diff --git a/src/NetAnalyzers/Core/Microsoft.NetCore.Analyzers/Runtime/UseExceptionThrowHelpers.cs b/src/NetAnalyzers/Core/Microsoft.NetCore.Analyzers/Runtime/UseExceptionThrowHelpers.cs
index cad24dfbb2..c789078f2a 100644
--- a/src/NetAnalyzers/Core/Microsoft.NetCore.Analyzers/Runtime/UseExceptionThrowHelpers.cs
+++ b/src/NetAnalyzers/Core/Microsoft.NetCore.Analyzers/Runtime/UseExceptionThrowHelpers.cs
@@ -180,7 +180,8 @@ aooreThrowIfGreaterThan is not null || aooreThrowIfGreaterThanOrEqual is not nul
                     if (SymbolEqualityComparer.Default.Equals(objectCreationOperation.Type, ane))
                     {
                         if (aneThrowIfNull is not null &&
-                            IsParameterNullCheck(condition.Condition, out IParameterReferenceOperation? nullCheckParameter))
+                            IsParameterNullCheck(condition.Condition, out IParameterReferenceOperation? nullCheckParameter) &&
+                            nullCheckParameter.Type.IsReferenceType)
                         {
                             context.ReportDiagnostic(condition.CreateDiagnostic(
                                 UseArgumentNullExceptionThrowIfNullRule,
diff --git a/src/NetAnalyzers/UnitTests/Microsoft.NetCore.Analyzers/Runtime/UseExceptionThrowHelpersTests.cs b/src/NetAnalyzers/UnitTests/Microsoft.NetCore.Analyzers/Runtime/UseExceptionThrowHelpersTests.cs
index ee37f3d144..321565cd5f 100644
--- a/src/NetAnalyzers/UnitTests/Microsoft.NetCore.Analyzers/Runtime/UseExceptionThrowHelpersTests.cs
+++ b/src/NetAnalyzers/UnitTests/Microsoft.NetCore.Analyzers/Runtime/UseExceptionThrowHelpersTests.cs
@@ -177,6 +177,39 @@ string this[string name]
             return name;
         }
     }
+
+    void NullableArg(int? arg)
+    {
+        if (arg is null) throw new ArgumentNullException(nameof(arg));
+    }
+
+    void GenericMethod<T>(T arg)
+    {
+        if (arg is null) throw new ArgumentNullException(nameof(arg));
+    }
+
+    void GenericMethodWithClassConstraint<T>(T arg) where T : class
+    {
+        {|CA1510:if (arg is null) throw new ArgumentNullException(nameof(arg));|}
+    }
+
+    void GenericMethodWithTypeConstraint<T>(T arg) where T : C
+    {
+        {|CA1510:if (arg is null) throw new ArgumentNullException(nameof(arg));|}
+    }
+
+    void GenericMethodWithInterfaceConstraint<T>(T arg) where T : IDisposable
+    {
+        if (arg is null) throw new ArgumentNullException(nameof(arg));
+    }
+}
+
+class GenericType<T>
+{
+    void M(T arg)
+    {
+        if (arg is null) throw new ArgumentNullException(nameof(arg));
+    }
 }
 ",
                 FixedCode =
@@ -260,6 +293,39 @@ string this[string name]
             return name;
         }
     }
+
+    void NullableArg(int? arg)
+    {
+        if (arg is null) throw new ArgumentNullException(nameof(arg));
+    }
+
+    void GenericMethod<T>(T arg)
+    {
+        if (arg is null) throw new ArgumentNullException(nameof(arg));
+    }
+
+    void GenericMethodWithClassConstraint<T>(T arg) where T : class
+    {
+        ArgumentNullException.ThrowIfNull(arg);
+    }
+
+    void GenericMethodWithTypeConstraint<T>(T arg) where T : C
+    {
+        ArgumentNullException.ThrowIfNull(arg);
+    }
+
+    void GenericMethodWithInterfaceConstraint<T>(T arg) where T : IDisposable
+    {
+        if (arg is null) throw new ArgumentNullException(nameof(arg));
+    }
+}
+
+class GenericType<T>
+{
+    void M(T arg)
+    {
+        if (arg is null) throw new ArgumentNullException(nameof(arg));
+    }
 }
 "
             }.RunAsync();