo/UBERON_0011085` -#### Removed -- [palatoquadrate arch](http://purl.obolibrary.org/obo/UBERON_0011085) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00003675" -#### Added -- [palatoquadrate arch](http://purl.obolibrary.org/obo/UBERON_0011085) SubClassOf [anatomical entity](http://purl.obolibrary.org/obo/CARO_0000000) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "288.20893" +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "testosteronum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" -### papillary tips cell `http://purl.obolibrary.org/obo/CL_1000597` + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) -#### Added -- [papillary tips cell](http://purl.obolibrary.org/obo/CL_1000597) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A cell that is part of a tip of a renal papilla." +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C19H28O2" +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "testosterone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" -### parvocellular neurosecretory cell `http://purl.obolibrary.org/obo/CL_1001505` -#### Removed -- [parvocellular neurosecretory cell](http://purl.obolibrary.org/obo/CL_1001505) SubClassOf [neurosecretory neuron](http://purl.obolibrary.org/obo/CL_0000381) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "17beta-hydroxyandrost-4-en-3-one" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [parvocellular neurosecretory cell](http://purl.obolibrary.org/obo/CL_1001505) SubClassOf [anatomical entity](http://purl.obolibrary.org/obo/CARO_0000000) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -#### Added -- [parvocellular neurosecretory cell](http://purl.obolibrary.org/obo/CL_1001505) SubClassOf [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18900503" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:1915399" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" -### peg cell `http://purl.obolibrary.org/obo/CL_4033014` +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "MUMGGOZAMZWBJJ-DYKIIFRCSA-N" -#### Added -- [peg cell](http://purl.obolibrary.org/obo/CL_4033014) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "In vitro evidence supports a stem-cell/regenerative function for these cells"^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22911892"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [peg cell](http://purl.obolibrary.org/obo/CL_4033014) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fallopian tube epithelial stem-like cell" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22911892"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:58-22-0" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" -- [peg cell](http://purl.obolibrary.org/obo/CL_4033014) [date](http://purl.org/dc/terms/date) "2023-02-02T15:07:12Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [peg cell](http://purl.obolibrary.org/obo/CL_4033014) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "intercalary cell" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22911892"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "17beta-hydroxy-4-androsten-3-one" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [peg cell](http://purl.obolibrary.org/obo/CL_4033014) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A small, narrow, peg-shaped epithelial cell with little cytoplasm that is part of oviduct epithelium. This cell is rarer than the ciliated and secretory epithelial cells of the fallopian tube epithelium and is often found intercalated between them. Peg cells are generally distributed basally along the epithelium and have been found in high concentrations at the fimbriated, distal end of the fallopian tube in humans. It may have a regenerative/stem-cell function. In humans, markers include EPCAM, CD44, and ITGA6."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22911892"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Testosteron" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:2210508"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Androderm" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30023181"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:TES" -- [peg cell](http://purl.obolibrary.org/obo/CL_4033014) [label](http://www.w3.org/2000/01/rdf-schema#label) "peg cell"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:9461" -- [peg cell](http://purl.obolibrary.org/obo/CL_4033014) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "FTE stem-like cell" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22911892"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:45798" -- [peg cell](http://purl.obolibrary.org/obo/CL_4033014) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "FTESC" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22911892"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) SubClassOf [C19-steroid](http://purl.obolibrary.org/obo/CHEBI_131621) - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [abbreviation](http://purl.obolibrary.org/obo/cl#abbreviation) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) -- [peg cell](http://purl.obolibrary.org/obo/CL_4033014) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) SubClassOf [17beta-hydroxy steroid](http://purl.obolibrary.org/obo/CHEBI_35343) -- Class: [peg cell](http://purl.obolibrary.org/obo/CL_4033014) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) -- [peg cell](http://purl.obolibrary.org/obo/CL_4033014) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [oviduct epithelium](http://purl.obolibrary.org/obo/UBERON_0004804) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Daphnia magna metabolite](http://purl.obolibrary.org/obo/CHEBI_83056) -- [peg cell](http://purl.obolibrary.org/obo/CL_4033014) SubClassOf [epithelial cell](http://purl.obolibrary.org/obo/CL_0000066) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) SubClassOf [androstanoid](http://purl.obolibrary.org/obo/CHEBI_50402) +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [androgen](http://purl.obolibrary.org/obo/CHEBI_50113) -### peptidergic neuron `http://purl.obolibrary.org/obo/CL_0000110` +- [testosterone](http://purl.obolibrary.org/obo/CHEBI_17347) SubClassOf [3-oxo-Delta(4) steroid](http://purl.obolibrary.org/obo/CHEBI_47909) -#### Added -- [peptidergic neuron](http://purl.obolibrary.org/obo/CL_0000110) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004101"^^[string](http://www.w3.org/2001/XMLSchema#string) -### perineural cell `http://purl.obolibrary.org/obo/CL_0002576` +### testosterone biosynthetic process `http://purl.obolibrary.org/obo/GO_0061370` #### Removed -- [perineural cell](http://purl.obolibrary.org/obo/CL_0002576) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A myofibroblast that lies in the connective tissue of the spinal cord that has a distinctly lamellar arrangement."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO:tfm"^^[string](http://www.w3.org/2001/XMLSchema#string) - - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://en.wikipedia.org/wiki/Perineurium"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [testosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_0061370) SubClassOf [olefinic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0120255) -- [perineural cell](http://purl.obolibrary.org/obo/CL_0002576) [label](http://www.w3.org/2000/01/rdf-schema#label) "perineural cell"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [testosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_0061370) SubClassOf [steroid biosynthetic process](http://purl.obolibrary.org/obo/GO_0006694) -- [perineural cell](http://purl.obolibrary.org/obo/CL_0002576) EquivalentTo [myofibroblast cell](http://purl.obolibrary.org/obo/CL_0000186) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [perineurium](http://purl.obolibrary.org/obo/UBERON_0000121)) +- [testosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_0061370) SubClassOf [ketone biosynthetic process](http://purl.obolibrary.org/obo/GO_0042181) -- [perineural cell](http://purl.obolibrary.org/obo/CL_0002576) SubClassOf [myofibroblast cell](http://purl.obolibrary.org/obo/CL_0000186) - - [is_inferred](http://www.geneontology.org/formats/oboInOwl#is_inferred) "true" - -- [perineural cell](http://purl.obolibrary.org/obo/CL_0002576) SubClassOf [neural cell](http://purl.obolibrary.org/obo/CL_0002319) +- [testosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_0061370) SubClassOf [organic hydroxy compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901617) #### Added -- [perineural cell](http://purl.obolibrary.org/obo/CL_0002576) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "There are studies that largely accept the idea that the perineurial cell is a modified fibroblast with myofibroblastic features."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:36244793"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [testosterone biosynthetic process](http://purl.obolibrary.org/obo/GO_0061370) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) -- [perineural cell](http://purl.obolibrary.org/obo/CL_0002576) [label](http://www.w3.org/2000/01/rdf-schema#label) "perineurial cell"^^[string](http://www.w3.org/2001/XMLSchema#string) -- [perineural cell](http://purl.obolibrary.org/obo/CL_0002576) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A glial cell that is part of the perineurium. This cell type has thin long bipolar cytoplasmic processes, pinocytotic vesicles, fragments of external lamina and/or external lamina-like material, attachment plaques, and desmosome-like junctions. Perineurial cells historically have been referred to as fibroblasts because of shape; however, unlike fibroblasts, a perineurial cell: does not have a compact nucleus and large endoplasmic reticulum; does have a double basement membrane opposed to a single basal lamina; is carefully joined to other perineurial cells by tight junctions into a single sheet as opposed to arranged in a large mass; and finally, can surround a small axon bundle at a nerve terminal whereas a fibroblast cannot."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25818566"^^[string](http://www.w3.org/2001/XMLSchema#string) +### testosterone secretion `http://purl.obolibrary.org/obo/GO_0035936` +#### Removed +- [testosterone secretion](http://purl.obolibrary.org/obo/GO_0035936) SubClassOf [organic hydroxy compound transport](http://purl.obolibrary.org/obo/GO_0015850) + +- [testosterone secretion](http://purl.obolibrary.org/obo/GO_0035936) SubClassOf [lipid export from cell](http://purl.obolibrary.org/obo/GO_0140353) - - [comment](http://www.w3.org/2000/01/rdf-schema#comment) [0000-0001-7655-4833](https://orcid.org/0000-0001-7655-4833) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO:tfm"^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NCIT:C41442"^^[string](http://www.w3.org/2001/XMLSchema#string) +### tetrapyrrole `http://purl.obolibrary.org/obo/CHEBI_26932` +#### Removed +- [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetrapyrrole" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://en.wikipedia.org/wiki/Perineurium"^^[string](http://www.w3.org/2001/XMLSchema#string) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [perineural cell](http://purl.obolibrary.org/obo/CL_0002576) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "perineurial glial cell"^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25818566"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26932" -- [perineural cell](http://purl.obolibrary.org/obo/CL_0002576) SubClassOf [glial cell](http://purl.obolibrary.org/obo/CL_0000125) +- [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) +- [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932) [label](http://www.w3.org/2000/01/rdf-schema#label) "tetrapyrrole" -### perineurium `http://purl.obolibrary.org/obo/UBERON_0000121` -#### Removed -- [perineurium](http://purl.obolibrary.org/obo/UBERON_0000121) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A layer of thin, concentrically arranged cells with interspersed collagen that lies within the epineurium. (Nolte, J., The Human Brain 3rd edition)." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NLXANAT:090205" +- [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [perineurium](http://purl.obolibrary.org/obo/UBERON_0000121) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [nervous system](http://purl.obolibrary.org/obo/UBERON_0001016) +- [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." -#### Added -- [perineurium](http://purl.obolibrary.org/obo/UBERON_0000121) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A layer of thin, concentrically arranged cells with interspersed collagen that lies within the epineurium. The perineurium is a component of the blood–nerve barrier and is essential for protecting axons and their associated Schwann cells from ionic flux, toxins and infection." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25818566"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a tetrapyrrole" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18434767" +- [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetrapyrroles" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NLXANAT:090205" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [perineurium](http://purl.obolibrary.org/obo/UBERON_0000121) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [blood nerve barrier](http://purl.obolibrary.org/obo/UBERON_0003209) +- Class: [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932) +- [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932) SubClassOf [polypyrrole](http://purl.obolibrary.org/obo/CHEBI_38077) -### peritubular capillary endothelial cell `http://purl.obolibrary.org/obo/CL_1001033` +- [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932) SubClassOf [heteroarene](http://purl.obolibrary.org/obo/CHEBI_33833) -#### Added -- [peritubular capillary endothelial cell](http://purl.obolibrary.org/obo/CL_1001033) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An endothelial cell that is part of some peritubular capillary." -### pharyngeal arch cartilage `http://purl.obolibrary.org/obo/UBERON_0011004` +### tetrapyrrole binding `http://purl.obolibrary.org/obo/GO_0046906` #### Removed -- [pharyngeal arch cartilage](http://purl.obolibrary.org/obo/UBERON_0011004) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [tetrapyrrole binding](http://purl.obolibrary.org/obo/GO_0046906) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "porphyrin binding" +- [tetrapyrrole binding](http://purl.obolibrary.org/obo/GO_0046906) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046906" +- [tetrapyrrole binding](http://purl.obolibrary.org/obo/GO_0046906) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_pir](http://purl.obolibrary.org/obo/go#goslim_pir) -### phrenic nerve `http://purl.obolibrary.org/obo/UBERON_0001884` -#### Removed -- [phrenic nerve](http://purl.obolibrary.org/obo/UBERON_0001884) EquivalentTo [nerve](http://purl.obolibrary.org/obo/UBERON_0001021) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [diaphragm](http://purl.obolibrary.org/obo/UBERON_0001103)) - -- [phrenic nerve](http://purl.obolibrary.org/obo/UBERON_0001884) SubClassOf [thoracic cavity artery](http://purl.obolibrary.org/obo/UBERON_0003473) +- [tetrapyrrole binding](http://purl.obolibrary.org/obo/GO_0046906) [label](http://www.w3.org/2000/01/rdf-schema#label) "tetrapyrrole binding" -- [phrenic nerve](http://purl.obolibrary.org/obo/UBERON_0001884) SubClassOf [supplies](http://purl.obolibrary.org/obo/RO_0002178) some [diaphragm](http://purl.obolibrary.org/obo/UBERON_0001103) +- [tetrapyrrole binding](http://purl.obolibrary.org/obo/GO_0046906) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:curators" -#### Added -- [phrenic nerve](http://purl.obolibrary.org/obo/UBERON_0001884) EquivalentTo [nerve](http://purl.obolibrary.org/obo/UBERON_0001021) and ([innervates](http://purl.obolibrary.org/obo/RO_0002134) some [diaphragm](http://purl.obolibrary.org/obo/UBERON_0001103)) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" -- [phrenic nerve](http://purl.obolibrary.org/obo/UBERON_0001884) SubClassOf [neuron projection bundle](http://purl.obolibrary.org/obo/CARO_0001001) +- [tetrapyrrole binding](http://purl.obolibrary.org/obo/GO_0046906) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" -- [phrenic nerve](http://purl.obolibrary.org/obo/UBERON_0001884) SubClassOf [innervates](http://purl.obolibrary.org/obo/RO_0002134) some [diaphragm](http://purl.obolibrary.org/obo/UBERON_0001103) +- [tetrapyrrole binding](http://purl.obolibrary.org/obo/GO_0046906) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_metagenomics](http://purl.obolibrary.org/obo/go#goslim_metagenomics) +- Class: [tetrapyrrole binding](http://purl.obolibrary.org/obo/GO_0046906) -### pigment biosynthetic process `http://purl.obolibrary.org/obo/GO_0046148` -#### Removed -- [pigment biosynthetic process](http://purl.obolibrary.org/obo/GO_0046148) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pigment synthesis" +- [tetrapyrrole binding](http://purl.obolibrary.org/obo/GO_0046906) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932)) -- [pigment biosynthetic process](http://purl.obolibrary.org/obo/GO_0046148) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" +- [tetrapyrrole binding](http://purl.obolibrary.org/obo/GO_0046906) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932) -- [pigment biosynthetic process](http://purl.obolibrary.org/obo/GO_0046148) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" +- [tetrapyrrole binding](http://purl.obolibrary.org/obo/GO_0046906) SubClassOf [organic cyclic compound binding](http://purl.obolibrary.org/obo/GO_0097159) -- [pigment biosynthetic process](http://purl.obolibrary.org/obo/GO_0046148) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pigment formation" +- [tetrapyrrole binding](http://purl.obolibrary.org/obo/GO_0046906) SubClassOf [heterocyclic compound binding](http://purl.obolibrary.org/obo/GO_1901363) -- [pigment biosynthetic process](http://purl.obolibrary.org/obo/GO_0046148) [label](http://www.w3.org/2000/01/rdf-schema#label) "pigment biosynthetic process" -- [pigment biosynthetic process](http://purl.obolibrary.org/obo/GO_0046148) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pigment biosynthesis" -- [pigment biosynthetic process](http://purl.obolibrary.org/obo/GO_0046148) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pigment anabolism" +### tetrapyrrole biosynthetic process `http://purl.obolibrary.org/obo/GO_0033014` +#### Removed +- [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0033014" -- [pigment biosynthetic process](http://purl.obolibrary.org/obo/GO_0046148) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046148" +- [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -- Class: [pigment biosynthetic process](http://purl.obolibrary.org/obo/GO_0046148) +- [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetrapyrrole formation" -- [pigment biosynthetic process](http://purl.obolibrary.org/obo/GO_0046148) SubClassOf [pigment metabolic process](http://purl.obolibrary.org/obo/GO_0042440) +- [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) [label](http://www.w3.org/2000/01/rdf-schema#label) "tetrapyrrole biosynthetic process" +- [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetrapyrrole synthesis" +- [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetrapyrrole anabolism" -### pigment catabolic process `http://purl.obolibrary.org/obo/GO_0046149` -#### Removed -- [pigment catabolic process](http://purl.obolibrary.org/obo/GO_0046149) [label](http://www.w3.org/2000/01/rdf-schema#label) "pigment catabolic process" +- [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" -- [pigment catabolic process](http://purl.obolibrary.org/obo/GO_0046149) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pigment catabolism" +- [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetrapyrrole biosynthesis" -- [pigment catabolic process](http://purl.obolibrary.org/obo/GO_0046149) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of a pigment, any general or particular coloring matter in living organisms, e.g. melanin." