diff --git a/thriftpy/http.py b/thriftpy/http.py
index 1e5a6c8..7cb2325 100644
--- a/thriftpy/http.py
+++ b/thriftpy/http.py
@@ -213,7 +213,7 @@ def flush(self):
         self.__wbuf = BytesIO()
 
         # HTTP request
-        self.__http.putrequest('POST', self.path)
+        self.__http.putrequest('POST', self.path, skip_host=True)
 
         # Write headers
         self.__http.putheader('Host', self.host)