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AF2 dl-binder-design vs binder design colab #1

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Abhi5ingh opened this issue Oct 21, 2024 · 0 comments
Open

AF2 dl-binder-design vs binder design colab #1

Abhi5ingh opened this issue Oct 21, 2024 · 0 comments

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@Abhi5ingh
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Hi Firstly thank you for your amazing work.
I had a question regarding your implementation, I am running the entire binder design pipeline on my hpc based on the pipeline given my baker lab for RFDiffusion on their git using dl-binder-design.
When i compare my results from the dl-binder-design repo and your notebook's AF prediction your notebook gives much better results, the af2 of dl-binder-design puts a lot of distance/residue gap between the target and the binder. I wanted your advice on how i can replicate your AF results if i run locally or on my hpc.
Any help or advice would be much appreciated :)
Thank you againn!

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