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" +- Class: [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) -- [pigment catabolic process](http://purl.obolibrary.org/obo/GO_0046149) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pigment degradation" +- [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932)) -- [pigment catabolic process](http://purl.obolibrary.org/obo/GO_0046149) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pigment breakdown" +- [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) SubClassOf [organic cyclic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901362) -- [pigment catabolic process](http://purl.obolibrary.org/obo/GO_0046149) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" +- [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932) -- [pigment catabolic process](http://purl.obolibrary.org/obo/GO_0046149) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046149" +- [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) SubClassOf [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) -- Class: [pigment catabolic process](http://purl.obolibrary.org/obo/GO_0046149) +- [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) SubClassOf [cellular nitrogen compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044271) -- [pigment catabolic process](http://purl.obolibrary.org/obo/GO_0046149) SubClassOf [pigment metabolic process](http://purl.obolibrary.org/obo/GO_0042440) +- [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) SubClassOf [aromatic compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0019438) +- [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) SubClassOf [organonitrogen compound biosynthetic process](http://purl.obolibrary.org/obo/GO_1901566) +- [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) SubClassOf [heterocycle biosynthetic process](http://purl.obolibrary.org/obo/GO_0018130) -### pigment metabolic process `http://purl.obolibrary.org/obo/GO_0042440` -#### Removed -- [pigment metabolic process](http://purl.obolibrary.org/obo/GO_0042440) [label](http://www.w3.org/2000/01/rdf-schema#label) "pigment metabolic process" -- [pigment metabolic process](http://purl.obolibrary.org/obo/GO_0042440) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -- [pigment metabolic process](http://purl.obolibrary.org/obo/GO_0042440) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_drosophila](http://purl.obolibrary.org/obo/go#goslim_drosophila) +### tetrapyrrole biosynthetic process from glutamate `http://purl.obolibrary.org/obo/GO_0033526` +#### Removed +- [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetrapyrrole biosynthesis from glutamate" -- [pigment metabolic process](http://purl.obolibrary.org/obo/GO_0042440) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" +- [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526) [label](http://www.w3.org/2000/01/rdf-schema#label) "tetrapyrrole biosynthetic process from glutamate" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" +- [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetrapyrrole formation from glutamate" -- [pigment metabolic process](http://purl.obolibrary.org/obo/GO_0042440) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0042440" +- [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" -- [pigment metabolic process](http://purl.obolibrary.org/obo/GO_0042440) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pigment metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:PWY-5188" -- [pigment metabolic process](http://purl.obolibrary.org/obo/GO_0042440) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_pir](http://purl.obolibrary.org/obo/go#goslim_pir) +- [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -- Class: [pigment metabolic process](http://purl.obolibrary.org/obo/GO_0042440) +- [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:PWY-5188" -- [pigment metabolic process](http://purl.obolibrary.org/obo/GO_0042440) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) +- [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0033526" +- [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetrapyrrole synthesis from glutamate" +- [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetrapyrrole anabolism from glutamate" -### pigment metabolic process involved in developmental pigmentation `http://purl.obolibrary.org/obo/GO_0043324` -#### Removed -- [pigment metabolic process involved in developmental pigmentation](http://purl.obolibrary.org/obo/GO_0043324) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" +- Class: [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526) -- [pigment metabolic process involved in developmental pigmentation](http://purl.obolibrary.org/obo/GO_0043324) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pigment metabolism during developmental pigmentation" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" +- [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932)) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321)) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" +- [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [glutamate(1-)](http://purl.obolibrary.org/obo/CHEBI_14321) -- [pigment metabolic process involved in developmental pigmentation](http://purl.obolibrary.org/obo/GO_0043324) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pigment metabolic process during developmental pigmentation" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" +- [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526) SubClassOf [glutamate metabolic process](http://purl.obolibrary.org/obo/GO_0006536) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" +- [tetrapyrrole biosynthetic process from glutamate](http://purl.obolibrary.org/obo/GO_0033526) SubClassOf [tetrapyrrole biosynthetic process](http://purl.obolibrary.org/obo/GO_0033014) -- [pigment metabolic process involved in developmental pigmentation](http://purl.obolibrary.org/obo/GO_0043324) [label](http://www.w3.org/2000/01/rdf-schema#label) "pigment metabolic process involved in developmental pigmentation" -- [pigment metabolic process involved in developmental pigmentation](http://purl.obolibrary.org/obo/GO_0043324) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving biological pigments e.g. melanin, occurring as part of the development of an organ or organism." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" +### tetrapyrrole catabolic process `http://purl.obolibrary.org/obo/GO_0033015` +#### Removed +- [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetrapyrrole degradation" -- [pigment metabolic process involved in developmental pigmentation](http://purl.obolibrary.org/obo/GO_0043324) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0043324" +- [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetrapyrrole breakdown" -- Class: [pigment metabolic process involved in developmental pigmentation](http://purl.obolibrary.org/obo/GO_0043324) +- [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" -- [pigment metabolic process involved in developmental pigmentation](http://purl.obolibrary.org/obo/GO_0043324) EquivalentTo [pigment metabolic process](http://purl.obolibrary.org/obo/GO_0042440) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [developmental pigmentation](http://purl.obolibrary.org/obo/GO_0048066)) +- [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) [label](http://www.w3.org/2000/01/rdf-schema#label) "tetrapyrrole catabolic process" -- [pigment metabolic process involved in developmental pigmentation](http://purl.obolibrary.org/obo/GO_0043324) SubClassOf [pigment metabolic process involved in pigmentation](http://purl.obolibrary.org/obo/GO_0043474) +- [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -- [pigment metabolic process involved in developmental pigmentation](http://purl.obolibrary.org/obo/GO_0043324) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [developmental pigmentation](http://purl.obolibrary.org/obo/GO_0048066) +- [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0033015" +- [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetrapyrrole catabolism" +- Class: [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) -### pigment metabolic process involved in pigmentation `http://purl.obolibrary.org/obo/GO_0043474` -#### Removed -- [pigment metabolic process involved in pigmentation](http://purl.obolibrary.org/obo/GO_0043474) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pigment metabolic process during pigmentation" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" +- [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932)) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" +- [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) SubClassOf [cellular nitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_0044270) -- [pigment metabolic process involved in pigmentation](http://purl.obolibrary.org/obo/GO_0043474) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" +- [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) SubClassOf [heterocycle catabolic process](http://purl.obolibrary.org/obo/GO_0046700) -- [pigment metabolic process involved in pigmentation](http://purl.obolibrary.org/obo/GO_0043474) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0043474" +- [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) SubClassOf [organonitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_1901565) -- [pigment metabolic process involved in pigmentation](http://purl.obolibrary.org/obo/GO_0043474) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pigment metabolism during pigmentation" +- [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) SubClassOf [aromatic compound catabolic process](http://purl.obolibrary.org/obo/GO_0019439) -- [pigment metabolic process involved in pigmentation](http://purl.obolibrary.org/obo/GO_0043474) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" +- [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) SubClassOf [organic cyclic compound catabolic process](http://purl.obolibrary.org/obo/GO_1901361) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jl" +- [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) SubClassOf [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" +- [tetrapyrrole catabolic process](http://purl.obolibrary.org/obo/GO_0033015) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932) -- [pigment metabolic process involved in pigmentation](http://purl.obolibrary.org/obo/GO_0043474) [label](http://www.w3.org/2000/01/rdf-schema#label) "pigment metabolic process involved in pigmentation" -- Class: [pigment metabolic process involved in pigmentation](http://purl.obolibrary.org/obo/GO_0043474) -- [pigment metabolic process involved in pigmentation](http://purl.obolibrary.org/obo/GO_0043474) EquivalentTo [pigment metabolic process](http://purl.obolibrary.org/obo/GO_0042440) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [pigmentation](http://purl.obolibrary.org/obo/GO_0043473)) +### tetrapyrrole metabolic process `http://purl.obolibrary.org/obo/GO_0033013` +#### Removed +- [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) [label](http://www.w3.org/2000/01/rdf-schema#label) "tetrapyrrole metabolic process" -- [pigment metabolic process involved in pigmentation](http://purl.obolibrary.org/obo/GO_0043474) SubClassOf [pigment metabolic process](http://purl.obolibrary.org/obo/GO_0042440) +- [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_pombe](http://purl.obolibrary.org/obo/go#goslim_pombe) -- [pigment metabolic process involved in pigmentation](http://purl.obolibrary.org/obo/GO_0043474) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [pigmentation](http://purl.obolibrary.org/obo/GO_0043473) +- [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" +- [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) +- [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0033013" -### pigmented ciliary epithelial cell `http://purl.obolibrary.org/obo/CL_0002303` -#### Removed -- [pigmented ciliary epithelial cell](http://purl.obolibrary.org/obo/CL_0002303) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A ciliated epithelial cell of the retina, this cell type uptakes sodium chloride and passes it to non-pigmented ciliary epithelial cells."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15106942"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tetrapyrrole metabolism" -- [pigmented ciliary epithelial cell](http://purl.obolibrary.org/obo/CL_0002303) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "PE"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" -- [pigmented ciliary epithelial cell](http://purl.obolibrary.org/obo/CL_0002303) SubClassOf [multi-ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_0005012) +- Class: [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) -#### Added -- [pigmented ciliary epithelial cell](http://purl.obolibrary.org/obo/CL_0002303) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "PE cell"^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://doi.org/10.1016/j.exer.2003.09.021"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932)) -- [pigmented ciliary epithelial cell](http://purl.obolibrary.org/obo/CL_0002303) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "In a consensus model of unidirectional secretion, aqueous humour is formed by transferring solute, principally NaCl, from stroma to posterior chamber, with water passively following the osmotic gradient. Unidirectional secretion comprises three sequential steps. First, NaCl is transferred from the stromal interstitium into the pigmented ciliary epithelial (PE) cells. Second, solute passes from the PE into the non-pigmented ciliary epithelial (NPE) cells through gap junctions. Finally, NPE cells release Na+ and Cl− into the aqueous humour."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://doi.org/10.1016/j.exer.2003.09.021"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) SubClassOf [cellular aromatic compound metabolic process](http://purl.obolibrary.org/obo/GO_0006725) -- [pigmented ciliary epithelial cell](http://purl.obolibrary.org/obo/CL_0002303) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A cell that is part of pigmented ciliary epithelium. This cell type uptakes sodium and chloride ions from stromal interstitium and passes the ions to non-pigmented ciliary epithelial cells via gap junctions."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15106942"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) SubClassOf [heterocycle metabolic process](http://purl.obolibrary.org/obo/GO_0046483) -- [pigmented ciliary epithelial cell](http://purl.obolibrary.org/obo/CL_0002303) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [ciliary epithelium](http://purl.obolibrary.org/obo/UBERON_0001778) +- [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) SubClassOf [organonitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_1901564) +- [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [tetrapyrrole](http://purl.obolibrary.org/obo/CHEBI_26932) -### pilosebaceous unit `http://purl.obolibrary.org/obo/UBERON_0011932` -#### Removed -- [pilosebaceous unit](http://purl.obolibrary.org/obo/UBERON_0011932) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [tetrapyrrole metabolic process](http://purl.obolibrary.org/obo/GO_0033013) SubClassOf [organic cyclic compound metabolic process](http://purl.obolibrary.org/obo/GO_1901360) -### polyphenol `http://purl.obolibrary.org/obo/CHEBI_26195` +### thoracic aorta smooth muscle tissue `http://purl.obolibrary.org/obo/UBERON_8480002` #### Removed -- [polyphenol](http://purl.obolibrary.org/obo/CHEBI_26195) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) +- [thoracic aorta smooth muscle tissue](http://purl.obolibrary.org/obo/UBERON_8480002) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](http://orcid.org/0000-0002-0819-0473) -- [polyphenol](http://purl.obolibrary.org/obo/CHEBI_26195) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:26195" - -- [polyphenol](http://purl.obolibrary.org/obo/CHEBI_26195) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "polyphenols" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" +#### Added +- [thoracic aorta smooth muscle tissue](http://purl.obolibrary.org/obo/UBERON_8480002) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-0819-0473](https://orcid.org/0000-0002-0819-0473) -- [polyphenol](http://purl.obolibrary.org/obo/CHEBI_26195) [label](http://www.w3.org/2000/01/rdf-schema#label) "polyphenol" -- [polyphenol](http://purl.obolibrary.org/obo/CHEBI_26195) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" +### thymic conventional dendritic cell `http://purl.obolibrary.org/obo/CL_0000941` +#### Removed +- [thymic conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000941) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [thymus](http://purl.obolibrary.org/obo/UBERON_0002370)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) -- [polyphenol](http://purl.obolibrary.org/obo/CHEBI_26195) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Members of the class of phenols that contain 2 or more benzene rings each of which is substituted by at least one hydroxy group." +- [thymic conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000941) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) -- [polyphenol](http://purl.obolibrary.org/obo/CHEBI_26195) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Polyphenol" +- [thymic conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000941) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) -- Class: [polyphenol](http://purl.obolibrary.org/obo/CHEBI_26195) +#### Added +- [thymic conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000941) EquivalentTo [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [thymus](http://purl.obolibrary.org/obo/UBERON_0002370)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [integrin alpha-X](http://purl.obolibrary.org/obo/PR_000001013)) -- [polyphenol](http://purl.obolibrary.org/obo/CHEBI_26195) SubClassOf [phenols](http://purl.obolibrary.org/obo/CHEBI_33853) +- [thymic conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000941) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015) +- [thymic conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000941) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) -### positive regulation of melanin biosynthetic process `http://purl.obolibrary.org/obo/GO_0048023` +### thymic plasmacytoid dendritic cell `http://purl.obolibrary.org/obo/CL_0000942` #### Removed -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jid" +- [thymic plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000942) EquivalentTo [plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000784) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of melanin biosynthetic process" +- [thymic plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000942) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of melanin anabolism" +#### Added +- [thymic plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000942) EquivalentTo [plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000784) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [receptor-type tyrosine-protein phosphatase C isoform CD45RA](http://purl.obolibrary.org/obo/PR_000001015)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [interleukin-3 receptor class 2 alpha chain](http://purl.obolibrary.org/obo/PR_000001865)) -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of melanin biosynthetic process" +- [thymic plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000942) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012) -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "stimulation of melanin biosynthetic process" -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of melanin synthesis" +### thymocyte `http://purl.obolibrary.org/obo/CL_0000893` +#### Removed +- [thymocyte](http://purl.obolibrary.org/obo/CL_0000893) EquivalentTo [T cell](http://purl.obolibrary.org/obo/CL_0000084) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [thymus](http://purl.obolibrary.org/obo/UBERON_0002370)) and ([has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0048023" +#### Added +- [thymocyte](http://purl.obolibrary.org/obo/CL_0000893) EquivalentTo [T cell](http://purl.obolibrary.org/obo/CL_0000084) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [thymus](http://purl.obolibrary.org/obo/UBERON_0002370)) and ([has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [T cell selection](http://purl.obolibrary.org/obo/GO_0045058)) -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of melanin formation" +### title `http://purl.org/dc/terms/title` -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of melanin biosynthetic process" +#### Added +- AnnotationProperty: [title](http://purl.org/dc/terms/title) -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of melanin biosynthetic process" -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of melanin biosynthesis" +### touch receptor cell `http://purl.obolibrary.org/obo/CL_0000200` -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) [has_narrow_synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of melanin biosynthetic process" +#### Added +- [touch receptor cell](http://purl.obolibrary.org/obo/CL_0000200) SubClassOf [somatosensory neuron](http://purl.obolibrary.org/obo/CL_4023168) -- Class: [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) +- [touch receptor cell](http://purl.obolibrary.org/obo/CL_0000200) SubClassOf [neuronal receptor cell](http://purl.obolibrary.org/obo/CL_0000006) -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438)) -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) +### tracheal epithelial cell `http://purl.obolibrary.org/obo/CL_0000307` +#### Removed +- [tracheal epithelial cell](http://purl.obolibrary.org/obo/CL_0000307) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000474" -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) SubClassOf [positive regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031328) -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) SubClassOf [regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048021) -- [positive regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048023) SubClassOf [positive regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900378) +### trans-synaptic signaling, modulating synaptic transmission `http://purl.obolibrary.org/obo/GO_0099550` +#### Removed +- [trans-synaptic signaling, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099550) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [chemical synaptic transmission](http://purl.obolibrary.org/obo/GO_0007268) +#### Added +- [trans-synaptic signaling, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099550) SubClassOf [modulation of chemical synaptic transmission](http://purl.obolibrary.org/obo/GO_0050804) -### pre-B-II cell `http://purl.obolibrary.org/obo/CL_0000955` +### transepithelial ammonium transport `http://purl.obolibrary.org/obo/GO_0070634` #### Removed -- [pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000955) EquivalentTo [precursor B cell](http://purl.obolibrary.org/obo/CL_0000817) and ([has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [immunoglobulin heavy chain V-D-J recombination](http://purl.obolibrary.org/obo/GO_0071707)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [DNA nucleotidylexotransferase](http://purl.obolibrary.org/obo/PR_000006611)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) +- [transepithelial ammonium transport](http://purl.obolibrary.org/obo/GO_0070634) SubClassOf [nitrogen compound transport](http://purl.obolibrary.org/obo/GO_0071705) -- [pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000955) SubClassOf [has_completed](http://purl.obolibrary.org/obo/cl#has_completed) some [immunoglobulin heavy chain V-D-J recombination](http://purl.obolibrary.org/obo/GO_0071707) -#### Added -- [pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000955) EquivalentTo [precursor B cell](http://purl.obolibrary.org/obo/CL_0000817) and ([output of](http://purl.obolibrary.org/obo/RO_0002353) some [immunoglobulin heavy chain V-D-J recombination](http://purl.obolibrary.org/obo/GO_0071707)) and ([lacks_part](http://purl.obolibrary.org/obo/cl#lacks_part) some [DNA nucleotidylexotransferase](http://purl.obolibrary.org/obo/PR_000006611)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [CD34 molecule](http://purl.obolibrary.org/obo/PR_000001003)) -- [pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000955) SubClassOf [output of](http://purl.obolibrary.org/obo/RO_0002353) some [immunoglobulin heavy chain V-D-J recombination](http://purl.obolibrary.org/obo/GO_0071707) +### transformation of `http://purl.obolibrary.org/obo/RO_0002494` +#### Removed +- [transformation of](http://purl.obolibrary.org/obo/RO_0002494) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" +#### Added +- [transformation of](http://purl.obolibrary.org/obo/RO_0002494) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) -### processual entity `http://purl.obolibrary.org/obo/UBERON_0000000` -#### Added -- [processual entity](http://purl.obolibrary.org/obo/UBERON_0000000) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) +### transition element atom `http://purl.obolibrary.org/obo/CHEBI_27081` +#### Removed +- [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "transition metal" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [processual entity](http://purl.obolibrary.org/obo/UBERON_0000000) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metales de transicion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [processual entity](http://purl.obolibrary.org/obo/UBERON_0000000) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Uebergangsmetalle" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [processual entity](http://purl.obolibrary.org/obo/UBERON_0000000) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:27081" +- [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell." -### prostate luminal epithelium `http://purl.obolibrary.org/obo/UBERON_0011951` +- [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) [label](http://www.w3.org/2000/01/rdf-schema#label) "transition element atom" -#### Added -- [prostate luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011951) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A luminal layer of epithelium that is part of a prostate gland." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [prostate luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011951) [label](http://www.w3.org/2000/01/rdf-schema#label) "prostate luminal epithelium" +- [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [prostate luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011951) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74262" +- [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metal de transicion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [prostate luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011951) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "subdivision of luminal layer of epithelium of prostatic gland" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74262" +- [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "transition element" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [prostate luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011951) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0011951" +- [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Uebergangselement" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [prostate luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011951) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "transition elements" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- Class: [prostate luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011951) +- [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metaux de transition" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [prostate luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011951) EquivalentTo [luminal layer of epithelium](http://purl.obolibrary.org/obo/UBERON_0011945) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [prostate gland](http://purl.obolibrary.org/obo/UBERON_0002367)) +- [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metal de transition" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [prostate luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011951) SubClassOf [luminal layer of epithelium](http://purl.obolibrary.org/obo/UBERON_0011945) +- [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "transition metals" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [prostate luminal epithelium](http://purl.obolibrary.org/obo/UBERON_0011951) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [prostate epithelium](http://purl.obolibrary.org/obo/UBERON_0000428) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships" +- [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "transition element" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" - - [is_inferred](http://www.geneontology.org/formats/oboInOwl#is_inferred) "true" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) +- Class: [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) -### pulmonary artery `http://purl.obolibrary.org/obo/UBERON_0002012` -#### Removed -- [pulmonary artery](http://purl.obolibrary.org/obo/UBERON_0002012) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) SubClassOf [metal atom](http://purl.obolibrary.org/obo/CHEBI_33521) -### pulmonary vascular system `http://purl.obolibrary.org/obo/UBERON_0008886` +### transition element cation `http://purl.obolibrary.org/obo/CHEBI_33515` #### Removed -- [pulmonary vascular system](http://purl.obolibrary.org/obo/UBERON_0008886) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [transition element cation](http://purl.obolibrary.org/obo/CHEBI_33515) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) +- [transition element cation](http://purl.obolibrary.org/obo/CHEBI_33515) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33515" +- [transition element cation](http://purl.obolibrary.org/obo/CHEBI_33515) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -### pulmonary vein `http://purl.obolibrary.org/obo/UBERON_0002016` -#### Removed -- [pulmonary vein](http://purl.obolibrary.org/obo/UBERON_0002016) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [transition element cation](http://purl.obolibrary.org/obo/CHEBI_33515) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "transition element cations" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" +- [transition element cation](http://purl.obolibrary.org/obo/CHEBI_33515) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "transition metal cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" +- [transition element cation](http://purl.obolibrary.org/obo/CHEBI_33515) [label](http://www.w3.org/2000/01/rdf-schema#label) "transition element cation" -### recurrent laryngeal nerve `http://purl.obolibrary.org/obo/UBERON_0003716` -#### Removed -- [recurrent laryngeal nerve](http://purl.obolibrary.org/obo/UBERON_0003716) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- Class: [transition element cation](http://purl.obolibrary.org/obo/CHEBI_33515) +- [transition element cation](http://purl.obolibrary.org/obo/CHEBI_33515) SubClassOf [metal cation](http://purl.obolibrary.org/obo/CHEBI_25213) -### regulation of melanin biosynthetic process `http://purl.obolibrary.org/obo/GO_0048021` -#### Removed -- [regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048021) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0048021" -- [regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048021) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of melanin synthesis" +### transition element molecular entity `http://purl.obolibrary.org/obo/CHEBI_33497` +#### Removed +- [transition element molecular entity](http://purl.obolibrary.org/obo/CHEBI_33497) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048021) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" +- [transition element molecular entity](http://purl.obolibrary.org/obo/CHEBI_33497) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "transition element molecular entities" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048021) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of melanin anabolism" +- [transition element molecular entity](http://purl.obolibrary.org/obo/CHEBI_33497) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048021) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of melanin formation" +- [transition element molecular entity](http://purl.obolibrary.org/obo/CHEBI_33497) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A molecular entity containing one or more atoms of a transition element." -- [regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048021) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of melanin biosynthetic process" +- [transition element molecular entity](http://purl.obolibrary.org/obo/CHEBI_33497) [label](http://www.w3.org/2000/01/rdf-schema#label) "transition element molecular entity" -- [regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048021) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of melanin biosynthesis" +- [transition element molecular entity](http://purl.obolibrary.org/obo/CHEBI_33497) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "transition metal molecular entity" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048021) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jid" +- [transition element molecular entity](http://purl.obolibrary.org/obo/CHEBI_33497) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:33497" -- Class: [regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048021) +- Class: [transition element molecular entity](http://purl.obolibrary.org/obo/CHEBI_33497) -- [regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048021) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438)) +- [transition element molecular entity](http://purl.obolibrary.org/obo/CHEBI_33497) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [transition element atom](http://purl.obolibrary.org/obo/CHEBI_27081) -- [regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048021) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0042438) +- [transition element molecular entity](http://purl.obolibrary.org/obo/CHEBI_33497) SubClassOf [molecular entity](http://purl.obolibrary.org/obo/CHEBI_23367) -- [regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048021) SubClassOf [regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031326) -- [regulation of melanin biosynthetic process](http://purl.obolibrary.org/obo/GO_0048021) SubClassOf [regulation of secondary metabolite biosynthetic process](http://purl.obolibrary.org/obo/GO_1900376) +### transition metal ion binding `http://purl.obolibrary.org/obo/GO_0046914` +#### Removed +- [transition metal ion binding](http://purl.obolibrary.org/obo/GO_0046914) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" +- [transition metal ion binding](http://purl.obolibrary.org/obo/GO_0046914) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046914" -### regulation of stomach neuroendocrine cell differentiation `http://purl.obolibrary.org/obo/GO_0061105` +- [transition metal ion binding](http://purl.obolibrary.org/obo/GO_0046914) [label](http://www.w3.org/2000/01/rdf-schema#label) "transition metal ion binding" -#### Added -- [regulation of stomach neuroendocrine cell differentiation](http://purl.obolibrary.org/obo/GO_0061105) SubClassOf [regulation of neuron differentiation](http://purl.obolibrary.org/obo/GO_0045664) +- [transition metal ion binding](http://purl.obolibrary.org/obo/GO_0046914) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" +- Class: [transition metal ion binding](http://purl.obolibrary.org/obo/GO_0046914) -### respiratory ciliated cell `http://purl.obolibrary.org/obo/CL_4030034` +- [transition metal ion binding](http://purl.obolibrary.org/obo/GO_0046914) EquivalentTo [binding](http://purl.obolibrary.org/obo/GO_0005488) and ([has input](http://purl.obolibrary.org/obo/RO_0002233) some [transition element cation](http://purl.obolibrary.org/obo/CHEBI_33515)) -#### Added -- [respiratory ciliated cell](http://purl.obolibrary.org/obo/CL_4030034) [date](http://purl.org/dc/terms/date) "2023-01-25T11:06:01Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) +- [transition metal ion binding](http://purl.obolibrary.org/obo/GO_0046914) SubClassOf [metal ion binding](http://purl.obolibrary.org/obo/GO_0046872) -- [respiratory ciliated cell](http://purl.obolibrary.org/obo/CL_4030034) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ciliated cell of the respiratory tract"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [transition metal ion binding](http://purl.obolibrary.org/obo/GO_0046914) SubClassOf [has input](http://purl.obolibrary.org/obo/RO_0002233) some [transition element cation](http://purl.obolibrary.org/obo/CHEBI_33515) -- [respiratory ciliated cell](http://purl.obolibrary.org/obo/CL_4030034) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A ciliated cell of the respiratory system. Ciliated cells are present in airway epithelium."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18757316"^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:21364219"^^[string](http://www.w3.org/2001/XMLSchema#string) -- [respiratory ciliated cell](http://purl.obolibrary.org/obo/CL_4030034) [label](http://www.w3.org/2000/01/rdf-schema#label) "respiratory ciliated cell" +### transition metal ion transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0046915` +#### Removed +- [transition metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046915) [label](http://www.w3.org/2000/01/rdf-schema#label) "transition metal ion transmembrane transporter activity" -- Class: [respiratory ciliated cell](http://purl.obolibrary.org/obo/CL_4030034) +- [transition metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046915) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" -- [respiratory ciliated cell](http://purl.obolibrary.org/obo/CL_4030034) EquivalentTo [ciliated cell](http://purl.obolibrary.org/obo/CL_0000064) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [respiratory tract epithelium](http://purl.obolibrary.org/obo/UBERON_0004802)) +- [transition metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046915) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046915" -- [respiratory ciliated cell](http://purl.obolibrary.org/obo/CL_4030034) SubClassOf [ciliated cell](http://purl.obolibrary.org/obo/CL_0000064) +- [transition metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046915) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" -- [respiratory ciliated cell](http://purl.obolibrary.org/obo/CL_4030034) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) +- Class: [transition metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046915) -- [respiratory ciliated cell](http://purl.obolibrary.org/obo/CL_4030034) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [respiratory tract epithelium](http://purl.obolibrary.org/obo/UBERON_0004802) +- [transition metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046915) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [transition element cation](http://purl.obolibrary.org/obo/CHEBI_33515)) +- [transition metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046915) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [transition metal ion transport](http://purl.obolibrary.org/obo/GO_0000041) -### right lung bronchiole `http://purl.obolibrary.org/obo/UBERON_0003538` -#### Removed -- [right lung bronchiole](http://purl.obolibrary.org/obo/UBERON_0003538) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobular bronchiole of right lung" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [transition metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046915) SubClassOf [metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046873) -- [right lung bronchiole](http://purl.obolibrary.org/obo/UBERON_0003538) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "right lung lobular bronchiole" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [transition metal ion transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0046915) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [transition element cation](http://purl.obolibrary.org/obo/CHEBI_33515) -### rostral periventricular region of the third ventricle KDNy neuron `http://purl.obolibrary.org/obo/CL_4023128` +### transition metal ion transport `http://purl.obolibrary.org/obo/GO_0000041` #### Removed -- [rostral periventricular region of the third ventricle KDNy neuron](http://purl.obolibrary.org/obo/CL_4023128) [label](http://www.w3.org/2000/01/rdf-schema#label) "rostral periventricular region of the third ventricle KDNy neuron" +- [transition metal ion transport](http://purl.obolibrary.org/obo/GO_0000041) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" -- [rostral periventricular region of the third ventricle KDNy neuron](http://purl.obolibrary.org/obo/CL_4023128) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "RP3V KDNy neuron" +- [transition metal ion transport](http://purl.obolibrary.org/obo/GO_0000041) [label](http://www.w3.org/2000/01/rdf-schema#label) "transition metal ion transport" -- [rostral periventricular region of the third ventricle KDNy neuron](http://purl.obolibrary.org/obo/CL_4023128) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "a KDNy neuron that is located in the rostral periventricular region of the third ventricle." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WikipediaVersioned:KNDy_neuron&oldid=964682278"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [transition metal ion transport](http://purl.obolibrary.org/obo/GO_0000041) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0000041" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30042117"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [transition metal ion transport](http://purl.obolibrary.org/obo/GO_0000041) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" -#### Added -- [rostral periventricular region of the third ventricle KDNy neuron](http://purl.obolibrary.org/obo/CL_4023128) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "a KNDy neuron that is located in the rostral periventricular region of the third ventricle."