diff --git a/BinxelviewForm.cs b/BinxelviewForm.cs
index 9bfc0b8..c5b509d 100644
--- a/BinxelviewForm.cs
+++ b/BinxelviewForm.cs
@@ -1927,5 +1927,21 @@ private void dataGridPixel_CellValueChanged(object sender, DataGridViewCellEvent
                 redrawPixels();
             }
         }
+
+        protected override bool ProcessCmdKey(ref Message msg, Keys keyData)
+        {
+            // global hotkeys
+            switch (keyData)
+            {
+                case Keys.Control | Keys.O:
+                    openToolStripMenuItem_Click(this, null);
+                    return true;
+                case Keys.Control | Keys.R:
+                    reloadFileToolStripMenuItem_Click(this, null);
+                    return true;
+                default:
+                    return base.ProcessCmdKey(ref msg, keyData);
+            }
+        }
     }
 }
diff --git a/readme.txt b/readme.txt
index 3df7836..6bedf33 100644
--- a/readme.txt
+++ b/readme.txt
@@ -129,6 +129,15 @@ Custom palettes are 24-bit RGB triples (8 bits for each component).
 Click on a colour in the palette box to edit it.
 
 
+Hotkeys
+-------
+
+The following global hotkeys may be used:
+
+Ctrl+O - Open a new file.
+Ctrl+R - Reload the current file.
+
+
 Other Notes
 -----------
 
@@ -157,6 +166,7 @@ Changes
 - Maximum file size increased from 256MB to 2GB.
 - Right click context menu option to move position to the selected pixel.
 - File menu reload option.
+- Added global Ctrl hotkeys.
 
 1.5.0.0 (2020-07-31)
 - Twiddle option for inspecting textures stored with morton ordering of pixels.