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "WikipediaVersioned:KNDy_neuron&oldid=964682278"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [transition metal ion transport](http://purl.obolibrary.org/obo/GO_0000041) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "transition metal transport" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30042117"^^[string](http://www.w3.org/2001/XMLSchema#string) +- Class: [transition metal ion transport](http://purl.obolibrary.org/obo/GO_0000041) -- [rostral periventricular region of the third ventricle KDNy neuron](http://purl.obolibrary.org/obo/CL_4023128) [label](http://www.w3.org/2000/01/rdf-schema#label) "rostral periventricular region of the third ventricle KNDy neuron"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [transition metal ion transport](http://purl.obolibrary.org/obo/GO_0000041) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [transition element cation](http://purl.obolibrary.org/obo/CHEBI_33515)) -- [rostral periventricular region of the third ventricle KDNy neuron](http://purl.obolibrary.org/obo/CL_4023128) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "RP3V KNDy neuron"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [transition metal ion transport](http://purl.obolibrary.org/obo/GO_0000041) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [transition element cation](http://purl.obolibrary.org/obo/CHEBI_33515) +- [transition metal ion transport](http://purl.obolibrary.org/obo/GO_0000041) SubClassOf [metal ion transport](http://purl.obolibrary.org/obo/GO_0030001) -### serous cell of epithelium of lobular bronchiole `http://purl.obolibrary.org/obo/CL_1000333` -#### Removed -- [serous cell of epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/CL_1000333) EquivalentTo [serous secreting cell](http://purl.obolibrary.org/obo/CL_0000313) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of bronchiole](http://purl.obolibrary.org/obo/UBERON_0002051)) -- [serous cell of epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/CL_1000333) SubClassOf [serous cell of epithelium of bronchus](http://purl.obolibrary.org/obo/CL_1000331) -- [serous cell of epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/CL_1000333) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of bronchiole](http://purl.obolibrary.org/obo/UBERON_0002051) +### transitional myocyte of atrioventricular bundle `http://purl.obolibrary.org/obo/CL_1000481` #### Added -- [serous cell of epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/CL_1000333) EquivalentTo [serous secreting cell](http://purl.obolibrary.org/obo/CL_0000313) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001)) - -- [serous cell of epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/CL_1000333) SubClassOf [tracheobronchial serous cell](http://purl.obolibrary.org/obo/CL_0019001) - -- [serous cell of epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/CL_1000333) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600001) +- [transitional myocyte of atrioventricular bundle](http://purl.obolibrary.org/obo/CL_1000481) SubClassOf [transversely striated visceral muscle cell](http://purl.obolibrary.org/obo/CL_0008009) -### serous cell of epithelium of terminal bronchiole `http://purl.obolibrary.org/obo/CL_1000332` +### transitional stage B cell `http://purl.obolibrary.org/obo/CL_0000818` #### Removed -- [serous cell of epithelium of terminal bronchiole](http://purl.obolibrary.org/obo/CL_1000332) SubClassOf [serous cell of epithelium of lobular bronchiole](http://purl.obolibrary.org/obo/CL_1000333) +- [transitional stage B cell](http://purl.obolibrary.org/obo/CL_0000818) EquivalentTo [B cell, CD19-positive](http://purl.obolibrary.org/obo/CL_0001201) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [mature B cell differentiation](http://purl.obolibrary.org/obo/GO_0002335)) -#### Added -- [serous cell of epithelium of terminal bronchiole](http://purl.obolibrary.org/obo/CL_1000332) SubClassOf [lung secretory cell](http://purl.obolibrary.org/obo/CL_1000272) - -- [serous cell of epithelium of terminal bronchiole](http://purl.obolibrary.org/obo/CL_1000332) SubClassOf [tracheobronchial serous cell](http://purl.obolibrary.org/obo/CL_0019001) - - -### serous secreting cell of bronchus submucosal gland `http://purl.obolibrary.org/obo/CL_4033005` +- [transitional stage B cell](http://purl.obolibrary.org/obo/CL_0000818) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/cl#has_not_completed) some [mature B cell differentiation](http://purl.obolibrary.org/obo/GO_0002335) #### Added -- [serous secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033005) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A(n) serous secreting cell that is part of a(n) bronchus submucosal gland."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9651178"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [transitional stage B cell](http://purl.obolibrary.org/obo/CL_0000818) EquivalentTo [B cell, CD19-positive](http://purl.obolibrary.org/obo/CL_0001201) and ([has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [mature B cell differentiation](http://purl.obolibrary.org/obo/GO_0002335)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1](http://purl.obolibrary.org/obo/PR_000001408)) and ([has high plasma membrane amount](http://purl.obolibrary.org/obo/RO_0015015) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:5487122"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [transitional stage B cell](http://purl.obolibrary.org/obo/CL_0000818) SubClassOf [has_not_completed](http://purl.obolibrary.org/obo/CL_4030044) some [mature B cell differentiation](http://purl.obolibrary.org/obo/GO_0002335) -- [serous secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033005) [label](http://www.w3.org/2000/01/rdf-schema#label) "serous secreting cell of bronchus submucosal gland"^^[string](http://www.w3.org/2001/XMLSchema#string) -- [serous secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033005) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) +### translation `http://purl.obolibrary.org/obo/GO_0006412` +#### Removed +- [translation](http://purl.obolibrary.org/obo/GO_0006412) SubClassOf [peptide biosynthetic process](http://purl.obolibrary.org/obo/GO_0043043) -- Class: [serous secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033005) +- [translation](http://purl.obolibrary.org/obo/GO_0006412) SubClassOf [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) -- [serous secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033005) EquivalentTo [serous secreting cell](http://purl.obolibrary.org/obo/CL_0000313) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [bronchus submucosal gland](http://purl.obolibrary.org/obo/UBERON_8410043)) +#### Added +- [translation](http://purl.obolibrary.org/obo/GO_0006412) SubClassOf [macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0009059) -- [serous secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033005) SubClassOf [tracheobronchial serous cell](http://purl.obolibrary.org/obo/CL_0019001) -- [serous secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033005) SubClassOf [exocrine cell](http://purl.obolibrary.org/obo/CL_0000152) +### translational elongation `http://purl.obolibrary.org/obo/GO_0006414` +#### Removed +- [translational elongation](http://purl.obolibrary.org/obo/GO_0006414) SubClassOf [cellular macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0034645) -- [serous secreting cell of bronchus submucosal gland](http://purl.obolibrary.org/obo/CL_4033005) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [bronchus submucosal gland](http://purl.obolibrary.org/obo/UBERON_8410043) +#### Added +- [translational elongation](http://purl.obolibrary.org/obo/GO_0006414) SubClassOf [macromolecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0009059) -### sialic acid-binding Ig-like lectin 5 (mouse) `http://purl.obolibrary.org/obo/PR_Q920G3` +### tributary of `http://purl.obolibrary.org/obo/RO_0002376` +#### Removed +- [tributary of](http://purl.obolibrary.org/obo/RO_0002376) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) "Chris Mungall" #### Added -- [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "CD170 (mouse)" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:Q920G3" - -- [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sialic acid-binding Ig-like lectin F (mouse)" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:Q920G3" +- [tributary of](http://purl.obolibrary.org/obo/RO_0002376) [IAO_0000117](http://purl.obolibrary.org/obo/IAO_0000117) [0000-0002-6601-2165](https://orcid.org/0000-0002-6601-2165) -- [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:Q920G3" -- [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Siglec5" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:Q920G3" +### triterpene `http://purl.obolibrary.org/obo/CHEBI_35191` +#### Removed +- [triterpene](http://purl.obolibrary.org/obo/CHEBI_35191) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "triterpenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [Gene-based](http://purl.obolibrary.org/obo/pr#Gene-based) +- [triterpene](http://purl.obolibrary.org/obo/CHEBI_35191) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "triterpenos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Siglecf" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:Q920G3" +- [triterpene](http://purl.obolibrary.org/obo/CHEBI_35191) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [Gene-based](http://purl.obolibrary.org/obo/pr#Gene-based) +- [triterpene](http://purl.obolibrary.org/obo/CHEBI_35191) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "mSiglec-F" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:Q920G3" +- [triterpene](http://purl.obolibrary.org/obo/CHEBI_35191) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "triterpenes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "siglec-5 (mouse)" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:Q920G3" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) [id](http://www.geneontology.org/formats/oboInOwl#id) "PR:Q920G3" +- [triterpene](http://purl.obolibrary.org/obo/CHEBI_35191) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35191" -- [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) [label](http://www.w3.org/2000/01/rdf-schema#label) "sialic acid-binding Ig-like lectin 5 (mouse)" +- [triterpene](http://purl.obolibrary.org/obo/CHEBI_35191) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "triterpeno" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "siglec-F (mouse)" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:Q920G3" +- [triterpene](http://purl.obolibrary.org/obo/CHEBI_35191) [label](http://www.w3.org/2000/01/rdf-schema#label) "triterpene" -- [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Category=organism-gene." +- [triterpene](http://purl.obolibrary.org/obo/CHEBI_35191) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Triterpen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "mSIGLEC6" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [PRO-short-label](http://purl.obolibrary.org/obo/pr#PRO-short-label) +- [triterpene](http://purl.obolibrary.org/obo/CHEBI_35191) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A C30 terpene." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:DNx" +- Class: [triterpene](http://purl.obolibrary.org/obo/CHEBI_35191) -- [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "protein" +- [triterpene](http://purl.obolibrary.org/obo/CHEBI_35191) SubClassOf [terpene](http://purl.obolibrary.org/obo/CHEBI_35186) -- [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A sialic acid-binding Ig-like lectin 6 that is encoded in the genome of mouse." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:WCB" -- Class: [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) -- [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) EquivalentTo [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) and ([only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090)) +### trivalent inorganic anion `http://purl.obolibrary.org/obo/CHEBI_79387` +#### Removed +- [trivalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79387) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:79387" -- [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) SubClassOf [Mus musculus protein](http://purl.obolibrary.org/obo/PR_000029032) +- [trivalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79387) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trivalent inorganic anions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [sialic acid-binding Ig-like lectin 5 (mouse)](http://purl.obolibrary.org/obo/PR_Q920G3) SubClassOf [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) +- [trivalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79387) [label](http://www.w3.org/2000/01/rdf-schema#label) "trivalent inorganic anion" +- [trivalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79387) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -### sialic acid-binding Ig-like lectin 6 `http://purl.obolibrary.org/obo/PR_000001928` +- [trivalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79387) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any inorganic anion with a valency of three." -#### Added -- [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) [id](http://www.geneontology.org/formats/oboInOwl#id) "PR:000001928" +- [trivalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79387) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "CD33 antigen-like 1" +- Class: [trivalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79387) -- [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "OBBP1" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [Gene-based](http://purl.obolibrary.org/obo/pr#Gene-based) +- [trivalent inorganic anion](http://purl.obolibrary.org/obo/CHEBI_79387) SubClassOf [inorganic anion](http://purl.obolibrary.org/obo/CHEBI_24834) -- [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Category=gene. There is no mouse ortholog." -- [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CD33L" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [Gene-based](http://purl.obolibrary.org/obo/pr#Gene-based) -- [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "siglec-6" +### trophoblast giant cell `http://purl.obolibrary.org/obo/CL_0002488` +#### Removed +- [trophoblast giant cell](http://purl.obolibrary.org/obo/CL_0002488) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) -- [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "protein" -- [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "obesity-binding protein 1" -- [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "SIGLEC6" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [PRO-short-label](http://purl.obolibrary.org/obo/pr#PRO-short-label) +### tryptamine `http://purl.obolibrary.org/obo/CHEBI_16765` +#### Removed +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22770225" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:DNx" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:125513" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" -- [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "OB-BP1" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [mass](http://purl.obolibrary.org/obo/chebi/mass) "160.21570" -- [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CD33L1" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [Gene-based](http://purl.obolibrary.org/obo/pr#Gene-based) +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2" -- [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "CD327" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "2-(1H-INDOL-3-YL)ETHANAMINE" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" -- [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A protein that is a translation product of the human SIGLEC6 gene or a 1:1 ortholog thereof." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:WCB" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DrugBank:DB08653" -- [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) [label](http://www.w3.org/2000/01/rdf-schema#label) "sialic acid-binding Ig-like lectin 6" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:46157" -- [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "CDw327" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:125513" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" -- Class: [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:16126914" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) SubClassOf [protein](http://purl.obolibrary.org/obo/PR_000000001) +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "2-(1H-indol-3-yl)ethanamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) SubClassOf [protein](http://purl.obolibrary.org/obo/CHEBI_36080) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:61-54-1" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" -### sialic acid-binding Ig-like lectin 6 (human) `http://purl.obolibrary.org/obo/PR_O43699` +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:27161" -#### Added -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) [label](http://www.w3.org/2000/01/rdf-schema#label) "sialic acid-binding Ig-like lectin 6 (human)" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "2-(3-indolyl)ethylamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CD33L1" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:O43699" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Tryptamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [Gene-based](http://purl.obolibrary.org/obo/pr#Gene-based) +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "CD327 (human)" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:O43699" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "1H-indole-3-ethanamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NIST_Chemistry_WebBook" -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Category=organism-gene." +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24558969" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "CD33 antigen-like 1 (human)" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:O43699" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:16765" -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "SIGLEC6" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:O43699" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "3-(2-Aminoethyl)indole" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [Gene-based](http://purl.obolibrary.org/obo/pr#Gene-based) +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [label](http://www.w3.org/2000/01/rdf-schema#label) "tryptamine" -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "OB-BP1 (human)" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:O43699" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C10H12N2" -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "obesity-binding protein 1 (human)" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:O43699" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position." -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A sialic acid-binding Ig-like lectin 6 that is encoded in the genome of human." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:O43699" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:TRYPTAMINE" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:WCB" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00398" -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) [id](http://www.geneontology.org/formats/oboInOwl#id) "PR:O43699" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:15274" -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "protein" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "OBBP1" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:O43699" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0000303" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [Gene-based](http://purl.obolibrary.org/obo/pr#Gene-based) +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "160.10005" -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hSIGLEC6" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [PRO-short-label](http://purl.obolibrary.org/obo/pr#PRO-short-label) +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24345948" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:DNx" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:TSS" -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "CDw327 (human)" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:O43699" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "NCCc1c[nH]c2ccccc12" -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "siglec-6 (human)" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:O43699" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tryptamine" -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:O43699" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:9767" -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CD33L" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:O43699" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:61-54-1" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [Gene-based](http://purl.obolibrary.org/obo/pr#Gene-based) +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:61-54-1" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" -- Class: [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KNApSAcK:C00001434" -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) EquivalentTo [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) and ([only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "APJYDQYYACXCRM-UHFFFAOYSA-N" -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) SubClassOf [Homo sapiens protein](http://purl.obolibrary.org/obo/PR_000029067) +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:603448" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" -- [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) SubClassOf [sialic acid-binding Ig-like lectin 6](http://purl.obolibrary.org/obo/PR_000001928) +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" +- Class: [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) -### sialic acid-binding Ig-like lectin 6, signal peptide removed form (human) `http://purl.obolibrary.org/obo/PR_000049246` +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) -#### Added -- [sialic acid-binding Ig-like lectin 6, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000049246) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-197708" - - [label](http://www.w3.org/2000/01/rdf-schema#label) "PR:000049246 located_in GO:0005886" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) SubClassOf [tryptamines](http://purl.obolibrary.org/obo/CHEBI_27162) -- [sialic acid-binding Ig-like lectin 6, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000049246) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Category=organism-modification." +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) SubClassOf [aralkylamino compound](http://purl.obolibrary.org/obo/CHEBI_64365) -- [sialic acid-binding Ig-like lectin 6, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000049246) [id](http://www.geneontology.org/formats/oboInOwl#id) "PR:000049246" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [plant metabolite](http://purl.obolibrary.org/obo/CHEBI_76924) -- [sialic acid-binding Ig-like lectin 6, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000049246) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "UniProtKB:O43699, 27-453" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:DNx" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [PRO-proteoform-std](http://purl.obolibrary.org/obo/pr#PRO-proteoform-std) +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) -- [sialic acid-binding Ig-like lectin 6, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000049246) [label](http://www.w3.org/2000/01/rdf-schema#label) "sialic acid-binding Ig-like lectin 6, signal peptide removed form (human)" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) SubClassOf [aminoalkylindole](http://purl.obolibrary.org/obo/CHEBI_38631) -- [sialic acid-binding Ig-like lectin 6, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000049246) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A sialic acid-binding Ig-like lectin 6 (human) that has had the signal peptide removed. UniProtKB:O43699, 27-453." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:DNx" +- [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) SubClassOf [indole alkaloid](http://purl.obolibrary.org/obo/CHEBI_38958) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-197708" -- [sialic acid-binding Ig-like lectin 6, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000049246) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "protein" -- [sialic acid-binding Ig-like lectin 6, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000049246) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hSIGLEC6/SigPep-" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [PRO-short-label](http://purl.obolibrary.org/obo/pr#PRO-short-label) +### tryptamines `http://purl.obolibrary.org/obo/CHEBI_27162` +#### Removed +- [tryptamines](http://purl.obolibrary.org/obo/CHEBI_27162) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:DNx" +- [tryptamines](http://purl.obolibrary.org/obo/CHEBI_27162) [label](http://www.w3.org/2000/01/rdf-schema#label) "tryptamines" -- [sialic acid-binding Ig-like lectin 6, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000049246) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "PRO_0000014946" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:DNx" +- [tryptamines](http://purl.obolibrary.org/obo/CHEBI_27162) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [PRO-proteoform-ftid](http://purl.obolibrary.org/obo/pr#PRO-proteoform-ftid) +- [tryptamines](http://purl.obolibrary.org/obo/CHEBI_27162) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Tryptamine and its substitution derivatives." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ANON:ANON" -- Class: [sialic acid-binding Ig-like lectin 6, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000049246) +- [tryptamines](http://purl.obolibrary.org/obo/CHEBI_27162) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:27162" -- [sialic acid-binding Ig-like lectin 6, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000049246) EquivalentTo [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) and ([lacks_part](http://purl.obolibrary.org/obo/pr#lacks_part) some [SO_0000418](http://purl.obolibrary.org/obo/SO_0000418)) +- Class: [tryptamines](http://purl.obolibrary.org/obo/CHEBI_27162) -- [sialic acid-binding Ig-like lectin 6, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000049246) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/pr#lacks_part) some [SO_0000418](http://purl.obolibrary.org/obo/SO_0000418) +- [tryptamines](http://purl.obolibrary.org/obo/CHEBI_27162) SubClassOf [indoles](http://purl.obolibrary.org/obo/CHEBI_24828) -- [sialic acid-binding Ig-like lectin 6, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000049246) SubClassOf [sialic acid-binding Ig-like lectin 6 (human)](http://purl.obolibrary.org/obo/PR_O43699) -### small intestine smooth muscle circular layer `http://purl.obolibrary.org/obo/UBERON_0012401` +### tryptaminium `http://purl.obolibrary.org/obo/CHEBI_57887` +#### Removed +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[NH3+]CCc1c[nH]c2ccccc12" -#### Added -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "short pitch helicoidal muscle layer of small intestine" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14935" +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tryptaminium(1+)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "circular muscle coat of small intestine" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14935" +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) [mass](http://purl.obolibrary.org/obo/chebi/mass) "161.22310" -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum circulare tunicae muscularis intestini tenuis" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14935" +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:533978" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "161.10732" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "2-(1H-indol-3-yl)ethanaminium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14935" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "circular muscle layer of small intestine" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14935" +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) [label](http://www.w3.org/2000/01/rdf-schema#label) "tryptaminium" -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EMAPA:37562" - - [source](http://www.geneontology.org/formats/oboInOwl#source) "MA:th" +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "SCTID:54658003" +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:57887" -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "circular layer of small intestine muscularis propria" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14935" +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) [charge](http://purl.obolibrary.org/obo/chebi/charge) "+1" -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A circular muscle layer of muscular coat that is part of a small intestine smooth muscle." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3." -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2/p+1" -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "circular muscle of small intestine" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14935" +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tryptamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum circulare (tunica muscularis)(intestinum tenue)" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14935" +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "APJYDQYYACXCRM-UHFFFAOYSA-O" -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MA:0001560" +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum helicoidale brevis gradus tunicae muscularis intestini tenuis" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C10H13N2" -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [label](http://www.w3.org/2000/01/rdf-schema#label) "small intestine smooth muscle circular layer" +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tryptaminium cation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0012401" +- Class: [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) -- Class: [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) EquivalentTo [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [small intestine smooth muscle](http://purl.obolibrary.org/obo/UBERON_0004239)) +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [plant metabolite](http://purl.obolibrary.org/obo/CHEBI_76924) -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [small intestine smooth muscle](http://purl.obolibrary.org/obo/UBERON_0004239) +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [tryptamine](http://purl.obolibrary.org/obo/CHEBI_16765) -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [muscle layer of small intestine](http://purl.obolibrary.org/obo/UBERON_0011201) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) -- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) SubClassOf [circular muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012368) +- [tryptaminium](http://purl.obolibrary.org/obo/CHEBI_57887) SubClassOf [primary ammonium ion](http://purl.obolibrary.org/obo/CHEBI_65296) -### small intestine smooth muscle longitudinal layer `http://purl.obolibrary.org/obo/UBERON_0012402` -#### Added -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EMAPA:37563" - - [source](http://www.geneontology.org/formats/oboInOwl#source) "MA:th" +### type B pancreatic cell `http://purl.obolibrary.org/obo/CL_0000169` +#### Removed +- [type B pancreatic cell](http://purl.obolibrary.org/obo/CL_0000169) SubClassOf [epithelial cell of pancreas](http://purl.obolibrary.org/obo/CL_0000083) -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "SCTID:59150006" +- [type B pancreatic cell](http://purl.obolibrary.org/obo/CL_0000169) SubClassOf [enteroendocrine cell](http://purl.obolibrary.org/obo/CL_0000164) + - [is_inferred](http://www.geneontology.org/formats/oboInOwl#is_inferred) "true" -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "longitudinal muscle layer of small intestine" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14936" -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [label](http://www.w3.org/2000/01/rdf-schema#label) "small intestine smooth muscle longitudinal layer" -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum longitudinale (tunica muscularis) (intestinum tenue)" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14936" +### type B synovial cell `http://purl.obolibrary.org/obo/CL_0002301` +#### Removed +- [type B synovial cell](http://purl.obolibrary.org/obo/CL_0002301) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "longitudinal muscle of small intestine" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14936" -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "longitudinal muscle coat of small intestine" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14936" -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0012402" +### type EC enteroendocrine cell `http://purl.obolibrary.org/obo/CL_0000577` +#### Removed +- [type EC enteroendocrine cell](http://purl.obolibrary.org/obo/CL_0000577) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:0002065" -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A longitudinal muscle layer of muscular coat that is part of a small intestine smooth muscle." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum longitudinale tunicae muscularis intestini tenuis" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14936" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) +### type I cell of adrenal cortex `http://purl.obolibrary.org/obo/CL_0002099` +#### Removed +- [type I cell of adrenal cortex](http://purl.obolibrary.org/obo/CL_0002099) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000423" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "long pitch helicoidal muscle layer of small intestine" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14936" -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +### type I pneumocyte `http://purl.obolibrary.org/obo/CL_0002062` +#### Removed +- [type I pneumocyte](http://purl.obolibrary.org/obo/CL_0002062) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "longitudinal layer of small intestine muscularis propria" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14936" -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14936" -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum helicoidale longi gradus tunicae muscularis intestini tenuis" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" +### ubiquitin-like protein transferase activity `http://purl.obolibrary.org/obo/GO_0019787` +#### Removed +- [ubiquitin-like protein transferase activity](http://purl.obolibrary.org/obo/GO_0019787) SubClassOf [catalytic activity, acting on a protein](http://purl.obolibrary.org/obo/GO_0140096) -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MA:0001561" +- [ubiquitin-like protein transferase activity](http://purl.obolibrary.org/obo/GO_0019787) SubClassOf [transferase activity](http://purl.obolibrary.org/obo/GO_0016740) -- Class: [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) +#### Added +- [ubiquitin-like protein transferase activity](http://purl.obolibrary.org/obo/GO_0019787) [IAO_0000233](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24697"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) EquivalentTo [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [small intestine smooth muscle](http://purl.obolibrary.org/obo/UBERON_0004239)) +- [ubiquitin-like protein transferase activity](http://purl.obolibrary.org/obo/GO_0019787) SubClassOf [aminoacyltransferase activity](http://purl.obolibrary.org/obo/GO_0016755) -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [muscle layer of small intestine](http://purl.obolibrary.org/obo/UBERON_0011201) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [small intestine smooth muscle](http://purl.obolibrary.org/obo/UBERON_0004239) +### univalent carboacyl group `http://purl.obolibrary.org/obo/CHEBI_27207` +#### Removed +- [univalent carboacyl group](http://purl.obolibrary.org/obo/CHEBI_27207) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) SubClassOf [longitudinal muscle layer of muscular coat](http://purl.obolibrary.org/obo/UBERON_0012369) +- [univalent carboacyl group](http://purl.obolibrary.org/obo/CHEBI_27207) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "univalent carboxylic acyl groups" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" +- [univalent carboacyl group](http://purl.obolibrary.org/obo/CHEBI_27207) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "univalent acyl group" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -### smooth muscle cell of large intestine smooth muscle circular layer `http://purl.obolibrary.org/obo/CL_4033011` +- [univalent carboacyl group](http://purl.obolibrary.org/obo/CHEBI_27207) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "univalent carboacyl groups" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -#### Added -- [smooth muscle cell of large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/CL_4033011) [label](http://www.w3.org/2000/01/rdf-schema#label) "smooth muscle cell of large intestine smooth muscle circular layer"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [univalent carboacyl group](http://purl.obolibrary.org/obo/CHEBI_27207) [label](http://www.w3.org/2000/01/rdf-schema#label) "univalent carboacyl group" -- [smooth muscle cell of large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/CL_4033011) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) +- [univalent carboacyl group](http://purl.obolibrary.org/obo/CHEBI_27207) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:27207" -- [smooth muscle cell of large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/CL_4033011) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A(n) smooth muscle cell that is part of a(n) large intestine smooth muscle circular layer."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24997029"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [univalent carboacyl group](http://purl.obolibrary.org/obo/CHEBI_27207) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid." -- Class: [smooth muscle cell of large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/CL_4033011) +- [univalent carboacyl group](http://purl.obolibrary.org/obo/CHEBI_27207) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [smooth muscle cell of large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/CL_4033011) EquivalentTo [smooth muscle cell](http://purl.obolibrary.org/obo/CL_0000192) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012398)) +- Class: [univalent carboacyl group](http://purl.obolibrary.org/obo/CHEBI_27207) -- [smooth muscle cell of large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/CL_4033011) SubClassOf [smooth muscle cell of large intestine](http://purl.obolibrary.org/obo/CL_1000279) +- [univalent carboacyl group](http://purl.obolibrary.org/obo/CHEBI_27207) SubClassOf [carboacyl group](http://purl.obolibrary.org/obo/CHEBI_37838) -- [smooth muscle cell of large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/CL_4033011) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [large intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012398) -### smooth muscle cell of large intestine smooth muscle longitudinal layer `http://purl.obolibrary.org/obo/CL_4033012` +### unswitched memory B cell `http://purl.obolibrary.org/obo/CL_0000970` +#### Removed +- [unswitched memory B cell](http://purl.obolibrary.org/obo/CL_0000970) EquivalentTo [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgG immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071735)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgE immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071742)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgA immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071745)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [syndecan-1](http://purl.obolibrary.org/obo/PR_000001935)) -#### Added -- [smooth muscle cell of large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/CL_4033012) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) +- [unswitched memory B cell](http://purl.obolibrary.org/obo/CL_0000970) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgG immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071735) -- [smooth muscle cell of large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/CL_4033012) [label](http://www.w3.org/2000/01/rdf-schema#label) "smooth muscle cell of large intestine smooth muscle longitudinal layer"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [unswitched memory B cell](http://purl.obolibrary.org/obo/CL_0000970) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgA immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071745) -- [smooth muscle cell of large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/CL_4033012) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A(n) smooth muscle cell that is part of a(n) large intestine smooth muscle longitudinal layer."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:24997029"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [unswitched memory B cell](http://purl.obolibrary.org/obo/CL_0000970) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [IgE immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071742) -- Class: [smooth muscle cell of large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/CL_4033012) +#### Added +- [unswitched memory B cell](http://purl.obolibrary.org/obo/CL_0000970) EquivalentTo [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgG immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071735)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgE immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071742)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgA immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071745)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [syndecan-1](http://purl.obolibrary.org/obo/PR_000001935)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgD immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071738)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [IgM immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071753)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD27 molecule](http://purl.obolibrary.org/obo/PR_000001963)) -- [smooth muscle cell of large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/CL_4033012) EquivalentTo [smooth muscle cell](http://purl.obolibrary.org/obo/CL_0000192) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012399)) +- [unswitched memory B cell](http://purl.obolibrary.org/obo/CL_0000970) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgE immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071742) -- [smooth muscle cell of large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/CL_4033012) SubClassOf [smooth muscle cell of large intestine](http://purl.obolibrary.org/obo/CL_1000279) +- [unswitched memory B cell](http://purl.obolibrary.org/obo/CL_0000970) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgA immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071745) -- [smooth muscle cell of large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/CL_4033012) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [large intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012399) +- [unswitched memory B cell](http://purl.obolibrary.org/obo/CL_0000970) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [IgG immunoglobulin complex](http://purl.obolibrary.org/obo/GO_0071735) -### smooth muscle cell of taenia coli `http://purl.obolibrary.org/obo/CL_4033004` +### ureteral cell `http://purl.obolibrary.org/obo/CL_1000601` +#### Removed +- [ureteral cell](http://purl.obolibrary.org/obo/CL_1000601) SubClassOf [independent continuant](http://purl.obolibrary.org/obo/BFO_0000004) -#### Added -- [smooth muscle cell of taenia coli](http://purl.obolibrary.org/obo/CL_4033004) [label](http://www.w3.org/2000/01/rdf-schema#label) "smooth muscle cell of taenia coli"^^[string](http://www.w3.org/2001/XMLSchema#string) -- [smooth muscle cell of taenia coli](http://purl.obolibrary.org/obo/CL_4033004) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) -- [smooth muscle cell of taenia coli](http://purl.obolibrary.org/obo/CL_4033004) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A(n) smooth muscle cell that is part of a(n) taenia coli."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22320805"^^[string](http://www.w3.org/2001/XMLSchema#string) +### uterus or analog `http://purl.obolibrary.org/obo/UBERON_0006834` +#### Removed +- [uterus or analog](http://purl.obolibrary.org/obo/UBERON_0006834) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004924" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10715339"^^[string](http://www.w3.org/2001/XMLSchema#string) -- Class: [smooth muscle cell of taenia coli](http://purl.obolibrary.org/obo/CL_4033004) -- [smooth muscle cell of taenia coli](http://purl.obolibrary.org/obo/CL_4033004) EquivalentTo [smooth muscle cell](http://purl.obolibrary.org/obo/CL_0000192) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419)) +### vacuolar calcium ion homeostasis `http://purl.obolibrary.org/obo/GO_0007036` -- [smooth muscle cell of taenia coli](http://purl.obolibrary.org/obo/CL_4033004) SubClassOf [smooth muscle cell of large intestine](http://purl.obolibrary.org/obo/CL_1000279) +#### Added +- [vacuolar calcium ion homeostasis](http://purl.obolibrary.org/obo/GO_0007036) SubClassOf [intracellular chemical homeostasis](http://purl.obolibrary.org/obo/GO_0055082) -- [smooth muscle cell of taenia coli](http://purl.obolibrary.org/obo/CL_4033004) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) +- [vacuolar calcium ion homeostasis](http://purl.obolibrary.org/obo/GO_0007036) SubClassOf [calcium ion homeostasis](http://purl.obolibrary.org/obo/GO_0055074) -### smooth muscle tissue of bronchiole `http://purl.obolibrary.org/obo/UBERON_0004515` +### vasoconstrictor agent `http://purl.obolibrary.org/obo/CHEBI_50514` #### Removed -- [smooth muscle tissue of bronchiole](http://purl.obolibrary.org/obo/UBERON_0004515) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:261081" +- [vasoconstrictor agent](http://purl.obolibrary.org/obo/CHEBI_50514) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Drug used to cause constriction of the blood vessels." -- [smooth muscle tissue of bronchiole](http://purl.obolibrary.org/obo/UBERON_0004515) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "smooth muscle tissue of lobular bronchiole" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:261081" +- [vasoconstrictor agent](http://purl.obolibrary.org/obo/CHEBI_50514) [label](http://www.w3.org/2000/01/rdf-schema#label) "vasoconstrictor agent" -- [smooth muscle tissue of bronchiole](http://purl.obolibrary.org/obo/UBERON_0004515) SubClassOf [bronchus smooth muscle](http://purl.obolibrary.org/obo/UBERON_0004242) +- [vasoconstrictor agent](http://purl.obolibrary.org/obo/CHEBI_50514) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:50514" -#### Added -- [smooth muscle tissue of bronchiole](http://purl.obolibrary.org/obo/UBERON_0004515) SubClassOf [lower respiratory tract smooth muscle](http://purl.obolibrary.org/obo/UBERON_0004233) +- [vasoconstrictor agent](http://purl.obolibrary.org/obo/CHEBI_50514) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" +- [vasoconstrictor agent](http://purl.obolibrary.org/obo/CHEBI_50514) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -### smooth muscle tissue of lobular bronchiole `http://purl.obolibrary.org/obo/UBERON_8600003` +- Class: [vasoconstrictor agent](http://purl.obolibrary.org/obo/CHEBI_50514) -#### Added -- [smooth muscle tissue of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600003) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:8600003" +- [vasoconstrictor agent](http://purl.obolibrary.org/obo/CHEBI_50514) SubClassOf [cardiovascular drug](http://purl.obolibrary.org/obo/CHEBI_35554) -- [smooth muscle tissue of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600003) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](http://orcid.org/0000-0001-6677-8489) -- [smooth muscle tissue of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600003) [label](http://www.w3.org/2000/01/rdf-schema#label) "smooth muscle tissue of lobular bronchiole" -- [smooth muscle tissue of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600003) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A smooth muscle tissue that is part of a lobular bronchiole." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:261081" +### vasodilator agent `http://purl.obolibrary.org/obo/CHEBI_35620` +#### Removed +- [vasodilator agent](http://purl.obolibrary.org/obo/CHEBI_35620) [label](http://www.w3.org/2000/01/rdf-schema#label) "vasodilator agent" -- [smooth muscle tissue of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600003) [date](http://purl.org/dc/terms/date) "2023-02-10T14:54:06Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) +- [vasodilator agent](http://purl.obolibrary.org/obo/CHEBI_35620) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vasodilator" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [smooth muscle tissue of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600003) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [vasodilator agent](http://purl.obolibrary.org/obo/CHEBI_35620) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A drug used to cause dilation of the blood vessels." -- Class: [smooth muscle tissue of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600003) +- [vasodilator agent](http://purl.obolibrary.org/obo/CHEBI_35620) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [smooth muscle tissue of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600003) EquivalentTo [smooth muscle tissue](http://purl.obolibrary.org/obo/UBERON_0001135) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600000)) +- [vasodilator agent](http://purl.obolibrary.org/obo/CHEBI_35620) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:35620" -- [smooth muscle tissue of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600003) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600000) +- [vasodilator agent](http://purl.obolibrary.org/obo/CHEBI_35620) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [smooth muscle tissue of lobular bronchiole](http://purl.obolibrary.org/obo/UBERON_8600003) SubClassOf [smooth muscle tissue of bronchiole](http://purl.obolibrary.org/obo/UBERON_0004515) +- [vasodilator agent](http://purl.obolibrary.org/obo/CHEBI_35620) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vasodilator agents" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" +- Class: [vasodilator agent](http://purl.obolibrary.org/obo/CHEBI_35620) -### splanchnocranium `http://purl.obolibrary.org/obo/UBERON_0008895` -#### Removed -- [splanchnocranium](http://purl.obolibrary.org/obo/UBERON_0008895) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [vasodilator agent](http://purl.obolibrary.org/obo/CHEBI_35620) SubClassOf [cardiovascular drug](http://purl.obolibrary.org/obo/CHEBI_35554) -### strand of hair `http://purl.obolibrary.org/obo/UBERON_0001037` +### vasopressin `http://purl.obolibrary.org/obo/CHEBI_9937` #### Removed -- [strand of hair](http://purl.obolibrary.org/obo/UBERON_0001037) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Antidiuretic hormone" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -### stromal cell of endometrium `http://purl.obolibrary.org/obo/CL_0002255` -#### Removed -- [stromal cell of endometrium](http://purl.obolibrary.org/obo/CL_0002255) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Connective tissue cells of the endometrium, these cells are fibroblastic in appearance. During decidualization they tranform into decidual (stromal) cells, swellling up and adopt an epithelial cell-like appearance due to the accumulation of glycogen and lipid droplets."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11331626"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "argipressin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" + +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A family of cyclic nonapeptide hormones found in most mammals. Synthesised in the hypothalamus and stored in the post-pituitary, vasopressins play a key role in homeostasis, particularly in regulating the body's water content. Together with the similar neuropeptide oxytocin, they are believed to influence social cognition and behaviour." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30013421"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:9937" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wiki:Decidualization&oldid=908981933#Endometrial_stromal_cells_(ESCs)"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arginine vasopressin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [stromal cell of endometrium](http://purl.obolibrary.org/obo/CL_0002255) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [endometrium](http://purl.obolibrary.org/obo/UBERON_0001295) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -#### Added -- [stromal cell of endometrium](http://purl.obolibrary.org/obo/CL_0002255) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A stromal cell of the endometrium that is fibroblastic in appearance. During decidualization this cell may differentiate into a decidual stromal cell."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://doi.org/10.1038/s41591-020-1040-z"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20445498" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11331626"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D00101" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30309298"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [label](http://www.w3.org/2000/01/rdf-schema#label) "vasopressin" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30013421"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "AVP" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wiki:Decidualization&oldid=908981933#Endometrial_stromal_cells_(ESCs)"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ADH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" -- [stromal cell of endometrium](http://purl.obolibrary.org/obo/CL_0002255) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "endometrial stromal fibroblast"^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30309298"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [formula](http://purl.obolibrary.org/obo/chebi/formula) "C46H65N15O12S2.C46H65N13O12S2" -- [stromal cell of endometrium](http://purl.obolibrary.org/obo/CL_0002255) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [endometrial stroma](http://purl.obolibrary.org/obo/UBERON_0002337) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Inyectable de vasopresina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" -- [stromal cell of endometrium](http://purl.obolibrary.org/obo/CL_0002255) SubClassOf [has potential to directly develop into](http://purl.obolibrary.org/obo/RO_0002388) some [decidual cell](http://purl.obolibrary.org/obo/CL_2000002) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00840" -### submucosa of bronchiole `http://purl.obolibrary.org/obo/UBERON_0004952` -#### Removed -- [submucosa of bronchiole](http://purl.obolibrary.org/obo/UBERON_0004952) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "submucosa of lobular bronchiole" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "beta-Hypophamine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" -- [submucosa of bronchiole](http://purl.obolibrary.org/obo/UBERON_0004952) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobular bronchiole submucosa" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Vasopressin" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" -- [submucosa of bronchiole](http://purl.obolibrary.org/obo/UBERON_0004952) SubClassOf [submucosa of bronchus](http://purl.obolibrary.org/obo/UBERON_0001957) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Vasopressini injectio" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" -#### Added -- [submucosa of bronchiole](http://purl.obolibrary.org/obo/UBERON_0004952) SubClassOf [respiratory system submucosa](http://purl.obolibrary.org/obo/UBERON_0004777) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "2138.86956" -### suprabasal keratinocyte `http://purl.obolibrary.org/obo/CL_4033013` +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "VP" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" -#### Added -- [suprabasal keratinocyte](http://purl.obolibrary.org/obo/CL_4033013) [creation_date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2023-02-02T11:17:04Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Solute injectable de vasopressine" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChemIDplus" -- [suprabasal keratinocyte](http://purl.obolibrary.org/obo/CL_4033013) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A keratinocyte of the epidermis suprabasal layer. This cell may express the differentiation markers keratin 10 and keratin 1." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://www.proteinatlas.org/humanproteome/single+cell+type/squamous+epithelial+cells#suprabasalkeratinocytes"^^[string](http://www.w3.org/2001/XMLSchema#string) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [INN](http://purl.obolibrary.org/obo/chebi#INN) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:35883599"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18988842" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Europe PMC" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9520465"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:11000-17-2" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" -- [suprabasal keratinocyte](http://purl.obolibrary.org/obo/CL_4033013) [label](http://www.w3.org/2000/01/rdf-schema#label) "suprabasal keratinocyte" +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) [mass](http://purl.obolibrary.org/obo/chebi/mass) "2140.458" -- [suprabasal keratinocyte](http://purl.obolibrary.org/obo/CL_4033013) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](http://orcid.org/0000-0001-6677-8489) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) SubClassOf [peptide hormone](http://purl.obolibrary.org/obo/CHEBI_25905) -- Class: [suprabasal keratinocyte](http://purl.obolibrary.org/obo/CL_4033013) +- [vasopressin](http://purl.obolibrary.org/obo/CHEBI_9937) SubClassOf [heterodetic cyclic peptide](http://purl.obolibrary.org/obo/CHEBI_24533) -- [suprabasal keratinocyte](http://purl.obolibrary.org/obo/CL_4033013) EquivalentTo [keratinocyte](http://purl.obolibrary.org/obo/CL_0000312) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epidermis suprabasal layer](http://purl.obolibrary.org/obo/UBERON_0010402)) -- [suprabasal keratinocyte](http://purl.obolibrary.org/obo/CL_4033013) SubClassOf [keratinocyte](http://purl.obolibrary.org/obo/CL_0000312) -- [suprabasal keratinocyte](http://purl.obolibrary.org/obo/CL_4033013) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [epidermis suprabasal layer](http://purl.obolibrary.org/obo/UBERON_0010402) +### vein endothelial cell `http://purl.obolibrary.org/obo/CL_0002543` +#### Removed +- [vein endothelial cell](http://purl.obolibrary.org/obo/CL_0002543) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CL:1000393" -### taenia coli `http://purl.obolibrary.org/obo/UBERON_0012419` -#### Added -- [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) +### visceral muscle cell `http://purl.obolibrary.org/obo/CL_0008007` +#### Removed +- [visceral muscle cell](http://purl.obolibrary.org/obo/CL_0008007) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A muscle cell that is part of some visceral muscle" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dos" -- [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +#### Added +- [visceral muscle cell](http://purl.obolibrary.org/obo/CL_0008007) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A muscle cell that is part of some visceral muscle." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dos" -- [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tenia coli" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Taenia_coli" +- [visceral muscle cell](http://purl.obolibrary.org/obo/CL_0008007) EquivalentTo [muscle cell](http://purl.obolibrary.org/obo/CL_0000187) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [visceral muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600004)) -- [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "teniae coli" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Taenia_coli" +- [visceral muscle cell](http://purl.obolibrary.org/obo/CL_0008007) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [visceral muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600004) -- [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) [label](http://www.w3.org/2000/01/rdf-schema#label) "taenia coli" -- [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "longitudinal band of large intestine muscularis" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15041" +### visceral muscle tissue `http://purl.obolibrary.org/obo/UBERON_8600004` -- [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "longitudinal bands" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Taenia_coli" +#### Added +- [visceral muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600004) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "visceral muscle" + - [comment](http://www.w3.org/2000/01/rdf-schema#comment) "BTO:0002780" -- [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "taeniae coli" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Taenia_coli" +- [visceral muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600004) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A muscle tissue that is associated with soft internal organs (viscera)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002780" -- [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Taenia_coli" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CLAO:0001295" -- [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0012419" +- [visceral muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600004) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "It is quite common to refer to visceral muscles as smooth muscles, by analogy with vertebrates; however, most visceral muscles in arthropods are actually striated." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://en.wikipedia.org/wiki/Smooth_muscle" -- [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The taeniae coli (also teniae coli) are three separate longitudinal ribbons of smooth muscle on the outside of the ascending, transverse, descending and sigmoid colons. They are visible, and can be seen just below the serosa or fibrosa. They are the Mesocolic, Free and Omental Coli. The teniae coli contracts length wise to produce the haustra, the bulges in the colon. The bands converge at the root of the vermiform appendix and the rectum. These bands correspond to the outer layer of the muscularis externa, in other portions of the digestive tract." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Taenia_coli" + - [comment](http://www.w3.org/2000/01/rdf-schema#comment) "PMID:8720463" -- [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15041" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005070" -- [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "SCTID:362160001" +- [visceral muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600004) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" -- [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) +- [visceral muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600004) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:8600004" -- Class: [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) +- [visceral muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600004) [label](http://www.w3.org/2000/01/rdf-schema#label) "visceral muscle tissue" -- [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) SubClassOf [layer of smooth muscle tissue](http://purl.obolibrary.org/obo/UBERON_0034933) +- [visceral muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600004) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) -- [taenia coli](http://purl.obolibrary.org/obo/UBERON_0012419) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [muscle layer of large intestine](http://purl.obolibrary.org/obo/UBERON_0011198) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" +- [visceral muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600004) [date](http://purl.org/dc/terms/date) "2023-02-16T10:17:46Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) +- Class: [visceral muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600004) -### telencephalon `http://purl.obolibrary.org/obo/UBERON_0001893` -#### Removed -- [telencephalon](http://purl.obolibrary.org/obo/UBERON_0001893) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [visceral muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600004) SubClassOf [muscle tissue](http://purl.obolibrary.org/obo/UBERON_0002385) +- [visceral muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600004) SubClassOf [composed primarily of](http://purl.obolibrary.org/obo/RO_0002473) some [visceral muscle cell](http://purl.obolibrary.org/obo/CL_0008007) -### thecogen cell `http://purl.obolibrary.org/obo/CL_0000380` +### visceral striated muscle tissue `http://purl.obolibrary.org/obo/UBERON_8600006` #### Added -- [thecogen cell](http://purl.obolibrary.org/obo/CL_0000380) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005173"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [visceral striated muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600006) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [visceral striated muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600006) [label](http://www.w3.org/2000/01/rdf-schema#label) "visceral striated muscle tissue" -### thyroid-stimulating hormone-secreting cell development `http://purl.obolibrary.org/obo/GO_0060130` +- [visceral striated muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600006) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) -#### Added -- [thyroid-stimulating hormone-secreting cell development](http://purl.obolibrary.org/obo/GO_0060130) SubClassOf [neuron development](http://purl.obolibrary.org/obo/GO_0048666) +- [visceral striated muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600006) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:8600006" +- [visceral striated muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600006) [date](http://purl.org/dc/terms/date) "2023-02-16T10:34:43Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) -### tissue `http://purl.obolibrary.org/obo/UBERON_0000479` +- [visceral striated muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600006) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A striated muscle tissue that is associated with soft internal organs (viscera)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://pressbooks.pub/rbtallitsch/chapter/chapter-6-muscle-tissue/" -#### Added -- [tissue](http://purl.obolibrary.org/obo/UBERON_0000479) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [common_anatomy](http://purl.obolibrary.org/obo/uberon/core#common_anatomy) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:8720463" -- [tissue](http://purl.obolibrary.org/obo/UBERON_0000479) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) +- [visceral striated muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600006) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "striated visceral muscle tissue" -- [tissue](http://purl.obolibrary.org/obo/UBERON_0000479) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Fungi](http://purl.obolibrary.org/obo/NCBITaxon_4751) +- Class: [visceral striated muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600006) -- [tissue](http://purl.obolibrary.org/obo/UBERON_0000479) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) +- [visceral striated muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600006) SubClassOf [visceral muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600004) +- [visceral striated muscle tissue](http://purl.obolibrary.org/obo/UBERON_8600006) SubClassOf [striated muscle tissue](http://purl.obolibrary.org/obo/UBERON_0002036) -### tongue `http://purl.obolibrary.org/obo/UBERON_0001723` + +### visual pigment cell (sensu Vertebrata) `http://purl.obolibrary.org/obo/CL_0000343` #### Removed -- [tongue](http://purl.obolibrary.org/obo/UBERON_0001723) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [visual pigment cell (sensu Vertebrata)](http://purl.obolibrary.org/obo/CL_0000343) SubClassOf [material entity](http://purl.obolibrary.org/obo/BFO_0000040) -### trachea cartilage `http://purl.obolibrary.org/obo/UBERON_0003604` +### voltage-gated calcium channel activity `http://purl.obolibrary.org/obo/GO_0005245` #### Removed -- [trachea cartilage](http://purl.obolibrary.org/obo/UBERON_0003604) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [voltage-gated calcium channel activity](http://purl.obolibrary.org/obo/GO_0005245) SubClassOf [voltage-gated monoatomic cation channel activity](http://purl.obolibrary.org/obo/GO_0022843) +#### Added +- [voltage-gated calcium channel activity](http://purl.obolibrary.org/obo/GO_0005245) SubClassOf [voltage-gated channel activity](http://purl.obolibrary.org/obo/GO_0022832) -### trachea connective tissue `http://purl.obolibrary.org/obo/UBERON_0003571` +### voltage-gated monoatomic cation channel activity `http://purl.obolibrary.org/obo/GO_0022843` #### Removed -- [trachea connective tissue](http://purl.obolibrary.org/obo/UBERON_0003571) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [voltage-gated monoatomic cation channel activity](http://purl.obolibrary.org/obo/GO_0022843) SubClassOf [voltage-gated monoatomic ion channel activity](http://purl.obolibrary.org/obo/GO_0005244) #### Added -- [trachea connective tissue](http://purl.obolibrary.org/obo/UBERON_0003571) SubClassOf [anatomical entity](http://purl.obolibrary.org/obo/CARO_0000000) +- [voltage-gated monoatomic cation channel activity](http://purl.obolibrary.org/obo/GO_0022843) SubClassOf [voltage-gated channel activity](http://purl.obolibrary.org/obo/GO_0022832) -### transitively_connected to `http://purl.obolibrary.org/obo/uberon/core#transitively_connected_to` +### water `http://purl.obolibrary.org/obo/CHEBI_15377` #### Removed -- [transitively_connected to](http://purl.obolibrary.org/obo/uberon/core#transitively_connected_to) [label](http://www.w3.org/2000/01/rdf-schema#label) "transitively_connected to" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "oxidane" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [transitively_connected to](http://purl.obolibrary.org/obo/uberon/core#transitively_connected_to) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [transitively_connected to](http://purl.obolibrary.org/obo/uberon/core#transitively_connected_to) [id](http://www.geneontology.org/formats/oboInOwl#id) "transitively_connected_to" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:27313" -- ObjectProperty: [transitively_connected to](http://purl.obolibrary.org/obo/uberon/core#transitively_connected_to) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [charge](http://purl.obolibrary.org/obo/chebi/charge) "0" -- Transitive: [transitively_connected to](http://purl.obolibrary.org/obo/uberon/core#transitively_connected_to) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [monoisotopicmass](http://purl.obolibrary.org/obo/chebi/monoisotopicmass) "18.01056" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [inchikey](http://purl.obolibrary.org/obo/chebi/inchikey) "XLYOFNOQVPJJNP-UHFFFAOYSA-N" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "H2O" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProt" -### trigeminal nerve muscle `http://purl.obolibrary.org/obo/UBERON_0018544` -#### Removed -- [trigeminal nerve muscle](http://purl.obolibrary.org/obo/UBERON_0018544) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HMDB:HMDB0002111" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Water" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Beilstein:3587155" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Beilstein" -### truncus arteriosus `http://purl.obolibrary.org/obo/UBERON_0002061` -#### Removed -- [truncus arteriosus](http://purl.obolibrary.org/obo/UBERON_0002061) SubClassOf [structure with developmental contribution from neural crest](http://purl.obolibrary.org/obo/UBERON_0010314) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dihydrogen oxide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7732-18-5" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIST Chemistry WebBook" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Water" -### tyrosine-protein kinase receptor UFO `http://purl.obolibrary.org/obo/PR_000004528` +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:43228" -#### Added -- [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) [label](http://www.w3.org/2000/01/rdf-schema#label) "tyrosine-protein kinase receptor UFO" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "eau" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "adhesion-related kinase" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "[OH2]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A protein that is a translation product of the human AXL gene or a 1:1 ortholog thereof." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:DNx" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:44819" -- [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) [id](http://www.geneontology.org/formats/oboInOwl#id) "PR:000004528" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:10743" -- [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "AXL oncogene" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms" -- [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "UFO" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [Gene-based](http://purl.obolibrary.org/obo/pr#Gene-based) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [formula](http://purl.obolibrary.org/obo/chebi/formula) "H2O" -- [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Category=gene." +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:42043" -- [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "protein" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "BOUND WATER" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" + +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aqua" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ark" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [Gene-based](http://purl.obolibrary.org/obo/pr#Gene-based) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7732-18-5" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ChemIDplus" -- [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "AXL" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [PRO-short-label](http://purl.obolibrary.org/obo/pr#PRO-short-label) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [mass](http://purl.obolibrary.org/obo/chebi/mass) "18.01530" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:DNx" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPHARobj:1835" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "HOH" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- Class: [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reaxys:3587155" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Reaxys" -- [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) SubClassOf [protein](http://purl.obolibrary.org/obo/PR_000000001) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "agua" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) SubClassOf [protein](http://purl.obolibrary.org/obo/CHEBI_36080) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem:HOH" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "H2O" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG_COMPOUND" -### tyrosine-protein kinase receptor UFO (human) `http://purl.obolibrary.org/obo/PR_P30530` +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:44292" -#### Added -- [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "AXL" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:P30530" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:44701" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [Gene-based](http://purl.obolibrary.org/obo/pr#Gene-based) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dihydridooxygen" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "UFO" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:P30530" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:C00001" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [Gene-based](http://purl.obolibrary.org/obo/pr#Gene-based) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:15377" -- [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Category=organism-gene." +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MetaCyc:WATER" -- [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:P30530" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [label](http://www.w3.org/2000/01/rdf-schema#label) "water" -- [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) [label](http://www.w3.org/2000/01/rdf-schema#label) "tyrosine-protein kinase receptor UFO (human)" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "CAS:7732-18-5" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "KEGG COMPOUND" -- [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "AXL oncogene (human)" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:P30530" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acqua" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "protein" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "WATER" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PDBeChem" -- [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hAXL" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [PRO-short-label](http://purl.obolibrary.org/obo/pr#PRO-short-label) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "KEGG:D00001" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:DNx" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:5585" -- [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A tyrosine-protein kinase receptor UFO that is encoded in the genome of human." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:DNx" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [inchi](http://purl.obolibrary.org/obo/chebi/inchi) "InChI=1S/H2O/h1H2" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:P30530" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:13352" -- [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) [id](http://www.geneontology.org/formats/oboInOwl#id) "PR:P30530" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MolBase:1" -- [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DTO:03100553" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- Class: [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Gmelin:117" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Gmelin" -- [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) EquivalentTo [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) and ([only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606)) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hydrogen hydroxide" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) SubClassOf [Homo sapiens protein](http://purl.obolibrary.org/obo/PR_000029067) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "CHEBI:42857" -- [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) SubClassOf [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "water" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -### tyrosine-protein kinase receptor UFO (mouse) `http://purl.obolibrary.org/obo/PR_Q00993` +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [smiles](http://purl.obolibrary.org/obo/chebi/smiles) "[H]O[H]" -#### Added -- [tyrosine-protein kinase receptor UFO (mouse)](http://purl.obolibrary.org/obo/PR_Q00993) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Axl" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:Q00993" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Wasser" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [Gene-based](http://purl.obolibrary.org/obo/pr#Gene-based) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Escherichia coli metabolite](http://purl.obolibrary.org/obo/CHEBI_76971) -- [tyrosine-protein kinase receptor UFO (mouse)](http://purl.obolibrary.org/obo/PR_Q00993) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ufo" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:Q00993" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) SubClassOf [is_conjugate_base_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of) some [oxonium](http://purl.obolibrary.org/obo/CHEBI_29412) - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [Gene-based](http://purl.obolibrary.org/obo/pr#Gene-based) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [greenhouse gas](http://purl.obolibrary.org/obo/CHEBI_76413) -- [tyrosine-protein kinase receptor UFO (mouse)](http://purl.obolibrary.org/obo/PR_Q00993) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Ark" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:Q00993" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) SubClassOf [mononuclear parent hydride](http://purl.obolibrary.org/obo/CHEBI_37176) - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [Gene-based](http://purl.obolibrary.org/obo/pr#Gene-based) +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) SubClassOf [inorganic hydroxy compound](http://purl.obolibrary.org/obo/CHEBI_52625) -- [tyrosine-protein kinase receptor UFO (mouse)](http://purl.obolibrary.org/obo/PR_Q00993) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "protein" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [Saccharomyces cerevisiae metabolite](http://purl.obolibrary.org/obo/CHEBI_75772) -- [tyrosine-protein kinase receptor UFO (mouse)](http://purl.obolibrary.org/obo/PR_Q00993) [label](http://www.w3.org/2000/01/rdf-schema#label) "tyrosine-protein kinase receptor UFO (mouse)" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) SubClassOf [is_conjugate_acid_of](http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of) some [hydroxide](http://purl.obolibrary.org/obo/CHEBI_16234) -- [tyrosine-protein kinase receptor UFO (mouse)](http://purl.obolibrary.org/obo/PR_Q00993) [id](http://www.geneontology.org/formats/oboInOwl#id) "PR:Q00993" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [amphiprotic solvent](http://purl.obolibrary.org/obo/CHEBI_48360) -- [tyrosine-protein kinase receptor UFO (mouse)](http://purl.obolibrary.org/obo/PR_Q00993) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "adhesion-related kinase (mouse)" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:Q00993" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [human metabolite](http://purl.obolibrary.org/obo/CHEBI_77746) -- [tyrosine-protein kinase receptor UFO (mouse)](http://purl.obolibrary.org/obo/PR_Q00993) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UniProtKB:Q00993" +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) SubClassOf [has role](http://purl.obolibrary.org/obo/RO_0000087) some [mouse metabolite](http://purl.obolibrary.org/obo/CHEBI_75771) -- [tyrosine-protein kinase receptor UFO (mouse)](http://purl.obolibrary.org/obo/PR_Q00993) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Category=organism-gene." +- [water](http://purl.obolibrary.org/obo/CHEBI_15377) SubClassOf [oxygen hydride](http://purl.obolibrary.org/obo/CHEBI_33693) -- [tyrosine-protein kinase receptor UFO (mouse)](http://purl.obolibrary.org/obo/PR_Q00993) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A tyrosine-protein kinase receptor UFO that is encoded in the genome of mouse." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OMA:Q00993" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:DNx" -- [tyrosine-protein kinase receptor UFO (mouse)](http://purl.obolibrary.org/obo/PR_Q00993) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "mAXL" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [PRO-short-label](http://purl.obolibrary.org/obo/pr#PRO-short-label) +### water homeostasis `http://purl.obolibrary.org/obo/GO_0030104` +#### Removed +- [water homeostasis](http://purl.obolibrary.org/obo/GO_0030104) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process involved in the maintenance of an internal steady state of water within an organism or cell." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dph" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:DNx" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" -- Class: [tyrosine-protein kinase receptor UFO (mouse)](http://purl.obolibrary.org/obo/PR_Q00993) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" -- [tyrosine-protein kinase receptor UFO (mouse)](http://purl.obolibrary.org/obo/PR_Q00993) EquivalentTo [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) and ([only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090)) +- [water homeostasis](http://purl.obolibrary.org/obo/GO_0030104) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Osmoregulation" -- [tyrosine-protein kinase receptor UFO (mouse)](http://purl.obolibrary.org/obo/PR_Q00993) SubClassOf [tyrosine-protein kinase receptor UFO](http://purl.obolibrary.org/obo/PR_000004528) +- [water homeostasis](http://purl.obolibrary.org/obo/GO_0030104) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of osmotic pressure" -- [tyrosine-protein kinase receptor UFO (mouse)](http://purl.obolibrary.org/obo/PR_Q00993) SubClassOf [Mus musculus protein](http://purl.obolibrary.org/obo/PR_000029032) +- [water homeostasis](http://purl.obolibrary.org/obo/GO_0030104) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" +- [water homeostasis](http://purl.obolibrary.org/obo/GO_0030104) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "GO:0018987" -### tyrosine-protein kinase receptor UFO, signal peptide removed form (human) `http://purl.obolibrary.org/obo/PR_000046449` +- [water homeostasis](http://purl.obolibrary.org/obo/GO_0030104) [label](http://www.w3.org/2000/01/rdf-schema#label) "water homeostasis" -#### Added -- [tyrosine-protein kinase receptor UFO, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000046449) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "PRO_0000024481" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:DNx" +- [water homeostasis](http://purl.obolibrary.org/obo/GO_0030104) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0030104" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [PRO-proteoform-ftid](http://purl.obolibrary.org/obo/pr#PRO-proteoform-ftid) +- [water homeostasis](http://purl.obolibrary.org/obo/GO_0030104) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "osmoregulation" -- [tyrosine-protein kinase receptor UFO, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000046449) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Category=organism-modification." +- Class: [water homeostasis](http://purl.obolibrary.org/obo/GO_0030104) -- [tyrosine-protein kinase receptor UFO, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000046449) [label](http://www.w3.org/2000/01/rdf-schema#label) "tyrosine-protein kinase receptor UFO, signal peptide removed form (human)" +- [water homeostasis](http://purl.obolibrary.org/obo/GO_0030104) EquivalentTo [chemical homeostasis](http://purl.obolibrary.org/obo/GO_0048878) and ([regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [water](http://purl.obolibrary.org/obo/CHEBI_15377)) -- [tyrosine-protein kinase receptor UFO, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000046449) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-197705" - - [label](http://www.w3.org/2000/01/rdf-schema#label) "PR:000046449 located_in GO:0005886" +- [water homeostasis](http://purl.obolibrary.org/obo/GO_0030104) SubClassOf [chemical homeostasis](http://purl.obolibrary.org/obo/GO_0048878) -- [tyrosine-protein kinase receptor UFO, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000046449) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hAXL/SigPep-" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [PRO-short-label](http://purl.obolibrary.org/obo/pr#PRO-short-label) +- [water homeostasis](http://purl.obolibrary.org/obo/GO_0030104) SubClassOf [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [water](http://purl.obolibrary.org/obo/CHEBI_15377) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:DNx" -- [tyrosine-protein kinase receptor UFO, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000046449) [id](http://www.geneontology.org/formats/oboInOwl#id) "PR:000046449" -- [tyrosine-protein kinase receptor UFO, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000046449) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "UniProtKB:P30530, 26-894" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:DNx" +### water transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0005372` +#### Removed +- [water transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005372) SubClassOf [inorganic molecular entity transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015318) - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [PRO-proteoform-std](http://purl.obolibrary.org/obo/pr#PRO-proteoform-std) +#### Added +- [water transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0005372) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) -- [tyrosine-protein kinase receptor UFO, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000046449) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A tyrosine-protein kinase receptor UFO (human) that has had the signal peptide removed. UniProtKB:P30530, 26-894." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PRO:DNx" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Reactome:R-HSA-197705" +### xenobiotic metabolite `http://purl.obolibrary.org/obo/CHEBI_76206` +#### Removed +- [xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76206) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [tyrosine-protein kinase receptor UFO, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000046449) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "protein" +- [xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76206) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -- Class: [tyrosine-protein kinase receptor UFO, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000046449) +- [xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76206) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any metabolite produced by metabolism of a xenobiotic compound." -- [tyrosine-protein kinase receptor UFO, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000046449) EquivalentTo [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) and ([lacks_part](http://purl.obolibrary.org/obo/pr#lacks_part) some [SO_0000418](http://purl.obolibrary.org/obo/SO_0000418)) +- [xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76206) [label](http://www.w3.org/2000/01/rdf-schema#label) "xenobiotic metabolite" -- [tyrosine-protein kinase receptor UFO, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000046449) SubClassOf [tyrosine-protein kinase receptor UFO (human)](http://purl.obolibrary.org/obo/PR_P30530) +- [xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76206) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "xenobiotic metabolites" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ChEBI" -- [tyrosine-protein kinase receptor UFO, signal peptide removed form (human)](http://purl.obolibrary.org/obo/PR_000046449) SubClassOf [lacks_part](http://purl.obolibrary.org/obo/pr#lacks_part) some [SO_0000418](http://purl.obolibrary.org/obo/SO_0000418) +- [xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76206) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:76206" +- Class: [xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76206) -### ureter luminal urothelium `http://purl.obolibrary.org/obo/UBERON_0011947` +- [xenobiotic metabolite](http://purl.obolibrary.org/obo/CHEBI_76206) SubClassOf [metabolite](http://purl.obolibrary.org/obo/CHEBI_25212) -#### Added -- [ureter luminal urothelium](http://purl.obolibrary.org/obo/UBERON_0011947) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A luminal layer of epithelium that is part of a ureter." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" -- [ureter luminal urothelium](http://purl.obolibrary.org/obo/UBERON_0011947) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0011947" -- [ureter luminal urothelium](http://purl.obolibrary.org/obo/UBERON_0011947) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MA:0002656" +### yolk sac hematopoietic stem cell `http://purl.obolibrary.org/obo/CL_0002354` +#### Removed +- [yolk sac hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002354) EquivalentTo [gestational hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002352) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC protein complex](http://purl.obolibrary.org/obo/GO_0042611)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C](http://purl.obolibrary.org/obo/PR_000001006)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) -- [ureter luminal urothelium](http://purl.obolibrary.org/obo/UBERON_0011947) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EMAPA:37779" - - [source](http://www.geneontology.org/formats/oboInOwl#source) "MA:th" +- [yolk sac hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002354) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [MHC protein complex](http://purl.obolibrary.org/obo/GO_0042611) -- [ureter luminal urothelium](http://purl.obolibrary.org/obo/UBERON_0011947) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [yolk sac hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002354) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) -- [ureter luminal urothelium](http://purl.obolibrary.org/obo/UBERON_0011947) [label](http://www.w3.org/2000/01/rdf-schema#label) "ureter luminal urothelium" +- [yolk sac hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002354) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part) some [receptor-type tyrosine-protein phosphatase C](http://purl.obolibrary.org/obo/PR_000001006) -- [ureter luminal urothelium](http://purl.obolibrary.org/obo/UBERON_0011947) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [pheno_slim](http://purl.obolibrary.org/obo/uberon/core#pheno_slim) +#### Added +- [yolk sac hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002354) EquivalentTo [gestational hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002352) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC protein complex](http://purl.obolibrary.org/obo/GO_0042611)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C](http://purl.obolibrary.org/obo/PR_000001006)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD44 molecule](http://purl.obolibrary.org/obo/PR_000001307)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [complement component C1q receptor](http://purl.obolibrary.org/obo/PR_000002037)) -- Class: [ureter luminal urothelium](http://purl.obolibrary.org/obo/UBERON_0011947) +- [yolk sac hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002354) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [receptor-type tyrosine-protein phosphatase C](http://purl.obolibrary.org/obo/PR_000001006) -- [ureter luminal urothelium](http://purl.obolibrary.org/obo/UBERON_0011947) EquivalentTo [luminal layer of epithelium](http://purl.obolibrary.org/obo/UBERON_0011945) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [ureter](http://purl.obolibrary.org/obo/UBERON_0000056)) +- [yolk sac hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002354) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6A-2/6E-1](http://purl.obolibrary.org/obo/PR_000002979) -- [ureter luminal urothelium](http://purl.obolibrary.org/obo/UBERON_0011947) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [urothelium of ureter](http://purl.obolibrary.org/obo/UBERON_0001254) +- [yolk sac hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0002354) SubClassOf [lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [MHC protein complex](http://purl.obolibrary.org/obo/GO_0042611) -- [ureter luminal urothelium](http://purl.obolibrary.org/obo/UBERON_0011947) SubClassOf [luminal layer of epithelium](http://purl.obolibrary.org/obo/UBERON_0011945) +### zona pellucida `http://purl.obolibrary.org/obo/UBERON_0000086` +#### Removed +- [zona pellucida](http://purl.obolibrary.org/obo/UBERON_0000086) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) -### vasa recta ascending limb cell `http://purl.obolibrary.org/obo/CL_1001131` +- [zona pellucida](http://purl.obolibrary.org/obo/UBERON_0000086) SubClassOf [acellular anatomical structure](http://purl.obolibrary.org/obo/UBERON_0000476) #### Added -- [vasa recta ascending limb cell](http://purl.obolibrary.org/obo/CL_1001131) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A cell that is part of some vasa recta ascending limb." +- [zona pellucida](http://purl.obolibrary.org/obo/UBERON_0000086) SubClassOf [acellular membrane](http://purl.obolibrary.org/obo/UBERON_0005764) -- [vasa recta ascending limb cell](http://purl.obolibrary.org/obo/CL_1001131) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "It is known in some mammalian species that this cell may express PV-1, a component of the fenestral diaphragm." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20392798"^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:26062876"^^[string](http://www.w3.org/2001/XMLSchema#string) - - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20392799"^^[string](http://www.w3.org/2001/XMLSchema#string) +### zwitterion `http://purl.obolibrary.org/obo/CHEBI_27369` +#### Removed +- [zwitterion](http://purl.obolibrary.org/obo/CHEBI_27369) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "compose zwitterionique" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" +- [zwitterion](http://purl.obolibrary.org/obo/CHEBI_27369) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "zwitteriones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -### vasa recta descending limb cell `http://purl.obolibrary.org/obo/CL_1001285` +- [zwitterion](http://purl.obolibrary.org/obo/CHEBI_27369) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "zwitterions" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -#### Added -- [vasa recta descending limb cell](http://purl.obolibrary.org/obo/CL_1001285) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A cell that is part of some vasa recta descending limb." + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) -- [vasa recta descending limb cell](http://purl.obolibrary.org/obo/CL_1001285) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "It is known in some mammalian species that this cell may express the urea transporter B." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20392798"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [zwitterion](http://purl.obolibrary.org/obo/CHEBI_27369) [label](http://www.w3.org/2000/01/rdf-schema#label) "zwitterion" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:26062876"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [zwitterion](http://purl.obolibrary.org/obo/CHEBI_27369) [has_exact_synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "zwitterion" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20392799"^^[string](http://www.w3.org/2001/XMLSchema#string) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [IUPAC_NAME](http://purl.obolibrary.org/obo/chebi#IUPAC_NAME) +- [zwitterion](http://purl.obolibrary.org/obo/CHEBI_27369) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer)." -### vein endothelial cell of respiratory system `http://purl.obolibrary.org/obo/CL_4033008` +- [zwitterion](http://purl.obolibrary.org/obo/CHEBI_27369) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "chebi_ontology" -#### Added -- [vein endothelial cell of respiratory system](http://purl.obolibrary.org/obo/CL_4033008) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A(n) vein endothelial cell that is part of a(n) respiratory system."^^[string](http://www.w3.org/2001/XMLSchema#string) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:34030460"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [zwitterion](http://purl.obolibrary.org/obo/CHEBI_27369) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "compuestos zwitterionicos" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [vein endothelial cell of respiratory system](http://purl.obolibrary.org/obo/CL_4033008) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) +- [zwitterion](http://purl.obolibrary.org/obo/CHEBI_27369) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [_STAR](http://purl.obolibrary.org/obo/chebi#3_STAR) -- [vein endothelial cell of respiratory system](http://purl.obolibrary.org/obo/CL_4033008) [label](http://www.w3.org/2000/01/rdf-schema#label) "vein endothelial cell of respiratory system"^^[string](http://www.w3.org/2001/XMLSchema#string) +- [zwitterion](http://purl.obolibrary.org/obo/CHEBI_27369) [id](http://www.geneontology.org/formats/oboInOwl#id) "CHEBI:27369" -- Class: [vein endothelial cell of respiratory system](http://purl.obolibrary.org/obo/CL_4033008) +- [zwitterion](http://purl.obolibrary.org/obo/CHEBI_27369) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "zwitterionic compounds" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IUPAC" -- [vein endothelial cell of respiratory system](http://purl.obolibrary.org/obo/CL_4033008) EquivalentTo [vein endothelial cell](http://purl.obolibrary.org/obo/CL_0002543) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [respiratory system](http://purl.obolibrary.org/obo/UBERON_0001004)) +- Class: [zwitterion](http://purl.obolibrary.org/obo/CHEBI_27369) -- [vein endothelial cell of respiratory system](http://purl.obolibrary.org/obo/CL_4033008) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [respiratory system](http://purl.obolibrary.org/obo/UBERON_0001004) +- [zwitterion](http://purl.obolibrary.org/obo/CHEBI_27369) SubClassOf [dipolar compound](http://purl.obolibrary.org/obo/CHEBI_51151) -- [vein endothelial cell of respiratory system](http://purl.obolibrary.org/obo/CL_4033008) SubClassOf [vein endothelial cell](http://purl.obolibrary.org/obo/CL_0002543) diff --git a/src/ontology/reports/cl-edit.owl-obo-report.tsv b/src/ontology/reports/cl-edit.owl-obo-report.tsv index 5b40e2f2c..4277ff465 100644 --- a/src/ontology/reports/cl-edit.owl-obo-report.tsv +++ b/src/ontology/reports/cl-edit.owl-obo-report.tsv @@ -350,14 +350,14 @@ WARN missing_definition CL:1001568 IAO:0000115 WARN missing_definition CL:4023032 IAO:0000115 WARN missing_definition CL:4023039 IAO:0000115 WARN missing_definition CL:4023057 IAO:0000115 +WARN missing_definition CL:4030044 IAO:0000115 +WARN missing_definition CL:4030045 IAO:0000115 +WARN missing_definition CL:4030046 IAO:0000115 WARN missing_definition IAO:0000115 IAO:0000115 WARN missing_definition IAO:0000424 IAO:0000115 WARN missing_definition IAO:0000700 IAO:0000115 WARN missing_definition IAO:0100001 IAO:0000115 WARN missing_definition obo:cl#abbreviation IAO:0000115 -WARN missing_definition obo:cl#has_not_completed IAO:0000115 -WARN missing_definition obo:cl#lacks_part IAO:0000115 -WARN missing_definition obo:cl#lacks_plasma_membrane_part IAO:0000115 WARN missing_definition obo:uberon#HUMAN_PREFERRED IAO:0000115 WARN missing_definition obo:uberon#LATIN IAO:0000115 WARN missing_definition obo:uberon#PLURAL IAO:0000115 @@ -375,6 +375,7 @@ WARN missing_definition oboInOwl:inSubset IAO:0000115 WARN missing_definition oboInOwl:shorthand IAO:0000115 WARN missing_synonymtype_declaration obo:caloha-reqs-vetted#PLURAL rdfs:subPropertyOf WARN missing_synonymtype_declaration obo:cl#PLURAL rdfs:subPropertyOf +WARN missing_synonymtype_declaration obo:uberon/core#PLURAL rdfs:subPropertyOf INFO lowercase_definition CL:4023080 IAO:0000115 a L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex that has stellate pyramidal morphology. INFO lowercase_definition CL:4023081 IAO:0000115 a L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex that has inverted pyramidal morphology. INFO lowercase_definition CL:4023127 IAO:0000115 a KNDy neuron that is located in the arcuate nucleus of the hypothalamus. @@ -510,6 +511,7 @@ INFO missing_superclass CL:0004247 rdfs:subClassOf INFO missing_superclass CL:0005018 rdfs:subClassOf INFO missing_superclass CL:0005023 rdfs:subClassOf INFO missing_superclass CL:0008003 rdfs:subClassOf +INFO missing_superclass CL:0008007 rdfs:subClassOf INFO missing_superclass CL:0008008 rdfs:subClassOf INFO missing_superclass CL:0008009 rdfs:subClassOf INFO missing_superclass CL:0008010 rdfs:subClassOf @@ -859,3 +861,10 @@ INFO missing_superclass CL:4033010 rdfs:subClassOf INFO missing_superclass CL:4033011 rdfs:subClassOf INFO missing_superclass CL:4033012 rdfs:subClassOf INFO missing_superclass CL:4033013 rdfs:subClassOf +INFO missing_superclass CL:4033015 rdfs:subClassOf +INFO missing_superclass CL:4033017 rdfs:subClassOf +INFO missing_superclass CL:4033020 rdfs:subClassOf +INFO missing_superclass CL:4033021 rdfs:subClassOf +INFO missing_superclass CL:4033022 rdfs:subClassOf +INFO missing_superclass CL:4033025 rdfs:subClassOf +INFO missing_superclass CL:4033026 rdfs:subClassOf